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Differential expression of cytochrome P450 genes between bromadiolone‐resistant and anticoagulant‐susceptible Norway rats: a possible role for pharmacokinetics in bromadiolone resistance

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bdd.442openalex-snapshot
Gender differences in pharmacokinetics of oral warfarin in rats
inferredcites →https://doi.org/10.1002/ps.2780430110openalex-snapshot
Resistance to anticoagulant rodenticides in Germany and future strategies to control Rattus norvegicus
inferredcites →https://doi.org/10.1002/ps.2780430112openalex-snapshot
Warfarin‐based rodenticides: Mode of action and mechanism of resistance
inferredcites →https://doi.org/10.1002/ps.703openalex-snapshot
Vitamin K requirement in Danish anticoagulant‐resistant Norway rats (Rattus norvegicus)
inferredcites →https://doi.org/10.1006/meth.2001.1262openalex-snapshot
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
inferredcites →https://doi.org/10.1007/s003359901073openalex-snapshot
Genomic assignment of the warfarin resistance locus, Rw, in the rat
inferredcites →https://doi.org/10.1016/0003-9861(83)90045-0openalex-snapshot
Comparisons of warfarin metabolism by liver microsomes of rats treated with a series of polybrominated biphenyl congeners and by the component-purified cytochrome P-450 isozymes
inferredcites →https://doi.org/10.1016/0003-9861(83)90087-5openalex-snapshot
Sex difference of cytochrome P-450 in the rat: Purification, characterization, and quantitation of constitutive forms of cytochrome P-450 from liver microsomes of male and female rats
inferredcites →https://doi.org/10.1016/0003-9861(89)90527-4openalex-snapshot
Identification of cytochrome P450a (P450IIA1) as the principal testosterone 7α-hydroxylase in rat liver microsomes and its regulation by thyroid hormones
inferredcites →https://doi.org/10.1016/0006-2952(74)90002-1openalex-snapshot
Biochemical basis of hereditary resistance to warfarin in the rat
inferredcites →https://doi.org/10.1016/0006-2952(75)90251-8openalex-snapshot
Studies of the microsomal drug metabolism system in warfarin-resistant and -susceptible rats
inferredcites →https://doi.org/10.1016/0006-2952(81)90182-9openalex-snapshot
A comparative study of the effects of warfarin and brodifacoum on the relationship between vitamin K1, metabolism and clotting factor activity in warfarin-susceptible and warfarin-resistant rats
inferredcites →https://doi.org/10.1016/0006-2952(86)90340-0openalex-snapshot
Sexually dimorphic response of rat hepatic monooxygenases to low-dose phenobarbital
inferredcites →https://doi.org/10.1016/0006-2952(88)90756-3openalex-snapshot
Interactions of hepatic cytochromes P-450 with steroid hormones
inferredcites →https://doi.org/10.1016/0009-2797(86)90044-xopenalex-snapshot
Sex differences in drug conjugation and their consequences for drug toxicity. Sulfation, glucuronidation and gluthatione conjugation
inferredcites →https://doi.org/10.1016/0014-5793(73)80869-5openalex-snapshot
A conformational study of normal and dicoumarol‐induced prothrombin
inferredcites →https://doi.org/10.1016/0014-5793(93)80470-fopenalex-snapshot
Molecular evolution of P450 superfamily and P450‐containing monooxygenase systems
inferredcites →https://doi.org/10.1016/0304-4165(85)90156-4openalex-snapshot
A comparison of warfarin resistance and liver microsomal vitamin K epoxide reductase activity in rats
inferredcites →https://doi.org/10.1016/0925-4439(91)90034-7openalex-snapshot
Age-dependent exression of cytochrome P-450s in rat liver
inferredcites →https://doi.org/10.1016/j.pestbp.2007.01.003openalex-snapshot
Involvement of hepatic xenobiotic related genes in bromadiolone resistance in wild Norway rats, Rattus norvegicus (Berk.)
inferredcites →https://doi.org/10.1016/s0006-2952(97)00264-5openalex-snapshot
Developmental changes in the constitutive and inducible expression of cytochrome p450 3a2
inferredcites →https://doi.org/10.1016/s0021-9258(17)42567-1openalex-snapshot
Purification, characterization, and pituitary regulation of the sex-specific cytochrome P-450 15 beta-hydroxylase from liver microsomes of untreated female rats.
inferredcites →https://doi.org/10.1016/s0021-9258(19)47251-7openalex-snapshot
Hormonal Regulation of Male-specific Rat Hepatic Cytochrome P-450g (P-450IIC13) by Androgens and the Pituitary
inferredcites →https://doi.org/10.1016/s0021-9258(19)70085-4openalex-snapshot
Regulation of three forms of cytochrome P-450 and epoxide hydrolase in rat liver microsomes. Effects of age, sex, and induction.
inferredcites →https://doi.org/10.1016/s0021-9258(19)86267-1openalex-snapshot
Comparison of different forms of purified cytochrome P-450 from rat liver by immunological inhibition of regio- and stereoselective metabolism of warfarin.
inferredcites →https://doi.org/10.1016/s0022-3565(25)21136-3openalex-snapshot
Age-related alteration in the activities of drug-metabolizing enzymes and contents of sex-specific forms of cytochrome P-450 in liver microsomes from male and female rats.
inferredcites →https://doi.org/10.1016/s0163-7258(96)00140-4openalex-snapshot
Human P450 metabolism of warfarin
inferredcites →https://doi.org/10.1021/bi00266a045openalex-snapshot
Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone
inferredcites →https://doi.org/10.1021/bi00601a003openalex-snapshot
Mechanism of coumarin action: significance of vitamin K epoxide reductase inhibition
inferredcites →https://doi.org/10.1021/bi00733a015openalex-snapshot
Mechanism of warfarin resistance. Warfarin and the metabolism of vitamin K1
inferredcites →https://doi.org/10.1038/188517a0openalex-snapshot
Case of Apparent Resistance of Rattus norvegicus Berkenhout to Anticoagulant Poisons
inferredcites →https://doi.org/10.1038/203778a0openalex-snapshot
Resistance to Warfarin in the Common Rat
inferredcites →https://doi.org/10.1038/215877a0openalex-snapshot
Heritable Resistance to Warfarin in Rats
inferredcites →https://doi.org/10.1038/nature02214openalex-snapshot
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
inferredcites →https://doi.org/10.1038/nature02254openalex-snapshot
Identification of the gene for vitamin K epoxide reductase
inferredcites →https://doi.org/10.1074/jbc.270.22.13262openalex-snapshot
Intermittent Plasma Growth Hormone Triggers Tyrosine Phosphorylation and Nuclear Translocation of a Liver-Expressed, Stat 5-related DNA Binding Protein.
inferredcites →https://doi.org/10.1093/jn/104.6.660openalex-snapshot
Influence of Sex Hormones on Vitamin K Deficiency and Epoxidation of Vitamin K in the Rat
inferredcites →https://doi.org/10.1096/fasebj.6.2.1537461openalex-snapshot
Hepatic steroid hydroxylating enzymes are controlled by the sexually dimorphic pattern of growth hormone secretion in normal and dwarf rats
inferredcites →https://doi.org/10.1111/j.1365-2338.1993.tb00571.xopenalex-snapshot
Revised methodology for a blood‐clotting response test for identification of warfarin‐resistant Norway rats (Rattus norvegicus)
inferredcites →https://doi.org/10.1124/dmd.106.011775openalex-snapshot
Elevated Warfarin Metabolism in Warfarin-Resistant Roof Rats (Rattus rattus) in Tokyo
inferredcites →https://doi.org/10.1152/ajplegacy.1968.215.3.627openalex-snapshot
Warfarin resistance in the rat
inferredcites →https://doi.org/10.1152/ajplegacy.1969.217.5.1316openalex-snapshot
Warfarin metabolism and vitamin K requirement in the warfarin-resistant rat
inferredcites →https://doi.org/10.1159/000137881openalex-snapshot
Dispositional and Pharmacodynamic Characteristics of Brodifacoum in Warfarin-Sensitive Rats
inferredcites →https://doi.org/10.1182/blood.v96.5.1996openalex-snapshot
A gene-anchored map position of the rat warfarin-resistance locus, Rw, and its orthologs in mice and humans
inferredcites →https://doi.org/10.1210/me.2003-0138openalex-snapshot
Sexual Dimorphism of Rat Liver Gene Expression: Regulatory Role of Growth Hormone Revealed by Deoxyribonucleic Acid Microarray Analysis
inferredcites →https://doi.org/10.1534/genetics.104.040360openalex-snapshot
The Genetic Basis of Resistance to Anticoagulants in Rodents
inferredcites →https://doi.org/10.2307/3809316openalex-snapshot
Blood-Clotting Response Test for Bromadiolone Resistance in Norway Rats
inferredcites →https://doi.org/10.3109/03602539808996322openalex-snapshot
Sex-Dependent Metabolism of Xenobiotics

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4820673openalex-extracted
First Wide-Ranging Survey of Vkorc1 Missense Mutations in the Mediterranean Islands Reveals Widespread Rodenticide Resistance in House Mice
inferred← citeshttps://doi.org/10.1002/ece3.2829openalex-snapshot
Adaptative evolution of theVkorc1gene inMus musculus domesticusis influenced by the selective pressure of anticoagulant rodenticides
inferred← citeshttps://doi.org/10.1002/ps.1709openalex-snapshot
Anticoagulant resistance: a relevant issue in sewer rat (Rattus norvegicus) control?
inferred← citeshttps://doi.org/10.1002/ps.1869openalex-snapshot
Distribution of VKORC1 single nucleotide polymorphism in wild Rattus norvegicus in France
inferred← citeshttps://doi.org/10.1002/ps.4319openalex-snapshot
Study of the efficiency of anticoagulant rodenticides to control Mus musculus domesticus introgressed with Mus spretus Vkorc1
inferred← citeshttps://doi.org/10.1002/ps.4797openalex-snapshot
Elevated difenacoum metabolism is involved in the difenacoum‐resistant phenotype observed in Berkshire rats homozygous for the L120Q mutation in the vitamin K epoxide reductase complex subunit 1 ( Vkorc1 ) gene
inferred← citeshttps://doi.org/10.1002/ps.6780openalex-snapshot
Sanitary measures considerably improve the management of resistant Norway rats on livestock farms
inferred← citeshttps://doi.org/10.1002/rcm.8871openalex-snapshot
Mass spectrometry characterization of anticoagulant rodenticides and hydroxyl metabolites
inferred← citeshttps://doi.org/10.1007/s10340-020-01299-3openalex-snapshot
Sublethal dose of warfarin induction promotes the accumulation of warfarin resistance in susceptible Norway rats
inferred← citeshttps://doi.org/10.1007/s10646-011-0700-7openalex-snapshot
Are water vole resistant to anticoagulant rodenticides following field treatments?
inferred← citeshttps://doi.org/10.1016/b978-0-12-374367-1.00038-0openalex-snapshot
Metabolism of Pesticides
inferred← citeshttps://doi.org/10.1016/b978-0-12-374367-1.00100-2openalex-snapshot
Rodenticides
inferred← citeshttps://doi.org/10.1016/b978-0-12-385481-0.00005-8openalex-snapshot
Biotransformation (Metabolism) of Pesticides
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2022.133727openalex-snapshot
New insights on in vitro biotransformation of anticoagulant rodenticides in fish
inferred← citeshttps://doi.org/10.1016/j.cropro.2015.08.011openalex-snapshot
Increased diphacinone and chlorophacinone metabolism in previously exposed wild caught voles, Microtus californicus
inferred← citeshttps://doi.org/10.1016/j.cropro.2019.104969openalex-snapshot
Are reports of reduced field efficacy of diphacinone and chlorophacinone in California ground squirrels (Otospermophilus beecheyi) due to elevated rodenticide metabolism?
inferred← citeshttps://doi.org/10.1016/j.cropro.2020.105301openalex-snapshot
The Hampshire-Berkshire focus of L120Q anticoagulant resistance in the Norway rat (Rattus norvegicus) and field trials of bromadiolone, difenacoum and brodifacoum
inferred← citeshttps://doi.org/10.1016/j.envres.2010.07.009openalex-snapshot
Determination of bromadiolone residues in fox faeces by LC/ESI-MS in relationship with toxicological data and clinical signs after repeated exposure
inferred← citeshttps://doi.org/10.1016/j.jspr.2020.101688openalex-snapshot
Anticoagulant rodenticides and resistance development in rodent pest species – A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.pestbp.2008.03.004openalex-snapshot
Identification of cytochrome P450 differentiated expression related to developmental stages in bromadiolone resistance in rats (Rattus norvegicus)
inferred← citeshttps://doi.org/10.1016/j.pestbp.2016.04.004openalex-snapshot
Novel revelation of warfarin resistant mechanism in roof rats (Rattus rattus) using pharmacokinetic/pharmacodynamic analysis
inferred← citeshttps://doi.org/10.1016/j.pestbp.2017.02.003openalex-snapshot
Monitoring of antivitamin K-dependent anticoagulation in rodents – Towards an evolution of the methodology to detect resistance in rodents
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.176090openalex-snapshot
A survey of VKORC1 missense mutations in eleven Italian islands reveals widespread rodenticide resistance in house mice
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2026.181344openalex-snapshot
Rats, residues and rodenticide resistance: Hepatic concentration of anticoagulant rodenticides in genetically susceptible wild brown and black rats
inferred← citeshttps://doi.org/10.1016/j.tox.2016.02.002openalex-snapshot
Origin of the gender differences of the natural resistance to antivitamin K anticoagulants in rats
inferred← citeshttps://doi.org/10.1038/s41598-022-08653-8openalex-snapshot
VKORC1 mutations in rodent populations of a tropical city-state as an indicator of anticoagulant rodenticide resistance
inferred← citeshttps://doi.org/10.1071/wr21064openalex-snapshot
Apparent resistance to brodifacoum in Rattus rattus in a New Zealand site with no history of anticoagulant-based rodent control
inferred← citeshttps://doi.org/10.1079/9781800626508.0004openalex-snapshot
Resistance to Anticoagulant Rodenticides
inferred← citeshttps://doi.org/10.1097/fpc.0b013e32832ee55bopenalex-snapshot
Consequences of the Y139F Vkorc1 mutation on resistance to AVKs: in-vivo investigation in a 7th generation of congenic Y139F strain of rats
inferred← citeshttps://doi.org/10.1101/2021.01.22.426921openalex-snapshot
Computational ligands to VKORC1s and CYPs. Could they predict new anticoagulant rodenticides?
inferred← citeshttps://doi.org/10.1177/1040638720927365openalex-snapshot
Comparison of anticoagulant rodenticide concentrations in liver and feces from apparently healthy red foxes
inferred← citeshttps://doi.org/10.1201/9780849333927.ch2openalex-snapshot
Active Forms, Antagonists, Physical Properties, and Synthesis of Vitamin K
inferred← citeshttps://doi.org/10.1201/9781420005110.ch2openalex-snapshot
Active Forms, Antagonists, Physical Properties, and Synthesis of Vitamin K
inferred← citeshttps://doi.org/10.1201/9781420062595.bmatt1openalex-snapshot
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Endocrine Disruptors
inferred← citeshttps://doi.org/10.1360/n052016-00161openalex-snapshot
Genetic Mechanism of Resistance to Anticoagulant Rodent Poison in Rodents
inferred← citeshttps://doi.org/10.21203/rs.3.rs-691977/v1openalex-snapshot
Single Nucleotide Polymorphisms (SNPs) Within Vkorc1 in Rodent Populations in a Tropical City-state: Implications for Anticoagulant Rodenticide Use for Rodent Control
inferred← citeshttps://doi.org/10.26496/bjz.2012.135openalex-snapshot
Distribution of anticoagulant resistance in the brown rat in Belgium
inferred← citeshttps://doi.org/10.31857/s0002188124010042openalex-snapshot
Effectiveness of rodenticides based on bromadiolone against the common vole Microtus arvalis Pall. in laboratory conditions
inferred← citeshttps://doi.org/10.3389/fvets.2020.616276openalex-snapshot
Biomarkers Potency to Monitor Non-target Fauna Poisoning by Anticoagulant Rodenticides
inferred← citeshttps://doi.org/10.35376/10324/5740openalex-snapshot
Metodología multiresiduo para análisis de rodenticidas en muestras ambientales
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Comparative Biology of the Resistance to Vitamin K Antagonists: An Overview of the Resistance Mechanisms
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Gestion et maîtrise des risques liés aux rongeurs du Tchad
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Développement d’une nouvelle stratégie efficace et eco-compatible pour une lutte adaptée contre le campagnol terrestre en France.
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