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Design, synthesis and mode of action of novel 3‐ chloro‐6‐pyrazolyl picolinate derivatives as herbicide candidates

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Emil Fischer's Lock‐and‐Key Hypothesis after 100 years—Towards a Supracellular Chemistry
inferredcites →https://doi.org/10.1002/9783527619580openalex-snapshot
Modern Crop Protection Compounds
inferredcites →https://doi.org/10.1002/ps.2333openalex-snapshot
Why have no new herbicide modes of action appeared in recent years?
inferredcites →https://doi.org/10.1002/ps.3696openalex-snapshot
Global perspective of herbicide‐resistant weeds
inferredcites →https://doi.org/10.1002/ps.3918openalex-snapshot
Design, synthesis and herbicidal evaluation of novel 4‐(1H‐pyrazol‐1‐yl)pyrimidine derivatives
inferredcites →https://doi.org/10.1002/ps.4823openalex-snapshot
Weed resistance to synthetic auxin herbicides
inferredcites →https://doi.org/10.1002/ps.5584openalex-snapshot
Improved synthetic route of exo‐16,17‐dihydro‐gibberellin A5‐13‐acetate and the bioactivity of its derivatives towards Arabidopsis thaliana
inferredcites →https://doi.org/10.1002/ps.5591openalex-snapshot
Synthesis and herbicidal activity of novel pyrazole aromatic ketone analogs as HPPD inhibitor
inferredcites →https://doi.org/10.1006/meth.2001.1262openalex-snapshot
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
inferredcites →https://doi.org/10.1007/s00344-019-10030-1openalex-snapshot
Computational-Aided Discovery of Novel 1,3-Benzodioxole Plant Growth Retardants
inferredcites →https://doi.org/10.1016/j.bmc.2015.08.011openalex-snapshot
The discovery of Arylex™ active and Rinskor™ active: Two novel auxin herbicides
inferredcites →https://doi.org/10.1016/j.bmc.2019.06.032openalex-snapshot
Design, synthesis, biological activities, and dynamic simulation study of novel thiourea derivatives with gibberellin activity towards Arabidopsis thaliana
inferredcites →https://doi.org/10.1016/j.ejmech.2011.09.016openalex-snapshot
Synthesis of functionalized tetrasubstituted pyrazolyl heterocycles – A review
inferredcites →https://doi.org/10.1016/j.pestbp.2007.04.002openalex-snapshot
Recent developments in auxin biology and new opportunities for auxinic herbicide research
inferredcites →https://doi.org/10.1016/j.saa.2009.12.006openalex-snapshot
Synthesis, characterization and luminescence properties of Eu(III) and Tb(III) complexes with novel pyrazole derivatives and 1,10-phenanthroline
inferredcites →https://doi.org/10.1017/s004317450003037xopenalex-snapshot
Ecological and Control Studies of Musk Thistle
inferredcites →https://doi.org/10.1017/s0043174500047342openalex-snapshot
Reaction of Western Ironweed Leaf Tissue to Picloram
inferredcites →https://doi.org/10.1017/wsc.2018.21openalex-snapshot
Influence of Soil Moisture on Absorption, Translocation, and Metabolism of Florpyrauxifen-benzyl
inferredcites →https://doi.org/10.1021/acs.jafc.6b03977openalex-snapshot
Synthesis and Herbicidal Activities of p-Menth-3-en-1-amine and Its Schiff Base Derivatives
inferredcites →https://doi.org/10.1021/acs.jafc.9b02996openalex-snapshot
Design, Herbicidal Activity, and QSAR Analysis of Cycloalka[ d ]quinazoline-2,4-dione–Benzoxazinones as Protoporphyrinogen IX Oxidase Inhibitors
inferredcites →https://doi.org/10.1021/acs.jafc.9b03109openalex-snapshot
Design and Synthesis of Novel 4-Hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one Derivatives for Use as Herbicides and Evaluation of Their Mode of Action
inferredcites →https://doi.org/10.1021/acschembio.9b00453openalex-snapshot
Abscisic Acid Derivatives with Different Alkyl Chain Lengths Activate Distinct Abscisic Acid Receptor Subfamilies
inferredcites →https://doi.org/10.1021/bk-2015-1204.ch018openalex-snapshot
Discovery and SAR of Halauxifen Methyl: A Novel Auxin Herbicide
inferredcites →https://doi.org/10.1021/cr60153a002openalex-snapshot
Aromatic Nucleophilic Substitution Reactions.
inferredcites →https://doi.org/10.1021/es00106a605openalex-snapshot
Herbicides in agriculture
inferredcites →https://doi.org/10.1021/jf305153hopenalex-snapshot
α-(Substituted-phenoxyacetoxy)-α-heterocyclylmethylphosphonates: Synthesis, Herbicidal Activity, Inhibition on Pyruvate Dehydrogenase Complex (PDHc), and Application as Postemergent Herbicide against Broadleaf Weeds
inferredcites →https://doi.org/10.1038/326347a0openalex-snapshot
Knowledge-based prediction of protein structures and the design of novel molecules
inferredcites →https://doi.org/10.1038/nature03542openalex-snapshot
The Arabidopsis F-box protein TIR1 is an auxin receptor
inferredcites →https://doi.org/10.1038/nature05731openalex-snapshot
Mechanism of auxin perception by the TIR1 ubiquitin ligase
inferredcites →https://doi.org/10.1038/nchembio.926openalex-snapshot
A combinatorial TIR1/AFB–Aux/IAA co-receptor system for differential sensing of auxin
inferredcites →https://doi.org/10.1038/s41477-019-0395-yopenalex-snapshot
Considering weed management as a social dilemma bridges individual and collective interests
inferredcites →https://doi.org/10.1038/s41586-018-0319-4openalex-snapshot
Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action
inferredcites →https://doi.org/10.1038/s41598-018-29554-9openalex-snapshot
Developing dual herbicide tolerant transgenic rice plants for sustainable weed management
inferredcites →https://doi.org/10.1073/pnas.0711146105openalex-snapshot
Small-molecule agonists and antagonists of F-box protein–substrate interactions in auxin perception and signaling
inferredcites →https://doi.org/10.1105/tpc.105.031716openalex-snapshot
MicroRNA-Directed Regulation of Arabidopsis AUXIN RESPONSE FACTOR17 Is Essential for Proper Development and Modulates Expression of Early Auxin Response Genes
inferredcites →https://doi.org/10.1126/science.1122847openalex-snapshot
AXR4 Is Required for Localization of the Auxin Influx Facilitator AUX1
inferredcites →https://doi.org/10.1534/g3.115.025585openalex-snapshot
The Arabidopsis Auxin Receptor F-Box Proteins AFB4 and AFB5 Are Required for Response to the Synthetic Auxin Picloram
inferredcites →https://doi.org/10.1584/jpestics.j16-05openalex-snapshot
Development of the novel pre-emergence herbicide pyroxasulfone
inferredcites →https://doi.org/10.3390/molecules24030562openalex-snapshot
Design, Synthesis, and Biological Activities of Novel 1,3,5-Trimethylpyrazole-Containing Malonamide Derivatives

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Method Validation and Field Experiments of Oxyfluorfen and Two Derivates for Residues and Metabolic Mechanisms Out of Five Crops by Lc/Lc-Ms
inferred← citeshttps://doi.org/10.1007/s00344-022-10867-zopenalex-snapshot
Design, Synthesis and Herbicidal Evaluation of Novel Urea Derivatives with Inhibition Activity to Root Growth
inferred← citeshttps://doi.org/10.1007/s00344-026-12073-7openalex-snapshot
Design, Synthesis and Biological Activity of Pyridine-Containing Aryl Urea Derivatives
inferred← citeshttps://doi.org/10.1016/j.cej.2022.141145openalex-snapshot
Acute Responses of Bio-Denitrification to Short-Term Clopyralid Exposure: Kinetic Analysis and Biological Mechanisms
inferred← citeshttps://doi.org/10.1016/j.ejmech.2026.119321openalex-snapshot
Directed scaffold evolution of chrysin for the development of potent carboxylesterase 2 inhibitors
inferred← citeshttps://doi.org/10.1016/j.stress.2025.100951openalex-snapshot
Leveraging computer-aided drug design for the discovery of phytohormone analogs: A review
inferred← citeshttps://doi.org/10.1021/acs.jafc.1c06897openalex-snapshot
Design, Synthesis, Herbicidal Activity, and Molecular Docking Study of 2-Thioether-5-(Thienyl/Pyridyl)-1,3,4-Oxadiazoles as Potent Transketolase Inhibitors
inferred← citeshttps://doi.org/10.1021/acs.jafc.1c07910openalex-snapshot
A Competitive Edge: Competitor Inspired Scaffold Hopping in Herbicide Lead Optimization
inferred← citeshttps://doi.org/10.1021/acs.jafc.2c03758openalex-snapshot
Novel [1,2,4]-Triazolo[3,4-b]-[1,3,4]thiadizoles as Potent Pyruvate Kinase Inhibitors for Fungal Control
inferred← citeshttps://doi.org/10.1021/acs.jafc.3c00951openalex-snapshot
Carboxylic Acid Derivatives in Herbicide Development
inferred← citeshttps://doi.org/10.1021/acs.jafc.3c08517openalex-snapshot
Investigation into the Synthesis, Bioactivity, and Mechanism of Action of the Novel 6-Pyrazolyl-2-picolinic Acid as a Herbicide
inferred← citeshttps://doi.org/10.1021/acs.jafc.4c08993openalex-snapshot
Design, Synthesis, and Herbicidal Evaluation of Novel Synthetic Auxin Herbicides Containing 6-Indolylpyridine Oxime Ester/Amine
inferred← citeshttps://doi.org/10.1021/acs.jafc.4c11800openalex-snapshot
Design, Synthesis, and Herbicidal Activity of Novel 5-Acylbarbituric Acid Derivatives Containing Maleimide Moieties and Evaluation of Their Mode of Action
inferred← citeshttps://doi.org/10.1021/acs.jafc.5c00525openalex-snapshot
Synthesis, Biological Activity and Mechanism of Action of Pyridine-Containing Arylthiourea Derivatives
inferred← citeshttps://doi.org/10.1021/acs.jafc.5c08390openalex-snapshot
Advances in Pyrazole as an Active Fragment for Herbicide Discovery
inferred← citeshttps://doi.org/10.1021/acs.jafc.6c01648openalex-snapshot
Pocket-Oriented Design of Benzene-Fused Pyridinecarboxylates as Potent Synthetic Auxin Herbicides
inferred← citeshttps://doi.org/10.1021/acs.jafc.6c04528openalex-snapshot
Study on Design, Synthesis, and Herbicidal Activity of 4-Amino-3,5-dichloro-6-indolyl-2-picolinic Acids
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.2c01999openalex-snapshot
Novel Benzo Five-Membered Heterocycle Derivatives as P-Glycoprotein Inhibitors: Design, Synthesis, Molecular Docking, and Anti-Multidrug Resistance Activity
inferred← citeshttps://doi.org/10.1039/d4ob02057jopenalex-snapshot
Access to chiral phthalidyl ester prodrugs via an isothiourea-catalyzed dynamic kinetic resolution reaction
inferred← citeshttps://doi.org/10.1186/s40538-024-00646-1openalex-snapshot
Design, synthesis, pharmacophore modeling, and molecular docking of some novel chloroacetamide derivatives as herbicidal agents
inferred← citeshttps://doi.org/10.31993/2308-6459-2023-106-1openalex-snapshot
inferred← citeshttps://doi.org/10.31993/2308-6459-2023-106-1-15502openalex-snapshot
Prospects for the development of new herbicides based on natural compounds
inferred← citeshttps://doi.org/10.3389/fpls.2022.902902openalex-snapshot
Design, Synthesis, and Action Mechanism of 1,3-Benzodioxole Derivatives as Potent Auxin Receptor Agonists and Root Growth Promoters
inferred← citeshttps://doi.org/10.3390/molecules28031431openalex-snapshot
Design, Synthesis, Herbicidal Activity, and Structure–Activity Relationship Study of Novel 6-(5-Aryl-Substituted-1-Pyrazolyl)-2-Picolinic Acid as Potential Herbicides
inferred← citeshttps://doi.org/10.3390/molecules29020332openalex-snapshot
Study on Design, Synthesis and Herbicidal Activity of Novel 6-Indazolyl-2-picolinic Acids
inferred← citeshttps://doi.org/10.3390/molecules30051022openalex-snapshot
Study on Design, Synthesis and Herbicidal Activity of Novel 4-Amino-6-(5-Aryl-Substituted-1-Pyrazolyl)-3-Chloro-5-Fluoro-2-Picolinic Acids
inferred← citeshttps://doi.org/10.3390/plants12020234openalex-snapshot
Modern Approaches for the Development of New Herbicides Based on Natural Compounds
inferred← citeshttps://doi.org/10.5772/intechopen.1009023openalex-snapshot
Editing the Future: CRISPR/Cas9 for Climate-Resilient Crops
inferred← citeshttps://doi.org/10.6084/m9.figshare.26943909openalex-snapshot
Additional file 1 of Design, synthesis, pharmacophore modeling, and molecular docking of some novel chloroacetamide derivatives as herbicidal agents
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.