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Impact of aeration strategy on CHO cell performance during antibody production
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1097-0290(19990220)62:4<468::aid-bit10>3.0.co;2-nopenalex-snapshot
Cell death from bursting bubbles: Role of cell attachment to rising bubbles in sparged reactors
inferredcites →https://doi.org/10.1002/bit.21029openalex-snapshot
Shear stress analysis of mammalian cell suspensions for prediction of industrial centrifugation and its verification
inferredcites →https://doi.org/10.1002/bit.21840openalex-snapshot
The fate of Pluronic F‐68 in chondrocytes and CHO cells
inferredcites →https://doi.org/10.1002/bit.22339openalex-snapshot
Physiological responses of CHO cells to repetitive hydrodynamic stress
inferredcites →https://doi.org/10.1002/bit.22393openalex-snapshot
Ultra scale‐down prediction using microwell technology of the industrial scale clarification characteristics by centrifugation of mammalian cell broths
inferredcites →https://doi.org/10.1002/bit.22790openalex-snapshot
Rapid whole monoclonal antibody analysis by mass spectrometry: An Ultra scale‐down study of the effect of harvesting by centrifugation on the post‐translational modification profile
inferredcites →https://doi.org/10.1002/bit.260100607openalex-snapshot
The cultivation of animal cells at controlled dissolved oxygen partial pressure
inferredcites →https://doi.org/10.1002/bit.260360906openalex-snapshot
The role of the plasma membrane fluidity on the shear sensitivity of hybridomas grown under hydrodynamic stress
inferredcites →https://doi.org/10.1002/bit.260380209openalex-snapshot
Protection mechanisms of freely suspended animal cells (CRL 8018) from fluid‐mechanical injury. Viscometric and bioreactor studies using serum, pluronic F68 and polyethylene glycol
inferredcites →https://doi.org/10.1002/bit.260400814openalex-snapshot
Damaging agitation intensities increase DNA synthesis rate and alter cell‐cycle phase distributions of CHO cells
inferredcites →https://doi.org/10.1002/bit.260440910openalex-snapshot
Flow parameters associated with hydrodynamic cell injury
inferredcites →https://doi.org/10.1002/bit.260450602openalex-snapshot
Death mechanisms of animal cells in conditions of intensive agitation
inferredcites →https://doi.org/10.1002/bit.260470403openalex-snapshot
Interfacial properties of cell culture media with cell‐protecting additives
inferredcites →https://doi.org/10.1002/btpr.503openalex-snapshot
Effect of surfactant pluronic F‐68 on CHO cell growth, metabolism, production, and glycosylation of human recombinant IFN‐γ in mild operating conditions
inferredcites →https://doi.org/10.1002/btpr.8openalex-snapshot
High yields of monomeric recombinant β‐interferon from macroporous microcarrier cultures under hypothermic conditions
inferredcites →https://doi.org/10.1002/cyto.990200209openalex-snapshot
A new flow cytometric method for discrimination of apoptotic cells and detection of their cell cycle specificity through staining of F‐actin and DNA
inferredcites →https://doi.org/10.1006/abio.1995.1468openalex-snapshot
Nonselective and Efficient Fluorescent Labeling of Glycans Using 2-Amino Benzamide and Anthranilic Acid
inferredcites →https://doi.org/10.1007/0-306-46875-1openalex-snapshot
Animal Cell Technology: Products from Cells, Cells as Products
inferredcites →https://doi.org/10.1007/bf00127978openalex-snapshot
Enhanced specific antibody productivity of hybridomas resulting from hyperosmotic stress is cell line-specific
inferredcites →https://doi.org/10.1007/bf00353919openalex-snapshot
Engineering challenges in high density cell culture systems
inferredcites →https://doi.org/10.1007/s002320001034openalex-snapshot
Partners in Protection: Interdependence of Cytoskeleton and Plasma Membrane in Adaptations to Applied Forces
inferredcites →https://doi.org/10.1007/s00253-005-1980-8openalex-snapshot
Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals
inferredcites →https://doi.org/10.1007/s00449-003-0328-yopenalex-snapshot
Performance prediction of industrial centrifuges using scale-down models
inferredcites →https://doi.org/10.1007/s00449-011-0532-0openalex-snapshot
A comprehensive comparison of mixing, mass transfer, Chinese hamster ovary cell growth, and antibody production using Rushton turbine and marine impellers
inferredcites →https://doi.org/10.1007/s10616-006-9005-8openalex-snapshot
Reactor Engineering in Large Scale Animal Cell Culture
inferredcites →https://doi.org/10.1007/s10616-006-9008-5openalex-snapshot
Regulating apoptosis in mammalian cell cultures
inferredcites →https://doi.org/10.1007/s10616-011-9368-3openalex-snapshot
The potential of hydrodynamic damage to animal cells of industrial relevance: current understanding
inferredcites →https://doi.org/10.1016/0141-0229(92)90081-xopenalex-snapshot
Effect of Pluronic F-68 on the mechanical properties of mammalian cells
inferredcites →https://doi.org/10.1016/0167-7799(91)90102-nopenalex-snapshot
Media additives for protecting freely suspended animal cells against agitation and aeration damage
inferredcites →https://doi.org/10.1016/j.biotechadv.2010.02.003openalex-snapshot
Strategies for the enhancement of recombinant protein production from mammalian cells by growth arrest
inferredcites →https://doi.org/10.1016/j.jbiomech.2009.09.003openalex-snapshot
Mechanics of the F-actin cytoskeleton
inferredcites →https://doi.org/10.1016/s0167-7799(00)01474-8openalex-snapshot
Animal-cell damage in sparged bioreactors
inferredcites →https://doi.org/10.1021/bp00005a011openalex-snapshot
Protective Effect of Methylcellulose and Other Polymers on Insect Cells Subjected to Laminar Shear Stress
inferredcites →https://doi.org/10.1021/bp00008a010openalex-snapshot
Microscopic Visualization of Insect Cell‐Bubble Interactions. II: The Bubble Film and Bubble Rupture
inferredcites →https://doi.org/10.1021/bp025780popenalex-snapshot
Experimental and Theoretical Analysis of Tubular Membrane Aeration for Mammalian Cell Bioreactors
inferredcites →https://doi.org/10.1021/bp049815sopenalex-snapshot
Effects of Elevated pCO2 and Osmolality on Growth of CHO Cells and Production of Antibody-Fusion Protein B1: A Case Study
inferredcites →https://doi.org/10.1021/bp070117sopenalex-snapshot
Very Large Scale Monoclonal Antibody Purification: The Case for Conventional Unit Operations
inferredcites →https://doi.org/10.1038/nature08908openalex-snapshot
Cell mechanics and the cytoskeleton
inferredcites →https://doi.org/10.1038/nrm1682openalex-snapshot
The actin cytoskeleton: a key regulator of apoptosis and ageing?
inferredcites →https://doi.org/10.1093/glycob/cwp079openalex-snapshot
Optimal and consistent protein glycosylation in mammalian cell culture
inferredcites →https://doi.org/10.1093/ndt/gfl476openalex-snapshot
Immunogenicity of biopharmaceuticals
inferredcites →https://doi.org/10.1099/00221287-5-1-167openalex-snapshot
The Measurement of the Aeration of Culture Media
inferredcites →https://doi.org/10.1242/jcs.100.1.187openalex-snapshot
Quantitation of actin polymerization in two human fibroblast sub-types responding to mechanical stretching
inferredcites →https://doi.org/10.1242/jcs.111.12.1649openalex-snapshot
Actin dynamics in living mammalian cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4661299openalex-extracted
Effect of Backwash as a Strategy for Biofouling Control in A Submerged Ceramic Membrane Bioreactor for High-Density Cultivations: Process Optimization and Fouling Mechanism at Pilot Scale
inferred← citeshttps://doi.org/10.1002/amp2.10106openalex-snapshot
Process analytical technologies in cell therapy manufacturing: State‐of‐the‐art and future directions
inferred← citeshttps://doi.org/10.1002/biot.201400294openalex-snapshot
Representative mammalian cell culture test materials for assessment of primary recovery technologies: A rapid method with industrial applicability
inferred← citeshttps://doi.org/10.1002/biot.202100360openalex-snapshot
Equal mixing time enables scale‐down and optimization of a CHO cell culture process using a shaken microbioreactor system
inferred← citeshttps://doi.org/10.1002/biot.202300495openalex-snapshot
Exploring metabolic responses and pathway changes in CHO‐K1 cells under varied aeration conditions and copper supplementations using 1H NMR‐based metabolomics
inferred← citeshttps://doi.org/10.1002/btpr.1726openalex-snapshot
Differential response in downstream processing of CHO cells grown under mild hypothermic conditions
inferred← citeshttps://doi.org/10.1002/btpr.2155openalex-snapshot
Fermentanomics: Relating quality attributes of a monoclonal antibody to cell culture process variables and raw materials using multivariate data analysis
inferred← citeshttps://doi.org/10.1002/btpr.3330openalex-snapshot
Experimental and computational characterization of mass transfer in high turndown bioreactors
inferred← citeshttps://doi.org/10.1002/btpr.3507openalex-snapshot
CHO stable pool fed‐batch process development of SARS ‐ CoV ‐2 spike protein production: Impact of aeration conditions and feeding strategies
inferred← citeshttps://doi.org/10.1007/978-3-030-79871-0_12openalex-snapshot
Practical Considerations for the Scale-Up of Chinese Hamster Ovary (CHO) Cell Cultures
inferred← citeshttps://doi.org/10.1007/978-81-322-2837-0_7openalex-snapshot
Role of Proteomics in Characterization of Biosimilar Products
inferred← citeshttps://doi.org/10.1016/j.bej.2018.01.031openalex-snapshot
Intracellular response of CHO cells to oxidative stress and its influence on metabolism and antibody production
inferred← citeshttps://doi.org/10.1016/j.bej.2019.02.006openalex-snapshot
CHO cell cultures in shake flasks and bioreactors present different host cell protein profiles in the supernatant
inferred← citeshttps://doi.org/10.1016/j.biortech.2021.125793openalex-snapshot
Membrane bioreactors for the production of value-added products: Recent developments, challenges and perspectives
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2019.02.012openalex-snapshot
Apoptosis: A mammalian cell bioprocessing perspective
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2026.109009openalex-snapshot
Measuring hydrodynamic stress in mammalian cell culture across five decades: Cellular responses and the need for mechanistic integration
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2017.05.040openalex-snapshot
Investigation of interfacial properties of pure and mixed poloxamers for surfactant-mediated shear protection of mammalian cells
inferred← citeshttps://doi.org/10.1016/j.jbiotec.2014.08.026openalex-snapshot
Evaluating the impact of cell culture process parameters on monoclonal antibody N-glycosylation
inferred← citeshttps://doi.org/10.1016/j.jgeb.2025.100638openalex-snapshot
Bioreactors expansion of human mesenchymal stromal cell therapies: platforms, parameters, challenges and opportunities
inferred← citeshttps://doi.org/10.1016/j.jpba.2021.114249openalex-snapshot
Method development for the clearance study of the Pluronic F-68 nonionic surfactant used in the upstream process of monoclonal antibody production
inferred← citeshttps://doi.org/10.1016/j.seppur.2024.126428openalex-snapshot
Effect of backwash as a strategy for biofouling control in the submerged ceramic membrane bioreactor for high-density cultivations: Process optimization and fouling mechanism at pilot scale
inferred← citeshttps://doi.org/10.1021/acs.analchem.6b01639openalex-snapshot
Automated High-Throughput Permethylation for Glycosylation Analysis of Biologics Using MALDI-TOF-MS
inferred← citeshttps://doi.org/10.1186/s13036-024-00475-8openalex-snapshot
Scale-up of CHO cell cultures: from 96-well-microtiter plates to stirred tank reactors across three orders of magnitude
inferred← citeshttps://doi.org/10.1186/s40064-016-3074-8openalex-snapshot
A synthetic biology standard for Chinese Hamster Ovary cell genome monitoring and contaminant detection by polymerase chain reaction
inferred← citeshttps://doi.org/10.1299/jbse.18-00137openalex-snapshot
Combined automated culture system for tubular structure assembly and maturation for vascular tissue engineering
inferred← citeshttps://doi.org/10.1371/journal.pone.0147553openalex-snapshot
Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It
inferred← citeshttps://doi.org/10.3390/bioengineering8050068openalex-snapshot
Single-Use Bioreactors for Human Pluripotent and Adult Stem Cells: Towards Regenerative Medicine Applications
inferred← citeshttps://doi.org/10.3929/ethz-a-010239626openalex-snapshot
Impact of Process Parameters on Cell Growth, Metabolism and Antibody Glycosylation
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