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Hepatic fibrosis 2022: Unmet needs and a blueprint for the future
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Liver sinusoidal endothelial cells in hepatic fibrosis
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The PNPLA3 I148M variant modulates the fibrogenic phenotype of human hepatic stellate cells
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The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation
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Current and future therapeutic regimens for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
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A Bioreactor Technology for Modeling Fibrosis in Human and Rodent Precision‐Cut Liver Slices
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Defining Improvement in Nonalcoholic Steatohepatitis for Treatment Trial Endpoints: Recommendations From the Liver Forum
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Noninvasive Tests Accurately Identify Advanced Fibrosis due to NASH: Baseline Data From the STELLAR Trials
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Application of Artificial Intelligence for the Diagnosis and Treatment of Liver Diseases
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Heterogeneity of HSCs in a Mouse Model of NASH
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A Machine Learning Approach Enables Quantitative Measurement of Liver Histology and Disease Monitoring in NASH
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Ten Thousand Points of Light: Heterogeneity Among the Stars of NASH Fibrosis
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A Machine Learning Approach to Liver Histological Evaluation Predicts Clinically Significant Portal Hypertension in NASH Cirrhosis
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Cirrhosis regression is associated with improved clinical outcomes in patients with nonalcoholic steatohepatitis
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An Algorithm for the Grading of Activity in Chronic Hepatitis C
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Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: Role of nitric oxide
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Metabolomic‐based noninvasive serum test to diagnose nonalcoholic steatohepatitis: Results from discovery and validation cohorts
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Clinical value of serum hyaluronan and propeptide of type III collagen in patients with pancreatic cancer
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The biphasic nature of hypoxia‐induced directional migration of activated human hepatic stellate cells
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Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury
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Collagen-targeted molecular imaging in diffuse liver diseases
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Portal myofibroblasts connect angiogenesis and fibrosis in liver
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The gut mycobiome: a novel player in chronic liver diseases
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Machine Learning in Drug Discovery: A Review
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Applying Non-Invasive Fibrosis Measurements in NAFLD/NASH: Progress to Date
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Histological grading and staging of chronic hepatitis
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Hepatic stellate cells as key target in liver fibrosis
inferredcites →https://doi.org/10.1016/j.antiviral.2014.03.012openalex-snapshot
Reversal, maintenance or progression: What happens to the liver after a virologic cure of hepatitis C?
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Management of Idiopathic Pulmonary Fibrosis
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Microscopic examination of spatial transcriptome using Seq-Scope
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Organs-on-a-chip models for biological research
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Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis
inferredcites →https://doi.org/10.1016/j.cgh.2021.04.030openalex-snapshot
HepQuant SHUNT Detects Portal Hypertension in Early Stages of Clinically Compensated Chronic Liver Disease
inferredcites →https://doi.org/10.1016/j.cld.2017.08.003openalex-snapshot
The Natural History of Nonalcoholic Fatty Liver Disease—An Evolving View
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Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids
inferredcites →https://doi.org/10.1016/j.cmet.2020.06.005openalex-snapshot
A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis
inferredcites →https://doi.org/10.1016/j.cmet.2021.06.005openalex-snapshot
Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication
inferredcites →https://doi.org/10.1016/j.crad.2019.11.001openalex-snapshot
Gadoxetate-disodium-enhanced magnetic resonance imaging for liver fibrosis staging: a systematic review and meta-analysis
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A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie–Wnt signaling axis in the liver
inferredcites →https://doi.org/10.1016/j.dld.2004.01.003openalex-snapshot
Liver fibrosis: from the bench to clinical targets
inferredcites →https://doi.org/10.1016/j.jcmgh.2017.04.007openalex-snapshot
Epigenetics and Liver Fibrosis
inferredcites →https://doi.org/10.1016/j.jcmgh.2020.12.007openalex-snapshot
Single-Cell Transcriptomics Reveals Zone-Specific Alterations of Liver Sinusoidal Endothelial Cells in Cirrhosis
inferredcites →https://doi.org/10.1016/j.jhep.2013.12.023openalex-snapshot
Collagen proportionate area is superior to other histological methods for sub-classifying cirrhosis and determining prognosis
inferredcites →https://doi.org/10.1016/j.jhep.2017.10.015openalex-snapshot
Pharmacotherapy for NASH: Current and emerging
inferredcites →https://doi.org/10.1016/j.jhep.2017.11.014openalex-snapshot
Lipotoxicity and the gut-liver axis in NASH pathogenesis
inferredcites →https://doi.org/10.1016/j.jhep.2020.03.036openalex-snapshot
Enhanced liver fibrosis test for the non-invasive diagnosis of fibrosis in patients with NAFLD: A systematic review and meta-analysis
inferredcites →https://doi.org/10.1016/j.jhep.2020.04.034openalex-snapshot
STELLAR 3 and STELLAR 4: Lessons from the fall of Icarus
inferredcites →https://doi.org/10.1016/j.jhep.2020.06.004openalex-snapshot
Single-cell genomics and spatial transcriptomics: Discovery of novel cell states and cellular interactions in liver physiology and disease biology
inferredcites →https://doi.org/10.1016/j.jhep.2020.10.003openalex-snapshot
Agreement between wedged hepatic venous pressure and portal pressure in non-alcoholic steatohepatitis-related cirrhosis
inferredcites →https://doi.org/10.1016/j.matbio.2017.11.011openalex-snapshot
Matrix metalloproteinase functions in hepatic injury and fibrosis
inferredcites →https://doi.org/10.1016/j.molcel.2019.07.028openalex-snapshot
Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis
inferredcites →https://doi.org/10.1016/j.molmed.2015.07.006openalex-snapshot
Modeling Disease In Vivo With CRISPR/Cas9
inferredcites →https://doi.org/10.1016/j.molmet.2021.101167openalex-snapshot
Imaging biomarkers of NAFLD, NASH, and fibrosis
inferredcites →https://doi.org/10.1016/j.stem.2020.04.003openalex-snapshot
Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids
inferredcites →https://doi.org/10.1016/j.tips.2018.01.003openalex-snapshot
Specialized Proresolving Mediators: Enhancing Nonalcoholic Steatohepatitis and Fibrosis Resolution
inferredcites →https://doi.org/10.1016/s0140-6736(12)61425-1openalex-snapshot
Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study
inferredcites →https://doi.org/10.1016/s0270-9139(02)00091-5openalex-snapshot
Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse
inferredcites →https://doi.org/10.1016/s2468-1253(20)30252-1openalex-snapshot
A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study
inferredcites →https://doi.org/10.1021/acs.chemrev.7b00120openalex-snapshot
Proteolytic Cleavage—Mechanisms, Function, and “Omic” Approaches for a Near-Ubiquitous Posttranslational Modification
inferredcites →https://doi.org/10.1038/aps.2016.134openalex-snapshot
Lowering serum lipids via PCSK9-targeting drugs: current advances and future perspectives
inferredcites →https://doi.org/10.1038/cmi.2015.104openalex-snapshot
Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies
inferredcites →https://doi.org/10.1038/emboj.2011.139openalex-snapshot
AT1R–CB1R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II
inferredcites →https://doi.org/10.1038/nbt1396openalex-snapshot
Resolution of liver cirrhosis using vitamin A–coupled liposomes to deliver siRNA against a collagen-specific chaperone
inferredcites →https://doi.org/10.1038/nm.3679openalex-snapshot
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer
inferredcites →https://doi.org/10.1038/nm0511-552openalex-snapshot
Scraping fibrosis: Expressway to the core of fibrosis
inferredcites →https://doi.org/10.1038/nn.4620openalex-snapshot
AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma
inferredcites →https://doi.org/10.1038/nrgastro.2017.38openalex-snapshot
Mechanisms of hepatic stellate cell activation
inferredcites →https://doi.org/10.1038/nri.2017.11openalex-snapshot
Liver macrophages in tissue homeostasis and disease
inferredcites →https://doi.org/10.1038/nri3623openalex-snapshot
Liver fibrosis and repair: immune regulation of wound healing in a solid organ
inferredcites →https://doi.org/10.1038/s41467-018-06318-7openalex-snapshot
Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations
inferredcites →https://doi.org/10.1038/s41467-019-09455-9openalex-snapshot
A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease
inferredcites →https://doi.org/10.1038/s41467-020-15647-5openalex-snapshot
Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis
inferredcites →https://doi.org/10.1038/s41575-020-0304-xopenalex-snapshot
Single-cell technologies in hepatology: new insights into liver biology and disease pathogenesis
inferredcites →https://doi.org/10.1038/s41586-019-1373-2openalex-snapshot
A human liver cell atlas reveals heterogeneity and epithelial progenitors
inferredcites →https://doi.org/10.1038/s41586-019-1631-3openalex-snapshot
Resolving the fibrotic niche of human liver cirrhosis at single-cell level
inferredcites →https://doi.org/10.1038/s41586-020-2941-1openalex-snapshot
Decoding myofibroblast origins in human kidney fibrosis
inferredcites →https://doi.org/10.1038/s41586-021-03362-0openalex-snapshot
NASH limits anti-tumour surveillance in immunotherapy-treated HCC
inferredcites →https://doi.org/10.1038/s41586-021-03549-5openalex-snapshot
Cross-tissue organization of the fibroblast lineage
inferredcites →https://doi.org/10.1038/s41591-018-0104-9openalex-snapshot
Mechanisms of NAFLD development and therapeutic strategies
inferredcites →https://doi.org/10.1038/s41596-021-00509-1openalex-snapshot
Directed differentiation of human induced pluripotent stem cells to hepatic stellate cells
inferredcites →https://doi.org/10.1038/s41598-017-05134-1openalex-snapshot
Rapid production of human liver scaffolds for functional tissue engineering by high shear stress oscillation-decellularization
inferredcites →https://doi.org/10.1038/s41598-021-99008-2openalex-snapshot
Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis
inferredcites →https://doi.org/10.1038/srep15408openalex-snapshot
Liver fibrosis and Gd-EOB-DTPA-enhanced MRI: A histopathologic correlation
inferredcites →https://doi.org/10.1038/srep27414openalex-snapshot
Endophenotype Network Models: Common Core of Complex Diseases
inferredcites →https://doi.org/10.1038/srep42563openalex-snapshot
Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells
inferredcites →https://doi.org/10.1039/c6ib00027dopenalex-snapshot
Gradually softening hydrogels for modeling hepatic stellate cell behavior during fibrosis regression
inferredcites →https://doi.org/10.1053/j.gastro.2003.12.045openalex-snapshot
Treatment with human metalloproteinase-8 gene delivery ameliorates experimental rat liver cirrhosis
inferredcites →https://doi.org/10.1053/j.gastro.2011.12.017openalex-snapshot
Role of Differentiation of Liver Sinusoidal Endothelial Cells in Progression and Regression of Hepatic Fibrosis in Rats
inferredcites →https://doi.org/10.1053/j.gastro.2014.01.061openalex-snapshot
Vascular Endothelial Growth Factor Promotes Fibrosis Resolution and Repair in Mice
inferredcites →https://doi.org/10.1053/j.gastro.2016.09.065openalex-snapshot
Using Big Data to Discover Diagnostics and Therapeutics for Gastrointestinal and Liver Diseases
inferredcites →https://doi.org/10.1053/j.gastro.2017.01.015openalex-snapshot
Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis
inferredcites →https://doi.org/10.1053/j.gastro.2018.06.031openalex-snapshot
Bioactive Lipid Species and Metabolic Pathways in Progression and Resolution of Nonalcoholic Steatohepatitis
inferredcites →https://doi.org/10.1053/j.gastro.2020.06.006openalex-snapshot
Bariatric Surgery Provides Long-term Resolution of Nonalcoholic Steatohepatitis and Regression of Fibrosis
inferredcites →https://doi.org/10.1053/j.gastro.2020.07.005openalex-snapshot
Intestinal Virome Signature Associated With Severity of Nonalcoholic Fatty Liver Disease
inferredcites →https://doi.org/10.1053/j.gastro.2020.09.065openalex-snapshot
Fibrosis Regression After Eradication of Hepatitis C Virus: From Bench to Bedside
inferredcites →https://doi.org/10.1055/s-2001-17555openalex-snapshot
Interactions between Hepatic Stellate Cells and the Immune System
inferredcites →https://doi.org/10.1073/pnas.1119964109openalex-snapshot
Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis
inferredcites →https://doi.org/10.1073/pnas.82.24.8681openalex-snapshot
Hepatic lipocytes: the principal collagen-producing cells of normal rat liver.
inferredcites →https://doi.org/10.1074/jbc.275.17.12743openalex-snapshot
Successful Targeting to Rat Hepatic Stellate Cells Using Albumin Modified with Cyclic Peptides That Recognize the Collagen Type VI Receptor
inferredcites →https://doi.org/10.1080/14656566.2020.1744564openalex-snapshot
Current and new pharmacotherapy options for non-alcoholic steatohepatitis
inferredcites →https://doi.org/10.1093/toxsci/kfi127openalex-snapshot
Precision-Cut Liver Slices as a New Model to Study Toxicity-Induced Hepatic Stellate Cell Activation in a Physiologic Milieu
inferredcites →https://doi.org/10.1097/01.lab.0000069036.63405.5copenalex-snapshot
Apoptotic Body Engulfment by a Human Stellate Cell Line Is Profibrogenic
inferredcites →https://doi.org/10.1111/apt.15773openalex-snapshot
Review article: the signalling and functional role of the extracellular matrix in the development of liver fibrosis
inferredcites →https://doi.org/10.1111/apt.16100openalex-snapshot
Digital pathology: accurate technique for quantitative assessment of histological features in metabolic‐associated fatty liver disease
inferredcites →https://doi.org/10.1111/apt.16283openalex-snapshot
Predicting clinical decompensation in patients with cirrhosis using the Hepquant‐SHUNT test
inferredcites →https://doi.org/10.1111/j.1365-2559.2011.04094.xopenalex-snapshot
Fibrosis distribution in explanted cirrhotic livers
inferredcites →https://doi.org/10.1111/liv.13268openalex-snapshot
Potential use of metabolic breath tests to assess liver disease and prognosis: has the time arrived for routine use in the clinic?
inferredcites →https://doi.org/10.1111/liv.14118openalex-snapshot
Accuracy of imaging methods for steatohepatitis diagnosis in non‐alcoholic fatty liver disease patients: A systematic review
inferredcites →https://doi.org/10.1111/liv.14452openalex-snapshot
Cell‐type‐resolved proteomic analysis of the human liver
inferredcites →https://doi.org/10.1126/scitranslmed.3002648openalex-snapshot
Computational Repositioning of the Anticonvulsant Topiramate for Inflammatory Bowel Disease
inferredcites →https://doi.org/10.1126/scitranslmed.3005975openalex-snapshot
Cell and tissue engineering for liver disease
inferredcites →https://doi.org/10.1126/scitranslmed.aaa9364openalex-snapshot
Identification of type 2 diabetes subgroups through topological analysis of patient similarity
inferredcites →https://doi.org/10.1126/scitranslmed.aan8462openalex-snapshot
Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia
inferredcites →https://doi.org/10.1126/scitranslmed.aba4448openalex-snapshot
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis
inferredcites →https://doi.org/10.1126/scitranslmed.abe8939openalex-snapshot
Peptide-based urinary monitoring of fibrotic nonalcoholic steatohepatitis by mass-barcoded activity-based sensors
inferredcites →https://doi.org/10.1136/gutjnl-2014-306996openalex-snapshot
Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis
inferredcites →https://doi.org/10.1136/gutjnl-2018-317593openalex-snapshot
Advances in non-invasive assessment of hepatic fibrosis
inferredcites →https://doi.org/10.1136/gutjnl-2020-322880openalex-snapshot
Artificial intelligence-based pathology for gastrointestinal and hepatobiliary cancers
inferredcites →https://doi.org/10.1136/gutjnl-2021-324243openalex-snapshot
Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis
inferredcites →https://doi.org/10.1172/jci1018openalex-snapshot
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors.
inferredcites →https://doi.org/10.1172/jci115850openalex-snapshot
Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1. Implications for regulation of matrix degradation in liver.
inferredcites →https://doi.org/10.1172/jci117497openalex-snapshot
Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture.
inferredcites →https://doi.org/10.1172/jci200522675openalex-snapshot
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
inferredcites →https://doi.org/10.1177/1535370215584933openalex-snapshot
Bone marrow-derived fibrocytes contribute to liver fibrosis
inferredcites →https://doi.org/10.1177/1536012119871455openalex-snapshot
PET/SPECT Molecular Probes for the Diagnosis and Staging of Nonalcoholic Fatty Liver Disease
inferredcites →https://doi.org/10.1177/2472555220915851openalex-snapshot
A Whole Genome-Wide Arrayed CRISPR Screen in Primary Organ Fibroblasts to Identify Regulators of Kidney Fibrosis
inferredcites →https://doi.org/10.1186/s12876-020-01585-5openalex-snapshot
Application of artificial intelligence in chronic liver diseases: a systematic review and meta-analysis
inferredcites →https://doi.org/10.1186/s13550-015-0151-xopenalex-snapshot
Targeting activated hepatic stellate cells (aHSCs) for liver fibrosis imaging
inferredcites →https://doi.org/10.14309/ctg.0000000000000239openalex-snapshot
Breath Biopsy Assessment of Liver Disease Using an Exogenous Volatile Organic Compound—Toward Improved Detection of Liver Impairment
inferredcites →https://doi.org/10.1586/egh.10.47openalex-snapshot
Update on the pathophysiology of liver fibrosis
inferredcites →https://doi.org/10.2174/1568026615666150112103510openalex-snapshot
Computational and Experimental Advances in Drug Repositioning for Accelerated Therapeutic Stratification
inferredcites →https://doi.org/10.3389/fcell.2021.652408openalex-snapshot
Integrating Spatial Transcriptomics and Single-Cell RNA-seq Reveals the Gene Expression Profling of the Human Embryonic Liver
inferredcites →https://doi.org/10.3390/biomedicines9040378openalex-snapshot
Modeling Diet-Induced NAFLD and NASH in Rats: A Comprehensive Review
inferredcites →https://doi.org/10.3390/cells10071805openalex-snapshot
Diet-Induced Models of Non-Alcoholic Fatty Liver Disease: Food for Thought on Sugar, Fat, and Cholesterol
inferredcites →https://doi.org/10.3390/cells9010083openalex-snapshot
Cirrhotic Human Liver Extracellular Matrix 3D Scaffolds Promote Smad-Dependent TGF-β1 Epithelial Mesenchymal Transition
inferredcites →https://doi.org/10.3390/cells9051212openalex-snapshot
Matrix Metalloproteinases as Potential Biomarkers and Therapeutic Targets in Liver Diseases
inferredcites →https://doi.org/10.3390/jcm10071338openalex-snapshot
Role of Angiogenesis in the Pathogenesis of NAFLD
inferredcites →https://doi.org/10.3390/molecules24224188openalex-snapshot
The Versatile Role of Matrix Metalloproteinase for the Diverse Results of Fibrosis Treatment
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4639835openalex-extracted
Wuling Capsule Modulates Macrophage Polarization by Inhibiting the TLR4-NF-κB Signaling Pathway to Relieve Liver Fibrosis
inferred← citeshttps://doi.org/10.1002/adhm.202301485openalex-snapshot
Carbon Nitride‐Based siRNA Vectors with Self‐Produced O2 Effects for Targeting Combination Therapy of Liver Fibrosis via HIF‐1α‐Mediated TGF‐β1/Smad Pathway
inferred← citeshttps://doi.org/10.1002/adma.202307673openalex-snapshot
The Material World of 3D‐Bioprinted and Microfluidic‐Chip Models of Human Liver Fibrosis
inferred← citeshttps://doi.org/10.1002/adma.202311474openalex-snapshot
Vicious Cycle‐Breaking Lipid Nanoparticles Remodeling Multicellular Crosstalk to Reverse Liver Fibrosis
inferred← citeshttps://doi.org/10.1002/advs.202304408openalex-snapshot
Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid
inferred← citeshttps://doi.org/10.1002/advs.202408898openalex-snapshot
Pathological Microenvironment‐Remodeling Nanoparticles to Alleviate Liver Fibrosis: Reversing Hepatocytes‐Hepatic Stellate Cells Malignant Crosstalk
inferred← citeshttps://doi.org/10.1002/advs.202417332openalex-snapshot
Engineered Hydrogels for Organoid Models of Human Nonalcoholic Fatty Liver Disease
inferred← citeshttps://doi.org/10.1002/advs.202508751openalex-snapshot
AI‐Assisted Drug Re‐Purposing for Human Liver Fibrosis
inferred← citeshttps://doi.org/10.1002/btm2.10579openalex-snapshot
Prospective therapeutics for intestinal and hepatic fibrosis
inferred← citeshttps://doi.org/10.1002/cbdv.202402248openalex-snapshot
Research Progress on Natural Products Alleviating Liver Inflammation and Fibrosis via NF‐κB Pathway
inferred← citeshttps://doi.org/10.1002/cbic.202300002openalex-snapshot
Peptide‐Based Nanoarchitectonics for the Treatment of Liver Fibrosis
inferred← citeshttps://doi.org/10.1002/ccs3.12033openalex-snapshot
LncRNA Snhg12/IGFBP3 axis is involved in liver fibrosis by promoting the proliferation and activation of mouse hepatic stellate cells
inferred← citeshttps://doi.org/10.1002/ctm2.1325openalex-snapshot
Mitochondrial general control of amino acid synthesis 5 like 1 promotes nonalcoholic steatohepatitis development through ferroptosis‐induced formation of neutrophil extracellular traps
inferred← citeshttps://doi.org/10.1002/hep.32312openalex-snapshot
Digitizing DILI: Who can? RUCAM? RECAM?
inferred← citeshttps://doi.org/10.1002/jbt.23648openalex-snapshot
Tanshinone IIA regulates CCl4 induced liver fibrosis in C57BL/6J mice via the PI3K/Akt and Nrf2/HO‐1 signaling pathways
inferred← citeshttps://doi.org/10.1002/jlb.5mr0822-733rrropenalex-snapshot
γδ T cells: The potential role in liver disease and implications for cancer immunotherapy
inferred← citeshttps://doi.org/10.1002/jmri.70061openalex-snapshot
Multi‐Scale Spatial Heterogeneity of Liver Fibrosis Evaluated by MR Elastography in Rat Models
inferred← citeshttps://doi.org/10.1002/kjm2.12901openalex-snapshot
The role of artificial intelligence in the management of liver diseases
inferred← citeshttps://doi.org/10.1002/mco2.346openalex-snapshot
Cellular senescence primes liver fibrosis regression through Notch‐EZH2
inferred← citeshttps://doi.org/10.1002/mco2.70616openalex-snapshot
Stem Cell Therapy for Inflammatory Diseases: Progress, Challenges, and Future Directions
inferred← citeshttps://doi.org/10.1002/mef2.68openalex-snapshot
Label‐free Raman spectroscopy for the assessment of liver fibrosis
inferred← citeshttps://doi.org/10.1002/ptr.7959openalex-snapshot
Extracellular matrix turnover: phytochemicals target and modulate the dual role of matrix metalloproteinases ( MMPs ) in liver fibrosis
inferred← citeshttps://doi.org/10.1002/smll.202304675openalex-snapshot
Supramolecular Nanoarchitectonics Based on Antagonist Peptide Self‐Assembly for Treatment of Liver Fibrosis
inferred← citeshttps://doi.org/10.1002/smtd.202402247openalex-snapshot
Engineered Intelligent Microenvironment Responsive Prodrug Conjugates Navigated by Bioinspired Lipoproteins for Reversing Liver Fibrosis
inferred← citeshttps://doi.org/10.1007/978-1-0716-3207-9_14openalex-snapshot
Decellularization of the Human Liver to Generate Native Extracellular Matrix for Use in Automated Functional Assays with Stellate Cells
inferred← citeshttps://doi.org/10.1007/978-1-0716-3207-9_16openalex-snapshot
Single Cell Secretome Analyses of Hepatic Stellate Cells: Aiming for Single Cell Phenomics
inferred← citeshttps://doi.org/10.1007/978-1-0716-3207-9_18openalex-snapshot
Experimental Workflow for Preclinical Studies of Human Antifibrotic Therapies
inferred← citeshttps://doi.org/10.1007/978-3-031-32483-3_54openalex-snapshot
Alcoholic Fibrosis/Cirrhosis and Its Reversibility
inferred← citeshttps://doi.org/10.1007/s00018-026-06215-zopenalex-snapshot
FOS drives podocyte injury and renal fibrosis in diabetic kidney disease via direct Smad3 binding
inferred← citeshttps://doi.org/10.1007/s00109-023-02395-4openalex-snapshot
Metabolomics reveals that chronic restraint stress alleviates carbon tetrachloride-induced hepatic fibrosis through the INSR/PI3K/AKT/AMPK pathway
inferred← citeshttps://doi.org/10.1007/s00210-026-05903-8openalex-snapshot
Pioglitazone protects against thioacetamide-induced liver fibrosis via AMPK-mediated inhibition of the TGF-β/Smad fibrotic cascade
inferred← citeshttps://doi.org/10.1007/s00259-023-06577-7openalex-snapshot
Platelet-derived growth factor receptor β-targeted positron emission tomography imaging for the noninvasive monitoring of liver fibrosis
inferred← citeshttps://doi.org/10.1007/s00259-026-08167-9openalex-snapshot
Biodistribution and radiation dosimetry of the PDGFRβ targeting PET tracer [68Ga]Ga-ATH001
inferred← citeshttps://doi.org/10.1007/s00330-025-11842-4openalex-snapshot
Hepatocyte uptake ratio derived from T1 mapping for quantitative assessment of liver fibrosis
inferred← citeshttps://doi.org/10.1007/s10068-026-02236-3openalex-snapshot
Nutraceuticals for the prevention of liver fibrosis in metabolic dysfunction-associated steatotic liver disease (MASLD)
inferred← citeshttps://doi.org/10.1007/s10616-025-00738-2openalex-snapshot
Protective effects of Scutellaria barbata against hepatocyte apoptosis during hepatic fibrosis progression
inferred← citeshttps://doi.org/10.1007/s11033-022-07713-6openalex-snapshot
CRISPR/dCas9 for hepatic fibrosis therapy: implications and challenges
inferred← citeshttps://doi.org/10.1007/s11356-022-22051-7openalex-snapshot
Proanthocyanidins attenuated liver damage and suppressed fibrosis in CCl4-treated rats
inferred← citeshttps://doi.org/10.1007/s12015-023-10583-5openalex-snapshot
Multiple Dimensions of using Mesenchymal Stem Cells for Treating Liver Diseases: From Bench to Beside
inferred← citeshttps://doi.org/10.1007/s12015-023-10592-4openalex-snapshot
The Current Proceedings of PSC-Based Liver Fibrosis Therapy
inferred← citeshttps://doi.org/10.1007/s12033-024-01106-9openalex-snapshot
Mechanism of Si Ni San Combined with Astragalus in Treating Hepatic Fibrosis: A Network Pharmacology and Molecular Docking Study
inferred← citeshttps://doi.org/10.1007/s12072-025-11022-yopenalex-snapshot
TRIM26 deficiency promotes liver fibrosis progression by mediating macrophage polarization via the EZH2-STAT1 axis
inferred← citeshttps://doi.org/10.1007/s13105-023-00976-yopenalex-snapshot
Comprehensive analysis of epigenetic and epitranscriptomic genes’ expression in human NAFLD
inferred← citeshttps://doi.org/10.1007/s13205-026-04839-3openalex-snapshot
Integrative approach to alcohol-related liver fibrosis: natural compounds modulating oxidative stress and ferroptosis
inferred← citeshttps://doi.org/10.1007/s13770-024-00631-7openalex-snapshot
Effects of Mesenchymal Stem Cells-Derived Extracellular Vesicles on Inhibition of Hepatic Fibrosis by Delivering miR-200a
inferred← citeshttps://doi.org/10.1007/s13770-024-00641-5openalex-snapshot
Reducing Nogo-B Improves Hepatic Fibrosis by Inhibiting BACe1-Mediated Autophagy
inferred← citeshttps://doi.org/10.1016/b978-0-323-95262-0.00025-5openalex-snapshot
Liver sinusoidal cells in the diagnosis and treatment of liver diseases: Role of hepatic stellate cells
inferred← citeshttps://doi.org/10.1016/j.abb.2025.110341openalex-snapshot
Lactucin alleviates liver fibrosis by regulating the TLR4-MyD88-MAPK/NF-κB signaling pathway through intestinal flora
inferred← citeshttps://doi.org/10.1016/j.ajpath.2023.06.006openalex-snapshot
Stress and Liver Fibrogenesis
inferred← citeshttps://doi.org/10.1016/j.aohep.2023.101278openalex-snapshot
A data-driven approach to decode metabolic dysfunction-associated steatotic liver disease
inferred← citeshttps://doi.org/10.1016/j.bbrc.2023.04.011openalex-snapshot
HOXC8/TGF-β1 positive feedback loop promotes liver fibrosis and hepatic stellate cell activation via activating Smad2/Smad3 signaling
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152703openalex-snapshot
FAM3B activates hepatic stellate cells to accelerate hepatic fibrosis by promoting glucose metabolism
inferred← citeshttps://doi.org/10.1016/j.bbrc.2026.154237openalex-snapshot
Oleic acid modulates perilipin expression and lipid droplet contents in TGFβ1 activated HSCs
inferred← citeshttps://doi.org/10.1016/j.bcp.2023.115740openalex-snapshot
Targeting collagen homeostasis for the treatment of liver fibrosis: Opportunities and challenges
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116121openalex-snapshot
Sevelamer reverses liver fibrosis by deactivation of hepatic stellate cells
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2022.121817openalex-snapshot
Modelling fatty liver disease with mouse liver-derived multicellular spheroids
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2025.123503openalex-snapshot
Macrophage membrane-coated NIR light-photodegradable carbon nitride-based gene vectors for gas-gene therapy of liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.114472openalex-snapshot
Matrix metalloproteinases induce extracellular matrix degradation through various pathways to alleviate hepatic fibrosis
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115794openalex-snapshot
Qijia rougan formula ameliorates ECM deposition in hepatic fibrosis by regulating the JAK1/STAT6-microRNA-23a feedback loop in macrophage M2 polarization
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116848openalex-snapshot
Progress of mesenchymal stem cells (MSCs) & MSC-Exosomes combined with drugs intervention in liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117319openalex-snapshot
Protective effects of puerarin on metabolic diseases: Emphasis on the therapeutical effects and the underlying molecular mechanisms
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118249openalex-snapshot
Therapeutic implications of obeticholic acid, a farnesoid X receptor agonist, in the treatment of liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.bios.2026.118737openalex-snapshot
Double-target responsive FRET sensor based on DNA tetrahedron for robust detection of liver fibrosis-related mRNAs in activated hepatic stellate cells
inferred← citeshttps://doi.org/10.1016/j.bmcl.2023.129290openalex-snapshot
Discovery and development of benzene sulfonamide derivatives as anti-hepatic fibrosis agents
inferred← citeshttps://doi.org/10.1016/j.carbpol.2023.121637openalex-snapshot
Inulin-like polysaccharide ABWW may impede CCl4 induced hepatic stellate cell activation through mediating the FAK/PI3K/AKT signaling pathway in vitro & in vivo
inferred← citeshttps://doi.org/10.1016/j.cbi.2022.110251openalex-snapshot
Edaravone protects against liver fibrosis progression via decreasing the IL-1β secretion of macrophages
inferred← citeshttps://doi.org/10.1016/j.cbi.2024.111015openalex-snapshot
Lipopolysaccharide modification enhances the inhibitory effect of clodronate liposomes on hepatic fibrosis by depletion of macrophages and hepatic stellate cells
inferred← citeshttps://doi.org/10.1016/j.cbi.2024.111305openalex-snapshot
Exploring the mechanism of ursolic acid in preventing liver fibrosis and improving intestinal microbiota based on NOX2/NLRP3 inflammasome signaling pathway
inferred← citeshttps://doi.org/10.1016/j.cbi.2025.111480openalex-snapshot
Hypoxia-inducible factor-1 alpha (HIF-1α) inhibitor AMSP-30 m attenuates CCl4-induced liver fibrosis in mice by inhibiting the sonic hedgehog pathway
inferred← citeshttps://doi.org/10.1016/j.cej.2026.173910openalex-snapshot
Decoupling multicellular activation circuits: MPDA-mediated co-delivery of quercetin/simvastatin for potent hepatic fibrosis reversal
inferred← citeshttps://doi.org/10.1016/j.cellsig.2024.111430openalex-snapshot
Noncoding RNA network crosstalk in organ fibrosis
inferred← citeshttps://doi.org/10.1016/j.cgh.2022.05.056openalex-snapshot
Hydronidone for the Treatment of Liver Fibrosis Related to Chronic Hepatitis B: A Phase 2 Randomized Controlled Trial
inferred← citeshttps://doi.org/10.1016/j.cgh.2023.11.017openalex-snapshot
Regression of Liver Fibrosis in Patients on Hepatitis B Therapy Is Associated With Decreased Liver-Related Events
inferred← citeshttps://doi.org/10.1016/j.clinbiochem.2024.110861openalex-snapshot
Exploratory study of extracellular matrix biomarkers for non-invasive liver fibrosis staging: A machine learning approach with XGBoost and explainable AI
inferred← citeshttps://doi.org/10.1016/j.clinre.2023.102213openalex-snapshot
Difficulties in assessing portal hypertension in case of HVB-HVD co infection
inferred← citeshttps://doi.org/10.1016/j.colsurfa.2025.138791openalex-snapshot
Supramolecular carrier-free biological nanofibers for treatment of liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.dld.2023.07.010openalex-snapshot
Integrated analysis and validation of TRIM23/p53 signaling pathway in hepatic stellate cells ferroptosis and liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.dld.2024.07.004openalex-snapshot
CTHRC1 serves as an indicator in biliary atresia for evaluating the stage of liver fibrosis and predicting prognosis
inferred← citeshttps://doi.org/10.1016/j.ebiom.2022.104069openalex-snapshot
Safety, tolerability, and anti-fibrotic efficacy of the CBP/β-catenin inhibitor PRI-724 in patients with hepatitis C and B virus-induced liver cirrhosis: An investigator-initiated, open-label, non-randomised, multicentre, phase 1/2a study
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2026.120070openalex-snapshot
α-Ketoglutarate mitigates titanium dioxide nanoparticle-induced hepatotoxicity by reinforcing redox balance and PI3K-Akt activation
inferred← citeshttps://doi.org/10.1016/j.ejrad.2023.110912openalex-snapshot
Conventional and artificial intelligence-based computed tomography and magnetic resonance imaging quantitative techniques for non-invasive liver fibrosis staging
inferred← citeshttps://doi.org/10.1016/j.eujim.2026.102706openalex-snapshot
Elucidating the multi-target mechanisms of Danggui Biejia decoction against hepatic fibrosis: An integrated network pharmacology and experimental study
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2023.129052openalex-snapshot
Gut microbial dysbiosis is associated with metabolism and immune factors in liver fibrosis mice
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.137936openalex-snapshot
The structure elucidation and alleviating effect on liver fibrosis in vivo of a pectin-like polysaccharide isolated from Buddleja officinalis
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.111002openalex-snapshot
HSC-derived exosomal miR-199a-5p promotes HSC activation and hepatocyte EMT via targeting SIRT1 in hepatic fibrosis
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.111261openalex-snapshot
The combination of tetracyclines effectively ameliorates liver fibrosis via inhibition of EphB1/2
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.111598openalex-snapshot
Wuling capsule modulates macrophage polarization by inhibiting the TLR4-NF-κB signaling pathway to relieve liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113437openalex-snapshot
The role of macrophage-derived exosomes in noncancer liver diseases: From intercellular crosstalk to clinical potential
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.114100openalex-snapshot
Modulation of γδ T cells by USF3: Implications for liver fibrosis and immune regulation
inferred← citeshttps://doi.org/10.1016/j.isci.2023.106572openalex-snapshot
Expansion of macrophage and liver sinusoidal endothelial cell subpopulations during non-alcoholic steatohepatitis progression
inferred← citeshttps://doi.org/10.1016/j.isci.2025.112224openalex-snapshot
CT-based artificial intelligence system complementing deep learning model and radiologist for liver fibrosis staging
inferred← citeshttps://doi.org/10.1016/j.isci.2026.117372openalex-snapshot
Leveraging serum CHI3L1 and machine learning for non-invasive liver fibrosis diagnostics
inferred← citeshttps://doi.org/10.1016/j.jbc.2026.113366openalex-snapshot
Sirtuin five knockdown induced the ferroptosis of hepatic stellate cells in hepatic fibrosis progression through de-succinylation modification of GPX4
inferred← citeshttps://doi.org/10.1016/j.jceh.2023.09.001openalex-snapshot
Regulation of High-fat Diet-induced Liver Fibrosis by SOCS1 Expression in Hepatic Stellate Cells
inferred← citeshttps://doi.org/10.1016/j.jchromb.2026.125126openalex-snapshot
Rougan Granules ameliorates liver fibrosis through autophagy regulation: Insights from HPLC-Q-TOF-MS/MS, network pharmacology, and experimental validation
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2023.05.010openalex-snapshot
In Vivo and In Vitro Models to Study Liver Fibrosis: Mechanisms and Limitations
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2023.09.008openalex-snapshot
The Origin and Fate of Liver Myofibroblasts
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2023.09.010openalex-snapshot
Matrix Gla Protein, a New Target Fighting Against Fibrosis of Nonalcoholic Steatohepatitis?
inferred← citeshttps://doi.org/10.1016/j.jconrel.2026.114864openalex-snapshot
Nanotherapy targeting liver sinusoidal endothelial cells in liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.jconrel.2026.115026openalex-snapshot
Metabolism-modulating nanoparticles for remodeling adipose-liver crosstalk to reverse liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.jep.2023.116419openalex-snapshot
A herbal product inhibits carbon tetrachloride-induced liver fibrosis by suppressing the epidermal growth factor receptor signaling pathway
inferred← citeshttps://doi.org/10.1016/j.jep.2023.116870openalex-snapshot
Danggui Shaoyao San: Chemical characterization and inhibition of oxidative stress and inflammation to treat CCl4-induced hepatic fibrosis
inferred← citeshttps://doi.org/10.1016/j.jep.2023.117334openalex-snapshot
TMT-based proteomics analysis identifies the interventional mechanisms of Qijia Rougan decoction in improving hepatic fibrosis
inferred← citeshttps://doi.org/10.1016/j.jep.2023.117383openalex-snapshot
Bile acids metabolism involved in the beneficial effects of Danggui Shaoyao San via gut microbiota in the treatment of CCl4 induced hepatic fibrosis
inferred← citeshttps://doi.org/10.1016/j.jep.2023.117402openalex-snapshot
Dahuang zhechong pill ameliorates hepatic fibrosis by regulating gut microbiota and metabolites
inferred← citeshttps://doi.org/10.1016/j.jep.2024.118169openalex-snapshot
Ba-Qi-Rougan formula alleviates hepatic fibrosis by suppressing hepatic stellate cell activation via the MSMP/CCR2/PI3K pathway
inferred← citeshttps://doi.org/10.1016/j.jep.2024.118712openalex-snapshot
Experimental study on H2O2 activation of HSC-T6 and hepatic fibrosis in cholestatic mice by "Yajieshaba"
inferred← citeshttps://doi.org/10.1016/j.jep.2025.120488openalex-snapshot
Mechanism of Bao Gan Ning decoction in attenuating hepatic fibrosis via modulation of the gut microbiome and PPAR/CYP7A1-mediated bile acid metabolism
inferred← citeshttps://doi.org/10.1016/j.jep.2025.120812openalex-snapshot
Traditional uses, phytochemical constituents, pharmacological activities, toxicity, and quality control of Senecio cannabifolius Less.: A review
inferred← citeshttps://doi.org/10.1016/j.jep.2026.121759openalex-snapshot
Asarinin alleviates hepatic fibrosis through TRα-STAT3 pathway: A new strategy by regulating liver microenvironment
inferred← citeshttps://doi.org/10.1016/j.jfma.2025.12.042openalex-snapshot
Clinical implications of fibrosis marker dynamics after hepatitis C cure: Insights from paired biopsies
inferred← citeshttps://doi.org/10.1016/j.jfutfo.2026.06.023openalex-snapshot
Natural Flavonoids as Potential Modulators of Liver Fibrosis: A Review of Mechanisms and Therapeutic Targets
inferred← citeshttps://doi.org/10.1016/j.jhep.2024.01.032openalex-snapshot
Exploring the impact of the PNPLA3 I148M variant on primary human hepatic stellate cells using 3D extracellular matrix models
inferred← citeshttps://doi.org/10.1016/j.jhep.2024.06.028openalex-snapshot
Metabolic phenotyping of patients with advanced chronic liver disease for better characterization of cirrhosis regression
inferred← citeshttps://doi.org/10.1016/j.jhep.2024.07.034openalex-snapshot
Targeting the liver clock improves fibrosis by restoring TGF-β signaling
inferred← citeshttps://doi.org/10.1016/j.jhep.2026.07.018openalex-snapshot
Fibrosis regression in chronic liver disease: The pathologist’s view
inferred← citeshttps://doi.org/10.1016/j.jhepr.2026.101783openalex-snapshot
Single-cell fixed RNA profiling uncovers SEMA4D and LMCD1 as therapeutic targets in a liver fibrosis model
inferred← citeshttps://doi.org/10.1016/j.jhepr.2026.102020openalex-snapshot
MiR-122 regulates liver tolerance
inferred← citeshttps://doi.org/10.1016/j.jpha.2023.06.002openalex-snapshot
New discoveries in the field of metabolism by applying single-cell and spatial omics
inferred← citeshttps://doi.org/10.1016/j.jpha.2023.12.017openalex-snapshot
Cornus officinalis with high pressure wine steaming enhanced anti-hepatic fibrosis: Possible through SIRT3-AMPK axis
inferred← citeshttps://doi.org/10.1016/j.jprot.2024.105227openalex-snapshot
Network pharmacology combined with metabolomics to reveal the anti-fibrotic mechanism of Polygoni Orientalis Fructus in CCl4-induced hepatic fibrosis rats
inferred← citeshttps://doi.org/10.1016/j.mam.2023.101191openalex-snapshot
Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies
inferred← citeshttps://doi.org/10.1016/j.mam.2023.101231openalex-snapshot
Liver fibrosis in NAFLD/NASH: from pathophysiology towards diagnostic and therapeutic strategies
inferred← citeshttps://doi.org/10.1016/j.matbio.2025.11.007openalex-snapshot
CCN1: a SASPy protein that plays multifaceted roles in fibrogenesis
inferred← citeshttps://doi.org/10.1016/j.mbplus.2022.100127openalex-snapshot
Fibrosis resolution in the mouse liver: Role of Mmp12 and potential role of calpain 1/2
inferred← citeshttps://doi.org/10.1016/j.metabol.2023.155562openalex-snapshot
Loss of CEACAM1 in endothelial cells causes hepatic fibrosis
inferred← citeshttps://doi.org/10.1016/j.micres.2026.128602openalex-snapshot
Microbiota-fibroblasts interactions in multi-organ fibrosis
inferred← citeshttps://doi.org/10.1016/j.molmet.2024.101987openalex-snapshot
A review on cell-free RNA profiling: Insights into metabolic diseases and predictive value for bariatric surgery outcomes
inferred← citeshttps://doi.org/10.1016/j.mtadv.2023.100417openalex-snapshot
Hydrogel microneedle patch for treatment of liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.mtbio.2023.100711openalex-snapshot
Melanin inspired microcapsules delivering immune metabolites for hepatic fibrosis management
inferred← citeshttps://doi.org/10.1016/j.ncrna.2024.08.004openalex-snapshot
Plasma microRNA-15a/16-1 serves as a non-invasive indicator of liver fibrosis severity in individuals with chronic hepatitis B
inferred← citeshttps://doi.org/10.1016/j.phrs.2024.107245openalex-snapshot
The current landscape of antifibrotic therapy across different organs: A systematic approach
inferred← citeshttps://doi.org/10.1016/j.phrs.2026.108391openalex-snapshot
SLC25A1-targeted gene therapy attenuates liver fibrosis through NEDD4-mediated ubiquitination and degradation of PPARγ
inferred← citeshttps://doi.org/10.1016/j.phymed.2023.155148openalex-snapshot
Ginkgolic acid inhibits the expression of SAE1 and induces ferroptosis to exert an anti-hepatic fibrosis effect
inferred← citeshttps://doi.org/10.1016/j.phymed.2024.155916openalex-snapshot
Jiawei Taohe Chengqi Decoction attenuates CCl4 induced hepatic fibrosis by inhibiting HSCs activation via TGF-β1/CUGBP1 and IFN-γ/Smad7 pathway
inferred← citeshttps://doi.org/10.1016/j.phymed.2024.156144openalex-snapshot
Astilbin alleviates hepatic fibrosis through PXR-PINK1/Parkin pathway: A new strategy by regulating hepatic stellate cells-macrophage crosstalk
inferred← citeshttps://doi.org/10.1016/j.phymed.2024.156223openalex-snapshot
Ginsenoside compound K restrains hepatic fibrotic response by dual-inhibition of GLS1 and LDHA
inferred← citeshttps://doi.org/10.1016/j.phymed.2026.158431openalex-snapshot
Huaganjian decoction attenuates liver fibrosis via purine metabolic-inflammatory synergistic crosstalk: network pharmacology combined with multi-omics analyses
inferred← citeshttps://doi.org/10.1016/j.phymed.2026.158693openalex-snapshot
6-Shogaol attenuates liver fibrosis by driving hepatic stellate cell senescence through the cGAS-STING-NF-κB axis
inferred← citeshttps://doi.org/10.1016/j.phymed.2026.158863openalex-snapshot
Therapeutic efficacy and dosing regimen evidence synthesis of Ursolic Acid for liver injury: A preclinical systematic review with machine learning
inferred← citeshttps://doi.org/10.1016/j.prmcm.2026.100880openalex-snapshot
ShuXueNing injection alleviates liver fibrosis by inhibiting hepatic stellate cell activation and suppressing the EGFR/STAT3/HIF1A pathway
inferred← citeshttps://doi.org/10.1016/j.redox.2022.102286openalex-snapshot
Capacity of extracellular globins to reduce liver fibrosis via scavenging reactive oxygen species and promoting MMP-1 secretion
inferred← citeshttps://doi.org/10.1016/j.taap.2023.116438openalex-snapshot
Dihydrokaempferol attenuates CCl4-induced hepatic fibrosis by inhibiting PARP-1 to affect multiple downstream pathways and cytokines
inferred← citeshttps://doi.org/10.1016/j.tice.2026.103740openalex-snapshot
Dual regulatory roles and mechanisms of Gamma delta T cells in organ fibrosis
inferred← citeshttps://doi.org/10.1016/j.tjnut.2026.101683openalex-snapshot
Emerging Trends and Research Hotspots in Gut Microbiota–Liver Fibrosis Research (2008–2025): A Bibliometric Analysis
inferred← citeshttps://doi.org/10.1016/j.ultrasmedbio.2022.05.026openalex-snapshot
Viscoelasticity assessment for in vivo quantification of muscle contusion injury in rats using shear wave elastography
inferred← citeshttps://doi.org/10.1016/j.ultrasmedbio.2024.11.011openalex-snapshot
A Novel Nanoscale Phase-Change Contrast Agent Evaluates the Hepatic Fibrosis Through Targeting Hepatic Stellate Cell Platelet-Derived Factor Beta Receptor by Ultrasound in Vitro
inferred← citeshttps://doi.org/10.1016/j.virusres.2026.199698openalex-snapshot
RAB25 promotes hepatitis B virus-induced liver fibrosis progression through activation of the PI3K/AKT signaling pathway
inferred← citeshttps://doi.org/10.1016/j.xcrm.2026.103056openalex-snapshot
Targeting RPL4 improves the therapeutic efficacy of PD-L1 blockade in liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.yexcr.2024.113992openalex-snapshot
Notoginsenoside R1 targets PPAR-γ to inhibit hepatic stellate cell activation and ameliorates liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.yexcr.2026.115169openalex-snapshot
Deduhonghua-7 powder and its bioactive component luteolin alleviate hepatic fibrosis through CHRM3/NF-κB axis
inferred← citeshttps://doi.org/10.1016/s2468-1253(23)00111-5openalex-snapshot
Fibroblasts in liver cancer: functions and therapeutic translation
inferred← citeshttps://doi.org/10.1016/s2468-1253(23)00438-7openalex-snapshot
Pathophysiology and therapeutic options for cirrhotic portal hypertension
inferred← citeshttps://doi.org/10.1017/s000711452400237xopenalex-snapshot
Obesity and risk for liver disease: a two-sample Mendelian randomisation study
inferred← citeshttps://doi.org/10.1021/acs.jafc.4c00976openalex-snapshot
Aryl Hydrocarbon Receptor Activation Limits the Fatty Acid Synthesis and Subsequent “miR-193a-3p-HDAC3-FASN” Signals to Alleviate Intestinal Fibrosis
inferred← citeshttps://doi.org/10.1021/acs.jafc.4c03286openalex-snapshot
Raspberry Ketone Attenuates Hepatic Fibrogenesis and Inflammation via Regulating the Crosstalk of FXR and PGC-1α Signaling
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.4c00834openalex-snapshot
Discovery of Novel Peptide Antagonists Targeting GPR55 for Liver Inflammation and Fibrosis
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.4c01651openalex-snapshot
Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.4c02938openalex-snapshot
Discovery of Novel Cyclic Peptides as SMAD2–SMAD4 Interaction Inhibitors for the Treatment of Hepatic Fibrosis
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6c00375openalex-snapshot
Polycyclic-Fused Cytochalasins with Anti-Liver Fibrosis Activity Produced by the Endophytic Fungus Trichoderma harzianum
inferred← citeshttps://doi.org/10.1021/acsnano.4c15562openalex-snapshot
Circularized Supramolecular Spherical Nucleic Acids Alleviates Liver Fibrosis through Blocking Upstream Activation and Reversing Activation State of Hepatic Stellate Cells
inferred← citeshttps://doi.org/10.1038/s41392-023-01720-0openalex-snapshot
Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases
inferred← citeshttps://doi.org/10.1038/s41401-024-01351-3openalex-snapshot
Luteolin-7-diglucuronide, a novel PTP1B inhibitor, ameliorates hepatic stellate cell activation and liver fibrosis in mice
inferred← citeshttps://doi.org/10.1038/s41401-026-01908-4openalex-snapshot
Emerging roles of mitophagy in liver fibrosis: Implications for therapy
inferred← citeshttps://doi.org/10.1038/s41418-023-01130-3openalex-snapshot
DNA 5mC and RNA m6A modification successively facilitates the initiation and perpetuation stages of HSC activation in liver fibrosis progression
inferred← citeshttps://doi.org/10.1038/s41419-022-04802-zopenalex-snapshot
MyD88 in hepatic stellate cells enhances liver fibrosis via promoting macrophage M1 polarization
inferred← citeshttps://doi.org/10.1038/s41419-022-05527-9openalex-snapshot
USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells
inferred← citeshttps://doi.org/10.1038/s41419-023-05733-zopenalex-snapshot
The role of N-glycosylation modification in the pathogenesis of liver cancer
inferred← citeshttps://doi.org/10.1038/s41419-024-07063-0openalex-snapshot
Iron chelation as a new therapeutic approach to prevent senescence and liver fibrosis progression
inferred← citeshttps://doi.org/10.1038/s41467-023-37453-5openalex-snapshot
MAIT cell inhibition promotes liver fibrosis regression via macrophage phenotype reprogramming
inferred← citeshttps://doi.org/10.1038/s41467-024-52308-3openalex-snapshot
A FAPα-activated MRI nanoprobe for precise grading diagnosis of clinical liver fibrosis
inferred← citeshttps://doi.org/10.1038/s41538-024-00334-2openalex-snapshot
Ampelopsis grossedentata tea alleviating liver fibrosis in BDL-induced mice via gut microbiota and metabolite modulation
inferred← citeshttps://doi.org/10.1038/s41577-026-01335-wopenalex-snapshot
Immune surveillance and immune evasion of senescent cells
inferred← citeshttps://doi.org/10.1038/s41591-023-02602-2openalex-snapshot
An integrated gene-to-outcome multimodal database for metabolic dysfunction-associated steatotic liver disease
inferred← citeshttps://doi.org/10.1038/s41598-023-36867-xopenalex-snapshot
The plasma degradome reflects later development of NASH fibrosis after liver transplant
inferred← citeshttps://doi.org/10.1038/s41598-023-39641-1openalex-snapshot
Serum folate associated with nonalcoholic fatty liver disease and advanced hepatic fibrosis
inferred← citeshttps://doi.org/10.1038/s41598-025-11606-6openalex-snapshot
Identification of CTSK as a TLR-related critical biomarker in liver cirrhosis via integrative bioinformatics and pathological characterization
inferred← citeshttps://doi.org/10.1038/s41598-025-86176-8openalex-snapshot
Association between overt hepatic encephalopathy and liver pathology after transjugular intrahepatic portosystemic shunt creation in cirrhotic patients
inferred← citeshttps://doi.org/10.1038/s41598-025-87427-4openalex-snapshot
A machine learning based algorithm accurately stages liver disease by quantification of arteries
inferred← citeshttps://doi.org/10.1038/s41598-025-96699-9openalex-snapshot
Histone methyltransferase SMYD2 regulates the activation of hepatic stellate cells by activating TLR4 signaling
inferred← citeshttps://doi.org/10.1038/s41598-025-98680-yopenalex-snapshot
Investigating hepatic fibrosis heterogeneity by three-dimensional imaging in metabolic dysfunction-associated steatotic liver disease
inferred← citeshttps://doi.org/10.1038/s42003-023-05552-0openalex-snapshot
Selectivity matters: selective ROCK2 inhibitor ameliorates established liver fibrosis via targeting inflammation, fibrosis, and metabolism
inferred← citeshttps://doi.org/10.1038/s42255-023-00896-7openalex-snapshot
Upregulation of WDR6 drives hepatic de novo lipogenesis in insulin resistance in mice
inferred← citeshttps://doi.org/10.1038/s43856-026-01704-5openalex-snapshot
Emerging signal transduction pathways and the role of bacterial extracellular vesicles linked to the pathogenesis of endometriosis
inferred← citeshttps://doi.org/10.1038/s44321-025-00230-6openalex-snapshot
Spatial gene regulatory networks driving cell state transitions during human liver disease
inferred← citeshttps://doi.org/10.1039/d3bm01926hopenalex-snapshot
Dynamic monitoring of the fibrosis disease by a collagen targeting near infrared probe
inferred← citeshttps://doi.org/10.1039/d3fo03858kopenalex-snapshot
Naringin ameliorates liver fibrosis in zebrafish by modulating IDO1-mediated lipid metabolism and inflammatory infiltration
inferred← citeshttps://doi.org/10.1039/d4fo03898copenalex-snapshot
Dietary supplementation of pterostilbene, a major component in small berries, prevents alcohol-induced liver injury associated with lipid accumulation and inflammation
inferred← citeshttps://doi.org/10.1039/d5mo00083aopenalex-snapshot
Prunus mongolica oil attenuates hepatic fibrosis via a lncRNA-mediated ceRNA network targeting dual PGC-1α/PPARγ and TGF-β/Smad3 pathways
inferred← citeshttps://doi.org/10.1055/a-2696-1032openalex-snapshot
Ovatodiolide: Recent Advances in Pharmacological Activities and Mechanisms
inferred← citeshttps://doi.org/10.1080/1061186x.2024.2347365openalex-snapshot
Roles and therapeutic targeting of dendritic cells in liver fibrosis
inferred← citeshttps://doi.org/10.1080/14728214.2024.2341878openalex-snapshot
Emerging synthetic drugs for the treatment of hepatic cirrhosis: a 2024 update
inferred← citeshttps://doi.org/10.1080/14728222.2023.2258280openalex-snapshot
Galectin-3: therapeutic targeting in liver disease
inferred← citeshttps://doi.org/10.1080/14786419.2024.2391071openalex-snapshot
Elucidation of the anti-fibrotic diseases mechanism of chelerythrine by integrative approach of network pharmacology and experimental verification
inferred← citeshttps://doi.org/10.1080/15376516.2024.2349551openalex-snapshot
Farnesoid X receptor modulator 12β-( m -methyl-benzoyl)-11,12-dihydro oleanolic acid represses liver fibrosis by inhibiting ERK/p38 signaling pathways
inferred← citeshttps://doi.org/10.1080/17474124.2025.2508963openalex-snapshot
Reviewing the function of macrophages in liver disease
inferred← citeshttps://doi.org/10.1084/jem.20251114openalex-snapshot
Tet2 deficiency–induced expansion of monocyte-derived macrophages promotes liver fibrosis
inferred← citeshttps://doi.org/10.1089/rej.2024.0053openalex-snapshot
Wedelolactone Attenuates Liver Fibrosis and Hepatic Stellate Cell Activation by Suppressing the Hippo Pathway
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