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Evolution of aberrant brain‐wide spatiotemporal dynamics of resting‐state networks in a Huntington's disease mouse model

https://doi.org/10.1002/ctm2.70055
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Cerebrovascular and blood–brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology
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Aberrant astrocytes impair vascular reactivity in H untington disease
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Overview of Huntington's Disease Models: Neuropathological, Molecular, and Behavioral Differences
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High content image cytometry in the context of subnuclear organization
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Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell‐type‐specific
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Spontaneous low‐frequency BOLD signal fluctuations: An fMRI investigation of the resting‐state default mode of brain function hypothesis
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Aberrant brain network connectivity in presymptomatic and manifest Huntington's disease: A systematic review
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Spatiotemporal dynamics of low frequency fluctuations in BOLD fMRI of the rat
inferredcites →https://doi.org/10.1002/jnr.24503openalex-snapshot
Developmental origins of cortical hyperexcitability in Huntington's disease: Review and new observations
inferredcites →https://doi.org/10.1002/mds.28839openalex-snapshot
Structure and Dynamics of Large‐Scale Cognitive Networks in Huntington's Disease
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Correlations in Low-Frequency BOLD Fluctuations Reflect Cortico-Cortical Connections
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Cell Detection with Star-Convex Polygons
inferredcites →https://doi.org/10.1007/978-3-319-71779-1_1openalex-snapshot
Clinical Features of Huntington’s Disease
inferredcites →https://doi.org/10.1016/0092-8674(93)90585-eopenalex-snapshot
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
inferredcites →https://doi.org/10.1016/b978-0-12-801893-4.00020-1openalex-snapshot
Structural imaging in premanifest and manifest Huntington disease
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Neurobiology and consequences of social isolation stress in animal model—A comprehensive review
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Systematic Quantification of Synapses in Primary Neuronal Culture
inferredcites →https://doi.org/10.1016/j.nbd.2009.05.007openalex-snapshot
Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models
inferredcites →https://doi.org/10.1016/j.nbd.2023.106095openalex-snapshot
Resting-state fMRI reveals longitudinal alterations in brain network connectivity in the zQ175DN mouse model of Huntington's disease
inferredcites →https://doi.org/10.1016/j.nbd.2024.106438openalex-snapshot
Diffusion MRI marks progressive alterations in fiber integrity in the zQ175DN mouse model of Huntington's disease
inferredcites →https://doi.org/10.1016/j.neubiorev.2013.01.022openalex-snapshot
Structural MRI in Huntington's disease and recommendations for its potential use in clinical trials
inferredcites →https://doi.org/10.1016/j.neurobiolaging.2008.12.007openalex-snapshot
VEGF protects motor neurons against excitotoxicity by upregulation of GluR2
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Reduced functional connectivity in early-stage drug-naive Parkinson's disease: a resting-state fMRI study
inferredcites →https://doi.org/10.1016/j.neuroimage.2010.08.030openalex-snapshot
Spatiotemporal dynamics of low frequency BOLD fluctuations in rats and humans
inferredcites →https://doi.org/10.1016/j.neuroimage.2015.04.033openalex-snapshot
Functional connectivity hubs of the mouse brain
inferredcites →https://doi.org/10.1016/j.neuroimage.2018.01.075openalex-snapshot
Dynamic resting state fMRI analysis in mice reveals a set of Quasi-Periodic Patterns and illustrates their relationship with the global signal
inferredcites →https://doi.org/10.1016/j.neuroimage.2019.01.076openalex-snapshot
Quasi-periodic patterns contribute to functional connectivity in the brain
inferredcites →https://doi.org/10.1016/j.neuroimage.2020.117528openalex-snapshot
Gradients of functional connectivity in the mouse cortex reflect neocortical evolution
inferredcites →https://doi.org/10.1016/j.neuroimage.2021.117827openalex-snapshot
Propagating patterns of intrinsic activity along macroscale gradients coordinate functional connections across the whole brain
inferredcites →https://doi.org/10.1016/j.neuron.2014.10.015openalex-snapshot
The Chronnectome: Time-Varying Connectivity Networks as the Next Frontier in fMRI Data Discovery
inferredcites →https://doi.org/10.1016/j.neuron.2020.11.011openalex-snapshot
Regional, Layer, and Cell-Type-Specific Connectivity of the Mouse Default Mode Network
inferredcites →https://doi.org/10.1016/j.nicl.2013.03.001openalex-snapshot
Reduced functional brain connectivity prior to and after disease onset in Huntington's disease
inferredcites →https://doi.org/10.1016/j.nicl.2019.101653openalex-snapshot
Quasi-periodic patterns of brain activity in individuals with attention-deficit/hyperactivity disorder
inferredcites →https://doi.org/10.1016/j.nicl.2019.101913openalex-snapshot
Cortical neurodevelopment in pre-manifest Huntington's disease
inferredcites →https://doi.org/10.1016/j.tins.2017.05.002openalex-snapshot
Unravelling and Exploiting Astrocyte Dysfunction in Huntington’s Disease
inferredcites →https://doi.org/10.1016/j.ymeth.2015.01.005openalex-snapshot
Robust methods to create ex vivo minimum deformation atlases for brain mapping
inferredcites →https://doi.org/10.1016/s0006-8993(00)02825-0openalex-snapshot
Expression of vascular endothelial growth factor by reactive astrocytes and associated neoangiogenesis
inferredcites →https://doi.org/10.1016/s0166-2236(00)01705-7openalex-snapshot
Mechanisms underlying neural cell death in neurodegenerative diseases: alterations of a developmentally-mediated cellular rheostat
inferredcites →https://doi.org/10.1016/s1361-8415(98)80009-1openalex-snapshot
Three-dimensional multi-scale line filter for segmentation and visualization of curvilinear structures in medical images
inferredcites →https://doi.org/10.1038/mt.2013.132openalex-snapshot
Dose-dependent Neuroprotection of VEGF165 in Huntington's Disease Striatum
inferredcites →https://doi.org/10.1038/nature13165openalex-snapshot
Capillary pericytes regulate cerebral blood flow in health and disease
inferredcites →https://doi.org/10.1038/nmeth.2019openalex-snapshot
Fiji: an open-source platform for biological-image analysis
inferredcites →https://doi.org/10.1038/nn.3691openalex-snapshot
Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice
inferredcites →https://doi.org/10.1038/nn.4332openalex-snapshot
The mouse cortico-striatal projectome
inferredcites →https://doi.org/10.1038/nrdp.2015.5openalex-snapshot
Huntington disease
inferredcites →https://doi.org/10.1038/nrneurol.2014.24openalex-snapshot
Huntington disease: natural history, biomarkers and prospects for therapeutics
inferredcites →https://doi.org/10.1038/nrneurol.2016.88openalex-snapshot
Vascular endothelial growth factor: a neurovascular target in neurological diseases
inferredcites →https://doi.org/10.1038/s41586-021-03993-3openalex-snapshot
The mouse cortico–basal ganglia–thalamic network
inferredcites →https://doi.org/10.1038/s41598-018-28237-9openalex-snapshot
Quasi-Periodic Patterns of Neural Activity improve Classification of Alzheimer’s Disease in Mice
inferredcites →https://doi.org/10.1038/s41598-023-36812-yopenalex-snapshot
Longitudinal investigation of changes in resting-state co-activation patterns and their predictive ability in the zQ175 DN mouse model of Huntington’s disease
inferredcites →https://doi.org/10.1038/s42003-020-01622-9openalex-snapshot
Organisational and neuromodulatory underpinnings of structural-functional connectivity decoupling in patients with Parkinson’s disease
inferredcites →https://doi.org/10.1073/pnas.0135058100openalex-snapshot
Functional connectivity in the resting brain: A network analysis of the default mode hypothesis
inferredcites →https://doi.org/10.1073/pnas.1608282113openalex-snapshot
Situating the default-mode network along a principal gradient of macroscale cortical organization
inferredcites →https://doi.org/10.1073/pnas.1814144116openalex-snapshot
Multimodal gradients across mouse cortex
inferredcites →https://doi.org/10.1073/pnas.1903403116openalex-snapshot
Gradients of structure–function tethering across neocortex
inferredcites →https://doi.org/10.1073/pnas.2202435120openalex-snapshot
Hemodynamic transient and functional connectivity follow structural connectivity and cell type over the brain hierarchy
inferredcites →https://doi.org/10.1089/brain.2012.0115openalex-snapshot
Dynamic Properties of Functional Connectivity in the Rodent
inferredcites →https://doi.org/10.1093/brain/awab190openalex-snapshot
Huntingtin silencing delays onset and slows progression of Huntington’s disease: a biomarker study
inferredcites →https://doi.org/10.1093/braincomms/fcad010openalex-snapshot
Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches
inferredcites →https://doi.org/10.1093/cercor/bhs352openalex-snapshot
Tracking Whole-Brain Connectivity Dynamics in the Resting State
inferredcites →https://doi.org/10.1093/cercor/bhz245openalex-snapshot
Cortical Network Dynamics Is Altered in Mouse Models of Huntington’s Disease
inferredcites →https://doi.org/10.1093/hmg/ddad191openalex-snapshot
Age- and region-dependent cortical excitability in the zQ175 Huntington disease mouse model
inferredcites →https://doi.org/10.1093/hmg/ddw212openalex-snapshot
An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes
inferredcites →https://doi.org/10.1093/texcom/tgaa044openalex-snapshot
Abnormal Brain Development in Huntington’ Disease Is Recapitulated in the zQ175 Knock-In Mouse Model
inferredcites →https://doi.org/10.1111/ejn.12575openalex-snapshot
Visual system integrity and cognition in early Huntington's disease
inferredcites →https://doi.org/10.1111/nyas.14977openalex-snapshot
Astrocytic contributions to Huntington's disease pathophysiology
inferredcites →https://doi.org/10.1126/science.aax3338openalex-snapshot
Huntington’s disease alters human neurodevelopment
inferredcites →https://doi.org/10.1126/science.abq5011openalex-snapshot
Treating early postnatal circuit defect delays Huntington’s disease onset and pathology in mice
inferredcites →https://doi.org/10.1126/scitranslmed.aaw8546openalex-snapshot
Astrocyte molecular signatures in Huntington’s disease
inferredcites →https://doi.org/10.1142/9781860947162_0015openalex-snapshot
THE MOUSE IN BIOMEDICAL RESEARCH
inferredcites →https://doi.org/10.1148/radiol.10091701openalex-snapshot
Resting Brain Connectivity: Changes during the Progress of Alzheimer Disease
inferredcites →https://doi.org/10.1152/jn.00235.2015openalex-snapshot
Different dynamic resting state fMRI patterns are linked to different frequencies of neural activity
inferredcites →https://doi.org/10.1152/jn.01056.2014openalex-snapshot
Altered excitatory and inhibitory inputs to striatal medium-sized spiny neurons and cortical pyramidal neurons in the Q175 mouse model of Huntington's disease
inferredcites →https://doi.org/10.1152/physrev.00031.2008openalex-snapshot
Role and Therapeutic Potential of VEGF in the Nervous System
inferredcites →https://doi.org/10.1172/jci200420682openalex-snapshot
VEGF: a critical player in neurodegeneration
inferredcites →https://doi.org/10.1172/jci20682openalex-snapshot
VEGF: a critical player in neurodegeneration
inferredcites →https://doi.org/10.1177/1073858420972662openalex-snapshot
Synaptic Dysfunction in Huntington’s Disease: Lessons from Genetic Animal Models
inferredcites →https://doi.org/10.1186/2045-8118-8-8openalex-snapshot
The CNS microvascular pericyte: pericyte-astrocyte crosstalk in the regulation of tissue survival
inferredcites →https://doi.org/10.1186/s12929-024-01028-3openalex-snapshot
Longitudinal alterations in brain perfusion and vascular reactivity in the zQ175DN mouse model of Huntington’s disease
inferredcites →https://doi.org/10.1186/s13195-017-0329-8openalex-snapshot
Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology
inferredcites →https://doi.org/10.1186/s13195-022-01089-2openalex-snapshot
Altered basal forebrain function during whole-brain network activity at pre- and early-plaque stages of Alzheimer’s disease in TgF344-AD rats
inferredcites →https://doi.org/10.1186/s40478-019-0741-3openalex-snapshot
High-throughput microscopy exposes a pharmacological window in which dual leucine zipper kinase inhibition preserves neuronal network connectivity
inferredcites →https://doi.org/10.1212/wnl.0000000000008066openalex-snapshot
Abnormal brain development in child and adolescent carriers of mutant huntingtin
inferredcites →https://doi.org/10.1212/wnl.0000000000009364openalex-snapshot
Abnormal development of cerebellar-striatal circuitry in Huntington disease
inferredcites →https://doi.org/10.1371/journal.pbio.3001735openalex-snapshot
Human electromagnetic and haemodynamic networks systematically converge in unimodal cortex and diverge in transmodal cortex
inferredcites →https://doi.org/10.1371/journal.pone.0049838openalex-snapshot
Comprehensive Behavioral and Molecular Characterization of a New Knock-In Mouse Model of Huntington’s Disease: zQ175
inferredcites →https://doi.org/10.1371/journal.pone.0050717openalex-snapshot
Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease
inferredcites →https://doi.org/10.1371/journal.pone.0123527openalex-snapshot
Characterization of HTT Inclusion Size, Location, and Timing in the zQ175 Mouse Model of Huntington´s Disease: An In Vivo High-Content Imaging Study
inferredcites →https://doi.org/10.1371/journal.pone.0243052openalex-snapshot
Rapid and robust patterns of spontaneous locomotor deficits in mouse models of Huntington’s disease
inferredcites →https://doi.org/10.1387/ijdb.103167dropenalex-snapshot
The role of pericytes in angiogenesis
inferredcites →https://doi.org/10.1503/jpn.120226openalex-snapshot
Abnormal synchrony of resting state networks in premanifest and symptomatic Huntington disease: the IMAGE-HD study
inferredcites →https://doi.org/10.1523/eneuro.0452-22.2022openalex-snapshot
Water-Reaching Platform for Longitudinal Assessment of Cortical Activity and Fine Motor Coordination Defects in a Huntington Disease Mouse Model
inferredcites →https://doi.org/10.1523/jneurosci.2180-11.2011openalex-snapshot
Mapping Human Cortical Areas In Vivo Based on Myelin Content as Revealed by T1- and T2-Weighted MRI
inferredcites →https://doi.org/10.3233/jhd-200394openalex-snapshot
The Neurodevelopmental Hypothesis of Huntington’s Disease
inferredcites →https://doi.org/10.3389/fncel.2019.00282openalex-snapshot
Pericytes and Neurovascular Function in the Healthy and Diseased Brain
inferredcites →https://doi.org/10.3389/fncir.2017.00005openalex-snapshot
Resting State fMRI in Mice Reveals Anesthesia Specific Signatures of Brain Functional Networks and Their Interactions
inferredcites →https://doi.org/10.3389/fnint.2014.00041openalex-snapshot
Phase-amplitude coupling and infraslow (<1 Hz) frequencies in the rat brain: relationship to resting state fMRI

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← backgroundhttps://doi.org/10.5281/zenodo.17358892zenodo-depositor-declared
inferred← citeshttps://doi.org/10.1002/brb3.71058openalex-snapshot
Neurovascular Coupling: Scientometric Analysis of 30 Years Research (1996–2025)
inferred← citeshttps://doi.org/10.1016/j.expneurol.2025.115461openalex-snapshot
Progressively reduced cerebral oxygen metabolism and elevated plasma NfL levels in the zQ175DN mouse model of Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.nbd.2025.107154openalex-snapshot
Longitudinal investigation of structural and resting-state effective connectivity alterations in a non-human primate model of Huntington's disease
inferred← citeshttps://doi.org/10.1038/s41596-025-01250-9openalex-snapshot
Measurement of electrochemical brain activity with fast-scan cyclic voltammetry during functional magnetic resonance imaging
inferred← citeshttps://doi.org/10.1186/s12929-024-01028-3openalex-snapshot
Longitudinal alterations in brain perfusion and vascular reactivity in the zQ175DN mouse model of Huntington’s disease
inferred← citeshttps://doi.org/10.1186/s40364-026-00971-7openalex-snapshot
Mapping brain volume changes in the zQ175DN mouse model of Huntington’s disease: a longitudinal MRI study
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