Reference health

Recombinant MPT83 Derived from <i>Mycobacterium tuberculosis</i> Induces Cytokine Production and Upregulates the Function of Mouse Macrophages through TLR2

https://doi.org/10.4049/jimmunol.1102177
CiteStamped reference-health badge
73/73 checkable references clean · checked 2026-07-22

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

7 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 73 checked references that resolve
resolves10.1146/annurev.immunol.21.120601.141126
Toll-Like Receptors
resolves10.1128/IAI.68.12.6883-6890.2000
Maturation of Human Dendritic Cells by Cell Wall Skeleton of<i>Mycobacterium bovis</i>Bacillus Calmette-Guérin: Involvement of Toll-Like Receptors
resolves10.1084/jem.142.1.1
Phagosome-lysosome interactions in cultured macrophages infected with virulent tubercle bacilli. Reversal of the usual nonfusion pattern and observations on bacterial survival.
resolves10.1128/iai.64.3.683-690.1996
Immunopathology of tuberculosis: roles of macrophages and monocytes
resolves10.1074/jbc.M102876200
1α,25-Dihydroxyvitamin D3-induced Monocyte Antimycobacterial Activity Is Regulated by Phosphatidylinositol 3-Kinase and Mediated by the NADPH-dependent Phagocyte Oxidase
resolves10.1128/IAI.73.10.7064-7068.2005
Mycobacterial Lipomannan Induces Matrix Metalloproteinase-9 Expression in Human Macrophagic Cells through a Toll-Like Receptor 1 (TLR1)/TLR2- and CD14-Dependent Mechanism
resolves10.1074/jbc.M604379200
Execution of Macrophage Apoptosis by PE_PGRS33 of Mycobacterium tuberculosis Is Mediated by Toll-like Receptor 2-dependent Release of Tumor Necrosis Factor-α
resolves10.1128/IAI.74.5.2686-2696.2006
The Mycobacterial 38-Kilodalton Glycolipoprotein Antigen Activates the Mitogen-Activated Protein Kinase Pathway and Release of Proinflammatory Cytokines through Toll-Like Receptors 2 and 4 in Human Monocytes
resolves10.4049/jimmunol.170.5.2409
The 19-kDa <i>Mycobacterium tuberculosis</i> Protein Induces Macrophage Apoptosis Through Toll-Like Receptor-2
resolves10.4049/jimmunol.178.5.3161
Mycobacterial Lipomannan Induces Granuloma Macrophage Fusion via a TLR2-Dependent, ADAM9- and β1 Integrin-Mediated Pathway
resolves10.4049/jimmunol.170.7.3451
Cutting Edge: A Toll-Like Receptor 2 Polymorphism That Is Associated with Lepromatous Leprosy Is Unable to Mediate Mycobacterial Signaling
resolves10.1183/09031936.03.00061703
The Arg753Gln polymorphism of the human Toll-like receptor 2 gene in tuberculosis disease
resolves10.4049/jimmunol.169.7.3480
Cutting Edge: Toll-Like Receptor (TLR)2- and TLR4-Mediated Pathogen Recognition in Resistance to Airborne Infection with <i>Mycobacterium tuberculosis</i>
resolves10.1111/j.0019-2805.2003.01807.x
Limited role of the Toll‐like receptor‐2 in resistance to <i>Mycobacterium avium</i>
resolves10.4049/jimmunol.172.7.4425
Toll-Like Receptor 2 (TLR2)-Dependent-Positive and TLR2-Independent-Negative Regulation of Proinflammatory Cytokines by Mycobacterial Lipomannans
resolves10.1189/jlb.69.6.1036
Different Toll-like receptor agonists induce distinct macrophage responses
resolves10.1074/jbc.M303446200
Acylation State of the Phosphatidylinositol Hexamannosides from Mycobacterium bovis Bacillus Calmette Guérin and Mycobacterium tuberculosis H37Rv and Its Implication in Toll-like Receptor Response
resolves10.4049/jimmunol.167.2.910
Toll-Like Receptor 2-Dependent Inhibition of Macrophage Class II MHC Expression and Antigen Processing by 19-kDa Lipoprotein of <i>Mycobacterium tuberculosis</i>
resolves10.4049/jimmunol.171.1.175
Inhibition of IFN-γ-Induced Class II Transactivator Expression by a 19-kDa Lipoprotein from <i>Mycobacterium tuberculosis</i> : A Potential Mechanism for Immune Evasion
resolves10.1128/IAI.71.8.4487-4497.2003
The<i>Mycobacterium tuberculosis</i>19-Kilodalton Lipoprotein Inhibits Gamma Interferon-Regulated HLA-DR and FcγR1 on Human Macrophages through Toll-Like Receptor 2
resolves10.4049/jimmunol.173.4.2660
<i>Mycobacterium tuberculosis</i> LprG ( <i>Rv1411c</i> ): A Novel TLR-2 Ligand That Inhibits Human Macrophage Class II MHC Antigen Processing
resolves10.4049/jimmunol.177.1.422
<i>Mycobacterium tuberculosis</i> LprA Is a Lipoprotein Agonist of TLR2 That Regulates Innate Immunity and APC Function
resolves10.1016/j.bbrc.2010.08.085
Non-acylated Mycobacterium bovis glycoprotein MPB83 binds to TLR1/2 and stimulates production of matrix metalloproteinase 9
resolves10.1111/j.1365-3083.2008.02193.x
<i>Mycobacterium tuberculosis</i> 38‐kDa Lipoprotein is Apoptogenic for Human Monocyte‐derived Macrophages
resolves10.4049/jimmunol.167.6.3339
Mycobacteria-Induced TNF-α and IL-10 Formation by Human Macrophages Is Differentially Regulated at the Level of Mitogen-Activated Protein Kinase Activity
resolves10.1016/S0955-0674(97)80061-0
Mitogen-activated protein kinase pathways
resolves10.4049/jimmunol.156.12.4867
Activation of a p38 mitogen-activated protein kinase in human neutrophils by lipopolysaccharide
resolves10.1038/372739a0
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
resolves10.4049/jimmunol.162.1.372
Activation of Human CD8+ αβ TCR+ Cells by <i>Mycobacterium tuberculosis</i> Via an Alternate Class I MHC Antigen-Processing Pathway
resolves10.4049/jimmunol.154.4.1786
CD4+  <i>alpha</i>  <i>beta</i> T cell and gamma delta T cell responses to <i>Mycobacterium tuberculosis</i>. Similarities and differences in Ag recognition, cytotoxic effector function, and cytokine production.
resolves10.1146/annurev.immunol.15.1.749
CELLULAR RESPONSES TO INTERFERON-γ
resolves10.1084/jem.175.4.1111
Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages.
resolves10.1046/j.1365-2249.1998.00554.x
Differential potentiation of anti-mycobacterial activity and reactive nitrogen intermediate-producing ability of murine peritoneal macrophages activated by interferon-gamma (IFN-γ) and tumour necrosis factor-alpha (TNF-α)
resolves10.1084/jem.178.6.2243
Disseminated tuberculosis in interferon gamma gene-disrupted mice.
resolves10.1056/NEJM199612263352602
A Mutation in the Interferon-γ –Receptor Gene and Susceptibility to Mycobacterial Infection
resolves10.1128/IAI.72.11.6603-6614.2004
Prolonged Toll-Like Receptor Signaling by<i>Mycobacterium tuberculosis</i>and Its 19-Kilodalton Lipoprotein Inhibits Gamma Interferon-Induced Regulation of Selected Genes in Macrophages
resolves10.4049/jimmunol.176.7.4323
<i>Mycobacterium tuberculosis</i> 19-kDa Lipoprotein Inhibits IFN-γ-Induced Chromatin Remodeling of <i>MHC2TA</i> by TLR2 and MAPK Signaling
resolves10.1046/j.1365-3083.1996.d01-61.x
Heterogenous Expression of the Related MBP70 and MPB83 Proteins Distinguish Various Substrains of <i>Mycobacterium bovis</i> BCG and <i>Mycobacterium tuberculosis</i> H37Rv
resolves10.1128/cdli.1.5.608-611.1994
Immunoblot analysis of humoral immune responses to Mycobacterium bovis in experimentally infected cattle: early recognition of a 26-kilodalton antigen
resolves10.1128/CDLI.6.5.675-682.1999
Development of Diagnostic Reagents To Differentiate between<i>Mycobacterium bovis</i>BCG Vaccination and<i>M. bovis</i>Infection in Cattle
resolves10.1016/j.vaccine.2005.03.025
Combined DNA vaccines formulated either in DDA or in saline protect cattle from Mycobacterium bovis infection
resolves10.1016/j.vaccine.2007.06.061
A combined DNA vaccine enhances protective immunity against Mycobacterium tuberculosis and Brucella abortus in the presence of an IL-12 expression vector
resolves10.1016/j.vaccine.2008.12.055
Immunotherapy with combined DNA vaccines is an effective treatment for M. bovis infection in cattle
resolves10.1146/annurev.immunol.14.1.649
THE NF-κB AND IκB PROTEINS: New Discoveries and Insights
resolves10.1146/annurev.immunol.16.1.225
NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses
resolves10.4049/jimmunol.1000773
The PPE18 Protein of <i>Mycobacterium tuberculosis</i> Inhibits NF-κB/rel–Mediated Proinflammatory Cytokine Production by Upregulating and Phosphorylating Suppressor of Cytokine Signaling 3 Protein
resolves10.1128/MCB.15.10.5258
Regulation of Interleukin 12 p40 Expression through an NF-κB Half-Site
resolves10.1073/pnas.230436397
Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages
resolves10.4049/jimmunol.151.12.6986
Pyrrolidine dithiocarbamate inhibits NF-<i>kappa</i> B mobilization and TNF production in human monocytes.
resolves10.4049/jimmunol.157.11.5022
Corynebacterium parvum- and Mycobacterium bovis bacillus Calmette-Guerin-induced granuloma formation is inhibited in TNF receptor I (TNF-RI) knockout mice and by treatment with soluble TNF-RI
resolves10.4049/jimmunol.168.9.4620
TNF Regulates Chemokine Induction Essential for Cell Recruitment, Granuloma Formation, and Clearance of Mycobacterial Infection
resolves10.1038/ng0902-97
Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae
resolves10.4049/jimmunol.166.12.7033
Infection of Human Macrophages and Dendritic Cells with <i>Mycobacterium tuberculosis</i> Induces a Differential Cytokine Gene Expression That Modulates T Cell Response
resolves10.1073/pnas.022649799
Human macrophage activation programs induced by bacterial pathogens
resolves10.1006/mpat.1999.0345
Secretion of cytokines by human macrophages upon infection by pathogenic and non-pathogenic mycobacteria
resolves10.1007/BF01715538
Release of TNFα and IL6 from human monocytes infected withMycobacterium kansasii: A comparison toMycobacterium avium
resolves10.1099/00222615-40-2-129
Induction of IL-1 , IL-6, TNF- , GM-CSF and G-CSF in human macrophages by smooth transparent and smooth opaque colonial variants of Mycobacterium avium
resolves10.1016/S1471-4906(03)00242-4
Leucine-rich repeats and pathogen recognition in Toll-like receptors
resolves10.1038/ni1468
Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages
resolves10.4049/jimmunol.0901367
The PPE18 of <i>Mycobacterium tuberculosis</i> Interacts with TLR2 and Activates IL-10 Induction in Macrophage
resolves10.1189/jlb.71.3.503
Toll-like receptor 2 (TLR2) mediates activation of stress-activated MAP kinase p38
resolves10.1128/IAI.69.4.2270-2276.2001
Micrococci and Peptidoglycan Activate TLR2→MyD88→IRAK→TRAF→NIK→IKK→NF-κB Signal Transduction Pathway That Induces Transcription of Interleukin-8
resolves10.1126/science.1164860
Pulsatile Stimulation Determines Timing and Specificity of NF-κB-Dependent Transcription
resolves10.1002/1521-4141(200106)31:6<1883::AID-IMMU1883>3.0.CO;2-V
Role of NFκB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI
resolves10.1038/nm1201-1291
Possible new role for NF-κB in the resolution of inflammation
resolves10.1073/pnas.86.11.4240
Interleukin 2 acts as an adjuvant to increase the potency of inactivated rabies virus vaccine.
resolves10.4049/jimmunol.163.7.3898
<i>Mycobacterium tuberculosis</i> Inhibits IFN-γ Transcriptional Responses Without Inhibiting Activation of STAT1
resolves10.4049/jimmunol.149.1.65
Signals delivered via MHC class II molecules synergize with signals delivered via TCR/CD3 to cause proliferation and cytokine gene expression in T cells
resolves10.1002/eji.1830231139
Engagement of major histocompatibility complex class II molecules leads to nitrite production in bone marrow‐derived macrophages
resolves10.1084/jem.172.5.1513
Engagement of major histocompatibility complex class II molecules induces sustained, lymphocyte function-associated molecule 1-dependent cell adhesion.
resolves10.1038/ni.2015
Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk
resolves10.1046/j.1365-2249.2000.01212.x
The 19-kD antigen and protective immunity in a murine model of tuberculosis
resolves10.4049/jimmunol.179.10.6910
CCAAT/Enhancer-Binding Protein β and δ Binding to CIITA Promoters Is Associated with the Inhibition of CIITA Expression in Response to <i>Mycobacterium tuberculosis</i> 19-kDa Lipoprotein
The 7 references without a DOI — listed, not checked
no DOI — not checkedThe immunobiology of the mycobacterial infected macrophage
no DOI — not checkedToll-like receptor 2 Arg677Trp polymorphism is associated with susceptibility to tuberculosis in Tunisian patients
no DOI — not checkedGeneration of nitric oxide and clearance of interferon-gamma after BCG infection are impaired in mice that lack the interferon-gamma receptor
no DOI — not checkedDisseminated bacille Calmette-Guérin infection in an infant with a novel deletion in the interferon-gamma receptor gene
no DOI — not checkedCloning, expression and identification of Mycobacterium tuberculosis protein MPT83 in eukaryotic expression vector and prokaryotic expression vector
no DOI — not checkedDifferential release of tumor necrosis factor-alpha from murine peritoneal macrophages stimulated with virulent and avirulent species of mycobacteria
no DOI — not checkedFunction of NF-kappa B/Rel binding sites in the major histocompatibility complex class II invariant chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

checked 2026-07-22 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record

Embed this badge

Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.

<a href="https://citestamp.com/citestamped/10.4049/jimmunol.1102177"><img src="https://citestamp.com/citestamped/10.4049/jimmunol.1102177/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[![CiteStamped reference-health badge](https://citestamp.com/citestamped/10.4049/jimmunol.1102177/badge.svg)](https://citestamp.com/citestamped/10.4049/jimmunol.1102177)