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Candidate biomarkers in psychiatric disorders: state of the field

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Phenotyping extracellular vesicles and their serotonin transporter cargo in major depressive disorder

inferred← citeshttps://doi.org/10.1016/j.jad.2025.120194openalex-snapshot

Predictive and mechanistic biomarkers of treatment response to Transcranial Magnetic Stimulation (TMS) in Psychiatric and Neurocognitive Disorders, identified via TMS-Electroencephalography (EEG) and Resting-State EEG: A systematic review

inferred← citeshttps://doi.org/10.1016/j.jad.2025.121096openalex-snapshot

Development and validation of machine learning models to predict PTSD at multiple time points in hospitalized trauma patients

inferred← citeshttps://doi.org/10.1016/j.jad.2026.121586openalex-snapshot

Multi-omics analysis reveals CXCL14+ inhibitory neuron dysfunction in major depressive disorder

inferred← citeshttps://doi.org/10.1016/j.jad.2026.122108openalex-snapshot

Allostatic load as a moderating factor between child maltreatment exposure and mental health challenges in children and adolescents: a study based on the EPI_Young_Stress Project

inferred← citeshttps://doi.org/10.1016/j.jad.2026.122323openalex-snapshot

Multimodal physiological responses evoked by emotional naturalistic stimuli facilitate classification of major depression and generalized anxiety

inferred← citeshttps://doi.org/10.1016/j.jad.2026.122485openalex-snapshot

Altered cortical oxygenation dynamics, impaired cortical recruitment, and network dysconnectivity across the transdiagnostic anxiety spectrum: a systems biology multi-channel fNIRS study

inferred← citeshttps://doi.org/10.1016/j.jagp.2025.05.005openalex-snapshot

Can Artificial Intelligence be Used to Design More Ecologically Valid Mental Health Scales for Older People?

inferred← citeshttps://doi.org/10.1016/j.jagp.2026.04.001openalex-snapshot

Toward Precision Diagnosis of Late-Life Mood Disorders: A Neuropathology-Informed Framework and Research Agenda

inferred← citeshttps://doi.org/10.1016/j.jestch.2025.102116openalex-snapshot

EEG-SymNet: multi-channel EEG signal-based schizophrenia diagnosis using channel recalibration and symmetric spatial temporal transformer network

inferred← citeshttps://doi.org/10.1016/j.jpha.2025.101264openalex-snapshot

Biomarkers of bipolar disorder in omics and neuroimaging

inferred← citeshttps://doi.org/10.1016/j.jpsychires.2024.04.040openalex-snapshot

The relationship between anxiety symptoms and disturbances in biological rhythms in patients with depression

inferred← citeshttps://doi.org/10.1016/j.jpsychires.2025.01.037openalex-snapshot

Clinical studies of blood-borne Extracellular vesicles in psychiatry: A systematic review

inferred← citeshttps://doi.org/10.1016/j.jpsychires.2025.08.016openalex-snapshot

Predicting the longitudinal efficacy of medication for depression using electroencephalography and machine learning

inferred← citeshttps://doi.org/10.1016/j.jpsychires.2025.10.004openalex-snapshot

Diagnostic performance of T1-Weighted MRI in bipolar disorder: A systematic review and meta-analysis

inferred← citeshttps://doi.org/10.1016/j.jpsychires.2026.04.021openalex-snapshot

Cerebral metabolism as an isolated predictor of 50% symptomatic improvement over 12 weeks of acute psychotic episode treatment in schizophrenia

inferred← citeshttps://doi.org/10.1016/j.jpsychires.2026.05.038openalex-snapshot

Cross-sectional and prospective analysis of the association of the pupillary light reflex with suicidal ideation and suicide attempts

inferred← citeshttps://doi.org/10.1016/j.jpsychores.2025.112340openalex-snapshot

Mental health risks associated with a family history of chronic diseases: A nationwide population-based cross-sectional study

inferred← citeshttps://doi.org/10.1016/j.jrras.2026.102245openalex-snapshot

Enhancing the early diagnosis of bipolar disorder with machine learning models

inferred← citeshttps://doi.org/10.1016/j.metrad.2025.100135openalex-snapshot

Rethinking the studies of diagnostic biomarkers for mental disorders

inferred← citeshttps://doi.org/10.1016/j.neubiorev.2024.105599openalex-snapshot

An evolutionary analysis of the applicability and utility of the clinico-pathological method in psychiatry

inferred← citeshttps://doi.org/10.1016/j.neubiorev.2025.106320openalex-snapshot

Obsessive-compulsive disorder – A state-of-the-art review

inferred← citeshttps://doi.org/10.1016/j.neubiorev.2025.106325openalex-snapshot

Psychiatric comorbidity in substance use disorders, a systematic review of neuro-imaging findings

inferred← citeshttps://doi.org/10.1016/j.neumar.2025.100040openalex-snapshot

Neurobiomarkers of psychiatric disorders in children and adolescents and their significance for diagnosis and precision medicine: A narrative review

inferred← citeshttps://doi.org/10.1016/j.neumar.2025.100127openalex-snapshot

Translational potential of RNA biomarkers in mental health: A narrative review

inferred← citeshttps://doi.org/10.1016/j.neumar.2025.100144openalex-snapshot

Neuromarkers in bipolar disorder: A narrative review bridging neuroscience and clinical practice

inferred← citeshttps://doi.org/10.1016/j.neumar.2025.100150openalex-snapshot

Neurobiological and neuroimaging biomarkers: A narrative review of precision medicine for diagnosing neurodegenerative disorders

inferred← citeshttps://doi.org/10.1016/j.neunet.2025.107209openalex-snapshot

Multimodal cross-scale context clusters for classification of mental disorders using functional and structural MRI

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2024.120839openalex-snapshot

Local-structure-preservation and redundancy-removal-based feature selection method and its application to the identification of biomarkers for schizophrenia

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2025.121422openalex-snapshot

Discovering robust biomarkers of psychiatric disorders from resting-state functional MRI via graph neural networks: A systematic review

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2026.122127openalex-snapshot

Visual cortical plasticity depends on stimulus structure and temporal dynamics

inferred← citeshttps://doi.org/10.1016/j.neuropharm.2024.110057openalex-snapshot

Reversal of electrophysiological and behavioral deficits mediated by 5-HT7 receptor upregulation following LP-211 treatment in an autistic-like rat model induced by prenatal valproic acid exposure

inferred← citeshttps://doi.org/10.1016/j.nicl.2025.103874openalex-snapshot

Brain changes associated with depression treatment: a meta-analysis

inferred← citeshttps://doi.org/10.1016/j.nsa.2023.103932openalex-snapshot

Anxiety in post-covid-19 syndrome – prevalence, mechanisms and treatment

inferred← citeshttps://doi.org/10.1016/j.nupsyc.2026.100031openalex-snapshot

Zinc and B6 supplementation for the management of acute symptoms of self-reported generalized anxiety: a pilot double blind randomised placebo-controlled trial, including an exploration of a potential kryptopyrrole urinary biomarker

inferred← citeshttps://doi.org/10.1016/j.parkreldis.2026.108363openalex-snapshot

Amplitude of low-frequency fluctuation differences in resting-state functional magnetic resonance imaging between Parkinson's disease and multiple system atrophy-parkinsonian type

inferred← citeshttps://doi.org/10.1016/j.pmip.2024.100118openalex-snapshot

Beyond one-size-fits-all: The rise of personalized treatment in schizophrenia

inferred← citeshttps://doi.org/10.1016/j.pmip.2025.100155openalex-snapshot

Neurobiology and behavior associated with early neglect: An exploratory comparison of neglected US children and international adoptees

inferred← citeshttps://doi.org/10.1016/j.pnpbp.2026.111761openalex-snapshot

Neurophysiological markers of GABAergic and glutamatergic function associated with childhood adversity in adolescent depression: An exploratory transcranial magnetic stimulation study

inferred← citeshttps://doi.org/10.1016/j.psc.2025.12.002openalex-snapshot

Disorders of Mood and Affect

inferred← citeshttps://doi.org/10.1016/j.psychres.2025.116828openalex-snapshot

Individual alpha peak predicts clinical response in TMS therapy for depression: An independent replication

inferred← citeshttps://doi.org/10.1016/j.psychres.2026.117002openalex-snapshot

Medical intelligence vs. artificial intelligence — How psychiatrists arrive at treatment algorithms

inferred← citeshttps://doi.org/10.1016/j.psychres.2026.117227openalex-snapshot

PyramidPat explainable feature engineering for multiclass electroencephalography psychiatric disorders: Explainable feature engineering and classification

inferred← citeshttps://doi.org/10.1016/j.psychres.2026.117327openalex-snapshot

Peripheral serotonin–kynurenine pathway alterations and their associations with symptom severity in post-traumatic stress disorder: An exploratory case–control study

inferred← citeshttps://doi.org/10.1016/j.psyneuen.2025.107684openalex-snapshot

Demonstrating the potential of untargeted hair proteomics for personalized biomarkers in stress-associated disorders

inferred← citeshttps://doi.org/10.1016/j.ridd.2026.105360openalex-snapshot

Criterion A in developmental coordination disorder: Is motor competence efficiently assessed? A systematic review and meta-analysis of mixed evidence from standardized assessments

inferred← citeshttps://doi.org/10.1016/j.schres.2024.03.011openalex-snapshot

Inflammatory blood cells and ratios at remission for psychosis relapse prediction: A three-year follow-up of a cohort of first episodes of schizophrenia

inferred← citeshttps://doi.org/10.1016/j.schres.2025.05.026openalex-snapshot

Molecular signatures and emerging therapeutic targets in schizophrenia: A biomarker-centric perspective in psychiatric disorders

inferred← citeshttps://doi.org/10.1016/j.schres.2025.12.005openalex-snapshot

Comparative lipidomic alterations in the anterior cingulate cortex in schizophrenia and major depression

inferred← citeshttps://doi.org/10.1016/j.schres.2026.03.001openalex-snapshot

Reframing schizophrenia as a neurodevelopmental syndrome: The scientific and social imperative

inferred← citeshttps://doi.org/10.1016/j.sjpmh.2025.12.001openalex-snapshot

From biomarkers to care: integrating biology and clinical translation in psychiatry

inferred← citeshttps://doi.org/10.1016/j.sjpmh.2026.02.006openalex-snapshot

Blood-based immune biomarkers and functional outcomes in acute schizophrenia: A retrospective cohort study

inferred← citeshttps://doi.org/10.1016/j.smrv.2025.102099openalex-snapshot

Connecting mechanistic evidence for depression, anxiety, and insomnia with neuroimaging

inferred← citeshttps://doi.org/10.1016/j.xcrm.2026.102780openalex-snapshot

Microbiome biomarkers in autism spectrum disorder: Toward prediction, diagnosis, and prognosis

inferred← citeshttps://doi.org/10.1016/j.xpro.2025.104276openalex-snapshot

Protocol to investigate neurophysiological link between resting-state brain activity and clinical symptoms in methamphetamine use disorder

inferred← citeshttps://doi.org/10.1016/j.ymeth.2026.01.001openalex-snapshot

ERAPID: an end‑to‑end RNA‑seq analysis pipeline for integrative candidate biomarker discovery with applications to neuropsychiatric disorders

inferred← citeshttps://doi.org/10.1016/s2215-0366(26)00267-1openalex-snapshot

From discovery to proof: a Translation Evidence Map for precision psychiatry

inferred← citeshttps://doi.org/10.1017/s003329172400223xopenalex-snapshot

New diagnosis in psychiatry: beyond heuristics

inferred← citeshttps://doi.org/10.1017/s0033291724003374openalex-snapshot

Persistent PTSD symptoms are associated with plasma metabolic alterations relevant to long-term health: A metabolome-wide investigation in women

inferred← citeshttps://doi.org/10.1017/s0033291726103511openalex-snapshot

Identification of a diagnosis-selective neurobiological substrate for bipolar disorder, major depressive disorder, and schizophrenia: a meta-analysis of 57,717 subjects

inferred← citeshttps://doi.org/10.1021/acs.chemrev.4c00244openalex-snapshot

Aggregation-Induced Emission Luminogen: Role in Biopsy for Precision Medicine

inferred← citeshttps://doi.org/10.1021/acs.jproteome.4c00389openalex-snapshot

Using Data-Driven Algorithms with Large-Scale Plasma Proteomic Data to Discover Novel Biomarkers for Diagnosing Depression

inferred← citeshttps://doi.org/10.1021/acssensors.4c00322openalex-snapshot

Sensitivity-Enhancing Strategies of Graphene Field-Effect Transistor Biosensors for Biomarker Detection

inferred← citeshttps://doi.org/10.1026/0012-1924/a000369openalex-snapshot

EEG Biomarkers as Indices of Functional Brain Systems in Child and Adolescent Psychiatry

inferred← citeshttps://doi.org/10.1038/s41380-023-02381-9openalex-snapshot

Replication of a neuroimaging biomarker for striatal dysfunction in psychosis

inferred← citeshttps://doi.org/10.1038/s41380-024-02767-3openalex-snapshot

Functional dysconnectivity of visual and somatomotor networks yields a simple and robust biomarker for psychosis

inferred← citeshttps://doi.org/10.1038/s41380-025-03038-5openalex-snapshot

Epigenetic markers of disease risk and psychotherapy response in anxiety disorders – a longitudinal analysis of the DNA methylome

inferred← citeshttps://doi.org/10.1038/s41380-025-03134-6openalex-snapshot

Computational mechanisms of neuroimaging biomarkers uncovered by multicenter resting-state fMRI connectivity variation profile

inferred← citeshttps://doi.org/10.1038/s41380-025-03157-zopenalex-snapshot

Longitudinal multi-omics analysis of umbilical cord blood and childhood serum in Autism

inferred← citeshttps://doi.org/10.1038/s41380-025-03297-2openalex-snapshot

Cognitive arbitration between candidate dimensions of psychopathology

inferred← citeshttps://doi.org/10.1038/s41380-026-03883-yopenalex-snapshot

Natural anti–NMDAR1 autoantibodies are associated with lower risk for depression and PTSD symptoms after traumatic brain injury

inferred← citeshttps://doi.org/10.1038/s41386-025-02079-2openalex-snapshot

Persistent brain network signatures in psychosis: implications for diagnosis, prognosis, and treatment

inferred← citeshttps://doi.org/10.1038/s41386-025-02182-4openalex-snapshot

Integration of developmental and socio-cultural factors that confer risk for mental illness

inferred← citeshttps://doi.org/10.1038/s41398-024-02948-2openalex-snapshot

ProMENDA: an updated resource for proteomic and metabolomic characterization in depression

inferred← citeshttps://doi.org/10.1038/s41398-025-03433-0openalex-snapshot

Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech

inferred← citeshttps://doi.org/10.1038/s41398-025-03676-xopenalex-snapshot

Development of VEP-based biomarkers to assess plasticity states

inferred← citeshttps://doi.org/10.1038/s41398-025-03703-xopenalex-snapshot

rbfox1 LoF mutants show disrupted bdnf/trkb2 and crhb/nr3c2 expression and increased cortisol levels during development coupled with signs of allostatic overload in adulthood

inferred← citeshttps://doi.org/10.1038/s41398-026-03938-2openalex-snapshot

ADHD polygenic risk predicts neural signatures of cognitive control: Evidence from midfrontal theta dynamics

inferred← citeshttps://doi.org/10.1038/s41398-026-03939-1openalex-snapshot

Prospective biomarkers of posttraumatic stress disorder in children and adolescents: a systematic review and meta-analysis

inferred← citeshttps://doi.org/10.1038/s41398-026-04055-wopenalex-snapshot

Diminished variability of alpha and beta band-limited power as a neural signature in schizophrenia

inferred← citeshttps://doi.org/10.1038/s41398-026-04058-7openalex-snapshot

Serum metabolites associated with depression and anxiety in the Hispanic Community Health Study/Study of Latinos

inferred← citeshttps://doi.org/10.1038/s41398-026-04333-7openalex-snapshot

Cardiac vagal activity during in-vivo threat exposure is associated with within-session inhibition of fear and avoidance

inferred← citeshttps://doi.org/10.1038/s41537-025-00686-yopenalex-snapshot

Why is schizophrenia a huge graveyard of molecules?

inferred← citeshttps://doi.org/10.1038/s41572-023-00454-1openalex-snapshot

Major depressive disorder

inferred← citeshttps://doi.org/10.1038/s41586-023-06670-9openalex-snapshot

Functional neuroimaging as a catalyst for integrated neuroscience

inferred← citeshttps://doi.org/10.1038/s41597-025-04384-3openalex-snapshot

OBF-Psychiatric, a motor activity dataset of patients diagnosed with major depression, schizophrenia, and ADHD

inferred← citeshttps://doi.org/10.1038/s41598-023-46401-8openalex-snapshot

Association of granulocyte macrophage colony-stimulating factor and interleukin-17 levels with obsessive–compulsive disorder: a case–control study findings

inferred← citeshttps://doi.org/10.1038/s41598-024-64299-8openalex-snapshot

ASD-SWNet: a novel shared-weight feature extraction and classification network for autism spectrum disorder diagnosis

inferred← citeshttps://doi.org/10.1038/s41598-024-83375-7openalex-snapshot

On the improvement of schizophrenia detection with optical coherence tomography data using deep neural networks and aggregation functions

inferred← citeshttps://doi.org/10.1038/s41598-025-01499-wopenalex-snapshot

Canonical correlation analysis of anxiety symptom and behavioral inhibition/activation system among college students and their relationship with physical activity

inferred← citeshttps://doi.org/10.1038/s41598-025-89580-2openalex-snapshot

Combined loss of brevican, neurocan, tenascin-C and tenascin-R leads to impaired fear retrieval due to perineuronal net loss

inferred← citeshttps://doi.org/10.1038/s41598-025-91294-4openalex-snapshot

The mediating role of behavioral systems in linking physical activity and anxiety symptoms in college students

inferred← citeshttps://doi.org/10.1038/s41598-026-48501-7openalex-snapshot

Judgment behaviors differentiate depression from anxiety

inferred← citeshttps://doi.org/10.1038/s41598-026-57667-zopenalex-snapshot

Decision processes in 3D structural MRI schizophrenia classification evaluated with saliency maps

inferred← citeshttps://doi.org/10.1038/s41746-025-02194-wopenalex-snapshot

Diagnostic digital phenotyping in schizophrenia-spectrum disorders: a systematic review

inferred← citeshttps://doi.org/10.1038/s41746-026-02550-4openalex-snapshot

Deep learning characterizes depression and suicidal ideation in young adults from eye movements

inferred← citeshttps://doi.org/10.1038/s44159-024-00357-2openalex-snapshot

Federal funding shapes knowledge in clinical science

inferred← citeshttps://doi.org/10.1038/s44159-024-00362-5openalex-snapshot

Revisiting the use of adverse childhood experience screening in healthcare settings

inferred← citeshttps://doi.org/10.1038/s44220-025-00422-6openalex-snapshot

Brain and body energy metabolism and potential for treatment of psychiatric disorders

inferred← citeshttps://doi.org/10.1038/s44277-026-00069-wopenalex-snapshot

Toward actionable biomarkers in psychiatry: a collaborative roadmap for precision clinical trials. An ACNP position paper

inferred← citeshttps://doi.org/10.1051/bioconf/202625204001openalex-snapshot

Exploring naringenin-clozapine combination for synergistic antipsychotic action: An in-silico study

inferred← citeshttps://doi.org/10.1051/medsci/2025061openalex-snapshot

Imagerie cérébrale et premiers succès de la psychiatrie de précision

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