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Oxidized low‐density lipoprotein promotes vascular endothelial cell dysfunction by stimulating miR‐496 expression and inhibiting the Hippo pathway effector YAP

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/1873-3468.12786openalex-snapshot
Macrophage metabolism in atherosclerosis
inferredcites →https://doi.org/10.1016/j.ccell.2017.04.004openalex-snapshot
Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2
inferredcites →https://doi.org/10.1016/j.cell.2006.07.013openalex-snapshot
The Hippo Pathway Regulates the bantam microRNA to Control Cell Proliferation and Apoptosis in Drosophila
inferredcites →https://doi.org/10.1016/j.cmet.2010.09.010openalex-snapshot
Atherogenic Lipids and Lipoproteins Trigger CD36-TLR2-Dependent Apoptosis in Macrophages Undergoing Endoplasmic Reticulum Stress
inferredcites →https://doi.org/10.1016/j.devcel.2017.02.019openalex-snapshot
Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance
inferredcites →https://doi.org/10.1016/j.ijcard.2016.11.195openalex-snapshot
Conditional knockout of TFPI-1 in VSMCs of mice accelerates atherosclerosis by enhancing AMOT/YAP pathway
inferredcites →https://doi.org/10.1038/cdd.2010.149openalex-snapshot
HDLs inhibit endoplasmic reticulum stress and autophagic response induced by oxidized LDLs
inferredcites →https://doi.org/10.1038/ncb2303openalex-snapshot
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
inferredcites →https://doi.org/10.1038/ncb3464openalex-snapshot
A ROR1–HER3–lncRNA signalling axis modulates the Hippo–YAP pathway to regulate bone metastasis
inferredcites →https://doi.org/10.1038/ncb3467openalex-snapshot
Lnc-ing ROR1–HER3 and Hippo signalling in metastasis
inferredcites →https://doi.org/10.1038/ncomms2876openalex-snapshot
MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1
inferredcites →https://doi.org/10.1038/ncomms7943openalex-snapshot
Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2
inferredcites →https://doi.org/10.1038/nrc3715openalex-snapshot
Hippo promotes microRNA processing
inferredcites →https://doi.org/10.1038/s41467-018-03278-wopenalex-snapshot
A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis
inferredcites →https://doi.org/10.1038/s41559-016-0027openalex-snapshot
The evolutionary origin of plant and animal microRNAs
inferredcites →https://doi.org/10.1038/srep23208openalex-snapshot
The Hippo pathway member YAP enhances human neural crest cell fate and migration
inferredcites →https://doi.org/10.1073/pnas.1704030114openalex-snapshot
YAP/TAZ-CDC42 signaling regulates vascular tip cell migration
inferredcites →https://doi.org/10.1074/jbc.c113.529362openalex-snapshot
The Hippo Pathway Effectors TAZ/YAP Regulate Dicer Expression and MicroRNA Biogenesis through Let-7
inferredcites →https://doi.org/10.1074/jbc.m111.329268openalex-snapshot
Yap1 Protein Regulates Vascular Smooth Muscle Cell Phenotypic Switch by Interaction with Myocardin
inferredcites →https://doi.org/10.1101/gad.1820009openalex-snapshot
Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc
inferredcites →https://doi.org/10.1101/gad.1903310openalex-snapshot
The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation
inferredcites →https://doi.org/10.1111/bph.13806openalex-snapshot
The role of Hippo/yes‐associated protein signalling in vascular remodelling associated with cardiovascular disease
inferredcites →https://doi.org/10.1111/j.1742-4658.2012.08589.xopenalex-snapshot
MicroRNA‐199a targets CD44 to suppress the tumorigenicity and multidrug resistance of ovarian cancer‐initiating cells
inferredcites →https://doi.org/10.1126/scitranslmed.3010841openalex-snapshot
A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice
inferredcites →https://doi.org/10.1186/1476-4598-13-97openalex-snapshot
microRNA 31 functions as an endometrial cancer oncogene by suppressing Hippo tumor suppressor pathway
inferredcites →https://doi.org/10.1242/dev.144337openalex-snapshot
MicroRNAs in neural development: from master regulators to fine-tuners
inferredcites →https://doi.org/10.15252/embj.201696150openalex-snapshot
Endothelial cell metabolism in health and disease: impact of hypoxia
inferredcites →https://doi.org/10.3892/etm.2017.4512openalex-snapshot
Induction of reprogramming of human amniotic epithelial cells into iPS cells by overexpression of Yap, Oct4, and Sox2 through the activation of the Hippo-Yap pathway
inferredcites →https://doi.org/10.3892/ijmm.2011.679openalex-snapshot
microRNA-182 inhibits the proliferation and invasion of human lung adenocarcinoma cells through its effect on human cortical actin-associated protein
inferredcites →https://doi.org/10.3892/ijmm.2012.1182openalex-snapshot
Attenuation of exogenous angiotensin II stress-induced damage and apoptosis in human vascular endothelial cells via microRNA-155 expression
inferredcites →https://doi.org/10.5483/bmbrep.2018.51.3.016openalex-snapshot
Hippo-YAP/TAZ signaling in angiogenesis
inferredcites →https://doi.org/10.7554/elife.08488openalex-snapshot
YAP controls retinal stem cell DNA replication timing and genomic stability
inferredcites →https://doi.org/10.7555/jbr.28.20140020openalex-snapshot
An emerging role for Hippo-YAP signaling in cardiovascular development

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4648218openalex-extracted
DNA Methylation of MicroRNA-365-1 Induces Apoptosis by Targeting DAP3 to Induce Apoptosis Production in Hair Follicle Stem Cells
inferred← citeshttps://doi.org/10.1007/978-3-030-53868-2_10openalex-snapshot
Atherosclerosis
inferred← citeshttps://doi.org/10.1016/j.bbalip.2020.158779openalex-snapshot
Salvianolic acid B ameliorates atherosclerosis via inhibiting YAP/TAZ/JNK signaling pathway in endothelial cells and pericytes
inferred← citeshttps://doi.org/10.1016/j.bcp.2021.114466openalex-snapshot
Shear stress inhibits cardiac microvascular endothelial cells apoptosis to protect against myocardial ischemia reperfusion injury via YAP/miR-206/PDCD4 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.biopha.2021.112445openalex-snapshot
Construction of a circRNA-miRNA-mRNA network revealed the potential mechanism of Buyang Huanwu Decoction in the treatment of cerebral ischemia
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.114692openalex-snapshot
Phytochemicals targeting lncRNAs: A novel direction for neuroprotection in neurological disorders
inferred← citeshttps://doi.org/10.1016/j.mbm.2024.100085openalex-snapshot
YAP/TAZ as mechanobiological signaling pathway in cardiovascular physiological regulation and pathogenesis
inferred← citeshttps://doi.org/10.1016/j.phrs.2020.105009openalex-snapshot
Yes-associated protein and transcriptional coactivator with PDZ-binding motif as new targets in cardiovascular diseases
inferred← citeshttps://doi.org/10.1016/j.phymed.2026.158325openalex-snapshot
Que Zui tea extract alleviates atherosclerosis via liver-vasculature-gut axis by modulating lipid metabolism, inflammation, and gut microbiota in ApoE−/− mice
inferred← citeshttps://doi.org/10.1016/j.prostaglandins.2026.107065openalex-snapshot
The dual role of 25-hydroxycholesterol in atherosclerosis: From homeostatic regulation to plaque instability
inferred← citeshttps://doi.org/10.1016/j.repbio.2020.04.006openalex-snapshot
Polycystic ovary syndrome and endothelial dysfunction: A potential role for soluble lectin-like oxidized low density lipoprotein receptor-1
inferred← citeshttps://doi.org/10.1080/10408363.2021.1974334openalex-snapshot
Oxidized LDL-regulated microRNAs for evaluating vascular endothelial function: molecular mechanisms and potential biomarker roles in atherosclerosis
inferred← citeshttps://doi.org/10.1093/rb/rbae004openalex-snapshot
Vascular endothelial cellular mechanics under hyperglycemia and its role in tissue regeneration
inferred← citeshttps://doi.org/10.1186/s12933-024-02374-0openalex-snapshot
Identification of plasma miR-4505, miR-4743-5p and miR-4750-3p as novel diagnostic biomarkers for coronary artery disease in patients with type 2 diabetes mellitus: a case-control study
inferred← citeshttps://doi.org/10.1186/s43556-026-00477-6openalex-snapshot
Neointimal hyperplasia and vascular restenosis: from molecular mechanisms to therapeutic interventions
inferred← citeshttps://doi.org/10.1371/journal.pone.0329321openalex-snapshot
Differential microRNA profiling of the Marshallese population in Arkansas reveals a higher association with chronic diseases
inferred← citeshttps://doi.org/10.2147/dmso.s282009openalex-snapshot
The Association Between Hyperlipidemia and In-Hospital Outcomes in Takotsubo Cardiomyopathy
inferred← citeshttps://doi.org/10.2174/1381612828666220428090540openalex-snapshot
Hippo: A New Hub for Atherosclerotic Disease
inferred← citeshttps://doi.org/10.3389/fcell.2020.00230openalex-snapshot
The Circular RNA circRNA124534 Promotes Osteogenic Differentiation of Human Dental Pulp Stem Cells Through Modulation of the miR-496/β-Catenin Pathway
inferred← citeshttps://doi.org/10.3389/fcvm.2021.704208openalex-snapshot
Yes-Associated Protein in Atherosclerosis and Related Complications: A Potential Therapeutic Target That Requires Further Exploration
inferred← citeshttps://doi.org/10.3389/fphar.2024.1348280openalex-snapshot
Non-coding RNAs as regulators of the Hippo pathway in cardiac development and cardiovascular disease
inferred← citeshttps://doi.org/10.3390/biomedicines10010147openalex-snapshot
Distinctive Roles of YAP and TAZ in Human Endothelial Progenitor Cells Growth and Functions
inferred← citeshttps://doi.org/10.3390/ijms24021666openalex-snapshot
Yes-Associated Protein and Transcriptional Coactivator with PDZ-Binding Motif in Cardiovascular Diseases
inferred← citeshttps://doi.org/10.3390/ijms24032600openalex-snapshot
The Potential Role of Connexins in the Pathogenesis of Atherosclerosis
inferred← citeshttps://doi.org/10.3390/ijms25158042openalex-snapshot
Molecular Morbidity Score–Can MicroRNAs Assess the Burden of Disease?
inferred← citeshttps://doi.org/10.3892/etm.2019.8259openalex-snapshot
Angiotensin type 1 receptor regulates yes‑associated protein in vascular endothelial cells
inferred← citeshttps://doi.org/10.3892/etm.2019.8356openalex-snapshot
MicroRNA‑496 suppresses tumor cell proliferation by targeting BDNF in osteosarcoma
inferred← citeshttps://doi.org/10.6084/m9.figshare.26755663openalex-snapshot
Additional file 1 of Identification of plasma miR-4505, miR-4743-5p and miR-4750-3p as novel diagnostic biomarkers for coronary artery disease in patients with type 2 diabetes mellitus: a case-control study
inferred← citeshttps://doi.org/10.62347/yzgc6734openalex-snapshot
Decreased expression of LncRNA CRYM-AS1 promotes apoptosis through the Hippo-YAP1 signaling pathway leading to diabetic erectile dysfunction
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