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Cerebral metabolic rate of oxygen (CMRO 2 ) mapping with hyperventilation challenge using quantitative susceptibility mapping (QSM)

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Impact of intravascular signal on quantitative measures of cerebral oxygen extraction and blood volume under normo‐ and hypercapnic conditions using an asymmetric spin echo approach
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Quantitative BOLD: Mapping of human cerebral deoxygenated blood volume and oxygen extraction fraction: Default state
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Measurement of brain perfusion, blood volume, and blood‐brain barrier permeability, using dynamic contrast‐enhanced T1‐weighted MRI at 3 tesla
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Quantitative susceptibility map reconstruction from MR phase data using bayesian regularization: Validation and application to brain imaging
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Morphology enabled dipole inversion (MEDI) from a single‐angle acquisition: Comparison with COSMOS in human brain imaging
inferredcites →https://doi.org/10.1002/mrm.22946openalex-snapshot
QUantitative Imaging of eXtraction of oxygen and TIssue consumption (QUIXOTIC) using venular‐targeted velocity‐selective spin labeling
inferredcites →https://doi.org/10.1002/mrm.23034openalex-snapshot
Accuracy of the cylinder approximation for susceptometric measurement of intravascular oxygen saturation
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Phase‐based regional oxygen metabolism (PROM) using MRI
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Investigating the magnetic susceptibility properties of fresh human blood for noninvasive oxygen saturation quantification
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Reducing the object orientation dependence of susceptibility effects in gradient echo MRI through quantitative susceptibility mapping
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Nonlinear formulation of the magnetic field to source relationship for robust quantitative susceptibility mapping
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Optimization strategies for evaluation of brain hemodynamic parameters with qBOLD technique
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Quantitative oxygenation venography from MRI phase
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Flow compensated quantitative susceptibility mapping for venous oxygenation imaging
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Recommended implementation of arterial spin‐labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia
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Comparison of MRI methods for measuring whole‐brain venous oxygen saturation
inferredcites →https://doi.org/10.1002/mrm.25358openalex-snapshot
Quantitative susceptibility mapping (QSM): Decoding MRI data for a tissue magnetic biomarker
inferredcites →https://doi.org/10.1002/mrm.25463openalex-snapshot
Quantitative mapping of cerebral metabolic rate of oxygen (CMRO2) using quantitative susceptibility mapping (QSM)
inferredcites →https://doi.org/10.1002/mrm.25610openalex-snapshot
Separation of cellular and BOLD contributions to T2* signal relaxation
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A novel background field removal method for MRI using projection onto dipole fields (PDF)
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New Robust 3-D Phase Unwrapping Algorithms: Application to Magnetic Field Mapping and Undistorting Echoplanar Images
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Hemoglobin: Structure, function, evolution, and pathology
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Time-Resolved MRI Oximetry for Quantifying CMRO2 and Vascular Reactivity
inferredcites →https://doi.org/10.1016/j.neuroimage.2005.09.057openalex-snapshot
Noninvasive quantification of cerebral blood volume in humans during functional activation
inferredcites →https://doi.org/10.1016/j.neuroimage.2007.10.049openalex-snapshot
Caffeine-induced uncoupling of cerebral blood flow and oxygen metabolism: A calibrated BOLD fMRI study
inferredcites →https://doi.org/10.1016/j.neuroimage.2011.08.082openalex-snapshot
Morphology enabled dipole inversion for quantitative susceptibility mapping using structural consistency between the magnitude image and the susceptibility map
inferredcites →https://doi.org/10.1016/j.neuroimage.2011.10.046openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.neuroimage.2011.12.017openalex-snapshot
Quantitative measurement of cerebral physiology using respiratory-calibrated MRI
inferredcites →https://doi.org/10.1016/j.neuroimage.2011.12.056openalex-snapshot
Magnetic resonance imaging of resting OEF and CMRO2 using a generalized calibration model for hypercapnia and hyperoxia
inferredcites →https://doi.org/10.1016/j.neuroimage.2012.02.022openalex-snapshot
Calibrated fMRI
inferredcites →https://doi.org/10.1016/j.neuroimage.2013.06.008openalex-snapshot
Measurement of OEF and absolute CMRO2: MRI-based methods using interleaved and combined hypercapnia and hyperoxia
inferredcites →https://doi.org/10.1016/j.neuroimage.2013.09.019openalex-snapshot
Detecting resting-state brain activity by spontaneous cerebral blood volume fluctuations using whole brain vascular space occupancy imaging
inferredcites →https://doi.org/10.1016/j.neuroimage.2015.10.083openalex-snapshot
Brain region and activity-dependent properties of M for calibrated fMRI
inferredcites →https://doi.org/10.1016/s1053-8119(02)91132-8openalex-snapshot
Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images
inferredcites →https://doi.org/10.1016/s1361-8415(01)00036-6openalex-snapshot
A global optimisation method for robust affine registration of brain images
inferredcites →https://doi.org/10.1038/jcbfm.1985.27openalex-snapshot
Regional Cerebral Blood Volume and Hematocrit Measured in Normal Human Volunteers by Single-Photon Emission Computed Tomography
inferredcites →https://doi.org/10.1038/jcbfm.2010.153openalex-snapshot
The Influence of Carbon Dioxide on Brain Activity and Metabolism in Conscious Humans
inferredcites →https://doi.org/10.1038/jcbfm.2010.42openalex-snapshot
Global Cerebral Oxidative Metabolism during Hypercapnia and Hypocapnia in Humans: Implications for BOLD fMRI
inferredcites →https://doi.org/10.1038/jcbfm.2010.49openalex-snapshot
MRI Estimation of Global Brain Oxygen Consumption Rate
inferredcites →https://doi.org/10.1038/jcbfm.2012.93openalex-snapshot
Effect of Hypoxia and Hyperoxia on Cerebral Blood Flow, Blood Oxygenation, and Oxidative Metabolism
inferredcites →https://doi.org/10.1038/jcbfm.2013.110openalex-snapshot
High Temporal Resolution MRI Quantification of Global Cerebral Metabolic Rate of Oxygen Consumption in Response to Apneic Challenge
inferredcites →https://doi.org/10.1038/jcbfm.2015.96openalex-snapshot
Method for Rapid MRI Quantification of Global Cerebral Metabolic Rate of Oxygen
inferredcites →https://doi.org/10.1038/sj.jcbfm.9600076openalex-snapshot
Changes in the Arterial Fraction of Human Cerebral Blood Volume during Hypercapnia and Hypocapnia Measured by Positron Emission Tomography
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Hematology: Basic Principles and Practice
inferredcites →https://doi.org/10.1063/1.1670155openalex-snapshot
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inferredcites →https://doi.org/10.1073/pnas.22.4.210openalex-snapshot
The Magnetic Properties and Structure of Hemoglobin, Oxyhemoglobin and Carbonmonoxyhemoglobin
inferredcites →https://doi.org/10.1073/pnas.81.17.5417openalex-snapshot
Magnetic susceptibility of oxy- and carbonmonoxyhemoglobins.
inferredcites →https://doi.org/10.1073/pnas.82.1.102openalex-snapshot
Reexamination of the evidence for paramagnetism in oxy- and carbonmonoxyhemoglobins.
inferredcites →https://doi.org/10.1073/pnas.87.24.9868openalex-snapshot
Brain magnetic resonance imaging with contrast dependent on blood oxygenation.
inferredcites →https://doi.org/10.1093/brain/113.1.27openalex-snapshot
CEREBRAL BLOOD FLOW, BLOOD VOLUME AND OXYGEN UTILIZATION
inferredcites →https://doi.org/10.1093/brain/awf047openalex-snapshot
Variability of cerebral blood volume and oxygen extraction: stages of cerebral haemodynamic impairment revisited
inferredcites →https://doi.org/10.1109/42.906424openalex-snapshot
Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm
inferredcites →https://doi.org/10.1109/tmi.2009.2023787openalex-snapshot
Nonlinear Regularization for Per Voxel Estimation of Magnetic Susceptibility Distributions From MRI Field Maps
inferredcites →https://doi.org/10.1137/0916069openalex-snapshot
A Limited Memory Algorithm for Bound Constrained Optimization
inferredcites →https://doi.org/10.1137/1034115openalex-snapshot
Analysis of Discrete Ill-Posed Problems by Means of the L-Curve
inferredcites →https://doi.org/10.1161/01.str.5.5.630openalex-snapshot
The Effects of Changes in Pa CO 2 Cerebral Blood Volume, Blood Flow, and Vascular Mean Transit Time
inferredcites →https://doi.org/10.1161/strokeaha.112.663716openalex-snapshot
Cerebrovascular Reserve and Stroke Risk in Patients With Carotid Stenosis or Occlusion
inferredcites →https://doi.org/10.1161/strokeaha.114.008154openalex-snapshot
Defining the Ischemic Penumbra Using Magnetic Resonance Oxygen Metabolic Index
inferredcites →https://doi.org/10.1172/jci101680openalex-snapshot
THE EFFECTS OF ACTIVE AND PASSIVE HYPERVENTILATION ON CEREBRAL BLOOD FLOW, CEREBRAL OXYGEN CONSUMPTION, CARDIAC OUTPUT, AND BLOOD PRESSURE OF NORMAL YOUNG MEN 1
inferredcites →https://doi.org/10.3171/jns.2002.96.1.0103openalex-snapshot
Regional cerebrovascular and metabolic effects of hyperventilation after severe traumatic brain injury
inferredcites →https://doi.org/10.3174/ajnr.a1538openalex-snapshot
The Acetazolamide Challenge: Techniques and Applications in the Evaluation of Chronic Cerebral Ischemia
inferredcites →https://doi.org/10.3174/ajnr.a3668openalex-snapshot
Oxygen Extraction Fraction and Stroke Risk in Patients with Carotid Stenosis or Occlusion: A Systematic Review and Meta-Analysis

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4190247openalex-extracted
The Clinical Applications of Oxygen Extraction Fraction (OEF) Metrics: A Systematic Review
inferred← citeshttps://doi.org/10.1002/brb3.3473openalex-snapshot
Interscanner reproducibility of volumetric quantitative susceptibility mapping about cerebral subcortical gray nuclei at different MR vendors with the same magnetic strength
inferred← citeshttps://doi.org/10.1002/jmri.25693openalex-snapshot
Clinical quantitative susceptibility mapping (QSM): Biometal imaging and its emerging roles in patient care
inferred← citeshttps://doi.org/10.1002/mp.17173openalex-snapshot
Unveiling metabolic patterns in dementia: Insights from high‐resolution quantitative blood‐oxygenation‐level‐dependent MRI
inferred← citeshttps://doi.org/10.1002/mrm.26657openalex-snapshot
Quantitative susceptibility mapping‐based cerebral metabolic rate of oxygen mapping with minimum local variance
inferred← citeshttps://doi.org/10.1002/mrm.26808openalex-snapshot
Cardiac quantitative susceptibility mapping (QSM) for heart chamber oxygenation
inferred← citeshttps://doi.org/10.1002/mrm.26952openalex-snapshot
Reproducibility of CMRO2 determination using dynamic 17O MRI
inferred← citeshttps://doi.org/10.1002/mrm.27078openalex-snapshot
Dynamic measurement of oxygen extraction fraction using a multiecho asymmetric spin echo (MASE) pulse sequence
inferred← citeshttps://doi.org/10.1002/mrm.27135openalex-snapshot
Cerebral metabolic rate of oxygen (CMRO2) mapping by combining quantitative susceptibility mapping (QSM) and quantitative blood oxygenation level‐dependent imaging (qBOLD)
inferred← citeshttps://doi.org/10.1002/mrm.27804openalex-snapshot
Comparison of gradient echo and gradient echo sampling of spin echo sequence for the quantification of the oxygen extraction fraction from a combined quantitative susceptibility mapping and quantitative BOLD (QSM+qBOLD) approach
inferred← citeshttps://doi.org/10.1002/mrm.27882openalex-snapshot
Using an artificial neural network for fast mapping of the oxygen extraction fraction with combined QSM and quantitative BOLD
inferred← citeshttps://doi.org/10.1002/mrm.27907openalex-snapshot
Cerebral OEF quantification: A comparison study between quantitative susceptibility mapping and dual‐gas calibrated BOLD imaging
inferred← citeshttps://doi.org/10.1002/mrm.27967openalex-snapshot
Cluster analysis of time evolution (CAT) for quantitative susceptibility mapping (QSM) and quantitative blood oxygen level‐dependent magnitude (qBOLD)‐based oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO2) mapping
inferred← citeshttps://doi.org/10.1002/mrm.28005openalex-snapshot
A dual‐tuned 17O/1H head array for direct brain oximetry at 3 Tesla
inferred← citeshttps://doi.org/10.1002/mrm.28390openalex-snapshot
Quantification of brain oxygen extraction fraction using QSM and a hyperoxic challenge
inferred← citeshttps://doi.org/10.1002/mrm.28447openalex-snapshot
Cerebral oxygen extraction fraction: Comparison of dual‐gas challenge calibrated BOLD with CBF and challenge‐free gradient echo QSM+qBOLD
inferred← citeshttps://doi.org/10.1002/mrm.28459openalex-snapshot
Simultaneous QSM and metabolic imaging of the brain using SPICE: Further improvements in data acquisition and processing
inferred← citeshttps://doi.org/10.1002/mrm.28875openalex-snapshot
Temporal clustering, tissue composition, and total variation for mapping oxygen extraction fraction using QSM and quantitative BOLD
inferred← citeshttps://doi.org/10.1002/mrm.29057openalex-snapshot
QQ‐NET – using deep learning to solve quantitative susceptibility mapping and quantitative blood oxygen level dependent magnitude (QSM+qBOLD or QQ) based oxygen extraction fraction (OEF) mapping
inferred← citeshttps://doi.org/10.1002/mrm.29272openalex-snapshot
Cerebral oxygen extraction fraction MRI : Techniques and applications
inferred← citeshttps://doi.org/10.1002/mrm.29300openalex-snapshot
T2‐oximetry– based cerebral venous oxygenation mapping using Fourier‐transform –based velocity‐selective pulse trains
inferred← citeshttps://doi.org/10.1002/mrm.30637openalex-snapshot
Rapid measurement of major cortical and subcortical venous oxygenation using EPI ‐based T2 ‐relaxation‐under‐phase‐contrast
inferred← citeshttps://doi.org/10.1002/mrm.70242openalex-snapshot
Reproducibility of QQ ( QSM + qBOLD ) Oxygen Extraction Fraction ( OEF ) Mapping in the Brain at 3 and 1. 5 T
inferred← citeshttps://doi.org/10.1002/mrm.70524openalex-snapshot
A Generalized Approach to Solving Deep Learning‐Based Quantitative Susceptibility Mapping and Quantitative Blood Oxygen Level Dependent Magnitude ( QSM + qBOLD or QQ ) for Oxygen Extraction Fraction ( OEF ) Mapping Across Diverse Acquisition Schemes
inferred← citeshttps://doi.org/10.1007/978-981-19-3949-5_13-1openalex-snapshot
Biomarkers of Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1007/978-981-99-7557-0_13openalex-snapshot
Biomarkers of Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1007/s00723-021-01345-yopenalex-snapshot
Brain Oximetry and the Quest for Quantified Metabolic Rate: Applications Using MRI and Near-Infrared Spectroscopy
inferred← citeshttps://doi.org/10.1007/s10072-024-07362-6openalex-snapshot
Oxygen extraction fraction (OEF) values and applications in neurological diseases
inferred← citeshttps://doi.org/10.1007/s10334-017-0629-9openalex-snapshot
Diffusional kurtosis imaging (DKI) incorporation into an intravoxel incoherent motion (IVIM) MR model to measure cerebral hypoperfusion induced by hyperventilation challenge in healthy subjects
inferred← citeshttps://doi.org/10.1007/s10334-025-01229-3openalex-snapshot
Comparing repeatability metrics for quantitative susceptibility mapping in the head and neck
inferred← citeshttps://doi.org/10.1007/s43657-022-00081-yopenalex-snapshot
Measurement of Cerebral Oxygen Extraction Fraction Using Quantitative BOLD Approach: A Review
inferred← citeshttps://doi.org/10.1016/j.bbi.2026.106480openalex-snapshot
Multimodal imaging suggests potential immune-vascular contributions to altered regional brain perfusion and oxygen metabolism in Post-COVID-19 Syndrome
inferred← citeshttps://doi.org/10.1016/j.clinimag.2023.02.001openalex-snapshot
Cerebral oxygen extraction fraction declines with ventricular enlargement in patients with normal pressure hydrocephalus
inferred← citeshttps://doi.org/10.1016/j.heliyon.2025.e42521openalex-snapshot
Evaluation of parameters extracted from tissue residue functions in dynamic susceptibility contrast MRI: Healthy volunteers examined during normal breathing and spontaneous hyperventilation
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2018.03.018openalex-snapshot
BOLD signal physiology: Models and applications
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2018.03.043openalex-snapshot
Interleaved quantitative BOLD: Combining extravascular R2ʹ - and intravascular R2-measurements for estimation of deoxygenated blood volume and hemoglobin oxygen saturation
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2018.05.050openalex-snapshot
Functional MRI of brain physiology in aging and neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2018.06.036openalex-snapshot
Whole head quantitative susceptibility mapping using a least-norm direct dipole inversion method
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2022.118952openalex-snapshot
Whole-brain 3D mapping of oxygen metabolism using constrained quantitative BOLD
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2023.120189openalex-snapshot
Cerebral oxygen metabolism from MRI susceptibility
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2023.120381openalex-snapshot
Evaluation of whole-brain oxygen metabolism in Alzheimer's disease using QSM and quantitative BOLD
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2024.120903openalex-snapshot
Trajectories and sex differences of brain structure, oxygenation and perfusion functions in normal aging
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2025.121682openalex-snapshot
Partial volume correction for quantifying venous oxygen saturation levels using contrast-enhanced MRI
inferred← citeshttps://doi.org/10.1016/j.nic.2024.03.003openalex-snapshot
Advanced Brain Imaging in Central Nervous System Demyelinating Diseases
inferred← citeshttps://doi.org/10.1088/1361-6560/abe737openalex-snapshot
A non-invasive reference-based method for imaging the cerebral metabolic rate of oxygen by PET/MR: theory and error analysis
inferred← citeshttps://doi.org/10.1088/1361-6560/ae2380openalex-snapshot
Model-based spatiotemporal synthetic data generation framework and deep-learning reconstruction for real-time MRI oxygen extraction fraction mapping
inferred← citeshttps://doi.org/10.1101/2021.03.13.434266openalex-snapshot
Dissolved oxygen minimally affects magnetic susceptibility in biologically relevant conditions
inferred← citeshttps://doi.org/10.1109/tbme.2017.2749298openalex-snapshot
Quantitative Susceptibility Mapping (QSM) Algorithms: Mathematical Rationale and Computational Implementations
inferred← citeshttps://doi.org/10.1111/jon.12990openalex-snapshot
Brain oxygen extraction and neural tissue susceptibility are associated with cognitive impairment in older individuals
inferred← citeshttps://doi.org/10.1148/rg.210054openalex-snapshot
Quantitative Susceptibility Mapping: Basic Methods and Clinical Applications
inferred← citeshttps://doi.org/10.1155/2019/7174937openalex-snapshot
Quantitative Susceptibility Mapping of Magnetic Quadrupole Moments
inferred← citeshttps://doi.org/10.1177/0271678x19867276openalex-snapshot
Calibrated fMRI for dynamic mapping of CMRO 2 responses using MR-based measurements of whole-brain venous oxygen saturation
inferred← citeshttps://doi.org/10.1177/0271678x20973951openalex-snapshot
Cerebral oxygen extraction fraction (OEF): Comparison of challenge-free gradient echo QSM+qBOLD (QQ) with 15 O PET in healthy adults
inferred← citeshttps://doi.org/10.1177/0271678x211012153openalex-snapshot
Impaired cerebral vascular and metabolic responses to parametric N-back tasks in subjective cognitive decline
inferred← citeshttps://doi.org/10.1177/0271678x211048031openalex-snapshot
Brain oxygen extraction fraction mapping in patients with multiple sclerosis
inferred← citeshttps://doi.org/10.1177/0271678x241259551openalex-snapshot
Reduced oxygen extraction fraction in deep cerebral veins associated with cognitive impairment in multiple sclerosis
inferred← citeshttps://doi.org/10.1177/0271678x241298584openalex-snapshot
Sensitivity assessment of QSM+qBOLD (or QQ) in detecting elevated oxygen extraction fraction (OEF) in physiological change
inferred← citeshttps://doi.org/10.1177/0271678x261418928openalex-snapshot
Remyelination and its association with increased oxygen extraction fraction in acute multiple sclerosis lesions
inferred← citeshttps://doi.org/10.1186/s12968-019-0579-7openalex-snapshot
Free breathing three-dimensional cardiac quantitative susceptibility mapping for differential cardiac chamber blood oxygenation – initial validation in patients with cardiovascular disease inclusive of direct comparison to invasive catheterization
inferred← citeshttps://doi.org/10.2174/1872208313666181217112745openalex-snapshot
Patents on Quantitative Susceptibility Mapping (QSM) of Tissue Magnetism
inferred← citeshttps://doi.org/10.22215/etd/2025-16494openalex-snapshot
Separating the vascular and nonvascular sources of magnetic susceptibility in physiological MRI techniques based on the reversible transverse relaxation rate, R2’
inferred← citeshttps://doi.org/10.3171/2020.6.jns20776openalex-snapshot
Incidence and characteristics of cerebral hypoxia after craniectomy in brain-injured patients: a cohort study
inferred← citeshttps://doi.org/10.3389/fnins.2020.535441openalex-snapshot
Initial Experience of Challenge-Free MRI-Based Oxygen Extraction Fraction Mapping of Ischemic Stroke at Various Stages: Comparison With Perfusion and Diffusion Mapping
inferred← citeshttps://doi.org/10.3389/fphys.2022.896006openalex-snapshot
Anemia Increases Oxygen Extraction Fraction in Deep Brain Structures but Not in the Cerebral Cortex
inferred← citeshttps://doi.org/10.3390/bioengineering11020131openalex-snapshot
Multi-Echo Complex Quantitative Susceptibility Mapping and Quantitative Blood Oxygen Level-Dependent Magnitude (mcQSM + qBOLD or mcQQ) for Oxygen Extraction Fraction (OEF) Mapping
inferred← citeshttps://doi.org/10.3390/metabo12090882openalex-snapshot
Impaired Neurovascular Function Underlies Poor Neurocognitive Outcomes and Is Associated with Nitric Oxide Bioavailability in Congenital Heart Disease
inferred← citeshttps://doi.org/10.3390/tomography12040046openalex-snapshot
MRI Quantification of Liver Fibrosis Using Diamagnetic Susceptibility: An Ex Vivo Validation Study
inferred← citeshttps://doi.org/10.70675/babd1081z7798z49beza02fze6c734c8fad5openalex-snapshot
Quantification simultanée de la diffusion et de la perfusion cérébrale en imagerie par résonance magnétique : application au diagnostic de l’accident vasculaire cérébral ischémique.
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