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Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer

https://doi.org/10.4049/jimmunol.182.3.1746
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The 73 references without a DOI — listed, not checked
no DOI — not checkedRegulatory T cells in the control of immune pathology.
no DOI — not checkedImmunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.
no DOI — not checkedRegulatory T cells in autoimmmunity.
no DOI — not checkedControl of regulatory T cell development by the transcription factor Foxp3.
no DOI — not checkedNatural regulatory T cells in infectious disease.
no DOI — not checkedNaturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self.
no DOI — not checkedRegulatory T cells and immune tolerance.
no DOI — not checkedRegulatory T cells and cancer.
no DOI — not checkedSpecific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival.
no DOI — not checkedIncreased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients.
no DOI — not checkedPrevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions.
no DOI — not checkedThe expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.
no DOI — not checkedDynamics of the immune reaction to pancreatic cancer from inception to invasion.
no DOI — not checkedFrequencies and role of regulatory T cells in patients with (pre)malignant cervical neoplasia.
no DOI — not checkedCD4+CD25+FoxP3+ T-cell infiltration and heme oxygenase-1 expression correlate with tumor grade in human gliomas.
no DOI — not checkedCD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo.
no DOI — not checkedIntratumoral FOXP3 expression in infiltrating breast carcinoma: its association with clinicopathologic parameters and angiogenesis.
no DOI — not checkedHomeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of b16 melanoma.
no DOI — not checkedIL-2 immunotoxin therapy modulates tumor-associated regulatory T cells and leads to lasting immune-mediated rejection of breast cancers in neu-transgenic mice.
no DOI — not checkedCD25+CD4+ regulatory T-cells in cancer.
no DOI — not checkedTumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor α) monoclonal antibody.
no DOI — not checkedDepletion of CD4+CD25+ regulatory T cells promotes a tumor-specific immune response in pancreas cancer-bearing mice.
no DOI — not checkedEnhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells.
no DOI — not checkedInduction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity.
no DOI — not checkedTumor cells convert immature myeloid dendritic cells into TGF-β-secreting cells inducing CD4+CD25+ regulatory T cell proliferation.
no DOI — not checkedTreatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells.
no DOI — not checkedStimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance.
no DOI — not checkedConcomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells.
no DOI — not checkedSynergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25+ regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses.
no DOI — not checkedCyclophosphamide (Cy)-facilitated adoptive immunotherapy of a Cy-resistant tumor: evidence that Cy permits the expression of adoptive T-cell mediated immunity by removing suppressor T cells rather than by reducing tumor burden.
no DOI — not checkedCyclophosphamide-induced immunologically mediated regression of a cyclophosphamide-resistant murine tumor: a consequence of eliminating precursor L3T4+ suppressor T-cells.
no DOI — not checkedMetronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients.
no DOI — not checkedCyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells.
no DOI — not checkedHoming to suppress: address codes for Treg migration.
no DOI — not checkedSystemic and local characterization of regulatory T cells in a chronic fungal infection in humans.
no DOI — not checkedTherapy for pneumonitis and sialadenitis by accumulation of CCR2-expressing CD4+CD25+ regulatory T cells in MRL/lpr mice.
no DOI — not checkedCritical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease.
no DOI — not checkedCCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence.
no DOI — not checkedCCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer.
no DOI — not checkedUnique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4+CD25+ regulatory T cells.
no DOI — not checkedAlloantigen-enhanced accumulation of CCR5+“effector” regulatory T cells in the gravid uterus.
no DOI — not checkedThe majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors.
no DOI — not checkedCCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T-cell subset.
no DOI — not checkedDistinctive role of CCR7 in migration and functional activity of naive- and effector/memory-like Treg subsets.
no DOI — not checkedPrevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma.
no DOI — not checkedInduction and chemotherapeutic response of two transplantable ductal adenocarcinomas of the pancreas in C57BL/6 mice.
no DOI — not checkedIncreased prevalence of regulatory T cells (Treg) is induced by pancreas adenocarcinoma.
no DOI — not checkedCre-lox-regulated conditional RNA interference from transgenes.
no DOI — not checkedDiscovery of novel, potent, and selective small-molecule CCR5 antagonists as anti-HIV-1 agents: synthesis and biological evaluation of anilide derivatives with a quaternary ammonium moiety.
no DOI — not checkedA small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity.
no DOI — not checkedThe unique target specificity of a nonpeptide chemokine receptor antagonist: selective blockade of two Th1 chemokine receptors CCR5 and CXCR3.
no DOI — not checkedRegulatory-T-cell inhibition versus depletion: the right choice in cancer immunotherapy.
no DOI — not checkedHost absence of CCR5 potentiates dendritic cell vaccination.
no DOI — not checkedMesenchymal stem cells within tumour stroma promote breast cancer metastasis.
no DOI — not checkedSelective infiltration of CCR5+CXCR3+ T lymphocytes in human colorectal carcinoma.
no DOI — not checkedExpression of CCL5 (RANTES) and CCR5 in prostate cancer.
no DOI — not checkedPrognostic significance of expression of CCL5/RANTES receptors in patients with gastric cancer.
no DOI — not checkedA comprehensive in vitro characterization of pancreatic ductal carcinoma cell line biological behavior and its correlation with the structural and genetic profile.
no DOI — not checkedRole of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model.
no DOI — not checkedA non-peptide CCR5 antagonist inhibits collagen-induced arthritis by modulating T cell migration without affecting anti-collagen T cell responses.
no DOI — not checkedA pivotal role for CC chemokine receptor 5 in T-cell migration to tumor sites induced by interleukin 12 treatment in tumor-bearing mice.
no DOI — not checkedTherapeutic effect of CXCR3-expressing regulatory T cells on liver, lung and intestinal damages in a murine acute GVHD model.
no DOI — not checkedGenome-wide expression profiling during protection from colitis by regulatory T cells.
no DOI — not checkedEffect of a CC chemokine receptor antagonist on collagen induced arthritis in DBA/1 mice.
no DOI — not checkedA chemokine receptor antagonist inhibits experimental breast tumor growth.
no DOI — not checkedComprehensive mapping of poxvirus vCCI chemokine-binding protein: expanded range of ligand interactions and unusual dissociation kinetics.
no DOI — not checkedMembrane-bound CC chemokine inhibitor 35K provides localized inhibition of CC chemokine activity in vitro and in vivo.
no DOI — not checkedViral chemokine-binding proteins.
no DOI — not checkedCCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers.
no DOI — not checkedChemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice.
no DOI — not checkedMast cells are essential intermediaries in regulatory T-cell tolerance.
no DOI — not checkedMesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer.
no DOI — not checkedMesothelin-specific CD8+ T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients.
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