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Hypoxia and cancer

https://doi.org/10.1007/s00109-007-0281-3
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1 of the 61 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-21): 10.1038/nature04695 (notice 2020-03-18).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ijc.22436openalex-snapshot
HIF‐1α and CA IX staining in invasive breast carcinomas: Prognosis and treatment outcome
inferredcites →https://doi.org/10.1007/s10555-007-9056-0openalex-snapshot
Hypoxia and radiotherapy: opportunities for improved outcomes in cancer treatment
inferredcites →https://doi.org/10.1007/s10555-007-9059-xopenalex-snapshot
Targeting hypoxia cell signaling for cancer therapy
inferredcites →https://doi.org/10.1007/s10555-007-9060-4openalex-snapshot
Effects of hypoxia on tumor metabolism
inferredcites →https://doi.org/10.1007/s10555-007-9062-2openalex-snapshot
Hypoxia-driven selection of the metastatic phenotype
inferredcites →https://doi.org/10.1007/s10555-007-9063-1openalex-snapshot
Hypoxia, gene expression, and metastasis
inferredcites →https://doi.org/10.1007/s10555-007-9064-0openalex-snapshot
Regulation of tumor pH and the role of carbonic anhydrase 9
inferredcites →https://doi.org/10.1016/0092-8674(89)90901-xopenalex-snapshot
Molecular cloning, primary structure, and expression of the human growth factor-activatable antiporter
inferredcites →https://doi.org/10.1016/j.bbrc.2005.08.111openalex-snapshot
Signalling hypoxia by HIF hydroxylases
inferredcites →https://doi.org/10.1016/j.ccr.2006.04.023openalex-snapshot
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
inferredcites →https://doi.org/10.1016/j.ccr.2007.07.006openalex-snapshot
HIF and c-Myc: Sibling Rivals for Control of Cancer Cell Metabolism and Proliferation
inferredcites →https://doi.org/10.1016/j.cell.2007.01.047openalex-snapshot
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
inferredcites →https://doi.org/10.1016/j.cmet.2006.01.012openalex-snapshot
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
inferredcites →https://doi.org/10.1016/j.cmet.2006.02.002openalex-snapshot
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
inferredcites →https://doi.org/10.1016/j.febslet.2007.06.018openalex-snapshot
Oxygen, a source of life and stress
inferredcites →https://doi.org/10.1016/j.semradonc.2004.04.004openalex-snapshot
Lactate: mirror and motor of tumor malignancy
inferredcites →https://doi.org/10.1016/j.semradonc.2004.04.008openalex-snapshot
Tumor microenvironmental physiology and its implications for radiation oncology
inferredcites →https://doi.org/10.1016/j.tcb.2006.10.002openalex-snapshot
ARDent about acetylation and deacetylation in hypoxia signalling
inferredcites →https://doi.org/10.1016/j.tips.2006.09.002openalex-snapshot
Targeting tumor-associated carbonic anhydrase IX in cancer therapy
inferredcites →https://doi.org/10.1016/s0002-9440(10)64038-2openalex-snapshot
Expression of Hypoxia-Inducible Cell-Surface Transmembrane Carbonic Anhydrases in Human Cancer
inferredcites →https://doi.org/10.1016/s0074-7696(04)42004-xopenalex-snapshot
The Hypoxia-Inducible Factor and Tumor Progression Along the Angiogenic Pathway
inferredcites →https://doi.org/10.1016/s0305-7372(03)00106-3openalex-snapshot
Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy
inferredcites →https://doi.org/10.1016/s1040-8428(02)00135-xopenalex-snapshot
Angiogenesis in hematologic malignancies
inferredcites →https://doi.org/10.1016/s1359-6349(08)71238-2openalex-snapshot
Hypoxia-induced autophagy is mediated through the HIF-induction of BNIP3 and BNIP3L via their BH3-domains
inferredcites →https://doi.org/10.1023/b:canc.0000031768.89246.d7openalex-snapshot
Hypoxic gene expression and metastasis
inferredcites →https://doi.org/10.1038/35036100openalex-snapshot
Cancer: looking outside the genome
inferredcites →https://doi.org/10.1038/nature04483openalex-snapshot
Angiogenesis as a therapeutic target
inferredcites →https://doi.org/10.1038/nature04695openalex-snapshot
Lysyl oxidase is essential for hypoxia-induced metastasis
inferredcites →https://doi.org/10.1038/nature04871openalex-snapshot
Hypoxia signalling in cancer and approaches to enforce tumour regression
inferredcites →https://doi.org/10.1038/nature05985openalex-snapshot
The common biology of cancer and ageing
inferredcites →https://doi.org/10.1038/nrc1187openalex-snapshot
Targeting HIF-1 for cancer therapy
inferredcites →https://doi.org/10.1038/nrc1713openalex-snapshot
The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis
inferredcites →https://doi.org/10.1038/nrc1781openalex-snapshot
Predicting the future burden of cancer
inferredcites →https://doi.org/10.1038/nrc1784openalex-snapshot
Epidemiology — identifying the causes and preventability of cancer?
inferredcites →https://doi.org/10.1038/nrc2152openalex-snapshot
Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition
inferredcites →https://doi.org/10.1038/nrm1366openalex-snapshot
Oxygen sensing by HIF hydroxylases
inferredcites →https://doi.org/10.1038/nrm2239openalex-snapshot
Self-eating and self-killing: crosstalk between autophagy and apoptosis
inferredcites →https://doi.org/10.1038/sj.bjc.6602828openalex-snapshot
Angiogenesis and hypoxia in lymph node metastases is predicted by the angiogenesis and hypoxia in the primary tumour in patients with breast cancer
inferredcites →https://doi.org/10.1038/sj.bjc.6603530openalex-snapshot
Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer
inferredcites →https://doi.org/10.1038/sj.emboj.7601689openalex-snapshot
Functional and physical interaction between Bcl‐XL and a BH3‐like domain in Beclin‐1
inferredcites →https://doi.org/10.1038/sj.onc.1208305openalex-snapshot
Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2α in von Hippel–Lindau renal cell carcinoma
inferredcites →https://doi.org/10.1038/sj.onc.1209597openalex-snapshot
Glycolysis inhibition for anticancer treatment
inferredcites →https://doi.org/10.1038/sj.onc.1210795openalex-snapshot
The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2α
inferredcites →https://doi.org/10.1042/bj20070389openalex-snapshot
Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1
inferredcites →https://doi.org/10.1042/bse0430001openalex-snapshot
Oxygen sensing and hypoxia-induced responses
inferredcites →https://doi.org/10.1074/jbc.275.1.1openalex-snapshot
The Expanding Family of Eucaryotic Na+/H+Exchangers
inferredcites →https://doi.org/10.1074/jbc.m503081200openalex-snapshot
Transport Activity of MCT1 Expressed in Xenopus Oocytes Is Increased by Interaction with Carbonic Anhydrase
inferredcites →https://doi.org/10.1074/jbc.m511397200openalex-snapshot
The Plasma Membrane Lactate Transporter MCT4, but Not MCT1, Is Up-regulated by Hypoxia through a HIF-1α-dependent Mechanism
inferredcites →https://doi.org/10.1074/jbc.m608261200openalex-snapshot
Evidence against a Direct Interaction between Intracellular Carbonic Anhydrase II and Pure C-terminal Domains of SLC4 Bicarbonate Transporters
inferredcites →https://doi.org/10.1128/mcb.00440-07openalex-snapshot
Hypoxia-Inducible Factor 1 and Dysregulated c-Myc Cooperatively Induce Vascular Endothelial Growth Factor and Metabolic Switches Hexokinase 2 and Pyruvate Dehydrogenase Kinase 1
inferredcites →https://doi.org/10.1152/ajpcell.00157.2007openalex-snapshot
Interactions of transmembrane carbonic anhydrase, CAIX, with bicarbonate transporters
inferredcites →https://doi.org/10.1152/ajplung.00528.2005openalex-snapshot
HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes
inferredcites →https://doi.org/10.1158/0008-5472.can-05-3850openalex-snapshot
Exploring a New Twist on Tumor Metastasis
inferredcites →https://doi.org/10.1158/0008-5472.can-05-4564openalex-snapshot
The Oxygen Sensor Factor-Inhibiting Hypoxia-Inducible Factor-1 Controls Expression of Distinct Genes through the Bifunctional Transcriptional Character of Hypoxia-Inducible Factor-1α
inferredcites →https://doi.org/10.1158/1078-0432.ccr-0002-4openalex-snapshot
Positron Emission Tomography-Based Molecular Imaging in Human Cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-04-0076openalex-snapshot
BNIP3 Expression Is Linked with Hypoxia-Regulated Protein Expression and with Poor Prognosis in Non–Small Cell Lung Cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-06-1466openalex-snapshot
BNIP3 as a Progression Marker in Primary Human Breast Cancer; Opposing Functions inIn situVersus Invasive Cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-06-1865openalex-snapshot
The von Hippel-Lindau Tumor Suppressor Protein and Clear Cell Renal Carcinoma
inferredcites →https://doi.org/10.1158/1078-0432.ccr-0688-3openalex-snapshot
Hypoxia and Glucose Metabolism in Malignant Tumors
inferredcites →https://doi.org/10.1158/1535-7163.mct-06-0024openalex-snapshot
Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics
inferredcites →https://doi.org/10.1182/blood-2004-07-2958openalex-snapshot
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4110908openalex-extracted
Dual Stimuli Responsive Nanoparticle Conjugates for Hypoxia Targeted Drug Delivery
inferred← citeshttps://doi.org/10.2139/ssrn.4795031openalex-extracted
Into the Blue: Evolutionary Adaptations Associated with the Diversification of Baleen Whales
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Biosensors for Optimal Tissue Engineering: Recent Developments and Shaping the Future
inferred← citeshttps://doi.org/10.1002/adfm.201801783openalex-snapshot
A Versatile Pt‐Based Core–Shell Nanoplatform as a Nanofactory for Enhanced Tumor Therapy
inferred← citeshttps://doi.org/10.1002/adhm.201800391openalex-snapshot
“Smart” Nanoprobes for Visualization of Tumor Microenvironments
inferred← citeshttps://doi.org/10.1002/adhm.201800819openalex-snapshot
A Core–Shell Nanoplatform for Synergistic Enhanced Sonodynamic Therapy of Hypoxic Tumor via Cascaded Strategy
inferred← citeshttps://doi.org/10.1002/adhm.202202467openalex-snapshot
Dual “Unlocking” Strategy to Overcome Inefficient Nanomedicine Delivery and Tumor Hypoxia for Enhanced Photodynamic‐Immunotherapy
inferred← citeshttps://doi.org/10.1002/adhm.202401451openalex-snapshot
Metal‐Coordinated Polydopamine Structures for Tumor Imaging and Therapy
inferred← citeshttps://doi.org/10.1002/adma.201601710openalex-snapshot
DNA‐Nanostructure–Gold‐Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy
inferred← citeshttps://doi.org/10.1002/adtp.201800026openalex-snapshot
Recent Progress in the Design of Hypoxia‐Specific Nano Drug Delivery Systems for Cancer Therapy
inferred← citeshttps://doi.org/10.1002/advs.201500155openalex-snapshot
Multifunctional Phosphorescent Conjugated Polymer Dots for Hypoxia Imaging and Photodynamic Therapy of Cancer Cells
inferred← citeshttps://doi.org/10.1002/advs.202003129openalex-snapshot
Proteinaceous Hydrogels for Bioengineering Advanced 3D Tumor Models
inferred← citeshttps://doi.org/10.1002/anbr.202200103openalex-snapshot
Hemoglobin‐Related Biomaterials and their Applications
inferred← citeshttps://doi.org/10.1002/bit.25572openalex-snapshot
Application of a fluorescence resonance energy transfer (FRET)‐based biosensor for detection of drug‐induced apoptosis in a 3D breast tumor model
inferred← citeshttps://doi.org/10.1002/cam4.349openalex-snapshot
Restoring physiological levels of ascorbate slows tumor growth and moderates HIF‐1 pathway activity in Gulo−/− mice
inferred← citeshttps://doi.org/10.1002/cam4.70073openalex-snapshot
Potentially functional variants of ERRFI1 in hypoxia‐related genes predict survival of non‐small cell lung cancer patients
inferred← citeshttps://doi.org/10.1002/cbf.3229openalex-snapshot
From obesity to cancer: a review on proposed mechanisms
inferred← citeshttps://doi.org/10.1002/cbf.3983openalex-snapshot
Aglycemia induces apoptosis under hypoxic conditions in A549 cells
inferred← citeshttps://doi.org/10.1002/cmdc.201200502openalex-snapshot
Synthesis and Biological Evaluation of Diaryl‐Substituted Carboranes as Inhibitors of Hypoxia Inducible Factor (HIF)‐1 Transcriptional Activity
inferred← citeshttps://doi.org/10.1002/cncr.24303openalex-snapshot
Prognostic significance of carbonic anhydrase IX expression by cancer‐associated fibroblasts in lung adenocarcinoma
inferred← citeshttps://doi.org/10.1002/hed.21877openalex-snapshot
Targeting tumor hypoxia in nasopharyngeal carcinoma
inferred← citeshttps://doi.org/10.1002/hlca.202200066openalex-snapshot
The Phenazine Scaffold Used as Cytotoxic Pharmacophore Applied in Bactericidal, Antiparasitic and Antitumor Agents
inferred← citeshttps://doi.org/10.1002/iub.2275openalex-snapshot
How hypoxia regulate exosomes in ischemic diseases and cancer microenvironment?
inferred← citeshttps://doi.org/10.1002/jbm.a.34637openalex-snapshot
Impact of the biophysical features of a 3D gelatin microenvironment on glioblastoma malignancy
inferred← citeshttps://doi.org/10.1002/jbm.b.33214openalex-snapshot
An innovative three‐dimensional gelatin foam culture system for improved study of glioblastoma stem cell behavior
inferred← citeshttps://doi.org/10.1002/jbt.21883openalex-snapshot
Quercetin inhibits sodium nitrite‐induced inflammation and apoptosis in different rats organs by suppressing Bax, HIF1‐α, TGF‐β, Smad‐2, and AKT pathways
inferred← citeshttps://doi.org/10.1002/jcp.22400openalex-snapshot
pH control mechanisms of tumor survival and growth
inferred← citeshttps://doi.org/10.1002/jcp.24420openalex-snapshot
Autophagy and senescence in cancer therapy
inferred← citeshttps://doi.org/10.1002/jcp.26232openalex-snapshot
Clinical and prognostic value of the C‐Met/HGF signaling pathway in cervical cancer
inferred← citeshttps://doi.org/10.1002/jlcr.3060openalex-snapshot
Biodistribution of 99mTc‐sunitinib as a potential radiotracer for tumor hypoxia imaging
inferred← citeshttps://doi.org/10.1002/jms.4376openalex-snapshot
Treasure hunt for peptides with undefined chemical modifications: Proteomics identification of differential albumin adducts of 2‐nitroimidazole‐indocyanine green in hypoxic tumor
inferred← citeshttps://doi.org/10.1002/jso.23353openalex-snapshot
Novel focal adhesion protein kindlin‐2 promotes the invasion of gastric cancer cells through phosphorylation of integrin β1 and β3
inferred← citeshttps://doi.org/10.1002/jso.27354openalex-snapshot
The dynamic microenvironment associated with metastatic bone disease: Current concepts
inferred← citeshttps://doi.org/10.1002/mc.22674openalex-snapshot
Long noncoding RNA HAS2‐AS1 mediates hypoxia‐induced invasiveness of oral squamous cell carcinoma
inferred← citeshttps://doi.org/10.1002/mds3.10064openalex-snapshot
Portable, low‐cost hypoxia chamber for simulating hypoxic environments: Development, characterization and applications
inferred← citeshttps://doi.org/10.1002/mnfr.201200424openalex-snapshot
Apigenin and its impact on gastrointestinal cancers
inferred← citeshttps://doi.org/10.1002/nbm.4680openalex-snapshot
VERDICT MRI for radiation treatment response assessment in neuroendocrine tumors
inferred← citeshttps://doi.org/10.1002/pmic.200900537openalex-snapshot
Identification of candidate biomarkers with cancer‐specific glycosylation in the tissue and serum of endometrioid ovarian cancer patients by glycoproteomic analysis
inferred← citeshttps://doi.org/10.1002/ptr.5819openalex-snapshot
C-Glycosyl Flavonoids fromBeta vulgarisCiclaand Betalains fromBeta vulgarisrubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review
inferred← citeshttps://doi.org/10.1002/slct.202102895openalex-snapshot
Small Molecule Fluorescent Probes for Sensing and Bioimaging of Nitroreductase
inferred← citeshttps://doi.org/10.1002/smll.201703045openalex-snapshot
Photosensitive Nanoparticles Combining Vascular‐Independent Intratumor Distribution and On‐Demand Oxygen‐Depot Delivery for Enhanced Cancer Photodynamic Therapy
inferred← citeshttps://doi.org/10.1002/stem.2763openalex-snapshot
Human Mesenchymal Stem Cell Failure to Adapt to Glucose Shortage and Rapidly Use Intracellular Energy Reserves Through Glycolysis Explains Poor Cell Survival After Implantation
inferred← citeshttps://doi.org/10.1002/tox.24009openalex-snapshot
The single‐cell evolution trajectory presented different hypoxia heterogeneity to reveal the carcinogenesis of genes in clear cell renal cell carcinoma: Based on multiple omics and real experimental verification
inferred← citeshttps://doi.org/10.1002/wnan.1702openalex-snapshot
Cancer‐associated‐platelet‐inspired nanomedicines for cancer therapy
inferred← citeshttps://doi.org/10.1007/16833_2022_56openalex-snapshot
Advanced 3D In Vitro Models to Recapitulate the Breast Tumor Microenvironment
inferred← citeshttps://doi.org/10.1007/978-1-0716-2914-7_17openalex-snapshot
Spheroids as a 3D Model of the Hypoxic Tumor Microenvironment
inferred← citeshttps://doi.org/10.1007/978-1-0716-3633-6_11openalex-snapshot
Staining Hypoxic Areas of Frozen and FFPE Tissue Sections with Hypoxyprobe™
inferred← citeshttps://doi.org/10.1007/978-1-4614-5203-4_12openalex-snapshot
Cardiopulmonary Adaptation to High Altitude
inferred← citeshttps://doi.org/10.1007/978-1-4939-3554-3_1openalex-snapshot
The Biology of Melanoma
inferred← citeshttps://doi.org/10.1007/978-1-59745-435-3openalex-snapshot
Cellular Respiration and Carcinogenesis
inferred← citeshttps://doi.org/10.1007/978-3-319-60511-1_5openalex-snapshot
Three Dimensional In Vitro Tumor Platforms for Cancer Discovery
inferred← citeshttps://doi.org/10.1007/978-94-007-2869-1_19openalex-snapshot
Mitochondrial Proteomic Approaches for New Potential Diagnostic and Prognostic Biomarkers in Cancer
inferred← citeshttps://doi.org/10.1007/978-94-007-7359-2_12openalex-snapshot
Carbonic Anhydrase IX as an Imaging and Therapeutic Target for Tumors and Metastases
inferred← citeshttps://doi.org/10.1007/978-981-16-1846-8_16openalex-snapshot
Autophagy at the Crossroad of Obesity-Mediated Cancer Progression
inferred← citeshttps://doi.org/10.1007/978-981-16-6226-3_7openalex-snapshot
Timing of the Major Metabolic Switches in Immune Cell Activation and Differentiation During Cancer Development
inferred← citeshttps://doi.org/10.1007/978-981-96-1016-7_9openalex-snapshot
Hypoxia-Inducible Factors: Regulation and Therapeutic Potential in Cancer: Artificial Intelligence in Precision Medicine
inferred← citeshttps://doi.org/10.1007/978-981-99-0313-9_16openalex-snapshot
Hypoxia-Targeting Drugs as New Cancer Chemotherapy Agents: Molecular Insights
inferred← citeshttps://doi.org/10.1007/978-981-99-0313-9_2openalex-snapshot
Hypoxia’s Function in Cancer
inferred← citeshttps://doi.org/10.1007/978-981-99-0313-9_3openalex-snapshot
Role of Hypoxia and Reactive Oxygen Species in Cancer Biology
inferred← citeshttps://doi.org/10.1007/s00011-023-01821-0openalex-snapshot
Insights into the complex interactions between Rab22a and extracellular vesicles in cancers
inferred← citeshttps://doi.org/10.1007/s00018-010-0581-6openalex-snapshot
HLA-G in organ transplantation: towards clinical applications
inferred← citeshttps://doi.org/10.1007/s00109-008-0364-9openalex-snapshot
The expanding universe of hypoxia
inferred← citeshttps://doi.org/10.1007/s00109-012-0880-5openalex-snapshot
Nitric oxide signaling in hypoxia
inferred← citeshttps://doi.org/10.1007/s00109-015-1307-xopenalex-snapshot
Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H+ symporters
inferred← citeshttps://doi.org/10.1007/s00280-009-0992-yopenalex-snapshot
Antiangiogenic and antiproliferative effects of substituted-1,3,4-oxadiazole derivatives is mediated by down regulation of VEGF and inhibition of translocation of HIF-1α in Ehrlich ascites tumor cells
inferred← citeshttps://doi.org/10.1007/s00285-022-01850-zopenalex-snapshot
Role of senescent tumor cells in building a cytokine shield in the tumor microenvironment: mathematical modeling
inferred← citeshttps://doi.org/10.1007/s00383-015-3831-8openalex-snapshot
Influence of hypoxia-dependent factors on the progression of neuroblastoma
inferred← citeshttps://doi.org/10.1007/s00394-017-1418-yopenalex-snapshot
Antiproliferative activity of vitexin-2-O-xyloside and avenanthramides on CaCo-2 and HepG2 cancer cells occurs through apoptosis induction and reduction of pro-survival mechanisms
inferred← citeshttps://doi.org/10.1007/s00411-022-00974-6openalex-snapshot
Radiation and chemotherapy variable response induced by tumor cell hypoxia: impact of radiation dose, anticancer drug, and type of cancer
inferred← citeshttps://doi.org/10.1007/s00428-009-0791-1openalex-snapshot
LANA-1, Bcl-2, Mcl-1 and HIF-1α protein expression in HIV-associated Kaposi sarcoma
inferred← citeshttps://doi.org/10.1007/s00428-013-1453-xopenalex-snapshot
In papillary thyroid carcinoma, TIMP-1 expression correlates with BRAF V600E mutation status and together with hypoxia-related proteins predicts aggressive behavior
inferred← citeshttps://doi.org/10.1007/s00701-011-1200-5openalex-snapshot
5-Aminolevulinic acid (5-ALA)-induced fluorescence in intracerebral metastases: a retrospective study
inferred← citeshttps://doi.org/10.1007/s00726-009-0360-6openalex-snapshot
Daily quadratic trend in basal monocyte expressed HSP72 in healthy human subjects
inferred← citeshttps://doi.org/10.1007/s10068-011-0052-3openalex-snapshot
Involvement of AMPK/mTOR/HIF-1α in anticancer control of quercetin in hypoxic MCF-7 cells
inferred← citeshttps://doi.org/10.1007/s10142-022-00956-3openalex-snapshot
Identification of seven hypoxia-related genes signature and risk score models for predicting prognosis for ovarian cancer
inferred← citeshttps://doi.org/10.1007/s10147-016-0983-zopenalex-snapshot
Spectrum of cancer risk among Taiwanese with chronic obstructive pulmonary disease
inferred← citeshttps://doi.org/10.1007/s10439-012-0655-8openalex-snapshot
Multiscale Models of Breast Cancer Progression
inferred← citeshttps://doi.org/10.1007/s10456-012-9291-zopenalex-snapshot
Contrasting effects of sunitinib within in vivo models of metastasis
inferred← citeshttps://doi.org/10.1007/s10456-013-9394-1openalex-snapshot
miR-320 regulates tumor angiogenesis driven by vascular endothelial cells in oral cancer by silencing neuropilin 1
inferred← citeshttps://doi.org/10.1007/s10495-012-0719-0openalex-snapshot
Quercetin enhances hypoxia-mediated apoptosis via direct inhibition of AMPK activity in HCT116 colon cancer
inferred← citeshttps://doi.org/10.1007/s10517-022-05506-2openalex-snapshot
Changes in the Expression of miRNA Isoforms and Their Targets in HT-29 Cells after Hypoxic Exposure
inferred← citeshttps://doi.org/10.1007/s10555-011-9309-9openalex-snapshot
Eicosanoids and other lipid mediators and the tumor hypoxic microenvironment
inferred← citeshttps://doi.org/10.1007/s10555-023-10082-6openalex-snapshot
Insights into the role of senescence in tumor dormancy: mechanisms and applications
inferred← citeshttps://doi.org/10.1007/s10637-009-9356-zopenalex-snapshot
Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation
inferred← citeshttps://doi.org/10.1007/s10695-019-00708-4openalex-snapshot
Dietary GABA enhances hypoxia tolerance of a bottom-dwelling carp, Cirrhinus mrigala by modulating HIF-1α, thyroid hormones and metabolic responses
inferred← citeshttps://doi.org/10.1007/s10719-024-10168-5openalex-snapshot
Emerging role of MAPK signaling in glycosphingolipid-associated tumorigenesis
inferred← citeshttps://doi.org/10.1007/s10751-026-02400-5openalex-snapshot
Monte Carlo simulations of the depth of maximum muon dose in tumors
inferred← citeshttps://doi.org/10.1007/s10895-021-02800-6openalex-snapshot
A Nitronaphthalimide Probe for Fluorescence Imaging of Hypoxia in Cancer Cells
inferred← citeshttps://doi.org/10.1007/s11010-014-2072-9openalex-snapshot
Expression of oxidored nitro domain-containing protein 1(NOR1) impairs nasopharyngeal carcinoma cells adaptation to hypoxia and inhibits PDK1 expression
inferred← citeshttps://doi.org/10.1007/s11033-022-07598-5openalex-snapshot
Differential response of hepatocellular carcinoma glycolytic metabolism and oxidative stress markers after exposure to human amniotic membrane proteins
inferred← citeshttps://doi.org/10.1007/s11051-023-05837-9openalex-snapshot
New era of nanoparticles facilitated co-delivery in cancer therapy: two heads are better than one
inferred← citeshttps://doi.org/10.1007/s11064-011-0620-1openalex-snapshot
Synergistic Effects of Arsenic Trioxide and Silibinin on Apoptosis and Invasion in Human Glioblastoma U87MG Cell Line
inferred← citeshttps://doi.org/10.1007/s11626-015-9970-3openalex-snapshot
In vitro evaluation of anticancer properties of exopolysaccharides from Lactobacillus acidophilus in colon cancer cell lines
inferred← citeshttps://doi.org/10.1007/s11684-013-0301-3openalex-snapshot
The impact of hypoxia in hepatocellular carcinoma metastasis
inferred← citeshttps://doi.org/10.1007/s11756-021-00812-yopenalex-snapshot
Association of genetic polymorphism rs2071676 in carbonic anhydrase gene (CA9) with the risk of squamous cell carcinoma of lungs and esophagus
inferred← citeshttps://doi.org/10.1007/s11805-009-0090-2openalex-snapshot
Expression of mitochondrial transcripts in gastric MGC803 cell line subjected by hypoxia
inferred← citeshttps://doi.org/10.1007/s12029-011-9277-xopenalex-snapshot
Clusterin and Chemotherapy Sensitivity Under Normoxic and Graded Hypoxic Conditions in Colorectal Cancer
inferred← citeshttps://doi.org/10.1007/s12031-022-02090-yopenalex-snapshot
Profiling and Bioinformatics Analyses of Differential Circular RNA Expression in Glioblastoma Multiforme Cells Under Hypoxia
inferred← citeshttps://doi.org/10.1007/s12032-013-0701-xopenalex-snapshot
The expression of LC-3 is related to tumor suppression through angiogenesis in esophageal cancer
inferred← citeshttps://doi.org/10.1007/s12032-022-01871-0openalex-snapshot
Redox balance and autophagy regulation in cancer progression and their therapeutic perspective
inferred← citeshttps://doi.org/10.1007/s12033-024-01203-9openalex-snapshot
Predicting the Prognosis of Bladder Cancer Patients Through Integrated Multi-omics Exploration of Chemotherapy-Related Hypoxia Genes
inferred← citeshttps://doi.org/10.1007/s12094-012-0842-yopenalex-snapshot
Novel antiangiogenic therapies against advanced hepatocellular carcinoma (HCC)
inferred← citeshttps://doi.org/10.1007/s12210-009-0071-7openalex-snapshot
Multicopper oxidases: an innovative approach for oxygen management of aerobic organisms
inferred← citeshttps://doi.org/10.1007/s12272-018-1050-2openalex-snapshot
Synthesis and structure–activity relationship of N-(piperidin-4-yl)benzamide derivatives as activators of hypoxia-inducible factor 1 pathways
inferred← citeshttps://doi.org/10.1007/s12307-011-0067-6openalex-snapshot
The Interrelating Dynamics of Hypoxic Tumor Microenvironments and Cancer Cell Phenotypes in Cancer Metastasis
inferred← citeshttps://doi.org/10.1007/s12307-011-0072-9openalex-snapshot
Angiogenesis and Multiple Myeloma
inferred← citeshttps://doi.org/10.1007/s12672-015-0231-4openalex-snapshot
Pheochromocytoma: Gasping for Air
inferred← citeshttps://doi.org/10.1007/s13204-013-0216-yopenalex-snapshot
Magnetic nanoparticle drug delivery systems for targeting tumor
inferred← citeshttps://doi.org/10.1007/s13277-012-0349-8openalex-snapshot
RNA interference of hypoxia-inducible factor-1 alpha improves the effects of transcatheter arterial embolization in rat liver tumors
inferred← citeshttps://doi.org/10.1007/s13277-014-2112-9openalex-snapshot
Polymorphism in PHD1 gene and risk of non-small cell lung cancer in a Chinese population
inferred← citeshttps://doi.org/10.1007/s13277-015-3508-xopenalex-snapshot
Combretastatin A4 phosphate treatment induces vasculogenic mimicry formation of W256 breast carcinoma tumor in vitro and in vivo
inferred← citeshttps://doi.org/10.1007/s40336-020-00358-0openalex-snapshot
Hypoxia PET imaging beyond 18F-FMISO in patients with high-grade glioma: 18F-FAZA and other hypoxia radiotracers
inferred← citeshttps://doi.org/10.1007/s41061-022-00389-3openalex-snapshot
Phosphorescent Ir(III) Complexes for Biolabeling and Biosensing
inferred← citeshttps://doi.org/10.1016/b978-0-12-394280-7.00006-3openalex-snapshot
Opportunities and Challenges in Tumor Angiogenesis Research
inferred← citeshttps://doi.org/10.1016/b978-0-12-405530-8.00021-2openalex-snapshot
Hypoxia-Induced Autophagy Promotes Tumor Cell Survival
inferred← citeshttps://doi.org/10.1016/b978-0-12-800254-4.00007-6openalex-snapshot
Nitric Oxide and Hypoxia Signaling
inferred← citeshttps://doi.org/10.1016/b978-0-12-819059-3.00002-2openalex-snapshot
Cancer metabolism
inferred← citeshttps://doi.org/10.1016/b978-0-12-822000-9.00007-0openalex-snapshot
Tumor genomics in radiotherapy
inferred← citeshttps://doi.org/10.1016/b978-0-443-31484-1.00004-9openalex-snapshot
Endophytic fungi in anticancer drug development: Targeting tumor microenvironment
inferred← citeshttps://doi.org/10.1016/b978-0-443-33641-6.00015-4openalex-snapshot
Azo-based compounds for hypoxia-responsive drug delivery
inferred← citeshttps://doi.org/10.1016/bs.acr.2021.01.002openalex-snapshot
Autophagy and senescence in cancer therapy
inferred← citeshttps://doi.org/10.1016/bs.ircmb.2015.07.006openalex-snapshot
Ribosomal Protein S6 Phosphorylation
inferred← citeshttps://doi.org/10.1016/j.abb.2013.12.023openalex-snapshot
Minocycline inhibits angiogenesis in vitro through the translational suppression of HIF-1α
inferred← citeshttps://doi.org/10.1016/j.actbio.2019.09.009openalex-snapshot
Tumor microenvironment targeted nanotherapeutics for cancer therapy and diagnosis: A review
inferred← citeshttps://doi.org/10.1016/j.adcanc.2022.100074openalex-snapshot
Insights into therapy resistance in cervical cancer
inferred← citeshttps://doi.org/10.1016/j.advenzreg.2009.10.005openalex-snapshot
Membrane-bound carbonic anhydrases are key pH regulators controlling tumor growth and cell migration
inferred← citeshttps://doi.org/10.1016/j.ajhg.2024.02.012openalex-snapshot
The association of cigarette smoking with DNA methylation and gene expression in human tissue samples
inferred← citeshttps://doi.org/10.1016/j.annpat.2010.07.028openalex-snapshot
Le stress hypoxique et nutritionnel tumoral. Nouvelles approches anticancer
inferred← citeshttps://doi.org/10.1016/j.apsb.2024.09.009openalex-snapshot
Advances and prospects of RNA delivery nanoplatforms for cancer therapy
inferred← citeshttps://doi.org/10.1016/j.bbadis.2023.166894openalex-snapshot
Estrogen receptor β affects hypoxia response in colorectal cancer cells
inferred← citeshttps://doi.org/10.1016/j.bbagen.2019.06.007openalex-snapshot
The biochemical and molecular mechanisms involved in the role of tumor micro-environment stress in development of drug resistance
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2010.11.014openalex-snapshot
Hypoxia-mediated control of HIF/ARNT machinery in epidermal keratinocytes
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2013.02.025openalex-snapshot
MgcRacGAP, a cytoskeleton regulator, inhibits HIF-1 transcriptional activity by blocking its dimerization
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2017.01.010openalex-snapshot
Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1,4,5-triphosphate receptor dependent calcium signaling
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2020.118644openalex-snapshot
Roles for Ca2+ and K+ channels in cancer cells exposed to the hypoxic tumour microenvironment
inferred← citeshttps://doi.org/10.1016/j.bbcan.2009.02.003openalex-snapshot
Considering the role of pyruvate in tumor cells during hypoxia
inferred← citeshttps://doi.org/10.1016/j.bbrc.2009.07.138openalex-snapshot
STAT1 represses hypoxia-inducible factor-1-mediated transcription
inferred← citeshttps://doi.org/10.1016/j.bbrc.2009.09.068openalex-snapshot
Silibinin inhibits expression of HIF-1α through suppression of protein translation in prostate cancer cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2010.12.112openalex-snapshot
Detection of ER stress in vivo by Raman spectroscopy
inferred← citeshttps://doi.org/10.1016/j.bbrc.2011.03.119openalex-snapshot
Hypoxia-inducible factor 1 alpha represses the transcription of the estrogen receptor alpha gene in human breast cancer cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2011.08.058openalex-snapshot
Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2α through hypoxia- and von Hippel–Lindau tumor suppressor protein-independent regulatory mechanisms
inferred← citeshttps://doi.org/10.1016/j.bbrc.2012.03.114openalex-snapshot
Matairesinol inhibits angiogenesis via suppression of mitochondrial reactive oxygen species
inferred← citeshttps://doi.org/10.1016/j.bcp.2016.05.005openalex-snapshot
Adipose extracellular matrix remodelling in obesity and insulin resistance
inferred← citeshttps://doi.org/10.1016/j.bcp.2019.01.004openalex-snapshot
Potentialization of anticancer agents by identification of new chemosensitizers active under hypoxia
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116160openalex-snapshot
Biochemical pharmacology of adenylyl cyclases in cancer
inferred← citeshttps://doi.org/10.1016/j.bej.2023.109205openalex-snapshot
(S)-specific carbonyl reductase from Candida parapsilosis ATCC 7330 as a model for the initial screening of inhibitors for human carbonyl reductase
inferred← citeshttps://doi.org/10.1016/j.biocel.2013.02.018openalex-snapshot
15-Lipoxygenase-1/15-hydroxyeicosatetraenoic acid promotes hepatocellular cancer cells growth through protein kinase B and heat shock protein 90 complex activation
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2011.07.001openalex-snapshot
3D in vitro bioengineered tumors based on collagen I hydrogels
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2014.03.049openalex-snapshot
Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2016.03.002openalex-snapshot
Metabolic response of lung cancer cells to radiation in a paper-based 3D cell culture system
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2018.08.004openalex-snapshot
Hypoxic tumor therapy by hemoglobin-mediated drug delivery and reversal of hypoxia-induced chemoresistance
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2019.119393openalex-snapshot
Tandem activated photodynamic and chemotherapy: Using pH-Sensitive nanosystems to realize different tumour distributions of photosensitizer/prodrug for amplified combination therapy
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.102985openalex-snapshot
Synthesis and in vitro anticancer evaluation of some fused indazoles, quinazolines and quinolines as potential EGFR inhibitors
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.103436openalex-snapshot
Steering the antitumor drug discovery campaign towards structurally diverse indolines
inferred← citeshttps://doi.org/10.1016/j.biopha.2021.111873openalex-snapshot
The role of Hypoxia-Inducible Factor-1alpha and its signaling in melanoma
inferred← citeshttps://doi.org/10.1016/j.bios.2016.04.068openalex-snapshot
Amperometric sensing of HIF1α expressed in cancer cells and the effect of hypoxic mimicking agents
inferred← citeshttps://doi.org/10.1016/j.biosystems.2024.105257openalex-snapshot
What do stimulated beta cells have in common with cancer cells?
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2011.07.006openalex-snapshot
From cancer metabolism to new biomarkers and drug targets
inferred← citeshttps://doi.org/10.1016/j.bmc.2009.08.037openalex-snapshot
Design of a bioreductively-activated fluorescent pH probe for tumor hypoxia imaging
inferred← citeshttps://doi.org/10.1016/j.bmcl.2009.06.022openalex-snapshot
In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives
inferred← citeshttps://doi.org/10.1016/j.bmcl.2011.10.058openalex-snapshot
Synthesis and evaluation of near-infrared fluorescent sulfonamide derivatives for imaging of hypoxia-induced carbonic anhydrase IX expression in tumors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.02.071openalex-snapshot
Development of hypoxia-sensitive Gd3+-based MRI contrast agents
inferred← citeshttps://doi.org/10.1016/j.bpj.2022.04.039openalex-snapshot
Cancer as a biophysical disease: Targeting the mechanical-adaptability program
inferred← citeshttps://doi.org/10.1016/j.breast.2016.09.002openalex-snapshot
Tumor microenvironment-mediated chemoresistance in breast cancer
inferred← citeshttps://doi.org/10.1016/j.canlet.2011.01.008openalex-snapshot
Pentamidine reduces expression of hypoxia-inducible factor-1α in DU145 and MDA-MB-231 cancer cells
inferred← citeshttps://doi.org/10.1016/j.canlet.2011.09.023openalex-snapshot
Hypoxia, stem cells and bone tumor
inferred← citeshttps://doi.org/10.1016/j.canlet.2011.09.039openalex-snapshot
Characterization of a cell culture model for clinically aggressive hepatocellular carcinoma induced by chronic hypoxia
inferred← citeshttps://doi.org/10.1016/j.canlet.2013.01.042openalex-snapshot
Microenvironment and tumor cell plasticity: An easy way out
inferred← citeshttps://doi.org/10.1016/j.canlet.2014.11.020openalex-snapshot
Hypoxia-activated pro-drug TH-302 exhibits potent tumor suppressive activity and cooperates with chemotherapy against osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.canlet.2021.05.031openalex-snapshot
KRAS-dependent cancer cells promote survival by producing exosomes enriched in Survivin
inferred← citeshttps://doi.org/10.1016/j.canlet.2022.216036openalex-snapshot
Extracellular vesicles as a novel approach for breast cancer therapeutics
inferred← citeshttps://doi.org/10.1016/j.canlet.2024.216823openalex-snapshot
Hypoxia-associated autophagy flux dysregulation in human cancers
inferred← citeshttps://doi.org/10.1016/j.cbd.2019.100602openalex-snapshot
Insights into hypoxic adaptation in Tibetan chicken embryos from comparative proteomics
inferred← citeshttps://doi.org/10.1016/j.cbpb.2022.110714openalex-snapshot
Dietary arginine attenuates hypoxia- induced HIF expression, metabolic responses and oxidative stress in Indian Major Carp, Cirrhinus mrigala
inferred← citeshttps://doi.org/10.1016/j.ccr.2009.02.007openalex-snapshot
Silencing or Fueling Metastasis with VEGF Inhibitors: Antiangiogenesis Revisited
inferred← citeshttps://doi.org/10.1016/j.ccr.2011.07.008openalex-snapshot
A Cullin3-KLHL20 Ubiquitin Ligase-Dependent Pathway Targets PML to Potentiate HIF-1 Signaling and Prostate Cancer Progression
inferred← citeshttps://doi.org/10.1016/j.cej.2025.161735openalex-snapshot
Biomimetic nanoadjuvant-enhanced ultrasound-induced STING activation potentiates aPD-L1 therapy to overcome cancer recurrence and metastasis
inferred← citeshttps://doi.org/10.1016/j.cell.2023.11.006openalex-snapshot
Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors
inferred← citeshttps://doi.org/10.1016/j.cis.2021.102509openalex-snapshot
Recent advances in active targeting of nanomaterials for anticancer drug delivery
inferred← citeshttps://doi.org/10.1016/j.compbiolchem.2019.04.011openalex-snapshot
DFT-based QSAR modelling of selectivity and inhibitory activity of coumarins and sulfocoumarins against tumor-associated carbonic anhydrase isoform IX
inferred← citeshttps://doi.org/10.1016/j.compbiolchem.2025.108708openalex-snapshot
Designing & screening of siRNA molecules for silencing the impact of the VEGF gene in cancer cells
inferred← citeshttps://doi.org/10.1016/j.coph.2020.07.005openalex-snapshot
Oxygenation and A2AR blockade to eliminate hypoxia/HIF-1α-adenosinergic immunosuppressive axis and improve cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.cpt.2025.07.003openalex-snapshot
Investigating hypoxia-inducible factor signaling in cancer: Mechanisms, clinical implications, targeted therapeutic strategies, and resistance
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2015.02.009openalex-snapshot
Angiogenic inhibitors in gastric cancers and gastroesophageal junction carcinomas: A critical insight
inferred← citeshttps://doi.org/10.1016/j.cyto.2010.06.012openalex-snapshot
Vascular endothelial growth factor inhibition: Conflicting roles in tumor growth
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2009.11.003openalex-snapshot
Pathways mediating VEGF-independent tumor angiogenesis
inferred← citeshttps://doi.org/10.1016/j.ejca.2009.07.010openalex-snapshot
Drug-metabolising enzymes are down-regulated by hypoxia in differentiated human hepatoma HepaRG cells: HIF-1α involvement in CYP3A4 repression
inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.113837openalex-snapshot
Sulfonamide derivatives as potential anti-cancer agents and their SARs elucidation
inferred← citeshttps://doi.org/10.1016/j.ejmech.2025.118304openalex-snapshot
Click-modifiable isatin hydrazones as COX-2, VEGFR-2, and carbonic anhydrase inhibitors: A multi-target approach to cancer therapy
inferred← citeshttps://doi.org/10.1016/j.ejphar.2022.174845openalex-snapshot
Suppression of the doxorubicin response by hypoxia-inducible factor-1α is strictly dependent on oxygen concentrations under hypoxic conditions
inferred← citeshttps://doi.org/10.1016/j.expneurol.2015.02.003openalex-snapshot
CXCR3: Latest evidence for the involvement of chemokine signaling in bone cancer pain
inferred← citeshttps://doi.org/10.1016/j.fct.2011.02.008openalex-snapshot
A study of anti-cancer effects of Funalia trogii in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2010.02.013openalex-snapshot
Reactive oxygen species produced by the knockdown of manganese-superoxide dismutase up-regulate hypoxia-inducible factor-1α expression in oral squamous cell carcinoma cells
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2026.07.041openalex-snapshot
Physiologically relevant oxygen tensions reshape anticancer responses under oxidative stress-permissive culture conditions
inferred← citeshttps://doi.org/10.1016/j.gene.2013.03.129openalex-snapshot
1790 G/A polymorphism, but not 1772 C/T polymorphism, is significantly associated with Cancers: An update study
inferred← citeshttps://doi.org/10.1016/j.gene.2020.144552openalex-snapshot
Hypoxia-induced elevated NDRG1 mediates apoptosis through reprograming mitochondrial fission in HCC
inferred← citeshttps://doi.org/10.1016/j.gene.2021.145796openalex-snapshot
Up-down regulation of HIF-1α in cancer progression
inferred← citeshttps://doi.org/10.1016/j.gene.2024.149047openalex-snapshot
Effect of epigenetic changes in hypoxia induced factor (HIF) gene across cancer types
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