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Pharmacometrics of pterostilbene: preclinical pharmacokinetics and metabolism, anticancer, antiinflammatory, antioxidant and analgesic activity

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bmc.342openalex-snapshot
Determination of piceatannol in rat serum and liver microsomes: pharmacokinetics and phase I and II biotransformation
inferredcites →https://doi.org/10.1002/mnfr.200500010openalex-snapshot
Metabolism and bioavailability oftrans-resveratrol
inferredcites →https://doi.org/10.1002/mnfr.200600135openalex-snapshot
Inhibition of human recombinant cytochromes P450 CYP1A1 and CYP1B1 bytrans‐resveratrol methyl ethers
inferredcites →https://doi.org/10.1006/jfca.2001.1041openalex-snapshot
Effects of Harvesting Time on Triacylglycerols and Glycerophospholipids of Sea Buckthorn (Hippophaë rhamnoides L.) Berries of Different Origins
inferredcites →https://doi.org/10.1016/j.bcp.2004.04.028openalex-snapshot
Transport of resveratrol, a cancer chemopreventive agent, to cellular targets: plasmatic protein binding and cell uptake
inferredcites →https://doi.org/10.1016/j.bcp.2006.08.028openalex-snapshot
Anti-allodynic property of flavonoid myricitrin in models of persistent inflammatory and neuropathic pain in mice
inferredcites →https://doi.org/10.1016/j.biocel.2005.03.004openalex-snapshot
Pterostilbene and 3′-hydroxypterostilbene are effective apoptosis-inducing agents in MDR and BCR-ABL-expressing leukemia cells
inferredcites →https://doi.org/10.1016/j.brainres.2006.03.087openalex-snapshot
Contribution of spinal glutamatergic receptors to the antinociception caused by agmatine in mice
inferredcites →https://doi.org/10.1016/j.coph.2007.03.002openalex-snapshot
Natural products as a gold mine for arthritis treatment
inferredcites →https://doi.org/10.1016/j.jpba.2006.06.035openalex-snapshot
High-performance liquid chromatographic analysis of pterostilbene in biological fluids using fluorescence detection
inferredcites →https://doi.org/10.1016/s0022-3565(25)38742-2openalex-snapshot
Antagonism of nitrous oxide antinociception in the rat hot plate test by site-specific mu and epsilon opioid receptor blockade.
inferredcites →https://doi.org/10.1016/s0024-3205(99)00410-5openalex-snapshot
Biological effects of resveratrol
inferredcites →https://doi.org/10.1016/s0031-9422(02)00108-5openalex-snapshot
Chalconoid and stilbenoid glycosides from Guibourtia tessmanii
inferredcites →https://doi.org/10.1016/s0378-8741(99)00044-6openalex-snapshot
Occurrence of resveratrol and pterostilbene in age-old darakchasava, an ayurvedic medicine from India
inferredcites →https://doi.org/10.1016/s0891-5849(02)00911-5openalex-snapshot
Inhibition of cancer growth by resveratrol is related to its low bioavailability
inferredcites →https://doi.org/10.1021/jf0009910openalex-snapshot
Stilbene Content of Mature Vitis vinifera Berries in Response to UV-C Elicitation
inferredcites →https://doi.org/10.1021/jf0116855openalex-snapshot
Cancer Chemopreventive and Antioxidant Activities of Pterostilbene, a Naturally Occurring Analogue of Resveratrol
inferredcites →https://doi.org/10.1021/jf040095eopenalex-snapshot
Resveratrol, Pterostilbene, and Piceatannol in Vaccinium Berries
inferredcites →https://doi.org/10.1021/jf0580364openalex-snapshot
Pterostilbene, a New Agonist for the Peroxisome Proliferator-Activated Receptor α-Isoform, Lowers Plasma Lipoproteins and Cholesterol in Hypercholesterolemic Hamsters
inferredcites →https://doi.org/10.1021/jf9900478openalex-snapshot
Changes in the Phytoalexin Content of Various Vitis Spp. in Response to Ultraviolet C Elicitation
inferredcites →https://doi.org/10.1021/np9607013openalex-snapshot
Antihyperglycemic Activity of Phenolics from Pterocarpus marsupium
inferredcites →https://doi.org/10.1023/a:1018943613122openalex-snapshot
Physiological Parameters in Laboratory Animals and Humans
inferredcites →https://doi.org/10.1046/j.1432-1327.2000.01606.xopenalex-snapshot
Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity
inferredcites →https://doi.org/10.1055/s-2005-864130openalex-snapshot
Selective COX-2 Inhibition by aPterocarpus marsupiumExtract Characterized by Pterostilbene, and its Activity in Healthy Human Volunteers
inferredcites →https://doi.org/10.1073/pnas.042698899openalex-snapshot
A stilbene synthase from Japanese red pine ( Pinus densiflora ): Implications for phytoalexin accumulation and down-regulation of flavonoid biosynthesis
inferredcites →https://doi.org/10.1074/jbc.m101846200openalex-snapshot
Specific Structural Determinants Are Responsible for the Antioxidant Activity and the Cell Cycle Effects of Resveratrol
inferredcites →https://doi.org/10.1111/j.1463-1326.2005.00414.xopenalex-snapshot
Pterocarpus marsupium extract (Vijayasar) prevented the alteration in metabolic patterns induced in the normal rat by feeding an adequate diet containing fructose as sole carbohydrate
inferredcites →https://doi.org/10.1124/jpet.102.033340openalex-snapshot
Metabolism and Disposition of Resveratrol in Rats: Extent of Absorption, Glucuronidation, and Enterohepatic Recirculation Evidenced by a Linked-Rat Model
inferredcites →https://doi.org/10.1152/ajpgi.00348.2005openalex-snapshot
Levels of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease: evidence for involvement of TNF-α
inferredcites →https://doi.org/10.1158/1078-0432.ccr-06-1528openalex-snapshot
Pterostilbene, an Active Constituent of Blueberries, Suppresses Aberrant Crypt Foci Formation in the Azoxymethane-Induced Colon Carcinogenesis Model in Rats
inferredcites →https://doi.org/10.1211/002235703765344522openalex-snapshot
Kinetics of metabolism and degradation of mometasone furoate in rat biological fluids and tissues
inferredcites →https://doi.org/10.1211/jpp.58.11.0004openalex-snapshot
Pharmacokinetics of selected stilbenes: rhapontigenin, piceatannol and pinosylvin in rats
inferredcites →https://doi.org/10.1248/bpb.29.2236openalex-snapshot
Evaluation of the Anti-inflammatory, Analgesic and Antipyretic Activities of the Natural Polyphenol Chlorogenic Acid
inferredcites →https://doi.org/10.1358/mf.2004.26.9.872563openalex-snapshot
Antinociceptive effect of trans-resveratrol in rats: Involvement of an opioidergic mechanism
inferredcites →https://doi.org/10.1593/neo.04337openalex-snapshot
Association between Pterostilbene and Quercetin Inhibits Metastatic Activity of B16 Melanoma
inferredcites →https://doi.org/10.2174/157488406775268246openalex-snapshot
Pharmacometrics of Stilbenes: Seguing Towards the Clinic
inferredcites →https://doi.org/10.3109/07853899708999342openalex-snapshot
Cyclo-oxygenase and Colon Cancer: Clues to the Aspirin Effect?
inferredcites →https://doi.org/10.38212/2224-6614.2755openalex-snapshot
Determination of hesperetin and its conjugate metabolites in serum and urine

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113128zenodo-depositor-declared
Stilbenes: Source plants, chemistry, biosynthesis, pharmacology, application and problems related to their clinical Application-A comprehensive review
inferred← citeshttps://doi.org/10.1002/9783527628087.ch8openalex-snapshot
Preclinic Effects of Stilbenes
inferred← citeshttps://doi.org/10.1002/advs.202412817openalex-snapshot
Nanodrugs Targeting Key Factors of Ferroptosis Regulation for Enhanced Treatment of Osteoarthritis
inferred← citeshttps://doi.org/10.1002/bdd.588openalex-snapshot
Pharmacokinetics of selected chiral flavonoids: hesperetin, naringenin and eriodictyol in rats and their content in fruit juices
inferred← citeshttps://doi.org/10.1002/biof.1410openalex-snapshot
Metabolism and pharmacokinetics of resveratrol and pterostilbene
inferred← citeshttps://doi.org/10.1002/bmc.1228openalex-snapshot
A high‐performance liquid chromatographic analysis and preliminary pharmacokinetic characterization of 3′‐hydroxypterostilbene in rats
inferred← citeshttps://doi.org/10.1002/bmc.1254openalex-snapshot
Determination of pterostilbene in rat plasma by a simple HPLC‐UV method and its application in pre‐clinical pharmacokinetic study
inferred← citeshttps://doi.org/10.1002/bmc.1320openalex-snapshot
High‐performance liquid chromatographic analysis: applications to nutraceutical content and urinary disposition of oxyresveratrol in rats
inferred← citeshttps://doi.org/10.1002/bmc.1454openalex-snapshot
Quantification of oxyresveratrol analog trans‐2,4,3′,5′‐tetramethoxystilbene in rat plasma by a rapid HPLC method: application in a pre‐clinical pharmacokinetic study
inferred← citeshttps://doi.org/10.1002/chir.20926openalex-snapshot
Stereospecific pharmacokinetics of racemic homoeriodictyol, isosakuranetin, and taxifolin in rats and their disposition in fruit
inferred← citeshttps://doi.org/10.1002/jbt.21604openalex-snapshot
Protective Effects of Pterostilbene against Acetaminophen‐Induced Hepatotoxicity in Rats
inferred← citeshttps://doi.org/10.1002/jms.1718openalex-snapshot
The assay of pterostilbene in spiked matrices by liquid chromatography tandem mass spectrometry and isotope dilution method
inferred← citeshttps://doi.org/10.1002/jps.22588openalex-snapshot
Preclinical pharmacokinetic evaluation of resveratrol trimethyl ether in sprague-dawley rats: the impacts of aqueous solubility, dose escalation, food and repeated dosing on oral bioavailability
inferred← citeshttps://doi.org/10.1002/mnfr.200800545openalex-snapshot
Inhibition of lipid peroxidation, cyclooxygenase enzyme and human tumor cell proliferation by compounds in herbal water
inferred← citeshttps://doi.org/10.1002/mnfr.201000067openalex-snapshot
Pterostilbene induces autophagy and apoptosis in sensitive and chemoresistant human bladder cancer cells
inferred← citeshttps://doi.org/10.1002/mnfr.201200651openalex-snapshot
Pharmacokinetics of pterostilbene in S prague‐ D awley rats: The impacts of aqueous solubility, fasting, dose escalation, and dosing route on bioavailability
inferred← citeshttps://doi.org/10.1002/mnfr.201400244openalex-snapshot
Pharmacokinetics and tissue distribution of pterostilbene in the rat
inferred← citeshttps://doi.org/10.1002/ptr.5363openalex-snapshot
Preclinical Pharmacokinetics and Pharmacodynamics and Content Analysis of Gnetol in Foodstuffs
inferred← citeshttps://doi.org/10.1002/rcm.4579openalex-snapshot
Structural identification of mouse urinary metabolites of pterostilbene using liquid chromatography/tandem mass spectrometry
inferred← citeshttps://doi.org/10.1007/978-3-030-39855-2_3openalex-snapshot
Pterostilbene as a Potent Chemopreventive Agent in Cancer
inferred← citeshttps://doi.org/10.1007/978-3-030-39855-2_4openalex-snapshot
Pharmacokinetics and Bioavailability Enhancement of Natural Products
inferred← citeshttps://doi.org/10.1007/978-94-007-1933-0_2openalex-snapshot
Stilbenes: Biomarkers of Grapevine Resistance to Disease of High Relevance for Agronomy, Oenology and Human Health
inferred← citeshttps://doi.org/10.1007/978-981-15-7736-9_8openalex-snapshot
Selection of Elite Genotype of a Multipurpose Forest Tree (Pterocarpus marsupium Roxb.) from Naturally Grown Populations in Central India
inferred← citeshttps://doi.org/10.1007/s00044-009-9236-2openalex-snapshot
Quantitative structure–activity relationships for estimating the aryl hydrocarbon receptor binding affinities of resveratrol derivatives and the antioxidant activities of hydroxystilbenes
inferred← citeshttps://doi.org/10.1007/s00044-018-2233-6openalex-snapshot
Effect of pterostilbene complexed with cyclodextrin on rat liver: potential reduction of oxidative damage and modulation redox-sensitive proteins
inferred← citeshttps://doi.org/10.1007/s00044-024-03212-4openalex-snapshot
Synthesis and anticancer activity of novel coumarin-stilbene hybrids with different hydrocarbon chains as linkers
inferred← citeshttps://doi.org/10.1007/s00044-026-03614-6openalex-snapshot
O-methylation of phenolic natural products: translational insights from resveratrol
inferred← citeshttps://doi.org/10.1007/s00344-018-09910-9openalex-snapshot
Meta-topolin Improves In Vitro Morphogenesis, Rhizogenesis and Biochemical Analysis in Pterocarpus marsupium Roxb.: A Potential Drug-Yielding Tree
inferred← citeshttps://doi.org/10.1007/s00709-011-0335-9openalex-snapshot
Co-expression of VpROMT gene from Chinese wild Vitis pseudoreticulata with VpSTS in tobacco plants and its effects on the accumulation of pterostilbene
inferred← citeshttps://doi.org/10.1007/s10495-011-0653-6openalex-snapshot
Pterostilbene protects vascular endothelial cells against oxidized low-density lipoprotein-induced apoptosis in vitro and in vivo
inferred← citeshttps://doi.org/10.1007/s10616-014-9758-4openalex-snapshot
Anti-proliferative effect of pterostilbene on rat hepatoma cells in culture
inferred← citeshttps://doi.org/10.1007/s10753-016-0504-2openalex-snapshot
Protective Effects of Pterostilbene Against Myocardial Ischemia/Reperfusion Injury in Rats
inferred← citeshttps://doi.org/10.1007/s10787-022-01069-wopenalex-snapshot
Pterostilbene improves CFA-induced arthritis and peripheral neuropathy through modulation of oxidative stress, inflammatory cytokines and neurotransmitters in Wistar rats
inferred← citeshttps://doi.org/10.1007/s10787-024-01440-zopenalex-snapshot
Pterostilbene: a potential therapeutic agent for fibrotic diseases
inferred← citeshttps://doi.org/10.1007/s11101-018-9578-9openalex-snapshot
A review of dietary stilbenes: sources and bioavailability
inferred← citeshttps://doi.org/10.1007/s11130-015-0479-4openalex-snapshot
Anthocyanins and Phenolic Acids of Hybrid and Native Blue Maize (Zea mays L.) Extracts and Their Antiproliferative Activity in Mammary (MCF7), Liver (HepG2), Colon (Caco2 and HT29) and Prostate (PC3) Cancer Cells
inferred← citeshttps://doi.org/10.1007/s11130-016-0556-3openalex-snapshot
Lipopolysaccharide Attenuates the Cytotoxicity of Resveratrol in Transformed Mouse Macrophages
inferred← citeshttps://doi.org/10.1007/s11240-020-01969-1openalex-snapshot
Gibberellic acid and thidiazuron promote micropropagation of an endangered woody tree (Pterocarpus marsupium Roxb.) using in vitro seedlings
inferred← citeshttps://doi.org/10.1007/s11274-020-02876-5openalex-snapshot
Natural antioxidant pterostilbene as an effective antibiofilm agent, particularly for gram-positive cocci
inferred← citeshttps://doi.org/10.1007/s11571-016-9413-1openalex-snapshot
Pterostilbene ameliorates intracerebroventricular streptozotocin induced memory decline in rats
inferred← citeshttps://doi.org/10.1007/s11605-010-1164-4openalex-snapshot
Pterostilbene Inhibits Pancreatic Cancer In Vitro
inferred← citeshttps://doi.org/10.1007/s11626-018-0308-9openalex-snapshot
Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos
inferred← citeshttps://doi.org/10.1007/s11627-020-10115-7openalex-snapshot
Direct shoot organogenesis from shoot tip explants of a highly medicinal valued tree Pterocarpus marsupium Roxb.
inferred← citeshttps://doi.org/10.1007/s13205-020-02167-8openalex-snapshot
Pterostilbene induces Nrf2/HO-1 and potentially regulates NF-κB and JNK–Akt/mTOR signaling in ischemic brain injury in neonatal rats
inferred← citeshttps://doi.org/10.1007/s13213-014-0922-zopenalex-snapshot
Pterostilbene production by microorganisms expressing resveratrol O-methyltransferase
inferred← citeshttps://doi.org/10.1016/b978-0-12-405205-5.00027-1openalex-snapshot
Pterostilbene Protection and Bladder Cancer Cells
inferred← citeshttps://doi.org/10.1016/b978-0-12-812494-9.00008-1openalex-snapshot
Epigenetic Mechanisms of Resveratrol and Its Analogs in Cancer Prevention and Treatment
inferred← citeshttps://doi.org/10.1016/b978-0-12-819547-5.00040-7openalex-snapshot
Pterostilbene and cancer chemoprevention
inferred← citeshttps://doi.org/10.1016/b978-0-12-821562-3.00033-2openalex-snapshot
Preclinical evidence of the therapeutic role of pterostilbene: Focus on the mitochondria
inferred← citeshttps://doi.org/10.1016/j.amjsurg.2009.07.014openalex-snapshot
Effects of pterostilbene on melanoma alone and in synergy with inositol hexaphosphate
inferred← citeshttps://doi.org/10.1016/j.amjsurg.2010.07.022openalex-snapshot
Pterostilbene and tamoxifen show an additive effect against breast cancer in vitro
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2020.735435openalex-snapshot
Large–scale screening of molecules involved in virus–host interaction by specific compounds in Cherax quadricarinatus hematopoietic tissue cells
inferred← citeshttps://doi.org/10.1016/j.arr.2023.102125openalex-snapshot
Unlocking the therapeutic potential of natural stilbene: Exploring pterostilbene as a powerful ally against aging and cognitive decline
inferred← citeshttps://doi.org/10.1016/j.bbrc.2024.150358openalex-snapshot
Pterostilbene alleviates MPTP-induced neurotoxicity by targeting neuroinflammation and oxidative stress
inferred← citeshttps://doi.org/10.1016/j.bcp.2020.113792openalex-snapshot
Small molecule inhibitors and stimulators of inducible nitric oxide synthase in cancer cells from natural origin (phytochemicals, marine compounds, antibiotics)
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.103073openalex-snapshot
The stilbene derivatives, nucleosides, and nucleosides modified by stilbene derivatives
inferred← citeshttps://doi.org/10.1016/j.biopha.2019.109781openalex-snapshot
The stilbene and dibenzo[b,f]oxepine derivatives as anticancer compounds
inferred← citeshttps://doi.org/10.1016/j.blre.2018.07.001openalex-snapshot
Rationale for assessing the therapeutic potential of resveratrol in hematological malignancies
inferred← citeshttps://doi.org/10.1016/j.bmc.2017.01.010openalex-snapshot
Design, synthesis and evaluation of some N-methylenebenzenamine derivatives as selective acetylcholinesterase (AChE) inhibitor and antioxidant to enhance learning and memory
inferred← citeshttps://doi.org/10.1016/j.bmcl.2013.12.115openalex-snapshot
Urokinase-type plasminogen activator expression and Rac1/WAVE-2/Arp2/3 pathway are blocked by pterostilbene to suppress cell migration and invasion in MDA-MB-231 cells
inferred← citeshttps://doi.org/10.1016/j.cbi.2013.09.013openalex-snapshot
Scavenging of hydroxyl radical by resveratrol and related natural stilbenes after hydrogen peroxide attack on DNA
inferred← citeshttps://doi.org/10.1016/j.chmed.2022.08.004openalex-snapshot
Pterostilbene supresses inflammation-induced melanoma metastasis by impeding neutrophil elastase-mediated thrombospondin-1 degradation
inferred← citeshttps://doi.org/10.1016/j.drudis.2010.07.005openalex-snapshot
Resveratrol and derivatives for the prevention and treatment of cancer
inferred← citeshttps://doi.org/10.1016/j.ejphar.2016.07.046openalex-snapshot
Promising therapeutic potential of pterostilbene and its mechanistic insight based on preclinical evidence
inferred← citeshttps://doi.org/10.1016/j.eng.2025.04.026openalex-snapshot
Prebiotic Microcapsule-Encapsulated Pterostilbene Alleviates Ulcerative Colitis by Regulating the Intestinal Microenvironment and Activating AHR/IL-22 Pathway
inferred← citeshttps://doi.org/10.1016/j.fct.2008.11.038openalex-snapshot
Pterostilbene from Vitis coignetiae protect H2O2-induced inhibition of gap junctional intercellular communication in rat liver cell line
inferred← citeshttps://doi.org/10.1016/j.fct.2016.11.007openalex-snapshot
Enhanced chemoprevention by the combined treatment of pterostilbene and lupeol in B[a]P-induced mouse skin tumorigenesis
inferred← citeshttps://doi.org/10.1016/j.fct.2018.12.012openalex-snapshot
RETRACTED: Pterostilbene protects against acetaminophen-induced liver injury by restoring impaired autophagic flux
inferred← citeshttps://doi.org/10.1016/j.fitote.2015.07.009openalex-snapshot
Effect of substituted stilbenes on platelet function
inferred← citeshttps://doi.org/10.1016/j.foodchem.2012.11.094openalex-snapshot
Pterostilbene inhibits dimethylnitrosamine-induced liver fibrosis in rats
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2015.02.029openalex-snapshot
Pterostilbene and allopurinol reduce fructose-induced podocyte oxidative stress and inflammation via microRNA-377
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2015.03.027openalex-snapshot
Topical treatment with pterostilbene, a natural phytoalexin, effectively protects hairless mice against UVB radiation-induced skin damage and carcinogenesis
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2021.11.041openalex-snapshot
Alginate with citrus pectin and pterostilbene as healthy food packaging with antioxidant property
inferred← citeshttps://doi.org/10.1016/j.ijdevneu.2016.08.005openalex-snapshot
Neuroprotective actions of pterostilbene on hypoxic‐ischemic brain damage in neonatal rats through upregulation of heme oxygenase‐1
inferred← citeshttps://doi.org/10.1016/j.ijfoodmicro.2012.12.018openalex-snapshot
Growth inhibitory effect of grape phenolics against wine spoilage yeasts and acetic acid bacteria
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2018.12.050openalex-snapshot
Enzyme nanovehicles: Histaminase and catalase delivered in nanoparticulate chitosan
inferred← citeshttps://doi.org/10.1016/j.indcrop.2023.116681openalex-snapshot
Micropropagation of Pterocarpus marsupium Roxb. through synthetic seeds and its novel antibiofilm activities against ESKAPE pathogens
inferred← citeshttps://doi.org/10.1016/j.intimp.2015.05.003openalex-snapshot
Understanding the mode of action of a pterostilbene derivative as anti-inflammatory agent
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.111198openalex-snapshot
The pterostilbene-dihydropyrazole derivative Ptd-1 ameliorates vascular calcification by regulating inflammation
inferred← citeshttps://doi.org/10.1016/j.jchromb.2011.03.025openalex-snapshot
Development of a reversed phase high performance liquid chromatography method based on the use of cyclodextrins as mobile phase additives to determine pterostilbene in blueberries
inferred← citeshttps://doi.org/10.1016/j.jecm.2011.10.001openalex-snapshot
Molecular Mechanisms of Nicotine-induced Bladder Cancer
inferred← citeshttps://doi.org/10.1016/j.jep.2011.03.025openalex-snapshot
Evaluation of antinociceptive effect of Aegiceras corniculatum stems extracts and its possible mechanism of action in rodents
inferred← citeshttps://doi.org/10.1016/j.jep.2023.117385openalex-snapshot
Ethnopharmacologically important highly subsidized Indian medicinal plants: Systematic review on their traditional uses, phytochemistry, pharmacology, quality control, conservation status and future prospective
inferred← citeshttps://doi.org/10.1016/j.jfda.2016.07.004openalex-snapshot
Biological actions and molecular effects of resveratrol, pterostilbene, and 3′-hydroxypterostilbene
inferred← citeshttps://doi.org/10.1016/j.jff.2014.10.018openalex-snapshot
Pterostilbene surpassed resveratrol for anti-inflammatory application: Potency consideration and pharmacokinetics perspective
inferred← citeshttps://doi.org/10.1016/j.jff.2015.12.030openalex-snapshot
Resveratrol and pterostilbene ameliorate the metabolic derangements associated with smokeless tobacco in estrogen deficient female rats
inferred← citeshttps://doi.org/10.1016/j.jff.2016.01.020openalex-snapshot
Oxyresveratrol: A bioavailable dietary polyphenol
inferred← citeshttps://doi.org/10.1016/j.jff.2017.11.003openalex-snapshot
Pterostilbene inhibited advanced glycation end products (AGEs)-induced oxidative stress and inflammation by regulation of RAGE/MAPK/NF-κB in RAW264.7 cells
inferred← citeshttps://doi.org/10.1016/j.jff.2020.104275openalex-snapshot
Pterostilbene attenuates ischemic stroke by modulating miR-21-5p/PDCD4 axis in vivo and in vitro
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2012.06.008openalex-snapshot
Pterostilbene, a natural small-molecular compound, promotes cytoprotective macroautophagy in vascular endothelial cells
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2014.11.015openalex-snapshot
Pterostilbene suppressed irradiation-resistant glioma stem cells by modulating GRP78/miR-205 axis
inferred← citeshttps://doi.org/10.1016/j.jpba.2010.10.028openalex-snapshot
High-performance liquid chromatography assay of gnetol in rat serum and application to pre-clinical pharmacokinetic studies
inferred← citeshttps://doi.org/10.1016/j.jpba.2011.08.020openalex-snapshot
Determination of trans-2,4,3′,4′,5′-pentamethoxystilbene in rat plasma and its application to a pharmacokinetic study
inferred← citeshttps://doi.org/10.1016/j.jpba.2015.04.045openalex-snapshot
UPLC–MS method for quantification of pterostilbene and its application to comparative study of bioavailability and tissue distribution in normal and Lewis lung carcinoma bearing mice
inferred← citeshttps://doi.org/10.1016/j.jpha.2024.101043openalex-snapshot
Pterostilbene: A natural neuroprotective stilbene with anti-Alzheimer's disease properties
inferred← citeshttps://doi.org/10.1016/j.jphotobiol.2015.05.001openalex-snapshot
Spectroscopic study on the interaction of resveratrol and pterostilbene with human serum albumin
inferred← citeshttps://doi.org/10.1016/j.jss.2009.06.027openalex-snapshot
Pterostilbene Inhibits Lung Cancer Through Induction of Apoptosis
inferred← citeshttps://doi.org/10.1016/j.jss.2009.07.027openalex-snapshot
Pterostilbene Inhibits Breast Cancer In Vitro Through Mitochondrial Depolarization and Induction of Caspase-Dependent Apoptosis
inferred← citeshttps://doi.org/10.1016/j.jss.2011.09.054openalex-snapshot
Pterostilbene and Cancer: Current Review
inferred← citeshttps://doi.org/10.1016/j.micpath.2020.104632openalex-snapshot
Antibiofilm agent pterostilbene is able to enhance antibiotics action against Staphylococcus epidermidis
inferred← citeshttps://doi.org/10.1016/j.molliq.2021.115700openalex-snapshot
Solubility data, Hansen solubility parameters and thermodynamic behavior of pterostilbene in some pure solvents and different (PEG-400 + water) cosolvent compositions
inferred← citeshttps://doi.org/10.1016/j.nbt.2018.02.011openalex-snapshot
Rosa hybrida orcinol O-methyl transferase-mediated production of pterostilbene in metabolically engineered grapevine cell cultures
inferred← citeshttps://doi.org/10.1016/j.neurobiolaging.2011.08.015openalex-snapshot
Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.nutres.2016.11.010openalex-snapshot
Intake of bilberries (Vaccinium myrtillus L.) reduced risk factors for cardiovascular disease by inducing favorable changes in lipoprotein profiles
inferred← citeshttps://doi.org/10.1016/j.oraloncology.2015.03.007openalex-snapshot
Pterostilbene induce autophagy on human oral cancer cells through modulation of Akt and mitogen-activated protein kinase pathway
inferred← citeshttps://doi.org/10.1016/j.pbb.2015.06.009openalex-snapshot
Orally administrated pterostilbene attenuates acute cerebral ischemia–reperfusion injury in a dose- and time-dependent manner in mice
inferred← citeshttps://doi.org/10.1016/j.phymed.2026.158689openalex-snapshot
Pterostilbene promotes placental angiogenesis in pregnant sows via epigenetic regulation of the miR-369/Nrf2/HIF-1α signaling axis
inferred← citeshttps://doi.org/10.1016/j.phyplu.2022.100311openalex-snapshot
Evaluation of hepatoprotective activity of ethanolic extract of Pterocarpus marsupium Roxb. leaves against paracetamol-induced liver damage via reduction of oxidative stress
inferred← citeshttps://doi.org/10.1016/j.phytochem.2010.10.009openalex-snapshot
Kinetic mechanism and product characterization of the enzymatic peroxidation of pterostilbene as model of the detoxification process of stilbene-type phytoalexins
inferred← citeshttps://doi.org/10.1016/j.phytol.2025.03.001openalex-snapshot
Chemopreventive properties of naturally occurring methoxylated resveratrol analogues
inferred← citeshttps://doi.org/10.1016/j.pnpbp.2014.03.015openalex-snapshot
Pterostilbene attenuates lipopolysaccharide-induced learning and memory impairment possibly via inhibiting microglia activation and protecting neuronal injury in mice
inferred← citeshttps://doi.org/10.1016/j.prenap.2025.100173openalex-snapshot
Stilbenes in breast cancer treatment: Nanostilbenes an approach to improve therapeutic efficacy
inferred← citeshttps://doi.org/10.1016/j.semcancer.2020.02.012openalex-snapshot
Metastasis-associated protein 1-mediated antitumor and anticancer activity of dietary stilbenes for prostate cancer chemoprevention and therapy
inferred← citeshttps://doi.org/10.1016/j.sjbs.2023.103717openalex-snapshot
Pterostilbene induces apoptosis in hepatocellular carcinoma cells: Biochemical, pathological, and molecular markers
inferred← citeshttps://doi.org/10.1016/j.snb.2016.03.113openalex-snapshot
Electrochemical determination of pterostilbene at a cathodically pretreated boron-doped diamond electrode using square-wave adsorptive anodic stripping voltammetry in cationic surfactant media
inferred← citeshttps://doi.org/10.1016/j.taap.2014.03.011openalex-snapshot
α-Dihydroxychalcone-glycoside (α-DHC) isolated from the heartwood of Pterocarpus marsupium inhibits LPS induced MAPK activation and up regulates HO-1 expression in murine RAW 264.7 macrophage
inferred← citeshttps://doi.org/10.1016/j.tifs.2019.07.042openalex-snapshot
Plants of the genus Vitis: Phenolic compounds, anticancer properties and clinical relevance
inferred← citeshttps://doi.org/10.1016/j.toxicon.2020.11.002openalex-snapshot
Pterostilbene inhibits deoxynivalenol-induced oxidative stress and inflammatory response in bovine mammary epithelial cells
inferred← citeshttps://doi.org/10.1016/j.vph.2010.04.001openalex-snapshot
Pterostilbene, a natural dimethylated analog of resveratrol, inhibits rat aortic vascular smooth muscle cell proliferation by blocking Akt-dependent pathway
inferred← citeshttps://doi.org/10.1016/j.ymthe.2023.02.017openalex-snapshot
Reactive oxygen species-responsive nanocarrier ameliorates murine colitis by intervening colonic innate and adaptive immune responses
inferred← citeshttps://doi.org/10.1021/acs.jafc.0c00070openalex-snapshot
Chemistry of Pterostilbene and Its Metabolic Effects
inferred← citeshttps://doi.org/10.1021/acs.jafc.0c00498openalex-snapshot
Effects of Selected Resveratrol Analogues on Activation and Polarization of Lipopolysaccharide-Stimulated BV-2 Microglial Cells
inferred← citeshttps://doi.org/10.1021/acs.jafc.2c05334openalex-snapshot
Phase I Metabolism of Pterostilbene, a Dietary Resveratrol Derivative: Metabolite Identification, Species Differences, Isozyme Contribution, and Further Bioactivation
inferred← citeshttps://doi.org/10.1021/acs.jafc.7b03712openalex-snapshot
3′-Hydroxypterostilbene Suppresses Colitis-Associated Tumorigenesis by Inhibition of IL-6/STAT3 Signaling in Mice
inferred← citeshttps://doi.org/10.1021/acs.jafc.9b07147openalex-snapshot
Neuroprotective and Anti-inflammatory Effects of Pterostilbene Metabolites in Human Neuroblastoma SH-SY5Y and RAW 264.7 Macrophage Cells
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.3c01698openalex-snapshot
Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6b01203openalex-snapshot
Tackling Fungal Resistance by Biofilm Inhibitors
inferred← citeshttps://doi.org/10.1021/acs.orglett.9b01200openalex-snapshot
Catalytic Selective Oxidative Coupling of Secondary N-Alkylanilines: An Approach to Azoxyarene
inferred← citeshttps://doi.org/10.1021/jacs.5c08094openalex-snapshot
Probiotic–Drug Conjugates Achieve Synchronized Site-Specific Probiotic Colonization and On-Demand Drug Release against Ulcerative Colitis and Its Complication
inferred← citeshttps://doi.org/10.1021/jf101571zopenalex-snapshot
Pterostilbene Inhibits Colorectal Aberrant Crypt Foci (ACF) and Colon Carcinogenesis via Suppression of Multiple Signal Transduction Pathways in Azoxymethane-Treated Mice
inferred← citeshttps://doi.org/10.1021/jf202426kopenalex-snapshot
Resveratrol Modulates MED28 (Magicin/EG-1) Expression and Inhibits Epidermal Growth Factor (EGF)-Induced Migration in MDA-MB-231 Human Breast Cancer Cells
inferred← citeshttps://doi.org/10.1021/jf301499eopenalex-snapshot
Activation of AMPK by Pterostilbene Suppresses Lipogenesis and Cell-Cycle Progression in p53 Positive and Negative Human Prostate Cancer Cells
inferred← citeshttps://doi.org/10.1021/jf302778aopenalex-snapshot
Chemopreventive Effects of Pterostilbene on Urethane-Induced Lung Carcinogenesis in Mice via the Inhibition of EGFR-Mediated Pathways and the Induction of Apoptosis and Autophagy
inferred← citeshttps://doi.org/10.1021/jf400342gopenalex-snapshot
Stilbenes and Anthocyanins Reduce Stress Signaling in BV-2 Mouse Microglia
inferred← citeshttps://doi.org/10.1021/jf800820yopenalex-snapshot
Pterostilbene Suppressed Lipopolysaccharide-Induced Up-Expression of iNOS and COX-2 in Murine Macrophages
inferred← citeshttps://doi.org/10.1021/jf802279hopenalex-snapshot
Cellular and Behavioral Effects of Stilbene Resveratrol Analogues: Implications for Reducing the Deleterious Effects of Aging
inferred← citeshttps://doi.org/10.1021/jf803579eopenalex-snapshot
Dietary Administration of High Doses of Pterostilbene and Quercetin to Mice Is Not Toxic
inferred← citeshttps://doi.org/10.1021/jf900285eopenalex-snapshot
Physicochemical Study of the Complexation of Pterostilbene by Natural and Modified Cyclodextrins
inferred← citeshttps://doi.org/10.1021/ol503065aopenalex-snapshot
MIDA–Vinylsilanes: Selective Cross-Couplings and Applications to the Synthesis of Functionalized Stilbenes
inferred← citeshttps://doi.org/10.1038/cddis.2017.333openalex-snapshot
P53-dependent downregulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatment
inferred← citeshttps://doi.org/10.1038/s41598-021-85908-wopenalex-snapshot
Pterostilbene promotes mitochondrial apoptosis and inhibits proliferation in glioma cells
inferred← citeshttps://doi.org/10.1038/srep19408openalex-snapshot
Blueberry Component Pterostilbene Protects Corneal Epithelial Cells from Inflammation via Anti-oxidative Pathway
inferred← citeshttps://doi.org/10.1038/srep36827openalex-snapshot
Engineering yeast for high-level production of stilbenoid antioxidants
inferred← citeshttps://doi.org/10.1038/srep37417openalex-snapshot
Pterostilbene induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma cells
inferred← citeshttps://doi.org/10.1039/b801558aopenalex-snapshot
Chemopreventive effects of natural dietary compounds on cancer development
inferred← citeshttps://doi.org/10.1039/c5ra06107eopenalex-snapshot
Aryl alkyl carbene–Pd complex assisted C–Cl bond activation: an unprecedented cross-coupling route to trans-stilbenes
inferred← citeshttps://doi.org/10.1039/c6ra28832dopenalex-snapshot
Podophyllotoxin–pterostilbene fused conjugates as potential multifunctional antineoplastic agents against human uveal melanoma cells
inferred← citeshttps://doi.org/10.1039/c9fo01405eopenalex-snapshot
Protective effect of pterostilbene on concanavalin A-induced acute liver injury
inferred← citeshttps://doi.org/10.1039/d3fo01235bopenalex-snapshot
Pterostilbene alleviates abdominal aortic aneurysm via inhibiting macrophage pyroptosis by activating the miR-146a-5p/TRAF6 axis
inferred← citeshttps://doi.org/10.1039/d4fo06413eopenalex-snapshot
Pterostilbene attenuates intestinal barrier damage and secondary liver oxidative stress in a murine model of Clostridium difficile infection by regulating the gut microbiota
inferred← citeshttps://doi.org/10.1055/s-0028-1088301openalex-snapshot
Biological/Chemopreventive Activity of Stilbenes and their Effect on Colon Cancer
inferred← citeshttps://doi.org/10.1055/s-0032-1328553openalex-snapshot
Anxiolytic Action of Pterostilbene: Involvement of Hippocampal ERK Phosphorylation
inferred← citeshttps://doi.org/10.1080/01480545.2022.2042014openalex-snapshot
Subacute oral toxicology and toxicokinetics of pterostilbene, a novel Top1/Tdp1 inhibiting anti-tumor reagent
inferred← citeshttps://doi.org/10.1080/01635581.2024.2364391openalex-snapshot
Natural Stilbenes: Their Role in Colorectal Cancer Prevention, DNA Methylation, and Therapy
inferred← citeshttps://doi.org/10.1080/0886022x.2025.2538798openalex-snapshot
Mechanisms of NLRP3 inflammasome in chronic kidney disease and the effects of traditional Chinese medicines
inferred← citeshttps://doi.org/10.1080/09168451.2016.1240606openalex-snapshot
Synthesis, oxygen radical absorbance capacity, and tyrosinase inhibitory activity of glycosides of resveratrol, pterostilbene, and pinostilbene
inferred← citeshttps://doi.org/10.1080/10408398.2011.582544openalex-snapshot
Cyclodextrins and Antioxidants
inferred← citeshttps://doi.org/10.1080/10715762.2019.1635252openalex-snapshot
Pterostilbene reverses palmitic acid mediated insulin resistance in HepG2 cells by reducing oxidative stress and triglyceride accumulation
inferred← citeshttps://doi.org/10.1080/14656566.2023.2269090openalex-snapshot
Recent advances in drug treatments for dry eye disease
inferred← citeshttps://doi.org/10.1089/jmf.2019.4647openalex-snapshot
Pterostilbene Protects Against Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure by Upregulating the Nrf2 Pathway and Inhibiting NF- κ B, MAPK, and NLRP3 Inflammasome Activation
inferred← citeshttps://doi.org/10.1089/jmf.2020.4766openalex-snapshot
Pterostilbene Improves Stress-Related Behaviors and Partially Reverses Underlying Neuroinflammatory and Hormonal Changes in Stress-Challenged Mice
inferred← citeshttps://doi.org/10.1093/abbs/gmy070openalex-snapshot
Targeting the PI3K/Akt/mTOR signaling pathway by pterostilbene attenuates mantle cell lymphoma progression
inferred← citeshttps://doi.org/10.1093/carcin/bgp121openalex-snapshot
Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells
inferred← citeshttps://doi.org/10.1093/toxsci/kft238openalex-snapshot
A Combination of Pterostilbene With Autophagy Inhibitors Exerts Efficient Apoptotic Characteristics in Both Chemosensitive and Chemoresistant Lung Cancer Cells
inferred← citeshttps://doi.org/10.1111/1750-3841.13002openalex-snapshot
Pterostilbene Inhibits Vascular Smooth Muscle Cells Migration and Matrix Metalloproteinase‐2 through Modulation of MAPK Pathway
inferred← citeshttps://doi.org/10.1111/imm.13469openalex-snapshot
Targeting glycolysis in Th2 cells by pterostilbene attenuates clinical severities in an asthmatic mouse model and IL‐4 production in peripheral blood from asthmatic patients
inferred← citeshttps://doi.org/10.1111/j.1467-7652.2011.00657.xopenalex-snapshot
In planta production of the highly potent resveratrol analogue pterostilbene via stilbene synthase and O‐methyltransferase co‐expression
inferred← citeshttps://doi.org/10.1111/nyas.13450openalex-snapshot
Gnetin‐C and other resveratrol oligomers with cancer chemopreventive potential
inferred← citeshttps://doi.org/10.1111/pbi.12539openalex-snapshot
Production of highly bioactive resveratrol analogues pterostilbene and piceatannol in metabolically engineered grapevine cell cultures
inferred← citeshttps://doi.org/10.1111/php.13704openalex-snapshot
Singlet Oxygen Quenching by Resveratrol Derivatives †
inferred← citeshttps://doi.org/10.1128/aac.01583-13openalex-snapshot
In Vitro and In Vivo Activities of Pterostilbene against Candida albicans Biofilms
inferred← citeshttps://doi.org/10.1155/2013/106041openalex-snapshot
The Effects of Pterostilbene on Neutrophil Activity in Experimental Model of Arthritis
inferred← citeshttps://doi.org/10.1155/2013/258425openalex-snapshot
BlueBerry Isolate, Pterostilbene, Functions as a Potential Anticancer Stem Cell Agent in Suppressing Irradiation-Mediated Enrichment of Hepatoma Stem Cells
inferred← citeshttps://doi.org/10.1155/2013/261468openalex-snapshot
Pharmacometrics of 3-Methoxypterostilbene: A Component of Traditional Chinese Medicinal Plants
inferred← citeshttps://doi.org/10.1155/2013/463595openalex-snapshot
Analysis of Safety from a Human Clinical Trial with Pterostilbene
inferred← citeshttps://doi.org/10.1155/2013/575482openalex-snapshot
A Review of Pterostilbene Antioxidant Activity and Disease Modification
inferred← citeshttps://doi.org/10.1155/2014/320895openalex-snapshot
Cytotoxicity Studies of Novel Combretastatin and Pterostilbene Derivatives
inferred← citeshttps://doi.org/10.1155/2016/3128951openalex-snapshot
Role of Natural Stilbenes in the Prevention of Cancer
inferred← citeshttps://doi.org/10.1155/2017/9872073openalex-snapshot
Pterostilbene Induces Cell Apoptosis and Cell Cycle Arrest in T-Cell Leukemia/Lymphoma by Suppressing the ERK1/2 Pathway
inferred← citeshttps://doi.org/10.1155/2018/2747018openalex-snapshot
Pterostilbene 4 ′‐β‐Glucoside Attenuates LPS‐Induced Acute Lung Injury via Induction of Heme Oxygenase‐1
inferred← citeshttps://doi.org/10.1155/2019/1243215openalex-snapshot
Pterostilbene Attenuates Fructose-Induced Myocardial Fibrosis by Inhibiting ROS-Driven Pitx2c/miR-15b Pathway
inferred← citeshttps://doi.org/10.1155/2019/8361858openalex-snapshot
Selectivity of Dietary Phenolics for Inhibition of Human Monoamine Oxidases A and B
inferred← citeshttps://doi.org/10.1155/2021/2951697openalex-snapshot
A Systematic Review of the Potential Chemoprotective Effects of Resveratrol on Doxorubicin‐Induced Cardiotoxicity: Focus on the Antioxidant, Antiapoptotic, and Anti‐Inflammatory Activities
inferred← citeshttps://doi.org/10.1155/2023/6657869openalex-snapshot
The Effects of Antioxidants and Pulsed Magnetic Fields on Slow and Fast Skeletal Muscle Atrophy Induced by Streptozotocin: A Preclinical Study
inferred← citeshttps://doi.org/10.1158/1940-6207.capr-08-0224openalex-snapshot
Anti-inflammatory Action of Pterostilbene Is Mediated through the p38 Mitogen-Activated Protein Kinase Pathway in Colon Cancer Cells
inferred← citeshttps://doi.org/10.1177/1934578x261471414openalex-snapshot
Chemical Ingredients and Antitumor Application of Dragon’s Blood
inferred← citeshttps://doi.org/10.1186/1471-2210-8-15openalex-snapshot
Methoxylation enhances stilbene bioactivity in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1186/1472-6882-13-238openalex-snapshot
Protective effect of Pterostilbene against free radical mediated oxidative damage
inferred← citeshttps://doi.org/10.1186/1476-511x-11-76openalex-snapshot
Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor
inferred← citeshttps://doi.org/10.1186/s12934-017-0644-6openalex-snapshot
De novo biosynthesis of pterostilbene in an Escherichia coli strain using a new resveratrol O-methyltransferase from Arabidopsis
inferred← citeshttps://doi.org/10.1186/s12934-019-1118-9openalex-snapshot
High-yield production of multiple O-methylated phenylpropanoids by the engineered Escherichia coli–Streptomyces cocultivation system
inferred← citeshttps://doi.org/10.1186/s12935-021-02099-0openalex-snapshot
Therapeutic potentials of resveratrol in combination with radiotherapy and chemotherapy during glioblastoma treatment: a mechanistic review
inferred← citeshttps://doi.org/10.1186/s12951-021-00928-yopenalex-snapshot
Nanoparticles prepared from pterostilbene reduce blood glucose and improve diabetes complications
inferred← citeshttps://doi.org/10.1186/s12985-022-01954-4openalex-snapshot
Suppressive effects of pterostilbene on human cytomegalovirus (HCMV) infection and HCMV-induced cellular senescence
inferred← citeshttps://doi.org/10.1186/s13765-021-00607-4openalex-snapshot
Biosynthesis of resveratrol derivatives and evaluation of their anti-inflammatory activity
inferred← citeshttps://doi.org/10.1186/s40104-020-00460-3openalex-snapshot
Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets
inferred← citeshttps://doi.org/10.1262/jrd.2018-089openalex-snapshot
Pterostilbene alleviates hydrogen peroxide-induced oxidative stress via nuclear factor erythroid 2 like 2 pathway in mouse preimplantation embryos
inferred← citeshttps://doi.org/10.13005/bpj/2290openalex-snapshot
Assessment of Skin Irritation and Sensitisation Effects by Topical Pterostilbene
inferred← citeshttps://doi.org/10.1365/s10337-010-1727-2openalex-snapshot
LC Determination of trans-3,5,3′,4′,5′-Pentamethoxystilbene in Rat Plasma
inferred← citeshttps://doi.org/10.1371/journal.pone.0057542openalex-snapshot
Pterostilbene Acts through Metastasis-Associated Protein 1 to Inhibit Tumor Growth, Progression and Metastasis in Prostate Cancer
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