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Mechanistic insights into the inhibition of prostate specific antigen by β‐lactam class compounds
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/1097-0045(20001001)45:2<132::aid-pros7>3.0.co;2-3openalex-snapshot
Enzymatic action of prostate-specific antigen (PSA or hK3): Substrate specificity and regulation by Zn2+, a tight-binding inhibitor
inferredcites →https://doi.org/10.1002/pro.5560050505openalex-snapshot
Structural investigation of the alpha‐1‐antichymotrypsin: Prostate‐specific antigen complex by comparative model building
inferredcites →https://doi.org/10.1002/pros.20531openalex-snapshot
Does PSA play a role as a promoting agent during the initiation and/or progression of prostate cancer?
inferredcites →https://doi.org/10.1002/prot.10232openalex-snapshot
A new test set for validating predictions of protein–ligand interaction
inferredcites →https://doi.org/10.1006/bbrc.1993.1506openalex-snapshot
Mitogenic Response of Osteoblast Cells to Prostate-Specific Antigen Suggests an Activation of Latent TGF-β and a Proteolytic Modulation of Cell Adhesion Receptors
inferredcites →https://doi.org/10.1016/0968-0896(95)00101-lopenalex-snapshot
Azetidin-2-one derivatives as inhibitors of thrombin
inferredcites →https://doi.org/10.1016/j.bmcl.2004.02.012openalex-snapshot
Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors
inferredcites →https://doi.org/10.1016/s0009-9120(03)00055-9openalex-snapshot
An overview of the kallikrein gene families in humans and other species: emerging candidate tumour markers
inferredcites →https://doi.org/10.1016/s0960-894x(01)00264-5openalex-snapshot
Inhibition of serine proteases: activity of 1,3-diazetidine-2,4-diones
inferredcites →https://doi.org/10.1016/s0968-0896(00)82155-0openalex-snapshot
Synthesis and β-lactamase inhibitory activity of 6-fluoropenicillanic acids
inferredcites →https://doi.org/10.1016/s0968-0896(01)00209-7openalex-snapshot
Design, synthesis and pharmacological evaluation of 3-benzylazetidine-2-one-based human chymase inhibitors
inferredcites →https://doi.org/10.1016/s0968-0896(99)00094-2openalex-snapshot
Synthesis and antiviral activity of monobactams inhibiting the human cytomegalovirus protease
inferredcites →https://doi.org/10.1016/s1074-5521(98)90004-7openalex-snapshot
Substrate specificity of prostate-specific antigen (PSA)
inferredcites →https://doi.org/10.1021/bi9816249openalex-snapshot
Inhibition of Elastase by N -Sulfonylaryl β-Lactams: Anatomy of a Stable Acyl−Enzyme Complex ,
inferredcites →https://doi.org/10.1021/bi990098yopenalex-snapshot
Mechanistic Insights into the Inhibition of Serine Proteases by Monocyclic Lactams,
inferredcites →https://doi.org/10.1021/ja044179fopenalex-snapshot
Bifunctional Lewis Acid-Nucleophile-Based Asymmetric Catalysis: Mechanistic Evidence for Imine Activation Working in Tandem with Chiral Enolate Formation in the Synthesis of β-Lactams
inferredcites →https://doi.org/10.1021/jm000145gopenalex-snapshot
Design, Synthesis, and Proposed Active Site Binding Analysis of Monocyclic 2-Azetidinone Inhibitors of Prostate Specific Antigen
inferredcites →https://doi.org/10.1021/jm061277yopenalex-snapshot
Diverse, High-Quality Test Set for the Validation of Protein−Ligand Docking Performance
inferredcites →https://doi.org/10.1021/ol025805lopenalex-snapshot
Bifunctional Asymmetric Catalysis: A Tandem Nucleophile/Lewis Acid Promoted Synthesis of β-Lactams
inferredcites →https://doi.org/10.1038/322192a0openalex-snapshot
Cephalosporin antibiotics can be modified to inhibit human leukocyte elastase
inferredcites →https://doi.org/10.1073/pnas.0601910103openalex-snapshot
Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
inferredcites →https://doi.org/10.1073/pnas.112332899openalex-snapshot
A clogged gutter mechanism for protease inhibitors
inferredcites →https://doi.org/10.1093/jnci/91.19.1635openalex-snapshot
Antiangiogenic Activity of Prostate-Specific Antigen
inferredcites →https://doi.org/10.1172/jci112185openalex-snapshot
A kallikrein-like serine protease in prostatic fluid cleaves the predominant seminal vesicle protein.
inferredcites →https://doi.org/10.1210/jc.75.4.1046openalex-snapshot
Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4826457openalex-extracted
Synthesis, Characterization, and Biological Activity Using Computational Study of Synthesized Monocyclic Β-Lactam Ligands
inferred← citeshttps://doi.org/10.1002/0471266949.bmc226.pub2openalex-snapshot
Medicinal Chemistry of β‐Lactam Antibiotics
inferred← citeshttps://doi.org/10.1002/med.21451openalex-snapshot
Inhibitors of kallikrein‐related peptidases: An overview
inferred← citeshttps://doi.org/10.1002/pros.20773openalex-snapshot
Novel small molecule inhibitors for prostate‐specific antigen
inferred← citeshttps://doi.org/10.1002/prot.22524openalex-snapshot
Molecular insights into substrate specificity of prostate specific antigen through structural modeling
inferred← citeshttps://doi.org/10.1002/slct.202000552openalex-snapshot
Stereoselective Synthesis of Novel Monocyclic cis‐β‐Lactams Bearing 1,3,4‐Thiadiazole Nucleus: Bioactive Agents and Potential Synthons
inferred← citeshttps://doi.org/10.1007/s11030-020-10099-xopenalex-snapshot
Synthesis and antimicrobial activities of some novel diastereoselective monocyclic cis-β-lactams using 2-ethoxy carbonyl DCPN as a carboxylic acid activator
inferred← citeshttps://doi.org/10.1007/s44371-025-00235-7openalex-snapshot
Synthesis, characterization, and biological activity using computational study of synthesized monocyclic β-lactam ligands
inferred← citeshttps://doi.org/10.1016/j.bioorg.2012.08.001openalex-snapshot
In vitro evaluation of the antielastase activity of polycyclic β-lactams
inferred← citeshttps://doi.org/10.1016/j.bmc.2009.06.012openalex-snapshot
Optimization of peptide-based inhibitors of prostate-specific antigen (PSA) as targeted imaging agents for prostate cancer
inferred← citeshttps://doi.org/10.1016/j.chembiol.2008.05.020openalex-snapshot
Potent and Selective Peptidyl Boronic Acid Inhibitors of the Serine Protease Prostate-Specific Antigen
inferred← citeshttps://doi.org/10.1016/j.ejmech.2020.112510openalex-snapshot
β-Lactams as promising anticancer agents: Molecular hybrids, structure activity relationships and potential targets
inferred← citeshttps://doi.org/10.1016/j.molcatb.2015.11.011openalex-snapshot
Enantioselective hydrolysis of 3,4-disubstituted β-lactams. An efficient enzymatic method for the preparation of a key Taxol side-chain intermediate
inferred← citeshttps://doi.org/10.1016/j.molstruc.2020.128638openalex-snapshot
An efficient and eco-friendly synthesis, computational assay and antimicrobial evaluation of some novel diastereoselective monocyclic cis-β-lactams
inferred← citeshttps://doi.org/10.1016/j.tips.2012.09.005openalex-snapshot
Targeting the kallikrein-related peptidases for drug development
inferred← citeshttps://doi.org/10.1016/s0959-6380(09)70008-xopenalex-snapshot
Chapter 4: Four-Membered Ring Systems
inferred← citeshttps://doi.org/10.1016/s0959-6380(09)70031-5openalex-snapshot
Chapter 4: Four-Membered Ring Systems
inferred← citeshttps://doi.org/10.1021/acsmedchemlett.4c00257openalex-snapshot
Synthesis and Optimization of Small Molecule Inhibitors of Prostate Specific Antigen
inferred← citeshttps://doi.org/10.1021/bi9001858openalex-snapshot
Prostate-Specific Antigen Is a “Chymotrypsin-like” Serine Protease with Unique P1 Substrate Specificity
inferred← citeshttps://doi.org/10.1021/ci500371copenalex-snapshot
Structure-Based Drug Design of Diphenyl α-Aminoalkylphosphonates as Prostate-Specific Antigen Antagonists
inferred← citeshttps://doi.org/10.1039/9781849733151-00199openalex-snapshot
Pharmacological Targeting of Human Tissue Kallikrein-Related Peptidases
inferred← citeshttps://doi.org/10.1039/d3ra08550copenalex-snapshot
Synergistic acceleration of machine learning and molecular docking for prostate-specific antigen ligand design
inferred← citeshttps://doi.org/10.1093/biolre/ioaa075openalex-snapshot
Mechanism of semen liquefaction and its potential for a novel non-hormonal contraception†
inferred← citeshttps://doi.org/10.1515/bc.2010.044openalex-snapshot
Prostate-specific antigen: an overlooked candidate for the targeted treatment and selective imaging of prostate cancer
inferred← citeshttps://doi.org/10.20381/ruor-4753openalex-snapshot
Development of Biomolecular Tools for Studying Host-Virus Interactions of the Hepatitis C Virus
inferred← citeshttps://doi.org/10.21203/rs.3.rs-4365126/v1openalex-snapshot
Synthesis, characterization, and biological activity using computational study of synthesized monocyclic β-lactam ligands
inferred← citeshttps://doi.org/10.2174/1871520610909030276openalex-snapshot
A Trojan Horse in Drug Development: Targeting of Thapsigargins Towards Prostate Cancer Cells
inferred← citeshttps://doi.org/10.2741/4684openalex-snapshot
Hsp70 and gama-Semino protein as possible prognostic marker of prostate cancer
inferred← citeshttps://doi.org/10.3390/antibiotics14010009openalex-snapshot
Unraveling the Anti-Cancer Mechanisms of Antibiotics: Current Insights, Controversies, and Future Perspectives
inferred← citeshttps://doi.org/10.70675/95d49fabz6ca4z4b31z8099zc3c87d8000b4openalex-snapshot
Modulateurs synthétiques de la kallikréine 6, protéase à sérine impliquée dans les maladies neurodégénératives : identification, mécanisme d’action et validation de concept
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