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Novel Treatment Approaches for Brain Tumour from a Blood–Brain Barrier Perspective

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015
inferredcites →https://doi.org/10.1002/ijc.22732openalex-snapshot
Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI‐guided focused ultrasound
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Microvessel Organization and Structure in Experimental Brain Tumors: Microvessel Populations with Distinctive Structural and Functional Properties
inferredcites →https://doi.org/10.1007/978-3-540-46091-6_10openalex-snapshot
Targeted Therapy and Blood-Brain Barrier
inferredcites →https://doi.org/10.1007/s00280-014-2490-0openalex-snapshot
Irinotecan and temozolomide brain distribution: a focus on ABCB1
inferredcites →https://doi.org/10.1007/s00401-012-1066-5openalex-snapshot
Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited
inferredcites →https://doi.org/10.1007/s00441-008-0658-9openalex-snapshot
Brain endothelial cells and the glio-vascular complex
inferredcites →https://doi.org/10.1007/s11060-010-0255-0openalex-snapshot
Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study
inferredcites →https://doi.org/10.1007/s11060-015-1724-2openalex-snapshot
Survival outcomes and safety of carmustine wafers in the treatment of high-grade gliomas: a meta-analysis
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Mechanisms of Glioma-Associated Neovascularization
inferredcites →https://doi.org/10.1016/j.biomaterials.2012.04.048openalex-snapshot
Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model
inferredcites →https://doi.org/10.1016/j.ctrv.2004.04.001openalex-snapshot
Modulation of the blood–brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?
inferredcites →https://doi.org/10.1016/j.ctrv.2013.11.010openalex-snapshot
Recent developments and current concepts in medulloblastoma
inferredcites →https://doi.org/10.1016/j.drudis.2008.09.005openalex-snapshot
The targeted delivery of cancer drugs across the blood–brain barrier: chemical modifications of drugs or drug-nanoparticles?
inferredcites →https://doi.org/10.1016/j.drup.2015.02.002openalex-snapshot
Overcoming the blood–brain tumor barrier for effective glioblastoma treatment
inferredcites →https://doi.org/10.1016/j.ejmech.2018.12.033openalex-snapshot
Recent advances in the discovery of small molecules targeting glioblastoma
inferredcites →https://doi.org/10.1016/j.ijpharm.2012.06.025openalex-snapshot
Drug delivery strategies for the treatment of malignant gliomas
inferredcites →https://doi.org/10.1016/j.jconrel.2014.05.033openalex-snapshot
Prolonged survival upon ultrasound-enhanced doxorubicin delivery in two syngenic glioblastoma mouse models
inferredcites →https://doi.org/10.1016/j.jconrel.2016.01.054openalex-snapshot
Lauroyl-gemcitabine-loaded lipid nanocapsule hydrogel for the treatment of glioblastoma
inferredcites →https://doi.org/10.1016/j.jconrel.2018.05.005openalex-snapshot
Brainstem blood brain barrier disruption using focused ultrasound: A demonstration of feasibility and enhanced doxorubicin delivery
inferredcites →https://doi.org/10.1016/j.nbd.2003.12.016openalex-snapshot
The blood–brain barrier: an overview
inferredcites →https://doi.org/10.1016/j.nbd.2009.07.030openalex-snapshot
Structure and function of the blood–brain barrier
inferredcites →https://doi.org/10.1016/j.neuroimage.2019.06.060openalex-snapshot
Resting state functional connectivity changes after MR-guided focused ultrasound mediated blood-brain barrier opening in patients with Alzheimer's disease
inferredcites →https://doi.org/10.1016/j.neuron.2008.01.003openalex-snapshot
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
inferredcites →https://doi.org/10.1016/j.nurt.2009.04.004openalex-snapshot
Novel Drug Delivery Strategies in Neuro-Oncology
inferredcites →https://doi.org/10.1016/j.ultrasmedbio.2007.11.009openalex-snapshot
Effects of Acoustic Parameters and Ultrasound Contrast Agent Dose on Focused-Ultrasound Induced Blood-Brain Barrier Disruption
inferredcites →https://doi.org/10.1016/j.ultrasmedbio.2007.12.015openalex-snapshot
Effect of Focused Ultrasound Applied With an Ultrasound Contrast Agent on the Tight Junctional Integrity of the Brain Microvascular Endothelium
inferredcites →https://doi.org/10.1016/j.ultrasmedbio.2012.04.015openalex-snapshot
Improved Anti-Tumor Effect of Liposomal Doxorubicin After Targeted Blood-Brain Barrier Disruption by MRI-Guided Focused Ultrasound in Rat Glioma
inferredcites →https://doi.org/10.1016/s0344-0338(98)80015-0openalex-snapshot
Multidrug Resistance in Glioblastoma
inferredcites →https://doi.org/10.1016/s1474-4422(10)70181-2openalex-snapshot
Advanced MRI and PET imaging for assessment of treatment response in patients with gliomas
inferredcites →https://doi.org/10.1016/s1537-1891(02)00200-8openalex-snapshot
Tight junctions of the blood-brain barrier: development, composition and regulation.
inferredcites →https://doi.org/10.1021/mp3003144openalex-snapshot
Oral Availability and Brain Penetration of the B-RAF V600E Inhibitor Vemurafenib Can Be Enhanced by the P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) Inhibitor Elacridar
inferredcites →https://doi.org/10.1038/bjc.1997.408openalex-snapshot
Murine P-glycoprotein on stromal vessels mediates multidrug resistance in intracerebral human glioma xenografts
inferredcites →https://doi.org/10.1038/ncomms5196openalex-snapshot
Disruption of astrocyte–vascular coupling and the blood–brain barrier by invading glioma cells
inferredcites →https://doi.org/10.1038/nm.3407openalex-snapshot
Development, maintenance and disruption of the blood-brain barrier
inferredcites →https://doi.org/10.1038/nn.4288openalex-snapshot
Pericytes of the neurovascular unit: key functions and signaling pathways
inferredcites →https://doi.org/10.1038/nrclinonc.2011.58openalex-snapshot
The biology of brain metastases—translation to new therapies
inferredcites →https://doi.org/10.1038/nrn1824openalex-snapshot
Astrocyte–endothelial interactions at the blood–brain barrier
inferredcites →https://doi.org/10.1038/s41467-019-12426-9openalex-snapshot
First-in-human trial of blood–brain barrier opening in amyotrophic lateral sclerosis using MR-guided focused ultrasound
inferredcites →https://doi.org/10.1038/s41568-019-0205-xopenalex-snapshot
The blood–brain barrier and blood–tumour barrier in brain tumours and metastases
inferredcites →https://doi.org/10.1038/s41598-018-30533-3openalex-snapshot
Whole-Brain Vasculature Reconstruction at the Single Capillary Level
inferredcites →https://doi.org/10.1038/s41598-018-36340-0openalex-snapshot
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study
inferredcites →https://doi.org/10.1038/sj.bjc.6690802openalex-snapshot
Phase I dose-escalation and pharmacokinetic study of temozolomide (SCH 52365) for refractory or relapsing malignancies
inferredcites →https://doi.org/10.1038/sj.jcbfm.9600336openalex-snapshot
Multiphoton Imaging of Ultrasound/Optison Mediated Cerebrovascular Effects in vivo
inferredcites →https://doi.org/10.1056/nejm198012043032303openalex-snapshot
Randomized Comparisons of Radiotherapy and Nitrosoureas for the Treatment of Malignant Glioma after Surgery
inferredcites →https://doi.org/10.1056/nejmoa043330openalex-snapshot
Radiotherapy Plus Concomitant and Adjuvant Temozolomide for Glioblastoma
inferredcites →https://doi.org/10.1073/pnas.89.18.8472openalex-snapshot
Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis.
inferredcites →https://doi.org/10.1080/00498250410001685737openalex-snapshot
Disposition and pharmacokinetics of temozolomide in rat
inferredcites →https://doi.org/10.1080/14737175.2016.1202761openalex-snapshot
Blood-brain barrier, cytotoxic chemotherapies and glioblastoma
inferredcites →https://doi.org/10.1083/jcb.151.5.f31openalex-snapshot
Tight Junction, a Platform for Trafficking and Signaling Protein Complexes
inferredcites →https://doi.org/10.1093/neuonc/2.1.45openalex-snapshot
The blood-brain and blood-tumor barriers: A review of strategies for increasing drug delivery
inferredcites →https://doi.org/10.1093/neuonc/5.2.79openalex-snapshot
A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma
inferredcites →https://doi.org/10.1093/neuonc/nop054openalex-snapshot
Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma
inferredcites →https://doi.org/10.1093/neuonc/nor054openalex-snapshot
Molecular imaging of gliomas with PET: Opportunities and limitations
inferredcites →https://doi.org/10.1093/neuonc/nov164openalex-snapshot
Strategies to improve delivery of anticancer drugs across the blood–brain barrier to treat glioblastoma
inferredcites →https://doi.org/10.1093/neuonc/nox175openalex-snapshot
Is the blood–brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data
inferredcites →https://doi.org/10.1093/neuonc/noy084openalex-snapshot
Immunotherapy in CNS cancers: the role of immune cell trafficking
inferredcites →https://doi.org/10.1097/00006123-199904000-00021openalex-snapshot
Supratentorial Ependymomas in Adult Patients
inferredcites →https://doi.org/10.1097/00006123-199904000-00022openalex-snapshot
Vascular Endothelial Growth Factor Expression, Vascular Volume, and Capillary Permeability in Human Brain Tumors
inferredcites →https://doi.org/10.1097/aln.0b013e31818d8f28openalex-snapshot
Tariquidar, a Selective P-glycoprotein Inhibitor, Does Not Potentiate Loperamide’s Opioid Brain Effects in Humans despite Full Inhibition of Lymphocyte P-glycoprotein
inferredcites →https://doi.org/10.1101/cshperspect.a020412openalex-snapshot
The Blood–Brain Barrier
inferredcites →https://doi.org/10.1111/j.1528-1167.2012.03702.xopenalex-snapshot
Inflammatory events at blood–brain barrier in neuroinflammatory and neurodegenerative disorders: Implications for clinical disease
inferredcites →https://doi.org/10.1124/dmd.112.049148openalex-snapshot
Tariquidar and Elacridar Are Dose-Dependently Transported by P-Glycoprotein and Bcrp at the Blood-Brain Barrier: A Small-Animal Positron Emission Tomography and In Vitro Study
inferredcites →https://doi.org/10.1126/scitranslmed.aaf6086openalex-snapshot
Clinical trial of blood-brain barrier disruption by pulsed ultrasound
inferredcites →https://doi.org/10.1148/radiol.2202001804openalex-snapshot
Noninvasive MR Imaging–guided Focal Opening of the Blood-Brain Barrier in Rabbits
inferredcites →https://doi.org/10.1152/ajpcell.00581.2004openalex-snapshot
Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells
inferredcites →https://doi.org/10.1152/physrev.1985.65.1.101openalex-snapshot
Effect of anoxia on ion distribution in the brain
inferredcites →https://doi.org/10.1155/2015/320941openalex-snapshot
Blood Brain Barrier: A Challenge for Effectual Therapy of Brain Tumors
inferredcites →https://doi.org/10.1155/2015/371905openalex-snapshot
The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study
inferredcites →https://doi.org/10.1158/1078-0432.ccr-06-2854openalex-snapshot
The Blood-Brain Barrier and Cancer: Transporters, Treatment, and Trojan Horses
inferredcites →https://doi.org/10.1158/1078-0432.ccr-15-1836openalex-snapshot
Alterations in Pericyte Subpopulations Are Associated with Elevated Blood–Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-18-3643openalex-snapshot
Safety and Feasibility of Repeated and Transient Blood–Brain Barrier Disruption by Pulsed Ultrasound in Patients with Recurrent Glioblastoma
inferredcites →https://doi.org/10.1186/1471-2377-9-s1-s3openalex-snapshot
Characteristics of compounds that cross the blood-brain barrier
inferredcites →https://doi.org/10.1186/1748-717x-9-25openalex-snapshot
Radiation therapy combined with intracerebral administration of carboplatin for the treatment of brain tumors
inferredcites →https://doi.org/10.1200/jco.2005.04.7233openalex-snapshot
Physiologic and Metabolic Magnetic Resonance Imaging in Gliomas
inferredcites →https://doi.org/10.1215/15228517-2006-016openalex-snapshot
Convection-enhanced delivery of a topoisomerase I inhibitor (nanoliposomal topotecan) and a topoisomerase II inhibitor (pegylated liposomal doxorubicin) in intracranial brain tumor xenografts1
inferredcites →https://doi.org/10.1215/s1522851799000307openalex-snapshot
The blood-brain and blood-tumor barriers: A review of strategies for increasing drug delivery
inferredcites →https://doi.org/10.1227/01.neu.0000363152.37594.f7openalex-snapshot
Intra-arterial chemotherapy with osmotic blood-brain barrier disruption for aggressive oligodendroglial tumors: results of a phase I study.
inferredcites →https://doi.org/10.1227/01.neu.0000365802.02410.c5openalex-snapshot
Occipitoatlantal Dislocation
inferredcites →https://doi.org/10.1371/journal.pone.0058995openalex-snapshot
Focused Ultrasound-Induced Blood–Brain Barrier Opening to Enhance Temozolomide Delivery for Glioblastoma Treatment: A Preclinical Study
inferredcites →https://doi.org/10.1371/journal.pone.0082331openalex-snapshot
Pharmacokinetics, Brain Delivery, and Efficacy in Brain Tumor-Bearing Mice of Glutathione Pegylated Liposomal Doxorubicin (2B3-101)
inferredcites →https://doi.org/10.1371/journal.pone.0114311openalex-snapshot
Pharmacodynamic and Therapeutic Investigation of Focused Ultrasound-Induced Blood-Brain Barrier Opening for Enhanced Temozolomide Delivery in Glioma Treatment
inferredcites →https://doi.org/10.1371/journal.pone.0166061openalex-snapshot
Effects on P-Glycoprotein Expression after Blood-Brain Barrier Disruption Using Focused Ultrasound and Microbubbles
inferredcites →https://doi.org/10.1586/14737140.2013.840090openalex-snapshot
The role of Gliadel wafers in the treatment of high-grade gliomas
inferredcites →https://doi.org/10.2174/156802607782194806openalex-snapshot
Mini Review on Molecular Modeling of P-Glycoprotein (Pgp)
inferredcites →https://doi.org/10.2174/157015908785777210openalex-snapshot
Brain Endothelial Cell-Cell Junctions: How to “Open” the Blood Brain Barrier
inferredcites →https://doi.org/10.2217/cns.15.2openalex-snapshot
Chemotherapy in glioma
inferredcites →https://doi.org/10.3171/2014.10.jns14229openalex-snapshot
Convection-enhanced delivery to the central nervous system
inferredcites →https://doi.org/10.3171/2014.12.focus14758openalex-snapshot
Therapeutic strategies to improve drug delivery across the blood-brain barrier
inferredcites →https://doi.org/10.3171/2015.1.focus14767openalex-snapshot
Novel delivery methods bypassing the blood-brain and blood-tumor barriers
inferredcites →https://doi.org/10.3171/2016.1.jns151591openalex-snapshot
Convection-enhanced delivery in glioblastoma: a review of preclinical and clinical studies
inferredcites →https://doi.org/10.3171/2019.10.jns192206openalex-snapshot
Safety and feasibility of multiple blood-brain barrier disruptions for the treatment of glioblastoma in patients undergoing standard adjuvant chemotherapy
inferredcites →https://doi.org/10.3171/jns.2000.92.4.0599openalex-snapshot
In vivo assessment of the window of barrier opening after osmotic blood—brain barrier disruption in humans
inferredcites →https://doi.org/10.3171/jns.2004.100.3.0472openalex-snapshot
Convection-enhanced delivery of paclitaxel for the treatment of recurrent malignant glioma: a Phase I/II clinical study
inferredcites →https://doi.org/10.3389/fncel.2014.00418openalex-snapshot
Gliomas and the vascular fragility of the blood brain barrier
inferredcites →https://doi.org/10.3389/fonc.2014.00126openalex-snapshot
Emerging Insights into Barriers to Effective Brain Tumor Therapeutics
inferredcites →https://doi.org/10.3390/pharmaceutics7030175openalex-snapshot
Neurosurgical Techniques for Disruption of the Blood–Brain Barrier for Glioblastoma Treatment
inferredcites →https://doi.org/10.35308/jns.v1i2.2757openalex-snapshot
Body Mass Index, Eating Habits and Physical Activity Among Dietetics Students in Universiti Sultan Zainal Abidin
inferredcites →https://doi.org/10.7150/thno.21630openalex-snapshot
Acute Inflammatory Response Following Increased Blood-Brain Barrier Permeability Induced by Focused Ultrasound is Dependent on Microbubble Dose
inferredcites →https://doi.org/10.7863/jum.2010.29.1.61openalex-snapshot
Antitumor Effect of Docetaxel-Loaded Lipid Microbubbles Combined With Ultrasound-Targeted Microbubble Activation on VX2 Rabbit Liver Tumors
inferredcites →https://doi.org/10.7863/ultra.16.02005openalex-snapshot
Blood‐Brain Barrier Closure Time After Controlled Ultrasound‐Induced Opening Is Independent of Opening Volume

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4661733openalex-extracted
Taking Advantages of Blood–Brain Barrier to Optimize Delivery of Drugs in Central Neurological Conditions
inferred← citeshttps://doi.org/10.1002/mco2.70712openalex-snapshot
Blood–Brain Barrier: Structure, Function, Diseases, and Drug Delivery Systems
inferred← citeshttps://doi.org/10.1007/s11033-023-08968-3openalex-snapshot
Current non-invasive strategies for brain drug delivery: overcoming blood–brain barrier transport
inferred← citeshttps://doi.org/10.1007/s11060-022-03974-0openalex-snapshot
Focused ultrasound for the treatment of glioblastoma
inferred← citeshttps://doi.org/10.1016/b978-0-323-91865-7.00007-9openalex-snapshot
Blood–brain barrier and nanovesicles for brain-targeting drug delivery
inferred← citeshttps://doi.org/10.1016/b978-0-443-33343-9.00013-2openalex-snapshot
Nanotechnology for overcoming acquired drug resistance in central nervous system cancers
inferred← citeshttps://doi.org/10.1016/j.canlet.2023.216077openalex-snapshot
Exosomes; multifaceted nanoplatform for targeting brain cancers
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2025.06.037openalex-snapshot
Role of Blood-Brain barrier in bacterial translocation
inferred← citeshttps://doi.org/10.70675/886117f7z10f3z4c2dza71az0c108dd39779openalex-snapshot
Intégration de la modélisation pharmacocinétique dans l'étude par imagerie immunoTEP de la réponse du glioblastome à l'immunothérapie combinée aux ultrasons thérapeutiques.
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