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ROS/RNS and Base Dual Activatable Merocyanine‐Based NIR‐II Fluorescent Molecular Probe for in vivo Biosensing

https://doi.org/10.1002/anie.202109728
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Near‐Infrared‐II Molecular Dyes for Cancer Imaging and Surgery
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inferredcites →https://doi.org/10.1002/ange.202007040openalex-snapshot
Molecular Engineering of NIR‐II Fluorophores for Improved Biomedical Detection
inferredcites →https://doi.org/10.1002/ange.202012021openalex-snapshot
NIR‐II pH Sensor with a FRET Adjustable Transition Point for In Situ Dynamic Tumor Microenvironment Visualization
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inferredcites →https://doi.org/10.1002/ange.202014638openalex-snapshot
Assembly of α‐(Hetero)aryl Nitriles via Copper‐Catalyzed Coupling Reactions with (Hetero)aryl Chlorides and Bromides
inferredcites →https://doi.org/10.1002/anie.201500088openalex-snapshot
Self‐Immolative Spacers: Kinetic Aspects, Structure–Property Relationships, and Applications
inferredcites →https://doi.org/10.1002/anie.201801226openalex-snapshot
An Efficient 1064 nm NIR‐II Excitation Fluorescent Molecular Dye for Deep‐Tissue High‐Resolution Dynamic Bioimaging
inferredcites →https://doi.org/10.1002/anie.201904182openalex-snapshot
Stable, Wavelength‐Tunable Fluorescent Dyes in the NIR‐II Region for In Vivo High‐Contrast Bioimaging and Multiplexed Biosensing
inferredcites →https://doi.org/10.1002/anie.202007040openalex-snapshot
Molecular Engineering of NIR‐II Fluorophores for Improved Biomedical Detection
inferredcites →https://doi.org/10.1002/anie.202012021openalex-snapshot
NIR‐II pH Sensor with a FRET Adjustable Transition Point for In Situ Dynamic Tumor Microenvironment Visualization
inferredcites →https://doi.org/10.1002/anie.202012427openalex-snapshot
Bright and Stable NIR‐II J‐Aggregated AIE Dibodipy‐Based Fluorescent Probe for Dynamic In Vivo Bioimaging
inferredcites →https://doi.org/10.1002/anie.202103071openalex-snapshot
A Promising NIR‐II Fluorescent Sensor for Peptide‐Mediated Long‐Term Monitoring of Kidney Dysfunction
inferredcites →https://doi.org/10.1007/s00240-011-0389-3openalex-snapshot
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Halogen Effects-Induced Bright D−π–A Fluorophore as Scaffold for NIR Fluorogenic Probes with High Contrast
inferredcites →https://doi.org/10.1021/acs.analchem.9b03152openalex-snapshot
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inferredcites →https://doi.org/10.1021/jacs.1c03004openalex-snapshot
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inferredcites →https://doi.org/10.1021/jo300400qopenalex-snapshot
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inferredcites →https://doi.org/10.1021/jo9706178openalex-snapshot
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inferredcites →https://doi.org/10.1038/nmat3819openalex-snapshot
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inferredcites →https://doi.org/10.1038/nmat4476openalex-snapshot
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inferredcites →https://doi.org/10.1038/nrd2222openalex-snapshot
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inferredcites →https://doi.org/10.1038/s41467-019-09043-xopenalex-snapshot
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inferredcites →https://doi.org/10.1038/s41557-020-0426-3openalex-snapshot
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inferredcites →https://doi.org/10.1039/c6cs00192kopenalex-snapshot
Recent progress in the development of fluorescent, luminescent and colorimetric probes for detection of reactive oxygen and nitrogen species
inferredcites →https://doi.org/10.1039/c8cs00234gopenalex-snapshot
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inferredcites →https://doi.org/10.1039/c9sc03504dopenalex-snapshot
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inferredcites →https://doi.org/10.1073/pnas.1701976114openalex-snapshot
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inferredcites →https://doi.org/10.1080/01635589009514091openalex-snapshot
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inferredcites →https://doi.org/10.1089/ars.2012.5149openalex-snapshot
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inferredcites →https://doi.org/10.1097/01.mib.0000195385.19268.68openalex-snapshot
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inferredcites →https://doi.org/10.1136/gut.48.4.526openalex-snapshot
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inferredcites →https://doi.org/10.1136/gut.48.4.571openalex-snapshot
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inferredcites →https://doi.org/10.1177/014107688507800311openalex-snapshot
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inferredcites →https://doi.org/10.12688/f1000research.16096.1openalex-snapshot
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inferredcites →https://doi.org/10.3390/biomedicines9020152openalex-snapshot
Molecular Imaging of Inflammatory Disease
inferredcites →https://doi.org/10.5009/gnl14226openalex-snapshot
Current and Emerging Biologics for Ulcerative Colitis

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Observation of diagnostic and therapeutic processes of inflammation and ferroptosis by a three-channel fluorescent probe
inferred← citeshttps://doi.org/10.1016/j.snb.2025.137835openalex-snapshot
Hypoxia and viscosity Co-controlled fluorescence probe for signal amplification imaging of early hypoxia-related diseases
inferred← citeshttps://doi.org/10.1016/j.snb.2026.139557openalex-snapshot
An acetylcholinesterase-activated near-infrared frequency upconversion luminescence probe for real-time imaging of oxidative stress-regulated acetylcholinesterase dynamics
inferred← citeshttps://doi.org/10.1016/j.snb.2026.140416openalex-snapshot
H2O2-triggered in situ generation of near-infrared fluorophore for ulcerative colitis imaging diagnosis
inferred← citeshttps://doi.org/10.1016/j.snr.2025.100305openalex-snapshot
Dual-mode ratiometric electrochemical and turn-on fluorescent probe for reliably detecting H2O2 in Parkinson's disease serum
inferred← citeshttps://doi.org/10.1016/j.talanta.2023.125264openalex-snapshot
Recent progress of near-infrared fluorescent probes in the determination of reactive oxygen species for disease diagnosis
inferred← citeshttps://doi.org/10.1016/j.talanta.2025.127928openalex-snapshot
An activatable β-diketonate europium(III) complex-based probe for time-gated luminescence detection and imaging of peroxynitrite in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.trac.2023.117360openalex-snapshot
In vivo optical imaging of reactive oxygen species (ROS)-related non-cancerous diseases
inferred← citeshttps://doi.org/10.1016/j.trac.2025.118409openalex-snapshot
Tailored NIR-II luminescence probes for in situ capture of spatiotemporal physiological information in living organisms
inferred← citeshttps://doi.org/10.1016/j.trac.2026.118780openalex-snapshot
Near-infrared II chalcogenonium salt chromophores: Recent advances in imaging, biosensing, and therapeutic applications
inferred← citeshttps://doi.org/10.1021/acs.accounts.3c00495openalex-snapshot
Ratiometric Optical and Photoacoustic Imaging In Vivo in the Second Near-Infrared Window
inferred← citeshttps://doi.org/10.1021/acs.analchem.1c05447openalex-snapshot
A New Ratiometric Design Strategy Based on Modulation of π-Conjugation Unit for Developing Fluorescent Probe and Imaging of Cellular Peroxynitrite
inferred← citeshttps://doi.org/10.1021/acs.analchem.2c00415openalex-snapshot
An Intramolecular Charge Transfer–Förster Resonance Energy Transfer Integrated Unimolecular Platform for Two-Photon Ratiometric Fluorescence Sensing of Methionine Sulfoxide Reductases in Live-Neurons and Mouse Brain Tissues
inferred← citeshttps://doi.org/10.1021/acs.analchem.2c01241openalex-snapshot
Aminopeptidase N Activatable Nanoprobe for Tracking Lymphatic Metastasis and Guiding Tumor Resection Surgery via Optoacoustic/NIR-II Fluorescence Dual-Mode Imaging
inferred← citeshttps://doi.org/10.1021/acs.analchem.2c02052openalex-snapshot
H 2 O 2 -Activated NIR-II Fluorescent Probe with a Large Stokes Shift for High-Contrast Imaging in Drug-Induced Liver Injury Mice
inferred← citeshttps://doi.org/10.1021/acs.analchem.2c03404openalex-snapshot
Water-Dispersible Activatable Nanoprobe for Detecting Cadmium-Ion-Induced Oxidative Stress in Edible Crops via Near-Infrared Second-Window Fluorescence Imaging
inferred← citeshttps://doi.org/10.1021/acs.analchem.2c04175openalex-snapshot
pH-Switched Near-Infrared Fluorescent Strategy for Ratiometric Detection of ONOO– in Lysosomes and Precise Imaging of Oxidative Stress in Rheumatoid Arthritis
inferred← citeshttps://doi.org/10.1021/acs.analchem.2c04640openalex-snapshot
Rationally Constructed De Novo Fluorescent Nanosensor for Nitric Oxide Detection and Imaging in Living Cells and Inflammatory Mice Models
inferred← citeshttps://doi.org/10.1021/acs.analchem.2c05422openalex-snapshot
A Reaction-Based Ratiometric Bioluminescent Platform for Point-of-Care and Quantitative Detection Using a Smartphone
inferred← citeshttps://doi.org/10.1021/acs.analchem.4c00665openalex-snapshot
Tri-mode Responses to Reactive Oxygen Species In Vivo by Chiral Vanadium-Based Nanoparticles
inferred← citeshttps://doi.org/10.1021/acs.analchem.4c03685openalex-snapshot
A Cascade Activation Probe with Double-Enhanced Near-Infrared Imaging for Monitoring Peroxynitrite Fluctuations in Vivo
inferred← citeshttps://doi.org/10.1021/acs.analchem.4c03889openalex-snapshot
Near-Infrared Unimolecular Chemiluminescence Probes for Deep-Tissue Imaging
inferred← citeshttps://doi.org/10.1021/acs.analchem.4c06622openalex-snapshot
Mercury(II)-Triggered Targeted and NIR-II Fluorescence/Photoacoustic Imaging Probe for High-Sensitivity Early Diagnosis and Evaluating Drug against Acute Liver and Kidney Injury
inferred← citeshttps://doi.org/10.1021/acs.analchem.5c00538openalex-snapshot
A Novel Adamantane-Dioxetane-Based Chemiluminescent Probe for Highly Selective and Sensitive Bioimaging of Hydrogen Peroxide In Vitro and In Vivo
inferred← citeshttps://doi.org/10.1021/acs.analchem.5c05358openalex-snapshot
A Turn-On Fluorescent and Ratiometric Electrochemical Dual-Mode Probe for Hydrogen Peroxide Detection in Brain Microdialysates of Alzheimer’s Disease Mice
inferred← citeshttps://doi.org/10.1021/acs.analchem.5c06231openalex-snapshot
H 2 O 2 -Responsive Organochalcogen-Based Probes for 19 F Chemical Shift-Switching MRI
inferred← citeshttps://doi.org/10.1021/acs.analchem.5c07889openalex-snapshot
Harnessing X-ray-Induced NIR-II Afterglow through ROS-Mediated Molecular Activation for Tumor Radiotheranostics
inferred← citeshttps://doi.org/10.1021/acs.analchem.6c00318openalex-snapshot
Profiling of Single Cells on a Droplet Microfluidics–SERS Platform for Multiplexed Analysis of Oxidative and Inflammatory Stress
inferred← citeshttps://doi.org/10.1021/acs.analchem.6c01482openalex-snapshot
Rapid Visual Detection of Phoxim Via Competitive Binding in a Flavonoid-Based Fluorescent Dye@Whey Protein Sensor
inferred← citeshttps://doi.org/10.1021/acs.analchem.6c03226openalex-snapshot
H 2 O 2 /Viscosity Tandem-Locked Fluorescent Probes Based on an In Situ Fluorophore Synthesis Strategy for Colitis Imaging and Diagnosis
inferred← citeshttps://doi.org/10.1021/acs.analchem.6c04759openalex-snapshot
A Versatile Aza-BODIPY-Based Activatable Probe for High-Contrast NIR-II Biosensing
inferred← citeshttps://doi.org/10.1021/acs.chemmater.2c01024openalex-snapshot
Self-Immolative Polymer-Based Chemiluminescent Nanoparticles for Long-Term In Vivo Imaging of Reactive Oxygen Species
inferred← citeshttps://doi.org/10.1021/acs.chemrev.3c00892openalex-snapshot
Ex Tenebris Lux: Illuminating Reactive Oxygen and Nitrogen Species with Small Molecule Probes
inferred← citeshttps://doi.org/10.1021/acs.nanolett.3c00983openalex-snapshot
Molecular-Based FRET Nanosensor with Dynamic Ratiometric NIR-IIb Fluorescence for Real-Time In Vivo Imaging and Sensing
inferred← citeshttps://doi.org/10.1021/acs.nanolett.4c01364openalex-snapshot
A Dual-Cascade Activatable Near-Infrared Fluorescent Probe for Precise Intraoperative Imaging of Tumor
inferred← citeshttps://doi.org/10.1021/acsami.2c11662openalex-snapshot
Morpholine-Functionalized Multicomponent Metallacage as a Vector for Lysosome-Targeted Cell Imaging
inferred← citeshttps://doi.org/10.1021/acsami.4c14291openalex-snapshot
Multifunctional MnGA Nanozymes for the Treatment of Ulcerative Colitis by Reducing Intestinal Inflammation and Regulating the Intestinal Flora
inferred← citeshttps://doi.org/10.1021/acsami.6c05339openalex-snapshot
Near Infrared Dyes Based on Diradicaloids: Molecular Design, Photophysical Properties and Bioapplications
inferred← citeshttps://doi.org/10.1021/acsmaterialslett.2c00451openalex-snapshot
“Crossbreeding” Small-Molecular Weight NIR-II Flavchromenes Endows Activatable Multiplexed In Vivo Imaging
inferred← citeshttps://doi.org/10.1021/acssensors.1c02684openalex-snapshot
Selective, Rapid, and Ratiometric Fluorescence Sensing of Homocysteine in Live Neurons via a Reaction-Kinetics/Sequence-Differentiation Strategy Based on a Small Molecular Probe
inferred← citeshttps://doi.org/10.1021/acssensors.3c02420openalex-snapshot
Thioketal-Based Electrochemical Sensor Reveals Biphasic Effects of l -DOPA on Neuroinflammation
inferred← citeshttps://doi.org/10.1021/cbmi.4c00024openalex-snapshot
Recent Progress in Molecular Probes for Imaging of Acute Kidney Injury
inferred← citeshttps://doi.org/10.1021/cbmi.5c00005openalex-snapshot
Albumin Encapsulation of Cyanine Dye for High-Performance NIR-II Imaging-Guided Photodynamic Therapy
inferred← citeshttps://doi.org/10.1021/jacs.2c05826openalex-snapshot
Stable, Bright, and Long-Fluorescence-Lifetime Dyes for Deep-Near-Infrared Bioimaging
inferred← citeshttps://doi.org/10.1021/jacs.2c10041openalex-snapshot
Polymethine Molecular Platform for Ratiometric Fluorescent Probes in the Second near-Infrared Window
inferred← citeshttps://doi.org/10.1021/jacs.2c13218openalex-snapshot
Highly Sensitive Imaging of Tumor Metastasis Based on the Targeting and Polarization of M2-like Macrophages
inferred← citeshttps://doi.org/10.1021/jacs.5c06682openalex-snapshot
Shortwave Infrared Hemicyanine-6 for Cancer-Activated and Shaving-Free Preclinical Imaging of Lung Metastasis
inferred← citeshttps://doi.org/10.1021/jacs.5c13688openalex-snapshot
Electronic-Symmetry-Tuned Emission Beyond 1500 nm in Erbium(III)-Phthalocyanine Complexes for High-Resolution In Vivo Biosensing
inferred← citeshttps://doi.org/10.1038/s41377-026-02212-wopenalex-snapshot
Organic small-molecule NIR-II fluorophores for tumor phototheranostics
inferred← citeshttps://doi.org/10.1038/s44222-022-00002-8openalex-snapshot
Near-infrared luminescence high-contrast in vivo biomedical imaging
inferred← citeshttps://doi.org/10.1039/d2an00163bopenalex-snapshot
Sensitive sensing of alkaline phosphatase and γ-glutamyltranspeptidase activity for tumor imaging
inferred← citeshttps://doi.org/10.1039/d2cc07008aopenalex-snapshot
Multi-stimuli-responsive molecular fluorescent probes for bioapplications
inferred← citeshttps://doi.org/10.1039/d2cs00172aopenalex-snapshot
Recent progress in the development of fluorescent probes for imaging pathological oxidative stress
inferred← citeshttps://doi.org/10.1039/d2qm01120dopenalex-snapshot
Recent advances in activatable NIR-II organic fluorophores for biomedical applications
inferred← citeshttps://doi.org/10.1039/d2sc03136aopenalex-snapshot
The pursuit of polymethine fluorophores with NIR-II emission and high brightness for in vivo applications
inferred← citeshttps://doi.org/10.1039/d2tc03532dopenalex-snapshot
Starch-based near-infrared organic fluorophores for the imaging of latent fingerprints
inferred← citeshttps://doi.org/10.1039/d4cc03512gopenalex-snapshot
A novel NIR-II fluorescent probe for hydrogen peroxide detection in drug-induced liver injury
inferred← citeshttps://doi.org/10.1039/d4sc08228aopenalex-snapshot
Logic-gated approach for targeted delivery and site-selective activation of photothermal agents in precision cancer treatment
inferred← citeshttps://doi.org/10.1039/d4tb01867bopenalex-snapshot
Frontiers in fluorescence imaging: tools for the in situ sensing of disease biomarkers
inferred← citeshttps://doi.org/10.1039/d4tb02480jopenalex-snapshot
Xanthene-based NIR organic phototheranostics agents: design strategies and biomedical applications
inferred← citeshttps://doi.org/10.1039/d5cs00063gopenalex-snapshot
Construction and optimization of organic fluorophores in NIR-II fluorescence imaging
inferred← citeshttps://doi.org/10.1039/d5cs00502gopenalex-snapshot
Single- and multi-modal molecular probes with second near-infrared activatable optical signals for disease diagnosis and theranostics
inferred← citeshttps://doi.org/10.1039/d5cs01412copenalex-snapshot
Optical probes for bioimaging of tumor-infiltrating immune cells and their applications in cancer immunotherapy
inferred← citeshttps://doi.org/10.1039/d5sc02705eopenalex-snapshot
A dual-excitation ratiometric NIR-II fluorescent nanoplatform enables high contrast in vivo imaging
inferred← citeshttps://doi.org/10.1039/d5sc08871bopenalex-snapshot
Zero-trigger ultrafast charge-transfer J-aggregates via Se/π-directed assembly enable synchronous ROS/heat amplification for NIR-II photoimmunotherapy
inferred← citeshttps://doi.org/10.1039/d6cc03027kopenalex-snapshot
A facile sequentially-activatable fluorescent probe for fast imaging of the superoxide anion in ulcerative colitis
inferred← citeshttps://doi.org/10.1039/d6cc04618eopenalex-snapshot
A H 2 S-activatable NIR-II aza-BODIPY probe for early detection of drug-induced liver injury
inferred← citeshttps://doi.org/10.1039/d6tb00992aopenalex-snapshot
A superoxide anion-specific chemiluminescent probe for detection of acute inflammation
inferred← citeshttps://doi.org/10.1055/a-2033-8557openalex-snapshot
New High-Performance Fluorescent Dye Scaffolds: Applications for Bioimaging and Biosensing
inferred← citeshttps://doi.org/10.1055/a-2071-4549openalex-snapshot
Near-Infrared Hemicyanine Fluorophores with Optically Tunable Groups: A ‘Leap Forward’ for in Vivo Sensing and Imaging
inferred← citeshttps://doi.org/10.1080/10408347.2022.2080495openalex-snapshot
Application of Fluorescent Probes in Reactive Oxygen Species Disease Model
inferred← citeshttps://doi.org/10.3389/fchem.2022.1054913openalex-snapshot
Recent advances in NIR-II fluorescence based theranostic approaches for glioma
inferred← citeshttps://doi.org/10.3390/bios12080646openalex-snapshot
Reactive Species-Activatable AIEgens for Biomedical Applications
inferred← citeshttps://doi.org/10.3390/chemosensors10010019openalex-snapshot
Rational Design and Synthesis of Large Stokes Shift 2,6-Sulphur-Disubstituted BODIPYs for Cell Imaging
inferred← citeshttps://doi.org/10.3390/ijms23115936openalex-snapshot
Chemical Probes and Activity-Based Protein Profiling for Cancer Research
inferred← citeshttps://doi.org/10.3390/ijms24010188openalex-snapshot
Near-Infrared Dyes: Towards Broad-Spectrum Antivirals
inferred← citeshttps://doi.org/10.34133/research.0075openalex-snapshot
Rational Design of Organelle-Targeted Fluorescent Probes: Insights from Artificial Intelligence
inferred← citeshttps://doi.org/10.3788/cjl231338openalex-snapshot
近红外二区花菁染料在疾病应用中的研究进展
inferred← citeshttps://doi.org/10.3788/cjl231341openalex-snapshot
近红外二区荧光金纳米团簇用于生物医学光子学：进展与挑战
inferred← citeshttps://doi.org/10.5772/intechopen.112303openalex-snapshot
Oxidative Stress and Reproduction Health: Physiology, Pathology, and Clinical Biomarkers
inferred← citeshttps://doi.org/10.7150/thno.71359openalex-snapshot
Activatable NIR-II organic fluorescent probes for bioimaging
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