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Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Nuclear Factor κB1/RelA Mediates Inflammation in Human Lung Epithelial Cells at Atmospheric Oxygen Levels
inferredcites →https://doi.org/10.1006/taap.1996.8075openalex-snapshot
Carcinogenicity Assessment of Selected Nickel Compounds
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Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms
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Vimentin, zeb1 and Sip1 are up-regulated in triple-negative and basal-like breast cancers: association with an aggressive tumour phenotype
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Snail Family Regulation and Epithelial Mesenchymal Transitions in Breast Cancer Progression
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Carcinogenic effect of nickel compounds
inferredcites →https://doi.org/10.1016/0165-7992(86)90056-4openalex-snapshot
Assessment of the uptake and mutagenicity of nickel chloride in Salmonella tester strains
inferredcites →https://doi.org/10.1016/j.cell.2009.11.007openalex-snapshot
Epithelial-Mesenchymal Transitions in Development and Disease
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Hallmarks of Cancer: The Next Generation
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Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity
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Prognostic significance of Zinc finger E-box binding homeobox 1 (ZEB1) expression in cancer cells and cancer-associated fibroblasts in pancreatic head cancer
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Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis
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Molecular mechanisms of nickel carcinogenesis
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Nickel essentiality, toxicity, and carcinogenicity
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Nickel subsulfide is genotoxic in vitro but shows no mutagenic potential in respiratory tract tissues of BigBlue™ rats and Muta™Mouse mice in vivo after inhalation
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Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium
inferredcites →https://doi.org/10.1038/ncb1722openalex-snapshot
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
inferredcites →https://doi.org/10.1038/nrc2131openalex-snapshot
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
inferredcites →https://doi.org/10.1038/nrc2627openalex-snapshot
Parallel progression of primary tumours and metastases
inferredcites →https://doi.org/10.1038/nrm3758openalex-snapshot
Molecular mechanisms of epithelial–mesenchymal transition
inferredcites →https://doi.org/10.1038/onc.2010.102openalex-snapshot
ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1
inferredcites →https://doi.org/10.1038/onc.2013.128openalex-snapshot
Multilayer control of the EMT master regulators
inferredcites →https://doi.org/10.1038/sj.onc.1203721openalex-snapshot
Evidence for a function of CtBP in epithelial gene regulation and anoikis
inferredcites →https://doi.org/10.1039/b209623bopenalex-snapshot
Radiographic evidence of pulmonary fibrosis and possible etiologic factors at a nickel refinery in Norway
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Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells
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In vivo aging of orthodontic alloys: implications for corrosion potential, nickel release, and biocompatibility.
inferredcites →https://doi.org/10.1053/ajcd.1994.3246openalex-snapshot
Health Problems Associated With Nickel Refining and Use
inferredcites →https://doi.org/10.1055/s-2006-957332openalex-snapshot
Epithelial-Mesenchymal Interactions in Pulmonary Fibrosis
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Effects of cigarette smoke on the human airway epithelial cell transcriptome
inferredcites →https://doi.org/10.1073/pnas.1318192110openalex-snapshot
MicroRNA-based regulation of epithelial–hybrid–mesenchymal fate determination
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Epigenetic dysregulation by nickel through repressive chromatin domain disruption
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Functional Cooperation between Snail1 and Twist in the Regulation of ZEB1 Expression during Epithelial to Mesenchymal Transition
inferredcites →https://doi.org/10.1074/jbc.m111.291195openalex-snapshot
Nickel-induced Epithelial-Mesenchymal Transition by Reactive Oxygen Species Generation and E-cadherin Promoter Hypermethylation
inferredcites →https://doi.org/10.1074/jbc.m403057200openalex-snapshot
Depletion of Intracellular Ascorbate by the Carcinogenic Metals Nickel and Cobalt Results in the Induction of Hypoxic Stress
inferredcites →https://doi.org/10.1080/15384101.2015.1006048openalex-snapshot
ZEB1: At the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance
inferredcites →https://doi.org/10.1083/jcb.200601018openalex-snapshot
The epithelial–mesenchymal transition: new insights in signaling, development, and disease
inferredcites →https://doi.org/10.1089/ees.2004.21.691openalex-snapshot
Removal of Nickel and Phenanthrene from Kaolin Soil Using Different Extractants
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Exposure to Different Forms of Nickel and Risk of Lung Cancer
inferredcites →https://doi.org/10.1093/annhyg/38.2.189openalex-snapshot
HEALTH PROBLEMS ASSOCIATED WITH NICKEL REFINING AND USE *
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Open source clustering software
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Java Treeview—extensible visualization of microarray data
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Causal analysis approaches in Ingenuity Pathway Analysis
inferredcites →https://doi.org/10.1093/carcin/bgl004openalex-snapshot
Alterations of histone modifications and transgene silencing by nickel chloride
inferredcites →https://doi.org/10.1093/carcin/bgx038openalex-snapshot
Nickel induces transcriptional down-regulation of DNA repair pathways in tumorigenic and non-tumorigenic lung cells
inferredcites →https://doi.org/10.1093/nar/gkv468openalex-snapshot
ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap
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Epithelial–mesenchymal transition in the pathophysiology of airway remodelling in asthma
inferredcites →https://doi.org/10.1101/gad.219626.113openalex-snapshot
A double take on bivalent promoters
inferredcites →https://doi.org/10.1111/j.1749-6632.2003.tb05970.xopenalex-snapshot
Epigenetics and the Environment
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Cancer of the Lung and Nose in Nickel Workers
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A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition
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EMT and Stem Cell–Like Properties Associated with miR-205 and miR-200 Epigenetic Silencing Are Early Manifestations during Carcinogen-Induced Transformation of Human Lung Epithelial Cells
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The basics of epithelial-mesenchymal transition
inferredcites →https://doi.org/10.1172/jci76725openalex-snapshot
ZEB1 drives epithelial-to-mesenchymal transition in lung cancer
inferredcites →https://doi.org/10.1186/1471-2121-10-94openalex-snapshot
Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway
inferredcites →https://doi.org/10.1186/1755-1536-5-s1-s28openalex-snapshot
Reversal of transforming growth factor-β induced epithelial-to-mesenchymal transition and the ZEB proteins
inferredcites →https://doi.org/10.1186/gb-2007-8-9-r201openalex-snapshot
Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1186/s13059-015-0720-3openalex-snapshot
BioWardrobe: an integrated platform for analysis of epigenomics and transcriptomics data
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E-cadherin–integrin crosstalk in cancer invasion and metastasis
inferredcites →https://doi.org/10.1289/ehp.121-a298openalex-snapshot
Uncertain Inheritance: Transgenerational Effects of Environmental Exposures
inferredcites →https://doi.org/10.1289/ehp.8981221openalex-snapshot
The Accumulation of Nickel in Human Lungs
inferredcites →https://doi.org/10.1371/journal.pone.0031901openalex-snapshot
Transgenerational Actions of Environmental Compounds on Reproductive Disease and Identification of Epigenetic Biomarkers of Ancestral Exposures
inferredcites →https://doi.org/10.1371/journal.pone.0120824openalex-snapshot
Persistence of Smoking-Induced Dysregulation of MiRNA Expression in the Small Airway Epithelium Despite Smoking Cessation
inferredcites →https://doi.org/10.1515/reveh.2011.012openalex-snapshot
Exploring the molecular mechanisms of nickel-induced genotoxicity and carcinogenicity: a literature review
inferredcites →https://doi.org/10.2147/cmar.s38156openalex-snapshot
Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives
inferredcites →https://doi.org/10.3109/10408448909029327openalex-snapshot
Toxicity and Carcinogenicity of Nickel Compounds
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Transcriptional repression of E‐cadherin in nickel‐exposed lung epithelial cells mediated by loss of Sp1 binding at the promoter
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Emerging Materials and Environment: A Brief Introduction
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ZEB1: New advances in fibrosis and cancer
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A review on the potential risks and mechanisms of heavy metal exposure to Chronic Obstructive Pulmonary Disease
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2021.129996openalex-snapshot
Nickel in terrestrial biota: Comprehensive review on contamination, toxicity, tolerance and its remediation approaches
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Nickel (Ni) phytotoxicity and detoxification mechanisms: A review
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Exogenous hydrogen sulfide donor NaHS alleviates nickel-induced epithelial-mesenchymal transition and the migration of A549 cells by regulating TGF-β1/Smad2/Smad3 signaling
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Endoplasmic reticulum stress mediates nickel chloride-induced epithelial‑mesenchymal transition and migration of human lung cancer A549 cells through Smad2/3 and p38 MAPK activation
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2024.115954openalex-snapshot
DNMT3a-mediated upregulation of the stress inducible protein sestrin-2 contributes to malignant transformation of human bronchial epithelial cells following nickel exposure
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2025.118274openalex-snapshot
Association between nickel and multiple metabolic outcomes: The mediating roles of lipid metabolism and inflammation
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Biomonitoring of exposure to metals and metalloids using toenail and fingernail sampling in individuals from artisanal gold mining areas in Mali
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Epigenetic toxicity of heavy metals − implications for embryonic stem cells
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RETRACTED: Comprehensive review on toxic heavy metals in the aquatic system: sources, identification, treatment strategies, and health risk assessment
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Chronic nickel exposure alters extracellular vesicles to mediate cancer progression via sustained NUPR1 expression
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A novel triaminopyridine fluorescent probe based on AIE effect with high selectivity under solvent shielding effect
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Dysregulated bidirectional epithelial–mesenchymal crosstalk: A core determinant of lung fibrosis progression
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MiR-873-5p inhibits cell migration, invasion and epithelial-mesenchymal transition in colorectal cancer via targeting ZEB1
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Epithelial-mesenchymal transition promotes metabolic reprogramming to suppress ferroptosis
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Cadmium exposure upregulates SNAIL through miR-30 repression in human lung epithelial cells
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Nickel-induced alterations to chromatin structure and function
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Nickel-induced transcriptional memory in lung epithelial cells promotes interferon signaling upon nicotine exposure
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Nickel exposure disrupts epigenetic repression of developmental genes in mouse embryonic stem cells
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Nickel induced transcriptional changes persist post exposure through epigenetic reprograming
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Purification of Aqueous Solutions from Nickel Using Ceramic Waste
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