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Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non‐ketotic hyperglycinemia

https://doi.org/10.1002/jimd.12295
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1526-968x(200002)26:2<151::aid-gene17>3.0.co;2-eopenalex-snapshot
Hepatocyte-specific expression of Cre recombinase
inferredcites →https://doi.org/10.1002/ajmg.1320590410openalex-snapshot
Benzoate therapy and carnitine deficiency in non‐ketotic hyperglycinemia
inferredcites →https://doi.org/10.1002/ana.20853openalex-snapshot
Rapid diagnosis of glycine encephalopathy by 13C‐glycine breath test
inferredcites →https://doi.org/10.1002/ana.24485openalex-snapshot
Biochemical and molecular predictors for prognosis in nonketotic hyperglycinemia
inferredcites →https://doi.org/10.1002/bms.1200110609openalex-snapshot
The metabolism of cinnamic acid by healthy and phenylketonuric adults: A kinetic study
inferredcites →https://doi.org/10.1002/jat.2550040602openalex-snapshot
The occurrence, metabolism and toxicity of cinnamic acid and related compounds
inferredcites →https://doi.org/10.1006/mgme.2001.3257openalex-snapshot
Improving Treatment of Guanidinoacetate Methyltransferase Deficiency: Reduction of Guanidinoacetic Acid in Body Fluids by Arginine Restriction and Ornithine Supplementation
inferredcites →https://doi.org/10.1007/bf00237285openalex-snapshot
Gamma-D-glutamylglycine and cis-2,3-piperidine dicarboxylate as antagonists of excitatory amino acids in the hippocampus
inferredcites →https://doi.org/10.1007/s10545-005-0033-xopenalex-snapshot
Benzoate treatment and the glycine index in nonketotic hyperglycinaemia
inferredcites →https://doi.org/10.1007/s10545-011-9398-1openalex-snapshot
Prediction of long‐term outcome in glycine encephalopathy: a clinical survey
inferredcites →https://doi.org/10.1016/0163-7258(93)90022-6openalex-snapshot
The biochemistry and toxicology of benzoic acid metabolism and its relationship to the elimination of waste nitrogen
inferredcites →https://doi.org/10.1016/0278-6915(94)90085-xopenalex-snapshot
Metabolism of trans-cinnamic acid in the rat and the mouse and its variation with dose
inferredcites →https://doi.org/10.1016/0306-4522(86)90080-1openalex-snapshot
Mode of action of excitatory amino acid receptor antagonists on hippocampal long-lasting potentiation
inferredcites →https://doi.org/10.1016/0885-4505(86)90076-9openalex-snapshot
Acyl-CoA: Glycine N-acyltransferase: In vitro studies on the glycine conjugation of straight- and branched-chained acyl-CoA esters in human liver
inferredcites →https://doi.org/10.1016/b978-0-12-802896-4.00010-9openalex-snapshot
Cerebral creatine deficiency syndromes
inferredcites →https://doi.org/10.1016/j.celrep.2017.10.072openalex-snapshot
Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure
inferredcites →https://doi.org/10.1016/j.ejpn.2018.02.007openalex-snapshot
Treatment outcome of twenty-two patients with guanidinoacetate methyltransferase deficiency: An international retrospective cohort study
inferredcites →https://doi.org/10.1016/j.pharmthera.2012.05.003openalex-snapshot
The glycine deportation system and its pharmacological consequences
inferredcites →https://doi.org/10.1016/s0021-9258(18)76545-9openalex-snapshot
THE CONJUGATION OF BENZOIC ACID IN MAN
inferredcites →https://doi.org/10.1016/s0022-3476(69)80341-0openalex-snapshot
Nonketotic hyperglycinemia
inferredcites →https://doi.org/10.1016/s0022-3476(98)70365-8openalex-snapshot
Long-term use of high-dose benzoate and dextromethorphan for the treatment of nonketotic hyperglycinemia
inferredcites →https://doi.org/10.1016/s0887-8994(97)00083-0openalex-snapshot
Guanidinoacetate methyltransferase deficiency: New clinical features
inferredcites →https://doi.org/10.1021/pr300900bopenalex-snapshot
Hippurate: The Natural History of a Mammalian–Microbial Cometabolite
inferredcites →https://doi.org/10.1038/325529a0openalex-snapshot
Glycine potentiates the NMDA response in cultured mouse brain neurons
inferredcites →https://doi.org/10.1038/gim.2016.74openalex-snapshot
The genetic basis of classic nonketotic hyperglycinemia due to mutations in GLDC and AMT
inferredcites →https://doi.org/10.1038/ncomms7388openalex-snapshot
Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice
inferredcites →https://doi.org/10.1038/s41598-017-13722-4openalex-snapshot
Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome
inferredcites →https://doi.org/10.1042/bj1300495openalex-snapshot
Aromatic acids derived from phenylalanine in the tissues of rats with experimentally induced phenylketonuria-like characteristics
inferredcites →https://doi.org/10.1093/nar/gkw419openalex-snapshot
Heatmapper: web-enabled heat mapping for all
inferredcites →https://doi.org/10.1136/bmj.s1-4.13.256openalex-snapshot
M. Keller on the Conversion of Benzoic into Hippuric Acid
inferredcites →https://doi.org/10.1172/jci132360openalex-snapshot
Impaired folate 1-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase–deficient mice
inferredcites →https://doi.org/10.1177/095952874102400105openalex-snapshot
On Gouty Concretions, with a New Method of Treatment
inferredcites →https://doi.org/10.1620/tjem.159.147openalex-snapshot
Identification of benzoylcarnitine in the urine of a patient of hyperammonemia.
inferredcites →https://doi.org/10.2183/pjab.84.246openalex-snapshot
Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia
inferredcites →https://doi.org/10.2307/1005218openalex-snapshot
On the Conversion of Benzoic into Hippuric Acid
inferredcites →https://doi.org/10.3109/03602532.2014.908903openalex-snapshot
A new perspective on the importance of glycine conjugation in the metabolism of aromatic acids
inferredcites →https://doi.org/10.3233/pep-14096openalex-snapshot
Nonketotic hyperglycinemia and epilepsy

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Homozygosity for disease‐causing variants in AMT and GLDC in a patient with severe nonketotic hyperglycinemia
inferred← citeshttps://doi.org/10.1002/ana.26423openalex-snapshot
Integrative Approach to Predict Severity in Nonketotic Hyperglycinemia
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Cerebrospinal fluid amino acids glycine, serine, and threonine in nonketotic hyperglycinemia
inferred← citeshttps://doi.org/10.1002/jimd.70137openalex-snapshot
A Nonketotic Hyperglycinemia Mouse Shows Wide‐Ranging Biochemical Consequences of Elevated Glycine, Reduced Folate One‐Carbon Charging, and Serine Deficiency
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AAV-mediated expression of mouse or human GLDC normalises metabolic biomarkers in a GLDC-deficient mouse model of Non-Ketotic Hyperglycinemia
inferred← citeshttps://doi.org/10.1016/j.ymgme.2024.108594openalex-snapshot
The role of NMDA-receptor type glutamatergic antagonists dextromethorphan or ketamine in the treatment of nonketotic hyperglycinemia: A critical reassessment
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inferred← citeshttps://doi.org/10.1186/s13023-022-02581-6openalex-snapshot
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inferred← citeshttps://doi.org/10.3389/fgene.2022.854712openalex-snapshot
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FgGCV1, a glycine cleavage system T protein, regulates glycine metabolism and sexual reproduction in Fusarium graminearum
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Metabolic Rewiring and Altered Glial Differentiation in an iPSC-Derived Astrocyte Model Derived from a Nonketotic Hyperglycinemia Patient
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Notes from the 2022 Folate, Vitamin B12, and One-Carbon Metabolism Conference
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