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In vivo Antimalarial Activity of α‐Mangostin and the New Xanthone δ‐Mangostin

https://doi.org/10.1002/ptr.5362
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Pharmacokinetics of α‐mangostin in rats after intravenous and oral application
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Garcinia mangostana L.: a phytochemical and pharmacological review
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New “hyphenated” CPC-HPLC-DAD-MS strategy for simultaneous isolation, analysis and identification of phytochemicals: application to xanthones from Garcinia mangostana
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An efficient synthesis of new caffeine-based chalcones, pyrazolines and pyrazolo[3,4-b][1,4]diazepines as potential antimalarial, antitrypanosomal and antileishmanial agents
inferredcites →https://doi.org/10.1016/j.fct.2008.07.024openalex-snapshot
Medicinal properties of mangosteen (Garcinia mangostana)
inferredcites →https://doi.org/10.1016/j.foodchem.2006.11.018openalex-snapshot
Phenolics from hull of Garcinia mangostana fruit and their antioxidant activities
inferredcites →https://doi.org/10.1016/j.jep.2010.10.039openalex-snapshot
Plants used by native Amazonian groups from the Nanay River (Peru) for the treatment of malaria
inferredcites →https://doi.org/10.1016/j.jep.2012.04.045openalex-snapshot
Genotoxicity assessment of Garcinia achachairu Rusby (Clusiaceae) extract in mammalian cells in vivo
inferredcites →https://doi.org/10.1016/j.lfs.2004.07.009openalex-snapshot
Antimalarial xanthones from Calophyllum caledonicum and Garcinia vieillardii
inferredcites →https://doi.org/10.1016/j.peptides.2006.08.005openalex-snapshot
Isolation and biochemical characterization of peptides presenting antimicrobial activity from the skin of Phyllomedusa hypochondrialis
inferredcites →https://doi.org/10.1016/j.seppur.2011.04.027openalex-snapshot
Xanthones enriched extracts from mangosteen pericarp obtained by supercritical carbon dioxide process
inferredcites →https://doi.org/10.1016/s0140-6736(12)60034-8openalex-snapshot
Global malaria mortality between 1980 and 2010: a systematic analysis
inferredcites →https://doi.org/10.1021/np100737qopenalex-snapshot
Phenolic Glycosides with Antimalarial Activity from Grevillea “Poorinda Queen”
inferredcites →https://doi.org/10.1021/np8000255openalex-snapshot
Xanthones from the Botanical Dietary Supplement Mangosteen (Garcinia mangostana) with Aromatase Inhibitory Activity
inferredcites →https://doi.org/10.1021/np900517hopenalex-snapshot
Cytotoxic Xanthone Constituents of the Stem Bark of Garcinia mangostana (Mangosteen)
inferredcites →https://doi.org/10.1080/00034983.1970.11686683openalex-snapshot
The antimalarial activity of some quinolone esters
inferredcites →https://doi.org/10.1080/13880200600885234openalex-snapshot
Antiprotozoal Activity AgainstPlasmodium falciparum. andTrypanosoma cruzi. of Xanthones Isolated fromChrysochlamys tenuis.
inferredcites →https://doi.org/10.1126/science.318.5850.560openalex-snapshot
Malaria Treatment: ACT Two
inferredcites →https://doi.org/10.1126/science.781840openalex-snapshot
Human Malaria Parasites in Continuous Culture
inferredcites →https://doi.org/10.1128/aac.00671-11openalex-snapshot
In Vitro and In Vivo Studies of the Utility of Dimethyl and Diethyl Carbaporphyrin Ketals in Treatment of Cutaneous Leishmaniasis
inferredcites →https://doi.org/10.1128/aac.49.4.1652-1655.2005openalex-snapshot
In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives
inferredcites →https://doi.org/10.1179/000349803225002390openalex-snapshot
In-vivo antimalarial activity of some oxygenated xanthones
inferredcites →https://doi.org/10.2174/092986705774370709openalex-snapshot
Xanthones as Antimalarial Agents: Discovery, Mode of Action, and Optimization
inferredcites →https://doi.org/10.2174/156652411797536679openalex-snapshot
Xanthones from Mangosteen Extracts as Natural Chemopreventive Agents: Potential Anticancer Drugs
inferredcites →https://doi.org/10.2307/2982559openalex-snapshot
Statistical Method in Biological Assay.
inferredcites →https://doi.org/10.3390/molecules18044718openalex-snapshot
New Amide Derivatives of Quinoxaline 1,4-di-N-Oxide with Leishmanicidal and Antiplasmodial Activities
inferredcites →https://doi.org/10.3390/molecules180910599openalex-snapshot
Phytochemical, Antimicrobial and Antiprotozoal Evaluation of Garcinia Mangostana Pericarp and α-Mangostin, Its Major Xanthone Derivative
inferredcites →https://doi.org/10.3390/nu5083163openalex-snapshot
Biological Activities and Bioavailability of Mangosteen Xanthones: A Critical Review of the Current Evidence
inferredcites →https://doi.org/10.7883/yoken.65.465openalex-snapshot
Evolution of Plasmodium falciparum drug resistance: implications for the development and containment of artemisinin resistance

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4637912openalex-extracted
In-Silico Studies of Hydroxyxanthone Derivatives as Potential pfDHFR and pfDHODH Inhibitor by Molecular Docking, Molecular Dynamics Simulation, MM-PBSA Calculation and Pharmacokinetic Analysis
inferred← citeshttps://doi.org/10.1002/9781119158042.ch9openalex-snapshot
Mangosteen Xanthones: Bioavailability and Bioactivities
inferred← citeshttps://doi.org/10.1002/9783527830589.ch9openalex-snapshot
Natural Products as a Source for Antimalarial Drug Development Process – An Overview
inferred← citeshttps://doi.org/10.1002/ptr.6077openalex-snapshot
Combination of artemisinin‐based natural compounds from Artemisia annua L. for the treatment of malaria: Pharmacodynamic and pharmacokinetic studies
inferred← citeshttps://doi.org/10.1002/ptr.6768openalex-snapshot
Investigating the ameliorative effect of alpha‐mangostin on development and existing pain in a rat model of neuropathic pain
inferred← citeshttps://doi.org/10.1007/s10600-021-03338-6openalex-snapshot
Two New γ-Mangostin Glycosides Through Microbial Transformation by Cunninghamella blakesleana
inferred← citeshttps://doi.org/10.1007/s11172-025-4837-6openalex-snapshot
Chemical modification of natural xanthones, α- and γ-mangostins, and potential of their derivatives as biologically active compounds
inferred← citeshttps://doi.org/10.1007/s11224-019-01333-wopenalex-snapshot
Relationship between electronic structures and antiplasmodial activities of xanthone derivatives: a 2D-QSAR approach
inferred← citeshttps://doi.org/10.1007/s13659-025-00528-5openalex-snapshot
Exploring the antineoplastic potential of α-mangostin in breast cancer
inferred← citeshttps://doi.org/10.1007/s43450-024-00571-2openalex-snapshot
Plasmodium falciparum Lactate Dehydrogenase Inhibitory Activities of Pomegranate and Mangosteen Extracts and their Major Constituents
inferred← citeshttps://doi.org/10.1007/s44371-026-00981-2openalex-snapshot
Comprehensive review on applications of Garcinia mangostana
inferred← citeshttps://doi.org/10.1016/b978-0-12-816811-0.00001-9openalex-snapshot
Antiparasitic Asian medicinal plants in the Clade Protomagnoliids
inferred← citeshttps://doi.org/10.1016/b978-0-12-816811-0.00007-xopenalex-snapshot
Antiparasitic Asian medicinal plants in the Clade Fabids
inferred← citeshttps://doi.org/10.1016/b978-0-323-91942-5.00009-4openalex-snapshot
Natural products employed in the management of malaria
inferred← citeshttps://doi.org/10.1016/j.actatropica.2024.107291openalex-snapshot
Computational and experimental approaches manifest the leishmanicidal potential of α-mangostin resourced from Garcinia cowa
inferred← citeshttps://doi.org/10.1016/j.dcmed.2019.12.005openalex-snapshot
Antioxidant Nature Adds Further Therapeutic Value: An Updated Review on Natural Xanthones and Their Glycosides
inferred← citeshttps://doi.org/10.1016/j.gde.2018.07.005openalex-snapshot
Biophysical control of the cell rearrangements and cell shape changes that build epithelial tissues
inferred← citeshttps://doi.org/10.1016/j.heliyon.2021.e07024openalex-snapshot
Synthesis and evaluation of the in vitro and in vivo antitrypanosomal activity of 2-styrylquinolines
inferred← citeshttps://doi.org/10.1016/j.imu.2024.101485openalex-snapshot
In-silico studies of hydroxyxanthone derivatives as potential pfDHFR and pfDHODH inhibitor by molecular docking, molecular dynamics simulation, MM-PBSA calculation and pharmacokinetics prediction
inferred← citeshttps://doi.org/10.1016/j.jneuroim.2016.05.008openalex-snapshot
Alpha-mangostin attenuates brain inflammation induced by peripheral lipopolysaccharide administration in C57BL/6J mice
inferred← citeshttps://doi.org/10.1016/j.kjms.2016.12.003openalex-snapshot
Development and in vivo evaluation of self‐microemulsion as delivery system for α‐mangostin
inferred← citeshttps://doi.org/10.1016/j.phymed.2023.155069openalex-snapshot
Reversing the biofilm-inducing effect of two xanthones from Garcinia mangostana by 3-methyl-2(5H)-furanone and N-butyryl-D-L homoserine lactone
inferred← citeshttps://doi.org/10.1016/j.phyplu.2022.100253openalex-snapshot
A Review on Synthetic and Pharmacological Potential of Compounds Isolated from Garcinia mangostana Linn
inferred← citeshttps://doi.org/10.1016/j.tet.2016.09.018openalex-snapshot
Antimalarial polyoxygenated and prenylated xanthones from the leaves and branches of Garcinia mckeaniana
inferred← citeshttps://doi.org/10.1016/s1875-5364(17)30024-9openalex-snapshot
Pharmacology of mangostins and their derivatives: A comprehensive review
inferred← citeshttps://doi.org/10.1021/acs.jafc.0c04439openalex-snapshot
Identification and Pharmacokinetics of Quinone Reductase 2 Inhibitors after Oral Administration of Garcinia mangostana L. Extract in Rat by LC–MS/MS
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.7b01348openalex-snapshot
Semisynthesis and Biological Evaluation of Xanthone Amphiphilics as Selective, Highly Potent Antifungal Agents to Combat Fungal Resistance
inferred← citeshttps://doi.org/10.1021/acs.orglett.5c03290openalex-snapshot
Asymmetric Synthesis of Cycloartobiloxanthone
inferred← citeshttps://doi.org/10.1038/s41598-021-87381-xopenalex-snapshot
Anti-Acanthamoeba synergistic effect of chlorhexidine and Garcinia mangostana extract or α-mangostin against Acanthamoeba triangularis trophozoite and cyst forms
inferred← citeshttps://doi.org/10.1039/c5md00481kopenalex-snapshot
Focus on PAINS: false friends in the quest for selective anti-protozoal lead structures from Nature?
inferred← citeshttps://doi.org/10.1055/a-1148-9000openalex-snapshot
Natural Phenolic Compounds and Derivatives as Potential Antimalarial Agents
inferred← citeshttps://doi.org/10.1080/07391102.2023.2214237openalex-snapshot
Mechanistic insight of α-mangostin encapsulation in 2-hydroxypropyl-β-cyclodextrin for solubility enhancement
inferred← citeshttps://doi.org/10.1080/13543776.2018.1455829openalex-snapshot
Bioactivity and pharmacological properties of α-mangostin from the mangosteen fruit: a review
inferred← citeshttps://doi.org/10.1108/jhr-08-2018-043openalex-snapshot
Biological properties in relation to health promotion effects of Garcinia mangostana (queen of fruit)
inferred← citeshttps://doi.org/10.1177/09731296241262567openalex-snapshot
Isolation and Pharmacochemistry of α-Mangostin as a Chemotherapeutic Agent
inferred← citeshttps://doi.org/10.1177/1934578x20974559openalex-snapshot
Characterization, Release Pattern, and Cytotoxicity of Liposomes Loaded With α-Mangostin Isolated From Pericarp of Mangosteen ( Garcinia mangostana L.)
inferred← citeshttps://doi.org/10.1177/1934578x221133582openalex-snapshot
In Vitro and in Vivo Evaluation of the Antimalarial Activities of Kniphofia reflexa Hutchinson ex Codd
inferred← citeshttps://doi.org/10.1186/s12906-024-04427-zopenalex-snapshot
In vivo antimalarial effect of 1-hydroxy-5,6,7-trimethoxyxanthone isolated from Mammea siamensis T. Anders. flowers: pharmacokinetic and acute toxicity studies
inferred← citeshttps://doi.org/10.1186/s12936-019-3026-1openalex-snapshot
Antiplasmodial natural products: an update
inferred← citeshttps://doi.org/10.1515/znb-2021-0077openalex-snapshot
Antileishmanial, antibacterial and cytotoxicity activity of the extracts, fractions, and compounds from the fruits and stem bark extracts of Pentadesma butyracea Sabine
inferred← citeshttps://doi.org/10.18632/oncotarget.27159openalex-snapshot
Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone
inferred← citeshttps://doi.org/10.21577/0100-4042.20170954openalex-snapshot
O POTENCIAL DA XANTONA NATURAL α-MANGOSTINA NO DESENVOLVIMENTO DE NOVOS AGENTES ANTI-INFECCIOSOS: UMA REVISÃO
inferred← citeshttps://doi.org/10.2174/0109298673312729250514115343openalex-snapshot
Exploring the Multitarget Therapeutic Potential of Mangostin Derivatives
inferred← citeshttps://doi.org/10.2174/1570159x22666240212142655openalex-snapshot
A Mechanistic Review on Protective Effects of Mangosteen and its Xanthones Against Hazardous Materials and Toxins
inferred← citeshttps://doi.org/10.22034/apjcp.2017.18.3.707openalex-snapshot
In Vitro and In Vivo Inhibitory Effects of α-Mangostin on Cholangiocarcinoma Cells and Allografts
inferred← citeshttps://doi.org/10.3390/antiox13020207openalex-snapshot
Molecular Mechanism of Natural Food Antioxidants to Regulate ROS in Treating Cancer: A Review
inferred← citeshttps://doi.org/10.3390/ijms21144988openalex-snapshot
Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components
inferred← citeshttps://doi.org/10.3390/md21120609openalex-snapshot
Therapeutic Potential of Marine-Derived Cyclic Peptides as Antiparasitic Agents
inferred← citeshttps://doi.org/10.3390/molecules25235690openalex-snapshot
Phytochemicals and Biological Activities of Garcinia morella (Gaertn.) Desr.: A Review
inferred← citeshttps://doi.org/10.3390/molecules28031104openalex-snapshot
N-Containing α-Mangostin Analogs via Smiles Rearrangement as the Promising Cytotoxic, Antitrypanosomal, and SARS-CoV-2 Main Protease Inhibitory Agents
inferred← citeshttps://doi.org/10.3390/pharmaceutics13121993openalex-snapshot
Nanoformulations of α-Mangostin for Cancer Drug Delivery System
inferred← citeshttps://doi.org/10.3892/br.2021.1424openalex-snapshot
α-mangostin preserves hepatic microvascular architecture in fibrotic rats as shown by scanning electron microscopy of vascular corrosion casts
inferred← citeshttps://doi.org/10.67867/ccj.2026v10i3.10openalex-snapshot
Phytochemicals targeting diabetes and malaria: Chemical diversity, mechanistic insights, and prospects for dual-action therapeutics
inferred← citeshttps://doi.org/10.7287/peerj.15329v0.1/reviews/1openalex-snapshot
Peer Review #1 of "Botanical characteristics, chemical components, biological activity, and potential applications of mangosteen (v0.1)"
inferred← citeshttps://doi.org/10.7287/peerj.15329v0.1/reviews/2openalex-snapshot
Peer Review #2 of "Botanical characteristics, chemical components, biological activity, and potential applications of mangosteen (v0.1)"
inferred← citeshttps://doi.org/10.7287/peerj.15329v0.1/reviews/3openalex-snapshot
Peer Review #3 of "Botanical characteristics, chemical components, biological activity, and potential applications of mangosteen (v0.1)"
inferred← citeshttps://doi.org/10.7287/peerj.15329v0.2/reviews/1openalex-snapshot
Peer Review #1 of "Botanical characteristics, chemical components, biological activity, and potential applications of mangosteen (v0.2)"
inferred← citeshttps://doi.org/10.7287/peerj.15329v0.2/reviews/2openalex-snapshot
Peer Review #2 of "Botanical characteristics, chemical components, biological activity, and potential applications of mangosteen (v0.2)"
inferred← citeshttps://doi.org/10.7717/peerj.15329openalex-snapshot
Botanical characteristics, chemical components, biological activity, and potential applications of mangosteen
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