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Concise Review: Boosting T-Cell Reconstitution Following Allogeneic Transplantation—Current Concepts and Future Perspectives
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ajh.21907openalex-snapshot
In vivo T‐cell depletion with pretransplant low‐dose antithymocyte globulin is associated with reduced transplant‐related mortality and improved clinical outcome in patients receiving allogeneic hematopoietic stem cell transplantation from unrelated and partially matched related donors
inferredcites →https://doi.org/10.1002/pbc.25347openalex-snapshot
Impact of very early CD4 + /CD8 + T cell counts on the occurrence of acute graft‐versus‐host disease and NK cell counts on outcome after pediatric allogeneic hematopoietic stem cell transplantation
inferredcites →https://doi.org/10.1002/stem.1145openalex-snapshot
Human T‐Lymphoid Progenitors Generated in a Feeder‐Cell‐Free Delta‐Like‐4 Culture System Promote T‐Cell Reconstitution in NOD/SCID/γc −/− Mice
inferredcites →https://doi.org/10.1007/s00281-008-0132-5openalex-snapshot
Reconstitution of the immune system after hematopoietic stem cell transplantation in humans
inferredcites →https://doi.org/10.1007/s12026-010-8191-9openalex-snapshot
Transplantation of hematopoietic stem cells in human severe combined immunodeficiency: longterm outcomes
inferredcites →https://doi.org/10.1016/j.bbmt.2012.08.014openalex-snapshot
Unmanipulated Haploidentical Bone Marrow Transplantation and Posttransplantation Cyclophosphamide for Hematologic Malignancies after Myeloablative Conditioning
inferredcites →https://doi.org/10.1016/j.bbmt.2012.10.010openalex-snapshot
Immune Reconstitution Kinetics as an Early Predictor for Mortality using Various Hematopoietic Stem Cell Sources in Children
inferredcites →https://doi.org/10.1016/j.bbmt.2016.11.016openalex-snapshot
Nonmyeloablative Haploidentical Bone Marrow Transplantation with Post-Transplantation Cyclophosphamide for Pediatric and Young Adult Patients with High-Risk Hematologic Malignancies
inferredcites →https://doi.org/10.1016/j.bbmt.2017.10.004openalex-snapshot
Virus-Specific T Cells: Broadening Applicability
inferredcites →https://doi.org/10.1016/j.cyto.2016.01.003openalex-snapshot
Homeostatic cytokines in immune reconstitution and graft-versus-host disease
inferredcites →https://doi.org/10.1016/j.it.2004.11.002openalex-snapshot
IL-7 and IL-15: therapeutic cytokines for immunodeficiency
inferredcites →https://doi.org/10.1016/j.jaci.2014.08.019openalex-snapshot
CD45RA depletion in HLA-mismatched allogeneic hematopoietic stem cell transplantation for primary combined immunodeficiency: A preliminary study
inferredcites →https://doi.org/10.1016/j.jaci.2016.03.032openalex-snapshot
Specific T cells for the treatment of cytomegalovirus and/or adenovirus in the context of hematopoietic stem cell transplantation
inferredcites →https://doi.org/10.1016/j.jaci.2016.12.992openalex-snapshot
Viral reactivations and associated outcomes in the context of immune reconstitution after pediatric hematopoietic cell transplantation
inferredcites →https://doi.org/10.1016/j.jaci.2017.10.034openalex-snapshot
Generation of adult human T-cell progenitors for immunotherapeutic applications
inferredcites →https://doi.org/10.1016/s0140-6736(02)09413-8openalex-snapshot
Immune reconstitution without graft-versus-host disease after haemopoietic stem-cell transplantation: a phase 1/2 study
inferredcites →https://doi.org/10.1016/s0140-6736(81)90647-4openalex-snapshot
TRANSPLANTATION FOR ACUTE LEUKAEMIA WITH HLA-A AND B NONIDENTICAL PARENTAL MARROW CELLS FRACTIONATED WITH SOYBEAN AGGLUTININ AND SHEEP RED BLOOD CELLS
inferredcites →https://doi.org/10.1016/s0140-6736(95)91150-2openalex-snapshot
Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation
inferredcites →https://doi.org/10.1016/s1470-2045(09)70074-9openalex-snapshot
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I–II study
inferredcites →https://doi.org/10.1038/3877openalex-snapshot
Defective IL7R expression in T-B+NK+ severe combined immunodeficiency
inferredcites →https://doi.org/10.1038/80868openalex-snapshot
Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo
inferredcites →https://doi.org/10.1038/bmt.2013.114openalex-snapshot
Depletion of naive T cells using clinical grade magnetic CD45RA beads: a new approach for GVHD prophylaxis
inferredcites →https://doi.org/10.1038/bmt.2013.47openalex-snapshot
Interleukin-15 administration increases graft-versus-tumor activity in recipients of haploidentical hematopoietic SCT
inferredcites →https://doi.org/10.1038/bmt.2015.93openalex-snapshot
Unmanipulated haploidentical bone marrow transplantation and post-transplant cyclophosphamide for hematologic malignanices following a myeloablative conditioning: an update
inferredcites →https://doi.org/10.1038/ni.1695openalex-snapshot
Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells
inferredcites →https://doi.org/10.1038/nmeth.4258openalex-snapshot
Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1
inferredcites →https://doi.org/10.1053/j.seminhematol.2016.01.005openalex-snapshot
Haploidentical bone marrow and stem cell transplantation: experience with post-transplantation cyclophosphamide
inferredcites →https://doi.org/10.1053/j.seminhematol.2016.01.012openalex-snapshot
Haploidentical transplantation: selecting optimal conditioning regimen and stem cell source
inferredcites →https://doi.org/10.1056/nejm199510193331603openalex-snapshot
Reconstitution of Cellular Immunity against Cytomegalovirus in Recipients of Allogeneic Bone Marrow by Transfer of T-Cell Clones from the Donor
inferredcites →https://doi.org/10.1073/pnas.0911726107openalex-snapshot
Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia
inferredcites →https://doi.org/10.1073/pnas.2436348100openalex-snapshot
Rapamycin is active against B-precursor leukemia in vitro and in vivo , an effect that is modulated by IL-7-mediated signaling
inferredcites →https://doi.org/10.1080/1744666x.2017.1381558openalex-snapshot
Long term outcomes of severe combined immunodeficiency: therapy implications
inferredcites →https://doi.org/10.1084/jem.20020066openalex-snapshot
Interleukin (IL)-15 and IL-7 Jointly Regulate Homeostatic Proliferation of Memory Phenotype CD8+ Cells but Are Not Required for Memory Phenotype CD4+ Cells
inferredcites →https://doi.org/10.1084/jem.20071681openalex-snapshot
Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets
inferredcites →https://doi.org/10.1084/jem.20080829openalex-snapshot
Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment
inferredcites →https://doi.org/10.1084/jem.20131289openalex-snapshot
Sex steroid blockade enhances thymopoiesis by modulating Notch signaling
inferredcites →https://doi.org/10.1093/cid/ciq042openalex-snapshot
Directly Selected Cytomegalovirus-Reactive Donor T Cells Confer Rapid and Safe Systemic Reconstitution of Virus-Specific Immunity Following Stem Cell Transplantation
inferredcites →https://doi.org/10.1097/01.cji.0000210386.55951.c2openalex-snapshot
IL-7 Administration to Humans Leads to Expansion of CD8+ and CD4+ Cells but a Relative Decrease of CD4+ T-Regulatory Cells
inferredcites →https://doi.org/10.1097/01.tp.0000070167.81584.a2openalex-snapshot
Insulin-like growth factor-I enhances lymphoid and myeloid reconstitution after allogeneic bone marrow transplantation12
inferredcites →https://doi.org/10.1097/01.tp.0000183962.64777.daopenalex-snapshot
Sex Steroid Ablation Enhances Lymphoid Recovery Following Autologous Hematopoietic Stem Cell Transplantation
inferredcites →https://doi.org/10.1097/moh.0b013e328353bc7dopenalex-snapshot
Immune reconstitution after hematopoietic cell transplantation
inferredcites →https://doi.org/10.1111/imr.12417openalex-snapshot
Hematopoiesis and T‐cell specification as a model developmental system
inferredcites →https://doi.org/10.1111/j.1365-2141.2004.05134.xopenalex-snapshot
IL‐7 effect on immunological reconstitution after HSCT depends on MHC incompatibility
inferredcites →https://doi.org/10.1111/j.1399-0039.2011.01820.xopenalex-snapshot
Thymus and immune reconstitution after allogeneic hematopoietic stem cell transplantation in humans: never say never again
inferredcites →https://doi.org/10.1111/j.1600-065x.2010.00964.xopenalex-snapshot
Multilayered specification of the T‐cell lineage fate
inferredcites →https://doi.org/10.1126/science.1218004openalex-snapshot
Interleukin-22 Drives Endogenous Thymic Regeneration in Mice
inferredcites →https://doi.org/10.1136/jcp.2010.086595openalex-snapshot
Osteoprotegerin, RANKL and bone turnover in postmenopausal osteoporosis
inferredcites →https://doi.org/10.1172/jci38052openalex-snapshot
Enhanced T cell recovery in HIV-1–infected adults through IL-7 treatment
inferredcites →https://doi.org/10.1172/jci81229openalex-snapshot
Outcomes of acute leukemia patients transplanted with naive T cell–depleted stem cell grafts
inferredcites →https://doi.org/10.1182/blood-2002-08-2671openalex-snapshot
Interleukin-7 improves CD4 T-cell reconstitution after autologous CD34 cell transplantation in monkeys
inferredcites →https://doi.org/10.1182/blood-2004-05-1687openalex-snapshot
Donor-derived IL-15 is critical for acute allogeneic graft-versus-host disease
inferredcites →https://doi.org/10.1182/blood-2006-02-001909openalex-snapshot
Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation
inferredcites →https://doi.org/10.1182/blood-2006-10-049767openalex-snapshot
Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells
inferredcites →https://doi.org/10.1182/blood-2007-08-104471openalex-snapshot
A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique
inferredcites →https://doi.org/10.1182/blood-2008-04-153627openalex-snapshot
CCL25 increases thymopoiesis after androgen withdrawal
inferredcites →https://doi.org/10.1182/blood-2008-09-177923openalex-snapshot
Long-term outcome after hematopoietic stem cell transplantation of a single-center cohort of 90 patients with severe combined immunodeficiency
inferredcites →https://doi.org/10.1182/blood-2011-02-334623openalex-snapshot
Thymic T-cell development in allogeneic stem cell transplantation
inferredcites →https://doi.org/10.1182/blood-2012-06-437236openalex-snapshot
Recombinant human interleukin-7 (CYT107) promotes T-cell recovery after allogeneic stem cell transplantation
inferredcites →https://doi.org/10.1182/blood-2014-12-616003openalex-snapshot
Faster T-cell development following gene therapy compared with haploidentical HSCT in the treatment of SCID-X1
inferredcites →https://doi.org/10.1182/blood-2015-02-628354openalex-snapshot
Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation
inferredcites →https://doi.org/10.1182/blood-2016-01-628982openalex-snapshot
T cells for viral infections after allogeneic hematopoietic stem cell transplant
inferredcites →https://doi.org/10.1182/blood-2017-01-762658openalex-snapshot
Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease
inferredcites →https://doi.org/10.1182/blood-2017-04-779769openalex-snapshot
Outcome of children with acute leukemia given HLA-haploidentical HSCT after αβ T-cell and B-cell depletion
inferredcites →https://doi.org/10.1182/blood-2018-03-840702openalex-snapshot
SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery
inferredcites →https://doi.org/10.1182/blood.v122.21.157.157openalex-snapshot
Removal Of Alpha/Beta+ T Cells and Of CD19+ B Cells From The Graft Translates Into Rapid Engraftment, Absence Of Visceral Graft-Versus-Host Disease and Low Transplant-Related Mortality In Children With Acute Leukemia Given HLA-Haploidentical Hematopoietic Stem Cell Transplantation
inferredcites →https://doi.org/10.1182/blood.v122.21.692.692openalex-snapshot
Transplantation Of TcRαβ/CD19 Depleted Stem Cells From Haploidentical Donors In Children: Current Results
inferredcites →https://doi.org/10.1182/blood.v124.21.1109.1109openalex-snapshot
CMV~IMPACT: Results of a Randomized Controlled Trial of Immuno-Prophylactic Adoptive Cellular Therapy following Sibling Donor Allogeneic HSCT
inferredcites →https://doi.org/10.1182/blood.v74.6.2237.2237openalex-snapshot
Graft failure after T-cell-depleted human leukocyte antigen identical marrow transplants for leukemia: II. In vitro analyses of host effector mechanisms
inferredcites →https://doi.org/10.1182/blood.v75.3.555.555openalex-snapshot
Graft-versus-leukemia reactions after bone marrow transplantation
inferredcites →https://doi.org/10.1182/blood.v76.12.2462.2462openalex-snapshot
Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients
inferredcites →https://doi.org/10.1182/blood.v90.12.4705openalex-snapshot
Allogeneic Peripheral Blood Stem Cell Transplantation May Be Associated With a High Risk of Chronic Graft-Versus-Host Disease
inferredcites →https://doi.org/10.1182/blood.v97.2.383openalex-snapshot
The number of donor CD3+ cells is the most important factor for graft failure after allogeneic transplantation of CD34+ selected cells from peripheral blood from HLA-identical siblings
inferredcites →https://doi.org/10.1182/blood.v97.6.1525openalex-snapshot
Interleukin-7 restores immunity in athymic T-cell–depleted hosts
inferredcites →https://doi.org/10.1182/bloodadvances.2017012724openalex-snapshot
Human herpesvirus 6 viremia affects T-cell reconstitution after allogeneic hematopoietic stem cell transplantation
inferredcites →https://doi.org/10.1200/jco.2017.73.0655openalex-snapshot
Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation
inferredcites →https://doi.org/10.1371/journal.pone.0082998openalex-snapshot
Recombinant IL-7/HGFβ Hybrid Cytokine Enhances T Cell Recovery in Mice Following Allogeneic Bone Marrow Transplantation
inferredcites →https://doi.org/10.1371/journal.pone.0091492openalex-snapshot
CXCR4-Related Increase of Circulating Human Lymphoid Progenitors after Allogeneic Hematopoietic Stem Cell Transplantation
inferredcites →https://doi.org/10.15252/emmm.201607176openalex-snapshot
Administration of RANKL boosts thymic regeneration upon bone marrow transplantation
inferredcites →https://doi.org/10.3389/fimmu.2013.00054openalex-snapshot
Thymic function recovery after unrelated donor cord blood or T-cell depleted HLA-haploidentical stem cell transplantation correlates with leukemia relapse
inferredcites →https://doi.org/10.4049/jimmunol.0900196openalex-snapshot
Sex Steroid Ablation Enhances Hematopoietic Recovery following Cytotoxic Antineoplastic Therapy in Aged Mice
inferredcites →https://doi.org/10.4049/jimmunol.1601100openalex-snapshot
Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation: Time To T Up the Thymus
inferredcites →https://doi.org/10.4049/jimmunol.177.1.169openalex-snapshot
Leptin Selectively Augments Thymopoiesis in Leptin Deficiency and Lipopolysaccharide-Induced Thymic Atrophy
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4005580openalex-extracted
The Establishment of a CMV-Specific CD8 + T-Cell Threshold by Kinetic Modelling for Prediction of Post-HSCT Reactivation
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110998openalex-snapshot
A research on the influence of G-CSF mobilization on donor's peripheral blood MDSCs and its relationship with patient prognosis
inferred← citeshttps://doi.org/10.1016/j.isci.2022.105340openalex-snapshot
The establishment of a cytomegalovirus -specific CD8+ T-cell threshold by kinetic modeling for the prediction of post-hemopoietic stem cell transplant reactivation
inferred← citeshttps://doi.org/10.1016/j.jtct.2025.11.039openalex-snapshot
Decitabine Conditioning Improves Natural Killer Cell Maturation and Limits CD8+ T Cell Terminal Differentiation Post-Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia Patients
inferred← citeshttps://doi.org/10.1038/s41409-022-01751-1openalex-snapshot
Donor genetic determinant of thymopoiesis rs2204985 impacts clinical outcome after single HLA mismatched hematopoietic stem cell transplantation
inferred← citeshttps://doi.org/10.1080/08820139.2025.2568871openalex-snapshot
PD-1/TIM-3–Expressing Myeloid Cells During the Early Immune Reconstitution in Patients with Multiple Myeloma After High-Dose Chemotherapy
inferred← citeshttps://doi.org/10.1097/md.0000000000033170openalex-snapshot
Comparison of oral zinc supplement and placebo effect in improving the T-cells regeneration in patients undergoing autologous hematopoietic stem cell transplantation: Clinical trial study
inferred← citeshttps://doi.org/10.1146/annurev-immunol-102119-073227openalex-snapshot
Current Concepts and Advances in Graft-Versus-Host Disease Immunology
inferred← citeshttps://doi.org/10.1172/jci.insight.157015openalex-snapshot
A Notch/IL-21 signaling axis primes bone marrow T cell progenitor expansion
inferred← citeshttps://doi.org/10.1177/09636897221079739openalex-snapshot
Lower Absolute Lymphocyte Count Before Conditioning Predicts High Relapse Risk in Patients After Haploidentical Peripheral Blood Stem Cell Transplantation With Low Dose Anti-Thymocyte Globulin/Post-Transplant Cyclophosphamide for GvHD Prophylaxis
inferred← citeshttps://doi.org/10.1182/bloodadvances.2025016915openalex-snapshot
Harmonized immune recovery monitoring after HCT: evidence and practical guidance from the Westhafen Intercontinental Group
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2408471/v1openalex-snapshot
Effect of zinc on the T cells reconstitution after autologous hematopoietic stem cell transplantation: a study protocol
inferred← citeshttps://doi.org/10.3389/fimmu.2020.01341openalex-snapshot
Evaluating Thymic Function After Human Hematopoietic Stem Cell Transplantation in the Personalized Medicine Era
inferred← citeshttps://doi.org/10.3389/fimmu.2020.567423openalex-snapshot
Considerations in Preparative Regimen Selection to Minimize Rejection in Pediatric Hematopoietic Transplantation in Non-Malignant Diseases
inferred← citeshttps://doi.org/10.3389/fimmu.2021.674093openalex-snapshot
Immune Reconstitution in the Aging Host: Opportunities for Mechanism-Based Therapy in Allogeneic Hematopoietic Cell Transplantation
inferred← citeshttps://doi.org/10.3389/fped.2021.786017openalex-snapshot
Immune Reconstitution After Allogeneic Haematopoietic Cell Transplantation: From Observational Studies to Targeted Interventions
inferred← citeshttps://doi.org/10.3390/diagnostics14222523openalex-snapshot
Cytomegalovirus Infections in Hematopoietic Stem Cell Transplant: Moving Beyond Molecular Diagnostics to Immunodiagnostics
inferred← citeshttps://doi.org/10.3390/ijms232213697openalex-snapshot
Synthesis of an Anti-CD7 Recombinant Immunotoxin Based on PE24 in CHO and E. coli Cell-Free Systems
inferred← citeshttps://doi.org/10.3390/vaccines13040397openalex-snapshot
Vaccinations in Pediatric Hematology and Oncology: Biologic Basis, Clinical Applications, and Perspectives
inferred← citeshttps://doi.org/10.37349/ei.2022.00041openalex-snapshot
The role of γδ T cells in the context of allogeneic stem cell transplantation
inferred← citeshttps://doi.org/10.3892/ijmm.2020.4657openalex-snapshot
Co‑transplantation of tonsil‑derived mesenchymal stromal cells in bone marrow transplantation promotes thymus regeneration and T cell diversity following cytotoxic conditioning
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