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Gold‐Catalyzed Direct Intermolecular Coupling of Ketones, Secondary Amines, and Alkynes: A Facile and Versatile Access to Propargylic Amines Containing a Quaternary Carbon Center
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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A Three-Component Coupling Reaction of Aldehydes, Amines, and Alkynes
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Enantioselektive Synthese von Propargylaminen durch Kupfer-katalysierte Addition von Alkinen an Enamine
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A Three-Component Coupling Reaction of Aldehydes, Amines, and Alkynes
inferredcites →https://doi.org/10.1002/1521-3773(20020715)41:14<2535::aid-anie2535>3.0.co;2-mopenalex-snapshot
Enantioselective Synthesis of Propargylamines by Copper-Catalyzed Addition of Alkynes to Enamines
inferredcites →https://doi.org/10.1002/adsc.200606118openalex-snapshot
Diastereoselective Synthesis of α‐Oxyamines via Gold‐, Silver‐ and Copper‐Catalyzed, Three‐Component Couplings of α‐Oxyaldehydes, Alkynes, and Amines in Water
inferredcites →https://doi.org/10.1002/ange.200352081openalex-snapshot
Three‐Component Enantioselective Synthesis of Propargylamines through Zr‐Catalyzed Additions of Alkyl Zinc Reagents to Alkynylimines
inferredcites →https://doi.org/10.1002/ange.200460158openalex-snapshot
Direct Organocatalytic Enantioselective Mannich Reactions of Ketimines: An Approach to Optically Active Quaternary α‐Amino Acid Derivatives
inferredcites →https://doi.org/10.1002/ange.200800160openalex-snapshot
A Highly Efficient and Selective AuI‐Catalyzed Tandem Synthesis of Diversely Substituted Pyrrolo[1,2‐a]quinolines in Aqueous Media
inferredcites →https://doi.org/10.1002/anie.200352081openalex-snapshot
Three‐Component Enantioselective Synthesis of Propargylamines through Zr‐Catalyzed Additions of Alkyl Zinc Reagents to Alkynylimines
inferredcites →https://doi.org/10.1002/anie.200460158openalex-snapshot
Direct Organocatalytic Enantioselective Mannich Reactions of Ketimines: An Approach to Optically Active Quaternary α‐Amino Acid Derivatives
inferredcites →https://doi.org/10.1002/anie.200800160openalex-snapshot
A Highly Efficient and Selective Au I ‐Catalyzed Tandem Synthesis of Diversely Substituted Pyrrolo[1,2‐ a ]quinolines in Aqueous Media
inferredcites →https://doi.org/10.1002/ardp.19122500151openalex-snapshot
Ueber ein Kondensationsprodukt aus Formaldehyd, Ammoniak und Antipyrin
inferredcites →https://doi.org/10.1002/ardp.19172550217openalex-snapshot
Eine Synthese von β‐Ketonbasen
inferredcites →https://doi.org/10.1002/chin.200531066openalex-snapshot
An Efficient Synthesis of Propargylamines via C—H Activation Catalyzed by Copper(I) in Ionic Liquids.
inferredcites →https://doi.org/10.1016/j.tet.2007.07.105openalex-snapshot
Multi-component coupling synthesis of polycyclic pyrrole derivatives via Ir- and Rh-catalyzed cycloisomerizations with microwave heating
inferredcites →https://doi.org/10.1016/j.tet.2007.11.042openalex-snapshot
Double nitro-Mannich reaction utilizing in situ generated N-trimethylsilylaldimines: novel four-component one-pot synthesis of nitroimines
inferredcites →https://doi.org/10.1016/j.tet.2007.11.043openalex-snapshot
AgY zeolite as catalyst for the effective three-component synthesis of propargylamines
inferredcites →https://doi.org/10.1016/j.tetlet.2004.01.044openalex-snapshot
Three-component coupling of aldehyde, alkyne, and amine catalyzed by silver in ionic liquid
inferredcites →https://doi.org/10.1016/s0040-4020(00)00957-1openalex-snapshot
The Boronic Mannich Reaction in a Solid-Phase Approach
inferredcites →https://doi.org/10.1016/s0040-4039(00)96887-4openalex-snapshot
Simple 4-acetoxy-5,6-dihydropyridinium salts: New synthons for the preparation of functionalized piperidine systems
inferredcites →https://doi.org/10.1016/s0040-4039(03)01674-5openalex-snapshot
Lewis acid promoted alkynylation of imines with terminal alkynes: simple, mild and efficient preparation of propargylic amines
inferredcites →https://doi.org/10.1021/ar020066uopenalex-snapshot
N-tert-Butanesulfinyl Imines: Versatile Intermediates for the Asymmetric Synthesis of Amines
inferredcites →https://doi.org/10.1021/cr940474eopenalex-snapshot
Additions of Organometallic Reagents to CN Bonds: Reactivity and Selectivity
inferredcites →https://doi.org/10.1021/cr980414zopenalex-snapshot
Catalytic Enantioselective Addition to Imines
inferredcites →https://doi.org/10.1021/ja00165a097openalex-snapshot
Crystal and molecular structure of dynemicin A: a novel 1,5-diyn-3-ene antitumor antibiotic
inferredcites →https://doi.org/10.1021/ja0174231openalex-snapshot
The Proline-Catalyzed Direct Asymmetric Three-Component Mannich Reaction: Scope, Optimization, and Application to the Highly Enantioselective Synthesis of 1,2-Amino Alcohols
inferredcites →https://doi.org/10.1021/ja026007topenalex-snapshot
Enantioselective Direct-Addition of Terminal Alkynes to Imines Catalyzed by Copper(I)pybox Complex in Water and in Toluene
inferredcites →https://doi.org/10.1021/ja028782eopenalex-snapshot
A Direct Catalytic Asymmetric Mannich-type Reaction to syn-Amino Alcohols
inferredcites →https://doi.org/10.1021/ja0359299openalex-snapshot
A Highly Efficient Three-Component Coupling of Aldehyde, Alkyne, and Amines via C−H Activation Catalyzed by Gold in Water
inferredcites →https://doi.org/10.1021/ja048627vopenalex-snapshot
Synthesis of Tertiary Propargylamines by Sequential Reactions of in Situ Generated Thioiminium Salts with Organolithium and -magnesium Reagents
inferredcites →https://doi.org/10.1021/ja061510hopenalex-snapshot
Catalytic Enantioselective Allylation of Ketoimines
inferredcites →https://doi.org/10.1021/jo00088a004openalex-snapshot
Copper(I)-Catalyzed Amination of Propargyl Esters. Selective Synthesis of Propargylamines, 1-Alken-3-ylamines, and (Z)-Allylamines
inferredcites →https://doi.org/10.1021/jo00111a016openalex-snapshot
Lithium Alkoxides of Cinchona Alkaloids as Chiral Controllers for Enantioselective Acetylide Addition to Cyclic N-Acyl Ketimines
inferredcites →https://doi.org/10.1021/jo01064a058openalex-snapshot
The Synthesis and Anticholinergic Activity of Ester and Amide Derivatives of 2-Substituted Piperidines
inferredcites →https://doi.org/10.1021/jo01311a014openalex-snapshot
Preparation of a series of highly hindered secondary amines, including bis(triethylcarbinyl)amine
inferredcites →https://doi.org/10.1021/jo034205copenalex-snapshot
Stereoselective Barbier-Type Allylation Reaction of Trifluoromethyl Aldimines
inferredcites →https://doi.org/10.1021/ol0001517openalex-snapshot
Use of Optically Active Cyclic N,N-Dialkyl Aminals in Asymmetric Induction
inferredcites →https://doi.org/10.1021/ol017022qopenalex-snapshot
Direct Addition of TMS-acetylene to Aldimines Catalyzed by a Simple, Commercially Available Ir(I) Complex
inferredcites →https://doi.org/10.1021/ol034473xopenalex-snapshot
Initiator-Dependent Chemoselective Addition of THF Radical to Aldehyde and Aldimine and Its Application to a Three-Component Reaction
inferredcites →https://doi.org/10.1021/ol035781yopenalex-snapshot
The First Silver-Catalyzed Three-Component Coupling of Aldehyde, Alkyne, and Amine
inferredcites →https://doi.org/10.1021/ol036153jopenalex-snapshot
Direct Vinylogous Mannich-Type Reactions via Ring Opening and Rearrangement of Vinyloxiranes
inferredcites →https://doi.org/10.1021/ol036462+openalex-snapshot
Copper-Catalyzed Coupling of Imines, Acid Chlorides, and Alkynes: A Multicomponent Route to Propargylamides
inferredcites →https://doi.org/10.1021/ol049936topenalex-snapshot
Microwave-Promoted Three-Component Coupling of Aldehyde, Alkyne, and Amine via C−H Activation Catalyzed by Copper in Water
inferredcites →https://doi.org/10.1021/ol051575+openalex-snapshot
Phosphine-Triggered Complete Chemo-Switch: From Efficient Aldehyde−Alkyne−Amine Coupling to Efficient Aldehyde−Alkyne Coupling in Water
inferredcites →https://doi.org/10.1021/ol060498vopenalex-snapshot
Highly Efficient One-Pot Three-Component Mannich Reaction in Water Catalyzed by Heteropoly Acids
inferredcites →https://doi.org/10.1021/ol062031qopenalex-snapshot
Carboxylic Acid Catalyzed Three-Component Aza-Friedel−Crafts Reactions in Water for the Synthesis of 3-Substituted Indoles
inferredcites →https://doi.org/10.1021/ol0702674openalex-snapshot
Catalytic Asymmetric Three-Component Acyl-Strecker Reaction
inferredcites →https://doi.org/10.1021/ol1008312openalex-snapshot
Unprecedented Cu(I)-Catalyzed Microwave-Assisted Three-Component Coupling of a Ketone, an Alkyne, and a Primary Amine
inferredcites →https://doi.org/10.1039/b108851nopenalex-snapshot
Highly efficient Grignard-type imine additions via C–H activation in water and under solvent-free conditions
inferredcites →https://doi.org/10.1039/b414060eopenalex-snapshot
Organonitrile ligated silver complexes with perfluorinated weakly coordinating anions and their catalytic application for coupling reactions
inferredcites →https://doi.org/10.1039/b416268dopenalex-snapshot
An efficient synthesis of propargylamines via C–H activation catalyzed by copper( i ) in ionic liquids
inferredcites →https://doi.org/10.1039/b607986popenalex-snapshot
Direct addition of alkynes to imines and related CN electrophiles: A convenient access to propargylamines
inferredcites →https://doi.org/10.1039/b702287eopenalex-snapshot
The first Au-nanoparticles catalyzed green synthesis of propargylamines via a three-component coupling reaction of aldehyde, alkyne and amine
inferredcites →https://doi.org/10.1039/b917923bopenalex-snapshot
Impregnated copper on magnetite: an efficient and green catalyst for the multicomponent preparation of propargylamines under solvent free conditions
inferredcites →https://doi.org/10.1055/s-2001-13376openalex-snapshot
A Microwave-Enhanced, Solventless Mannich Condensation on CuI-Doped Alumina
inferredcites →https://doi.org/10.1073/pnas.0307150101openalex-snapshot
Cu(I)-catalyzed direct addition and asymmetric addition of terminal alkynes to imines
inferredcites →https://doi.org/10.1080/07328309008543871openalex-snapshot
A Stereocontrolled Synthesis of a Lincosamine Precursor.
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Probing the MAO Enzymes with a Novel Family of Quaternary Propargylamine Derivatives
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Metal‐Catalyzed Multicomponent Reactions
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Catalytic Nucleophilic Addition of Alkynes to Imines: The A 3 (Aldehyde–Alkyne–Amine) Coupling
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Copper‐Catalyzed Diversity‐Oriented Three‐ and Five‐ Component Synthesis of Mono‐ and Dipropargylic Amines via Coupling of Alkynes, α‐Amino Esters and Aldehydes
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A Unique Route to Tetrasubstituted Propargylic Amines by Catalytic Markovnikov Hydroamination–Alkynylation
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Manganese‐Catalyzed Multicomponent Synthesis of Tetrasubstituted Propargylamines: System Development and Theoretical Study
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Zinc Oxide Sensitized Graphene Quantum Dots “ZnO‐GQDs”: A Hybrid Concept to Study Charge Transfer and its Catalytic Applicability to Synthesize Tetrasubstituted Propargylamines
inferred← citeshttps://doi.org/10.1002/ange.201206674openalex-snapshot
Copper/Titanium Catalysis Forms Fully Substituted Carbon Centers from the Direct Coupling of Acyclic Ketones, Amines, and Alkynes
inferred← citeshttps://doi.org/10.1002/ange.201300021openalex-snapshot
Redox‐Neutral Copper(II) Carboxylate Catalyzed α‐Alkynylation of Amines
inferred← citeshttps://doi.org/10.1002/ange.201310280openalex-snapshot
Cyclisierung von Goldacetyliden: Synthese von Vinylsulfonaten über Vinylidengold‐Komplexe
inferred← citeshttps://doi.org/10.1002/ange.201400557openalex-snapshot
Chemoselective Amination of Propargylic C(sp3)H Bonds by Cobalt(II)‐Based Metalloradical Catalysis
inferred← citeshttps://doi.org/10.1002/ange.202215741openalex-snapshot
Cadmium‐Doped and Pincer Ligand‐Modified Gold Nanocluster for Catalytic KA 2 Reaction
inferred← citeshttps://doi.org/10.1002/anie.201206674openalex-snapshot
Copper/Titanium Catalysis Forms Fully Substituted Carbon Centers from the Direct Coupling of Acyclic Ketones, Amines, and Alkynes
inferred← citeshttps://doi.org/10.1002/anie.201300021openalex-snapshot
Redox‐Neutral Copper(II) Carboxylate Catalyzed α‐Alkynylation of Amines
inferred← citeshttps://doi.org/10.1002/anie.201310280openalex-snapshot
Cyclization of Gold Acetylides: Synthesis of Vinyl Sulfonates via Gold Vinylidene Complexes
inferred← citeshttps://doi.org/10.1002/anie.201400557openalex-snapshot
Chemoselective Amination of Propargylic C(sp3)H Bonds by Cobalt(II)‐Based Metalloradical Catalysis
inferred← citeshttps://doi.org/10.1002/anie.202215741openalex-snapshot
Cadmium‐Doped and Pincer Ligand‐Modified Gold Nanocluster for Catalytic KA 2 Reaction
inferred← citeshttps://doi.org/10.1002/aoc.5429openalex-snapshot
CuII@PAA/PVC mesoporous fibers: A hybrid wedding as a high‐performance versatile heterogeneous catalyst for A3, KA2, and decarboxylative A3 reactions
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Effective catalytic approach of NiTiO3 photosonocatalyst for the synthesis of indazolo[3,2‐b]quinazoline and its photophysical property
inferred← citeshttps://doi.org/10.1002/chem.201103404openalex-snapshot
Silver(I)‐Catalyzed Tandem 1,3‐Acyloxy Migration/Mannich‐type Addition/Elimination of the Sulfonyl Group of N‐Sulfonylhydrazone‐propargylic Esters to 5,6‐Dihydropyridazin‐4‐one Derivatives
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Dual Gold Catalysis: σ,π‐Propyne Acetylide and Hydroxyl‐Bridged Digold Complexes as Easy‐To‐Prepare and Easy‐To‐Handle Precatalysts
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Rh‐Catalyzed Direct Enantioselective Alkynylation of α‐Ketiminoesters
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Identifying a Highly Active Copper Catalyst for KA2 Reaction of Aromatic Ketones
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ChemInform Abstract: Gold‐Catalyzed Direct Intermolecular Coupling of Ketones, Secondary Amines, and Alkynes: A Facile and Versatile Access to Propargylic Amines Containing a Quaternary Carbon Center.
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Bipyridyl Functionalized NHC‐Sulfenyl, Selenenyl Cations; Potential Species for Alkylation Reactions and Ligands in Copper(I) Catalysis
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Correlating Structure and KA2 Catalytic Activity of ZnII Hydrazone Complexes
inferred← citeshttps://doi.org/10.1002/ejoc.201200090openalex-snapshot
Three‐Component Coupling of Aldehydes, Amines, and Alkynes Catalyzed by Oxidized Copper Nanoparticles on Titania
inferred← citeshttps://doi.org/10.1002/ejoc.201701567openalex-snapshot
Zinc(II)‐Catalyzed Synthesis of Propargylamines by Coupling Aldimines and Ketimines with Alkynes
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Nano‐Fe3O4@TiO2/Cu2O Core‐shell Composite: A Convenient Magnetic Separable Catalyst for A3 and KA2 Coupling
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KA 2 ‐Coupling Reaction Catalyzed by Semi‐Heterogeneous Magnetically Graphene Oxide Supported Copper Catalyst under Microwave Condition
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Silver‐Mediated Organic Transformations of Propargylamines to Enones, α‐Thioketones, and Isochromans
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TIBAL‐Assisted Copper‐Catalyzed Ketone‐Amine‐Alkyne (KA 2 ) Reaction for Preparation of α‐Tertiary Propargylamines in Mild Conditions
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Nano Ag-doped magnetic-Fe3O4@mesoporous TiO2 core–shell hollow spheres: synthesis and enhanced catalytic activity in A3 and KA2 coupling reactions
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.11504-5openalex-snapshot
Catalytic Asymmetric 1,2-Alkynylation☆
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Cu2O/nano-CuFe2O4: A novel and recyclable magnetic catalyst for three-component coupling of carbonyl compounds–alkynes–amines under solvent-free condition
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The Ketone-Amine-Alkyne (KA2) coupling reaction: Transition metal-catalyzed synthesis of quaternary propargylamines
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Cooperative N-heterocyclic carbene Au and amino catalysis for continuous synthesis of secondary propargylamines in a fiber supported hydrophilic microenvironment
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Some insights into the gold-catalysed A3-coupling reaction
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The KA2 coupling reaction under green, solventless, heterogeneous catalysis
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A novel and convenient copper-catalyzed three-component coupling of aldehydes, alkynes, and hydroxylamines leading to propargylamines
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Zinc-aluminum mixed oxide nanocomposites catalyzed KA2 coupling of ketone, amine, and an alkyne: An environmentally benign approach
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Carboxylated Chitosan Nanocrystals: A Synthetic Route and Application as Superior Support for Gold-Catalyzed Reactions
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Cycloaurated Phosphinothioic Amide Complex as a Precursor of Gold(I) Nanoparticles: Efficient Catalysts for A 3 Synthesis of Propargylamines under Solvent-Free Conditions
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Recent Progress on Catalytic Addition Reactions to N -Unsubstituted Imines
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Zn-Catalyzed Multicomponent KA2 Coupling: One-Pot Assembly of Propargylamines Bearing Tetrasubstituted Carbon Centers
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Cu(II)–Hydromagnesite Catalyzed Synthesis of Tetrasubstituted Propargylamines and Pyrrolo[1,2-a]quinolinesviaKA2, A3 Couplings and Their Decarboxylative Versions
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Mechanistic Studies and Expansion of the Substrate Scope of Direct Enantioselective Alkynylation of α-Ketiminoesters Catalyzed by Adaptable (Phebox)Rhodium(III) Complexes
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[Silver(I)(Pyridine-Containing Ligand)] Complexes As Unusual Catalysts for A3-Coupling Reactions
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Gold-Catalyzed Three-Component Annulation: Efficient Synthesis of Highly Functionalized Dihydropyrazoles from Alkynes, Hydrazines, and Aldehydes or Ketones
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Site-Specific Modification of Amino Acids and Peptides by Aldehyde–Alkyne–Amine Coupling under Ambient Aqueous Conditions
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Direct Catalytic Asymmetric Alkynylation of Ketoimines
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The Role of Gold Acetylides as a Selectivity Trigger and the Importance of gem-Diaurated Species in the Gold-Catalyzed Hydroarylating-Aromatization of Arene-Diynes
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Interaction of Gold Acetylides with Gold(I) or Silver(I) Cations
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Highly Diastereoselective Convergent Synthesis of Polycyclic Pyrroles with Consecutive Quaternary Stereocenters: Cascade Construction of Multiple C–C and C–Hetero Bonds
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Transition Metal-catalysed Nucleophilic Additions of Terminal Alkynes in Water: Development and Synthetic Utility
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Transition metal-catalyzed carbocyclization of nitrogen and oxygen-tethered 1,n-enynes and diynes: synthesis of five or six-membered heterocyclic compounds
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Copper(ii) catalysis provides cyclohexanone-derived propargylamines free of solvent or excess starting materials: sole by-product is water
inferred← citeshttps://doi.org/10.1039/c3cc45301dopenalex-snapshot
CuBr for KA2 reaction: en route to propargylic amines bearing a quaternary carbon center
inferred← citeshttps://doi.org/10.1039/c3nj01146aopenalex-snapshot
Nano copper( i ) oxide–zinc oxide catalyzed coupling of aldehydes or ketones, secondary amines, and terminal alkynes in solvent-free conditions
inferred← citeshttps://doi.org/10.1039/c4gc02318hopenalex-snapshot
Synthesis of tetrasubstituted propargylamines from cyclohexanone by solvent-free copper( ii ) catalysis
inferred← citeshttps://doi.org/10.1039/c4ra05190dopenalex-snapshot
Gold nanoparticle supported on ionic liquid-modified graphene oxide as an efficient and recyclable catalyst for one-pot oxidative A 3 -coupling reaction of benzyl alcohols
inferred← citeshttps://doi.org/10.1039/c5nj03272eopenalex-snapshot
Polystyrene supported N-phenylpiperazine–Cu( ii ) complex: an efficient and reusable catalyst for KA 2 -coupling reactions under solvent-free conditions
inferred← citeshttps://doi.org/10.1039/c5sc02933copenalex-snapshot
Gold-catalyzed tandem reactions of amide–aldehyde–alkyne coupling and cyclization-synthesis of 2,4,5-trisubstituted oxazoles
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Solvent-free synthesis of propargylamines: an overview
inferred← citeshttps://doi.org/10.1039/d3qo00272aopenalex-snapshot
Gold-catalyzed multicomponent reactions
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Structural regulation of CuOx/CeO2 and its application in α-tert-propylamine synthesis
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Thioamides and Thioformamides for Sequential Reactions with Organolithium and Grignard Reagents
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Catalysts For Propargylamines Synthesis Via A3, AHA, and KA2 Coupling - A Review
inferred← citeshttps://doi.org/10.26434/chemrxiv.11691852openalex-snapshot
Carboxylated Chitosan Nanocrystals: Novel Synthetic Route and Application as Superior Support for Gold-Catalyzed Reactions
inferred← citeshttps://doi.org/10.26434/chemrxiv.11691852.v1openalex-snapshot
Carboxylated Chitosan Nanocrystals: Novel Synthetic Route and Application as Superior Support for Gold-Catalyzed Reactions
inferred← citeshttps://doi.org/10.3390/molecules23112975openalex-snapshot
Immobilized Gold Nanoparticles Prepared from Gold(III)-Containing Ionic Liquids on Silica: Application to the Sustainable Synthesis of Propargylamines
inferred← citeshttps://doi.org/10.3390/molecules25184043openalex-snapshot
Synthesis, Characterization, Catalytic Activity, and DFT Calculations of Zn(II) Hydrazone Complexes
inferred← citeshttps://doi.org/10.3390/molecules29112486openalex-snapshot
Are Terminal Alkynes Necessary for MAO-A/MAO-B Inhibition? A New Scaffold Is Revealed
inferred← citeshttps://doi.org/10.3762/bjoc.10.46openalex-snapshot
Silver and gold-catalyzed multicomponent reactions
inferred← citeshttps://doi.org/10.3762/bjoc.11.154openalex-snapshot
Synthesis of alpha-tetrasubstituted triazoles by copper-catalyzed silyl deprotection/azide cycloaddition
inferred← citeshttps://doi.org/10.3762/bjoc.16.23openalex-snapshot
Combination of multicomponent KA2 and Pauson–Khand reactions: short synthesis of spirocyclic pyrrolocyclopentenones
inferred← citeshttps://doi.org/10.70675/656eb804ze63bz48a6z84b3z2178c6efbcbfopenalex-snapshot
(Bi)metallic nanoparticles in glycerol : synthesis, characterization and catalytic aplications
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