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Herstellung enantiomerenreiner cis‐ oder trans‐konfigurierter 2‐(tert‐Butyl)‐3‐methylimidazolidin‐4‐one aus den Aminosäuren (S)‐Alanin, (S)‐Phenylalanin, (R)‐Phenylglycin, (S)‐Methionin und (S)‐Valin
Delineation of structural domains involved in the subtype specificity of tachykinin receptors through chimeric formation of substance P/substance K receptors.
Synthesis of Nonproteinogenic (R)‐ or (S)‐Amino Acids Analogues of Phenylalanine, Isotopically Labelled and Cyclic Amino Acids from tert‐Butyl 2‐(tert‐Butyl)‐3‐methyl‐4‐oxo‐1‐imidazolidinecarboxylate (Boc‐BMI)
Macrocyclic peptides, 4. Preparations and enantioface‐differentiating abilities of 27‐ and 36‐membered ring peptides containing N,N′‐ethylene‐bridged dipeptides and glycine
Bombesin, vasopressin, and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. Identification of a novel tyrosine kinase as a major substrate.
Design of bioactive peptides based on antibody hypervariable region structures. Development of conformationally constrained and dimeric peptides with enhanced affinity.
A new approach to receptor ligand design: synthesis and conformation of a new class of potent and highly selective μ opioid antagonists utilizing tetrahydroisoouinoline carroxylic acid
A convenient preparation of derivatives of 3(s)-amino-10(r)-carboxy-1,6-diaza-cyclodeca-2,7-dione the dilactam of L-α, γ-diaminobutyric acid and d-glutamic acid: A β-turn template
Asymmetric synthesis of topographically constrained amino acids: synthesis of the optically pure isomers of α,β-dimethyl-phenylalanine and α,β-dimethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Micelle-bound conformations of a bombesin/gastrin releasing peptide receptor agonist and an antagonist by two-dimensional NMR and restrained molecular dynamics
IUPAC-IUB Commission on Biochemical Nomenclature. Abbreviations and symbols for the description of the conformation of polypeptide chains. Tentative rules (1969)
Nonpeptidal peptidomimetics with .beta.-D-glucose scaffolding. A partial somatostatin agonist bearing a close structural relationship to a potent, selective substance P antagonist
The first design and synthesis of a steroidal peptidomimetic. The potential value of peptidomimetics in elucidating the bioactive conformation of peptide ligands
Rationally designed "dipeptoid" analogs of CCK. .alpha.-Methyltryptophan derivatives as highly selective and orally active gastrin and CCK-B antagonists with potent anxiolytic properties
trans-3-n-propyl-L-proline is a highly favorable, conformationally restricted replacement for methionine in the C-terminal tetrapeptide of cholecystokinin. Stereoselective synthesis of 3-allyl- and 3-n-propyl-L-proline derivatives from 4-hydroxy-L-proline
Synthesis and structure-activity relationships of a novel series of non-peptide angiotensin II receptor binding inhibitors specific for the AT2 subtype
Design and synthesis of somatostatin analogs with topographical properties that lead to highly potent and specific .mu. opioid receptor antagonists with greatly reduced binding at somatostatin receptors
Topographic probes of angiotensin and receptor: potent angiotensin II agonist containing diphenylalanine and long-acting antagonists containing biphenylalanine and 2-indan amino acid in position 8
Synthesis of .alpha.-benzyl .gamma.-lactam, .alpha.-benzyl .delta.-lactam, and .alpha.-benzylproline derivatives as conformationally restricted analogs of phenylalaninamide
Conformationally restricted cyclic nonapeptides derived from L-cysteine and LL-3-amino-2-piperidone-6-carboxylic acid (LL-Acp), a potent .beta.-turn-inducing dipeptide analog
Design, synthesis, and conformational analysis of azacycloalkane amino acids as conformationally constrained probes for mimicry of peptide secondary structures
Bicyclic Compounds Derived from Tartaric Acid and α-Amino Acids (BTAas): Synthesis of New Molecular Scaffolds Derived from the Combination of (R,R)-Tartaric Acid andL-Serine
Mild and High‐Yielding Molybdenum(VI) Dichloride Dioxide‐Catalyzed Formation of Mono‐, Di‐, Tri‐, and Tetracarbamates from Alcohols and Aromatic or Aliphatic Isocyanates
Synthesis, conformational analysis, and spectroscopic characterization of peptides based on Daf, the first rigid transition‐metal receptor, cyclic Cα,α‐disubstituted glycine
Organocatalyzed Asymmetric 1,4‐Addition of Azlactones to α,β‐Unsaturated Trichloromethyl Ketones: Synthesis of α,α‐Disubstituted α‐Amino Acid Derivatives
Global chain properties of an all l ‐α‐eicosapeptide with a secondary α‐helix and its all retro d ‐inverso‐α‐eicosapeptide estimated through the modeling of their CZE ‐determined electrophoretic mobilities
Optically Active 5‐(Hydroxyalkyl)‐ and 5‐(Aminoalkyl)pyrazolidin‐3‐ones by Ring‐Chain Transformation of α,β‐Unsaturated Lactones or Lactams with Hydrazines
Transition state isosteres of the γ‐glutamyl peptide bond hydrolysis: synthesis and characterization of the ψ[CH2NH] pseudopeptide analogue of glutathione
Introduction to Mid-size Drugs and Peptidomimetics
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