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Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Considerations for the pre-clinical evaluation of new psychiatric drugs: A case study with phenothiazine-like tranquilizers
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The effects of meprobamate, barbiturates, d-amphetamine and promazine on experimentally induced conflict in the rat
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Drug Screening and Evaluative Procedures
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System Analysis: A Strategy for Drug Experimentation and Evaluation
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An Introduction to the Study of Experimental Medicine
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Primary Observation (Irwin) Test in Rodents for Assessing Acute Toxicity of a Test Agent and its Effects on Behavior and Physiological Function
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Evaluation of Neurotoxicity Potential in Rats: The Functional Observational Battery
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Overview of Mouse Assays of Ethanol Intoxication
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Nonclinical Safety Pharmacology Studies Recommended for Support of First‐in‐Human Clinical Trials
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The Planning, Conduct, and Interpretation of Safety Pharmacology Studies: The Role of the Study Director in Safety Pharmacology Investigations
inferred← citeshttps://doi.org/10.1002/9781119053248.ch15openalex-snapshot
Predicting Organ ToxicityIn Vivo—Central Nervous System
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Specific Considerations for Preclinical Development of Inhaled Oligonucleotides
inferred← citeshttps://doi.org/10.1002/9781119555278.ch5openalex-snapshot
Phenotyping of genetically modified mice
inferred← citeshttps://doi.org/10.1002/9781119769484.ch23openalex-snapshot
Nonclinical Characterization and Documentation for Marketing Authorizations of Herbal Formulations
inferred← citeshttps://doi.org/10.1002/9781444318777.ch5openalex-snapshot
Phenotyping of Genetically Modified Mice
inferred← citeshttps://doi.org/10.1002/9783527611942.ch3openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/9783527679348.ch05openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/9783527801756.ch19openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ardp.19783110104openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ardp.19793120707openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ardp.19793121203openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ardp.19803130306openalex-snapshot
Neuropsychotrope Aktivität dopaminanaloger Phenylpropyl‐ und Phenylcyclopropylpiperidine
inferred← citeshttps://doi.org/10.1002/ardp.19853180902openalex-snapshot
Lactone, 6. Mitt. H1‐Histaminolytische, neurotrop spasmolytische und zentral sedierende α‐Aminomethyl‐γ,γ‐diaryl‐γ‐lactone
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Neuropsychotrope aktivität dopaminanaloger bicyclo[2.2.1]‐heptane
inferred← citeshttps://doi.org/10.1002/ardp.19883210905openalex-snapshot
Azaindol‐Derivate II: Synthese und analgetische Wirkung von Pyrazolo[1,5‐a]pyridinen
inferred← citeshttps://doi.org/10.1002/ardp.19923250206openalex-snapshot
Synthesis and Preliminary Pharmacological Study of Thiophene Analogues of the Antipyretic and Analgesic Agent Ethenzamide
inferred← citeshttps://doi.org/10.1002/ardp.19923251007openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ardp.19923251110openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ardp.19933260208openalex-snapshot
Stereoselektive Synthese neuer zentral wirksamer Tricyclen vom Benzomorphan‐Typ mit 2‐Phenylethylamin Partialstruktur
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inferred← citeshttps://doi.org/10.1002/ardp.19933260904openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ardp.19933261011openalex-snapshot
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NSAI Activity Study of 4‐Phenyl‐2‐thioxo‐benzo[4,5]thieno [2,3‐d]pyrimidine Derivatives
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Some Analogues of 1,4‐Disubstituted Piperazines as Hypnotic and Sedative Agents
inferred← citeshttps://doi.org/10.1002/ardp.19953280604openalex-snapshot
Tricyclic CNS Active Agents by Intramolecular Oxa‐Pictet‐Spengler Reaction
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Synthesis and Anti‐inflammatory Evaluation of New Sulfamoylheterocarboxylic Derivatives
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Synthesis and Antidepressant Evaluation of New Hetero[2,1]benzothiazepine Derivatives
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Synthese und zentrale Wirkungen von 4‐hydroxy‐(alkyl)‐ und 4‐amino‐(alkyl)‐substituierten 2,6‐Epoxy‐3‐benzoxocinen
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inferred← citeshttps://doi.org/10.1002/bdr2.2284openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/bdr2.2291openalex-snapshot
Evaluation of gadolinium‐based contrast agents in pregnant CD ‐1 mice and subsequent in utero exposure of the developing offspring, including behavioral evaluations
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Evaluation of Gadolinium‐Based Contrast Agents in Juvenile Non‐Human Primates Including Behavioral Evaluations Such as Learning and Memory
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inferred← citeshttps://doi.org/10.1002/bdrb.21000openalex-snapshot
Multigeneration Reproductive Study of Hydroxyprogesterone Caproate ( HPC ) in the Rat: Laboratory Results and Clinical Significance
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Axotomy‐induced target disconnection promotes an additional death mechanism involved in motoneuron degeneration in amyotrophic lateral sclerosis transgenic mice
inferred← citeshttps://doi.org/10.1002/cne.23814openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ddr.10330openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ddr.20145openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ddr.21002openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ddr.430250204openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ddr.430250404openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ddr.430270407openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/ddr.430350406openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/epi4.12721openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/hipo.20229openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/hup.2560openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/jat.4663openalex-snapshot
90‐day oral toxicity study in rats of a protein‐rich powder derived from Xanthobacter sp. SoF1
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inferred← citeshttps://doi.org/10.1002/jhet.5570270340openalex-snapshot
Synthesis of cns potentially active bicyclic and tricyclic derivatives of pyrazolo[1,5‐a][1,3]diazepines
inferred← citeshttps://doi.org/10.1002/jlac.1992199201204openalex-snapshot
[3 + 5]‐Anellierung mit Homophthalaldehyd: Schlüsselreaktion zur Gewinnung zentral wirksamer Tricyclen
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inferred← citeshttps://doi.org/10.1002/jlac.1995199507173openalex-snapshot
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Dantrolene, a Direct Acting Skeletal Muscle Relaxant
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inferred← citeshttps://doi.org/10.1002/jps.2600621229openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/jps.2600630606openalex-snapshot
Synthesis and CNS Activity of 3-Substituted 7-Chloro-5-Phenyl-1,3,4-Benzotriazepin-2-ones
inferred← citeshttps://doi.org/10.1002/jps.2600640234openalex-snapshot
5‐Chloro‐2‐Pyrimidinyl Analog of Dantrolene
inferred← citeshttps://doi.org/10.1002/jps.2600640641openalex-snapshot
Positional Isomer of the Muscle Relaxant Dantrolene
inferred← citeshttps://doi.org/10.1002/jps.2600670927openalex-snapshot
New Drug Metabolism Inhibitor of Marine Origin
inferred← citeshttps://doi.org/10.1002/jps.2600680319openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/jps.2600690319openalex-snapshot
Synthesis and Skeletal Muscle Relaxant Activity of Quaternary Ammonium Salts of Dantrolene and Clodanolene
inferred← citeshttps://doi.org/10.1002/jps.2600691020openalex-snapshot
1-(substituted benzyl)-3,4,5,6-tetrahydro-2(1H)-pyrimidones: A series with stimulant and depressant activities
inferred← citeshttps://doi.org/10.1002/jps.2600691022openalex-snapshot
Isolation, synthesis, and pharmacology of metabolites of 1-(3,4-dichlorobenzyl)-3,4,5,6-tetrahydro-2(1H)-pyrimidone
inferred← citeshttps://doi.org/10.1002/jps.2600691128openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/jps.2600700933openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/jps.2600781012openalex-snapshot
Improved Anticonvulsant Activity of Phenytoin by a Redox Brain Delivery System III: Brain Uptake and Pharmacological Effects
inferred← citeshttps://doi.org/10.1002/mrm.22411openalex-snapshot
Contrast‐enhanced in vivo magnetic resonance microscopy of the mouse brain enabled by noninvasive opening of the blood‐brain barrier with ultrasound
inferred← citeshttps://doi.org/10.1002/neu.10173openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/neu.480120209openalex-snapshot
Alteration of fucose/leucine incorporation into PNS myelin by isoniazid neuropathy
inferred← citeshttps://doi.org/10.1002/pauz.19960250509openalex-snapshot
Benzomorphananaloge Tricyclen: Synthese und Pharmakologische Eigenschaften
inferred← citeshttps://doi.org/10.1002/pst.527openalex-snapshot
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Neuropharmacological activity of Prunus spinosa stem extract in mice
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Ellagitannins and triterpenoids extracts of Anogeissus leiocarpus stem bark extracts: Protective effects against osteoarthritis
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A high‐dimensional joint model for longitudinal outcomes of different nature
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Selective Hypoxia‐Cytotoxin 7‐Fluoro‐2‐Aminophenazine 5,10‐Dioxide: Toward “Candidate‐to‐Drug” Stage in the Drug‐Development Pipeline
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Antihyperglycemic Effects of Boswellia papyrifera Oleo‐Gum Resin Against Alloxan‐Induced Diabetic Rats
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Two‐phase teratology study with the synthetic prostaglandin ONO‐802 given intravaginally to rats
inferred← citeshttps://doi.org/10.1002/tera.1420200106openalex-snapshot
Development and standardization of screening methods for behavioral teratology
inferred← citeshttps://doi.org/10.1006/exnr.2000.7504openalex-snapshot
A Functional Role for Complex Gangliosides: Motor Deficits in GM2/GD2 Synthase Knockout Mice
inferred← citeshttps://doi.org/10.1006/hbeh.1997.1382openalex-snapshot
A Proposed Test Battery and Constellations of Specific Behavioral Paradigms to Investigate the Behavioral Phenotypes of Transgenic and Knockout Mice
inferred← citeshttps://doi.org/10.1006/rtph.1998.1228openalex-snapshot
Expanded Clinical Observations in Toxicity Studies: Historical Perspectives and Contemporary Issues
inferred← citeshttps://doi.org/10.1007/0-387-32824-6_8openalex-snapshot
In Vivo Effects of a Potent, Selective Dppii Inhibitor
inferred← citeshttps://doi.org/10.1007/3-540-29804-5_3openalex-snapshot
Central Nervous System (CNS) Safety Pharmacology Studies
inferred← citeshttps://doi.org/10.1007/3-540-29837-1_6openalex-snapshot
Psychotropic and neurotropic activity1
inferred← citeshttps://doi.org/10.1007/978-1-0716-1637-6_8openalex-snapshot
The Functional Observation Battery: Utility in Safety Assessment of New Molecular Entities
inferred← citeshttps://doi.org/10.1007/978-1-349-10705-6_2openalex-snapshot
The Pharmacological Background
inferred← citeshttps://doi.org/10.1007/978-1-349-12667-5_5openalex-snapshot
Alternative Methods and Their Application in Neurotoxicity Testing
inferred← citeshttps://doi.org/10.1007/978-1-4613-0735-8_7openalex-snapshot
Testing Animal Behavioral Teratogens
inferred← citeshttps://doi.org/10.1007/978-1-4614-5950-7_11openalex-snapshot
Safety Pharmacology: Guidelines S7A and S7B
inferred← citeshttps://doi.org/10.1007/978-1-4684-2184-2_13openalex-snapshot
Drug Effects on Foot-Shock-Induced Agitation in Mice
inferred← citeshttps://doi.org/10.1007/978-1-4757-4860-4_5openalex-snapshot
Promises and Limitations of Transgenic and Knockout Mice in Modeling Psychiatric Symptoms
inferred← citeshttps://doi.org/10.1007/978-1-4939-9837-1_15openalex-snapshot
Strategies for Behaviorally Phenotyping the Transgenic Mouse
inferred← citeshttps://doi.org/10.1007/978-1-59259-165-7_1openalex-snapshot
Developmental Neurotoxicology
inferred← citeshttps://doi.org/10.1007/978-1-60761-474-6_4openalex-snapshot
GABAA Receptor α1 Subunit (Gabra1) Knockout Mice: Review and New Results
inferred← citeshttps://doi.org/10.1007/978-1-60761-898-0_8openalex-snapshot
Behavioral Validation in Animal Models of Dementia
inferred← citeshttps://doi.org/10.1007/978-3-030-73317-9_116-1openalex-snapshot
Dose Range Finding (DRF) Studies in Drug Toxicology Assessments
inferred← citeshttps://doi.org/10.1007/978-3-030-73317-9_146-1openalex-snapshot
Juvenile Rodents, Dogs, and NHPs in Safety Pharmacology Studies
inferred← citeshttps://doi.org/10.1007/978-3-030-73317-9_29-1openalex-snapshot
Safety Pharmacology Study Design and Statistics
inferred← citeshttps://doi.org/10.1007/978-3-030-73317-9_3-1openalex-snapshot
Central Nervous System (CNS) Safety Pharmacology Studies
inferred← citeshttps://doi.org/10.1007/978-3-030-73317-9_53-1openalex-snapshot
Drug Safety Assessment
inferred← citeshttps://doi.org/10.1007/978-3-031-35529-5_116openalex-snapshot
Dose Range Finding (DRF) Studies in Drug Toxicology Assessments
inferred← citeshttps://doi.org/10.1007/978-3-031-35529-5_146openalex-snapshot
Juvenile Rodents, Dogs, and NHPs in Safety Pharmacology Studies
inferred← citeshttps://doi.org/10.1007/978-3-031-35529-5_29openalex-snapshot
Safety Pharmacology Study Design and Statistics
inferred← citeshttps://doi.org/10.1007/978-3-031-35529-5_3openalex-snapshot
Central Nervous System (CNS) Safety Pharmacology Studies
inferred← citeshttps://doi.org/10.1007/978-3-0348-7161-7_6openalex-snapshot
Developments in anticonvulsants
inferred← citeshttps://doi.org/10.1007/978-3-319-05392-9_26openalex-snapshot
Effects on Behavior and Muscle Coordination
inferred← citeshttps://doi.org/10.1007/978-3-642-25240-2_29openalex-snapshot
Study Design and Statistics
inferred← citeshttps://doi.org/10.1007/978-3-642-25240-2_3openalex-snapshot
Central Nervous System (CNS) Safety Pharmacology Studies
inferred← citeshttps://doi.org/10.1007/978-3-642-27728-3_26-1openalex-snapshot
Effects on Behavior and Muscle Coordination
inferred← citeshttps://doi.org/10.1007/978-3-642-51624-5_6openalex-snapshot
Comparison of Various Solvent Extractions for the Chromatographic Analysis of Δ9-THC and Its Metabolites
inferred← citeshttps://doi.org/10.1007/978-3-642-68511-8_45openalex-snapshot
Statistical Analysis of Behavioral Toxicology Data and Studies
inferred← citeshttps://doi.org/10.1007/978-3-642-69518-6_12openalex-snapshot
Animal Experimental Methods in the Study of Antiepileptic Drugs
inferred← citeshttps://doi.org/10.1007/978-3-642-69928-3_99openalex-snapshot
Grip Strength Test and Infrared Thermometry as Non-Invasive Methods to Complement Acute Toxicity Data in Mice
inferred← citeshttps://doi.org/10.1007/978-3-642-71499-3_26openalex-snapshot
Iloprost in Experimental Cerebral Ischemia
inferred← citeshttps://doi.org/10.1007/978-3-642-74117-3_74openalex-snapshot
Effects of Carbamates upon Various Behavioural Parameters in Mice
inferred← citeshttps://doi.org/10.1007/978-3-642-74337-5_167openalex-snapshot
Neurophysiologic Assessment of Neural Tolerance of a New Paramagnetic Complex
inferred← citeshttps://doi.org/10.1007/978-3-642-75840-9_16openalex-snapshot
Structure and Functions of the Histaminergic Neurone System
inferred← citeshttps://doi.org/10.1007/978-3-642-81919-3_10openalex-snapshot
Behavioral Testing Procedures: A Review
inferred← citeshttps://doi.org/10.1007/978-3-662-03333-3_5openalex-snapshot
Psychotropic and neurotropic activity
inferred← citeshttps://doi.org/10.1007/978-3-662-46943-9_4openalex-snapshot
CNS Adverse Effects: From Functional Observation Battery/Irwin Tests to Electrophysiology
inferred← citeshttps://doi.org/10.1007/978-3-7091-6833-2_30openalex-snapshot
Comparison of alternatives to Freund’s Complete Adjuvant
inferred← citeshttps://doi.org/10.1007/978-981-33-4141-8_10openalex-snapshot
Screening of Herbal Medicines for Neurotoxicity: Principles and Methods
inferred← citeshttps://doi.org/10.1007/bf00277811openalex-snapshot
Neurobehavioral tests in single- and repeated-dose toxicity studies in small rodents
inferred← citeshttps://doi.org/10.1007/bf00316255openalex-snapshot
Studies on the role of central catecholaminergic mechanisms in the antidotal effect of the oxime HI 6 in soman poisoned mice
inferred← citeshttps://doi.org/10.1007/bf00402085openalex-snapshot
Uses and limitations of photocell activity cages for assessing effects of drugs
inferred← citeshttps://doi.org/10.1007/bf00404371openalex-snapshot
Drug effects on distress-evoked behavior in mice: Methodology and drug class comparisons
inferred← citeshttps://doi.org/10.1007/bf00429059openalex-snapshot
The effect of tryptophan and a tryptophan/5-hydroxytryptophan combination on indoles in the brains of rats fed a tryptophan deficient diet
inferred← citeshttps://doi.org/10.1007/bf00432229openalex-snapshot
The modifying influence of aging on behavior in mice neonatally injected with monosodium glutamate
inferred← citeshttps://doi.org/10.1007/bf00470579openalex-snapshot
Benzodiazepine antagonist Ro 15-1788: Neurological and behavioral effects
inferred← citeshttps://doi.org/10.1007/bf00555207openalex-snapshot
Behavioral effects of cyclazocine on rats assessed in the open field and residential maze
inferred← citeshttps://doi.org/10.1007/bf00735888openalex-snapshot
Antidepressant-like effects of triiodothyroacetic acid in mice
inferred← citeshttps://doi.org/10.1007/bf00964149openalex-snapshot
Effect of intraventricularly injected ricin on protein synthesis in rat brain
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