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ER stress and inflammation crosstalk in obesity

https://doi.org/10.1002/med.21921

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Prevalence of High Body Mass Index in US Children and Adolescents, 2007-2008

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Bax inhibitor‐1 protects from nonalcoholic steatohepatitis by limiting inositol‐requiring enzyme 1 alpha signaling in mice

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High cholesterol diet activates ER stress mediated apoptosis in testes tissue: Role of α‐tocopherol

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Endoplasmic reticulum stress and NF‐kB activation in SARS‐CoV ‐2 infected cells and their response to antiviral therapy

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NK cells induce hepatic ER stress to promote insulin resistance in obesity through osteopontin production

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Epigenetic modification in alcohol‐related liver diseases

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Human aquaporin‐11 is a water and glycerol channel and localizes in the vicinity of lipid droplets in human adipocytes

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Time-dependent cellular response in the liver and heart in a dietary-induced obese mouse model: the potential role of ER stress and autophagy

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Endurance exercise training ameliorates insulin resistance and reticulum stress in adipose and hepatic tissue in obese rats

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Regulation of energy metabolism by the skeleton: Osteocalcin and beyond

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“Sick Fat,” Metabolic Disease, and Atherosclerosis

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Mitophagy Receptors and Mediators: Therapeutic Targets in the Management of Cardiovascular Ageing

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Endoplasmic reticulum stress and protein quality control in diabetic cardiomyopathy

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ER stress-induced cell death mechanisms

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Pathologic endoplasmic reticulum stress induced by glucotoxic insults inhibits adipocyte differentiation and induces an inflammatory phenotype

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Enzyme-based autophagy in anti-neoplastic management: From molecular mechanisms to clinical therapeutics

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Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice

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Telmisartan attenuates obesity-induced insulin resistance via suppression of AMPK mediated ER stress

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Pharmacological targeting of endoplasmic reticulum stress signaling in cancer

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Dysregulation of iron metabolism in cardiovascular diseases: From iron deficiency to iron overload

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The role of tauroursodeoxycholic acid on adipogenesis of human adipose-derived stem cells by modulation of ER stress

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An insight into the medicinal attributes of berberine derivatives: A review

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Coordinated Regulation of Nutrient and Inflammatory Responses by STAMP2 Is Essential for Metabolic Homeostasis

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Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

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ER Stress Protein CHOP Mediates Insulin Resistance by Modulating Adipose Tissue Macrophage Polarity

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AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

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Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism

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Catestatin improves insulin sensitivity by attenuating endoplasmic reticulum stress: In vivo and in silico validation

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Berberine ameliorates obesity-induced chronic inflammation through suppression of ER stress and promotion of macrophage M2 polarization at least partly via downregulating lncRNA Gomafu

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Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3 inflammasome activation in adipose tissue

inferredcites →https://doi.org/10.1016/j.jhep.2016.02.004openalex-snapshot

IL-6 pathway in the liver: From physiopathology to therapy

inferredcites →https://doi.org/10.1016/j.jnutbio.2020.108342openalex-snapshot

Impact of caloric restriction on AMPK and endoplasmic reticulum stress in peripheral tissues and circulating peripheral blood mononuclear cells from Zucker rats

inferredcites →https://doi.org/10.1016/j.mce.2016.06.008openalex-snapshot

Metformin and resveratrol inhibit Drp1-mediated mitochondrial fission and prevent ER stress-associated NLRP3 inflammasome activation in the adipose tissue of diabetic mice

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Telmisartan improves insulin sensitivity in nondiabetic patients with essential hypertension

inferredcites →https://doi.org/10.1016/j.metabol.2016.06.004openalex-snapshot

Physical exercise alleviates ER stress in obese humans through reduction in the expression and release of GRP78 chaperone

inferredcites →https://doi.org/10.1016/j.metabol.2021.154840openalex-snapshot

FUNDC1 insufficiency sensitizes high fat diet intake-induced cardiac remodeling and contractile anomaly through ACSL4-mediated ferroptosis

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Moderate weight loss attenuates chronic endoplasmic reticulum stress and mitochondrial dysfunction in human obesity

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Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics

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Natural products targeting ER stress pathway for the treatment of cardiovascular diseases

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Melatonin-based therapeutics for atherosclerotic lesions and beyond: Focusing on macrophage mitophagy

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Sodium 4-phenylbutyrate protects against liver ischemia reperfusion injury by inhibition of endoplasmic reticulum-stress mediated apoptosis

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Ferritinophagy and ferroptosis in the management of metabolic diseases

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ER stress in obesity pathogenesis and management

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RETRACTED: Endoplasmic reticulum chaperon tauroursodeoxycholic acid alleviates obesity-induced myocardial contractile dysfunction

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Signal Transduction by the JNK Group of MAP Kinases

inferredcites →https://doi.org/10.1016/s0960-9822(00)00583-2openalex-snapshot

ER stress response: Getting the UPR hand on misfolded proteins

inferredcites →https://doi.org/10.1016/s0968-0004(00)01674-1openalex-snapshot

Mitochondria, oxygen free radicals, disease and ageing

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The FAD- and O2-Dependent Reaction Cycle of Ero1-Mediated Oxidative Protein Folding in the Endoplasmic Reticulum

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Compound K Enhances Insulin Secretion with Beneficial Metabolic Effects in db/db Mice

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Competition between glutathione and protein thiols for disulphide-bond formation

inferredcites →https://doi.org/10.1038/cddis.2011.132openalex-snapshot

ER stress activates the NLRP3 inflammasome via an UPR-independent pathway

inferredcites →https://doi.org/10.1038/cddis.2015.248openalex-snapshot

ER stress induces NLRP3 inflammasome activation and hepatocyte death

inferredcites →https://doi.org/10.1038/cr.2010.178openalex-snapshot

Crosstalk of reactive oxygen species and NF-κB signaling

inferredcites →https://doi.org/10.1038/emm.2006.71openalex-snapshot

Berberine reduces the expression of adipogenic enzymes and inflammatory molecules of 3T3-L1 adipocyte

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Inflammation and endoplasmic reticulum stress in obesity and diabetes

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Inflammation and metabolic disorders

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From endoplasmic-reticulum stress to the inflammatory response

inferredcites →https://doi.org/10.1038/ncomms11378openalex-snapshot

The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation

inferredcites →https://doi.org/10.1038/ni.3709openalex-snapshot

The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity

inferredcites →https://doi.org/10.1038/nm.2279openalex-snapshot

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

inferredcites →https://doi.org/10.1038/nm.3056openalex-snapshot

Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance

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Adapting to obesity with adipose tissue inflammation

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Signal integration in the endoplasmic reticulum unfolded protein response

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Chromium Alleviates Glucose Intolerance, Insulin Resistance, and Hepatic ER Stress in Obese Mice

inferredcites →https://doi.org/10.1038/oby.2010.200openalex-snapshot

FFA‐Induced Adipocyte Inflammation and Insulin Resistance: Involvement of ER Stress and IKKβ Pathways

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Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases

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The NLRP3 inflammasome: molecular activation and regulation to therapeutics

inferredcites →https://doi.org/10.1038/s41580-020-0250-zopenalex-snapshot

Mechanisms, regulation and functions of the unfolded protein response

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Pharmacological targeting of the unfolded protein response for disease intervention

inferredcites →https://doi.org/10.1038/s41598-021-94944-5openalex-snapshot

Exercise training mitigates ER stress and UCP2 deficiency-associated coronary vascular dysfunction in atherosclerosis

inferredcites →https://doi.org/10.1038/sj.onc.1210638openalex-snapshot

Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis

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Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue

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Caloric restriction of db/db mice reverts hepatic steatosis and body weight with divergent hepatic metabolism

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Auditory evoked potential could reflect emotional sensitivity and impulsivity

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Correction: Corrigendum: Changes in Central Asia’s Water Tower: Past, Present and Future

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The complex role of adipokines in obesity, inflammation, and autoimmunity

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Projected U.S. State-Level Prevalence of Adult Obesity and Severe Obesity

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PERK-dependent Activation of Nrf2 Contributes to Redox Homeostasis and Cell Survival following Endoplasmic Reticulum Stress

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Identification of Transcriptional Targets of HOXA5

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Signaling the Unfolded Protein Response from the Endoplasmic Reticulum

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Induction of Endoplasmic Reticulum Stress in Retinal Pericytes by Glucose Deprivation

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The anti-obesity effects of rhein on improving insulin resistance (IR) and blood lipid levels are involved in endoplasmic reticulum stress (ERs), inflammation, and oxidative stress in vivo and vitro

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Oxidative protein folding in eukaryotes

inferredcites →https://doi.org/10.1089/ars.2006.8.1391openalex-snapshot

The Endoplasmic Reticulum: Folding, Calcium Homeostasis, Signaling, and Redox Control

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Targeting autophagy in neurodegenerative diseases: From molecular mechanisms to clinical therapeutics

inferredcites →https://doi.org/10.1111/febs.13627openalex-snapshot

NFKB1: a suppressor of inflammation, ageing and cancer

inferredcites →https://doi.org/10.1111/imm.13002openalex-snapshot

Properties and functions of adipose tissue macrophages in obesity

inferredcites →https://doi.org/10.1111/jcmm.14600openalex-snapshot

Hoxa5 alleviates obesity‐induced chronic inflammation by reducing ER stress and promoting M2 macrophage polarization in mouse adipose tissue

inferredcites →https://doi.org/10.1111/jdi.13211openalex-snapshot

Nicotinic acetylcholine receptor signaling regulates inositol‐requiring enzyme 1α activation to protect β‐cells against terminal unfolded protein response under irremediable endoplasmic reticulum stress

inferredcites →https://doi.org/10.1126/sciadv.abc8561openalex-snapshot

FUNDC1 interacts with FBXL2 to govern mitochondrial integrity and cardiac function through an IP3R3-dependent manner in obesity

inferredcites →https://doi.org/10.1126/science.1128294openalex-snapshot

Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes

inferredcites →https://doi.org/10.1126/science.182.4108.166openalex-snapshot

Overeating and Obesity from Damage to a Noradrenergic System in the Brain

inferredcites →https://doi.org/10.1126/science.287.5453.664openalex-snapshot

Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1

inferredcites →https://doi.org/10.1126/science.aaa0079openalex-snapshot

S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction

inferredcites →https://doi.org/10.1128/mcb.23.20.7198-7209.2003openalex-snapshot

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

inferredcites →https://doi.org/10.1128/mcb.24.23.10161-10168.2004openalex-snapshot

Translational Repression Mediates Activation of Nuclear Factor Kappa B by Phosphorylated Translation Initiation Factor 2

inferredcites →https://doi.org/10.1128/mcb.26.8.3071-3084.2006openalex-snapshot

Autocrine Tumor Necrosis Factor Alpha Links Endoplasmic Reticulum Stress to the Membrane Death Receptor Pathway through IRE1α-Mediated NF-κB Activation and Down-Regulation of TRAF2 Expression

inferredcites →https://doi.org/10.1152/physrev.00030.2020openalex-snapshot

Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications

inferredcites →https://doi.org/10.1155/2012/374936openalex-snapshot

Rhein Reduces Fat Weight indb/dbMouse and Prevents Diet-Induced Obesity in C57Bl/6 Mouse through the Inhibition of PPARγSignaling

inferredcites →https://doi.org/10.1155/2015/578107openalex-snapshot

Rhein: A Review of Pharmacological Activities

inferredcites →https://doi.org/10.1161/circresaha.110.225698openalex-snapshot

Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

inferredcites →https://doi.org/10.1172/jci25102openalex-snapshot

Inflammation, stress, and diabetes

inferredcites →https://doi.org/10.1172/jci29881openalex-snapshot

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

inferredcites →https://doi.org/10.1177/1753425913508593openalex-snapshot

Endoplasmic reticulum stress is sufficient for the induction of IL-1β production via activation of the NF-κB and inflammasome pathways

inferredcites →https://doi.org/10.1194/jlr.m092510openalex-snapshot

High-saturated-fat diet-induced obesity causes hepatic interleukin-6 resistance via endoplasmic reticulum stress

inferredcites →https://doi.org/10.1194/jlr.m900216-jlr200openalex-snapshot

The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response

inferredcites →https://doi.org/10.1194/jlr.r700007-jlr200openalex-snapshot

Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease

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Chemical Chaperones: A Pharmacological Strategy for Disorders of Protein Folding and Trafficking

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Osteocalcin Reverses Endoplasmic Reticulum Stress and Improves Impaired Insulin Sensitivity Secondary to Diet-Induced Obesity Through Nuclear Factor-κB Signaling Pathway

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Bilirubin Increases Insulin Sensitivity in Leptin-Receptor Deficient and Diet-Induced Obese Mice Through Suppression of ER Stress and Chronic Inflammation

inferredcites →https://doi.org/10.1210/endrev/bnab006openalex-snapshot

ER Stress in Cardiometabolic Diseases: From Molecular Mechanisms to Therapeutics

inferredcites →https://doi.org/10.1371/journal.pone.0045078openalex-snapshot

ER Stress Activates NF-κB by Integrating Functions of Basal IKK Activity, IRE1 and PERK

inferredcites →https://doi.org/10.1371/journal.pone.0047493openalex-snapshot

Regulation of Insulin and Leptin Signaling by Muscle Suppressor of Cytokine Signaling 3 (SOCS3)

inferredcites →https://doi.org/10.1371/journal.pone.0078620openalex-snapshot

Differential Responses of Hepatic Endoplasmic Reticulum Stress and Inflammation in Diet-Induced Obese Rats with High-Fat Diet Rich in Lard Oil or Soybean Oil

inferredcites →https://doi.org/10.1371/journal.pone.0183541openalex-snapshot

Resveratrol and caloric restriction prevent hepatic steatosis by regulating SIRT1-autophagy pathway and alleviating endoplasmic reticulum stress in high-fat diet-fed rats

inferredcites →https://doi.org/10.15252/embr.202051679openalex-snapshot

EI24 promotes cell adaption to ER stress by coordinating IRE1 signaling and calcium homeostasis

inferredcites →https://doi.org/10.1684/ecn.2018.0415openalex-snapshot

Obesity and inflammation

inferredcites →https://doi.org/10.18632/oncotarget.6712openalex-snapshot

The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma

inferredcites →https://doi.org/10.2337/db10-0315openalex-snapshot

Antiobesity and Antihyperglycemic Effects of Ginsenoside Rb1 in Rats

inferredcites →https://doi.org/10.3389/fcell.2020.00147openalex-snapshot

Fibroblast Growth Factor 2 Attenuates Renal Ischemia-Reperfusion Injury via Inhibition of Endoplasmic Reticulum Stress

inferredcites →https://doi.org/10.3389/fimmu.2015.00637openalex-snapshot

The Macrophage Switch in Obesity Development

inferredcites →https://doi.org/10.3389/fimmu.2019.03147openalex-snapshot

Insights Into the Role of Endoplasmic Reticulum Stress in Infectious Diseases

inferredcites →https://doi.org/10.3389/fmolb.2019.00011openalex-snapshot

Structure and Molecular Mechanism of ER Stress Signaling by the Unfolded Protein Response Signal Activator IRE1

inferredcites →https://doi.org/10.3389/fphar.2018.01366openalex-snapshot

EGCG Reduces Obesity and White Adipose Tissue Gain Partly Through AMPK Activation in Mice

inferredcites →https://doi.org/10.3389/fphys.2019.00372openalex-snapshot

A Short-Term High-Fat Diet Alters Glutathione Levels and IL-6 Gene Expression in Oxidative Skeletal Muscles of Young Rats

inferredcites →https://doi.org/10.3390/cells8111436openalex-snapshot

Physical Exercise and Selective Autophagy: Benefit and Risk on Cardiovascular Health

inferredcites →https://doi.org/10.3390/cells9061403openalex-snapshot

Aquaporin-11 Contributes to TGF-β1-induced Endoplasmic Reticulum Stress in Human Visceral Adipocytes: Role in Obesity-Associated Inflammation

inferredcites →https://doi.org/10.3390/ijms19123805openalex-snapshot

Regulation of iNOS on Immune Cells and Its Role in Diseases

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New insights in bilirubin metabolism and their clinical implications

inferredcites →https://doi.org/10.3760/cma.j.cn112137-20210620-01393openalex-snapshot

[Effect of metformin combined with intermittent fasting on endoplasmic reticulum stress after cerebral ischemia-reperfusion in mice].

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Deciphering the Role of Autophagy in Heart Failure

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COVID-19-Induced Cardiovascular Damage Differs from other Prevalent Viruses

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Phyllanthus emblica L. Suppresses Methylglyoxal-Triggered Leptin Resistance in Peripheral Tissues of High-Fat Diet-Fed Rats

inferred← citeshttps://doi.org/10.1002/evj.70195openalex-snapshot

Protective effects of adiponectin receptor agonists against equine lamellar endoplasmic reticulum stress

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Synergistic Anti‐Obesity Effect of Akkermansia muciniphila AKM Lab‐01 and Garcinia cambogia Extract via Gut Microbiota Remodeling in Diet‐Induced Obese Mice

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Vitamin D and Dapagliflozin Alleviate Renal Injury and Insulin Resistance in a Diet‐Induced Metabolic Syndrome Rat Model

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Casein Kinase 2α Ablation Confers Protection Against Metabolic Dysfunction‐Associated Steatotic Liver Disease: Role of FUN14 Domain Containing 1‐Dependent Regulation of Mitophagy and Ferroptosis

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ROS: Pathogenesis and Progression in Obesity

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WFS1 Gene Mutation (c.2389G > A) Induces Immune Disorders by Promoting DC Maturation through Inhibition of TMEM176A

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New insights of DsbA-L in the pathogenesis of metabolic diseases

inferred← citeshttps://doi.org/10.1007/s11033-024-09334-7openalex-snapshot

Quercetin declines LPS induced inflammation and augments adiponectin expression in 3T3-L1 differentiated adipocytes SIRT-1 dependently

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LncRNA ZFAS1 Combined with SRSF1 Regulate CNPY2 Expression and Leads to Microglia Endoplasmic Reticulum Stress–Induced Spinal Cord Injury

inferred← citeshttps://doi.org/10.1007/s13105-026-01163-5openalex-snapshot

Exercise reverses high-fat diet-induced perivascular adipose tissue dysfunction through modulation of UCP2 and TXNIP/NLRP3 pathways

inferred← citeshttps://doi.org/10.1016/b978-0-443-32888-6.00019-0openalex-snapshot

Phytochemicals in suppressing cancer proliferation

inferred← citeshttps://doi.org/10.1016/j.abb.2025.110370openalex-snapshot

Irisin and liraglutide combination therapy mitigates myocardial reperfusion injury in obese rats: Role of endoplasmic reticulum stress and apoptosis

inferred← citeshttps://doi.org/10.1016/j.biocel.2025.106874openalex-snapshot

Melatonin alleviates endoplasmic reticulum stress and its mediated inflammation in adipocytes via the PER1/ATF6 signal

inferred← citeshttps://doi.org/10.1016/j.bioorg.2024.107423openalex-snapshot

A FRET-based multifunctional fluorescence probe for the simultaneous detection of sulfite and viscosity in living cells

inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118859openalex-snapshot

A comparative study of idarubicin and doxorubicin in a chemically-induced in vivo mouse model for hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1016/j.biopha.2026.119687openalex-snapshot

Hepatoprotective effects of the branched-chain fatty acids 12-methylmyristic and 13-methylmyristic against palmitate-induced lipotoxicity

inferred← citeshttps://doi.org/10.1016/j.cbi.2024.111104openalex-snapshot

Inhibition of ER stress using tauroursodeoxycholic acid rescues obesity-evoked cardiac remodeling and contractile anomalies through regulation of ferroptosis

inferred← citeshttps://doi.org/10.1016/j.cbi.2024.111292openalex-snapshot

Activation of protein kinase B rescues against thapsigargin-elicited cardiac dysfunction through regulation of NADPH oxidase and ferroptosis

inferred← citeshttps://doi.org/10.1016/j.cellsig.2025.111702openalex-snapshot

Unfolded protein response-activated NLRP3 inflammasome contributes to pyroptotic and apoptotic podocyte injury in diabetic kidney disease via the CHOP-TXNIP axis

inferred← citeshttps://doi.org/10.1016/j.compbiomed.2023.107816openalex-snapshot

Bioinformatics-driven discovery of silica nanoparticles induces apoptosis and renal damage via the unfolded protein response in NRK-52E cells and rat kidney

inferred← citeshttps://doi.org/10.1016/j.ebiom.2026.106290openalex-snapshot

Influence of obesity on susceptibility to systemic symptoms and host responses to orthoflaviviral infection: a prospective observational study using yellow fever vaccine to simulate acute infection

inferred← citeshttps://doi.org/10.1016/j.ejphar.2025.177509openalex-snapshot

Pharmacological landscape of endoplasmic reticulum stress: Uncovering therapeutic avenues for metabolic diseases

inferred← citeshttps://doi.org/10.1016/j.envint.2024.108445openalex-snapshot

Methylparaben induces hepatic glycolipid metabolism disorder by activating the IRE1α-XBP1 signaling pathway in male mice

inferred← citeshttps://doi.org/10.1016/j.fbio.2025.107319openalex-snapshot

Impact of C-8 hydroxylation and C-7 methylglucosylation of dihydroquercetin on glucose metabolism in diabetic zebrafish larvae

inferred← citeshttps://doi.org/10.1016/j.fct.2023.113736openalex-snapshot

Chloroacetonitrile exposure induces endoplasmic reticulum stress and affects spindle assembly in mouse oocytes

inferred← citeshttps://doi.org/10.1016/j.foodres.2025.115940openalex-snapshot

Hydroxylation of dihydromyricetin via Beauveria bassiana fermentation enhances its efficacy in improving insulin signaling: Insights into inflammation, oxidative stress, and endoplasmic reticulum stress

inferred← citeshttps://doi.org/10.1016/j.identj.2026.109472openalex-snapshot

Obesity as a Determinant of Periodontal Therapy Outcomes: Insights on Oxidative and Endoplasmic Reticulum Stress Pathways

inferred← citeshttps://doi.org/10.1016/j.intimp.2025.115968openalex-snapshot

Endoplasmic reticulum stress orchestrates cGAS–STING activation in lipid metabolism–associated disorders

inferred← citeshttps://doi.org/10.1016/j.isci.2023.107956openalex-snapshot

EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway

inferred← citeshttps://doi.org/10.1016/j.jare.2025.01.012openalex-snapshot

Reductive stress: The key pathway in metabolic disorders induced by overnutrition

inferred← citeshttps://doi.org/10.1016/j.jep.2026.121890openalex-snapshot

Combination of Cornus officinalis Siebold and Moutan officinalis (L.) Lindl. alleviates the metabolic disorders of MAFLD through regulating IRE1α/ASK1/JNK pathway mediated endoplasmic reticulum stress

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.136873openalex-snapshot

Reticulophagy promotes EMT-induced fibrosis in offspring’s lung tissue after maternal exposure to carbon black nanoparticles during gestation by a m5C-dependent manner

inferred← citeshttps://doi.org/10.1016/j.jpha.2025.101318openalex-snapshot

Unlocking the potential of atractylenolide II: Mitigating non-alcoholic fatty liver disease through farnesoid X receptor-endoplasmic reticulum stress interplay

inferred← citeshttps://doi.org/10.1016/j.lfs.2022.121136openalex-snapshot

Comparison between aerobic exercise training and enalapril treatment as tools to improve diet-induced metabolic-associated fatty liver disease: Effects on endoplasmic reticulum stress markers

inferred← citeshttps://doi.org/10.1016/j.lfs.2023.121705openalex-snapshot

Cellular battle against endoplasmic reticulum stress and its adverse effect on health

inferred← citeshttps://doi.org/10.1016/j.lfs.2023.122229openalex-snapshot

Gut microbiota-mediated IL-22 alleviates metabolic inflammation

inferred← citeshttps://doi.org/10.1016/j.lfs.2025.123591openalex-snapshot

Akt mitigates ER stress-instigated cardiac dysfunction via regulation of ferroptosis and mitochondrial integrity in a DHODH-dependent manner

inferred← citeshttps://doi.org/10.1016/j.metabol.2022.155351openalex-snapshot

SUMOylation of ERp44 enhances Ero1α ER retention contributing to the pathogenesis of obesity and insulin resistance

inferred← citeshttps://doi.org/10.1016/j.metop.2023.100267openalex-snapshot

Drug targets regulate systemic metabolism and provide new horizons to treat nonalcoholic steatohepatitis

inferred← citeshttps://doi.org/10.1016/j.microc.2026.119223openalex-snapshot

Old trees, new blossoms: Leveraging a crizotinib-based activatable theranostic probe in cancer immunogenic cell death therapy

inferred← citeshttps://doi.org/10.1016/j.obmed.2025.100634openalex-snapshot

The UPR-oxidative stress nexus in diabetes and obesity: Exploring innovative therapeutic approaches for metabolic control

inferred← citeshttps://doi.org/10.1016/j.orcp.2025.02.011openalex-snapshot

Persian Gulf brown seaweed extracts showing anti-obesity potency on adipogenic differentiation in human adipose-derived mesenchymal stem cells and obese male rats

inferred← citeshttps://doi.org/10.1016/j.phymed.2024.156017openalex-snapshot

Zhimu-Huangbai herb-pair ameliorates hepatic steatosis in mice by regulating IRE1α/XBP1s pathway to inhibit SREBP-1c

inferred← citeshttps://doi.org/10.1016/j.saa.2026.127471openalex-snapshot

An endoplasmic reticulum-targeting NIR fluorescent probe for viscosity imaging in vitro and vivo

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2023.168649openalex-snapshot

Adverse impacts of environmentally relevant PFOS alternatives on mice pancreatic tissues

inferred← citeshttps://doi.org/10.1016/j.snb.2025.138803openalex-snapshot

An endoplasmic reticulum-targeted fluorescent probe for detecting polarity and viscosity and its bioimaging in vitro and vivo

inferred← citeshttps://doi.org/10.1016/j.taap.2025.117314openalex-snapshot

Melatonin ameliorates PM2.5-induced airway inflammation and apoptosis by PERK/eIF2α/ATF4/CHOP in chronic obstructive pulmonary disease mice

inferred← citeshttps://doi.org/10.1016/j.trsl.2024.02.002openalex-snapshot

Ntsr1 contributes to pulmonary hypertension by enhancing endoplasmic reticulum stress via JAK2-STAT3-Thbs1 signaling

inferred← citeshttps://doi.org/10.1016/j.yexcr.2025.114463openalex-snapshot

Endoplasmic reticulum stress and unfolded protein response in renal lipid metabolism

inferred← citeshttps://doi.org/10.1021/acs.jafc.5c00109openalex-snapshot

Microbial Fermentation-Derived Dihydroquercetin Derivatives Exhibit Superior Efficacy in Ameliorating Insulin Resistance via JNK/PI3K/AKT Pathway Regulation Compared to Dihydroquercetin

inferred← citeshttps://doi.org/10.1021/acsnano.6c09366openalex-snapshot

Lymph Node-Targeting Nanotherapy Combined with Photothermal Therapy to Potentiate Chimeric Antigen Receptor-T Cell Treatment of Oral Cancer

inferred← citeshttps://doi.org/10.1021/acsomega.6c00395openalex-snapshot

Islet Proteome Remodeling and Proteostasis Disruption in HFSC-Fed Mice

inferred← citeshttps://doi.org/10.1038/s41418-025-01483-xopenalex-snapshot

NAT10-mediated N4-acetylcytidine modification in KLF9 mRNA promotes adipogenesis

inferred← citeshttps://doi.org/10.1038/s41598-024-73659-3openalex-snapshot

Association of systemic immune-inflammation index with body mass index, waist circumference and prevalence of obesity in US adults

inferred← citeshttps://doi.org/10.1038/s41598-026-38099-1openalex-snapshot

Pharmacological investigation of bergapten isolated from Glehnia littoralis against periodontitis

inferred← citeshttps://doi.org/10.1038/s41598-026-43311-3openalex-snapshot

Integrated multi-omics analysis identifies and validates endoplasmic reticulum stress and mitophagy-related biomarkers in MASLD

inferred← citeshttps://doi.org/10.1039/d4ra05603eopenalex-snapshot

Efficient light-induced reactive oxygen species production from a far-red ER-targeting BODIPY dye

inferred← citeshttps://doi.org/10.1101/2025.03.14.643356openalex-snapshot

A comparative study of the chemotoxic effects of idarubicin and doxorubicin in a chemically-induced in vivo mouse model and in vitro models for hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1111/cns.70049openalex-snapshot

Inhibiting endoplasmic reticulum stress alleviates perioperative neurocognitive disorders by reducing neuroinflammation mediated by NLRP3 inflammasome activation

inferred← citeshttps://doi.org/10.1111/jnc.70490openalex-snapshot

Targeting Neuroinflammation in Depression: The Integrative Role of Sigma‐1 Receptor Modulation

inferred← citeshttps://doi.org/10.1111/nmo.14780openalex-snapshot

Endoplasmic reticulum stress: A possible connection between intestinal inflammation and neurodegenerative disorders

inferred← citeshttps://doi.org/10.1155/ijcp/8716019openalex-snapshot

Genetic Links Between Diet, Circulating Proteins, and Oral Lichen Planus: A Multicohort Mendelian Randomization and Mediation Analysis

inferred← citeshttps://doi.org/10.1167/iovs.66.5.12openalex-snapshot

Endoplasmic Reticulum Stress Drives Neuroinflammation Through Lipocalin 2 Upregulation in Retinal Microglia After Optic Nerve Injury

inferred← citeshttps://doi.org/10.1177/20420188241282707openalex-snapshot

Excessive or sustained endoplasmic reticulum stress: one of the culprits of adipocyte dysfunction in obesity

inferred← citeshttps://doi.org/10.1186/s12929-024-01054-1openalex-snapshot

The double whammy of ER-retention and dominant-negative effects in numerous autosomal dominant diseases: significance in disease mechanisms and therapy

inferred← citeshttps://doi.org/10.1186/s12951-025-03973-zopenalex-snapshot

β-Carotene liposome-based responsive hydrogel inhibits palmitoylation to restore intracellular calcium homeostasis for effective periodontitis treatment

inferred← citeshttps://doi.org/10.1186/s12964-023-01297-9openalex-snapshot

Identification of novel SCD1 inhibitor alleviates nonalcoholic fatty liver disease: critical role of liver-adipose axis

inferred← citeshttps://doi.org/10.1186/s12967-025-07558-0openalex-snapshot

CEBPD-mediated SGPP2 upregulation via PERK/ER stress in endothelial cells disrupts S1P homeostasis and impairs angiogenesis in chronic endometritis

inferred← citeshttps://doi.org/10.1186/s13048-025-01841-wopenalex-snapshot

Connection between granulosa cell pyroptosis and oocyte endoplasmic reticulum stress in a mouse model of polycystic ovary syndrome

inferred← citeshttps://doi.org/10.14514/beykozad.1568673openalex-snapshot

15-18 YAŞ ARALIĞINDAKI LISE ÖĞRENCILERI ARASINDA OBEZITE FARKINDALIĞI VE BESLENME DÜZENI

inferred← citeshttps://doi.org/10.1538/expanim.24-0027openalex-snapshot

Daphnetin ameliorates diabetic cardiomyopathy by regulating inflammation and endoplasmic reticulum stress-induced apoptosis

inferred← citeshttps://doi.org/10.18632/aging.205784openalex-snapshot

Unraveling the unfolded protein response signature: implications for tumor immune microenvironment heterogeneity and clinical prognosis in stomach cancer

inferred← citeshttps://doi.org/10.2174/0118715303319434241113161606openalex-snapshot

Berberine Improves Glucose and Lipid Metabolism in Obese Mice Through the Reduction of IRE1/GSK-3β Axis-Mediated Inflammation

inferred← citeshttps://doi.org/10.3350/cmh.2025.0559openalex-snapshot

RAB25/GCN1 signaling promotes endoplasmic reticulum stress to mediate alcohol-associated liver disease progression

inferred← citeshttps://doi.org/10.3389/fendo.2023.1124405openalex-snapshot

Roles of endoplasmic reticulum stress in the pathophysiology of polycystic ovary syndrome

inferred← citeshttps://doi.org/10.3389/fendo.2025.1592683openalex-snapshot

Adipose tissue dysfunction disrupts metabolic homeostasis: mechanisms linking fat dysregulation to disease

inferred← citeshttps://doi.org/10.3389/fimmu.2024.1381227openalex-snapshot

Endoplasmic reticulum stress: bridging inflammation and obesity-associated adipose tissue

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1889437openalex-snapshot

Obesity-driven low-grade chronic inflammation as a mechanistic bridge to chronic pain: from adipose tissue remodeling to central sensitization

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1961059openalex-snapshot

Obesity-associated inflammation and cancer: molecular mechanisms, evidence gaps, and therapeutic opportunities

inferred← citeshttps://doi.org/10.3389/fmolb.2024.1504015openalex-snapshot

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

inferred← citeshttps://doi.org/10.3389/fphar.2024.1446725openalex-snapshot

Therapeutic potential of arginine deprivation therapy for gliomas: a systematic review of the existing literature

inferred← citeshttps://doi.org/10.3390/ani15101384openalex-snapshot

Medium-Chain Fatty Acids Extracted from Black Soldier Fly (Hermetia illucens) Larvae Prevents High-Fat Diet-Induced Obesity In Vivo in C57BL/6J Mice

inferred← citeshttps://doi.org/10.3390/ani15111536openalex-snapshot

Effects of Grape By-Products on Oxidative Stress and Inflammation in Farm Animals: An Overview of Studies Performed in Pigs, Chickens, and Cattle

inferred← citeshttps://doi.org/10.3390/biom13071050openalex-snapshot

ER Stress, the Unfolded Protein Response and Osteoclastogenesis: A Review

inferred← citeshttps://doi.org/10.3390/ijms25074059openalex-snapshot

D-Allulose Reduces Hypertrophy and Endoplasmic Reticulum Stress Induced by Palmitic Acid in Murine 3T3-L1 Adipocytes

inferred← citeshttps://doi.org/10.3390/nu16244377openalex-snapshot

Folic Acid Prevents High-Fat Diet-Induced Postpartum Weight Retention in Rats, Which Is Associated with a Reduction in Endoplasmic Reticulum Stress-Mediated Hepatic Lipogenesis

inferred← citeshttps://doi.org/10.34133/research.1261openalex-snapshot

The Multiscale Heterogeneity of Adipose Tissue in Health and Disease

inferred← citeshttps://doi.org/10.37349/edd.2025.100583openalex-snapshot

Cholesterol and the gut-liver axis: unraveling their role in the onset and progression of metabolic-associated steatotic liver disease

inferred← citeshttps://doi.org/10.38212/2224-6614.3494openalex-snapshot

Effect of Indian gooseberry extract on improving methylglyoxal-associated leptin resistance in peripheral tissues of high-fat diet-fed rats

inferred← citeshttps://doi.org/10.3892/ijmm.2024.5385openalex-snapshot

Obesity and lipid metabolism in the development of osteoporosis (Review)

inferred← citeshttps://doi.org/10.3892/mmr.2024.13323openalex-snapshot

Role of bariatric surgery in improving diabetic cardiomyopathy: Molecular mechanisms and therapeutic perspectives (Review)

inferred← citeshttps://doi.org/10.4093/dmj.2024.0441openalex-snapshot

Serpina3c Mitigates Adipose Tissue Inflammation by Inhibiting the HIF1α-Mediated Endoplasmic Reticulum Overoxidation in Adipocytes

inferred← citeshttps://doi.org/10.7717/peerj.19192openalex-snapshot

The role of endoplasmic reticulum stress in type 2 diabetes mellitus mechanisms and impact on islet function

inferred← citeshttps://doi.org/10.7759/cureus.91155openalex-snapshot

Research Hotspots and Trends of Endoplasmic Reticulum Stress in Obesity From 2014 to 2024: A CiteSpace Visualization Analysis

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.