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Curcumin in epilepsy disorders

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/0471142301.ns0937s58openalex-snapshot

Pentylenetetrazol (PTZ) Kindling Model of Epilepsy

inferredcites →https://doi.org/10.1002/glia.22317openalex-snapshot

Aquaporin‐4 and epilepsy

inferredcites →https://doi.org/10.1002/ptr.2551openalex-snapshot

Curcumin has anticonvulsant activity on increasing current electroshock seizures in mice

inferredcites →https://doi.org/10.1007/978-0-387-46401-5_1openalex-snapshot

CURCUMIN: THE INDIAN SOLID GOLD

inferredcites →https://doi.org/10.1007/978-0-387-46401-5_21openalex-snapshot

CLINICAL STUDIES WITH CURCUMIN

inferredcites →https://doi.org/10.1007/978-0-387-46401-5_3openalex-snapshot

ANTIOXIDANT AND ANTI-INFLAMMATORY PROPERTIES OF CURCUMIN

inferredcites →https://doi.org/10.1007/s00216-010-3719-3openalex-snapshot

A validated method for the quantification of curcumin in plasma and brain tissue by fast narrow-bore high-performance liquid chromatography with fluorescence detection

inferredcites →https://doi.org/10.1007/s11011-017-0017-1openalex-snapshot

Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress

inferredcites →https://doi.org/10.1007/s11011-017-0100-7openalex-snapshot

Curcumin-supplemented diets improve antioxidant enzymes and alter acetylcholinesterase genes expression level in Drosophila melanogaster model

inferredcites →https://doi.org/10.1007/s11064-011-0544-9openalex-snapshot

The Neuroprotective Effect of Curcumin and Nigella sativa Oil Against Oxidative Stress in the Pilocarpine Model of Epilepsy: A Comparison with Valproate

inferredcites →https://doi.org/10.1007/s11064-011-0607-yopenalex-snapshot

L-Type Calcium Channel Mediates Anticonvulsant Effect of Cannabinoids in Acute and Chronic Murine Models of Seizure

inferredcites →https://doi.org/10.1007/s12031-017-0968-zopenalex-snapshot

Inhibition of P2X7 Receptor Ameliorates Nuclear Factor-Kappa B Mediated Neuroinflammation Induced by Status Epilepticus in Rat Hippocampus

inferredcites →https://doi.org/10.1016/j.biopha.2017.04.070openalex-snapshot

Curcumin attenuates lipopolysaccharide/d-galactosamine-induced acute liver injury by activating Nrf2 nuclear translocation and inhibiting NF-kB activation

inferredcites →https://doi.org/10.1016/j.brainres.2008.01.104openalex-snapshot

Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB

inferredcites →https://doi.org/10.1016/j.brainres.2010.07.007openalex-snapshot

GABAergic and nitriergic modulation by curcumin for its antianxiety-like activity in mice

inferredcites →https://doi.org/10.1016/j.cbi.2008.05.003openalex-snapshot

Antioxidant and radical scavenging properties of curcumin

inferredcites →https://doi.org/10.1016/j.cbi.2012.11.024openalex-snapshot

NMDA and AMPA receptor mediated excitotoxicity in cerebral cortex of streptozotocin induced diabetic rat: Ameliorating effects of curcumin

inferredcites →https://doi.org/10.1016/j.ceca.2012.11.014openalex-snapshot

Inhibition of L-type Ca2+ channels by curcumin requires a novel protein kinase-theta isoform in rat hippocampal neurons

inferredcites →https://doi.org/10.1016/j.ejphar.2010.07.022openalex-snapshot

Curcumin ameliorates cognitive dysfunction and oxidative damage in phenobarbitone and carbamazepine administered rats

inferredcites →https://doi.org/10.1016/j.ejphar.2013.02.012openalex-snapshot

Ameliorative effect of Curcumin on seizure severity, depression like behavior, learning and memory deficit in post-pentylenetetrazole-kindled mice

inferredcites →https://doi.org/10.1016/j.eplepsyres.2007.10.008openalex-snapshot

Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor increases pentylenetetrazol seizure threshold in mice: Possible involvement of adenosinergic mechanism

inferredcites →https://doi.org/10.1016/j.expneurol.2017.06.009openalex-snapshot

Enhanced classical complement pathway activation and altered phagocytosis signaling molecules in human epilepsy

inferredcites →https://doi.org/10.1016/j.foodchem.2011.01.059openalex-snapshot

Optimised nano-formulation on the bioavailability of hydrophobic polyphenol, curcumin, in freely-moving rats

inferredcites →https://doi.org/10.1016/j.ijpharm.2011.06.030openalex-snapshot

Curcumin and its nano-formulation: The kinetics of tissue distribution and blood–brain barrier penetration

inferredcites →https://doi.org/10.1016/j.lfs.2010.09.006openalex-snapshot

Protective effect of curcumin against seizures and cognitive impairment in a pentylenetetrazole-kindled epileptic rat model

inferredcites →https://doi.org/10.1016/j.lfs.2016.08.011openalex-snapshot

Ferulic acid exhibits antiepileptogenic effect and prevents oxidative stress and cognitive impairment in the kindling model of epilepsy

inferredcites →https://doi.org/10.1016/j.lfs.2017.06.023openalex-snapshot

Potential therapeutic and protective effect of curcumin against stroke in the male albino stroke-induced model rats

inferredcites →https://doi.org/10.1016/j.neuint.2015.07.009openalex-snapshot

Curcumin attenuates inflammatory response and cognitive deficits in experimental model of chronic epilepsy

inferredcites →https://doi.org/10.1016/j.neuroscience.2015.09.058openalex-snapshot

Protection against cognitive impairment and modification of epileptogenesis with curcumin in a post-status epilepticus model of temporal lobe epilepsy

inferredcites →https://doi.org/10.1016/j.pbb.2011.05.011openalex-snapshot

Pharmacokinetic and pharmacodynamic interactions of valproate, phenytoin, phenobarbitone and carbamazepine with curcumin in experimental models of epilepsy in rats

inferredcites →https://doi.org/10.1016/j.pediatrneurol.2017.09.013openalex-snapshot

Antiepileptic Drugs and Liver Disease

inferredcites →https://doi.org/10.1016/j.phymed.2010.11.007openalex-snapshot

Modulation of pentylenetetrazole-induced kindling and oxidative stress by curcumin in mice

inferredcites →https://doi.org/10.1016/j.pnpbp.2006.06.003openalex-snapshot

Effect of cyclooxygenase inhibitors on pentylenetetrazol (PTZ)-induced convulsions: Possible mechanism of action

inferredcites →https://doi.org/10.1016/j.pnpbp.2017.07.025openalex-snapshot

Curcumin-loaded chitosan-alginate-STPP nanoparticles ameliorate memory deficits and reduce glial activation in pentylenetetrazol-induced kindling model of epilepsy

inferredcites →https://doi.org/10.1016/j.seizure.2007.05.016openalex-snapshot

Neuroprotective effect of nimesulide, a preferential COX-2 inhibitor, against pentylenetetrazol (PTZ)-induced chemical kindling and associated biochemical parameters in mice

inferredcites →https://doi.org/10.1016/j.sjbs.2013.01.002openalex-snapshot

Protective effects of curcumin against lithium–pilocarpine induced status epilepticus, cognitive dysfunction and oxidative stress in young rats

inferredcites →https://doi.org/10.1016/j.xphs.2017.11.014openalex-snapshot

Curcumin Cocrystal Micelles—Multifunctional Nanocomposites for Management of Neurodegenerative Ailments

inferredcites →https://doi.org/10.1016/j.yebeh.2008.11.011openalex-snapshot

Curcumin protects against electrobehavioral progression of seizures in the iron-induced experimental model of epileptogenesis

inferredcites →https://doi.org/10.1016/s0920-1211(02)00073-6openalex-snapshot

Animal models of epilepsy for the development of antiepileptogenic and disease-modifying drugs. A comparison of the pharmacology of kindling and post-status epilepticus models of temporal lobe epilepsy

inferredcites →https://doi.org/10.1021/jm0607193openalex-snapshot

Curcumin and Dehydrozingerone Derivatives: Synthesis, Radiolabeling, and Evaluation for β-Amyloid Plaque Imaging†

inferredcites →https://doi.org/10.1021/ol000173topenalex-snapshot

On the Antioxidant Mechanism of Curcumin: Classical Methods Are Needed To Determine Antioxidant Mechanism and Activity

inferredcites →https://doi.org/10.1038/nrneurol.2010.178openalex-snapshot

The role of inflammation in epilepsy

inferredcites →https://doi.org/10.1038/s41598-018-20897-xopenalex-snapshot

Micronization potentiates curcumin’s anti-seizure effect and brings an important advance in epilepsy treatment

inferredcites →https://doi.org/10.1039/c4cc03731fopenalex-snapshot

A bifunctional curcumin analogue for two-photon imaging and inhibiting crosslinking of amyloid beta in Alzheimer's disease

inferredcites →https://doi.org/10.1080/0886022x.2016.1214892openalex-snapshot

Curcumin alleviates ischemia reperfusion-induced acute kidney injury through NMDA receptor antagonism in rats

inferredcites →https://doi.org/10.1093/hmg/ddw410openalex-snapshot

Identifying new antiepileptic drugs through genomics-based drug repurposing

inferredcites →https://doi.org/10.1111/epi.13345openalex-snapshot

Effects of rapamycin and curcumin treatment on the development of epilepsy after electrically induced status epilepticus in rats

inferredcites →https://doi.org/10.1111/j.1471-4159.2010.06630.xopenalex-snapshot

Curcumin attenuates cerebral edema following traumatic brain injury in mice: a possible role for aquaporin‐4?

inferredcites →https://doi.org/10.1111/j.1472-8206.2011.01002.xopenalex-snapshot

Liposomal formulation of curcumin attenuates seizures in different experimental models of epilepsy in mice

inferredcites →https://doi.org/10.1111/j.1528-1167.2012.03513.xopenalex-snapshot

Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood–brain barrier leakage but not microglia activation

inferredcites →https://doi.org/10.1111/j.1535-7511.2009.01342.xopenalex-snapshot

Herbs and Spices: Unexpected Sources of Antiepileptogenic Drug Treatments?

inferredcites →https://doi.org/10.1124/pr.110.004044openalex-snapshot

The Molecular Basis for the Pharmacokinetics and Pharmacodynamics of Curcumin and Its Metabolites in Relation to Cancer

inferredcites →https://doi.org/10.1139/cjpp-2016-0154openalex-snapshot

Curcumin protects neuronal cells against status-epilepticus-induced hippocampal damage through induction of autophagy and inhibition of necroptosis

inferredcites →https://doi.org/10.1152/ajprenal.0140.2001openalex-snapshot

Mechanism of heme oxygenase-1 gene induction by curcumin in human renal proximal tubule cells

inferredcites →https://doi.org/10.1155/2015/706207openalex-snapshot

Curcumin Protects Neurons from Glutamate-Induced Excitotoxicity by Membrane Anchored AKAP79-PKA Interaction Network

inferredcites →https://doi.org/10.1158/1078-0432.ccr-08-0024openalex-snapshot

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

inferredcites →https://doi.org/10.1167/iovs.10-5966openalex-snapshot

Curcumin Protects against NMDA-Induced Toxicity: A Possible Role for NR2A Subunit

inferredcites →https://doi.org/10.1177/0883073817739528openalex-snapshot

Role of Neuroinflammation in Evolution of Childhood Epilepsy

inferredcites →https://doi.org/10.1186/alzrt146openalex-snapshot

Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study

inferredcites →https://doi.org/10.1186/s12906-017-1922-xopenalex-snapshot

Neuroprotective properties of curcumin in toxin-base animal models of Parkinson’s disease: a systematic experiment literatures review

inferredcites →https://doi.org/10.1358/mf.2010.32.4.1452090openalex-snapshot

Antioxidant potential of curcumin against oxidative insult induced by pentylenetetrazol in epileptic rats

inferredcites →https://doi.org/10.17113/ftb.52.04.14.3622openalex-snapshot

Curcumin-Protected PC12 Cells Against Glutamate-Induced Oxidative Toxicity

inferredcites →https://doi.org/10.2174/1381612823666170926113754openalex-snapshot

Inflammation and Epilepsy: Preclinical Findings and Potential Clinical Translation

inferredcites →https://doi.org/10.2174/1570159x11311040002openalex-snapshot

Curcumin and its Derivatives: Their Application in Neuropharmacology and Neuroscience in the 21st Century

inferredcites →https://doi.org/10.3109/10799893.2015.1108337openalex-snapshot

Curcumin inhibits apoptosis by regulating intracellular calcium release, reactive oxygen species and mitochondrial depolarization levels in SH-SY5Y neuronal cells

inferredcites →https://doi.org/10.3109/13880209.2013.803128openalex-snapshot

Antiepileptogenic effect of curcumin on kainate-induced model of temporal lobe epilepsy

inferredcites →https://doi.org/10.3233/bme-151376openalex-snapshot

The involvement of neuronal nitric oxide synthase in the anti-epileptic action of curcumin on pentylenetetrazol-kindled rats

inferredcites →https://doi.org/10.3233/jad-170354openalex-snapshot

The Natural Product Curcumin as a Potential Coadjuvant in Alzheimer’s Treatment

inferredcites →https://doi.org/10.3389/fchem.2014.00113openalex-snapshot

Farmer to pharmacist: curcumin as an anti-invasive and antimetastatic agent for the treatment of cancer1

inferredcites →https://doi.org/10.3389/fneur.2017.00301openalex-snapshot

Drug-Resistant Epilepsy: Multiple Hypotheses, Few Answers

inferredcites →https://doi.org/10.3389/fphys.2014.00094openalex-snapshot

Effects of curcumin on ion channels and transporters

inferredcites →https://doi.org/10.3390/ijms13079097openalex-snapshot

Curcumin Inhibits Glutamate Release from Rat Prefrontal Nerve Endings by Affecting Vesicle Mobilization

inferredcites →https://doi.org/10.3390/ijms160818348openalex-snapshot

Overview of Nrf2 as Therapeutic Target in Epilepsy

inferredcites →https://doi.org/10.3892/mmr.2014.3079openalex-snapshot

Curcumin and its major metabolites inhibit the inflammatory response induced by lipopolysaccharide: Translocation of nuclear factor-κB as potential target

inferredcites →https://doi.org/10.4103/0250-474x.65012openalex-snapshot

An overview of curcumin in neurological disorders

inferredcites →https://doi.org/10.5530/ijper.52.1.4openalex-snapshot

Curcumin: The Molecular Mechanisms of Action in Inflammation and Cell Death during Kainate-Induced Epileptogenesis

inferredcites →https://doi.org/10.7508/rmm.2015.01.005openalex-snapshot

Effect of Curcumin on the Hypothalamus Levels of the Potent Inhibitory Neurotransmitter ,Gamma aminobutyric acid

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4519385openalex-extracted

Difficulties Faced in Replicating the Standard Lithium Pilocarpine Model of Temporal Lobe Epilepsy in Wistar Rats and Suggested Troubleshooting

inferred← citeshttps://doi.org/10.1002/advs.202405263openalex-snapshot

Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation‐Associated Microglial Response

inferred← citeshttps://doi.org/10.1002/brb3.70625openalex-snapshot

Proteome‐Wide and Immune Cell Phenotype Mendelian Randomization Highlights Immune Involvement in Genetic Generalized Epilepsy

inferred← citeshttps://doi.org/10.1002/fft2.70376openalex-snapshot

Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy

inferred← citeshttps://doi.org/10.1002/ptr.6467openalex-snapshot

Therapeutic effects of curcumin on sepsis and mechanisms of action: A systematic review of preclinical studies

inferred← citeshttps://doi.org/10.1002/ptr.6617openalex-snapshot

Natural polyphenols in preclinical models of epilepsy

inferred← citeshttps://doi.org/10.1002/ptr.6635openalex-snapshot

An updated PTR virtual issue on the pharmacology of the nutraceutical curcumin

inferred← citeshttps://doi.org/10.1002/ptr.8265openalex-snapshot

Curcumin and nano‐curcumin applications in psychiatric disorders

inferred← citeshttps://doi.org/10.1007/978-3-030-39855-2_7openalex-snapshot

Adjuvant Value of Turmeric Extract (Containing Curcumin) in Colorectal Cancer Management

inferred← citeshttps://doi.org/10.1007/978-3-031-41188-5_8openalex-snapshot

Role of Endogenous and Dietary Antioxidants in Brain Disorders

inferred← citeshttps://doi.org/10.1007/978-981-19-3949-5_17-1openalex-snapshot

The Role of Neurotransmitters in Epileptogenesis: Focus on GABA and Glutamate

inferred← citeshttps://doi.org/10.1007/978-981-19-3949-5_17-2openalex-snapshot

The Role of Neurotransmitters in Epileptogenesis: Focus on GABA and Glutamate

inferred← citeshttps://doi.org/10.1007/978-981-99-0677-2_15openalex-snapshot

Advantages and Disadvantages of Nutraceuticals

inferred← citeshttps://doi.org/10.1007/978-981-99-7557-0_17openalex-snapshot

The Role of Neurotransmitters in Epileptogenesis: Focus on GABA and Glutamate

inferred← citeshttps://doi.org/10.1007/s10787-025-02053-wopenalex-snapshot

Therapeutic effects of curcumin on seizure and its mechanisms of action

inferred← citeshttps://doi.org/10.1016/b978-0-323-90052-2.00043-3openalex-snapshot

Curcumin usage in epilepsy

inferred← citeshttps://doi.org/10.1016/j.eplepsyres.2020.106282openalex-snapshot

Therapeutic role of targeting mTOR signaling and neuroinflammation in epilepsy

inferred← citeshttps://doi.org/10.1016/j.eplepsyres.2022.106873openalex-snapshot

No persistent effects of intracerebral curcumin administration on seizure progression and neuropathology in the kindling rat model for temporal lobe epilepsy

inferred← citeshttps://doi.org/10.1016/j.prenap.2026.100810openalex-snapshot

A comprehensive review on antioxidant properties of ethnochemical curcumin: Molecular mechanisms and clinical implications

inferred← citeshttps://doi.org/10.1016/j.talanta.2020.121104openalex-snapshot

Luminescence of Eu (III) complex under near-infrared light excitation for curcumin detection

inferred← citeshttps://doi.org/10.1016/j.yebeh.2020.107701openalex-snapshot

Enlightening the neuroprotective effect of quercetin in epilepsy: From mechanism to therapeutic opportunities

inferred← citeshttps://doi.org/10.1016/j.yebeh.2025.110400openalex-snapshot

Balancing efficacy and safety: The dual impact of antiseizure medications on the developing brain

inferred← citeshttps://doi.org/10.1021/acsomega.4c00825openalex-snapshot

Identification of Curcumin Targets in the Brain of Epileptic Mice Using DARTS

inferred← citeshttps://doi.org/10.1038/s41598-025-29653-4openalex-snapshot

Mechanisms of curcumin adsorption in metal-substituted MOF-74 frameworks using DFT and MD simulations

inferred← citeshttps://doi.org/10.1039/d4fo05464dopenalex-snapshot

Cynarin protects against seizures and neuronal death in a rat model of kainic acid-induced seizures

inferred← citeshttps://doi.org/10.1055/a-1948-4378openalex-snapshot

PET Imaging and Neurohistochemistry Reveal that Curcumin Attenuates Brain Hypometabolism and Hippocampal Damage Induced by Status Epilepticus in Rats

inferred← citeshttps://doi.org/10.1080/00498254.2022.2136044openalex-snapshot

Curcumin-loaded hydroxypropyl-β-cyclodextrin inclusion complex with enhanced dissolution and oral bioavailability for epilepsy treatment

inferred← citeshttps://doi.org/10.1093/med/9780197549469.003.0031openalex-snapshot

Role of Reactive Oxygen Species in Epilepsy

inferred← citeshttps://doi.org/10.2147/ijn.s208332openalex-snapshot

Curcumin-loaded nanoparticles: a novel therapeutic strategy in treatment of central nervous system disorders

inferred← citeshttps://doi.org/10.26820/reciamuc/6.(3).julio.2022.556-563openalex-snapshot

Eficacia de la dieta cetogénica con aceite de cúrcuma en pacientes pediátricos con epilepsia fármaco dependiente

inferred← citeshttps://doi.org/10.32598/ppj.25.1.80openalex-snapshot

Anticonvulsant effect of acute curcumin nanoparticle on pentylenetetrazole-induced seizures in mice: non-involvement of JNK restoration

inferred← citeshttps://doi.org/10.3389/fnmol.2023.1221665openalex-snapshot

Zebrafish as a robust preclinical platform for screening plant-derived drugs with anticonvulsant properties—a review

inferred← citeshttps://doi.org/10.3389/fphar.2022.893118openalex-snapshot

Mechanisms Underlying Curcumin-Induced Neuroprotection in Cerebral Ischemia

inferred← citeshttps://doi.org/10.3390/antiox11010157openalex-snapshot

The Interconnected Mechanisms of Oxidative Stress and Neuroinflammation in Epilepsy

inferred← citeshttps://doi.org/10.3390/ijms252312943openalex-snapshot

The Oxidative Stress in Epilepsy—Focus on Melatonin

inferred← citeshttps://doi.org/10.3390/molecules24102023openalex-snapshot

Preparation, Characterization, and Release Kinetics of Chitosan-Coated Nanoliposomes Encapsulating Curcumin in Simulated Environments

inferred← citeshttps://doi.org/10.3390/molecules26061592openalex-snapshot

Neuroprotective Effects of Thymoquinone by the Modulation of ER Stress and Apoptotic Pathway in In Vitro Model of Excitotoxicity

inferred← citeshttps://doi.org/10.3390/ph17121611openalex-snapshot

Anti-Epileptic Activity of Mitocurcumin in a Zebrafish–Pentylenetetrazole (PTZ) Epilepsy Model

inferred← citeshttps://doi.org/10.36118/pharmadvances.2021.06openalex-snapshot

The pharmacological basis of the curcumin nutraceutical uses: an update

inferred← citeshttps://doi.org/10.47583/ijpsrr.2022.v76i01.022openalex-snapshot

Pharmacological Facet of Curcuma longa: A Review

inferred← citeshttps://doi.org/10.5493/wjem.v15.i2.104328openalex-snapshot

Unraveling the nutritional challenges in epilepsy: Risks, deficiencies, and management strategies: A systematic review

inferred← citeshttps://doi.org/10.61186/ibj.3978openalex-snapshot

Curcumin Lowers the Accelerated Speed of Epileptogenesis by Traumatic Brain Injury

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