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Randomized clinical trial of short or long interval between neoadjuvant chemoradiotherapy and surgery for rectal cancer
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/1097-0142(19940601)73:11<2680::aid-cncr2820731105>3.0.co;2-copenalex-snapshot
Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma. Clinicopathologic correlations
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Long-term results of the Lyons R90-01 randomized trial of preoperative radiotherapy with delayed surgery and its effect on sphincter-saving surgery in rectal cancer
inferredcites →https://doi.org/10.1002/bjs.5506openalex-snapshot
Long-term results of a randomized trial comparing preoperative short-course radiotherapy with preoperative conventionally fractionated chemoradiation for rectal cancer
inferredcites →https://doi.org/10.1002/bjs.6377openalex-snapshot
Delaying surgery after neoadjuvant chemoradiotherapy for rectal cancer may reduce postoperative morbidity without compromising prognosis
inferredcites →https://doi.org/10.1002/bjs.6914openalex-snapshot
Interim analysis of the Stockholm III trial of preoperative radiotherapy regimens for rectal cancer
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Rectum-conserving surgery in the era of chemoradiotherapy
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Preoperative short-course radiotherapy with delayed surgery in primary rectal cancer
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Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer
inferredcites →https://doi.org/10.1002/bjs.8732openalex-snapshot
Critical appraisal of the ‘wait and see’ approach in rectal cancer for clinical complete responders after chemoradiation
inferredcites →https://doi.org/10.1002/bjs.9112openalex-snapshot
Optimal time interval between neoadjuvant chemoradiotherapy and surgery for rectal cancer
inferredcites →https://doi.org/10.1002/bjs.9811openalex-snapshot
Tumour regression in the randomized Stockholm III Trial of radiotherapy regimens for rectal cancer
inferredcites →https://doi.org/10.1016/j.ijrobp.2015.10.061openalex-snapshot
Pathologic Response, When Increased by Longer Interval, Is a Marker but Not the Cause of Good Prognosis in Rectal Cancer: 17-year Follow-up of the Lyon R90-01 Randomized Trial
inferredcites →https://doi.org/10.1016/j.jamcollsurg.2015.04.010openalex-snapshot
Extended Intervals after Neoadjuvant Therapy in Locally Advanced Rectal Cancer: The Key to Improved Tumor Response and Potential Organ Preservation
inferredcites →https://doi.org/10.1016/j.jamcollsurg.2015.12.017openalex-snapshot
Optimal Timing to Surgery after Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer
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Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data
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Optimal fractionation of preoperative radiotherapy and timing to surgery for rectal cancer (Stockholm III): a multicentre, randomised, non-blinded, phase 3, non-inferiority trial
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Results of a prospective randomised control 6 vs 12 trial: Is greater tumour downstaging observed on post treatment MRI if surgery is delayed to 12-weeks versus 6-weeks after completion of neoadjuvant chemoradiotherapy?
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Classification of Surgical Complications
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Oncologic Outcomes After Neoadjuvant Chemoradiation Followed by Curative Resection With Tumor-Specific Mesorectal Excision for Fixed Locally Advanced Rectal Cancer
inferredcites →https://doi.org/10.1097/dcr.0b013e31823f86cbopenalex-snapshot
Timing of Surgery Following Preoperative Therapy in Rectal Cancer
inferredcites →https://doi.org/10.1097/sla.0b013e3181b13ca2openalex-snapshot
The Clavien-Dindo Classification of Surgical Complications
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Predictive Factors of Pathologic Complete Response After Neoadjuvant Chemoradiation for Rectal Cancer
inferredcites →https://doi.org/10.1111/j.1463-1318.2005.00864.xopenalex-snapshot
Response to neoadjuvant therapy for rectal cancer: influence on long‐term results
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The effects of chemoradiotherapy on recurrence and survival in locally advanced rectal cancers with curative total mesorectal excision: a prospective, nonrandomized study
inferredcites →https://doi.org/10.1200/jco.1999.17.8.2396openalex-snapshot
Influence of the Interval Between Preoperative Radiation Therapy and Surgery on Downstaging and on the Rate of Sphincter-Sparing Surgery for Rectal Cancer: The Lyon R90-01 Randomized Trial
inferredcites →https://doi.org/10.1200/jco.2002.07.010openalex-snapshot
Macroscopic Evaluation of Rectal Cancer Resection Specimen: Clinical Significance of the Pathologist in Quality Control
inferredcites →https://doi.org/10.1200/jco.2012.42.9597openalex-snapshot
Randomized Trial of Short-Course Radiotherapy Versus Long-Course Chemoradiation Comparing Rates of Local Recurrence in Patients With T3 Rectal Cancer: Trans-Tasman Radiation Oncology Group Trial 01.04
inferredcites →https://doi.org/10.1200/jco.2016.67.6049openalex-snapshot
Effect of Interval (7 or 11 weeks) Between Neoadjuvant Radiochemotherapy and Surgery on Complete Pathologic Response in Rectal Cancer: A Multicenter, Randomized, Controlled Trial (GRECCAR-6)
inferredcites →https://doi.org/10.1245/s10434-008-9892-3openalex-snapshot
An Interval >7 Weeks between Neoadjuvant Therapy and Surgery Improves Pathologic Complete Response and Disease–Free Survival in Patients with Locally Advanced Rectal Cancer
inferredcites →https://doi.org/10.1245/s10434-010-1506-1openalex-snapshot
Pathologic Complete Response After Neoadjuvant Treatment for Rectal Cancer Decreases Distant Recurrence and Could Eradicate Local Recurrence
inferredcites →https://doi.org/10.1245/s10434-011-2209-yopenalex-snapshot
Complete Pathologic Response after Combined Modality Treatment for Rectal Cancer and Long-Term Survival: A Meta-Analysis
inferredcites →https://doi.org/10.1245/s10434-012-2327-1openalex-snapshot
Impact of Interval between Neoadjuvant Chemoradiotherapy and TME for Locally Advanced Rectal Cancer on Pathologic Response and Oncologic Outcome
inferredcites →https://doi.org/10.1245/s10434-015-4927-zopenalex-snapshot
Optimal Timing of Surgical Resection After Radiation in Locally Advanced Rectal Adenocarcinoma: An Analysis of the National Cancer Database
inferredcites →https://doi.org/10.5858/133.10.1539openalex-snapshot
Protocol for the Examination of Specimens From Patients With Primary Carcinoma of the Colon and Rectum
inferredcites →https://doi.org/10.5858/2008-132-1182-pfteosopenalex-snapshot
Protocol for the Examination of Specimens From Patients With Primary Carcinomas of the Colon and Rectum
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4596447openalex-extracted
Short-Term Results of the SONCAR Study: Optimized Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Patients - A Prospective Randomized Controlled Phase III Study
inferred← citeshttps://doi.org/10.1002/bjs.11220openalex-snapshot
Meta-analysis of the effect of extending the interval after long-course chemoradiotherapy before surgery in locally advanced rectal cancer
inferred← citeshttps://doi.org/10.1002/bjs.11574openalex-snapshot
Author response to: Should a minimum 8-week interval between preoperative radiotherapy and surgery become the standard of care? No, it shouldn't
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Total neoadjuvant therapy for locally advanced rectal cancer: the fuse is lit
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Time to surgery following neoadjuvant chemotherapy for breast cancer impacts residual cancer burden, recurrence, and survival
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Surgical timing after preoperative chemotherapy is associated with oncologic outcomes in resectable colorectal liver metastases
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Standard versus longer interval of radical resection after neoadjuvant chemoradiotherapy in locally advanced rectal cancer: A 20‐year single‐center experience & propensity‐score matching
inferred← citeshttps://doi.org/10.1002/jso.70263openalex-snapshot
Pelvic MRI Following Total Neoadjuvant Therapy for Rectal Cancer Poorly Predicts a Complete Clinical Response
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Short‐Term Results of the SONCAR Study: Optimized Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Patients
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Organerhalt beim Rektumkarzinom durch Radiochemotherapie
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Early response of total neoadjuvant therapy with regional deep hyperthermia for low-lying locally advanced rectal cancer: a single-center retrospective study
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Endoscopic and MRI response evaluation following neoadjuvant treatment for rectal cancer: a pictorial review with matched MRI, endoscopic, and pathologic examples
inferred← citeshttps://doi.org/10.1007/s00330-019-06638-2openalex-snapshot
Value of combined multiparametric MRI and FDG-PET/CT to identify well-responding rectal cancer patients before the start of neoadjuvant chemoradiation
inferred← citeshttps://doi.org/10.1007/s00384-022-04122-wopenalex-snapshot
Does a long interval between neoadjuvant chemoradiotherapy and surgery benefit the clinical outcomes of locally advanced rectal cancer? A systematic review and meta analyses
inferred← citeshttps://doi.org/10.1007/s00384-023-04457-yopenalex-snapshot
Determining the optimal interval between neoadjuvant radiochemotherapy and surgery in rectal cancer: a retrospective cohort study
inferred← citeshttps://doi.org/10.1007/s00384-026-05112-yopenalex-snapshot
Chemoradiotherapy and transanal endoscopic surgery versus transanal endoscopic surgery alone in T1N0M0 rectal cancer: a multicenter, randomized, controlled, phase III clinical trial (TAUTEM-T1 study)
inferred← citeshttps://doi.org/10.1007/s00384-026-05144-4openalex-snapshot
Effect of prolonged interval between neoadjuvant chemoradiotherapy and surgery on pathological and oncological outcomes in locally advanced rectal cancer: a randomized controlled trial
inferred← citeshttps://doi.org/10.1007/s00595-024-02988-7openalex-snapshot
Risk factors for anastomotic leakage in rectal cancer surgery reflecting current practices
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Organerhaltende Konzepte durch Radiochemotherapie: Wo stehen wir?
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Organerhalt beim Rektumkarzinom
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Organ Preservation in Rectal Cancer
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Gastrointestinal Malignancies and the COVID-19 Pandemic: Evidence-Based Triage to Surgery
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Delaying surgery by more than 10 weeks after long-course neoadjuvant radiotherapy in locally advanced rectal cancer patients improves pathologic complete response
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Surgical timing following neoadjuvant chemotherapy for breast cancer affects postoperative complication rates
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Impact of prolonged interval between neoadjuvant chemoradiotherapy and surgery on outcomes in locally advanced rectal cancer: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.clcc.2020.07.009openalex-snapshot
A Comprehensive Review of Randomized Clinical Trials Shaping the Landscape of Rectal Cancer Therapy
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2023.103927openalex-snapshot
A systematic review and network meta-analysis of randomised controlled trials comparing neoadjuvant treatment strategies for stage II and III rectal cancer
inferred← citeshttps://doi.org/10.1016/j.ctrv.2020.101964openalex-snapshot
How to measure tumour response in rectal cancer? An explanation of discrepancies and suggestions for improvement
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Total neoadjuvant therapy for rectal cancer: Making sense of the results from the RAPIDO and PRODIGE 23 trials
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Optimal timing of surgery following breast cancer neoadjuvant chemotherapy: A systematic review and meta-analysis
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Improved response rate in patients with prognostically poor locally advanced rectal cancer after treatment with induction chemotherapy and chemoradiotherapy when compared with chemoradiotherapy alone: A matched case-control study
inferred← citeshttps://doi.org/10.1016/j.prro.2020.04.002openalex-snapshot
Radiation Therapy for Cervical Cancer: Executive Summary of an ASTRO Clinical Practice Guideline
inferred← citeshttps://doi.org/10.1016/j.prro.2020.08.004openalex-snapshot
Radiation Therapy for Rectal Cancer: Executive Summary of an ASTRO Clinical Practice Guideline
inferred← citeshttps://doi.org/10.1016/j.prro.2024.11.003openalex-snapshot
Radiation Therapy for Rectal Cancer: An ASTRO Clinical Practice Guideline Focused Update
inferred← citeshttps://doi.org/10.1016/j.prro.2024.11.008openalex-snapshot
Reirradiation in the Management of Locally Recurrent Rectal Adenocarcinoma
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Deep regional hyperthermia with preoperative radiochemotherapy in locally advanced rectal cancer, a prospective phase II trial
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Papel de la resonancia magnética en la evaluación del cáncer de recto tras terapia neoadyuvante
inferred← citeshttps://doi.org/10.1016/j.rxeng.2025.101625openalex-snapshot
Role of magnetic resonance imaging in the evaluation of rectal cancer after neoadjuvant therapy
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Advances in Radiotherapy for Rectal Cancer
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Prolonged interval to surgery following neoadjuvant chemoradiotherapy in locally advanced rectal cancer: A meta-analysis of randomized controlled trials
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Watch-and-wait Management for Rectal Cancer After Clinical Complete Response to Neoadjuvant Therapy
inferred← citeshttps://doi.org/10.1016/s1470-2045(20)30024-3openalex-snapshot
Outcome measures in multimodal rectal cancer trials
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Neoadjuvant chemoradiation with or without PD-1 blockade in locally advanced rectal cancer: a randomized phase 2 trial
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Machine learning for predicting pathological complete response in patients with locally advanced rectal cancer after neoadjuvant chemoradiotherapy
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Identifying the long-term survival beneficiary of preoperative radiotherapy for rectal cancer in the TME era
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Clinical Analysis of the Efficacy and Safety of Different Neoadjuvant Strategies in the Treatment of Locally Advanced Rectal Cancer
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Long-Term Oncological Outcomes for Locally Advanced Rectal Cancer Patients with Pathological Complete Response After Neoadjuvant Chemoradiotherapy: A Turkish Oncology Group Study
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Raddeanin A Inhibits Colorectal Cancer Growth and Ameliorates Oxaliplatin Resistance Through the WNT/β-Catenin Signaling Pathway
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Prevalence of nodal involvement in rectal cancer after chemoradiotherapy
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Total neoadjuvant therapy versus standard neoadjuvant treatment strategies for the management of locally advanced rectal cancer: network meta-analysis of randomized clinical trials
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Effect of interval between neoadjuvant chemoradiotherapy and surgery on disease recurrence and survival in rectal cancer: long-term results of a randomized clinical trial
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Total Neoadjuvant Therapy Significantly Increases Complete Clinical Response
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Final Results of the GRECCAR-6 Trial on Waiting Period Following Neoadjuvant Radiochemotherapy for Locally Advanced Rectal Cancer: 5 Years of Follow-up
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The Deepest Extent of Acellular Mucin Pools in Resected Locally Advanced Rectal Cancer With Pathological Complete Response After Preoperative Chemoradiotherapy
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Current status of total neoadjuvant therapy for locally advanced rectal cancer
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Randomized controlled trial of 8 weeks’ vs 12 weeks’ interval between neoadjuvant chemoradiotherapy and surgery for locally advanced rectal cancer
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Presence and clinical significance of acellular mucin pools in resected rectal cancer with pathological complete response after pre‐operative chemoradiotherapy
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Efficacy and Safety of Preoperative Radiotherapy Versus Chemoradiotherapy in Advanced Rectal Cancer: A Meta-analysis of Randomized Controlled Trials
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The Impact of Gastric Anatomical Subdivisions on the Response to Neoadjuvant Chemotherapy in Gastric Cancer
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Clinical significance of neoadjuvant chemotherapy for locally advanced colorectal cancer patients with deficient mismatch repair: possibly residual value in the era of immunotherapy
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Dose–time fractionation schedules of preoperative radiotherapy and timing to surgery for rectal cancer
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Short-course radiation followed by mFOLFOX-6 plus avelumab for locally-advanced rectal adenocarcinoma
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Optimal timing of surgery for gastric cancer after neoadjuvant chemotherapy: a systematic review and meta-analysis
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Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: Induction or Consolidation Chemotherapy?
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Application and Advances of Neoadjuvant Radiotherapy in Rectal Cancer
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Temporal determinants of tumour response to neoadjuvant rectal radiotherapy
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Transanal Surgery for benign tumor or early rectal cancer: state of the art and future prospects of the surgeon
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Do the Locally Advanced Rectal Cancer Patients Enjoy Long-term Survival Benefit From the Radiation-based Neoadjuvant Treatments in the Total Mesorectal Excision Era: a Population-based Analysis
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Multimodality and multi-parametric imaging in abdominal oncology
inferred← citeshttps://doi.org/10.26481/dis.20220928evopenalex-snapshot
Locally advanced and locally recurrent rectal cancer
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¿Debemos incrementar el intervalo entre neoadyuvancia y cirugía en el cáncer de recto para lograr una respuesta patológica completa?: Revisión sistemática de la literatura
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Neoadjuvant intermediate-course versus long-course chemoradiotherapy in T3-4/N0+ rectal cancer: Istanbul R-02 phase II randomized study
inferred← citeshttps://doi.org/10.3322/caac.21661openalex-snapshot
Locally advanced rectal adenocarcinoma: Treatment sequences, intensification, and rectal organ preservation
inferred← citeshttps://doi.org/10.33612/diss.789782613openalex-snapshot
Optimizing the treatment of locally advanced and recurrent rectal cancer
inferred← citeshttps://doi.org/10.3389/fonc.2020.613988openalex-snapshot
Optimal Timing to Surgery After Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer
inferred← citeshttps://doi.org/10.3389/fonc.2022.953790openalex-snapshot
Prolonged neoadjuvant chemotherapy without radiation versus total neoadjuvant therapy for locally advanced rectal cancer: A propensity score matched study
inferred← citeshttps://doi.org/10.3389/fonc.2024.1477510openalex-snapshot
Nonoperative management of rectal cancer
inferred← citeshttps://doi.org/10.3390/cancers16010026openalex-snapshot
Quality of Surgical Outcome Reporting in Randomised Clinical Trials of Multimodal Rectal Cancer Treatment: A Systematic Review
inferred← citeshttps://doi.org/10.3390/cancers16162807openalex-snapshot
Journey through the Decades: The Evolution in Treatment and Shared Decision Making for Locally Advanced Rectal Cancer
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Updates of Risk Factors for Anastomotic Leakage after Colorectal Surgery
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Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: How to Select the Most Suitable?
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Impact of interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer patients
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Restaging rectal cancer following neoadjuvant chemoradiotherapy
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Neoadjuvant Radiotherapy in Rectal Cancer: A Single Center Experience
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Robotic Rectal Resection for Rectal Cancer: State of the Art
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