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An overview of the cytochrome P450 enzymes that catalyze the same-site multistep oxidation reactions in biotechnologically relevant selected actinomycete strains
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Enzymatic C−H Oxidation–Amidation Cascade in the Production of Natural and Unnatural Thiotetronate Antibiotics with Potentiated Bioactivity
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Dissection of the Late Steps in Aureothin Biosynthesis
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Identification of the Tirandamycin Biosynthetic Gene Cluster from Streptomyces sp. 307‐9
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Cloning and Characterization of the Biosynthetic Gene Cluster of 16‐Membered Macrolide Antibiotic FD‐891: Involvement of a Dual Functional Cytochrome P450 Monooxygenase Catalyzing Epoxidation and Hydroxylation
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Pyran Formation by an Atypical CYP‐Mediated Four‐Electron Oxygenation–Cyclization Cascade in an Engineered Aureothin Pathway
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Substrate Recognition by a Dual‐Function P450 Monooxygenase GfsF Involved in FD‐891 Biosynthesis
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Moonlighting cytochrome P450 monooxygenases
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Mechanisms of cytochrome P450 substrate oxidation: MiniReview
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Molecular characterization of cytochrome P450 genes in the polycyclic aromatic hydrocarbon degrading Mycobacterium vanbaalenii PYR-1
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Engineered biosynthesis of pimaricin derivatives with improved antifungal activity and reduced cytotoxicity
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Generation of tetramycin B derivative with improved pharmacological property based on pathway engineering
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Artificial control of the multistep oxidation reactions catalyzed by the cytochrome P450 enzyme RosC
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Production of rosamicin derivatives in Micromonospora rosaria by introduction of d-mycinose biosynthetic gene with ΦC31-derived integration vector pSET152
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A new mycinosyl rosamicin derivative produced by an engineered Micromonospora rosaria mutant with a cytochrome P450 gene disruption introducing the d -mycinose biosynthetic gene
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Multi-step oxidations catalyzed by cytochrome P450 enzymes: Processive vs. distributive kinetics and the issue of carbonyl oxidation in chemical mechanisms
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Applications of microbial cytochrome P450 enzymes in biotechnology and synthetic biology
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Production of Hybrid 16-Membered Macrolides by Expressing Combinations of Polyketide Synthase Genes in Engineered Streptomyces fradiae Hosts
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A Tailoring Activity Is Responsible for Generating Polyene Amide Derivatives in Streptomyces diastaticus var. 108
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Functional Analysis of MycCI and MycG, Cytochrome P450 Enzymes Involved in Biosynthesis of Mycinamicin Macrolide Antibiotics
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A review of mechanistic studies on aromatase (CYP19) and 17α-hydroxylase-17,20-lyase (CYP17)
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Self-resistance mechanism in Streptomyces peucetius: Overexpression of drrA, drrB and drrC for doxorubicin enhancement
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Actinobacteria in natural products research: Progress and prospects
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Cytochrome P450 Monooxygenases in Biotechnology and Synthetic Biology
inferredcites →https://doi.org/10.1016/s0021-9258(18)82129-9openalex-snapshot
FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818
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Mechanism of androstenedione formation from testosterone and epitestosterone catalyzed by purified cytochrome P-450b.
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The Structures of Four Macrolide Antibiotics Bound to the Large Ribosomal Subunit
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Solution Conformations and Dynamics of Substrate-Bound Cytochrome P450 MycG
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Mechanistic Insights into Interactions between Bacterial Class I P450 Enzymes and Redox Partners
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Mechanistic Insights into the Directing Effect of Thr303 in Ethanol Oxidation by Cytochrome P450 2E1
inferredcites →https://doi.org/10.1021/ar500242copenalex-snapshot
Highly Selective but Multifunctional Oxygenases in Secondary Metabolism
inferredcites →https://doi.org/10.1021/bi973076popenalex-snapshot
NADPH−Flavodoxin Reductase and Flavodoxin fromEscherichia coli: Characteristics as a Soluble Microsomal P450 Reductase
inferredcites →https://doi.org/10.1021/cr0406110openalex-snapshot
Biosynthetic and Biomimetic Electrocyclizations
inferredcites →https://doi.org/10.1021/ja046104hopenalex-snapshot
Formation of the Aureothin Tetrahydrofuran Ring by a Bifunctional Cytochrome P450 Monooxygenase
inferredcites →https://doi.org/10.1021/ja0639214openalex-snapshot
Pentalenolactone Biosynthesis. Molecular Cloning and Assignment of Biochemical Function to PtlI, a Cytochrome P450 of Streptomyces avermitilis
inferredcites →https://doi.org/10.1021/ja110146zopenalex-snapshot
Structural Fine-Tuning of a Multifunctional Cytochrome P450 Monooxygenase
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Computational-Based Mechanistic Study and Engineering of Cytochrome P450 MycG for Selective Oxidation of 16-Membered Macrolide Antibiotics
inferredcites →https://doi.org/10.1021/np4001224openalex-snapshot
Characterization of FK506 Biosynthetic Intermediates Involved in Post-PKS Elaboration
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Borrelidin B: Isolation, Biological Activity, and Implications for Nitrile Biosynthesis
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Isolation and Characterization of Tirandamycins from a Marine-Derived Streptomyces sp.
inferredcites →https://doi.org/10.1021/ol302782uopenalex-snapshot
Carboxyl Formation from Methyl via Triple Hydroxylations by XiaM in Xiamycin A Biosynthesis
inferredcites →https://doi.org/10.1038/ja.2010.38openalex-snapshot
Isolation and characterization of 23-O-mycinosyl-20-dihydro-rosamicin: a new rosamicin analogue derived from engineered Micromonospora rosaria
inferredcites →https://doi.org/10.1038/ja.2012.27openalex-snapshot
Thoughts and facts about antibiotics: Where we are now and where we are heading
inferredcites →https://doi.org/10.1038/nchem.1087openalex-snapshot
Tirandamycin biosynthesis is mediated by co-dependent oxidative enzymes
inferredcites →https://doi.org/10.1039/c3cc45982aopenalex-snapshot
Labelling studies on the biosynthesis of terpenes in Fusarium fujikuroi
inferredcites →https://doi.org/10.1039/c7np00034kopenalex-snapshot
Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function
inferredcites →https://doi.org/10.1039/c7np00063dopenalex-snapshot
Unrivalled diversity: the many roles and reactions of bacterial cytochromes P450 in secondary metabolism
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Selective oxidation of aliphatic C–H bonds in alkylphenols by a chemomimetic biocatalytic system
inferredcites →https://doi.org/10.1074/jbc.m109.064683openalex-snapshot
Crystal Structure of Albaflavenone Monooxygenase Containing a Moonlighting Terpene Synthase Active Site
inferredcites →https://doi.org/10.1074/jbc.m112.410340openalex-snapshot
Substrate Recognition by the Multifunctional Cytochrome P450 MycG in Mycinamicin Hydroxylation and Epoxidation Reactions
inferredcites →https://doi.org/10.1074/jbc.m115.695320openalex-snapshot
Characterization of a Unique Pathway for 4-Cresol Catabolism Initiated by Phosphorylation in Corynebacterium glutamicum
inferredcites →https://doi.org/10.1074/jbc.m506689200openalex-snapshot
Biosynthesis of Amphotericin Derivatives Lacking Exocyclic Carboxyl Groups
inferredcites →https://doi.org/10.1074/jbc.m703378200openalex-snapshot
Functional Characterization of Premnaspirodiene Oxygenase, a Cytochrome P450 Catalyzing Regio- and Stereo-specific Hydroxylations of Diverse Sesquiterpene Substrates
inferredcites →https://doi.org/10.1074/jbc.m710421200openalex-snapshot
Biosynthesis of the Sesquiterpene Antibiotic Albaflavenone in Streptomyces coelicolor A3(2)
inferredcites →https://doi.org/10.1093/femsle/fnx110openalex-snapshot
Cytochrome P450 enzyme RosC catalyzes a multistep oxidation reaction to form the non-active compound 20-carboxyrosamicin
inferredcites →https://doi.org/10.1093/jb/mvq001openalex-snapshot
Structural diversity of cytochrome P450 enzyme system
inferredcites →https://doi.org/10.1111/j.1365-2958.2004.04090.xopenalex-snapshot
Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tü4055: insights into nitrile formation †
inferredcites →https://doi.org/10.1111/j.1742-4658.2011.08447.xopenalex-snapshot
Investigating conservation of the albaflavenone biosynthetic pathway and CYP170 bifunctionality in streptomycetes
inferredcites →https://doi.org/10.1126/science.1709302openalex-snapshot
Atomic Structure of FKBP-FK506, an Immunophilin-Immunosuppressant Complex
inferredcites →https://doi.org/10.1128/aac.00512-13openalex-snapshot
Post-PKS Tailoring Steps of the Spiramycin Macrolactone Ring in Streptomyces ambofaciens
inferredcites →https://doi.org/10.1128/aac.02092-12openalex-snapshot
Function of Cytochrome P450 Enzymes RosC and RosD in the Biosynthesis of Rosamicin Macrolide Antibiotic Produced by Micromonospora rosaria
inferredcites →https://doi.org/10.1128/aac.06063-11openalex-snapshot
Function of Cytochrome P450 Enzymes MycCI and MycG in Micromonospora griseorubida, a Producer of the Macrolide Antibiotic Mycinamicin
inferredcites →https://doi.org/10.1128/aem.00859-08openalex-snapshot
Tailoring the P450 Monooxygenase Gene for FR-008/Candicidin Biosynthesis
inferredcites →https://doi.org/10.1128/aem.05780-11openalex-snapshot
New Nystatin-Related Antifungal Polyene Macrolides with Altered Polyol Region Generated via Biosynthetic Engineering of Streptomyces noursei
inferredcites →https://doi.org/10.1128/jb.00033-13openalex-snapshot
FK506 Maturation Involves a Cytochrome P450 Protein-Catalyzed Four-Electron C-9 Oxidation in Parallel with a C-31O-Methylation
inferredcites →https://doi.org/10.1128/jb.172.6.3335-3345.1990openalex-snapshot
Genes for two herbicide-inducible cytochromes P-450 from Streptomyces griseolus
inferredcites →https://doi.org/10.1128/jb.177.3.676-687.1995openalex-snapshot
Degradation of the thiocarbamate herbicide EPTC (S-ethyl dipropylcarbamothioate) and biosafening by Rhodococcus sp. strain NI86/21 involve an inducible cytochrome P-450 system and aldehyde dehydrogenase
inferredcites →https://doi.org/10.1128/jb.179.8.2641-2650.1997openalex-snapshot
In vivo and in vitro bioconversion of epsilon-rhodomycinone glycoside to doxorubicin: functions of DauP, DauK, and DoxA
inferredcites →https://doi.org/10.1128/jb.181.1.298-304.1999openalex-snapshot
Purification, Properties, and Characterization of Recombinant Streptomyces sp. Strain C5 DoxA, a Cytochrome P-450 Catalyzing Multiple Steps in Doxorubicin Biosynthesis
inferredcites →https://doi.org/10.1128/jb.181.1.305-318.1999openalex-snapshot
Doxorubicin Overproduction in Streptomyces peucetius : Cloning and Characterization of the dnrU Ketoreductase and dnrV Genes and the doxA Cytochrome P-450 Hydroxylase Gene
inferredcites →https://doi.org/10.4062/biomolther.2018.183openalex-snapshot
StreptomycesCytochrome P450 Enzymes and Their Roles in the Biosynthesis of Macrolide Therapeutic Agents
inferredcites →https://doi.org/10.7164/antibiotics.36.131openalex-snapshot
Biosynthesis of the macrolide antibiotic tylosin. A preferred pathway from tylactone to tylosin.
inferredcites →https://doi.org/10.7164/antibiotics.50.418openalex-snapshot
Chemical and Biological Characterization of Two FK506 Analogs Produced by Targeted Gene Disruption in Streptomyces sp. MA6548.
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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