On the public citation graph

Roles for HB-EGF in Mesenchymal Stromal Cell Proliferation and Differentiation During Skeletal Growth

0 signed · 77 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1526-968x(200002)26:2<145::aid-gene14>3.0.co;2-copenalex-snapshot

Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice

inferredcites →https://doi.org/10.1002/j.1460-2075.1994.tb06516.xopenalex-snapshot

Heparin‐binding EGF‐like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up‐regulates functional receptors and diphtheria toxin sensitivity.

inferredcites →https://doi.org/10.1002/jbmr.2385openalex-snapshot

The Type I BMP Receptor ACVR1/ALK2 is Required for Chondrogenesis During Development

inferredcites →https://doi.org/10.1002/jbmr.295openalex-snapshot

Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo

inferredcites →https://doi.org/10.1002/jbmr.502openalex-snapshot

The Critical Role of the Epidermal Growth Factor Receptor in Endochondral Ossification

inferredcites →https://doi.org/10.1016/j.bone.2017.04.006openalex-snapshot

Molecular bases of the crosstalk between bone and muscle

inferredcites →https://doi.org/10.1016/j.gastro.2005.05.054openalex-snapshot

HB-EGF Enhances Restitution After Intestinal Ischemia/Reperfusion via PI3K/Akt and MEK/ERK1/2 Activation

inferredcites →https://doi.org/10.1016/j.joca.2015.04.019openalex-snapshot

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is increased in osteoarthritis and regulates chondrocyte catabolic and anabolic activities

inferredcites →https://doi.org/10.1016/j.pathophys.2013.11.008openalex-snapshot

Heparin-binding EGF-like growth factor (HB-EGF) therapy for intestinal injury: Application and future prospects

inferredcites →https://doi.org/10.1016/j.semcdb.2014.03.004openalex-snapshot

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) and proteolytic processing by a disintegrin and metalloproteinases (ADAM): A regulator of several pathways

inferredcites →https://doi.org/10.1016/j.tibs.2015.03.012openalex-snapshot

Structural determinants of Smad function in TGF-β signaling

inferredcites →https://doi.org/10.1016/j.ydbio.2012.02.019openalex-snapshot

Wls-mediated Wnts differentially regulate distal limb patterning and tissue morphogenesis

inferredcites →https://doi.org/10.1038/boneres.2014.15openalex-snapshot

Reduced EGFR signaling enhances cartilage destruction in a mouse osteoarthritis model

inferredcites →https://doi.org/10.1038/cddis.2013.363openalex-snapshot

Heparin-binding EGF-like growth factor and miR-1192 exert opposite effect on Runx2-induced osteogenic differentiation

inferredcites →https://doi.org/10.1038/ncb2528openalex-snapshot

c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression

inferredcites →https://doi.org/10.1038/nm0102-35openalex-snapshot

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy

inferredcites →https://doi.org/10.1038/nmeth762openalex-snapshot

A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration

inferredcites →https://doi.org/10.1038/nrendo.2016.12openalex-snapshot

BMP signalling in skeletal development, disease and repair

inferredcites →https://doi.org/10.1038/nrm3434openalex-snapshot

TGFβ signalling in context

inferredcites →https://doi.org/10.1038/nrrheum.2011.23openalex-snapshot

Advances in osteoclast biology: old findings and new insights from mouse models

inferredcites →https://doi.org/10.1053/gast.2003.50097openalex-snapshot

Liver regeneration in heparin-binding EGF-like growth factor transgenic mice after partial hepatectomy

inferredcites →https://doi.org/10.1053/j.gastro.2009.03.060openalex-snapshot

Heparin-Binding EGF-Like Growth Factor Increases Intestinal Microvascular Blood Flow in Necrotizing Enterocolitis

inferredcites →https://doi.org/10.1053/j.gastro.2009.07.067openalex-snapshot

Transmembrane and Soluble Isoforms of Heparin-Binding Epidermal Growth Factor–Like Growth Factor Regulate Distinct Processes in the Pancreas

inferredcites →https://doi.org/10.1053/j.gastro.2012.05.034openalex-snapshot

A Role for the Epidermal Growth Factor Receptor Signaling in Development of Intestinal Serrated Polyps in Mice and Humans

inferredcites →https://doi.org/10.1073/pnas.0537588100openalex-snapshot

Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function

inferredcites →https://doi.org/10.1073/pnas.1608938113openalex-snapshot

EGFR signaling is critical for maintaining the superficial layer of articular cartilage and preventing osteoarthritis initiation

inferredcites →https://doi.org/10.1073/pnas.90.9.3889openalex-snapshot

Appearance of heparin-binding EGF-like growth factor in wound fluid as a response to injury.

inferredcites →https://doi.org/10.1074/jbc.m403114200openalex-snapshot

Epidermal Growth Factor Receptor-deficient Mice Have Delayed Primary Endochondral Ossification Because of Defective Osteoclast Recruitment

inferredcites →https://doi.org/10.1089/ten.tea.2013.0679openalex-snapshot

Delivering Heparin-Binding Insulin-Like Growth Factor 1 with Self-Assembling Peptide Hydrogels

inferredcites →https://doi.org/10.1093/emboj/16.6.1268openalex-snapshot

Activation of HER4 by heparin‐binding EGF‐like growth factor stimulates chemotaxis but not proliferation

inferredcites →https://doi.org/10.1093/emboj/17.24.7260openalex-snapshot

A metalloprotease–disintegrin, MDC9/meltrin‐γ/ADAM9 and PKCδ are involved in TPA‐induced ectodomain shedding of membrane‐anchored heparin‐binding EGF‐like growth factor

inferredcites →https://doi.org/10.1093/emboj/cdg264openalex-snapshot

Defective valvulogenesis in HB‐EGF and TACE‐null mice is associated with aberrant BMP signaling

inferredcites →https://doi.org/10.1101/cshperspect.a021899openalex-snapshot

Bone Morphogenetic Proteins

inferredcites →https://doi.org/10.1101/gad.1824809openalex-snapshot

ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis

inferredcites →https://doi.org/10.1111/j.1349-7006.2007.00676.xopenalex-snapshot

Membrane‐anchored growth factors, the epidermal growth factor family: Beyond receptor ligands

inferredcites →https://doi.org/10.1126/science.1840698openalex-snapshot

A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF

inferredcites →https://doi.org/10.1128/mcb.00291-13openalex-snapshot

ADAM17 Controls Endochondral Ossification by Regulating Terminal Differentiation of Chondrocytes

inferredcites →https://doi.org/10.1242/dev.00491openalex-snapshot

Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth

inferredcites →https://doi.org/10.1242/dev.02030openalex-snapshot

HB-EGF promotes epithelial cell migration in eyelid development

inferredcites →https://doi.org/10.1242/dev.029926openalex-snapshot

BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation

inferredcites →https://doi.org/10.14670/hh-24.1593openalex-snapshot

Signaling pathways governing osteoblast proliferation, differentiation and function.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4605957openalex-extracted

Unraveling the Unexplored Complexity of Osteoporosis: Deciphering Targeted Therapeutic Strategies Through Integrated Bioinformatics Analysis of Single-Cell Rna Sequencing, Differential Mirna Expression, and Drug Interactions

inferred← citeshttps://doi.org/10.1002/adhm.202502771openalex-snapshot

A Heparin‐Functionalized Scaffold with HB‐EGF Immobilization for Tissue Engineering

inferred← citeshttps://doi.org/10.1002/biof.1709openalex-snapshot

Epidermal growth factor/epidermal growth factor receptor moves into the osteoblasts' cell nuclei where it is involved to regulate STAT5 's signaling

inferred← citeshttps://doi.org/10.1002/dvdy.438openalex-snapshot

Cross‐talk between EGFR and BMP signals regulates chondrocyte maturation during endochondral ossification

inferred← citeshttps://doi.org/10.1002/stem.3125openalex-snapshot

The noncanonical BMP signaling pathway plays an important role in club cell regeneration

inferred← citeshttps://doi.org/10.1002/tox.24391openalex-snapshot

The Increased Apoptosis of Mesenchymal Stem Cells Mediated Osteopenia Due to Prenatal Nicotine Exposure in Female Offspring Rats via IGF1 Pathway

inferred← citeshttps://doi.org/10.1007/s43032-024-01454-6openalex-snapshot

The Multiple Functions of HB-EGF in Female Reproduction and Related Cancer: Molecular Mechanisms and Targeting Strategies

inferred← citeshttps://doi.org/10.1016/j.bcp.2026.118116openalex-snapshot

The dual roles of EGFR signaling in skeletal homeostasis: from bone remodeling to cartilage metabolism and differentiated targeting strategies

inferred← citeshttps://doi.org/10.1016/j.bioactmat.2026.07.050openalex-snapshot

Loss of EGFR activity in skeletal stem/progenitor cells is associated with impaired fracture healing in aged mice

inferred← citeshttps://doi.org/10.1016/j.bioadv.2026.214720openalex-snapshot

Regulation of osteogenic differentiation of boronized Ti6Al4V/HA composite involving TRIP13-PI3K/Akt signaling pathway

inferred← citeshttps://doi.org/10.1016/j.biochi.2026.02.012openalex-snapshot

Multiple strategies for HB-EGF inhibition: interference with receptor binding, ectodomain shedding and matricrine signaling

inferred← citeshttps://doi.org/10.1016/j.ejps.2023.106394openalex-snapshot

Carbon quantum dots as a nitric oxide donor can promote wound healing of deep partial-thickness burns in rats

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e40469openalex-snapshot

WITHDRAWN: Unraveling the unexplored complexity of osteoporosis: deciphering targeted therapeutic strategies through integrated bioinformatics analysis, Mendelian randomization, and drug interactions

inferred← citeshttps://doi.org/10.1016/j.yexcr.2020.112299openalex-snapshot

Single-cell transcriptome profiling reveals the mechanism of abnormal proliferation of epithelial cells in congenital cystic adenomatoid malformation

inferred← citeshttps://doi.org/10.1038/s41375-021-01428-6openalex-snapshot

Circulating cytokines present in multiple myeloma patients inhibit the osteoblastic differentiation of adipose stem cells

inferred← citeshttps://doi.org/10.1038/s41390-021-01528-0openalex-snapshot

Blood protein profiles related to preterm birth and retinopathy of prematurity

inferred← citeshttps://doi.org/10.1080/07853890.2021.2015798openalex-snapshot

Epidermal growth factor signalling pathway in endochondral ossification: an evidence-based narrative review

inferred← citeshttps://doi.org/10.1080/09537104.2026.2642053openalex-snapshot

Platelet-rich plasma concentrations regulate MSCs osteogenesis via MAPK/PI3K–AKT pathways to mitigate inflammatory bone loss

inferred← citeshttps://doi.org/10.1093/jbmr/zjaf017openalex-snapshot

Epiregulin ameliorates ovariectomy-induced bone loss through orchestrating the differentiation of osteoblasts and osteoclasts

inferred← citeshttps://doi.org/10.1096/fj.201901145rropenalex-snapshot

Nicotine exposure during pregnancy programs osteopenia in male offspring rats via α4β2‐nAChR–p300‐ACE pathway

inferred← citeshttps://doi.org/10.1096/fj.202001945ropenalex-snapshot

Elevated HB‐EGF expression in neural stem cells causes middle age obesity by suppressing Hypocretin/Orexin expression

inferred← citeshttps://doi.org/10.1097/scs.0000000000009970openalex-snapshot

Artificial Dermis and Human Recombinant Epidermal Growth Factor Application for the Management of Critical Size Calvarial Defect

inferred← citeshttps://doi.org/10.1111/bph.15225openalex-snapshot

The low‐expression programming of 11β‐HSD2 mediates osteoporosis susceptibility induced by prenatal caffeine exposure in male offspring rats

inferred← citeshttps://doi.org/10.1126/scitranslmed.abb3946openalex-snapshot

Targeting cartilage EGFR pathway for osteoarthritis treatment

inferred← citeshttps://doi.org/10.1155/2022/4759172openalex-snapshot

Expression and Regulatory Network Analysis of BICC1 for Aged Sca-1-Positive Bone Narrow Mesenchymal Stem Cells

inferred← citeshttps://doi.org/10.1155/2022/6453501openalex-snapshot

Study on the Mechanism of Compound Kidney-Invigorating Granule for Osteoporosis based on Network Pharmacology and Experimental Verification

inferred← citeshttps://doi.org/10.1177/08853282221114450openalex-snapshot

Guided bone regeneration with extracellular matrix scaffold of small intestinal submucosa membrane

inferred← citeshttps://doi.org/10.1186/s13287-020-01790-9openalex-snapshot

Cellular senescence mediates the detrimental effect of prenatal dexamethasone exposure on postnatal long bone growth in mouse offspring

inferred← citeshttps://doi.org/10.21203/rs.3.rs-4979115/v1openalex-snapshot

Identification of Energy Metabolism and m6A-Related Gene Clusters in Kashin-Beck Disease Based on Bioinformatics Analysis

inferred← citeshttps://doi.org/10.2139/ssrn.5318533openalex-snapshot

Regulation of Osteogenic Differentiation Of Boronized Ti6al4v/Ha Compositevia Trip13-Pi3k/Akt Signaling Pathway

inferred← citeshttps://doi.org/10.3390/bioengineering11121307openalex-snapshot

RNA Sequencing Revealed a Weak Response of Gingival Fibroblasts Exposed to Hyaluronic Acid

inferred← citeshttps://doi.org/10.3390/ijms242417287openalex-snapshot

Interaction between Selected Adipokines and Musculoskeletal and Cardiovascular Systems: A Review of Current Knowledge

inferred← citeshttps://doi.org/10.4103/aja2024125openalex-snapshot

Exogenous administration of heparin-binding epidermal growth factor-like growth factor improves erectile function in mice with bilateral cavernous nerve injury

inferred← citeshttps://doi.org/10.7150/thno.115406openalex-snapshot

Overactivation of EGFR signaling in skeletal stem/progenitor cells promotes bone formation and repair

inferred← citeshttps://doi.org/10.7554/elife.50208openalex-snapshot

Activation of hedgehog signaling in mesenchymal stem cells induces cartilage and bone tumor formation via Wnt/β-Catenin

inferred← citeshttps://doi.org/10.7717/peerj.8907openalex-snapshot

Weighted gene correlation network analysis reveals novel biomarkers associated with mesenchymal stromal cell differentiation in early phase

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.