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Characteristic ion clusters as determinants for the identification of pyrrolizidine alkaloid N‐oxides in pyrrolizidine alkaloid–containing natural products using HPLC–MS analysis
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1097-0231(19981030)12:20<1445::aid-rcm356>3.0.co;2-gopenalex-snapshot
Determination of hepatotoxic pyrrolizidine alkaloids by on-line high performance liquid chromatography mass spectrometry with an electrospray interface
inferredcites →https://doi.org/10.1002/jps.2600831010openalex-snapshot
Decomposition of ClozapineN-Oxide in the Qualitative and Quantitative Analysis of Clozapine and its Metabolites
inferredcites →https://doi.org/10.1002/pca.1314openalex-snapshot
Detection of High Levels of Pyrrolizidine‐N‐oxides in the Endangered Plant Cryptantha crassipes (Terlingua Creek Cat's‐eye) Using HPLC‐ESI‐MS
inferredcites →https://doi.org/10.1002/rcm.3398openalex-snapshot
Identification of five hepatotoxic pyrrolizidine alkaloids in a commonly used traditional Chinese medicinal herb, Herba Senecionis scandentis (Qianliguang)
inferredcites →https://doi.org/10.1002/rcm.3862openalex-snapshot
Simultaneous characterization of pyrrolizidine alkaloids and N ‐oxides in Gynura segetum by liquid chromatography/ion trap mass spectrometry
inferredcites →https://doi.org/10.1002/rcm.4329openalex-snapshot
Identification of metabolites of adonifoline, a hepatotoxic pyrrolizidine alkaloid, by liquid chromatography/tandem and high‐resolution mass spectrometry
inferredcites →https://doi.org/10.1007/s00216-009-3092-2openalex-snapshot
Update on analytical methods for toxic pyrrolizidine alkaloids
inferredcites →https://doi.org/10.1007/s00216-011-5075-3openalex-snapshot
The comparative pharmacokinetics of two pyrrolizidine alkaloids, senecionine and adonifoline, and their main metabolites in rats after intravenous and oral administration by UPLC/ESIMS
inferredcites →https://doi.org/10.1016/j.aca.2010.09.011openalex-snapshot
A new approach for simultaneous screening and quantification of toxic pyrrolizidine alkaloids in some potential pyrrolizidine alkaloid-containing plants by using ultra performance liquid chromatography–tandem quadrupole mass spectrometry
inferredcites →https://doi.org/10.1016/j.jhep.2010.07.031openalex-snapshot
Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum
inferredcites →https://doi.org/10.1016/j.jpba.2011.05.004openalex-snapshot
Authentication of Senecio scandens and S. vulgaris based on the comprehensive secondary metabolic patterns gained by UPLC–DAD/ESI-MS
inferredcites →https://doi.org/10.1016/j.toxlet.2004.11.010openalex-snapshot
Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid
inferredcites →https://doi.org/10.1016/j.toxlet.2011.06.020openalex-snapshot
Photoirradiation of dehydropyrrolizidine alkaloids—Formation of reactive oxygen species and induction of lipid peroxidation
inferredcites →https://doi.org/10.1016/s0031-9422(00)84554-9openalex-snapshot
Chemistry and Toxicology of Pyrrolizidine Alkaloids
inferredcites →https://doi.org/10.1016/s0090-9556(24)13677-xopenalex-snapshot
Characterization of Rat Liver Microsomal Metabolites of Clivorine, an Hepatotoxic Otonecine-Type Pyrrolizidine Alkaloid
inferredcites →https://doi.org/10.1016/s0378-4274(03)00293-5openalex-snapshot
Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine
inferredcites →https://doi.org/10.1021/tx0255370openalex-snapshot
Species Differences in the in Vitro Metabolic Activation of the Hepatotoxic Pyrrolizidine Alkaloid Clivorine
inferredcites →https://doi.org/10.1021/tx030030qopenalex-snapshot
Metabolic Formation of DHP-Derived DNA Adducts from a Representative Otonecine Type Pyrrolizidine Alkaloid Clivorine and the Extract of Ligularia hodgsonnii Hook
inferredcites →https://doi.org/10.1021/tx0340302openalex-snapshot
Gender Differences in Microsomal Metabolic Activation of Hepatotoxic Clivorine in Rat
inferredcites →https://doi.org/10.1055/s-0029-1185468openalex-snapshot
Qianliguang (Senecio scandens) Safety Dilemma: Dose Is the Key?
inferredcites →https://doi.org/10.1080/10590500701569414openalex-snapshot
Ginkgo BilobaLeave Extract: Biological, Medicinal, and Toxicological Effects
inferredcites →https://doi.org/10.1080/10590500902885676openalex-snapshot
Quality Assurance and Safety of Herbal Dietary Supplements
inferredcites →https://doi.org/10.1080/19440049.2011.603704openalex-snapshot
Screening of plant toxins in food, feed and botanicals using full-scan high-resolution (Orbitrap) mass spectrometry
inferredcites →https://doi.org/10.1081/dmr-120028426openalex-snapshot
Pyrrolizidine Alkaloids—Genotoxicity, Metabolism Enzymes, Metabolic Activation, and Mechanisms
inferredcites →https://doi.org/10.1177/0748233708093727openalex-snapshot
Metabolic activation of retronecine and retronecine N-oxide – formation of DHP-derived DNA adducts
inferredcites →https://doi.org/10.2174/138920011797470119openalex-snapshot
Hepatotoxicity and Tumorigenicity Induced by Metabolic Activation of Pyrrolizidine Alkaloids in Herbs
inferredcites →https://doi.org/10.2460/ajvr.1991.52.01.146openalex-snapshot
Toxicity of pyrrolizidine alkaloids from Riddell groundsel (Senecio riddellii) to cattle
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Chemotaxonomic investigation of Apocynaceae for retronecine-type pyrrolizidine alkaloids using HPLC-MS/MS
inferred← citeshttps://doi.org/10.1002/9781118992685.ch10openalex-snapshot
Pyrrolizidine Alkaloids in Food: Analytical, Toxicological and Health Considerations
inferred← citeshttps://doi.org/10.1002/jms.4532openalex-snapshot
Qualitative and quantitative analysis of pyrrolizidine alkaloids for the entire process quality control from Senecio scandens to Senecio scandens‐containing preparations by high performance liquid chromatography‐tandem mass spectrometry
inferred← citeshttps://doi.org/10.1002/jssc.202000776openalex-snapshot
LC/MS study of the diversity and distribution of pyrrolizidine alkaloids in Crotalaria species growing in Colombia
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Crotalaria spectabilis as a source of pyrrolizidine alkaloids and phenolic compounds: HPLC‐MS/MS dereplication and monocrotaline quantification of seed and leaf extracts
inferred← citeshttps://doi.org/10.1007/s00204-017-2013-yopenalex-snapshot
First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans
inferred← citeshttps://doi.org/10.1007/s00204-019-02499-2openalex-snapshot
Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids
inferred← citeshttps://doi.org/10.1007/s00216-013-7365-4openalex-snapshot
Structural screening by multiple reaction monitoring as a new approach for tandem mass spectrometry: presented for the determination of pyrrolizidine alkaloids in plants
inferred← citeshttps://doi.org/10.1007/s00216-014-8175-zopenalex-snapshot
An application of target profiling analyses in the hepatotoxicity assessment of herbal medicines: comparative characteristic fingerprint and bile acid profiling of Senecio vulgaris L. and Senecio scandens Buch.-Ham
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Alkaloid isolation methods and applications in agriculture and medicine
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Pyrrolizidine alkaloids and other constituents from Emilia fosbergii Nicolson
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Species difference in toxicokinetics and safety assessment of senecionine N-oxide in a UDP-glucuronosyltransferase 1A4 humanized mouse model
inferred← citeshttps://doi.org/10.1016/j.envpol.2020.115542openalex-snapshot
Comprehensive investigation and risk study on pyrrolizidine alkaloid contamination in Chinese retail honey
inferred← citeshttps://doi.org/10.1016/j.fct.2018.05.037openalex-snapshot
Determination and regulation of hepatotoxic pyrrolizidine alkaloids in food: A critical review of recent research
inferred← citeshttps://doi.org/10.1016/j.fct.2019.111107openalex-snapshot
Pyrrolizidine alkaloids in food and phytomedicine: Occurrence, exposure, toxicity, mechanisms, and risk assessment - A review
inferred← citeshttps://doi.org/10.1016/j.foodchem.2014.11.093openalex-snapshot
A novel ultra-performance liquid chromatography hyphenated with quadrupole time of flight mass spectrometry method for rapid estimation of total toxic retronecine-type of pyrrolizidine alkaloids in herbs without requiring corresponding standards
inferred← citeshttps://doi.org/10.1016/j.foodchem.2015.01.053openalex-snapshot
Characterization and screening of pyrrolizidine alkaloids and N-oxides from botanicals and dietary supplements using UHPLC-high resolution mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.foodchem.2022.135058openalex-snapshot
An analytical platform for the screening and identification of pyrrolizidine alkaloids in food matrices with high risk of contamination
inferred← citeshttps://doi.org/10.1016/j.foodcont.2017.10.026openalex-snapshot
Contamination of hepatotoxic pyrrolizidine alkaloids in retail honey in China
inferred← citeshttps://doi.org/10.1016/j.jchromb.2015.04.007openalex-snapshot
Effective application of freezing lipid precipitation and SCX-SPE for determination of pyrrolizidine alkaloids in high lipid foodstuffs by LC-ESI-MS/MS
inferred← citeshttps://doi.org/10.1016/j.jep.2013.09.010openalex-snapshot
Assessment of pyrrolizidine alkaloid-induced toxicity in an in vitro screening model
inferred← citeshttps://doi.org/10.1016/j.jep.2019.112421openalex-snapshot
Absorption difference between hepatotoxic pyrrolizidine alkaloids and their N-oxides – Mechanism and its potential toxic impact
inferred← citeshttps://doi.org/10.1016/j.jep.2023.117390openalex-snapshot
The toxicokinetic and metabolism of structurally diverse pyrrolizidine alkaloids in rats
inferred← citeshttps://doi.org/10.1016/j.jfda.2017.09.001openalex-snapshot
Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N -oxides
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2021.127706openalex-snapshot
Dietary alcohol exacerbates the hepatotoxicity induced by pyrrolizidine alkaloids: Hazard from food contamination
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Insight into pyrrolizidine alkaloids degradation and the chemical structures of their degradation products using ultra high performance liquid chromatography and Q-Exactive Orbitrap mass spectrometry
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An analytical strategy for discovering structural analogues of alkaloids in plant food using characteristic structural fragments extraction by high resolution orbitrap mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.phytol.2016.02.001openalex-snapshot
Lycopodium alkaloids from Lycopodium obscurum L. f. strictum
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Pyrrolizidine alkaloids in borage (Borago officinalis): Comprehensive profiling and development of a validated LC-MS/MS method for quantification
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.2c00292openalex-snapshot
From Structural Alerts to Signature Fragment Alerts: A Case Study on Pyrrolizidine Alkaloids
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.5b00253openalex-snapshot
Species-Specific Differences in thein VitroMetabolism of Lasiocarpine
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Lack of Metabolic Activation and Predominant Formation of an Excreted Metabolite of Nontoxic Platynecine-Type Pyrrolizidine Alkaloids
inferred← citeshttps://doi.org/10.1021/tx5002964openalex-snapshot
Identification of a New Reactive Metabolite of Pyrrolizidine Alkaloid Retrorsine: (3H-Pyrrolizin-7-yl)methanol
inferred← citeshttps://doi.org/10.1080/10590501.2015.1096882openalex-snapshot
Blood Pyrrole-Protein Adducts—A Biomarker of Pyrrolizidine Alkaloid-Induced Liver Injury in Humans
inferred← citeshttps://doi.org/10.1080/19440049.2014.900193openalex-snapshot
Investigation of targeted pyrrolizidine alkaloids in traditional Chinese medicines and selected herbal teas sourced in Ireland using LC-ESI-MS/MS
inferred← citeshttps://doi.org/10.1080/19440049.2020.1757166openalex-snapshot
Pyrrolizidine alkaloid profiling of four Boraginaceae species from Northern Germany and implications for the analytical scope proposed for monitoring of maximum levels
inferred← citeshttps://doi.org/10.1590/2175-7860202071118openalex-snapshot
A botanical census on pyrrolizidine alkaloid-producing species in Brazilian herbaria: data set for a potential health risk indication
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Establishing mass spectral fragmentation patterns for characterization of 1,2 -unsaturated pyrrolizidine alkaloids and N-oxides in Boraginaceae species from Macedonia using LC-ESI-MS/MS
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Phosphocreatine attenuates Gynura segetum-induced hepatocyte apoptosis via a SIRT3-SOD2-mitochondrial reactive oxygen species pathway
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Diversity of Pyrrolizidine Alkaloids in the Boraginaceae Structures, Distribution, and Biological Properties
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Pyrrolizidine Alkaloid Extraction and Analysis: Recent Updates
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Untargeted Metabolomic Profiling and Bioactivity Insights into Alkanna corcyrensis
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Pyrrolizidine Alkaloid-Induced Hepatotoxicity Associated with the Formation of Reactive Metabolite-Derived Pyrrole–Protein Adducts
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Analysis of Pyrrolizidine Alkaloids in Stingless Bee Honey and Identification of a Botanical Source as Ageratum conyzoides
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