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Exploring the Role of Spatial Confinement in Immune Cell Recruitment and Regeneration of Skin Wounds

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/adfm.201900071openalex-snapshot
Scalable High‐Throughput Production of Modular Microgels for In Situ Assembly of Microporous Tissue Scaffolds
inferredcites →https://doi.org/10.1002/adhm.201700254openalex-snapshot
Clickable Microgel Scaffolds as Platforms for 3D Cell Encapsulation
inferredcites →https://doi.org/10.1002/adhm.201700289openalex-snapshot
Integrin‐Mediated Interactions Control Macrophage Polarization in 3D Hydrogels
inferredcites →https://doi.org/10.1002/adhm.201800160openalex-snapshot
Assembly of PEG Microgels into Porous Cell‐Instructive 3D Scaffolds via Thiol‐Ene Click Chemistry
inferredcites →https://doi.org/10.1002/adhm.202100644openalex-snapshot
3D Printing of Microgel Scaffolds with Tunable Void Fraction to Promote Cell Infiltration
inferredcites →https://doi.org/10.1002/adhm.202200989openalex-snapshot
Annealing High Aspect Ratio Microgels into Macroporous 3D Scaffolds Allows for Higher Porosities and Effective Cell Migration
inferredcites →https://doi.org/10.1002/adhm.202202239openalex-snapshot
Multisized Photoannealable Microgels Regulate Cell Spreading, Aggregation, and Macrophage Phenotype through Microporous Void Space
inferredcites →https://doi.org/10.1002/adhm.202300823openalex-snapshot
Spatial Confinement Modulates Macrophage Response in Microporous Annealed Particle (MAP) Scaffolds
inferredcites →https://doi.org/10.1002/adma.202109194openalex-snapshot
Anisotropic Rod‐Shaped Particles Influence Injectable Granular Hydrogel Properties and Cell Invasion
inferredcites →https://doi.org/10.1002/adma.202270092openalex-snapshot
Anisotropic Rod‐Shaped Particles Influence Injectable Granular Hydrogel Properties and Cell Invasion (Adv. Mater. 12/2022)
inferredcites →https://doi.org/10.1002/advs.201900520openalex-snapshot
Adaptable Microporous Hydrogels of Propagating NGF‐Gradient by Injectable Building Blocks for Accelerated Axonal Outgrowth
inferredcites →https://doi.org/10.1002/advs.202204882openalex-snapshot
A Balance between Pro‐Inflammatory and Pro‐Reparative Macrophages is Observed in Regenerative D‐MAPS
inferredcites →https://doi.org/10.1002/biot.201700297openalex-snapshot
Macrophages of Different Phenotypes Influence the Migration of BMSCs in PLGA Scaffolds with Different Pore Size
inferredcites →https://doi.org/10.1002/btm2.10217openalex-snapshot
Mesenchymal stem cell‐inspired microgel scaffolds to control macrophage polarization
inferredcites →https://doi.org/10.1002/jbm.a.10509openalex-snapshot
Pore size in implanted polypropylene filters is critical for tissue organization
inferredcites →https://doi.org/10.1002/jbm.a.31221openalex-snapshot
Proteomic analysis and quantification of cytokines and chemokines from biomaterial surface‐adherent macrophages and foreign body giant cells
inferredcites →https://doi.org/10.1002/jbm.a.32595openalex-snapshot
Characterization of the in vitro macrophage response and in vivo host response to poly(ethylene glycol)‐based hydrogels
inferredcites →https://doi.org/10.1002/jbm.a.32893openalex-snapshot
Biomaterial topography alters healing in vivo and monocyte/macrophage activation in vitro
inferredcites →https://doi.org/10.1002/jbm.a.34104openalex-snapshot
Student award winner in the undergraduate category for the society of biomaterials 9th World Biomaterials Congress, Chengdu, China, June 1–5, 2012
inferredcites →https://doi.org/10.1002/jbm.a.37540openalex-snapshot
Single versus dual microgel species for forming guest‐host microporous annealed particle PEG‐MAL hydrogel
inferredcites →https://doi.org/10.1002/lary.28442openalex-snapshot
Development of a microporous annealed particle hydrogel for long‐term vocal fold augmentation
inferredcites →https://doi.org/10.1002/path.4104openalex-snapshot
The myofibroblast matrix: implications for tissue repair and fibrosis
inferredcites →https://doi.org/10.1002/smll.201903147openalex-snapshot
Enhanced In Vivo Delivery of Stem Cells using Microporous Annealed Particle Scaffolds
inferredcites →https://doi.org/10.1002/smll.202303466openalex-snapshot
Void Volume Fraction of Granular Scaffolds
inferredcites →https://doi.org/10.1002/term.3280openalex-snapshot
Monocytes contribute to a pro‐healing response in 40 μm diameter uniform‐pore, precision‐templated scaffolds
inferredcites →https://doi.org/10.1007/bf01002772openalex-snapshot
Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections
inferredcites →https://doi.org/10.1007/s00281-011-0244-1openalex-snapshot
Biocompatibility of implants: lymphocyte/macrophage interactions
inferredcites →https://doi.org/10.1007/s10439-013-0933-0openalex-snapshot
Porous Implants Modulate Healing and Induce Shifts in Local Macrophage Polarization in the Foreign Body Reaction
inferredcites →https://doi.org/10.1007/s12079-021-00605-7openalex-snapshot
The complexity of TGFβ/activin signaling in regeneration
inferredcites →https://doi.org/10.1016/0142-9612(84)90060-7openalex-snapshot
Biomaterial biocompatibility and the macrophage
inferredcites →https://doi.org/10.1016/j.actbio.2018.07.015openalex-snapshot
Cartilage tissue formation through assembly of microgels containing mesenchymal stem cells
inferredcites →https://doi.org/10.1016/j.actbio.2022.04.023openalex-snapshot
Granular PEG hydrogels mediate osteoporotic MSC clustering via N-cadherin influencing the pro-resorptive bias of their secretory profile
inferredcites →https://doi.org/10.1016/j.actbio.2023.05.007openalex-snapshot
Cells resident to precision templated 40-µm pore scaffolds generate small extracellular vesicles that affect CD4+ T cell phenotypes through regulatory TLR4 signaling
inferredcites →https://doi.org/10.1016/j.apmt.2019.100466openalex-snapshot
Pore size-mediated macrophage M1-to-M2 transition influences new vessel formation within the compartment of a scaffold
inferredcites →https://doi.org/10.1016/j.bioactmat.2020.05.004openalex-snapshot
Substrate stiffness modulates bone marrow-derived macrophage polarization through NF-κB signaling pathway
inferredcites →https://doi.org/10.1016/j.biomaterials.2012.05.053openalex-snapshot
The effect of nitric oxide surface flux on the foreign body response to subcutaneous implants
inferredcites →https://doi.org/10.1016/j.biomaterials.2014.03.078openalex-snapshot
The effect of thick fibers and large pores of electrospun poly(ε-caprolactone) vascular grafts on macrophage polarization and arterial regeneration
inferredcites →https://doi.org/10.1016/j.biomaterials.2018.10.040openalex-snapshot
Microfluidic-enabled bottom-up hydrogels from annealable naturally-derived protein microbeads
inferredcites →https://doi.org/10.1016/j.biomaterials.2019.119739openalex-snapshot
Substrate curvature as a cue to guide spatiotemporal cell and tissue organization
inferredcites →https://doi.org/10.1016/j.copbio.2018.11.001openalex-snapshot
Granular hydrogels: emergent properties of jammed hydrogel microparticles and their applications in tissue repair and regeneration
inferredcites →https://doi.org/10.1016/j.jconrel.2018.05.006openalex-snapshot
Accelerated wound healing by injectable star poly(ethylene glycol)-b-poly(propylene sulfide) scaffolds loaded with poorly water-soluble drugs
inferredcites →https://doi.org/10.1016/j.jdermsci.2008.08.012openalex-snapshot
The hairless mouse in skin research
inferredcites →https://doi.org/10.1016/j.smim.2007.11.004openalex-snapshot
Foreign body reaction to biomaterials
inferredcites →https://doi.org/10.1016/j.tibtech.2019.01.006openalex-snapshot
Overlooked? Underestimated? Effects of Substrate Curvature on Cell Behavior
inferredcites →https://doi.org/10.1021/acsami.7b18458openalex-snapshot
Immunomodulatory ECM-like Microspheres for Accelerated Bone Regeneration in Diabetes Mellitus
inferredcites →https://doi.org/10.1038/nmat4290openalex-snapshot
Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates
inferredcites →https://doi.org/10.1038/nmat4294openalex-snapshot
Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks
inferredcites →https://doi.org/10.1038/nprot.2014.024openalex-snapshot
FibrilTool, an ImageJ plug-in to quantify fibrillar structures in raw microscopy images
inferredcites →https://doi.org/10.1038/s41563-018-0190-6openalex-snapshot
Spatial confinement downsizes the inflammatory response of macrophages
inferredcites →https://doi.org/10.1038/s41563-020-00844-wopenalex-snapshot
Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing
inferredcites →https://doi.org/10.1038/s41578-019-0148-6openalex-snapshot
Hydrogel microparticles for biomedical applications
inferredcites →https://doi.org/10.1038/s41584-019-0324-5openalex-snapshot
Evasion of apoptosis by myofibroblasts: a hallmark of fibrotic diseases
inferredcites →https://doi.org/10.1038/s41596-021-00550-0openalex-snapshot
Analyzing high-dimensional cytometry data using FlowSOM
inferredcites →https://doi.org/10.1039/c5tb00807gopenalex-snapshot
Systematic evaluation of natural scaffolds in cutaneous wound healing
inferredcites →https://doi.org/10.1039/c8bm01286eopenalex-snapshot
Clickable PEG hydrogel microspheres as building blocks for 3D bioprinting
inferredcites →https://doi.org/10.1073/pnas.1006442107openalex-snapshot
Proangiogenic scaffolds as functional templates for cardiac tissue engineering
inferredcites →https://doi.org/10.1073/pnas.162124199openalex-snapshot
Biomaterial adherent macrophage apoptosis is increased by hydrophilic and anionic substrates in vivo
inferredcites →https://doi.org/10.1084/jem.20190103openalex-snapshot
Transforming growth factor–β in tissue fibrosis
inferredcites →https://doi.org/10.1088/1748-6041/6/1/015007openalex-snapshot
The effect of pore size on tissue ingrowth and neovascularization in porous bioceramics of controlled architecturein vivo
inferredcites →https://doi.org/10.1089/wound.2013.0485openalex-snapshot
Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring
inferredcites →https://doi.org/10.1089/wound.2016.0696openalex-snapshot
Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions
inferredcites →https://doi.org/10.1097/00002480-198804000-00005openalex-snapshot
Inflammatory Response to Implants
inferredcites →https://doi.org/10.1111/iep.12346openalex-snapshot
Experimental models and methods for cutaneous wound healing assessment
inferredcites →https://doi.org/10.1111/j.1067-1927.2004.12404.xopenalex-snapshot
Quantitative and reproducible murine model of excisional wound healing
inferredcites →https://doi.org/10.1158/1535-7163.mct-10-0207openalex-snapshot
Immune Competency of a Hairless Mouse Strain for Improved Preclinical Studies in Genetically Engineered Mice
inferredcites →https://doi.org/10.1159/000348446openalex-snapshot
‘The Ideal Mesh?'
inferredcites →https://doi.org/10.1186/s13578-021-00656-8openalex-snapshot
Differing susceptibility of C57BL/6J and DBA/2J mice—parents of the murine BXD family, to severe acute respiratory syndrome coronavirus infection
inferredcites →https://doi.org/10.1371/journal.pone.0198528openalex-snapshot
Absorbance summation: A novel approach for analyzing high-throughput ELISA data in the absence of a standard
inferredcites →https://doi.org/10.21203/rs.3.rs-1766378/v1openalex-snapshot
Void space and scaffold analysis of packed particles: applications in granular biomaterials
inferredcites →https://doi.org/10.3389/fimmu.2020.02187openalex-snapshot
Surfing on Membrane Waves: Microvilli, Curved Membranes, and Immune Signaling
inferredcites →https://doi.org/10.3389/fmolb.2021.773866openalex-snapshot
Arginase Signalling as a Key Player in Chronic Wound Pathophysiology and Healing
inferredcites →https://doi.org/10.3390/cells11111824openalex-snapshot
Immune Cell Plasticity in Inflammation: Insights into Description and Regulation of Immune Cell Phenotypes
inferredcites →https://doi.org/10.4103/2347-9264.158862openalex-snapshot
Assessment of the histological state of the healing wound

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Tetrazine Click Annealed Map Hydrogels as in Situ Forming Scaffolds to Regenerate Bone Defects
inferred← citeshttps://doi.org/10.1002/adfm.202417704openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/adfm.76498openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/adhm.202402905openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/adhm.202403583openalex-snapshot
3D Biofabrication of Microporous Hydrogels for Tissue Engineering
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inferred← citeshttps://doi.org/10.1002/adhm.202501400openalex-snapshot
Immunomodulatory Delivery Materials for Tissue Repair
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Practical Guide to the Design of Granular Hydrogels for Customizing Complex Cellular Microenvironments
inferred← citeshttps://doi.org/10.1002/adhm.202502451openalex-snapshot
Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration
inferred← citeshttps://doi.org/10.1002/adhm.202502462openalex-snapshot
Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses
inferred← citeshttps://doi.org/10.1002/adhm.202503483openalex-snapshot
Zwitterionic Microgel Scaffolds Support Matrix Accumulation by Regulating Protein Adsorption
inferred← citeshttps://doi.org/10.1002/adhm.71566openalex-snapshot
Engineering Tissue‐Relevant Collagen Bundle Architectures via Macromolecular Crowding
inferred← citeshttps://doi.org/10.1002/adhm.71572openalex-snapshot
MAP Crosslinker Chirality Regulates Macrophage Polarization Through MD‐2 Engagement and Enables Tunable Immunomodulation Through Novel Peptide Design
inferred← citeshttps://doi.org/10.1002/adma.202500650openalex-snapshot
In Situ Magnetoelectric Generation of miRNA Sponges and Wireless Electric Stimulus by Conductive Granular Scaffolds for Nerve Regeneration
inferred← citeshttps://doi.org/10.1002/adma.202512919openalex-snapshot
Skin Relevant Biomaterials from Wound Healing, Medical Aesthetics, Flexible Electronics to Artificial Intelligence and Beyond
inferred← citeshttps://doi.org/10.1002/agt2.464openalex-snapshot
Gelatin methacryloyl granular scaffolds for localized mRNA delivery
inferred← citeshttps://doi.org/10.1002/jbm.a.70132openalex-snapshot
Microgel‐Based Immunomodulatory Biomaterials for Regulating Macrophage Polarization
inferred← citeshttps://doi.org/10.1002/ppsc.202500163openalex-snapshot
Metrics for Studying the Porous Void Space of Packed Particles
inferred← citeshttps://doi.org/10.1002/smll.202405406openalex-snapshot
3D Printing Hierarchical Porous Nanofibrous Scaffold for Bone Regeneration
inferred← citeshttps://doi.org/10.1002/smll.74406openalex-snapshot
Multifunctional Microgels: From Material Design to Skin Wound Healing Applications
inferred← citeshttps://doi.org/10.1002/smll.75043openalex-snapshot
Reconciling Granular Hydrogel Microstructure and Mechanics via a Temporary Thermo‐Responsive and Cell‐Invadable Matrix
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Unraveling the molecular dynamics of wound healing: integrating spatially resolved lipidomics and temporally resolved proteomics
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Deoxygenated hydroxyapatite inhibits macrophage inflammation through fibronectin restricted adsorption
inferred← citeshttps://doi.org/10.1016/j.actbio.2025.02.020openalex-snapshot
Exploration of biomaterial-tissue integration in heterogeneous microporous annealed particle scaffolds in subcutaneous implants over 12 months
inferred← citeshttps://doi.org/10.1016/j.actbio.2025.09.051openalex-snapshot
Fabrication of granular decellularized extracellular matrix hydrogels for wound repair
inferred← citeshttps://doi.org/10.1016/j.actbio.2025.10.031openalex-snapshot
Mechanical maturation of human dermal fibroblast-laden microporous annealed particle scaffolds during long-term in vitro culture
inferred← citeshttps://doi.org/10.1016/j.actbio.2026.02.030openalex-snapshot
Design and tissue engineering applications of microporous annealed particle (MAP) scaffolds
inferred← citeshttps://doi.org/10.1016/j.arthro.2024.11.094openalex-snapshot
Growth Hormone–Releasing Peptide 2 May Be Associated With Decreased M1 Macrophage Production and Increased Histologic and Biomechanical Tendon‐Bone Healing Properties in a Rat Rotator Cuff Tear Model
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2024.04.011openalex-snapshot
Advances and applications of biomimetic biomaterials for endogenous skin regeneration
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2026.07.017openalex-snapshot
Mechano-immunomodulatory biomaterials: From immune mechanosensing to translational design
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2025.123192openalex-snapshot
Micropore structure engineering of injectable granular hydrogels via controlled liquid-liquid phase separation facilitates regenerative wound healing in mice and pigs
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2025.123667openalex-snapshot
Comparative proteomic analysis of skin wound healing responses to biomaterial treatments identifies key pathways which govern differential regenerative outcomes
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2026.124021openalex-snapshot
Granular aerogel scaffolds with engineered pore microarchitecture for rapid cell infiltration, tissue integration, and vascularization
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2026.124402openalex-snapshot
Physical continuity at biomaterial–ECM interfaces is associated with reduced fibroblast activation and NF-κB signaling
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2026.124433openalex-snapshot
Machine learning–guided design of cooperative multi-size hydrogel microspheres for osteoarthritis therapy
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Bredigite bioceramic-based barrier membrane promotes guided bone regeneration by orchestrating an immuno-modulatory and osteogenic microenvironment
inferred← citeshttps://doi.org/10.1016/j.cej.2025.163723openalex-snapshot
Fire ant-inspired bone repair breakthrough: Self-assembly strategy of microspheres driven by physical hydrogen bonding and hydrophobic interactions
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Tuning liganded nanocrack geometry for dynamic regulation of host macrophages
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IL-4/C1q activated astrocyte-derived extracellular vesicles promote stroke infarct recovery by recruiting peripheral leukocytes
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Chondroitin sulfate doped poly(3, 4-ethylenedioxythiophene) for implantable supercapacitor with high conductivity and anti-inflammatory efficacy
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inferred← citeshttps://doi.org/10.1016/j.matt.2025.102493openalex-snapshot
3D pore shape is predictable in randomly packed particle systems
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Nanoadjuvant-integrated organic biomaterials for immune engineering: Mechanisms, design strategies, and translational applications
inferred← citeshttps://doi.org/10.1016/j.tibtech.2023.09.007openalex-snapshot
Emerging granular hydrogel bioinks to improve biological function in bioprinted constructs
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inferred← citeshttps://doi.org/10.1021/acsabm.5c01879openalex-snapshot
Skin Substitutes: Ushering in a New Era of Transition from Traditional Dressings to Bioprinted Scaffolds
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Hollow Copper Sulfide Photothermal Nanodelivery Platform Boosts Angiogenesis of Diabetic Wound by Scavenging Reactive Oxygen Species
inferred← citeshttps://doi.org/10.1021/acsami.4c09204openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acsnano.4c10044openalex-snapshot
Granular Porous Nanofibrous Microspheres Enhance Cellular Infiltration for Diabetic Wound Healing
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Biomaterials with droplet microfluidics
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Hydrogels: a promising therapeutic platform for inflammatory skin diseases treatment
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Design, fabrication, and application of bioengineering vascular networks based on microfluidic strategies
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A customizable, low-cost 3D-printed device for live cell confinement imaging
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Nanoscale opportunities in extracellular matrix mimicry
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The effect of the physicochemical properties of hydrogels on chronic inflammation by macrophage polarization
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Bioorthogonally reinforced injectable granular hydrogels synergizing ECM mimicry with microporosity for skin tissue engineering
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Physical cues influence the construction of the osteoimmune microenvironment: focus on the hematoma period
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Bioactive granular hydrogels for infection control and immune microenvironment remodeling in wound regeneration
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Electrical aligned polyurethane nerve guidance conduit modulates macrophage polarization and facilitates immunoregulatory peripheral nerve regeneration
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Volumetric Bioprinting of Aqueous Two-Phase Emulsion Bioinks Enables High-Fidelity Macroporous Hydrogel Scaffolds for Volumetric Muscle Loss Repair
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Multifunctional microgel stent accelerates wound healing
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An Injectable, Self-Healing Hydrogel Based on G-Quadruplexes/Phenylboronic Acid Composites with Antibacterial Activity
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Advances and Challenges in Immune-Modulatory Biomaterials for Wound Healing Applications
inferred← citeshttps://doi.org/10.62347/wrgw4430openalex-snapshot
Microporous annealed particle hydrogels in cell culture, tissue regeneration, and emerging application in cancer immunotherapy
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MAP hydrogel promotes revascularization of human ovarian graft and integration with the hypothalamic-pituitary axis in a mouse model of primary ovarian insufficiency
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