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Why is it crucial to reintegrate pathology into cancer research?

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/jama.300.13.1580openalex-snapshot
The Conflict Between Complex Systems and Reductionism
inferredcites →https://doi.org/10.1002/cncr.22966openalex-snapshot
Getting to personalized cancer medicine
inferredcites →https://doi.org/10.1002/cncr.24353openalex-snapshot
Systems pathology
inferredcites →https://doi.org/10.1007/978-1-4419-5819-8_6openalex-snapshot
The Tumor Microenvironment
inferredcites →https://doi.org/10.1007/s00280-008-0881-9openalex-snapshot
Cancer and the tumor microenvironment: a review of an essential relationship
inferredcites →https://doi.org/10.1007/s00428-010-0920-xopenalex-snapshot
Would Virchow be a systems biologist? A discourse on the philosophy of science with implications for pathological research
inferredcites →https://doi.org/10.1007/s10585-007-9105-7openalex-snapshot
Contaminating cells alter gene signatures in whole organ versus laser capture microdissected tumors: a comparison of experimental breast cancers and their lymph node metastases
inferredcites →https://doi.org/10.1007/s12022-008-9042-2openalex-snapshot
The Genomic Revolution and Endocrine Pathology
inferredcites →https://doi.org/10.1016/j.devcel.2010.05.012openalex-snapshot
Tumors as Organs: Complex Tissues that Interface with the Entire Organism
inferredcites →https://doi.org/10.1016/j.ejca.2009.02.004openalex-snapshot
A systems pathology model for predicting overall survival in patients with refractory, advanced non-small-cell lung cancer treated with gefitinib
inferredcites →https://doi.org/10.1016/s0002-9440(10)64979-6openalex-snapshot
Molecular Profiling of Clinical Tissue Specimens
inferredcites →https://doi.org/10.1016/s0092-8674(00)81683-9openalex-snapshot
The Hallmarks of Cancer
inferredcites →https://doi.org/10.1016/s1092-9134(98)80052-xopenalex-snapshot
James Ewing: Cancer man
inferredcites →https://doi.org/10.1016/s1525-1578(10)60534-xopenalex-snapshot
Comparison of Snap Freezing versus Ethanol Fixation for Gene Expression Profiling of Tissue Specimens
inferredcites →https://doi.org/10.1016/s1525-1578(10)60617-4openalex-snapshot
Molecular Profiling of Clinical Tissue Specimens
inferredcites →https://doi.org/10.1038/35021093openalex-snapshot
Molecular portraits of human breast tumours
inferredcites →https://doi.org/10.1038/35057062openalex-snapshot
Initial sequencing and analysis of the human genome
inferredcites →https://doi.org/10.1038/461027aopenalex-snapshot
GM crops: Battlefield
inferredcites →https://doi.org/10.1038/463858aopenalex-snapshot
How accurate are cancer cell lines?
inferredcites →https://doi.org/10.1038/labinvest.2010.47openalex-snapshot
Protein pathway biomarker analysis of human cancer reveals requirement for upfront cellular-enrichment processing
inferredcites →https://doi.org/10.1038/labinvest.3700551openalex-snapshot
Why microscopy will remain a cornerstone of surgical pathology
inferredcites →https://doi.org/10.1038/labinvest.3700695openalex-snapshot
‘One medicine—one pathology': are veterinary and human pathology prepared?
inferredcites →https://doi.org/10.1038/nature06358openalex-snapshot
Characterizing the cancer genome in lung adenocarcinoma
inferredcites →https://doi.org/10.1038/nbt0908-978openalex-snapshot
Do-it-yourself (DIY) pathology
inferredcites →https://doi.org/10.1038/nprot.2009.61openalex-snapshot
Quantitative RT-PCR gene expression analysis of laser microdissected tissue samples
inferredcites →https://doi.org/10.1038/nrc2961openalex-snapshot
Why do viruses cause cancer? Highlights of the first century of human tumour virology
inferredcites →https://doi.org/10.1056/nejmoa0905680openalex-snapshot
Tumor-Associated Macrophages and Survival in Classic Hodgkin's Lymphoma
inferredcites →https://doi.org/10.1056/nejmra021902openalex-snapshot
Rules for Making Human Tumor Cells
inferredcites →https://doi.org/10.1080/00365520902898127openalex-snapshot
Gene expression in Barrett's esophagus: Laser capture versus whole tissue
inferredcites →https://doi.org/10.1080/01926230490424662openalex-snapshot
Validation: The New Challenge for Pathology
inferredcites →https://doi.org/10.1093/oxfordjournals.rpd.a006265openalex-snapshot
Target cells in internal dosimetry
inferredcites →https://doi.org/10.1097/00000478-198404000-00008openalex-snapshot
Arthur Purdy Stout (1885–1967)
inferredcites →https://doi.org/10.1097/cco.0b013e3283414d00openalex-snapshot
Next-generation sequencing: emerging lessons on the origins of human cancer
inferredcites →https://doi.org/10.1097/pap.0b013e3181f895c1openalex-snapshot
Human Papillomavirus Detection in Head and Neck Squamous Cell Carcinomas
inferredcites →https://doi.org/10.1097/pdm.0b013e3180de20acopenalex-snapshot
Global Expression Analysis of Prostate Cancer-associated Stroma and Epithelia
inferredcites →https://doi.org/10.1097/ppo.0b013e31819e31cfopenalex-snapshot
Histopathology of Hodgkin’s Lymphoma
inferredcites →https://doi.org/10.1111/j.1365-2303.2010.00818.xopenalex-snapshot
Intraoperative evaluation of sentinel lymph nodes in breast cancer: comparison of frozen sections, imprint cytology and immunocytochemistry
inferredcites →https://doi.org/10.1111/j.1440-1827.1964.tb00676.xopenalex-snapshot
THE FINE STRUCTURE OF LUNG ALVEOLI AND ITS REACTIONS
inferredcites →https://doi.org/10.1111/j.1471-1842.2008.00781.xopenalex-snapshot
Accessing public health information: a preliminary comparison of CABI's global health database and medline
inferredcites →https://doi.org/10.1126/science.1117679openalex-snapshot
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
inferredcites →https://doi.org/10.1126/science.274.5289.998openalex-snapshot
Laser Capture Microdissection
inferredcites →https://doi.org/10.1126/science.276.5311.404openalex-snapshot
Positional Cloning of the Gene for Multiple Endocrine Neoplasia-Type 1
inferredcites →https://doi.org/10.1146/annurev.pathol.3.121806.151442openalex-snapshot
Epigenetic Changes in Cancer
inferredcites →https://doi.org/10.1158/0008-5472.can-08-2984openalex-snapshot
Large-Scale Profiling of Archival Lymph Nodes Reveals Pervasive Remodeling of the Follicular Lymphoma Methylome
inferredcites →https://doi.org/10.1177/104063870701900425openalex-snapshot
From Whence will they Come? — A Perspective on the Acute Shortage of Pathologists in Biomedical Research
inferredcites →https://doi.org/10.1182/blood-2008-07-077982openalex-snapshot
Classification of lymphoid neoplasms: the microscope as a tool for disease discovery
inferredcites →https://doi.org/10.1186/1752-0509-4-162openalex-snapshot
Regulation patterns in signaling networks of cancer
inferredcites →https://doi.org/10.1186/1755-8794-2-13openalex-snapshot
Impact of sample acquisition and linear amplification on gene expression profiling of lung adenocarcinoma: laser capture micro-dissection cell-sampling versus bulk tissue-sampling
inferredcites →https://doi.org/10.1371/journal.pmed.0030208openalex-snapshot
The Limits of Reductionism in Medicine: Could Systems Biology Offer an Alternative?
inferredcites →https://doi.org/10.1371/journal.pone.0014031openalex-snapshot
Computational Micromodel for Epigenetic Mechanisms
inferredcites →https://doi.org/10.1385/mb:29:2:119openalex-snapshot
Optimal Molecular Profiling of Tissue and Tissue Components: Defining the Best Processing and Microdissection Methods for Biomedical Applications
inferredcites →https://doi.org/10.2119/molmed.2008.00120openalex-snapshot
Educational and Social-Ethical Issues in the Pursuit of Molecular Medicine
inferredcites →https://doi.org/10.21775/cimb.005.027openalex-snapshot
Handling of Clinical Tissue Specimens for Molecular Profiling Studies
inferredcites →https://doi.org/10.2353/jmoldx.2009.090040openalex-snapshot
Competency-Based Education for the Molecular Genetic Pathology Fellow
inferredcites →https://doi.org/10.2353/jmoldx.2010.090200openalex-snapshot
Immunoguided Laser Assisted Microdissection Techniques for DNA Methylation Analysis of Archival Tissue Specimens
inferredcites →https://doi.org/10.3324/haematol.2010.033167openalex-snapshot
Methylation profiling of mediastinal gray zone lymphoma reveals a distinctive signature with elements shared by classical Hodgkin's lymphoma and primary mediastinal large B-cell lymphoma
inferredcites →https://doi.org/10.4161/cc.5.15.3112openalex-snapshot
Stromal Fibroblasts in Cancer: A Novel Tumor-Promoting Cell Type
inferredcites →https://doi.org/10.4161/cc.7.5.5547openalex-snapshot
MicroRNAs in malignant progression
inferredcites →https://doi.org/10.5858/2008-132-774-icsptfopenalex-snapshot
Is Clinical Systems Pathology the Future of Pathology?
inferredcites →https://doi.org/10.5858/2010-0413-rar.1openalex-snapshot
Molecular Testing of Solid Tumors
inferredcites →https://doi.org/10.7208/chicago/9780226458106.001.0001openalex-snapshot
The Structure of Scientific Revolutions

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4675577openalex-extracted
Assessment and Comparing the Effectiveness of Tumor-Induced Mscs on Cell Growth and Development in Different Cancer Types in Vitro and in Vivo
inferred← citeshttps://doi.org/10.1007/s00292-018-0458-2openalex-snapshot
Histopathologische Forschungslabors in der translationalen Forschung
inferred← citeshttps://doi.org/10.1007/s00428-020-02757-0openalex-snapshot
The leading role of pathology in assessing the somatic molecular alterations of cancer: Position Paper of the European Society of Pathology
inferred← citeshttps://doi.org/10.1007/s10911-015-9341-4openalex-snapshot
Of Mice and Women: A Comparative Tissue Biology Perspective of Breast Stem Cells and Differentiation
inferred← citeshttps://doi.org/10.1007/s11060-026-05470-1openalex-snapshot
Impact of an evolving classification system on diffuse glioma repositories: experience from the Sydney brain tumour bank
inferred← citeshttps://doi.org/10.1016/j.annpat.2012.12.003openalex-snapshot
Mise en place d’un secteur de pathologie moléculaire en oncologie au sein d’un laboratoire d’anatomie pathologique (LPCE, CHU de Nice)
inferred← citeshttps://doi.org/10.1016/j.arcmed.2025.103212openalex-snapshot
Effectiveness of Tumor-induced Mesenchymal Stem Cells on Cell Growth and Development in Different Cancer Types In Vitro and In Vivo Models
inferred← citeshttps://doi.org/10.1038/s41587-025-02585-0openalex-snapshot
High-dimensional imaging using combinatorial channel multiplexing and deep learning
inferred← citeshttps://doi.org/10.1038/s41698-022-00252-0openalex-snapshot
A deep learning model for molecular label transfer that enables cancer cell identification from histopathology images
inferred← citeshttps://doi.org/10.1089/nat.2015.0569openalex-snapshot
The Application of Aptamers for Immunohistochemistry
inferred← citeshttps://doi.org/10.1101/2023.09.09.556962openalex-snapshot
Escalating High-dimensional Imaging using Combinatorial Channel Multiplexing and Deep Learning
inferred← citeshttps://doi.org/10.1136/bmjonc-2026-001102openalex-snapshot
Foundation models in computational pathology: methods, applications and clinical implications
inferred← citeshttps://doi.org/10.1136/jclinpath-2014-202176openalex-snapshot
Integrating molecular diagnostics into histopathology training: the Belfast model
inferred← citeshttps://doi.org/10.1142/s0218001425570150openalex-snapshot
BC-MBINet: A Novel Architecture for Accurate Classification of Breast Cancer with Microscopic Biopsy Images Using Deep Convolutional Neural Networks
inferred← citeshttps://doi.org/10.1177/0300985813510533openalex-snapshot
Laser Capture Microdissection for the Investigative Pathologist
inferred← citeshttps://doi.org/10.1371/journal.pone.0057613openalex-snapshot
The Use of Sensitive Chemical Antibodies for Diagnosis: Detection of Low Levels of Epcam in Breast Cancer
inferred← citeshttps://doi.org/10.2478/macvetrev-2026-0015openalex-snapshot
Diagnostic Techniques Used in Veterinary Oncology: Useful but with Problems. What Can A Veterinary Oncologist Do?
inferred← citeshttps://doi.org/10.26599/bdma.2024.9020057openalex-snapshot
SeaConvNeXt: A Lightweight Two-Branch Network Architecture for Efficient Prediction of Specific IHC Proteins and Antigens on Hematoxylin and Eosin (H&E) Images
inferred← citeshttps://doi.org/10.3748/wjg.v18.i45.6532openalex-snapshot
Tumor budding as a potential histopathological biomarker in colorectal cancer: Hype or hope?
inferred← citeshttps://doi.org/10.7759/cureus.10513openalex-snapshot
Contribution of Pathologists in Leading Clinical Cancer Research Through Interdisciplinary Collaboration in Saudi Arabia
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