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Emerging Roles of N6-Methyladenosine Modification in Neurodevelopment and Neurodegeneration

https://doi.org/10.3390/cells10102694
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53/53 checkable references clean · checked 2026-07-24

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

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The 53 checked references that resolve
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Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation
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Fto-modulated lipid niche regulates adult neurogenesis through modulating adenosine metabolism
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Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis
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N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications
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METTL3-mediated m6A modification is required for cerebellar development
resolves10.1186/s13059-018-1435-z
RNA m6A methylation participates in regulation of postnatal development of the mouse cerebellum
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Region-specific RNA m <sup>6</sup> A methylation represents a new layer of control in the gene regulatory network in the mouse brain
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Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System
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The role of m6A modification in physiology and disease
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m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade
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Inactivation of the Fto gene protects from obesity
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Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations
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resolves10.1038/ncomms2822
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resolves10.1038/s41586-018-0666-1
m6A facilitates hippocampus-dependent learning and memory through YTHDF1
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Ythdf2-mediated m6A mRNA clearance modulates neural development in mice
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Epitranscriptomes in the Adult Mammalian Brain: Dynamic Changes Regulate Behavior
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The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry
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The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation
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Dynamic m6A modification regulates local translation of mRNA in axons
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The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression
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Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts
resolves10.1016/j.neuron.2019.12.013
m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination
resolves10.1038/s41422-018-0113-8
A novel m6A reader Prrc2a controls oligodendroglial specification and myelination
resolves10.1038/s41422-018-0092-9
METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation
resolves10.1016/j.neuron.2018.06.007
Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning
resolves10.1523/JNEUROSCI.4053-15.2016
Experience-Dependent Accumulation of <i>N</i> <sup>6</sup> -Methyladenosine in the Prefrontal Cortex Is Associated with Memory Processes in Mice
resolves10.1038/nature15377
Dynamic m6A mRNA methylation directs translational control of heat shock response
resolves10.1016/j.neuron.2018.07.009
The Role of m6A/m-RNA Methylation in Stress Response Regulation
resolves10.1038/nrm.2016.132
Post-transcriptional gene regulation by mRNA modifications
resolves10.1007/s12035-018-1138-1
m6A RNA Methylation Controls Neural Development and Is Involved in Human Diseases
resolves10.3389/fnins.2020.00098
Abnormality of m6A mRNA Methylation Is Involved in Alzheimer’s Disease
resolves10.1111/gbb.12428
The emerging role of mRNA methylation in normal and pathological behavior
resolves10.1101/gad.262766.115
RNA <i>N</i><sup>6</sup>-methyladenosine methylation in post-transcriptional gene expression regulation
resolves10.1016/j.bbrc.2018.02.201
FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling
resolves10.1111/jcmm.16740
Conditional deficiency of m6A methyltransferase Mettl14 in substantia nigra alters dopaminergic neuron function
resolves10.1021/acschemneuro.8b00657
Down-Regulation of m6A mRNA Methylation Is Involved in Dopaminergic Neuronal Death
resolves10.1016/j.neurobiolaging.2020.03.018
Genetic analysis of N6-methyladenosine modification genes in Parkinson's disease
The 1 reference without a DOI — listed, not checked
no DOI — not checkedFragile X mental retardation protein modulates the stability of its m6A-marked messenger RNA targets
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