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High‐energy water sites determine peptide binding affinity and specificity of PDZ domains
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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What role do surfaces play in GB models? A new‐generation of surface‐generalized born model based on a novel gaussian surface for biomolecules
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Crystal structure of the PDZ1 domain of human Na+/H+ exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains
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Optimizing Dvl PDZ domain inhibitor by exploring chemical space
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The mitochondrial death squad: hardened killers or innocent bystanders?
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Quantification of PDZ Domain Specificity, Prediction of Ligand Affinity and Rational Design of Super-binding Peptides
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The schizophrenic faces of PICK1
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Classification of PDZ domains
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On the Role of the Crystal Environment in Determining Protein Side-chain Conformations
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Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ
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Identification of a Specific Inhibitor of the Dishevelled PDZ Domain
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MM-GB/SA Rescoring of Docking Poses in Structure-Based Lead Optimization
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A Flexible Docking Procedure for the Exploration of Peptide Binding Selectivity to Known Structures and Homology Models of PDZ Domains
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Entropy−Enthalpy Compensation in Solvation and Ligand Binding Revisited
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Convergent and Divergent Ligand Specificity among PDZ Domains of the LAP and Zonula Occludens (ZO) Families
inferredcites →https://doi.org/10.1093/bioinformatics/bti098openalex-snapshot
PDZBase: a protein–protein interaction database for PDZ-domains
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SMART: a web-based tool for the study of genetically mobile domains
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The RCSB Protein Data Bank: a redesigned query system and relational database based on the mmCIF schema
inferredcites →https://doi.org/10.1110/ps.072833207openalex-snapshot
Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain
inferredcites →https://doi.org/10.1110/ps.073049407openalex-snapshot
Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3
inferredcites →https://doi.org/10.1111/j.1600-0854.2008.00761.xopenalex-snapshot
Membrane Localization is Critical for Activation of the PICK1 BAR Domain
inferredcites →https://doi.org/10.1126/science.275.5296.73openalex-snapshot
Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains
inferredcites →https://doi.org/10.1126/science.286.5438.295openalex-snapshot
Evolutionarily Conserved Pathways of Energetic Connectivity in Protein Families
inferredcites →https://doi.org/10.1126/stke.2003.179.re7openalex-snapshot
PDZ Domain Proteins: Plug and Play!
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Molecular dynamics---Scalable algorithms for molecular dynamics simulations on commodity clusters
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An Antagonist of Dishevelled Protein-Protein Interaction Suppresses β-Catenin–Dependent Tumor Cell Growth
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Mechanism and role of PDZ domains in signaling complex assembly
inferredcites →https://doi.org/10.1358/dnp.2008.21.3.1203409openalex-snapshot
Therapeutic Use of PDZ Protein�Protein Interaction Antagonism
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A Specificity Map for the PDZ Domain Family
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The PDZ Domain as a Complex Adaptive System
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Structure and Function of HtrA Family Proteins, the Key Players in Protein Quality Control
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The cellular distribution of Na+/H+ exchanger regulatory factor 1 is determined by the PDZ-I domain and regulates the malignant progression of breast cancer
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Structural basis for the identification of short novel peptides as potential GLP1R agonists using in silico approaches
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Current Computational Methods for Protein-peptide Complex Structure Prediction
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Computational Insights into Binding of Bisphosphates to Farnesyl Pyrophosphate Synthase
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Advances in the Treatment of Explicit Water Molecules in Docking and Binding Free Energy Calculations
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The Advances and Limitations of the Determination and Applications of Water Structure in Molecular Engineering
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Leveraging the Fragment Molecular Orbital Method to Explore the PLK1 Kinase Binding Site and Polo-Box Domain for Potent Small-Molecule Drug Design
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Water Thermodynamics of Peptide Toxin Binding Sites on Ion Channels
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The Many Contributions to Protein-Ligand Binding: Implications in Drug Design
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