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Tumor Suppressor p53 Inhibits Systemic Autoimmune Diseases by Inducing Regulatory T Cells

https://doi.org/10.4049/jimmunol.1300509
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42/42 checkable references clean · checked 2026-07-24

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

3 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 42 checked references that resolve
resolves10.1016/j.cell.2009.04.037
Blinded by the Light: The Growing Complexity of p53
resolves10.1038/nature07986
Cytoplasmic functions of the tumour suppressor p53
resolves10.1002/eji.200425371
Monoclonal antibody to a DNA‐binding domain of p53 mimics charge structure of DNA: anti‐idiotypes to the anti‐p53 antibody are anti‐DNA
resolves10.1073/pnas.94.20.10895
Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium
resolves10.1073/pnas.152333199
Regional analysis of <i>p53</i> mutations in rheumatoid arthritis synovium
resolves10.1002/art.21099
Regulation of arthritis by p53: Critical role of adaptive immunity
resolves10.1111/j.1365-2249.2008.03629.x
The tumour suppressor gene p53 modulates the severity of antigen-induced arthritis and the systemic immune response
resolves10.1016/S0165-5728(02)00428-9
Regulatory role of p53 in experimental autoimmune encephalomyelitis
resolves10.2337/diabetes.54.5.1423
Tumor Suppressor p53 Inhibits Autoimmune Inflammation and Macrophage Function
resolves10.1096/fj.10-175299
Trp53 negatively regulates autoimmunity <i>via</i> the STAT3‐Th17 axis
resolves10.1038/ni904
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
resolves10.1126/science.1079490
Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>
resolves10.1146/annurev-immunol-020711-075043
Induced CD4<sup>+</sup>Foxp3<sup>+</sup>Regulatory T Cells in Immune Tolerance
resolves10.1074/jbc.M109.047985
Foxp3 Expression in p53-dependent DNA Damage Responses
resolves10.4049/jimmunol.0900753
CD4+CD25+ Regulatory T Cells Resist a Novel Form of CD28- and Fas-Dependent p53-Induced T Cell Apoptosis
resolves10.1016/S1074-7613(01)00227-8
A Critical Role for Dnmt1 and DNA Methylation in T Cell Development, Function, and Survival
resolves10.1101/gad.14.8.994
Induction of medulloblastomas in<i>p53</i>-null mutant mice by somatic inactivation of<i>Rb</i>in the external granular layer cells of the cerebellum
resolves10.1093/intimm/dxp037
Protein geranylgeranylation regulates the balance between Th17 cells and Foxp3+ regulatory T cells
resolves10.1016/1074-7613(94)90045-0
Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells
resolves10.1016/S0022-3565(24)35257-7
Specific Type IV Phosphodiesterase Inhibitor Rolipram Mitigates Experimental Colitis in Mice
resolves10.1371/journal.pone.0025412
Tumor Suppressor p53 Functions as a Negative Regulator in IgE-Mediated Mast Cell Activation
resolves10.1084/jem.20070109
CREB/ATF-dependent T cell receptor–induced <i>FoxP3</i> gene expression: a role for DNA methylation
resolves10.1038/ni1549
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
resolves10.1189/jlb.0909639
c-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-β inhibits c-Maf-induced IL-21 production in CD4+ T cells
resolves10.4049/jimmunol.163.4.1966
Accelerated Development and Aging of the Immune System in p53-Deficient Mice
resolves10.1146/annurev.immunol.23.021704.115806
INTERLEUKIN-6: From Basic Science to Medicine—40 Years in Immunology
resolves10.4049/jimmunol.173.11.6526
Cutting Edge: TGF-β Signaling Is Required for the In Vivo Expansion and Immunosuppressive Capacity of Regulatory CD4+CD25+ T Cells
resolves10.1016/j.immuni.2009.05.001
Plasticity of CD4+ T Cell Lineage Differentiation
resolves10.1111/j.0105-2896.2006.00427.x
Foxp3<sup>+</sup>CD25<sup>+</sup>CD4<sup>+</sup> natural regulatory T cells in dominant self‐tolerance and autoimmune disease
resolves10.4049/jimmunol.163.11.5813
Protein Kinase Cθ Cooperates with Calcineurin to Induce Fas Ligand Expression During Activation-Induced T Cell Death
resolves10.1146/annurev.immunol.021908.132706
T Cell Activation
resolves10.2217/14622416.8.11.1485
<i>FOXP3</i> and Breast Cancer: Implications for Therapy and Diagnosis
resolves10.1158/0008-5472.CAN-06-3304
Foxp3 Expression in Pancreatic Carcinoma Cells as a Novel Mechanism of Immune Evasion in Cancer
resolves10.1186/1479-5876-6-19
Foxp3 expression in human cancer cells
resolves10.1038/nature08750
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
resolves10.1177/0961203311434941
Associations between the p53 codon 72 polymorphisms and susceptibility to systemic lupus erythematosus and rheumatoid arthritis: a meta-analysis
resolves10.1038/72272
The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development
resolves10.4049/jimmunol.167.7.4067
Role of Cyclin Kinase Inhibitor p21 in Systemic Autoimmunity
resolves10.1016/S1074-7613(02)00302-3
Mice Lacking the p53-Effector Gene Gadd45a Develop a Lupus-Like Syndrome
resolves10.4049/jimmunol.178.1.280
IL-2 Receptor β-Dependent STAT5 Activation Is Required for the Development of Foxp3+ Regulatory T Cells
resolves10.1016/j.immuni.2008.07.018
Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction
resolves10.1038/nature10772
Extrathymically generated regulatory T cells control mucosal TH2 inflammation
The 3 references without a DOI — listed, not checked
no DOI — not checkedAnti-p53 autoantibody in systemic sclerosis: association with limited cutaneous systemic sclerosis
no DOI — not checkedFOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2
no DOI — not checkedPillars article: immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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