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Concentration profiles of cocaine, pyrolytic methyl ecgonidine and thirteen metabolites in human blood and urine: determination by gas chromatography–mass spectrometry

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1096-9888(199906)34:6<651::aid-jms817>3.0.co;2-mopenalex-snapshot
Electron ionization mass fragmentometric detection of urinary ecgonidine, a hydrolytic product of methylecgonidine, as an indicator of smoking cocaine
inferredcites →https://doi.org/10.1016/0024-3205(94)00410-topenalex-snapshot
Pulmonary effects of the cocaine pyrolysis product, methylecgonidine, in guinea pigs
inferredcites →https://doi.org/10.1016/0024-3205(94)00496-fopenalex-snapshot
Characterization of the binding of [125I]L-735,286: A new nonpeptide angiotensin II AT1 receptor radioligand
inferredcites →https://doi.org/10.1016/0024-3205(95)00267-aopenalex-snapshot
Effect of endothelin-1 on arterial response to Bay K 8644
inferredcites →https://doi.org/10.1016/0024-3205(95)02113-wopenalex-snapshot
Effects of Methylecgonidine on acetylcholine-induced bronchoconstriction and indicators of lung injury in guinea pigs
inferredcites →https://doi.org/10.1016/0024-3205(95)02166-gopenalex-snapshot
Effects of cocaine, cocaine metabolites and cocaine pyrolysis products on the hindbrain cardiac and respiratory centers of the rabbit ag
inferredcites →https://doi.org/10.1016/s0892-0362(00)00092-1openalex-snapshot
Neurobehavioral outcomes of cocaine-exposed infants
inferredcites →https://doi.org/10.1037/e496372006-002openalex-snapshot
Current Patterns of Drug Abuse That Involve Smoking
inferredcites →https://doi.org/10.1037/e496372006-004openalex-snapshot
The Pharmacology of Cocaine Smoking in Humans
inferredcites →https://doi.org/10.1037/e496912006-010openalex-snapshot
Characteristics of Cocaine Abusers Presenting for Treatment
inferredcites →https://doi.org/10.1038/clpt.1982.189openalex-snapshot
Free-base cocaine smoking
inferredcites →https://doi.org/10.1093/clinchem/37.12.2160openalex-snapshot
Passive Inhalation of Cocaine
inferredcites →https://doi.org/10.1093/clinchem/47.6.1040openalex-snapshot
Examination of Postmortem Fluids and Tissues for the Presence of Methylecgonidine, Ecgonidine, Cocaine, and Benzoylecgonine Using Solid-Phase Extraction and Gas Chromatography–Mass Spectrometry2
inferredcites →https://doi.org/10.1093/jat/11.2.81openalex-snapshot
Urinary Excretion of Cocaine and Benzoylecgonine Following Oral Ingestion in a Single Subject
inferredcites →https://doi.org/10.1093/jat/13.3.158openalex-snapshot
Pyrolysis and Volatilization of Cocaine
inferredcites →https://doi.org/10.1093/jat/14.6.383openalex-snapshot
On the Dermal Absorption of Cocaine
inferredcites →https://doi.org/10.1093/jat/15.1.46openalex-snapshot
Urinalysis and Casual Handling of Marijuana and Cocaine
inferredcites →https://doi.org/10.1093/jat/15.3.105openalex-snapshot
Inhalation Efficiency of Free-Base Cocaine by Pyrolysis of ‘Crack’ and Cocaine Hydrochloride
inferredcites →https://doi.org/10.1093/jat/17.6.378openalex-snapshot
Effect of Freezing on the Concentration of Drugs of Abuse in Urine
inferredcites →https://doi.org/10.1097/00005344-199709000-00013openalex-snapshot
Negative Inotropic Effect of Methylecgonidine, a Major Product of Cocaine Base Pyrolysis, on Ferret and Human Myocardium
inferredcites →https://doi.org/10.1152/ajpcell.1997.273.3.c893openalex-snapshot
PKA-mediated phosphorylation and inhibition of Na(+)-K(+)-ATPase in response to beta-adrenergic hormone
inferredcites →https://doi.org/10.1152/ajpheart.1997.273.2.h893openalex-snapshot
Effect of cocaine and methylecgonidine on intracellular Ca2+ and myocardial contraction in cardiac myocytes
inferredcites →https://doi.org/10.1176/ps.37.12.1229openalex-snapshot
Recent Trends in Cocaine Abuse in a VA Psychiatric Population
inferredcites →https://doi.org/10.2307/2285423openalex-snapshot
Biostatistical Analysis.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4835952openalex-extracted
Liquid Crystal Aptamer-Based Sensor with a Functionalised Amphiphilic Block Copolymer for the Detection of M-Hydroxy Cocaine
inferred← citeshttps://doi.org/10.1002/bmc.2775openalex-snapshot
Simultaneous quantification of morphine and cocaine in hair samples from drug addicts by GC‐EI/MS
inferred← citeshttps://doi.org/10.1002/dta.2317openalex-snapshot
Determination of hydroxy metabolites of cocaine in hair samples for proof of consumption
inferred← citeshttps://doi.org/10.1002/dta.2547openalex-snapshot
Optimization and validation of simultaneous analyses of ecgonine, cocaine, and seven metabolites in human urine by gas chromatography–mass spectrometry using a one‐step solid‐phase extraction
inferred← citeshttps://doi.org/10.1002/elps.201100410openalex-snapshot
Simultaneous analysis of cocaine and its metabolites in urine by capillary electrophoresis–electrospray mass spectrometry using a pressurized liquid junction nanoflow interface
inferred← citeshttps://doi.org/10.1002/jms.954openalex-snapshot
Current literature in mass spectrometry
inferred← citeshttps://doi.org/10.1002/mas.20168openalex-snapshot
Mass spectrometric analysis of illicit drugs in wastewater and surface water
inferred← citeshttps://doi.org/10.1007/978-1-61779-934-1_8openalex-snapshot
Cocaine and Metabolites by LC-MS/MS
inferred← citeshttps://doi.org/10.1007/s00216-007-1228-9openalex-snapshot
Bioanalytical procedures for monitoring in utero drug exposure
inferred← citeshttps://doi.org/10.1007/s00216-007-1271-6openalex-snapshot
Bioanalytical procedures for determination of drugs of abuse in blood
inferred← citeshttps://doi.org/10.1007/s00216-010-4191-9openalex-snapshot
Quantification of drugs of abuse in municipal wastewater via SPE and direct injection liquid chromatography mass spectrometry
inferred← citeshttps://doi.org/10.1007/s00216-011-5553-7openalex-snapshot
A hydrolysis procedure for the analysis of total cocaine residues in wastewater
inferred← citeshttps://doi.org/10.1007/s00216-013-7417-9openalex-snapshot
Determination of ecgonine and seven other cocaine metabolites in human urine and whole blood by ultra-high-pressure liquid chromatography–quadrupole time-of-flight mass spectrometry
inferred← citeshttps://doi.org/10.1007/s00216-016-9354-xopenalex-snapshot
Analysis of cocaine and metabolites in hair: validation and application of measurement of hydroxycocaine metabolites as evidence of cocaine ingestion
inferred← citeshttps://doi.org/10.1007/s11356-013-2403-5openalex-snapshot
Stability of cocaine and its metabolites in municipal wastewater – the case for using metabolite consolidation to monitor cocaine utilization
inferred← citeshttps://doi.org/10.1007/s11356-018-2864-7openalex-snapshot
Wastewater-based epidemiology in low Human Development Index states: bias in consumption monitoring of illicit drugs
inferred← citeshttps://doi.org/10.1007/s11419-020-00545-8openalex-snapshot
Use of injection-port derivatization for the analysis of cocaine and its metabolites in urine by gas chromatography–tandem mass spectrometry
inferred← citeshttps://doi.org/10.1016/b978-0-12-803750-8.00006-3openalex-snapshot
Cocaine Postmortem Distribution in Brain
inferred← citeshttps://doi.org/10.1016/b978-0-12-815607-0.00015-0openalex-snapshot
Confirmation Methods for SAMHSA Drugs and Other Commonly Abused Drugs
inferred← citeshttps://doi.org/10.1016/b978-0-12-815607-0.00017-4openalex-snapshot
Cocaine, Crack Cocaine, and Ethanol
inferred← citeshttps://doi.org/10.1016/b978-1-4160-6164-9.00035-4openalex-snapshot
Clinical Toxicology
inferred← citeshttps://doi.org/10.1016/b978-2-294-71561-7.00012-1openalex-snapshot
Cocaïne
inferred← citeshttps://doi.org/10.1016/j.chroma.2011.01.060openalex-snapshot
Multi-residue analysis of drugs of abuse in wastewater and surface water by solid-phase extraction and liquid chromatography–positive electrospray ionisation tandem mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.clinbiochem.2016.01.019openalex-snapshot
Cocaine and crack cocaine abuse by pregnant or lactating mothers and analysis of its biomarkers in meconium and breast milk by LC–MS—A review
inferred← citeshttps://doi.org/10.1016/j.envint.2011.05.009openalex-snapshot
Refined sewer epidemiology mass balances and their application to heroin, cocaine and ecstasy
inferred← citeshttps://doi.org/10.1016/j.forsciint.2018.05.030openalex-snapshot
Determination of cocaine, metabolites and a crack cocaine biomarker in whole blood by liquid–liquid extraction and UHPLC–MS/MS
inferred← citeshttps://doi.org/10.1016/j.jchromb.2006.02.002openalex-snapshot
Simultaneous quantification of methamphetamine, cocaine, codeine, and metabolites in skin by positive chemical ionization gas chromatography–mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.jchromb.2010.03.007openalex-snapshot
Tropane alkaloid analysis by chromatographic and electrophoretic techniques: An update
inferred← citeshttps://doi.org/10.1016/j.jchromb.2010.09.010openalex-snapshot
Development and validation of a gas chromatography/ion trap-mass spectrometry method for simultaneous quantification of cocaine and its metabolites benzoylecgonine and norcocaine: Application to the study of cocaine metabolism in human primary cultured renal cells
inferred← citeshttps://doi.org/10.1016/j.jchromb.2014.04.052openalex-snapshot
Liquid chromatography/tandem mass spectrometry method for simultaneous determination of cocaine and its metabolite (−)ecgonine methyl ester in human acidified stabilized plasma samples
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2026.142904openalex-snapshot
Oxic and suboxic zones along hyporheic flow paths contribute to the attenuation of trace organic contaminants, as revealed by suspect screening
inferred← citeshttps://doi.org/10.1016/j.jpba.2014.10.026openalex-snapshot
Determination of cocaine/crack biomarkers in colostrum by LC–MS following protein precipitation
inferred← citeshttps://doi.org/10.1016/j.jpba.2019.04.028openalex-snapshot
Analysis of hydroxy-cocaine metabolites as evidence of cocaine consumption: Identification by parent ion search and quantitation by UHPLC-MS/MS in hair
inferred← citeshttps://doi.org/10.1016/j.microc.2025.113595openalex-snapshot
Liquid crystal aptamer-based sensor with a functionalized amphiphilic block copolymer for the detection of m-hydroxy cocaine
inferred← citeshttps://doi.org/10.1016/j.tox.2016.04.009openalex-snapshot
Anhydroecgonine methyl ester, a cocaine pyrolysis product, may contribute to cocaine behavioral sensitization
inferred← citeshttps://doi.org/10.1016/j.toxrep.2019.11.001openalex-snapshot
Anhydroecgonine methyl ester (AEME), a cocaine pyrolysis product, impairs glutathione-related enzymes response and increases lipid peroxidation in the hippocampal cell culture
inferred← citeshttps://doi.org/10.1016/j.vascn.2017.04.003openalex-snapshot
Simultaneous determination of cocaine/crack and its metabolites in oral fluid, urine and plasma by liquid chromatography-mass spectrometry and its application in drug users
inferred← citeshttps://doi.org/10.1016/j.watres.2011.07.017openalex-snapshot
Identification of cocaine and its metabolites in urban wastewater and comparison with the human excretion profile in urine
inferred← citeshttps://doi.org/10.1016/s1567-7192(06)06002-5openalex-snapshot
Chapter 2 Current methods for the separation and analysis of cocaine analytes
inferred← citeshttps://doi.org/10.1021/bk-2019-1319.ch003openalex-snapshot
GC-MS Methods for Monitoring Illicit Drug Biomarkers in Wastewater: A Critical Review
inferred← citeshttps://doi.org/10.1038/srep17555openalex-snapshot
M1 and M3 muscarinic receptors may play a role in the neurotoxicity of anhydroecgonine methyl ester, a cocaine pyrolysis product
inferred← citeshttps://doi.org/10.1039/c4ay01034eopenalex-snapshot
Differentiating crack cocaine from regular cocaine in whole blood samples in drugs and driving cases
inferred← citeshttps://doi.org/10.1093/jat/30.8.501openalex-snapshot
Major and Minor Metabolites of Cocaine in Human Plasma following Controlled Subcutaneous Cocaine Administration
inferred← citeshttps://doi.org/10.1093/jat/31.5.237openalex-snapshot
Modern Instrumental Methods in Forensic Toxicology
inferred← citeshttps://doi.org/10.1093/jat/31.8.462openalex-snapshot
Cocaine and Metabolites Urinary Excretion after Controlled Smoked Administration*
inferred← citeshttps://doi.org/10.1093/jat/33.8.447openalex-snapshot
Sensitive Method For Detection Of Cocaine And Associated Analytes By Liquid Chromatography-Tandem Mass Spectrometry In Urine
inferred← citeshttps://doi.org/10.1093/jat/34.1.17openalex-snapshot
Simultaneous Liquid Chromatography-Mass Spectrometry Quantification of Urinary Opiates, Cocaine, and Metabolites in Opiate-Dependent Pregnant Women in Methadone-Maintenance Treatment
inferred← citeshttps://doi.org/10.1093/jat/34.2.57openalex-snapshot
Urinary Excretion of Ecgonine and Five Other Cocaine Metabolites Following Controlled Oral, Intravenous, Intranasal, and Smoked Administration of Cocaine
inferred← citeshttps://doi.org/10.1093/jat/bkaf106openalex-snapshot
Pre-analytical stability of drugs of abuse in urine for confirmatory testing: a systematic review
inferred← citeshttps://doi.org/10.1093/jat/bkv035openalex-snapshot
Analysis of Urinary Biomarkers for Smoking Crack Cocaine: Results of a Danish Laboratory Study
inferred← citeshttps://doi.org/10.1093/jat/bkx085openalex-snapshot
Comparison of Cocaine/Crack Biomarkers Concentrations in Oral Fluid, Urine and Plasma Simultaneously Collected From Drug Users
inferred← citeshttps://doi.org/10.1093/jat/bky007openalex-snapshot
Bioavailability and Pharmacokinetics of Oral Cocaine in Humans
inferred← citeshttps://doi.org/10.1093/jat/bkz022openalex-snapshot
Cocaine Hydroxy Metabolites in Hair: Indicators for Cocaine Use Versus External Contamination☆
inferred← citeshttps://doi.org/10.1093/toxsci/kfs140openalex-snapshot
Neurotoxicity of Anhydroecgonine Methyl Ester, a Crack Cocaine Pyrolysis Product
inferred← citeshttps://doi.org/10.1097/01.ftd.0000211812.27558.6eopenalex-snapshot
Toxicokinetics of Drugs of Abuse: Current Knowledge of the Isoenzymes Involved in the Human Metabolism of Tetrahydrocannabinol, Cocaine, Heroin, Morphine, and Codeine
inferred← citeshttps://doi.org/10.11606/d.5.2015.tde-27102015-112239openalex-snapshot
Estudos epigenéticos em dependentes de crack e cocaína: investigação da metilação global do genoma
inferred← citeshttps://doi.org/10.11606/d.60.2018.tde-11102018-152050openalex-snapshot
Investigação de adulterantes em amostras de cocaína apreendidas na região de Araçatuba no período de 2014 a 2015
inferred← citeshttps://doi.org/10.1196/annals.1384.037openalex-snapshot
Interpretation of Oral Fluid Tests for Drugs of Abuse
inferred← citeshttps://doi.org/10.1201/b18962-2openalex-snapshot
Cocaine
inferred← citeshttps://doi.org/10.1201/ebk1439826584-c7openalex-snapshot
Toxicology
inferred← citeshttps://doi.org/10.15260/rbc.v8i1.298openalex-snapshot
Investigação de adulterantes em amostras de cocaína apreendidas na região de Araçatuba no período de 2014 a 2015
inferred← citeshttps://doi.org/10.25148/etd.fi13040402openalex-snapshot
Covalent Protein Adduction by Drugs of Abuse
inferred← citeshttps://doi.org/10.4155/bio.15.127openalex-snapshot
Cocaine and Metabolite Concentrations in DBS and Venous Blood After Controlled Intravenous Cocaine Administration
inferred← citeshttps://doi.org/10.47749/t/unicamp.2015.952501openalex-snapshot
Determinação de cocaína e metabólitos em amostras de urina de usuários da droga e em amostras ambientais
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