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Hypoxia-Inducible Factors as Essential Regulators of Inflammation
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/1521-4141(200102)31:2<480::aid-immu480>3.0.co;2-lopenalex-snapshot
Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation - a potential mechanism
inferredcites →https://doi.org/10.1002/art.11473openalex-snapshot
The transcription factors hypoxia‐inducible factor 1α and Ets‐1 colocalize in the hypoxic synovium of inflamed joints in adjuvant‐induced arthritis
inferredcites →https://doi.org/10.1002/jlb.56.4.423openalex-snapshot
Cytokine networks in solid human tumors: regulation of angiogenesis
inferredcites →https://doi.org/10.1002/jlb.66.6.889openalex-snapshot
Macrophage responses to hypoxia: relevance to disease mechanisms
inferredcites →https://doi.org/10.1002/path.1027openalex-snapshot
The role of tumour‐associated macrophages in tumour progression: implications for new anticancer therapies
inferredcites →https://doi.org/10.1002/path.1029openalex-snapshot
Expression of HIF‐1α by human macrophages: implications for the use of macrophages in hypoxia‐regulated cancer gene therapy
inferredcites →https://doi.org/10.1016/0014-5793(95)00986-jopenalex-snapshot
Hypoxia prolongs neutrophil survival in vitro
inferredcites →https://doi.org/10.1016/0021-9150(89)90101-9openalex-snapshot
Adaptation to arterial wall hypoxia demonstrated in vivo with oxygen microcathodes
inferredcites →https://doi.org/10.1016/j.ccr.2006.12.016openalex-snapshot
Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1016/j.cell.2005.04.014openalex-snapshot
IKKβ Couples Hepatocyte Death to Cytokine-Driven Compensatory Proliferation that Promotes Chemical Hepatocarcinogenesis
inferredcites →https://doi.org/10.1016/j.ejca.2006.01.003openalex-snapshot
Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
inferredcites →https://doi.org/10.1016/j.it.2005.06.007openalex-snapshot
The role of HIF-1α in myeloid cell inflammation
inferredcites →https://doi.org/10.1016/j.jhsa.2007.09.002openalex-snapshot
Synovial Hypoxia as a Cause of Tendon Rupture in Rheumatoid Arthritis
inferredcites →https://doi.org/10.1016/j.molmed.2004.12.007openalex-snapshot
The ‘cytokine profile’: a code for sepsis
inferredcites →https://doi.org/10.1016/s0002-9440(10)64554-3openalex-snapshot
The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages
inferredcites →https://doi.org/10.1016/s0006-291x(03)01073-8openalex-snapshot
Expression of proinflammatory cytokines via HIF-1α and NF-κB activation on desferrioxamine-stimulated HMC-1 cells
inferredcites →https://doi.org/10.1016/s0021-9150(00)00580-3openalex-snapshot
Expression of very low density lipoprotein receptor mRNA in circulating human monocytes: its up-regulation by hypoxia
inferredcites →https://doi.org/10.1016/s0021-9150(03)00302-2openalex-snapshot
Hypoxia increases 25-hydroxycholesterol-induced interleukin-8 protein secretion in human macrophages
inferredcites →https://doi.org/10.1016/s0070-2153(04)62002-3openalex-snapshot
HIFs, Hypoxia, and Vascular Development
inferredcites →https://doi.org/10.1016/s0092-8674(03)00154-5openalex-snapshot
HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation
inferredcites →https://doi.org/10.1016/s0093-7754(01)90210-6openalex-snapshot
Oxygenation status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
inferredcites →https://doi.org/10.1016/s0140-6736(00)04046-0openalex-snapshot
Inflammation and cancer: back to Virchow?
inferredcites →https://doi.org/10.1016/s0888-7543(03)00215-5openalex-snapshot
Genetic amplification of the transcriptional response to hypoxia as a novel means of identifying regulators of angiogenesis
inferredcites →https://doi.org/10.1023/a:1020304003704openalex-snapshot
Tumor-Associated Macrophages in Breast Cancer
inferredcites →https://doi.org/10.1038/330662a0openalex-snapshot
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
inferredcites →https://doi.org/10.1038/bjc.1988.36openalex-snapshot
Macrophages in human breast disease: a quantitative immunohistochemical study
inferredcites →https://doi.org/10.1038/nature06905openalex-snapshot
NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
inferredcites →https://doi.org/10.1038/nrc1256openalex-snapshot
Tumour-educated macrophages promote tumour progression and metastasis
inferredcites →https://doi.org/10.1038/nri2448openalex-snapshot
Exploring the full spectrum of macrophage activation
inferredcites →https://doi.org/10.1038/sj.gt.3301058openalex-snapshot
The macrophage – a novel system to deliver gene therapy to pathological hypoxia
inferredcites →https://doi.org/10.1042/bj20021279openalex-snapshot
Hypoxia-inducible factor induction by tumour necrosis factor in normoxic cells requires receptor-interacting protein-dependent nuclear factor kappaB activation
inferredcites →https://doi.org/10.1042/bj20051839openalex-snapshot
Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-κB
inferredcites →https://doi.org/10.1056/nejm199305203282008openalex-snapshot
Pathogenetic Mechanisms of Septic Shock
inferredcites →https://doi.org/10.1073/pnas.0401339101openalex-snapshot
Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of β 2 integrin gene expression
inferredcites →https://doi.org/10.1074/jbc.m604507200openalex-snapshot
Transforming Growth Factor β1 Induces Hypoxia-inducible Factor-1 Stabilization through Selective Inhibition of PHD2 Expression
inferredcites →https://doi.org/10.1084/jem.177.4.1205openalex-snapshot
Interleukin 10 protects mice from lethal endotoxemia.
inferredcites →https://doi.org/10.1084/jem.183.3.949openalex-snapshot
Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum.
inferredcites →https://doi.org/10.1084/jem.193.6.727openalex-snapshot
Colony-Stimulating Factor 1 Promotes Progression of Mammary Tumors to Malignancy
inferredcites →https://doi.org/10.1084/jem.20040624openalex-snapshot
Hypoxia-induced neutrophil survival is mediated by HIF-1α–dependent NF-κB activity
inferredcites →https://doi.org/10.1089/ars.2007.1825openalex-snapshot
LPS Induces Hypoxia-Inducible Factor 1 Activation in Macrophage-Differentiated Cells in a Reactive Oxygen Species–Dependent Manner
inferredcites →https://doi.org/10.1091/mbc.e02-09-0598openalex-snapshot
Tumor Necrosis Factor-α Causes Accumulation of a Ubiquitinated Form of Hypoxia Inducible Factor-1α through a Nuclear Factor-κB-Dependent Pathway
inferredcites →https://doi.org/10.1093/emboj/20.18.5197openalex-snapshot
Independent function of two destruction domains in hypoxia‐inducible factor‐α chains activated by prolyl hydroxylation
inferredcites →https://doi.org/10.1093/infdis/163.6.1177openalex-snapshot
The Proinflammatory Cytokines Interleukin-l and Tumor Necrosis Factor and Treatment of the Septic Shock Syndrome
inferredcites →https://doi.org/10.1093/jnci/93.4.266openalex-snapshot
Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects
inferredcites →https://doi.org/10.1096/fj.03-0329fjeopenalex-snapshot
IL‐1β mediated up‐regulation of HIF‐lα via an NFkB/COX‐2 pathway identifies HIF‐1 as a critical link between inflammation and oncogenesis
inferredcites →https://doi.org/10.1097/00024382-199711000-00006openalex-snapshot
ANTI-INTERLEUKIN-12 THERAPY PROTECTS MICE IN LETHAL ENDOTOXEMIA BUT IMPAIRS BACTERIAL CLEARANCE IN MURINE ESCHERICHIA COLI PERITONEAL SEPSIS
inferredcites →https://doi.org/10.1101/gad.924501openalex-snapshot
FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
inferredcites →https://doi.org/10.1111/j.1365-2567.2009.03203.xopenalex-snapshot
Hypoxic stress up‐regulates the expression of Toll‐like receptor 4 in macrophages via hypoxia‐inducible factor
inferredcites →https://doi.org/10.1126/science.1059796openalex-snapshot
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
inferredcites →https://doi.org/10.1126/science.1059817openalex-snapshot
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
inferredcites →https://doi.org/10.1126/science.1068592openalex-snapshot
Asparagine Hydroxylation of the HIF Transactivation Domain: A Hypoxic Switch
inferredcites →https://doi.org/10.1126/science.1140485openalex-snapshot
Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
inferredcites →https://doi.org/10.1128/cdli.4.5.607-610.1997openalex-snapshot
Endotoxin-induced lethality in neonatal mice is counteracted by interleukin-10 (IL-10) and exacerbated by anti-IL-10
inferredcites →https://doi.org/10.1128/mcb.22.9.2984-2992.2002openalex-snapshot
Carboxyl-Terminal Transactivation Activity of Hypoxia-Inducible Factor 1α Is Governed by a von Hippel-Lindau Protein-Independent, Hydroxylation-Regulated Association with p300/CBP
inferredcites →https://doi.org/10.1128/mcb.23.24.9361-9374.2003openalex-snapshot
Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene Regulation
inferredcites →https://doi.org/10.1152/ajpcell.00614.2005openalex-snapshot
Activation of hypoxia-inducible factor 1 during macrophage differentiation
inferredcites →https://doi.org/10.1152/physiol.00045.2008openalex-snapshot
Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1
inferredcites →https://doi.org/10.1158/0008-5472.can-05-4005openalex-snapshot
Distinct Role of Macrophages in Different Tumor Microenvironments
inferredcites →https://doi.org/10.1159/000455166openalex-snapshot
Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients
inferredcites →https://doi.org/10.1161/01.atv.17.2.317openalex-snapshot
Macrophages Isolated From Human Atherosclerotic Plaques Produce IL-8, and Oxysterols May Have a Regulatory Function for IL-8 Production
inferredcites →https://doi.org/10.1161/01.atv.19.4.870openalex-snapshot
Evidence of Hypoxic Areas Within the Arterial Wall In Vivo
inferredcites →https://doi.org/10.1164/rccm.200801-008ocopenalex-snapshot
Mast Cells Can Mediate Vascular Permeability through Regulation of the PI3K–HIF-1α–VEGF Axis
inferredcites →https://doi.org/10.1172/jci23865openalex-snapshot
HIF-1α expression regulates the bactericidal capacity of phagocytes
inferredcites →https://doi.org/10.1177/0885066606297123openalex-snapshot
Cellular Mechanisms in Sepsis
inferredcites →https://doi.org/10.1177/108155899804600207openalex-snapshot
Angiogenesis in Rheumatoid Arthritis: Pathogenic and Clinical Significance
inferredcites →https://doi.org/10.1182/blood-2004-03-1109openalex-snapshot
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
inferredcites →https://doi.org/10.1182/blood-2008-12-195941openalex-snapshot
Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
inferredcites →https://doi.org/10.1182/blood.v84.7.2068.bloodjournal8472068openalex-snapshot
Leukocyte-endothelial adhesion molecules
inferredcites →https://doi.org/10.1186/ar2568openalex-snapshot
The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis
inferredcites →https://doi.org/10.1385/ir:21:2-3:129openalex-snapshot
Interleukin-8 and Its Receptor CXCR2 in Atherosclerosis
inferredcites →https://doi.org/10.1586/eri.09.60openalex-snapshot
Host cholesterol and inflammation as common key regulators of toxoplasmosis and artherosclerosis development
inferredcites →https://doi.org/10.2152/jmi.55.78openalex-snapshot
Prognostic significance of HIF-2.ALPHA. expression on tumor infiltrating macrophages in patients with uterine cervical cancer undergoing radiotherapy
inferredcites →https://doi.org/10.3892/ijo.17.3.445openalex-snapshot
Tumor associated macrophages in human prostate cancer: relation to clinicopathological variables and survival.
inferredcites →https://doi.org/10.4049/jimmunol.145.9.2920openalex-snapshot
The role of IFN-gamma in the pathology of experimental endotoxemia.
inferredcites →https://doi.org/10.4049/jimmunol.149.5.1666openalex-snapshot
Evidence for IFN-gamma as a mediator of the lethality of endotoxin and tumor necrosis factor-alpha
inferredcites →https://doi.org/10.4049/jimmunol.155.4.2222openalex-snapshot
Neutralization of IL-10 increases lethality in endotoxemia. Cooperative effects of macrophage inflammatory protein-2 and tumor necrosis factor
inferredcites →https://doi.org/10.4049/jimmunol.175.10.6257openalex-snapshot
Hypoxia Regulates Macrophage Functions in Inflammation
inferredcites →https://doi.org/10.4049/jimmunol.178.12.7516openalex-snapshot
Cutting Edge: Essential Role of Hypoxia Inducible Factor-1α in Development of Lipopolysaccharide-Induced Sepsis
inferredcites →https://doi.org/10.4049/jimmunol.180.7.4697openalex-snapshot
Hypoxia and Hypoxia-Inducible Factor-1α Modulate Lipopolysaccharide-Induced Dendritic Cell Activation and Function
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Combined Intestinal Microbiota and Transcriptomic Analysis to Investigate the Effect of Different Stocking Densities on the Ability of Litopenaeus Vannamei to Utilize Chlorella Sorokiniana
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Inflammation, Hormones, and Metabolism
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Hypoxia downregulates the expression of activating receptors involved in NK ‐cell‐mediated target cell killing without affecting ADCC
inferred← citeshttps://doi.org/10.1002/hep.28468openalex-snapshot
A new HIF‐1α/RANTES‐driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice
inferred← citeshttps://doi.org/10.1002/ijc.29151openalex-snapshot
Micro RNA ‐155 deficiency enhances the recruitment and functions of myeloid‐derived suppressor cells in tumor microenvironment and promotes solid tumor growth
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Conditional Deletion of HIF-2α in Mouse Nucleus Pulposus Reduces Fibrosis and Provides Mild and Transient Protection From Age-Dependent Structural Changes in Intervertebral Disc
inferred← citeshttps://doi.org/10.1002/jcp.24666openalex-snapshot
Short‐Term Hypoxia Enhances the Migratory Capability of Dendritic Cell Through HIF‐1α and PI3K/Akt Pathway
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Revisiting the role of hyperbaric oxygen therapy in knee injuries: Potential benefits and mechanisms
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A disintegrin‐like and metalloproteinase with thrombospondin‐1 (ADAMTS‐1) levels in gingival crevicular fluid correlate with vascular endothelial growth factor‐A, hypoxia‐inducible factor‐1α, and clinical parameters in patients with advanced periodontitis
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Inflammasome Activation Differences Underpin Different Mycobacterium tuberculosis Infection Outcomes
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Redox Regulation of Inflammation: Old Elements, a New Story
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Sparse linear discriminant analysis in structured covariates space
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Hypoxia and Gene Expression
inferred← citeshttps://doi.org/10.1007/978-1-4899-7678-9_12openalex-snapshot
Implications of Oxygen Homeostasis for Tumor Biology and Treatment
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Murine Models of Secondary Cytokine Storm Syndromes
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Hsp60 in Cancer Immunity: Biological Basis, Diagnostic Potential and Therapeutic Opportunities
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Murine Models of Secondary Cytokine Storm Syndromes
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Role of Obesity-Triggered Inflammation in Aging
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Oxygen Treatment for Multiple Sclerosis Patients
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Metabolic Reprogramming and Redox Signaling in Pulmonary Hypertension
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Antiangiogenic Alkaloids from Plants
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Leukocyte-Cancer Cell Fusion: Initiator of the Warburg Effect in Malignancy?
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Prevention of Pro-inflammatory Markers By Medicinal Mushrooms Under Stressful Environment
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Macrophage polarization and its role in the pathogenesis of acute lung injury/acute respiratory distress syndrome
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Syncytin-1 nonfusogenic activities modulate inflammation and contribute to preeclampsia pathogenesis
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Mitochondrial metabolism, reactive oxygen species, and macrophage function-fishing for insights
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Renal hypoxia–HIF–PHD–EPO signaling in transition metal nephrotoxicity: friend or foe?
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The hypoxia-inflammation cycle as a key mechanism of smoldering inflammation and progression in multiple sclerosis
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Oxygen sensing in intestinal mucosal inflammation
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Hypoxia paradoxically inhibits the angiogenic response of isolated vessel explants while inducing overexpression of vascular endothelial growth factor
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The developmental aging and origins of health and disease hypotheses explained by different protein networks
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Identification of HIF-1α promoter and expression regulation of HIF-1α gene by LPS and hypoxia in zebrafish
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Current and novel therapeutic targets in the treatment of rheumatoid arthritis
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Protective properties of the cultured stem cell proteome studied in an animal model of acetaminophen-induced acute liver failure
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Cannabidiol ameliorates lipopolysaccharide-induced cardiovascular toxicity by its antioxidant and anti-inflammatory activity via regulating IL-6, Hif1α, STAT3, eNOS pathway
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Brain Damage in Sleep-Disordered Breathing: The Role of the Glia
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Macrophage polarization and plasticity in health and disease
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The pleiotropic mode and molecular mechanism of macrophages in promoting tumor progression and metastasis
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Comparative Analysis of the Effects of Two Probiotic Bacterial Strains on Metabolism and Innate Immunity in the RAW 264.7 Murine Macrophage Cell Line
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Lactic Acid Bacteria with Probiotic Potential Regulating Macrophages: Mechanisms, Regulatory Features, and Clinical Applications
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Modulation of Macrophage Activation
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Biomaterial-induced microenvironment and host reaction in bone regeneration
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The impact of hypoxia on intestinal invasion by bacterial pathogens
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Impact of MicroRNAs in the Cellular Response to Hypoxia
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Identification of microRNAs involved in the modulation of pro-angiogenic factors in atherosclerosis by a polyphenol-rich extract from propolis
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Manganese oxide particles as cytoprotective, oxygen generating agents
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Role of HIF1α and HIF2α in Cre Recombinase–Induced Retinal Pigment Epithelium Pathology and Its Secondary Effect on Choroidal Neovascularization
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Combined intestinal microbiota and transcriptomic analysis to investigate the effect of different stocking densities on the ability of Pacific white shrimp (Litopenaeus vannamei) to utilize Chlorella sorokiniana
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Hypoxia-inducible factor-1α shifts metabolism from oxidative phosphorylation to glycolysis in response to pathogen challenge in Apostichopus japonicus
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Feed-forward regulation between cellular senescence and immunosuppression promotes the aging process and age-related diseases
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Erythropoietin is a hypoxia inducible factor-induced protective molecule in experimental autoimmune neuritis
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Genome-wide identification of hypoxia-inducible factor-1 and -2 binding sites in hypoxic human macrophages alternatively activated by IL-10
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Palmitic acid induces nDNA release to cytosol and promotes microglial M1 polarization via cGAS-STING signaling pathway
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Oligodendrocytes modulate the immune-inflammatory response in EAE via TNFR2 signaling
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Corrigendum to: Oligodendrocytes modulate the immune-inflammatory response in EAE via TNFR2 signaling
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Hypoxia stimulates microenvironment in human embryonic stem cell through inflammatory signalling: An integrative analysis
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Evaluation of hypoxia inducible factor expression in inflammatory and neurodegenerative brain models
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Anti-inflammatory mechanism of various metal and metal oxide nanoparticles synthesized using plant extracts: A review
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Effects of hypoxic exposure on immune responses of intestinal mucosa to Citrobacter colitis in mice
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2020.12.003openalex-snapshot
Naringenin improves depressive- and anxiety-like behaviors in mice exposed to repeated hypoxic stress through modulation of oxido-inflammatory mediators and NF-kB/BDNF expressions
inferred← citeshttps://doi.org/10.1016/j.canlet.2013.08.014openalex-snapshot
Molecular mechanisms underlying chronic inflammation-associated cancers
inferred← citeshttps://doi.org/10.1016/j.canlet.2019.03.015openalex-snapshot
Metabolic reprogramming of macrophages during infections and cancer
inferred← citeshttps://doi.org/10.1016/j.cellsig.2013.06.007openalex-snapshot
Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.02.098openalex-snapshot
The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis
inferred← citeshttps://doi.org/10.1016/j.cmet.2011.11.013openalex-snapshot
Orchestration of Metabolism by Macrophages
inferred← citeshttps://doi.org/10.1016/j.cmet.2017.06.018openalex-snapshot
Inflammasomes on the Crossroads of Innate Immune Recognition and Metabolic Control
inferred← citeshttps://doi.org/10.1016/j.colsurfa.2022.129294openalex-snapshot
Functional silver nanozymes regulate cell inflammatory cytokines expression in mouse macrophages
inferred← citeshttps://doi.org/10.1016/j.csbj.2022.06.034openalex-snapshot
A multi-omics deep learning model for hypoxia phenotype to predict tumor aggressiveness and prognosis in uveal melanoma for rationalized hypoxia-targeted therapy
inferred← citeshttps://doi.org/10.1016/j.cyto.2013.05.028openalex-snapshot
TNF-alpha promoter methylation in peripheral white blood cells: Relationship with circulating TNFα, truncal fat and n-6 PUFA intake in young women
inferred← citeshttps://doi.org/10.1016/j.devcel.2020.07.015openalex-snapshot
Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production
inferred← citeshttps://doi.org/10.1016/j.ejphar.2019.04.032openalex-snapshot
Proteomic analysis of flavokawain C-induced cell death in HCT 116 colon carcinoma cell line
inferred← citeshttps://doi.org/10.1016/j.envint.2020.106212openalex-snapshot
Low dose ionizing radiation effects on the immune system
inferred← citeshttps://doi.org/10.1016/j.envres.2023.116045openalex-snapshot
Biogenic silver based nanostructures: Synthesis, mechanistic approach and biological applications
inferred← citeshttps://doi.org/10.1016/j.febslet.2012.04.032openalex-snapshot
Systemic VHL gene functions and the VHL disease
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2011.08.034openalex-snapshot
Oxygen-dependent regulation of nitric oxide production by inducible nitric oxide synthase
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2021.01.010openalex-snapshot
Nitric oxide and hydrogen sulfide: Sibling rivalry in the family of epigenetic regulators
inferred← citeshttps://doi.org/10.1016/j.fsi.2023.109222openalex-snapshot
Role of HIF in fish inflammation
inferred← citeshttps://doi.org/10.1016/j.fsi.2026.111539openalex-snapshot
iTRAQ-based proteomic identification of cyclophilin as a candidate mediator for cyclosporin A-mediated immunomodulation in pearl oysters Pinctada fucata martensii
inferred← citeshttps://doi.org/10.1016/j.healun.2015.12.021openalex-snapshot
Increased myeloid cell hypoxia-inducible factor-1 delays obliterative airway disease in the mouse
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2017.04.114openalex-snapshot
Effect of chitosan and coagulation factors on the wound repair phenotype of bioengineered blood clots
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.145830openalex-snapshot
Fucosylated chondroitin sulfate exerts in vitro anti-tumor property through manipulating the metabolism related polarization of macrophages
inferred← citeshttps://doi.org/10.1016/j.ijporl.2011.02.001openalex-snapshot
Microarray analysis of microRNA expression in LPS induced inflammation of human middle ear epithelial cells (HMEECs)
inferred← citeshttps://doi.org/10.1016/j.imbio.2012.07.023openalex-snapshot
Dendritic cell reprogramming by the hypoxic environment
inferred← citeshttps://doi.org/10.1016/j.immuni.2013.04.005openalex-snapshot
Metabolic Pathways in Immune Cell Activation and Quiescence
inferred← citeshttps://doi.org/10.1016/j.immuni.2021.12.013openalex-snapshot
Inflammation in obesity, diabetes, and related disorders
inferred← citeshttps://doi.org/10.1016/j.intimp.2016.09.010openalex-snapshot
Protective effects of puerarin on acute lung and cerebrum injury induced by hypobaric hypoxia via the regulation of aquaporin (AQP) via NF-κB signaling pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110470openalex-snapshot
Hypoxia effects on oncolytic virotherapy in Cancer: Friend or Foe?
inferred← citeshttps://doi.org/10.1016/j.isci.2019.08.033openalex-snapshot
Controlling the Phenotype of Tumor-Infiltrating Macrophages via the PHD-HIF Axis Inhibits Tumor Growth in a Mouse Model
inferred← citeshttps://doi.org/10.1016/j.it.2011.12.001openalex-snapshot
Differential macrophage programming in the tumor microenvironment
inferred← citeshttps://doi.org/10.1016/j.jare.2023.11.020openalex-snapshot
CORM‑2 reduces cisplatin accumulation in the mouse inner ear and protects against cisplatin-induced ototoxicity
inferred← citeshttps://doi.org/10.1016/j.jconrel.2022.01.029openalex-snapshot
CaP-based anti-inflammatory HIF-1α siRNA-encapsulating nanoparticle for rheumatoid arthritis therapy
inferred← citeshttps://doi.org/10.1016/j.jcpa.2016.06.006openalex-snapshot
Prevalence of FoxP3 + Cells in Canine Tumours and Lymph Nodes Correlates Positively with Glucose Transporter 1 Expression
inferred← citeshttps://doi.org/10.1016/j.jhep.2014.08.025openalex-snapshot
Hypoxia inducible factors in liver disease and hepatocellular carcinoma: Current understanding and future directions
inferred← citeshttps://doi.org/10.1016/j.joen.2013.10.029openalex-snapshot
Cellular and Molecular Tissue Response to Triple Antibiotic Intracanal Dressing
inferred← citeshttps://doi.org/10.1016/j.joen.2015.05.008openalex-snapshot
Sirtuin 6 Modulates Hypoxia-induced Apoptosis in Osteoblasts via Inhibition of Glycolysis: Implication for Pathogenesis of Periapical Lesions
inferred← citeshttps://doi.org/10.1016/j.jpedsurg.2018.01.023openalex-snapshot
Deferoxamine preconditioning activated hypoxia-inducible factor-1α and MyD88-dependent Toll-like receptor 4 signaling in intestinal stem cells
inferred← citeshttps://doi.org/10.1016/j.jtha.2024.02.018openalex-snapshot
Redox regulation of platelet function and thrombosis
inferred← citeshttps://doi.org/10.1016/j.lfs.2013.04.001openalex-snapshot
Neovascularization in diabetes and its complications. Unraveling the angiogenic paradox
inferred← citeshttps://doi.org/10.1016/j.lfs.2020.117423openalex-snapshot
Nicorandil ameliorates bleomycin-induced pulmonary fibrosis in rats through modulating eNOS, iNOS, TXNIP and HIF-1α levels
inferred← citeshttps://doi.org/10.1016/j.mce.2014.04.009openalex-snapshot
Expression and regulation of stromal cell-derived factor-1 (SDF1) and chemokine CXC motif receptor 4 (CXCR4) in equine and bovine preovulatory follicles
inferred← citeshttps://doi.org/10.1016/j.mehy.2020.109664openalex-snapshot
Controlled hypobaric hypoxia increases immunological tolerance by modifying HLA-G expression, a potential therapy to inflammatory diseases
inferred← citeshttps://doi.org/10.1016/j.mito.2020.10.003openalex-snapshot
The contribution of uncoupling protein 2 to mitochondrial Ca2+ homeostasis in health and disease – A short revisit
inferred← citeshttps://doi.org/10.1016/j.molonc.2016.08.002openalex-snapshot
Biglycan stimulates VEGF expression in endothelial cells by activating the TLR signaling pathway
inferred← citeshttps://doi.org/10.1016/j.neuint.2020.104919openalex-snapshot
Hypoperfusion is a potential inducer of immunosuppressive network in Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.neuint.2024.105747openalex-snapshot
The Janus face of HIF-1α in ischemic stroke and the possible associated pathways
inferred← citeshttps://doi.org/10.1016/j.obmed.2022.100432openalex-snapshot
Healthy dietary choices are associated with higher serum propionate and PGC1α expression in peripheral blood mononuclear cells in adult humans
inferred← citeshttps://doi.org/10.1016/j.omtn.2020.04.002openalex-snapshot
The Interplay among miRNAs, Major Cytokines, and Cancer-Related Inflammation
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2023.09.002openalex-snapshot
HIF-1α and periodontitis: Novel insights linking host-environment interplay to periodontal phenotypes
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2021.107986openalex-snapshot
Modulating tumor-associated macrophages to enhance the efficacy of immune checkpoint inhibitors: A TAM-pting approach
inferred← citeshttps://doi.org/10.1016/j.phrs.2024.107170openalex-snapshot
SARS-CoV-2 mitochondrial metabolic and epigenomic reprogramming in COVID-19
inferred← citeshttps://doi.org/10.1016/j.phymed.2019.152976openalex-snapshot
Sedum sarmentosum Bunge extract alleviates inflammation and kidney injury via inhibition of M1-macrophage polarization
inferred← citeshttps://doi.org/10.1016/j.pnpbp.2020.109858openalex-snapshot
The role of microglia in neuroprogressive disorders: mechanisms and possible neurotherapeutic effects of induced ketosis
inferred← citeshttps://doi.org/10.1016/j.prosdent.2021.09.003openalex-snapshot
Ion release and biocompatibility of Co-Cr alloy fabricated by selective laser melting from recycled Co-Cr powder: An in vitro study
inferred← citeshttps://doi.org/10.1016/j.prp.2019.01.022openalex-snapshot
Roles of HIF1α- and HIF2α-regulated BNIP3 in hypoxia-induced injury of neurons
inferred← citeshttps://doi.org/10.1016/j.redox.2023.102753openalex-snapshot
Vitamin C: From nutrition to oxygen sensing and epigenetics
inferred← citeshttps://doi.org/10.1016/j.redox.2026.104220openalex-snapshot
HIF inhibition: Current strategies and clinical challenges
inferred← citeshttps://doi.org/10.1016/j.resp.2013.02.017openalex-snapshot
Inflammatory and immunomodulatory mechanisms in the carotid body
inferred← citeshttps://doi.org/10.1016/j.smrv.2011.09.003openalex-snapshot
Restless legs syndrome – Theoretical roles of inflammatory and immune mechanisms
inferred← citeshttps://doi.org/10.1016/j.smrv.2015.05.006openalex-snapshot
Obstructive sleep apnea and cancer: Epidemiologic links and theoretical biological constructs
inferred← citeshttps://doi.org/10.1016/j.tem.2017.11.008openalex-snapshot
The Metabolic Microenvironment Steers Bone Tissue Regeneration
inferred← citeshttps://doi.org/10.1016/j.toxcx.2024.100198openalex-snapshot
Cytokines and their regulators in rat lung following scorpion envenomation
inferred← citeshttps://doi.org/10.1016/j.trsl.2017.02.002openalex-snapshot
Vascular precursor cells in tissue injury repair
inferred← citeshttps://doi.org/10.1016/j.trsl.2023.09.006openalex-snapshot
Dysfunctional Cori and Krebs cycle and inhibition of lactate transporters constitute a mechanism of primary nonfunction of fatty liver allografts
inferred← citeshttps://doi.org/10.1016/j.wneu.2020.05.256openalex-snapshot
Expression Patterns of Hypoxia-Inducible Factors, Proinflammatory, and Neuroprotective Cytokines in Neuroepithelial Tissues of Lumbar Spinal Lipomas–A Pilot Study
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2010.09.023openalex-snapshot
Mitochondrial complex II participates in normoxic and hypoxic regulation of α-keto acids in the murine heart
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2013.12.021openalex-snapshot
Systemic toll-like receptor and interleukin-18 pathway activation in patients with acute ST elevation myocardial infarction
inferred← citeshttps://doi.org/10.1017/neu.2022.21openalex-snapshot
Lowered oxygen saturation and increased body temperature in acute COVID-19 largely predict chronic fatigue syndrome and affective symptoms due to Long COVID: A precision nomothetic approach
inferred← citeshttps://doi.org/10.1021/acsabm.9b00775openalex-snapshot
Oxygen-Sensing Probes and Bandage for Optical Detection of Inflammation
inferred← citeshttps://doi.org/10.1021/acsami.4c08154openalex-snapshot
Immunomodulatory Behavior of Tendon Magnetic Cell Sheets can be Modulated in Hypoxic Environments under Magnetic Stimulus
inferred← citeshttps://doi.org/10.1021/acsestair.6c00100openalex-snapshot
Early-Life PM1 Exposure Triggers Olfactory-Associated Neuroinflammation and Disrupts Brain Development
inferred← citeshttps://doi.org/10.1038/bjc.2016.105openalex-snapshot
Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level
inferred← citeshttps://doi.org/10.1038/icb.2016.107openalex-snapshot
Hypoxic modulation of hepatocyte responses to the cytokine interleukin‐22
inferred← citeshttps://doi.org/10.1038/ncomms12177openalex-snapshot
Phagocyte respiratory burst activates macrophage erythropoietin signalling to promote acute inflammation resolution
inferred← citeshttps://doi.org/10.1038/ncomms14268openalex-snapshot
Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection
inferred← citeshttps://doi.org/10.1038/ncomms2677openalex-snapshot
FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4
inferred← citeshttps://doi.org/10.1038/ni.2109openalex-snapshot
Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils
inferred← citeshttps://doi.org/10.1038/s12276-022-00739-7openalex-snapshot
Sirtuins are crucial regulators of T cell metabolism and functions
inferred← citeshttps://doi.org/10.1038/s41417-021-00354-0openalex-snapshot
Inhibition of host Ogr1 enhances effector CD8+ T-cell function by modulating acidic microenvironment
inferred← citeshttps://doi.org/10.1038/s41598-019-57386-8openalex-snapshot
A Boolean Model of Microvascular Rarefaction to Predict Treatment Outcomes in Renal Disease
inferred← citeshttps://doi.org/10.1038/s41598-022-05658-1openalex-snapshot
Chronic inflammation markers and cytokine-specific autoantibodies in Danish blood donors with restless legs syndrome
inferred← citeshttps://doi.org/10.1038/s41598-023-41686-1openalex-snapshot
Expression of hypoxia-inducible genes is suppressed in altered gravity due to impaired nuclear HIF1α accumulation
inferred← citeshttps://doi.org/10.1038/s42003-024-05764-yopenalex-snapshot
Novel lncRNA regulatory elements in milk somatic cells of Holstein dairy cows associated with mastitis
inferred← citeshttps://doi.org/10.1038/srep18176openalex-snapshot
Infection with Mycobacterium tuberculosis induces the Warburg effect in mouse lungs
inferred← citeshttps://doi.org/10.1038/srep25881openalex-snapshot
Impact of maternal cigarette smoke exposure on brain inflammation and oxidative stress in male mice offspring
inferred← citeshttps://doi.org/10.1074/jbc.m117.805655openalex-snapshot
Hypoxia-inducible factor 2α (HIF-2α) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity
inferred← citeshttps://doi.org/10.1080/07853890.2020.1858234openalex-snapshot
Increased expression of hypoxia-induced factor 1α mRNA and its related genes in myeloid blood cells from critically ill COVID-19 patients
inferred← citeshttps://doi.org/10.1080/14767058.2018.1432037openalex-snapshot
Amniotic fluid HIF1α and exosomal HIF1α in cervical insufficiency patients with physical examination-indicated cerclage
inferred← citeshttps://doi.org/10.1080/17460441.2019.1567488openalex-snapshot
Novel approaches for designing drugs that interfere with pH regulation
inferred← citeshttps://doi.org/10.1088/2516-1091/ae16f1openalex-snapshot
Cutting-edge approaches to diagnosing and treating limb ischemia in peripheral arterial disease
inferred← citeshttps://doi.org/10.1089/ars.2017.7217openalex-snapshot
Hallmarks of Pulmonary Hypertension: Mesenchymal and Inflammatory Cell Metabolic Reprogramming
inferred← citeshttps://doi.org/10.1089/ten.tec.2016.0037openalex-snapshot
3D Human Adipose-Derived Stem Cell Clusters as a Model for In Vitro Fibrosis
inferred← citeshttps://doi.org/10.1089/vim.2022.0112openalex-snapshot
New Avenues to Explore in SARS-CoV-2 Infection: Both TRIM25 and TRIM56 Positively Correlate with VEGF, GAS6, and sAXL in COVID-19 Patients
inferred← citeshttps://doi.org/10.1093/burnst/tkag044openalex-snapshot
Reversing diabetic wound stagnation: macrophage polarization dysregulation as a therapeutic linchpin from pathogenesis to precision interventions
inferred← citeshttps://doi.org/10.1093/cvr/cvab152openalex-snapshot
Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling
inferred← citeshttps://doi.org/10.1093/cvr/cvab284openalex-snapshot
Cardiovascular comorbidities, inflammation, and cerebral small vessel disease
inferred← citeshttps://doi.org/10.1097/fjc.0000000000001201openalex-snapshot
Can Epigenetics Help Solve the Puzzle Between Concomitant Cardiovascular Injury and Severity of Coronavirus Disease 2019?
inferred← citeshttps://doi.org/10.1097/shk.0000000000000212openalex-snapshot
Critical Role of Toll-Like Receptor 4 in Hypoxia-Inducible Factor 1α Activation During Trauma/Hemorrhagic Shock–Induced Acute Lung Injury After Lymph Infusion in Mice
inferred← citeshttps://doi.org/10.1097/shk.0000000000001694openalex-snapshot
HIF-1α and Hypoxia Responsive Genes are Differentially Expressed in Leukocytes From Survivors and Non-Survivors Patients During Clinical Sepsis
inferred← citeshttps://doi.org/10.1097/sla.0b013e318295c160openalex-snapshot
Hypoxia After Liver Surgery Imposes an Aggressive Cancer Stem Cell Phenotype on Residual Tumor Cells
inferred← citeshttps://doi.org/10.1101/2022.04.10.22273660openalex-snapshot
Lowered oxygen saturation and increased body temperature in acute COVID-19 largely predict chronic fatigue syndrome and affective symptoms due to LONG COVID: a precision nomothetic approach
inferred← citeshttps://doi.org/10.1101/2022.07.26.501613openalex-snapshot
Biofilm competency of Desulfovibrio vulgaris Hildenborough facilitates colonization in the gut and represses adenoma development in a rat model of colon cancer
inferred← citeshttps://doi.org/10.1101/536862openalex-snapshot
Hif-1α stabilisation polarises macrophages via cyclooxygenase/prostaglandin E2 in vivo
inferred← citeshttps://doi.org/10.1101/748566openalex-snapshot
Bidirectional crosstalk between Hypoxia-Inducible Factor and glucocorticoid signalling in zebrafish larvae
inferred← citeshttps://doi.org/10.1109/dsaa.2016.66openalex-snapshot
Sparse Linear Discriminant Analysis in Structured Covariates Space
inferred← citeshttps://doi.org/10.1111/aji.12417openalex-snapshot
Placental Regulation of Inflammation and Hypoxia after TNF ‐α Infusion in Mice
inferred← citeshttps://doi.org/10.1111/apha.13472openalex-snapshot
Finally, a promising model for high‐altitude pulmonary edema (HAPE)—A Mountaineers’ Malady
inferred← citeshttps://doi.org/10.1111/bcpt.14081openalex-snapshot
Effects of hypothermia and hypoxia on cytochrome P450‐mediated drug metabolism in neonatal Göttingen minipigs
inferred← citeshttps://doi.org/10.1111/cns.14858openalex-snapshot
The neuroprotective effects of normobaric oxygen therapy after stroke
inferred← citeshttps://doi.org/10.1111/iej.12742openalex-snapshot
Sirtuin 6 attenuates periapical lesion propagation by modulating hypoxia‐induced chemokine (C‐C motif) ligand 2 production in osteoblasts
inferred← citeshttps://doi.org/10.1111/iej.13055openalex-snapshot
Simvastatin alleviates bone resorption in apical periodontitis possibly by inhibition of mitophagy‐related osteoblast apoptosis
inferred← citeshttps://doi.org/10.1111/jre.12239openalex-snapshot
Assessment of the hemodynamic profile in periodontal tissues of diabetic subjects with periodontitis by optical spectroscopy
inferred← citeshttps://doi.org/10.1128/iai.00124-21openalex-snapshot
Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
inferred← citeshttps://doi.org/10.1128/iai.00302-13openalex-snapshot
Hypoxia-Inducible Factor 1-Regulated Lysyl Oxidase Is Involved in Staphylococcus aureus Abscess Formation
inferred← citeshttps://doi.org/10.1128/iai.01003-12openalex-snapshot
Activation of the Nlrp1b Inflammasome by Reduction of Cytosolic ATP
inferred← citeshttps://doi.org/10.1134/s0006297922090140openalex-snapshot
Segregation of α- and β-Globin Gene Cluster in Vertebrate Evolution: Chance or Necessity?
inferred← citeshttps://doi.org/10.1134/s2079086418060075openalex-snapshot
HIF-1 as a Marker of Age-Related Diseases Associated with Tissue Hypoxia
inferred← citeshttps://doi.org/10.1136/jclinpath-2012-200828openalex-snapshot
The role of hypoxia-inducible factor 1 in atherosclerosis: Figure 1
inferred← citeshttps://doi.org/10.1136/jitc-2020-001341openalex-snapshot
Tumor-associated macrophages: potential therapeutic strategies and future prospects in cancer
inferred← citeshttps://doi.org/10.1146/annurev-physiol-021115-105202openalex-snapshot
Role of Intestinal HIF-2α in Health and Disease
inferred← citeshttps://doi.org/10.1152/ajpregu.00657.2010openalex-snapshot
Renovascular disease, microcirculation, and the progression of renal injury: role of angiogenesis
inferred← citeshttps://doi.org/10.1152/ajprenal.00673.2013openalex-snapshot
Silencing of hypoxia-inducible factor-1α gene attenuates chronic ischemic renal injury in two-kidney, one-clip rats
inferred← citeshttps://doi.org/10.1155/2015/687386openalex-snapshot
Zeaxanthin Inhibits Hypoxia-Induced VEGF Secretion by RPE Cells through Decreased Protein Levels of Hypoxia-Inducible Factors-1α
inferred← citeshttps://doi.org/10.1155/2015/791060openalex-snapshot
Cancer as a Proinflammatory Environment: Metastasis and Cachexia
inferred← citeshttps://doi.org/10.1155/2018/5906819openalex-snapshot
Transcriptional Profiling Suggests Extensive Metabolic Rewiring of Human and Mouse Macrophages during Early Interferon Alpha Responses
inferred← citeshttps://doi.org/10.11606/t.5.2023.tde-03042024-150206openalex-snapshot
Efeito da oxigenoterapia hiperbárica na reconstrução do ligamento cruzado anterior em modelo experimental em coelhos
inferred← citeshttps://doi.org/10.11606/t.58.2012.tde-22052012-134952openalex-snapshot
Resposta celular e molecular do tecido conjuntivo de camundongos e medicações intracanal
inferred← citeshttps://doi.org/10.1161/circresaha.117.311400openalex-snapshot
Mitochondrial Oxidative Stress Reduces the Immunopotency of Mesenchymal Stromal Cells in Adults With Coronary Artery Disease
inferred← citeshttps://doi.org/10.11622/smedj.2016154openalex-snapshot
Association between the neutrophil-to-lymphocyte ratio, a new marker of systemic inflammation, and restless legs syndrome
inferred← citeshttps://doi.org/10.1165/rcmb.2016-0186ocopenalex-snapshot
Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis
inferred← citeshttps://doi.org/10.1167/iovs.61.12.24openalex-snapshot
Fursultiamine Alleviates Choroidal Neovascularization by Suppressing Inflammation and Metabolic Reprogramming
inferred← citeshttps://doi.org/10.1172/jci84426openalex-snapshot
Hypoxia-inducible factors: key regulators of myeloid cells during inflammation
inferred← citeshttps://doi.org/10.1182/bloodadvances.2018015669openalex-snapshot
TLR-activated repression of Fe-S cluster biogenesis drives a metabolic shift and alters histone and tubulin acetylation
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