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Metallothionein isoform 3 expression inhibits cell growth and increases drug resistance of PC‐3 prostate cancer cells
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1097-0045(19980601)35:4<285::aid-pros8>3.0.co;2-fopenalex-snapshot
Novel role of zinc in the regulation of prostate citrate metabolism and its implications in prostate cancer
inferredcites →https://doi.org/10.1002/(sici)1097-0045(19990801)40:3<200::aid-pros8>3.0.co;2-3openalex-snapshot
Inhibitory effect of zinc on human prostatic carcinoma cell growth
inferredcites →https://doi.org/10.1002/(sici)1097-0045(19991101)41:3<196::aid-pros7>3.0.co;2-uopenalex-snapshot
Metallothionein isoform 3 expression in the human prostate and cancer-derived cell lines
inferredcites →https://doi.org/10.1002/(sici)1097-0045(20000501)43:2<125::aid-pros7>3.0.co;2-sopenalex-snapshot
Metallothionein isoform 1 and 2 gene expression in the human prostate: Downregulation of MT-1X in advanced prostate cancer
inferredcites →https://doi.org/10.1002/j.1460-2075.1992.tb05590.xopenalex-snapshot
Molecular cloning of human growth inhibitory factor cDNA and its down‐regulation in Alzheimer's disease.
inferredcites →https://doi.org/10.1006/bbrc.1995.2334openalex-snapshot
Modulation of Metallothionein-III mRNA Content and Growth Rate of Rat C6-Glial Cells by Transfection with Human 5-HT1D Receptor Genes
inferredcites →https://doi.org/10.1006/bbrc.2001.4594openalex-snapshot
Metallothionein-III Antagonizes the Neurotoxic and Neurotrophic Effects of Amyloid β Peptides
inferredcites →https://doi.org/10.1006/taap.1995.1216openalex-snapshot
Constitutive Expression of Metallothionein-III (MT-III), but Not MT-I, Inhibits Growth When Cells Become Zinc Deficient
inferredcites →https://doi.org/10.1006/taap.1996.0253openalex-snapshot
Induction of Metallothionein mRNA and Protein in Primary Murine Neuron Cultures
inferredcites →https://doi.org/10.1006/taap.1996.8054openalex-snapshot
Metallothioneins in Brain—The Role in Physiology and Pathology
inferredcites →https://doi.org/10.1016/0896-6273(91)90272-2openalex-snapshot
The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein
inferredcites →https://doi.org/10.1016/s0002-9440(10)61668-9openalex-snapshot
Metallothionein Isoform 3 Overexpression Is Associated with Breast Cancers Having a Poor Prognosis
inferredcites →https://doi.org/10.1016/s0006-8993(98)00239-xopenalex-snapshot
Stimulatory effects of 4-methylcatechol, dopamine and levodopa on the expression of metallothionein-III (GIF) mRNA in immortalized mouse brain glial cells (VR-2g)
inferredcites →https://doi.org/10.1016/s0009-2797(97)00165-8openalex-snapshot
The protein thiol metallothionein as an antioxidant and protectant against antineoplastic drugs
inferredcites →https://doi.org/10.1016/s0022-3565(24)35291-7openalex-snapshot
Metallothionein Acts as a Cytoprotectant against Doxorubicin Toxicity
inferredcites →https://doi.org/10.1016/s0165-3806(99)00063-2openalex-snapshot
Regulation of metallothionein-3 mRNA by thyroid hormone in developing rat brain and primary cultures of rat astrocytes and neurons
inferredcites →https://doi.org/10.1016/s0169-328x(97)00087-9openalex-snapshot
Transgenic expression of interleukin 6 in the central nervous system regulates brain metallothionein-I and -III expression in mice
inferredcites →https://doi.org/10.1016/s0378-4274(99)00003-xopenalex-snapshot
Expression of MT-3 protein in the human kidney
inferredcites →https://doi.org/10.1021/bi00014a031openalex-snapshot
Bioactivity of Metallothionein-3 Correlates with Its Novel .beta. Domain Sequence Rather Than Metal Binding Properties
inferredcites →https://doi.org/10.1046/j.1432-1327.2000.01167.xopenalex-snapshot
Characterization of cis‐acting elements in the promoter of the mouse metallothionein‐3 gene
inferredcites →https://doi.org/10.1073/pnas.89.14.6333openalex-snapshot
MT-III, a brain-specific member of the metallothionein gene family.
inferredcites →https://doi.org/10.1146/annurev.pa.35.040195.003223openalex-snapshot
Metallothioneins and Cell Death by Anticancer Drugs
inferredcites →https://doi.org/10.1289/ehp.00108413openalex-snapshot
Metallothionein Isoform 3 as a Potential Biomarker for Human Bladder Cancer
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4654986openalex-extracted
Joint Forces of Mass Spectrometric Techniques (Icp-Ms and Maldi-Tof-Ms) and Fluorescence Spectrometry in the Study of Platinum-Based Cytostatic Drugs Interactions with Metallothionein Mt2 and Mt3
inferred← citeshttps://doi.org/10.1002/pros.22697openalex-snapshot
Metallothionein 3: An androgen‐upregulated gene enhances cell invasion and tumorigenesis of prostate carcinoma cells
inferred← citeshttps://doi.org/10.1007/978-1-4020-8442-3_33openalex-snapshot
Prognostic Markers in Prostatic Carcinoma
inferred← citeshttps://doi.org/10.1007/978-3-319-27472-0_4openalex-snapshot
The Role of Metallothioneins in Carcinogenesis
inferred← citeshttps://doi.org/10.1007/s00775-009-0557-xopenalex-snapshot
Reaction of human metallothionein-3 with cisplatin and transplatin
inferred← citeshttps://doi.org/10.1007/s00775-011-0799-2openalex-snapshot
Chemistry and biology of mammalian metallothioneins
inferred← citeshttps://doi.org/10.1007/s12022-013-9280-9openalex-snapshot
Metallothionein-3 (MT-3) in the Human Adrenal Cortex and its Disorders
inferred← citeshttps://doi.org/10.1016/j.bcp.2026.117689openalex-snapshot
Deciphering the role of zinc in prostate health: From mechanism to therapeutic application
inferred← citeshttps://doi.org/10.1016/j.cellbi.2005.05.008openalex-snapshot
Effect of metallothionein on cell viability and its interactions with cadmium and zinc in HEK293 cells
inferred← citeshttps://doi.org/10.1016/j.drup.2020.100691openalex-snapshot
Metallothionein isoforms as double agents – Their roles in carcinogenesis, cancer progression and chemoresistance
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2003.12.014openalex-snapshot
The transcriptosomal response of human A549 lung cells to a hydrogen peroxide-generating system: relationship to DNA damage, cell cycle arrest, and caspase activation
inferred← citeshttps://doi.org/10.1016/j.yexcr.2004.01.013openalex-snapshot
Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior
inferred← citeshttps://doi.org/10.1021/acsnano.1c01172openalex-snapshot
Efficient Protein Transfection by Swarms of Chemically Powered Plasmonic Virus-Sized Nanorobots
inferred← citeshttps://doi.org/10.1023/a:1024520801262openalex-snapshot
Stable Transfection and Overexpression of Metallothionein Isoform 3 Inhibits the Growth of MCF-7 and Hs578T Cells but not that of T-47D or MDA-MB-231 Cells
inferred← citeshttps://doi.org/10.1038/s41598-021-84185-xopenalex-snapshot
Metallothionein-3 promotes cisplatin chemoresistance remodelling in neuroblastoma
inferred← citeshttps://doi.org/10.1038/sj.onc.1210041openalex-snapshot
Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer
inferred← citeshttps://doi.org/10.1039/9781847559531-00319openalex-snapshot
Metallothionein-3, Zinc, and Copper in the Central Nervous System
inferred← citeshttps://doi.org/10.1080/02772241003711274openalex-snapshot
Absence of metallothionein 3 expression in breast cancer is a rare but favorable marker that is under epigenetic control
inferred← citeshttps://doi.org/10.1093/toxsci/kfi231openalex-snapshot
Expression of Metallothoinein Isoform 3 Is Restricted at the Post-Transcriptional Level in Human Bladder Epithelial Cells
inferred← citeshttps://doi.org/10.1093/toxsci/kfl065openalex-snapshot
Enhanced Expression of Metallothionein Isoform 3 Protein in Tumor Heterotransplants Derived from As+3- and Cd+2-Transformed Human Urothelial Cells
inferred← citeshttps://doi.org/10.1097/00029330-200710010-00014openalex-snapshot
Effects of emodin on gene expression profile in small cell lung cancer NCI-H446 cells
inferred← citeshttps://doi.org/10.1110/ps.041113005openalex-snapshot
Identification of mouse brain proteins associated with isoform 3 of metallothionein
inferred← citeshttps://doi.org/10.1111/j.1365-2559.2004.01922.xopenalex-snapshot
Metallothionein expression in human neoplasia
inferred← citeshttps://doi.org/10.1136/jcp.2005.033746openalex-snapshot
Metallothionein isoform II expression in hyperplastic, dysplastic and neoplastic prostatic lesions
inferred← citeshttps://doi.org/10.11606/t.23.2014.tde-11092014-155417openalex-snapshot
Expressão gênica funcional das metalotioneínas no carcinoma epidermóide bucal
inferred← citeshttps://doi.org/10.1186/1476-4598-4-42openalex-snapshot
Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation
inferred← citeshttps://doi.org/10.1186/1476-4598-7-7openalex-snapshot
Differential expression of metallothioneins (MTs) 1, 2, and 3 in response to zinc treatment in human prostate normal and malignant cells and tissues
inferred← citeshttps://doi.org/10.1186/1756-6614-5-26openalex-snapshot
Role of metallothioneins in benign and malignant thyroid lesions
inferred← citeshttps://doi.org/10.1186/s13045-018-0645-xopenalex-snapshot
The roles of metallothioneins in carcinogenesis
inferred← citeshttps://doi.org/10.1201/9781420038866-13openalex-snapshot
Metal Ions as Endocrine Disruptors: Implications for Prostate Cancer
inferred← citeshttps://doi.org/10.1201/9781420038866.ch13openalex-snapshot
Metal Ions as Endocrine Disruptors
inferred← citeshttps://doi.org/10.1371/journal.pone.0124865openalex-snapshot
Metallothionein-3 Increases Triple-Negative Breast Cancer Cell Invasiveness via Induction of Metalloproteinase Expression
inferred← citeshttps://doi.org/10.18632/oncotarget.23333openalex-snapshot
Comparative gene expression profiling of human metallothionein-3 up-regulation in neuroblastoma cells and its impact on susceptibility to cisplatin
inferred← citeshttps://doi.org/10.21608/ejhm.2005.18106openalex-snapshot
Immunohistochemical Study of Metallothionein Isoform II in Hyperplastic,Dysplastic and Neoplastic Prostatic Lesions
inferred← citeshttps://doi.org/10.2164/jandrol.110.011205openalex-snapshot
Castration‐ and Aging‐Induced Changes in the Expression of Zinc Transporter and Metallothionein in Rat Prostate
inferred← citeshttps://doi.org/10.21873/anticanres.13059openalex-snapshot
Expression of Metallothionein I/II and Ki-67 Antigen in Graves' Disease
inferred← citeshttps://doi.org/10.3390/ijms20040980openalex-snapshot
Metallothionein 3 Is a Hypoxia-Upregulated Oncogene Enhancing Cell Invasion and Tumorigenesis in Human Bladder Carcinoma Cells
inferred← citeshttps://doi.org/10.33915/etd.1872openalex-snapshot
Metallothionein gene expression in human breast cancer
inferred← citeshttps://doi.org/10.33915/etd.1932openalex-snapshot
Metallothionein isoform 3 expression in human bladder urothelium
inferred← citeshttps://doi.org/10.3892/br.2013.107openalex-snapshot
Suppression of metallothionein 3 gene expression by androgen in LNCaP prostate cancer cells
inferred← citeshttps://doi.org/10.3892/ijo.2016.3759openalex-snapshot
Expression of metallothionein 3 in ductal breast cancer
inferred← citeshttps://doi.org/10.3892/or.18.5.1145openalex-snapshot
Metallothionein is up-regulated under hypoxia and promotes the survival of human prostate cancer cells
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