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Effect of hydrophobic and hydrogen bonding interactions on the potency of ß‐alanine analogs of G‐protein coupled glucagon receptor inhibitors

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function
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Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges
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Biaryl amide glucagon receptor antagonists
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Discovery and investigation of a novel class of thiophene-derived antagonists of the human glucagon receptor
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A novel series of glucagon receptor antagonists with reduced molecular weight and lipophilicity
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The design and synthesis of a potent glucagon receptor antagonist with favorable physicochemical and pharmacokinetic properties as a candidate for the treatment of type 2 diabetes mellitus
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inferredcites →https://doi.org/10.1152/ajpendo.00492.2002openalex-snapshot
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inferredcites →https://doi.org/10.1517/13543776.2011.587001openalex-snapshot
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Two Rules on the Protein-Ligand Interaction

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