On the public citation graph
Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S‐phase arrest, in human myeloma cells
0 signed · 104 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/1097-0142(20000615)88:12+<3022::aid-cncr19>3.0.co;2-ropenalex-snapshot
Bisphosphonates in multiple myeloma
inferredcites →https://doi.org/10.1002/jbmr.5650090211openalex-snapshot
Effect of the bisphosphonate risedronate on bone metastases in a rat mammary adenocarcinoma model system
inferredcites →https://doi.org/10.1006/abbi.1999.1502openalex-snapshot
Alendronate Is a Specific, Nanomolar Inhibitor of Farnesyl Diphosphate Synthase
inferredcites →https://doi.org/10.1006/bbrc.1997.7145openalex-snapshot
Novel Salvage Pathway Utilizing Farnesol and Geranylgeraniol for Protein Isoprenylation
inferredcites →https://doi.org/10.1006/bbrc.1999.1499openalex-snapshot
Farnesyl Pyrophosphate Synthase Is the Molecular Target of Nitrogen-Containing Bisphosphonates
inferredcites →https://doi.org/10.1016/8756-3282(93)90187-fopenalex-snapshot
Histomorphometric effect of six month treatment with oral risedronate in patients with multiple myeloma
inferredcites →https://doi.org/10.1016/8756-3282(94)90890-7openalex-snapshot
Biologic, histologic and densitometric effects of oral risedronate on bone in patients with multiple myeloma
inferredcites →https://doi.org/10.1016/j.bone.2005.04.021openalex-snapshot
Phosphonocarboxylate inhibitors of Rab geranylgeranyl transferase disrupt the prenylation and membrane localization of Rab proteins in osteoclasts in vitro and in vivo
inferredcites →https://doi.org/10.1016/j.bone.2005.05.003openalex-snapshot
Novel insights into actions of bisphosphonates on bone: Differences in interactions with hydroxyapatite
inferredcites →https://doi.org/10.1016/s0026-895x(24)12827-1openalex-snapshot
Nitrogen-Bisphosphonates Block Retinoblastoma Phosphorylation and Cell Growth by Inhibiting the Cholesterol Biosynthetic Pathway in a Keratinocyte Model for Esophageal Irritation
inferredcites →https://doi.org/10.1016/s0074-7696(08)62312-8openalex-snapshot
Cell Death: The Significance of Apoptosis
inferredcites →https://doi.org/10.1016/s0898-6568(03)00007-xopenalex-snapshot
Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway
inferredcites →https://doi.org/10.1016/s0898-6568(97)00120-4openalex-snapshot
Membrane Association and Targeting of Prenylated Ras-like GTPases
inferredcites →https://doi.org/10.1016/s8756-3282(98)00120-3openalex-snapshot
Binding and antiresorptive properties of heterocycle-containing bisphosphonate analogs: structure-activity relationships
inferredcites →https://doi.org/10.1016/s8756-3282(99)00070-8openalex-snapshot
Molecular mechanisms of action of bisphosphonates
inferredcites →https://doi.org/10.1038/nm1125openalex-snapshot
The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers
inferredcites →https://doi.org/10.1038/sj.bjc.6602052openalex-snapshot
Nitrogen-containing bisphosphonates inhibit cell cycle progression in human melanoma cells
inferredcites →https://doi.org/10.1038/sj.leu.2400892openalex-snapshot
In vitro cytoreductive effects on multiple myeloma cells induced by bisphosphonates
inferredcites →https://doi.org/10.1038/sj.onc.1207039openalex-snapshot
Molecular analysis of transitional cell carcinoma using cDNA microarray
inferredcites →https://doi.org/10.1046/j.1365-2141.1997.2713086.xopenalex-snapshot
Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti‐tumour activity
inferredcites →https://doi.org/10.1046/j.1365-2141.2002.03824.xopenalex-snapshot
Pamidronate causes apoptosis of plasma cells in vivo in patients with multiple myeloma
inferredcites →https://doi.org/10.1054/bjoc.1999.1131openalex-snapshot
Bisphosphonates induce apoptosis in human breast cancer cell lines
inferredcites →https://doi.org/10.1054/bjoc.2001.1727openalex-snapshot
The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel
inferredcites →https://doi.org/10.1073/pnas.96.1.133openalex-snapshot
Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro
inferredcites →https://doi.org/10.1074/jbc.272.43.27224openalex-snapshot
The Geranylgeranyltransferase-I Inhibitor GGTI-298 Arrests Human Tumor Cells in G0/G1 and Induces p21WAF1/CIP1/SDI1 in a p53-independent Manner
inferredcites →https://doi.org/10.1074/jbc.m106473200openalex-snapshot
Identification of a Novel Phosphonocarboxylate Inhibitor of Rab Geranylgeranyl Transferase That Specifically Prevents Rab Prenylation in Osteoclasts and Macrophages
inferredcites →https://doi.org/10.1097/01.ju.0000070685.34760.5fopenalex-snapshot
Nitrogen Containing Bisphosphonates Induce Apoptosis and Inhibit the Mevalonate Pathway, Impairing Ras Membrane Localization in Prostate Cancer Cells
inferredcites →https://doi.org/10.1124/jpet.102.035295openalex-snapshot
Novel Antiangiogenic Effects of the Bisphosphonate Compound Zoledronic Acid
inferredcites →https://doi.org/10.1126/science.7652575openalex-snapshot
An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1
inferredcites →https://doi.org/10.1126/science.8456312openalex-snapshot
Protein Prenylation: a Mediator of Protein-Protein Interactions
inferredcites →https://doi.org/10.1126/stke.2502004re13openalex-snapshot
Human RAS Superfamily Proteins and Related GTPases
inferredcites →https://doi.org/10.1146/annurev.pharmtox.38.1.375openalex-snapshot
MECHANISMS OF ACTION OF BISPHOSPHONATES
inferredcites →https://doi.org/10.1158/0008-5472.can-05-0573openalex-snapshot
Emerging Role of RAB GTPases in Cancer and Human Disease
inferredcites →https://doi.org/10.1359/jbmr.1998.13.11.1668openalex-snapshot
Heterocycle-Containing Bisphosphonates Cause Apoptosis and Inhibit Bone Resorption by Preventing Protein Prenylation: Evidence from Structure-Activity Relationships in J774 Macrophages
inferredcites →https://doi.org/10.1359/jbmr.1998.13.4.581openalex-snapshot
Nitrogen-Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post-Translational Prenylation of GTP-Binding Proteins, Including Ras
inferredcites →https://doi.org/10.1359/jbmr.1999.14.12.2048openalex-snapshot
Zoledronate Is a Potent Inhibitor of Myeloma Cell Growth and Secretion of IL-6 and MMP-1 by the Tumoral Environment
inferredcites →https://doi.org/10.1359/jbmr.1999.14.5.722openalex-snapshot
The Role of Geranylgeranylation in Bone Resorption and Its Suppression by Bisphosphonates in Fetal Bone Explants In Vitro: A Clue to the Mechanism of Action of Nitrogen-Containing Bisphosphonates
inferredcites →https://doi.org/10.1359/jbmr.2000.15.11.2211openalex-snapshot
Bisphosphonates Induce Breast Cancer Cell Death In Vitro
inferredcites →https://doi.org/10.1359/jbmr.2003.18.3.482openalex-snapshot
Zoledronic Acid Treatment of 5T2MM-Bearing Mice Inhibits the Development of Myeloma Bone Disease: Evidence for Decreased Osteolysis, Tumor Burden and Angiogenesis, and Increased Survival
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/9783527672240.ch10openalex-snapshot
Phosphorus in Chemical Biology and Medicinal Chemistry
inferred← citeshttps://doi.org/10.1002/hc.20656openalex-snapshot
Synthesis of novel aminomethylenebisphosphonates and bisphosphonic acids, containing adamantyl fragment
inferred← citeshttps://doi.org/10.1002/ijc.24758openalex-snapshot
The bisphosphonate zoledronic acid has antimyeloma activityin vivoby inhibition of protein prenylation
inferred← citeshttps://doi.org/10.1002/mds.28605openalex-snapshot
Dysfunction of RAB39B‐ Mediated Vesicular Trafficking in Lewy Body Diseases
inferred← citeshttps://doi.org/10.1007/7081_2008_14openalex-snapshot
Biological Activity of Aminophosphonic Acids and Their Short Peptides
inferred← citeshttps://doi.org/10.1007/978-1-4419-9495-0_1openalex-snapshot
Osteoimmunology: The Bone-Immune Crosstalk
inferred← citeshttps://doi.org/10.1007/978-1-4614-6438-9_101635-1openalex-snapshot
Rab Geranylgeranyltransferase
inferred← citeshttps://doi.org/10.1007/978-3-319-67199-4_101635openalex-snapshot
Rab Geranylgeranyltransferase
inferred← citeshttps://doi.org/10.1007/s11745-009-3344-0openalex-snapshot
Suppression in Mevalonate Synthesis Mediates Antitumor Effects of Combined Statin and γ‐Tocotrienol Treatment
inferred← citeshttps://doi.org/10.1007/s11914-011-0061-4openalex-snapshot
Choosing a Treatment for Patients at the Time a Fracture is Presented
inferred← citeshttps://doi.org/10.1007/s42823-023-00603-2openalex-snapshot
Design, synthesis and biological studies of tetrazole fused imidazopyridines
inferred← citeshttps://doi.org/10.1016/b978-0-12-415922-8.00008-2openalex-snapshot
Inhibition of Rab Prenylation
inferred← citeshttps://doi.org/10.1016/b978-0-12-816434-1.00001-2openalex-snapshot
Efflux transporters in cancer resistance: Molecular and functional characterization of P-glycoprotein
inferred← citeshttps://doi.org/10.1016/j.bbrc.2008.09.157openalex-snapshot
Geranylgeranyl transferase type II inhibition prevents myeloma bone disease
inferred← citeshttps://doi.org/10.1016/j.bmc.2008.08.024openalex-snapshot
Synthesis and biological evaluation of indolyl bisphosphonates as anti-bone resorptive and anti-leishmanial agents
inferred← citeshttps://doi.org/10.1016/j.bone.2009.01.010openalex-snapshot
The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts
inferred← citeshttps://doi.org/10.1016/j.bone.2011.03.686openalex-snapshot
The gunmetal mouse reveals Rab geranylgeranyl transferase to be the major molecular target of phosphonocarboxylate analogues of bisphosphonates
inferred← citeshttps://doi.org/10.1016/j.bone.2011.03.774openalex-snapshot
The relationship between the chemistry and biological activity of the bisphosphonates
inferred← citeshttps://doi.org/10.1016/j.cdc.2023.101001openalex-snapshot
Design, synthesis and biological evaluation of amide derivatives of isoxazole-imidazo[1,2-a]pyridine as anticancer agents
inferred← citeshttps://doi.org/10.1016/j.cdc.2023.101092openalex-snapshot
Synthesis and biological evaluation of tetrazole fused imidazopyridine derivatives as anticancer agents
inferred← citeshttps://doi.org/10.1016/j.coph.2006.03.005openalex-snapshot
Recent advances in understanding the mechanism of action of bisphosphonates
inferred← citeshttps://doi.org/10.1016/j.drudis.2017.03.012openalex-snapshot
Targeting Rabs as a novel therapeutic strategy for cancer therapy
inferred← citeshttps://doi.org/10.1016/j.ejmech.2011.04.063openalex-snapshot
Synthesis, stereochemistry and SAR of a series of minodronate analogues as RGGT inhibitors
inferred← citeshttps://doi.org/10.1016/j.ejmech.2014.06.062openalex-snapshot
Synthesis and characterization of novel phosphonocarboxylate inhibitors of RGGT
inferred← citeshttps://doi.org/10.1016/j.jfluchem.2011.03.011openalex-snapshot
1,4-Addition of tetraethyl fluoromethylenebisphosphonate to α,β-unsaturated compounds
inferred← citeshttps://doi.org/10.1016/j.joim.2024.01.002openalex-snapshot
Tocotrienol isoforms: The molecular mechanisms underlying their effects in cancer therapy and their implementation in clinical trials
inferred← citeshttps://doi.org/10.1016/j.jorganchem.2009.07.025openalex-snapshot
Insight into the mechanism of three component condensation leading to aminomethylenebisphosphonates
inferred← citeshttps://doi.org/10.1016/j.leukres.2009.06.035openalex-snapshot
Differential activities of thalidomide and isoprenoid biosynthetic pathway inhibitors in multiple myeloma cells
inferred← citeshttps://doi.org/10.1016/j.leukres.2010.08.008openalex-snapshot
Isoprenoid biosynthetic pathway inhibition disrupts monoclonal protein secretion and induces the unfolded protein response pathway in multiple myeloma cells
inferred← citeshttps://doi.org/10.1016/j.yexcr.2011.02.006openalex-snapshot
Inhibition of geranylgeranylation mediates sensitivity to CHOP-induced cell death of DLBCL cell lines
inferred← citeshttps://doi.org/10.1021/acs.jafc.5c17266openalex-snapshot
Unraveling the Mechanism of Perillyl Alcohol and Its Derivatives as Potent Antifungal Agents against Gray Mold
inferred← citeshttps://doi.org/10.1021/ja211305jopenalex-snapshot
Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase
inferred← citeshttps://doi.org/10.1021/jm0702884openalex-snapshot
Synthesis and Biological Evaluation of α-Halogenated Bisphosphonate and Phosphonocarboxylate Analogues of Risedronate
inferred← citeshttps://doi.org/10.1021/jm900232uopenalex-snapshot
Synthesis, Chiral High Performance Liquid Chromatographic Resolution and Enantiospecific Activity of a Potent New Geranylgeranyl Transferase Inhibitor, 2-Hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosphonopropionic Acid
inferred← citeshttps://doi.org/10.1038/cddis.2014.475openalex-snapshot
Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions
inferred← citeshttps://doi.org/10.1038/emboj.2008.164openalex-snapshot
Structures of RabGGTase–substrate/product complexes provide insights into the evolution of protein prenylation
inferred← citeshttps://doi.org/10.1038/leu.2011.282openalex-snapshot
Bisphosphonates as antimyeloma drugs
inferred← citeshttps://doi.org/10.1038/nprot.2007.401openalex-snapshot
Synthesis of a fluorescent analogue of geranylgeranyl pyrophosphate and its use in a high-throughput fluorometric assay for Rab geranylgeranyltransferase
inferred← citeshttps://doi.org/10.1038/s41392-023-01441-4openalex-snapshot
Targeting small GTPases: emerging grasps on previously untamable targets, pioneered by KRAS
inferred← citeshttps://doi.org/10.1038/s41598-018-32491-2openalex-snapshot
Pseudomonas aeruginosa ExoS Induces Intrinsic Apoptosis in Target Host Cells in a Manner That is Dependent on its GAP Domain Activity
inferred← citeshttps://doi.org/10.1039/c6ra28316kopenalex-snapshot
Chemical approaches to inhibitors of isoprenoid biosynthesis: targeting farnesyl and geranylgeranyl pyrophosphate synthases
inferred← citeshttps://doi.org/10.1042/bst20120199openalex-snapshot
Novel functions for Rab GTPases in multiple aspects of tumour progression
inferred← citeshttps://doi.org/10.1074/jbc.m900579200openalex-snapshot
Structure of the Disordered C Terminus of Rab7 GTPase Induced by Binding to the Rab Geranylgeranyl Transferase Catalytic Complex Reveals the Mechanism of Rab Prenylation
inferred← citeshttps://doi.org/10.1080/00397910802005273openalex-snapshot
Synthesis of Novelbis-Phosphonate Derivatives by Pudovik Reaction
inferred← citeshttps://doi.org/10.1080/02841860802314696openalex-snapshot
Proteomic analysis of protein expression in human tonsillar cancer differentially expressed proteins characterize human tonsillar cancer
inferred← citeshttps://doi.org/10.1080/10426500801938592openalex-snapshot
The Preparation and Anticancer Activity of Some Phosphorus Heterocycles
inferred← citeshttps://doi.org/10.1080/10426507.2017.1417299openalex-snapshot
Synthesis and characterization of novel 1,2,3-triazoles containing a 1-hydroxyalkane-1,1-bisphosphonate substituent
inferred← citeshttps://doi.org/10.1097/jto.0b013e31824c7d43openalex-snapshot
Zoledronic Acid Produces Antitumor Effects on Mesothelioma Through Apoptosis and S-Phase Arrest in p53-Independent and Ras prenylation-Independent Manners
inferred← citeshttps://doi.org/10.1111/j.1365-2141.2008.07037.xopenalex-snapshot
Genes associated with the tumour microenvironment are differentially expressed in curedversusprimary chemotherapy‐refractory diffuse large B‐cell lymphoma
inferred← citeshttps://doi.org/10.1124/jpet.106.116467openalex-snapshot
Apomine Enhances the Antitumor Effects of Lovastatin on Myeloma Cells by Down-Regulating 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase
inferred← citeshttps://doi.org/10.1138/20080341openalex-snapshot
An update on the pharmacology of bisphosphonates and analogues with lower bone affinity
inferred← citeshttps://doi.org/10.1158/0008-5472.can-08-2195openalex-snapshot
Lowering Bone Mineral Affinity of Bisphosphonates as a Therapeutic Strategy to Optimize Skeletal Tumor Growth Inhibition In vivo
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-06-0843openalex-snapshot
Molecular Mechanisms of Action of Bisphosphonates: Current Status
inferred← citeshttps://doi.org/10.1359/jbmr.091009openalex-snapshot
Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo
inferred← citeshttps://doi.org/10.1371/journal.pone.0048871openalex-snapshot
Osteoclasts in Multiple Myeloma Are Derived from Gr-1+CD11b+Myeloid-Derived Suppressor Cells
inferred← citeshttps://doi.org/10.1634/theoncologist.2010-0225openalex-snapshot
The Role of Bisphosphonates in Multiple Myeloma: Mechanisms, Side Effects, and the Future
inferred← citeshttps://doi.org/10.21767/2471-8084.100006openalex-snapshot
Onco-Golgi: Is Fragmentation a Gate to Cancer Progression?
inferred← citeshttps://doi.org/10.3389/fcell.2024.1350097openalex-snapshot
Membrane trafficking alterations in breast cancer progression
inferred← citeshttps://doi.org/10.3390/cells8030255openalex-snapshot
Drugging the Small GTPase Pathways in Cancer Treatment: Promises and Challenges
inferred← citeshttps://doi.org/10.3390/ijms24010111openalex-snapshot
Targeting the Isoprenoid Biosynthetic Pathway in Multiple Myeloma
inferred← citeshttps://doi.org/10.4172/2155-9864.1000281openalex-snapshot
Detection of the Impact of Bisphosphonate on Multiple Myeloma using Lactadherin
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.