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In vitro and in vivo evaluation of 3D constructs engineered with human iPSC‐derived chondrocytes in gelatin methacryloyl hydrogel

https://doi.org/10.1002/bit.28168
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/1529-0131(200101)44:1<85::aid-anr12>3.0.co;2-6openalex-snapshot
Human periosteum-derived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor age
inferredcites →https://doi.org/10.1002/adhm.201700298openalex-snapshot
3D Bioprinting for Cartilage and Osteochondral Tissue Engineering
inferredcites →https://doi.org/10.1002/adhm.202100878openalex-snapshot
Systematic Comparison of Biomaterials‐Based Strategies for Osteochondral and Chondral Repair in Large Animal Models
inferredcites →https://doi.org/10.1002/mabi.201200471openalex-snapshot
Gelatin‐Methacrylamide Hydrogels as Potential Biomaterials for Fabrication of Tissue‐Engineered Cartilage Constructs
inferredcites →https://doi.org/10.1002/mabi.202000401openalex-snapshot
Tuning the Phenotype of Cartilage Tissue Mimics by Varying Spheroid Maturation and Methacrylamide‐Modified Gelatin Hydrogel Characteristics
inferredcites →https://doi.org/10.1002/term.3273openalex-snapshot
Gelatin methacryloyl as environment for chondrocytes and cell delivery to superficial cartilage defects
inferredcites →https://doi.org/10.1002/term.501openalex-snapshot
The influence of matrix elasticity on chondrocyte behavior in 3D
inferredcites →https://doi.org/10.1006/meth.2001.1262openalex-snapshot
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
inferredcites →https://doi.org/10.1007/s00167-016-4300-1openalex-snapshot
Comparative efficacy of cartilage repair procedures in the knee: a network meta-analysis
inferredcites →https://doi.org/10.1007/s00264-014-2402-2openalex-snapshot
Skeletal tissue regeneration: where can hydrogels play a role?
inferredcites →https://doi.org/10.1007/s00441-021-03498-5openalex-snapshot
Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells
inferredcites →https://doi.org/10.1016/j.actbio.2017.01.036openalex-snapshot
Cell-laden hydrogels for osteochondral and cartilage tissue engineering
inferredcites →https://doi.org/10.1016/j.actbio.2017.08.005openalex-snapshot
The bio in the ink: cartilage regeneration with bioprintable hydrogels and articular cartilage-derived progenitor cells
inferredcites →https://doi.org/10.1016/j.actbio.2019.07.035openalex-snapshot
(Photo-)crosslinkable gelatin derivatives for biofabrication applications
inferredcites →https://doi.org/10.1016/j.bioactmat.2021.05.011openalex-snapshot
Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges
inferredcites →https://doi.org/10.1016/j.biomaterials.2014.01.009openalex-snapshot
In vitro chondrogenesis and in vivo repair of osteochondral defect with human induced pluripotent stem cells
inferredcites →https://doi.org/10.1016/j.biomaterials.2014.10.020openalex-snapshot
Endochondral bone formation in gelatin methacrylamide hydrogel with embedded cartilage-derived matrix particles
inferredcites →https://doi.org/10.1016/j.biomaterials.2015.08.045openalex-snapshot
Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels
inferredcites →https://doi.org/10.1016/j.biomaterials.2021.120773openalex-snapshot
An in vitro Chondro-osteo-vascular Triphasic Model of the Osteochondral Complex
inferredcites →https://doi.org/10.1016/j.biomaterials.2021.120820openalex-snapshot
Patterned, organoid-based cartilaginous implants exhibit zone specific functionality forming osteochondral-like tissues in vivo
inferredcites →https://doi.org/10.1016/j.bone.2011.10.007openalex-snapshot
Tissue engineering approaches for osteoarthritis
inferredcites →https://doi.org/10.1016/j.bone.2020.115520openalex-snapshot
Developmental engineering of living implants for deep osteochondral joint surface defects
inferredcites →https://doi.org/10.1016/j.joca.2005.04.011openalex-snapshot
Variation of cell and matrix morphologies in articular cartilage among locations in the adult human knee
inferredcites →https://doi.org/10.1016/j.joca.2009.03.002openalex-snapshot
Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix
inferredcites →https://doi.org/10.1016/j.maturitas.2014.04.017openalex-snapshot
Chondrocyte and mesenchymal stem cell-based therapies for cartilage repair in osteoarthritis and related orthopaedic conditions
inferredcites →https://doi.org/10.1016/j.stemcr.2015.01.016openalex-snapshot
Generation of Scaffoldless Hyaline Cartilaginous Tissue from Human iPSCs
inferredcites →https://doi.org/10.1021/acs.biomac.7b00905openalex-snapshot
Cross-Linkable Gelatins with Superior Mechanical Properties Through Carboxylic Acid Modification: Increasing the Two-Photon Polymerization Potential
inferredcites →https://doi.org/10.1021/bm990017dopenalex-snapshot
Structural and Rheological Properties of Methacrylamide Modified Gelatin Hydrogels
inferredcites →https://doi.org/10.1038/nbt.3210openalex-snapshot
Generation of articular chondrocytes from human pluripotent stem cells
inferredcites →https://doi.org/10.1038/nprot.2016.037openalex-snapshot
Functionalization, preparation and use of cell-laden gelatin methacryloyl–based hydrogels as modular tissue culture platforms
inferredcites →https://doi.org/10.1038/s41598-017-00690-yopenalex-snapshot
Cartilage Tissue Engineering by the 3D Bioprinting of iPS Cells in a Nanocellulose/Alginate Bioink
inferredcites →https://doi.org/10.1039/c8tb02607fopenalex-snapshot
Effect of gelatin source and photoinitiator type on chondrocyte redifferentiation in gelatin methacryloyl-based tissue-engineered cartilage constructs
inferredcites →https://doi.org/10.1053/joca.2002.0801openalex-snapshot
Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects
inferredcites →https://doi.org/10.1053/joca.2002.0814openalex-snapshot
Quantitative structural organization of normal adult human articular cartilage
inferredcites →https://doi.org/10.1055/s-0040-1712944openalex-snapshot
Clinical Application of the Basic Science of Articular Cartilage Pathology and Treatment
inferredcites →https://doi.org/10.1080/10409230290771546openalex-snapshot
Biochemistry and Molecular Biology of Gelatinase B or Matrix Metalloproteinase-9 (MMP-9)
inferredcites →https://doi.org/10.1088/1758-5090/8/3/035002openalex-snapshot
3D bioprinting of BM-MSCs-loaded ECM biomimetic hydrogels for in vitro neocartilage formation
inferredcites →https://doi.org/10.1088/1758-5090/8/3/035003openalex-snapshot
Yield stress determines bioprintability of hydrogels based on gelatin-methacryloyl and gellan gum for cartilage bioprinting
inferredcites →https://doi.org/10.1088/1758-5090/ac1c99openalex-snapshot
Bio-3D printing iPSC-derived human chondrocytes for articular cartilage regeneration
inferredcites →https://doi.org/10.1089/ten.tea.2018.0133openalex-snapshot
Integration Capacity of Human Induced Pluripotent Stem Cell-Derived Cartilage
inferredcites →https://doi.org/10.1089/ten.tea.2020.0350openalex-snapshot
Recent Advances on Bioprinted Gelatin Methacrylate-Based Hydrogels for Tissue Repair
inferredcites →https://doi.org/10.1089/ten.teb.2014.0286openalex-snapshot
Chondrons and the Pericellular Matrix of Chondrocytes
inferredcites →https://doi.org/10.1091/mbc.e12-03-0172openalex-snapshot
ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation
inferredcites →https://doi.org/10.1096/fj.14-269720openalex-snapshot
Early induction of a prechondrogenic population allows efficient generation of stable chondrocytes from human induced pluripotent stem cells
inferredcites →https://doi.org/10.1097/jsa.0000000000000182openalex-snapshot
Articular Cartilage: Injury Pathways and Treatment Options
inferredcites →https://doi.org/10.1177/1941738115611350openalex-snapshot
Knee Articular Cartilage Repair and Restoration Techniques
inferredcites →https://doi.org/10.1177/1947603521993219openalex-snapshot
Algorithm for Treatment of Focal Cartilage Defects of the Knee: Classic and New Procedures
inferredcites →https://doi.org/10.1186/s13287-021-02580-7openalex-snapshot
Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects
inferredcites →https://doi.org/10.22203/ecm.v023a17openalex-snapshot
Influence of in vitro maturation of engineered cartilage on the outcome of osteochondral repair in a goat model
inferredcites →https://doi.org/10.22203/ecm.v027sa03openalex-snapshot
A vision on the future of articular cartilage repair
inferredcites →https://doi.org/10.22203/ecm.v036a08openalex-snapshot
Induced pluripotent stem cells for cartilage repair: current status and future perspectives
inferredcites →https://doi.org/10.3389/fbioe.2020.00373openalex-snapshot
Stiffness Matters: Fine-Tuned Hydrogel Elasticity Alters Chondrogenic Redifferentiation
inferredcites →https://doi.org/10.3389/fcell.2019.00270openalex-snapshot
Chondral Differentiation of Induced Pluripotent Stem Cells Without Progression Into the Endochondral Pathway
inferredcites →https://doi.org/10.3390/cells10010002openalex-snapshot
Stem Cells and Extrusion 3D Printing for Hyaline Cartilage Engineering
inferredcites →https://doi.org/10.3390/ma9100797openalex-snapshot
Synthesis and Characterization of Types A and B Gelatin Methacryloyl for Bioink Applications
inferredcites →https://doi.org/10.3390/polym8080269openalex-snapshot
3D Culture of Chondrocytes in Gelatin Hydrogels with Different Stiffness
inferredcites →https://doi.org/10.3390/polym9080309openalex-snapshot
Fabrication of Highly Crosslinked Gelatin Hydrogel and Its Influence on Chondrocyte Proliferation and Phenotype

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Strong, Elastic, Crosslinker-Free and All-Polysaccharide Double Network Hydrogels from Cellulose Nanofibrils and Aloe Vera
inferred← citeshttps://doi.org/10.1002/mabi.202400125openalex-snapshot
Nanostructured Biopolymer‐Based Constructs for Cartilage Regeneration: Fabrication Techniques and Perspectives
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inferred← citeshttps://doi.org/10.1039/d4bm00579aopenalex-snapshot
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inferred← citeshttps://doi.org/10.3389/fcell.2025.1593207openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/cells14080619openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/gels11090698openalex-snapshot
Novel GelMA/GelMA-AEMA Hydrogel Blend with Enhanced Printability as a Carrier for iPSC-Derived Chondrocytes In Vitro
inferred← citeshttps://doi.org/10.3390/polym14153023openalex-snapshot
Novel Trends in Hydrogel Development for Biomedical Applications: A Review
inferred← citeshttps://doi.org/10.53941/rmd.2025.100005openalex-snapshot
hiPSC-Driven Organoid Construction and Application Prospects
inferred← citeshttps://doi.org/10.64898/2026.03.31.715476openalex-snapshot
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