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Microfluidic blood–brain barrier model provides in vivo‐like barrier properties for drug permeability screening
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/9781118286067openalex-snapshot
Absorption and Drug Development
inferredcites →https://doi.org/10.1002/jps.24329openalex-snapshot
In Vitro Blood–Brain Barrier Models—An Overview of Established Models and New Microfluidic Approaches
inferredcites →https://doi.org/10.1007/978-1-61779-185-7_25openalex-snapshot
Claudin-5 Expression in In Vitro Models of the Blood–Brain Barrier
inferredcites →https://doi.org/10.1007/s10439-014-1086-5openalex-snapshot
Permeability Analysis of Neuroactive Drugs Through a Dynamic Microfluidic In Vitro Blood–Brain Barrier Model
inferredcites →https://doi.org/10.1007/s10544-012-9680-5openalex-snapshot
Reliable permeability assay system in a microfluidic device mimicking cerebral vasculatures
inferredcites →https://doi.org/10.1007/s10544-012-9699-7openalex-snapshot
BBB ON CHIP: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function
inferredcites →https://doi.org/10.1007/s10928-011-9229-xopenalex-snapshot
BioDMET: a physiologically based pharmacokinetic simulation tool for assessing proposed solutions to complex biological problems
inferredcites →https://doi.org/10.1007/s11095-007-9254-zopenalex-snapshot
Polyspecific Organic Cation Transporters: Structure, Function, Physiological Roles, and Biopharmaceutical Implications
inferredcites →https://doi.org/10.1007/s11095-007-9379-0openalex-snapshot
Blood–Brain Barrier Transport of Therapeutics via Receptor-Mediation
inferredcites →https://doi.org/10.1016/0006-2952(95)00082-bopenalex-snapshot
In vivo and in vitro evidence for ATP-dependency of P-glycoprotein-mediated efflux of doxorubicin at the blood-brain barrier
inferredcites →https://doi.org/10.1016/0024-3205(82)90715-9openalex-snapshot
Blood-brain barrier transport of caffeine: Dose-related restriction of adenine transport
inferredcites →https://doi.org/10.1016/j.biomaterials.2008.01.030openalex-snapshot
Extended delivery of ophthalmic drugs by silicone hydrogel contact lenses
inferredcites →https://doi.org/10.1016/j.brainres.2006.06.027openalex-snapshot
Side by side comparison between dynamic versus static models of blood–brain barrier in vitro: A permeability study
inferredcites →https://doi.org/10.1016/j.brainres.2012.08.031openalex-snapshot
An immortalised astrocyte cell line maintains the in vivo phenotype of a primary porcine in vitro blood–brain barrier model
inferredcites →https://doi.org/10.1016/j.cardiores.2007.04.017openalex-snapshot
Regulation of endothelial barrier function during flow-induced conversion to an arterial phenotype
inferredcites →https://doi.org/10.1016/j.mvr.2008.08.004openalex-snapshot
Non-invasive measurement of solute permeability in cerebral microvessels of the rat
inferredcites →https://doi.org/10.1016/j.mvr.2015.02.008openalex-snapshot
Human brain microvascular endothelial cells resist elongation due to shear stress
inferredcites →https://doi.org/10.1016/j.snb.2015.07.110openalex-snapshot
A versatile lab-on-a-chip tool for modeling biological barriers
inferredcites →https://doi.org/10.1016/s1046-2023(03)00029-xopenalex-snapshot
Functional analysis of tight junctions
inferredcites →https://doi.org/10.1038/331168a0openalex-snapshot
Haemodynamic shear stress activates a K+ current in vascular endothelial cells
inferredcites →https://doi.org/10.1038/jcbfm.2010.162openalex-snapshot
A Dynamic in vitro BBB Model for the Study of Immune Cell Trafficking into the Central Nervous System
inferredcites →https://doi.org/10.1038/jcbfm.2013.169openalex-snapshot
Stroke-Induced Brain Parenchymal Injury Drives Blood–Brain Barrier Early Leakage Kinetics: A Combined in Vivo / in Vitro Study
inferredcites →https://doi.org/10.1038/nbt.2247openalex-snapshot
Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells
inferredcites →https://doi.org/10.1038/ncomms4413openalex-snapshot
Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity
inferredcites →https://doi.org/10.1038/ncomms5250openalex-snapshot
Reconfigurable microfluidic hanging drop network for multi-tissue interaction and analysis
inferredcites →https://doi.org/10.1038/sj.bjp.0703959openalex-snapshot
Chronic vascular toxicity of doxorubicin in an organ‐cultured artery
inferredcites →https://doi.org/10.1038/srep04160openalex-snapshot
A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources
inferredcites →https://doi.org/10.1038/srep04681openalex-snapshot
Brain microvascular endothelial cells resist elongation due to curvature and shear stress
inferredcites →https://doi.org/10.1038/srep11990openalex-snapshot
LRP-1-mediated intracellular antibody delivery to the Central Nervous System
inferredcites →https://doi.org/10.1038/srep15222openalex-snapshot
Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular Pathology
inferredcites →https://doi.org/10.1039/b909900jopenalex-snapshot
Fundamentals of microfluidic cell culture in controlled microenvironments
inferredcites →https://doi.org/10.1039/b917763aopenalex-snapshot
A microfluidic device for a pharmacokinetic–pharmacodynamic (PK–PD) model on a chip
inferredcites →https://doi.org/10.1039/c0lc00272kopenalex-snapshot
Simple room temperature bonding of thermoplastics and poly(dimethylsiloxane)
inferredcites →https://doi.org/10.1039/c2lc40094dopenalex-snapshot
Characterization of a microfluidic in vitro model of the blood-brain barrier (μBBB)
inferredcites →https://doi.org/10.1039/c2lc41033hopenalex-snapshot
A modular approach to create a neurovascular unit-on-a-chip
inferredcites →https://doi.org/10.1039/c2lc41208jopenalex-snapshot
SyM-BBB: a microfluidic blood brain barrier model
inferredcites →https://doi.org/10.1039/c3lc41017jopenalex-snapshot
Microfabricated mammalian organ systems and their integration into models of whole animals and humans
inferredcites →https://doi.org/10.1039/c4ib00292jopenalex-snapshot
Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling
inferredcites →https://doi.org/10.1039/c4lc00999aopenalex-snapshot
Pumpless microfluidic platform for drug testing on human skin equivalents
inferredcites →https://doi.org/10.1039/c5lc00237kopenalex-snapshot
Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow
inferredcites →https://doi.org/10.1039/c5lc00392jopenalex-snapshot
A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
inferredcites →https://doi.org/10.1046/j.1469-7580.2002.00064.xopenalex-snapshot
Astrocyte–endothelial interactions and blood–brain barrier permeability*
inferredcites →https://doi.org/10.1063/1.4917508openalex-snapshot
Collagen-based brain microvasculature modelin vitrousing three-dimensional printed template
inferredcites →https://doi.org/10.1063/1.4934713openalex-snapshot
Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor
inferredcites →https://doi.org/10.1073/pnas.95.26.15741openalex-snapshot
Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex
inferredcites →https://doi.org/10.1074/jbc.272.2.1395openalex-snapshot
Differential Effect of Shear Stress on Extracellular Signal-regulated Kinase and N-terminal Jun Kinase in Endothelial Cells
inferredcites →https://doi.org/10.1074/jbc.273.45.29745openalex-snapshot
The Tight Junction Protein ZO-1 Establishes a Link between the Transmembrane Protein Occludin and the Actin Cytoskeleton
inferredcites →https://doi.org/10.1074/jbc.m003890200openalex-snapshot
Doxorubicin-induced Apoptosis in Endothelial Cells and Cardiomyocytes Is Ameliorated by Nitrone Spin Traps and Ebselen
inferredcites →https://doi.org/10.1074/jbc.m110.189381openalex-snapshot
Transport of Arylsulfatase A across the Blood-Brain Barrier in Vitro
inferredcites →https://doi.org/10.1091/mbc.e09-04-0320openalex-snapshot
ZO-1 Stabilizes the Tight Junction Solute Barrier through Coupling to the Perijunctional Cytoskeleton
inferredcites →https://doi.org/10.1091/mbc.e09-10-0876openalex-snapshot
Abl Tyrosine Kinase Phosphorylates Nonmuscle Myosin Light Chain Kinase to Regulate Endothelial Barrier Function
inferredcites →https://doi.org/10.1096/fasebj.26.1_supplement.894.10openalex-snapshot
Gap junction blockade in the locus coeruleus (LC) decreases the hypercapnic ventilatory response
inferredcites →https://doi.org/10.1096/fj.04-3458fjeopenalex-snapshot
Blood‐brain barrier‐specific properties of a human adult brain endothelial cell line
inferredcites →https://doi.org/10.1115/1.4025892openalex-snapshot
Quantification of Blood-Brain Barrier Solute Permeability and Brain Transport by Multiphoton Microscopy
inferredcites →https://doi.org/10.1126/science.1151526openalex-snapshot
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
inferredcites →https://doi.org/10.1126/scitranslmed.3002230openalex-snapshot
Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target
inferredcites →https://doi.org/10.1146/annurev-bioeng-071910-124629openalex-snapshot
The Role of Body-on-a-Chip Devices in Drug and Toxicity Studies
inferredcites →https://doi.org/10.1152/ajpheart.01047.2006openalex-snapshot
Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell
inferredcites →https://doi.org/10.1161/01.res.0000259561.23876.c5openalex-snapshot
Regulation of Endothelial Cell Cycle by Laminar Versus Oscillatory Flow
inferredcites →https://doi.org/10.1161/01.res.82.10.1094openalex-snapshot
Oscillatory and Steady Laminar Shear Stress Differentially Affect Human Endothelial Redox State
inferredcites →https://doi.org/10.1161/01.res.82.5.532openalex-snapshot
Oscillatory Shear Stress Stimulates Adhesion Molecule Expression in Cultured Human Endothelium
inferredcites →https://doi.org/10.1161/atvbaha.113.301826openalex-snapshot
Endothelial Cell Sensing of Flow Direction
inferredcites →https://doi.org/10.1161/strokeaha.108.528091openalex-snapshot
Effect of Aging on Elastin Functionality in Human Cerebral Arteries
inferredcites →https://doi.org/10.1177/2211068214561025openalex-snapshot
TEER Measurement Techniques for In Vitro Barrier Model Systems
inferredcites →https://doi.org/10.1186/1471-2407-6-186openalex-snapshot
The claudin gene family: expression in normal and neoplastic tissues
inferredcites →https://doi.org/10.1186/scrt361openalex-snapshot
The National Institutes of Health Microphysiological Systems Program focuses on a critical challenge in the drug discovery pipeline
inferredcites →https://doi.org/10.1602/neurorx.2.1.3openalex-snapshot
The blood-brain barrier: Bottleneck in brain drug development
inferredcites →https://doi.org/10.2174/138920013804545232openalex-snapshot
Hurdles with Using In Vitro Models to Predict Human Blood-brain Barrier Drug Permeability: A Special Focus on Transporters and Metabolizing Enzymes
inferredcites →https://doi.org/10.2174/1389200211309010120openalex-snapshot
Hurdles with Using In Vitro Models to Predict Human Blood-brain Barrier Drug Permeability: A Special Focus on Transporters and Metabolizing Enzymes
inferredcites →https://doi.org/10.3389/fneng.2013.00007openalex-snapshot
The blood-brain barrier: an engineering perspective
inferredcites →https://doi.org/10.4172/2157-7439.1000225openalex-snapshot
The Influence of Silver Nanoparticles on the Blood-Brain and the Blood-Cerebrospinal Fluid Barrier in vitro
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In Vitro Models of the Blood–Brain Barrier
inferred← citeshttps://doi.org/10.1007/978-1-0716-4474-4_8openalex-snapshot
Transepithelial/Transendothelial Electrical Resistance (TEER) to Measure the Integrity of Blood-Brain Barrier
inferred← citeshttps://doi.org/10.1007/978-1-0716-4530-7_12openalex-snapshot
Utility of Induced Pluripotent Stem Cell-Based Microphysiological Systems for Drug Development and Testing
inferred← citeshttps://doi.org/10.1007/978-1-4939-8946-1_4openalex-snapshot
In Vitro BBB Models: Working with Static Platforms and Microfluidic Systems
inferred← citeshttps://doi.org/10.1007/978-1-4939-8946-1_6openalex-snapshot
Transepithelial/Transendothelial Electrical Resistance (TEER) to Measure the Integrity of Blood-Brain Barrier
inferred← citeshttps://doi.org/10.1007/978-3-030-19515-1_8openalex-snapshot
Structural and Functional Characteristics of the Human Blood-Nerve Barrier with Translational Implications to Peripheral Nerve Autoimmune Disorders
inferred← citeshttps://doi.org/10.1007/978-3-030-36588-2_6openalex-snapshot
Microfluidic Systems in CNS Studies
inferred← citeshttps://doi.org/10.1007/978-3-030-85397-6_11openalex-snapshot
Emerging Biomedical and Industrial Applications of Nanoporous Materials
inferred← citeshttps://doi.org/10.1007/978-3-030-88773-5_9openalex-snapshot
Human In Vitro Blood-Brain Barrier Models Derived from Stem Cells
inferred← citeshttps://doi.org/10.1007/978-3-031-11409-0_1openalex-snapshot
Configurable Models of the Neurovascular Unit
inferred← citeshttps://doi.org/10.1007/978-3-031-24297-7_8-1openalex-snapshot
Structural and Functional Characteristics of the Human Blood-Nerve Barrier with Translational Implications to Peripheral Nerve Autoimmune Disorders
inferred← citeshttps://doi.org/10.1007/978-3-031-60006-7_8openalex-snapshot
Structural and Functional Characteristics of the Human Blood-Nerve Barrier with Translational Implications to Peripheral Nerve Autoimmune Disorders
inferred← citeshttps://doi.org/10.1007/978-3-031-61992-2_5openalex-snapshot
The Guardian of the Brain: Understanding the Blood–Brain Barrier and its Role in CNS Drug Discovery
inferred← citeshttps://doi.org/10.1007/978-3-031-87744-5_10openalex-snapshot
Smart Bio-Inspired Structures: Organ-on-Chip
inferred← citeshttps://doi.org/10.1007/978-3-319-92946-0_17openalex-snapshot
New Frontiers in Cardiovascular Research: Microfluidic Modeling of Cardiovascular Diseases and Applications for Hypertension Research
inferred← citeshttps://doi.org/10.1007/978-981-13-6229-3_9openalex-snapshot
In Vitro Tissue Construction for Organ-on-a-Chip Applications
inferred← citeshttps://doi.org/10.1007/978-981-16-9232-1_6openalex-snapshot
Organ-on-a-Chip: Novel In Vitro Model for Drug Discovery
inferred← citeshttps://doi.org/10.1007/978-981-19-1379-2_24openalex-snapshot
Application of Organ-on-Chip in Blood Brain Barrier Model
inferred← citeshttps://doi.org/10.1007/978-981-97-6540-9_9openalex-snapshot
In Vitro Tissue Construction for Organ-on-a-Chip Applications
inferred← citeshttps://doi.org/10.1007/978-981-97-9495-9_14openalex-snapshot
Construction and Functional Evaluation of 2D and 3D Human Blood–Brain Barrier Models
inferred← citeshttps://doi.org/10.1007/s00204-025-04169-yopenalex-snapshot
Revolutionizing toxicological risk assessment: integrative advances in new approach methodologies (NAMs) and precision toxicology
inferred← citeshttps://doi.org/10.1007/s00216-022-03991-yopenalex-snapshot
Evaluation and optimization of PolyJet 3D-printed materials for cell culture studies
inferred← citeshttps://doi.org/10.1007/s00216-025-05958-1openalex-snapshot
Evaluation of fused deposition modeling (FDM)-printed devices for microfluidic-based cell culture studies
inferred← citeshttps://doi.org/10.1007/s00221-025-07134-4openalex-snapshot
Pericyte loss: a key factor inducing brain Aβ40 accumulation and neuronal degeneration in cerebral amyloid angiopathy
inferred← citeshttps://doi.org/10.1007/s10404-021-02428-9openalex-snapshot
Isolation of primary brain endothelial cells, pericytes and astrocytes on a microfluidic immunopanning chip (MIC)
inferred← citeshttps://doi.org/10.1007/s10404-024-02741-zopenalex-snapshot
Advances in modeling permeability and selectivity of the blood-brain barrier using microfluidics
inferred← citeshttps://doi.org/10.1007/s10439-018-02124-wopenalex-snapshot
In Vitro Models for Studying Transport Across Epithelial Tissue Barriers
inferred← citeshttps://doi.org/10.1007/s10439-019-02405-yopenalex-snapshot
A Reconfigurable In Vitro Model for Studying the Blood–Brain Barrier
inferred← citeshttps://doi.org/10.1007/s10439-020-02498-wopenalex-snapshot
Biomaterials and Culture Systems for Development of Organoid and Organ-on-a-Chip Models
inferred← citeshttps://doi.org/10.1007/s10456-025-10010-yopenalex-snapshot
Multidirectional interstitial flow promotes microvascular network formation: insights from a square chip-based platform
inferred← citeshttps://doi.org/10.1007/s10544-017-0251-7openalex-snapshot
Finite element modeling to analyze TEER values across silicon nanomembranes
inferred← citeshttps://doi.org/10.1007/s10544-020-00515-2openalex-snapshot
Pumpless microfluidic device with open top cell culture under oscillatory shear stress
inferred← citeshttps://doi.org/10.1007/s11064-025-04333-xopenalex-snapshot
Nanoparticle Interactions with the Blood Brain Barrier: Insights from Drosophila and Implications for Human Astrocyte Targeted Therapies
inferred← citeshttps://doi.org/10.1007/s11426-025-2982-3openalex-snapshot
PROTAC-based degradation of catechol-O-methyltransferase for potential treatment of Parkinson’s disease
inferred← citeshttps://doi.org/10.1007/s11626-020-00486-xopenalex-snapshot
Three-dimensional co-culture of blood-brain barrier-composing cells in a culture insert with a collagen vitrigel membrane
inferred← citeshttps://doi.org/10.1007/s12015-020-10068-9openalex-snapshot
Modeling neurodegenerative diseases with cerebral organoids and other three-dimensional culture systems: focus on Alzheimer’s disease
inferred← citeshttps://doi.org/10.1007/s12035-019-01653-2openalex-snapshot
Microfluidic Brain-on-a-Chip: Perspectives for Mimicking Neural System Disorders
inferred← citeshttps://doi.org/10.1007/s12035-024-04506-9openalex-snapshot
The Multifaceted Role of L-Type Amino Acid Transporter 1 at the Blood–Brain Barrier: Structural Implications and Therapeutic Potential
inferred← citeshttps://doi.org/10.1007/s12035-026-05898-6openalex-snapshot
Engineered Exosomes: Innovative Strategies for Precision Drug Delivery in Parkinson’s Disease
inferred← citeshttps://doi.org/10.1007/s12274-023-5651-9openalex-snapshot
Sensors-integrated organ-on-a-chip for biomedical applications
inferred← citeshttps://doi.org/10.1007/s12640-021-00431-0openalex-snapshot
The Blood–Brain Barrier: Much More Than a Selective Access to the Brain
inferred← citeshttps://doi.org/10.1007/s13139-018-00567-6openalex-snapshot
Perspective in Nuclear Theranostics Using Exosome for the Brain
inferred← citeshttps://doi.org/10.1007/s13206-019-3201-zopenalex-snapshot
Mimicking the Human Physiology with Microphysiological Systems (MPS)
inferred← citeshttps://doi.org/10.1007/s13206-025-00243-wopenalex-snapshot
Organ-on-a-Chip Models for Studying Gut–Brain Axis and Appetite Regulation
inferred← citeshttps://doi.org/10.1007/s13346-018-0548-yopenalex-snapshot
Stem cells technology: a powerful tool behind new brain treatments
inferred← citeshttps://doi.org/10.1007/s40778-017-0080-xopenalex-snapshot
Organoid and Organ-on-a-Chip Systems: New Paradigms for Modeling Neurological and Gastrointestinal Disease
inferred← citeshttps://doi.org/10.1007/s42765-021-00091-xopenalex-snapshot
Multi-compartment Organ-on-a-Chip Based on Electrospun Nanofiber Membrane as In Vitro Jaundice Disease Model
inferred← citeshttps://doi.org/10.1016/b978-0-12-813671-3.00009-8openalex-snapshot
Neural tissue microphysiological systems in the era of patient-derived pluripotent stem cells
inferred← citeshttps://doi.org/10.1016/b978-0-12-816221-7.00005-7openalex-snapshot
Advanced microtechnologies for high-throughput screening
inferred← citeshttps://doi.org/10.1016/b978-0-12-817202-5.00003-6openalex-snapshot
Organs-on-a-chip engineering
inferred← citeshttps://doi.org/10.1016/b978-0-12-818791-3.00002-4openalex-snapshot
Microchannels for microfluidic systems
inferred← citeshttps://doi.org/10.1016/b978-0-12-819666-3.00009-2openalex-snapshot
Metallic-based nanocarriers: methods employed in nanoparticle characterization and assessing the interaction with the blood–brain barrier
inferred← citeshttps://doi.org/10.1016/b978-0-12-822231-7.00003-5openalex-snapshot
In vitro blood–brain barrier model derived from human iPS cells and its applications
inferred← citeshttps://doi.org/10.1016/b978-0-12-822425-0.00010-5openalex-snapshot
Microfluidic assembly for biosensing
inferred← citeshttps://doi.org/10.1016/b978-0-323-85764-2.00009-0openalex-snapshot
Studying non–cell-autonomous neurodegeneration in Parkinson’s disease with induced pluripotent stem cells
inferred← citeshttps://doi.org/10.1016/b978-0-443-13782-2.00012-7openalex-snapshot
Primary cell culture for organ-on-a-chip
inferred← citeshttps://doi.org/10.1016/b978-0-443-13782-2.00014-0openalex-snapshot
Organ-on-a-chip for blood–brain barrier studies
inferred← citeshttps://doi.org/10.1016/b978-0-443-15510-9.00005-0openalex-snapshot
Multicompartmental dynamic models for permeability studies
inferred← citeshttps://doi.org/10.1016/b978-0-443-15510-9.00022-0openalex-snapshot
Tissue-based in vitro and ex vivo models for blood–brain barrier permeability studies
inferred← citeshttps://doi.org/10.1016/b978-0-443-15510-9.00023-2openalex-snapshot
Organ-on-chip models for blood–brain barrier permeability studies
inferred← citeshttps://doi.org/10.1016/j.actbio.2019.04.032openalex-snapshot
Integration of biological systems with electronic-mechanical assemblies
inferred← citeshttps://doi.org/10.1016/j.actbio.2019.04.053openalex-snapshot
AKR1B10 (Aldo-keto reductase family 1 B10) promotes brain metastasis of lung cancer cells in a multi-organ microfluidic chip model
inferred← citeshttps://doi.org/10.1016/j.actbio.2025.03.041openalex-snapshot
Recent advances in blood-brain barrier-on-a-chip models
inferred← citeshttps://doi.org/10.1016/j.addr.2018.09.009openalex-snapshot
Utilizing microphysiological systems and induced pluripotent stem cells for disease modeling: a case study for blood brain barrier research in a pharmaceutical setting
inferred← citeshttps://doi.org/10.1016/j.addr.2022.114183openalex-snapshot
Breaking through the barrier: Modelling and exploiting the physical microenvironment to enhance drug transport and efficacy
inferred← citeshttps://doi.org/10.1016/j.addr.2023.114777openalex-snapshot
From cells to organoids: The evolution of blood-brain barrier technology for modelling drug delivery in brain cancer
inferred← citeshttps://doi.org/10.1016/j.addr.2025.115736openalex-snapshot
Informing development of brain cancer therapies within "preclinical trials" using ex vivo patient tumors
inferred← citeshttps://doi.org/10.1016/j.addr.2026.115865openalex-snapshot
Microfluidic platforms for precision delivery of therapeutic cells in regenerative and personalized medicine
inferred← citeshttps://doi.org/10.1016/j.arr.2024.102291openalex-snapshot
Treating Alzheimer’s disease using nanoparticle-mediated drug delivery strategies/systems
inferred← citeshttps://doi.org/10.1016/j.arr.2024.102394openalex-snapshot
Delineation of the role of G6PD in Alzheimer’s disease and potential enhancement through microfluidic and nanoparticle approaches
inferred← citeshttps://doi.org/10.1016/j.bbadis.2018.12.009openalex-snapshot
Neurological diseases at the blood-brain barrier: Stemming new scientific paradigms using patient-derived induced pluripotent cells
inferred← citeshttps://doi.org/10.1016/j.bbrep.2021.101096openalex-snapshot
The effect of serum starvation on tight junctional proteins and barrier formation in Caco-2 cells
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2025.10.018openalex-snapshot
Human in vitro models of neurovasculature and the application to pre-clinical intracerebral haemorrhage research
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2018.05.012openalex-snapshot
Advances in ex vivo models and lab-on-a-chip devices for neural tissue engineering
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2018.07.014openalex-snapshot
3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2018.07.062openalex-snapshot
Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2018.10.023openalex-snapshot
Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2019.05.022openalex-snapshot
An on-chip model of protein paracellular and transcellular permeability in the microcirculation
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2019.119732openalex-snapshot
Microphysiological systems for recapitulating physiology and function of blood-brain barrier
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2022.121531openalex-snapshot
Brain-on-a-chip: Recent advances in design and techniques for microfluidic models of the brain in health and disease
inferred← citeshttps://doi.org/10.1016/j.bios.2021.113150openalex-snapshot
Plasmonic sensing, imaging, and stimulation techniques for neuron studies
inferred← citeshttps://doi.org/10.1016/j.bios.2022.115057openalex-snapshot
Integrated technologies for continuous monitoring of organs-on-chips: Current challenges and potential solutions
inferred← citeshttps://doi.org/10.1016/j.bios.2023.115100openalex-snapshot
Biosensor integrated brain-on-a-chip platforms: Progress and prospects in clinical translation
inferred← citeshttps://doi.org/10.1016/j.bios.2023.115271openalex-snapshot
Organs-on-chips technologies – A guide from disease models to opportunities for drug development
inferred← citeshttps://doi.org/10.1016/j.biosx.2024.100480openalex-snapshot
Advancement of organ-on-chip towards next generation medical technology
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2025.108637openalex-snapshot
A novel member of biomimetic nano vesicles: Functional properties and research progress of hybrid-membered nanovesicles
inferred← citeshttps://doi.org/10.1016/j.bprint.2019.e00069openalex-snapshot
Multilayered microcasting of agarose–collagen composites for neurovascular modeling
inferred← citeshttps://doi.org/10.1016/j.bprint.2026.e00499openalex-snapshot
Reconstructing the glioblastoma tumor microenvironment using 3D bioprinting: Opportunities, challenges, and future directions
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2019.04.027openalex-snapshot
Assessing drug response in engineered brain microenvironments
inferred← citeshttps://doi.org/10.1016/j.cbi.2026.112206openalex-snapshot
A microfluidic human blood–brain barrier model reveals neurovascular toxicity and barrier disruption induced by E-cigarette additives
inferred← citeshttps://doi.org/10.1016/j.cca.2025.120796openalex-snapshot
Microfluidic biosensors and devices for brain tumor diagnosis and monitoring
inferred← citeshttps://doi.org/10.1016/j.cobme.2017.11.002openalex-snapshot
Modeling the blood–brain barrier: Beyond the endothelial cells
inferred← citeshttps://doi.org/10.1016/j.cobme.2019.12.011openalex-snapshot
Microphysiological models of neurological disorders for drug development
inferred← citeshttps://doi.org/10.1016/j.cobme.2020.05.003openalex-snapshot
Recent advancements in microphysiological systems for neural development and disease
inferred← citeshttps://doi.org/10.1016/j.cobme.2025.100588openalex-snapshot
Trans-epithelial/endothelial electrical resistance (TEER): Current state of integrated TEER measurements in organ-on-a-chip devices
inferred← citeshttps://doi.org/10.1016/j.coche.2020.05.006openalex-snapshot
Advances and opportunities for hiPSC-derived models of the blood-brain barrier
inferred← citeshttps://doi.org/10.1016/j.coche.2020.07.002openalex-snapshot
In vitro models of the blood-brain barrier: building in physiological complexity
inferred← citeshttps://doi.org/10.1016/j.colsurfa.2026.140139openalex-snapshot
Investigation of permeability and flow dynamics in liver on a chip: An integrated experimental and computational study
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2022.112775openalex-snapshot
Ultrathin and handleable nanofibrous net as a novel biomimetic basement membrane material for endothelial barrier formation
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2023.113431openalex-snapshot
Recent advances in sensor-integrated brain-on-a-chip devices for real-time brain monitoring
inferred← citeshttps://doi.org/10.1016/j.copbio.2020.06.009openalex-snapshot
Advances in microphysiological blood-brain barrier (BBB) models towards drug delivery
inferred← citeshttps://doi.org/10.1016/j.dmpk.2025.101058openalex-snapshot
Functional assessment of immortalized human brain microvascular endothelial cells with different passage numbers: A case study for a prospective proposal on variability management of in vitro blood-brain barrier models
inferred← citeshttps://doi.org/10.1016/j.drudis.2018.01.036openalex-snapshot
Microfluidic platforms for modeling biological barriers in the circulatory system
inferred← citeshttps://doi.org/10.1016/j.drudis.2019.08.001openalex-snapshot
A human-on-a-chip approach to tackling rare diseases
inferred← citeshttps://doi.org/10.1016/j.drudis.2020.11.009openalex-snapshot
Advances in 3D neural, vascular and neurovascular models for drug testing and regenerative medicine
inferred← citeshttps://doi.org/10.1016/j.drup.2021.100753openalex-snapshot
In vitro biomimetic models for glioblastoma-a promising tool for drug response studies
inferred← citeshttps://doi.org/10.1016/j.ejphar.2025.177872openalex-snapshot
Blood-brain barriers and drug pharmacokinetics: mechanisms and models
inferred← citeshttps://doi.org/10.1016/j.envpol.2020.115861openalex-snapshot
Environmental toxicology wars: Organ-on-a-chip for assessing the toxicity of environmental pollutants
inferred← citeshttps://doi.org/10.1016/j.eurpolymj.2025.114459openalex-snapshot
Advancing colon targeting: Natural polymer systems for drug delivery
inferred← citeshttps://doi.org/10.1016/j.expneurol.2020.113272openalex-snapshot
Biology of the human blood-nerve barrier in health and disease
inferred← citeshttps://doi.org/10.1016/j.ijft.2024.100948openalex-snapshot
Using molecular dynamics simulation to examine the evolution of blood barrier structure in the presence of different electric fields
inferred← citeshttps://doi.org/10.1016/j.isci.2019.10.052openalex-snapshot
Instrumented Microphysiological Systems for Real-Time Measurement and Manipulation of Cellular Electrochemical Processes
inferred← citeshttps://doi.org/10.1016/j.isci.2020.101719openalex-snapshot
A Tissue Engineering Approach to Metastatic Colon Cancer
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2022.09.005openalex-snapshot
Perfusion culture of endothelial cells under shear stress on microporous membrane in a pressure-driven microphysiological system
inferred← citeshttps://doi.org/10.1016/j.jconrel.2018.09.015openalex-snapshot
A filter-free blood-brain barrier model to quantitatively study transendothelial delivery of nanoparticles by fluorescence spectroscopy
inferred← citeshttps://doi.org/10.1016/j.jconrel.2022.01.011openalex-snapshot
In vitro blood brain barrier models: An overview
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