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Ischemic stroke: experimental models and reality

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/archneur.59.12.1870openalex-snapshot
Nonocclusion and Spontaneous Recanalization Rates in Acute Ischemic Stroke
inferredcites →https://doi.org/10.1002/ana.21549openalex-snapshot
Lacunar stroke is associated with diffuse blood–brain barrier dysfunction
inferredcites →https://doi.org/10.1002/ana.410170513openalex-snapshot
Induction of reproducible brain infarction by photochemically initiated thrombosis
inferredcites →https://doi.org/10.1002/jnr.23836openalex-snapshot
Prospects of modeling poststroke epileptogenesis
inferredcites →https://doi.org/10.1002/mrm.20100openalex-snapshot
Microsphere‐induced embolic stroke: An MRI study
inferredcites →https://doi.org/10.1007/978-1-4939-5620-3openalex-snapshot
Rodent Models of Stroke
inferredcites →https://doi.org/10.1007/s00062-011-0113-2openalex-snapshot
Comparison of Digital Subtraction Angiography, Micro-Computed Tomography Angiography and Magnetic Resonance Angiography in the Assessment of the Cerebrovascular System in Live Mice
inferredcites →https://doi.org/10.1007/s00401-008-0473-0openalex-snapshot
Neuronal plasticity after ischemic preconditioning and TIA-like preconditioning ischemic periods
inferredcites →https://doi.org/10.1007/s10522-013-9465-0openalex-snapshot
Preclinical models of stroke in aged animals with or without comorbidities: role of neuroinflammation
inferredcites →https://doi.org/10.1007/s11011-014-9499-2openalex-snapshot
Improving the translation of animal ischemic stroke studies to humans
inferredcites →https://doi.org/10.1007/s12975-016-0455-9openalex-snapshot
Strain-Related Differences in the Immune Response: Relevance to Human Stroke
inferredcites →https://doi.org/10.1007/s12975-016-0467-5openalex-snapshot
Spontaneous and Therapeutic-Induced Mechanisms of Functional Recovery After Stroke
inferredcites →https://doi.org/10.1007/s13311-012-0115-zopenalex-snapshot
Nonhuman Primate Models of Stroke for Translational Neuroprotection Research
inferredcites →https://doi.org/10.1016/0300-9572(93)90143-eopenalex-snapshot
Ischemia-mediated neuronal injury
inferredcites →https://doi.org/10.1016/b978-0-444-53630-3.00012-9openalex-snapshot
Gender and the injured brain
inferredcites →https://doi.org/10.1016/j.brainres.2003.10.028openalex-snapshot
Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice
inferredcites →https://doi.org/10.1016/j.jchemneu.2003.12.002openalex-snapshot
Cellular distribution of the endothelin system in the human brain
inferredcites →https://doi.org/10.1016/j.jneumeth.2006.01.028openalex-snapshot
A new model of thromboembolic stroke in the posterior circulation of the rat
inferredcites →https://doi.org/10.1016/j.jneumeth.2009.03.017openalex-snapshot
A white matter stroke model in the mouse: Axonal damage, progenitor responses and MRI correlates
inferredcites →https://doi.org/10.1016/j.jneumeth.2010.04.017openalex-snapshot
A novel method for inducing focal ischemia in vitro
inferredcites →https://doi.org/10.1016/j.jneumeth.2014.05.014openalex-snapshot
A reproducible Endothelin-1 model of forelimb motor cortex stroke in the mouse
inferredcites →https://doi.org/10.1016/j.jneumeth.2014.10.004openalex-snapshot
Whole-scale neurobehavioral assessments of photothrombotic ischemia in freely moving mice
inferredcites →https://doi.org/10.1016/j.jocn.2008.04.002openalex-snapshot
Imaging the penumbra – strategies to detect tissue at risk after ischemic stroke
inferredcites →https://doi.org/10.1016/j.jstrokecerebrovasdis.2014.12.024openalex-snapshot
Cryptogenic Stroke: Clinical Consideration of a Heterogeneous Ischemic Subtype
inferredcites →https://doi.org/10.1016/j.mcn.2012.09.004openalex-snapshot
Systemic immune activation shapes stroke outcome
inferredcites →https://doi.org/10.1016/j.neuron.2010.07.002openalex-snapshot
The Science of Stroke: Mechanisms in Search of Treatments
inferredcites →https://doi.org/10.1016/j.neuron.2015.03.021openalex-snapshot
Brains, Genes, and Primates
inferredcites →https://doi.org/10.1016/j.neuropharm.2007.12.004openalex-snapshot
Cerebral ischemia: Models, methods and outcomes
inferredcites →https://doi.org/10.1016/j.pbb.2007.04.015openalex-snapshot
Acute ischemic stroke: Overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia
inferredcites →https://doi.org/10.1016/j.tins.2013.12.001openalex-snapshot
The human side of microglia
inferredcites →https://doi.org/10.1016/s0079-6123(08)63263-xopenalex-snapshot
Chapter 9 NMDA receptors and AMPA/kainate receptors mediate parallel injury in cerebral cortical cultures subjected to oxygen-glucose deprivation
inferredcites →https://doi.org/10.1016/s0140-6736(03)14544-8openalex-snapshot
Stroke
inferredcites →https://doi.org/10.1016/s0140-6736(16)00163-xopenalex-snapshot
Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials
inferredcites →https://doi.org/10.1016/s0165-0270(02)00322-9openalex-snapshot
The macrosphere model
inferredcites →https://doi.org/10.1016/s0300-483x(03)00043-xopenalex-snapshot
Species differences in the structure and function of the immune system
inferredcites →https://doi.org/10.1016/s0306-4522(00)00345-6openalex-snapshot
Endothelin-converting enzymes and endothelin receptor B messenger RNAs are expressed in different neural cell species and these messenger RNAs are coordinately induced in neurons and astrocytes respectively following nerve injury
inferredcites →https://doi.org/10.1023/b:mebr.0000043966.46964.e6openalex-snapshot
Pathophysiology of Stroke: Lessons from Animal Models
inferredcites →https://doi.org/10.1038/255332a0openalex-snapshot
Effect of experimental cerebral infarction in rat brain on catecholamines and behaviour
inferredcites →https://doi.org/10.1038/jcbfm.1981.6openalex-snapshot
Focal Cerebral Ischaemia in the Rat: 1. Description of Technique and Early Neuropathological Consequences following Middle Cerebral Artery Occlusion
inferredcites →https://doi.org/10.1038/jcbfm.1988.88openalex-snapshot
Focal Brain Ischemia in the Rat: Methods for Reproducible Neocortical Infarction Using Tandem Occlusion of the Distal Middle Cerebral and Ipsilateral Common Carotid Arteries
inferredcites →https://doi.org/10.1038/jcbfm.1990.46openalex-snapshot
Contractile Responses to Endothelin in Feline Cortical Vessels in situ
inferredcites →https://doi.org/10.1038/jcbfm.2008.91openalex-snapshot
Do in vivo Experimental Models Reflect Human Cerebral Small Vessel Disease? a Systematic Review
inferredcites →https://doi.org/10.1038/jcbfm.2010.66openalex-snapshot
Different Strokes for Different Folks: The Rich Diversity of Animal Models of Focal Cerebral Ischemia
inferredcites →https://doi.org/10.1038/jcbfm.2011.186openalex-snapshot
The Two Pathophysiologies of Focal Brain Ischemia: Implications for Translational Stroke Research
inferredcites →https://doi.org/10.1038/jcbfm.2012.51openalex-snapshot
International, Multicenter Randomized Preclinical Trials in Translational Stroke Research: It's Time to Act
inferredcites →https://doi.org/10.1038/nn.3426openalex-snapshot
The cortical angiome: an interconnected vascular network with noncolumnar patterns of blood flow
inferredcites →https://doi.org/10.1038/nri3192openalex-snapshot
The storm has cleared: lessons from the CD28 superagonist TGN1412 trial
inferredcites →https://doi.org/10.1038/nri3192-c2openalex-snapshot
Response to 'Storm forecasting: additional lessons from the CD28 superagonist TGN1412 trial'
inferredcites →https://doi.org/10.1038/nrn1765openalex-snapshot
Central nervous system injury-induced immune deficiency syndrome
inferredcites →https://doi.org/10.1038/srep31608openalex-snapshot
Endovascular ischemic stroke models of adult rhesus monkeys: a comparison of two endovascular methods
inferredcites →https://doi.org/10.1056/nejmoa070240openalex-snapshot
NXY-059 for the Treatment of Acute Ischemic Stroke
inferredcites →https://doi.org/10.1073/pnas.1413624111openalex-snapshot
Comparison of the transcriptional landscapes between human and mouse tissues
inferredcites →https://doi.org/10.1089/ars.2013.5669openalex-snapshot
Neurovascular Regulation in the Ischemic Brain
inferredcites →https://doi.org/10.1093/brain/awg040openalex-snapshot
Markers of endothelial dysfunction in lacunar infarction and ischaemic leukoaraiosis
inferredcites →https://doi.org/10.1093/cercor/bhw010openalex-snapshot
Direct Visualization and Mapping of the Spatial Course of Fiber Tracts at Microscopic Resolution in the Human Hippocampus
inferredcites →https://doi.org/10.1097/00004311-199603440-00007openalex-snapshot
Anesthetics and Cerebroprotection
inferredcites →https://doi.org/10.1097/00004647-199804000-00004openalex-snapshot
A Reproducible Model of Middle Cerebral Artery Occlusion in Mice: Hemodynamic, Biochemical, and Magnetic Resonance Imaging
inferredcites →https://doi.org/10.1097/00004647-200012000-00008openalex-snapshot
Involvement of Oxidative Stress and Caspase-3 in Cortical Infarction after Photothrombotic Ischemia in Mice
inferredcites →https://doi.org/10.1097/00004872-198812040-00056openalex-snapshot
A novel peptide vasoconstrictor, endothelin, is produced by vascular endothelium and modulates smooth muscle Ca2+ channels
inferredcites →https://doi.org/10.1097/00005072-198307000-00005openalex-snapshot
Mechanisms of Blood-Brain Barrier Breakdown After Microembolization of the Cat's Brain
inferredcites →https://doi.org/10.1097/00019052-199702000-00010openalex-snapshot
Recovery and repair issues after stroke from the scientific perspective
inferredcites →https://doi.org/10.1097/01.aco.0000245271.84539.4copenalex-snapshot
Brain protection by anesthetic agents
inferredcites →https://doi.org/10.1097/nen.0000000000000124openalex-snapshot
Blood-Brain Barrier Dysfunction and Cerebral Small Vessel Disease (Arteriolosclerosis) in Brains of Older People
inferredcites →https://doi.org/10.1097/wco.0000000000000025openalex-snapshot
The interaction between training and plasticity in the poststroke brain
inferredcites →https://doi.org/10.1111/bph.12775openalex-snapshot
Of mice and men: modelling post‐stroke depression experimentally
inferredcites →https://doi.org/10.1111/j.1365-2990.2011.01170.xopenalex-snapshot
Cerebral small vessel endothelial structural changes predate hypertension in stroke‐prone spontaneously hypertensive rats: a blinded, controlled immunohistochemical study of 5‐ to 21‐week‐old rats
inferredcites →https://doi.org/10.1111/j.1747-4949.2011.00659.xopenalex-snapshot
Is the Spontaneously Hypertensive Stroke Prone Rat a Pertinent Model of Sub Cortical Ischemic Stroke? A Systematic Review
inferredcites →https://doi.org/10.1111/j.1747-4949.2012.00838.xopenalex-snapshot
Etiology of Stroke and Choice of Models
inferredcites →https://doi.org/10.1111/j.1749-6632.2012.06691.xopenalex-snapshot
Pathobiology of injury after stroke: the neurovascular unit and beyond
inferredcites →https://doi.org/10.1111/j.1750-3639.2012.00575.xopenalex-snapshot
Pathology of Lacunar Ischemic Stroke in Humans—A Systematic Review
inferredcites →https://doi.org/10.1117/1.jbo.19.9.096013openalex-snapshot
Induction and imaging of photothrombotic stroke in conscious and freely moving rats
inferredcites →https://doi.org/10.1126/science.1225829openalex-snapshot
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
inferredcites →https://doi.org/10.1126/science.3934754openalex-snapshot
Tissue Plasminogen Activator Reduces Neurological Damage After Cerebral Embolism
inferredcites →https://doi.org/10.1126/science.462179openalex-snapshot
Differential Behavioral and Biochemical Effects of Right and Left Hemispheric Cerebral Infarction in the Rat
inferredcites →https://doi.org/10.1136/jnnp-2012-303645openalex-snapshot
Cognitive impairment after lacunar stroke: systematic review and meta-analysis of incidence, prevalence and comparison with other stroke subtypes
inferredcites →https://doi.org/10.1159/000111499openalex-snapshot
Cellular Immunodepression Preceding Infectious Complications after Acute Ischemic Stroke in Humans
inferredcites →https://doi.org/10.1159/000118039openalex-snapshot
Improving Outcome after Stroke: Overcoming the Translational Roadblock
inferredcites →https://doi.org/10.1159/000350199openalex-snapshot
Stroke-Associated Pneumonia: Major Advances and Obstacles
inferredcites →https://doi.org/10.1159/000357150openalex-snapshot
Multiplicity of Risk Factors in Ischemic Stroke Patients: Relations to Age, Sex, and Subtype - A Study of 2,505 Patients from the Lund Stroke Register
inferredcites →https://doi.org/10.1159/000442997openalex-snapshot
Which Aspects of Stroke Do Animal Models Capture? A Multitracer Micro-PET Study of Focal Ischemia with Endothelin-1
inferredcites →https://doi.org/10.1161/01.hyp.6.6_pt_2.iii81openalex-snapshot
Cerebral vascular bed in hypertension and consequences for the brain.
inferredcites →https://doi.org/10.1161/01.str.0000087790.79851.a8openalex-snapshot
Functional and Histological Evidence for the Protective Effect of NXY-059 in a Primate Model of Stroke When Given 4 Hours After Occlusion
inferredcites →https://doi.org/10.1161/01.str.0000129335.28301.f5openalex-snapshot
Ischemic Stroke Subtypes
inferredcites →https://doi.org/10.1161/01.str.0000142134.37512.a7openalex-snapshot
Complications and Pitfalls in Rat Stroke Models for Middle Cerebral Artery Occlusion
inferredcites →https://doi.org/10.1161/01.str.12.6.723openalex-snapshot
Thresholds in cerebral ischemia - the ischemic penumbra.
inferredcites →https://doi.org/10.1161/01.str.13.4.505openalex-snapshot
An animal model of cerebral infarction. Homologous blood clot emboli in rats.
inferredcites →https://doi.org/10.1161/01.str.16.3.459openalex-snapshot
Cause of cerebral infarction in the carotid territory. Its relation to the size and the location of the infarct and to the underlying vascular lesion.
inferredcites →https://doi.org/10.1161/01.str.17.4.738openalex-snapshot
A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction.
inferredcites →https://doi.org/10.1161/01.str.19.4.498openalex-snapshot
The rat hippocampal slice preparation as an in vitro model of ischemia.
inferredcites →https://doi.org/10.1161/01.str.20.1.84openalex-snapshot
Reversible middle cerebral artery occlusion without craniectomy in rats.
inferredcites →https://doi.org/10.1161/01.str.24.12.2087openalex-snapshot
Anatomic variation of the middle cerebral artery in the Sprague-Dawley rat.
inferredcites →https://doi.org/10.1161/01.str.26.3.430openalex-snapshot
Spontaneous Middle Cerebral Artery Reperfusion in Ischemic Stroke
inferredcites →https://doi.org/10.1161/01.str.26.3.444openalex-snapshot
A Photothrombotic ‘Ring’ Model of Rat Stroke-in-Evolution Displaying Putative Penumbral Inversion
inferredcites →https://doi.org/10.1161/01.str.28.6.1245openalex-snapshot
DNA Scission After Focal Brain Ischemia
inferredcites →https://doi.org/10.1161/01.str.30.11.2464openalex-snapshot
Spontaneous Hyperthermia and its Mechanism in the Intraluminal Suture Middle Cerebral Artery Occlusion Model of Rats
inferredcites →https://doi.org/10.1161/01.str.30.12.2752openalex-snapshot
Recommendations for Standards Regarding Preclinical Neuroprotective and Restorative Drug Development
inferredcites →https://doi.org/10.1161/01.str.31.12.3054openalex-snapshot
A Modified Transorbital Baboon Model of Reperfused Stroke
inferredcites →https://doi.org/10.1161/cir.0000000000000366openalex-snapshot
Executive Summary: Heart Disease and Stroke Statistics—2016 Update
inferredcites →https://doi.org/10.1161/cir.0b013e3182456d46openalex-snapshot
Executive Summary: Heart Disease and Stroke Statistics—2012 Update
inferredcites →https://doi.org/10.1161/circresaha.110.224634openalex-snapshot
Genetic Architecture Underlying Variation in Extent and Remodeling of the Collateral Circulation
inferredcites →https://doi.org/10.1161/strokeaha.107.487520openalex-snapshot
Mouse Model of In Situ Thromboembolic Stroke and Reperfusion
inferredcites →https://doi.org/10.1161/strokeaha.107.496448openalex-snapshot
Blocking of Platelets or Intrinsic Coagulation Pathway–Driven Thrombosis Does Not Prevent Cerebral Infarctions Induced by Photothrombosis
inferredcites →https://doi.org/10.1161/strokeaha.108.521740openalex-snapshot
Ultrafast High-Resolution In Vivo Volume-CTA of Mice Cerebral Vessels
inferredcites →https://doi.org/10.1161/strokeaha.108.525386openalex-snapshot
Good Laboratory Practice
inferredcites →https://doi.org/10.1161/strokeaha.108.528430openalex-snapshot
Potential Animal Models of Lacunar Stroke
inferredcites →https://doi.org/10.1161/strokeaha.108.541128openalex-snapshot
Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations
inferredcites →https://doi.org/10.1161/strokeaha.111.622159openalex-snapshot
Successful Regeneration After Experimental Stroke by Granulocyte-Colony Stimulating Factor Is Not Further Enhanced by Constraint-Induced Movement Therapy Either in Concurrent or in Sequential Combination Therapy
inferredcites →https://doi.org/10.1161/strokeaha.111.648725openalex-snapshot
Prediction of Cardioembolic, Arterial, and Lacunar Causes of Cryptogenic Stroke by Gene Expression and Infarct Location
inferredcites →https://doi.org/10.1161/strokeaha.113.004075openalex-snapshot
Found in Translation
inferredcites →https://doi.org/10.1161/strokeaha.114.005639openalex-snapshot
Modeling Immunity and Inflammation in Stroke
inferredcites →https://doi.org/10.1161/strokeaha.115.011932openalex-snapshot
Modeling Ischemic Stroke In Vitro: Status Quo and Future Perspectives
inferredcites →https://doi.org/10.1161/strokeaha.116.013244openalex-snapshot
Thomas Willis Lecture
inferredcites →https://doi.org/10.1161/strokeaha.116.014356openalex-snapshot
Remote Lower White Matter Integrity Increases the Risk of Long-Term Cognitive Impairment After Ischemic Stroke in Young Adults
inferredcites →https://doi.org/10.1176/appi.ajp.2015.15030363openalex-snapshot
Post-Stroke Depression: A Review
inferredcites →https://doi.org/10.1177/0271678x16636890openalex-snapshot
Gut microbiota impact on stroke outcome: Fad or fact?
inferredcites →https://doi.org/10.1177/0271678x16656199openalex-snapshot
Differential subnetwork of chemokines/cytokines in human, mouse, and rat brain cells after oxygen–glucose deprivation
inferredcites →https://doi.org/10.1177/0271678x16670922openalex-snapshot
Stroke-induced blood–brain barrier breakdown along the vascular tree – No preferential affection of arteries in different animal models and in humans
inferredcites →https://doi.org/10.1177/1545968312440745openalex-snapshot
Getting Neurorehabilitation Right
inferredcites →https://doi.org/10.1177/1747493016641968openalex-snapshot
Post-stroke depression, obstructive sleep apnea, and cognitive impairment: Rationale for, and barriers to, routine screening
inferredcites →https://doi.org/10.1179/174313209x382278openalex-snapshot
The plasticity of posterior communicating artery influences on the outcome of white matter injury induced by chronic cerebral hypoperfusion in rats
inferredcites →https://doi.org/10.1179/1743132814y.0000000358openalex-snapshot
Rodent models of ischemic stroke lack translational relevance… are baboon models the answer?
inferredcites →https://doi.org/10.1186/1471-2377-6-22openalex-snapshot
Are the distributions of variations of circle of Willis different in different populations? – Results of an anatomical study and review of literature
inferredcites →https://doi.org/10.1186/s40478-016-0371-yopenalex-snapshot
Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue
inferredcites →https://doi.org/10.1186/scrt379openalex-snapshot
Neurovascular unit on a chip: implications for translational applications
inferredcites →https://doi.org/10.1253/jcj.27.282openalex-snapshot
Development of a Strain of Spontaneously Hypertensive Rats
inferredcites →https://doi.org/10.1371/journal.pbio.1000412openalex-snapshot
Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
inferredcites →https://doi.org/10.1371/journal.pone.0022351openalex-snapshot
Dibucaine Mitigates Spreading Depolarization in Human Neocortical Slices and Prevents Acute Dendritic Injury in the Ischemic Rodent Neocortex
inferredcites →https://doi.org/10.1371/journal.pone.0116704openalex-snapshot
Effects of Vendor and Genetic Background on the Composition of the Fecal Microbiota of Inbred Mice
inferredcites →https://doi.org/10.1371/journal.pone.0127355openalex-snapshot
Selection of Genes Associated with Variations in the Circle of Willis in Gerbils Using Suppression Subtractive Hybridization
inferredcites →https://doi.org/10.1371/journal.pone.0146679openalex-snapshot
Functional Improvement after Photothrombotic Stroke in Rats Is Associated with Different Patterns of Dendritic Plasticity after G-CSF Treatment and G-CSF Treatment Combined with Concomitant or Sequential Constraint-Induced Movement Therapy
inferredcites →https://doi.org/10.1523/jneurosci.13-08-03510.1993openalex-snapshot
Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury
inferredcites →https://doi.org/10.1602/neurorx.2.3.396openalex-snapshot
Rodent models of focal stroke: Size, mechanism, and purpose
inferredcites →https://doi.org/10.2147/dddt.s56071openalex-snapshot
Animal models of ischemic stroke and their application in clinical research
inferredcites →https://doi.org/10.2165/00044011-200424050-00001openalex-snapshot
Risk Reduction Strategies in Ischaemic Stroke
inferredcites →https://doi.org/10.3389/fnana.2016.00040openalex-snapshot
Estimating Fiber Orientation Distribution Functions in 3D-Polarized Light Imaging
inferredcites →https://doi.org/10.3389/fneur.2015.00008openalex-snapshot
Data Science of Stroke Imaging and Enlightenment of the Penumbra
inferredcites →https://doi.org/10.3389/fneur.2015.00172openalex-snapshot
Considerations for the Optimization of Induced White Matter Injury Preclinical Models
inferredcites →https://doi.org/10.3389/fninf.2011.00034openalex-snapshot
High-Resolution Fiber Tract Reconstruction in the Human Brain by Means of Three-Dimensional Polarized Light Imaging
inferredcites →https://doi.org/10.3978/j.issn.2305-5839.2015.04.02openalex-snapshot
The macrosphere model-an embolic stroke model for studying the pathophysiology of focal cerebral ischemia in a translational approach.
inferredcites →https://doi.org/10.3995/jstroke.8.1openalex-snapshot
Experimental studies of ischemic brain edema
inferredcites →https://doi.org/10.4049/jimmunol.1301758openalex-snapshot
Epigenetic Silencing of the Human NOS2 Gene: Rethinking the Role of Nitric Oxide in Human Macrophage Inflammatory Responses
inferredcites →https://doi.org/10.4103/0976-500x.72351openalex-snapshot
Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research
inferredcites →https://doi.org/10.4103/1673-5374.165208openalex-snapshot
Neuroinflammation and comorbidities are frequently ignored factors in CNS pathology

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3961041openalex-extracted
Genetic Deletion of Nt5e Does Not Affect Stroke Size and Inflammation Profile in the Transient Middle Cerebral Artery Occlusion Model of Murine Stroke
inferred← citeshttps://doi.org/10.1002/adfm.201906283openalex-snapshot
Advanced Functional Materials and Cell‐Based Therapies for the Treatment of Ischemic Stroke and Postischemic Stroke Effects
inferred← citeshttps://doi.org/10.1002/adhm.201700818openalex-snapshot
Cell‐Based Drug Delivery and Use of Nano‐and Microcarriers for Cell Functionalization
inferred← citeshttps://doi.org/10.1002/advs.202205752openalex-snapshot
3D In Vitro Blood‐Brain‐Barrier Model for Investigating Barrier Insults
inferred← citeshttps://doi.org/10.1002/ame2.12166openalex-snapshot
Preclinical animal studies in ischemic stroke: Challenges and some solutions
inferred← citeshttps://doi.org/10.1002/ana.25665openalex-snapshot
Local Leukocyte Invasion during Hyperacute Human Ischemic Stroke
inferred← citeshttps://doi.org/10.1002/cmdc.202400975openalex-snapshot
Signaling Pathways and Promising Small‐Molecule Therapeutic Agents for Ischemic Stroke
inferred← citeshttps://doi.org/10.1002/cphy.c210015openalex-snapshot
Endothelial Cells and the Cerebral Circulation
inferred← citeshttps://doi.org/10.1002/glia.24501openalex-snapshot
Role of microglia in stroke
inferred← citeshttps://doi.org/10.1002/glia.70215openalex-snapshot
LILRB4 Attenuates Ischemic Brain Injury by Inhibiting Microglial Necroptosis via a RIPK3 ‐Dependent Mechanism
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2022.tb00220.xopenalex-snapshot
Endothelial Cells and the Cerebral Circulation
inferred← citeshttps://doi.org/10.1002/jbt.23070openalex-snapshot
Silencing ATF4 inhibits JMJD3‐dependent JUNB/ETS1 axis and mitigates cerebral ischemic injury
inferred← citeshttps://doi.org/10.1002/jcp.30768openalex-snapshot
Glutamate–aspartate transporter 1 attenuates oxygen–glucose deprivation‐induced injury by promoting glutamate metabolism in primary cortical neurons
inferred← citeshttps://doi.org/10.1002/nbm.4703openalex-snapshot
Perfusion system for studying dynamic metabolomics in rat brain slices exposed to oxygen–glucose deprivation using proton and phosphorus nuclear magnetic resonance
inferred← citeshttps://doi.org/10.1002/nep3.62openalex-snapshot
Rodent ischemic stroke models and their relevance in preclinical research
inferred← citeshttps://doi.org/10.1002/path.4999openalex-snapshot
Dissociation of nNOS from PSD‐95 promotes functional recovery after cerebral ischaemia in mice through reducing excessive tonic GABA release from reactive astrocytes
inferred← citeshttps://doi.org/10.1002/prp2.448openalex-snapshot
Efficacy of SMTP ‐7, a small‐molecule anti‐inflammatory thrombolytic, in embolic stroke in monkeys
inferred← citeshttps://doi.org/10.1002/sctm.20-0268openalex-snapshot
Neuroprotective effects of human amniotic fluid stem cells-derived secretome in an ischemia/reperfusion model
inferred← citeshttps://doi.org/10.1007/978-1-0716-2926-0_1openalex-snapshot
Rodent Stroke Models to Study Functional Recovery and Neural Repair
inferred← citeshttps://doi.org/10.1007/978-1-4939-9682-7_11openalex-snapshot
Glutamate Receptor Peptides as Potential Neurovascular Biomarkers of Acute Stroke
inferred← citeshttps://doi.org/10.1007/978-1-4939-9682-7_4openalex-snapshot
Neuroplasticity Biomarkers in Experimental Stroke Recovery
inferred← citeshttps://doi.org/10.1007/978-1-4939-9810-4_4openalex-snapshot
Modeling Traumatic Brain Injuries, Aneurysms, and Strokes
inferred← citeshttps://doi.org/10.1007/978-3-030-81400-7_8openalex-snapshot
Therapeutic Approaches for Stroke: A Biomaterials Perspective
inferred← citeshttps://doi.org/10.1007/978-3-031-13924-6_9openalex-snapshot
Cerebrovascular Disease
inferred← citeshttps://doi.org/10.1007/978-3-031-25191-7_8openalex-snapshot
Three-Dimensional Model of Cerebral Artery Based on Medical Image
inferred← citeshttps://doi.org/10.1007/978-981-10-5804-2_1openalex-snapshot
Stroke Therapy Development Successes: Research Guidelines and Embolic Stroke Models for Monotherapy and Adjuvant Therapy Development
inferred← citeshttps://doi.org/10.1007/978-981-13-7142-4_2openalex-snapshot
Animal Models of Ischemic Stroke
inferred← citeshttps://doi.org/10.1007/978-981-16-0987-9_32openalex-snapshot
Surgical Models of Laboratory Animals
inferred← citeshttps://doi.org/10.1007/978-981-33-6679-4_4openalex-snapshot
A Non-human Primate Model for Cerebral Stroke
inferred← citeshttps://doi.org/10.1007/978-981-33-6679-4_8openalex-snapshot
Photothrombotic Stroke Model
inferred← citeshttps://doi.org/10.1007/978-981-95-0125-0_3openalex-snapshot
Natural Compounds and Their Mechanism of Action: Therapeutic Targets of Neuroprotection and Neurorestoration in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1007/978-981-97-1335-6_17openalex-snapshot
Diagnostic Genes Identification and Molecular Classification Patterns Based on Oxidative Stress-Related Genes in Ischemic Stroke
inferred← citeshttps://doi.org/10.1007/978-981-97-6818-9_3openalex-snapshot
Experimental Models of Stroke: Seeing the Unseen
inferred← citeshttps://doi.org/10.1007/978-981-99-9510-3_9openalex-snapshot
Deciphering the Role of Nanomedicines for the Treatment of Ischemic Stroke
inferred← citeshttps://doi.org/10.1007/s00018-021-03897-5openalex-snapshot
The role of leukocytes in acute ischemic stroke-related thrombosis: a notable but neglected topic
inferred← citeshttps://doi.org/10.1007/s00044-022-02875-1openalex-snapshot
Design, synthesis and biological evaluation of indoline derivatives as multifunctional agents for the treatment of ischemic stroke
inferred← citeshttps://doi.org/10.1007/s00062-020-00951-wopenalex-snapshot
55. Jahrestagung der Deutschen Gesellschaft für Neuroradiologie e.V.
inferred← citeshttps://doi.org/10.1007/s00210-020-02005-xopenalex-snapshot
Noscapine alleviates cerebral damage in ischemia-reperfusion injury in rats
inferred← citeshttps://doi.org/10.1007/s00210-025-04288-4openalex-snapshot
Innovative approaches for the treatment of stroke: a recent update
inferred← citeshttps://doi.org/10.1007/s00216-020-02987-wopenalex-snapshot
CpG preconditioning reduces accumulation of lysophosphatidylcholine in ischemic brain tissue after middle cerebral artery occlusion
inferred← citeshttps://doi.org/10.1007/s00216-025-06245-9openalex-snapshot
Engineering localized injury: a 3D microfluidic platform approach for ex vivo tissue interrogation
inferred← citeshttps://doi.org/10.1007/s00281-023-00987-3openalex-snapshot
The role of the ATP-adenosine axis in ischemic stroke
inferred← citeshttps://doi.org/10.1007/s00330-020-07260-3openalex-snapshot
Endovascular stroke treatment using balloon guide catheters may reduce penumbral tissue damage and improve long-term outcome
inferred← citeshttps://doi.org/10.1007/s00395-022-00961-4openalex-snapshot
Molecular imaging of the brain–heart axis provides insights into cardiac dysfunction after cerebral ischemia
inferred← citeshttps://doi.org/10.1007/s00401-021-02384-2openalex-snapshot
Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function
inferred← citeshttps://doi.org/10.1007/s00406-023-01685-9openalex-snapshot
The atypical antidepressant tianeptine confers neuroprotection against oxygen–glucose deprivation
inferred← citeshttps://doi.org/10.1007/s00709-019-01439-2openalex-snapshot
Ischemic stroke and mitochondria: mechanisms and targets
inferred← citeshttps://doi.org/10.1007/s10495-019-01556-6openalex-snapshot
Apoptosis regulation in the penumbra after ischemic stroke: expression of pro- and antiapoptotic proteins
inferred← citeshttps://doi.org/10.1007/s10517-023-05710-8openalex-snapshot
A Canine Surgical Model of Stroke by Minimally Invasive Occlusion of the Proximal Middle Cerebral Artery
inferred← citeshttps://doi.org/10.1007/s10517-024-06264-zopenalex-snapshot
Protective Effect of Protocatechuic Aldehyde on Cerebral Ischemia/Reperfusion Injury in Rats through Blood—Brain Barrier Protection
inferred← citeshttps://doi.org/10.1007/s10517-026-06700-2openalex-snapshot
Spastic Hypertonia Following Middle Cerebral Artery Occlusion in Rats: Assessment of Behavioral, Electrophysiological, and Morphological Parameters in Dynamics
inferred← citeshttps://doi.org/10.1007/s10571-020-00985-1openalex-snapshot
Hemorrhagic Transformation After Tissue Plasminogen Activator Treatment in Acute Ischemic Stroke
inferred← citeshttps://doi.org/10.1007/s10571-022-01247-yopenalex-snapshot
Oxygen–Glucose Deprivation Decreases the Motility and Length of Axonal Mitochondria in Cultured Dorsal Root Ganglion Cells of Rats
inferred← citeshttps://doi.org/10.1007/s10571-023-01437-2openalex-snapshot
Drivers of Chronic Pathology Following Ischemic Stroke: A Descriptive Review
inferred← citeshttps://doi.org/10.1007/s10571-026-01714-wopenalex-snapshot
Integrative Analysis Identifies PANoptosis-Associated Molecular Patterns and Immune Alterations in Rat Cerebral Ischemic-Reperfusion Injury
inferred← citeshttps://doi.org/10.1007/s11011-021-00792-7openalex-snapshot
Long non-coding RNA Gm11974 aggravates oxygen–glucose deprivation-induced injury via miR-122-5p/SEMA3A axis in ischaemic stroke
inferred← citeshttps://doi.org/10.1007/s11011-021-00881-7openalex-snapshot
LncRNA CEBPA-AS1 knockdown prevents neuronal apoptosis against oxygen glucose deprivation/reoxygenation by regulating the miR-455/GPER1 axis
inferred← citeshttps://doi.org/10.1007/s11011-022-01011-7openalex-snapshot
Metabolomics of ischemic stroke: insights into risk prediction and mechanisms
inferred← citeshttps://doi.org/10.1007/s11011-023-01167-wopenalex-snapshot
α7 nicotinic acetylcholine receptor agonist improved brain injury and impaired glucose metabolism in a rat model of ischemic stroke
inferred← citeshttps://doi.org/10.1007/s11062-026-10035-zopenalex-snapshot
Advanced machine learning-based differentiation of acute ischemic and hemorrhagic stroke
inferred← citeshttps://doi.org/10.1007/s11064-020-03083-2openalex-snapshot
Guanosine Neuroprotective Action in Hippocampal Slices Subjected to Oxygen and Glucose Deprivation Restores ATP Levels, Lactate Release and Glutamate Uptake Impairment: Involvement of Nitric Oxide
inferred← citeshttps://doi.org/10.1007/s11626-024-00986-0openalex-snapshot
MiR-146a-5p downregulated TRAF6/NF-κB p65 pathway to attenuate the injury of HT-22 cells induced by oxygen–glucose deprivation/reoxygenation
inferred← citeshttps://doi.org/10.1007/s12010-023-04802-5openalex-snapshot
MiR-30c-5p-Targeted Regulation of GNAI2 Improves Neural Function Injury and Inflammation in Cerebral Ischemia-Reperfusion Injury
inferred← citeshttps://doi.org/10.1007/s12015-021-10178-yopenalex-snapshot
Bone Marrow Mesenchymal Stem Cells Exert Protective Effects After Ischemic Stroke Through Upregulation of Glutathione
inferred← citeshttps://doi.org/10.1007/s12017-025-08852-2openalex-snapshot
Unraveling the Role of NeuroD2 in Ischemic Pathophysiology: Insight into Neuroprotection Mechanisms Associated with AKT Survival Kinase
inferred← citeshttps://doi.org/10.1007/s12031-018-1063-9openalex-snapshot
Levo-tetrahydropalmatine Attenuates Neuron Apoptosis Induced by Cerebral Ischemia–Reperfusion Injury: Involvement of c-Abl Activation
inferred← citeshttps://doi.org/10.1007/s12031-024-02300-9openalex-snapshot
α7-Nicotinic Acetylcholine Receptor Activation Modulates BV2 Microglial Plasticity via miR-21/TNF-α/NFκB in Oxygen–Glucose Deprivation/Reoxygenation
inferred← citeshttps://doi.org/10.1007/s12035-021-02539-yopenalex-snapshot
Long Non-coding RNA PVT1 Inhibits miR-30c-5p to Upregulate Rock2 to Modulate Cerebral Ischemia/Reperfusion Injury Through MAPK Signaling Pathway Activation
inferred← citeshttps://doi.org/10.1007/s12035-021-02594-5openalex-snapshot
Differential Expression and Distinct Roles of Proteinase-Activated Receptor 2 in Microglia and Neurons in Neonatal Mouse Brain After Hypoxia-Ischemic Injury
inferred← citeshttps://doi.org/10.1007/s12035-021-02648-8openalex-snapshot
The Long Non-coding RNA SNHG12 Functions as a Competing Endogenous RNA to Modulate the Progression of Cerebral Ischemia/Reperfusion Injury
inferred← citeshttps://doi.org/10.1007/s12035-022-03200-yopenalex-snapshot
An Updated Review of Mitochondrial Transplantation as a Potential Therapeutic Strategy Against Cerebral Ischemia and Cerebral Ischemia/Reperfusion Injury
inferred← citeshttps://doi.org/10.1007/s12035-023-03675-3openalex-snapshot
Hsa-miR-877-5p Expression in Acute Ischemic Stroke Based on Bioinformatics Analysis and Clinical Validation
inferred← citeshttps://doi.org/10.1007/s12640-020-00274-1openalex-snapshot
Neutrophil Counts to High-Density Lipoprotein Cholesterol Ratio: a Potential Predictor of Prognosis in Acute Ischemic Stroke Patients After Intravenous Thrombolysis
inferred← citeshttps://doi.org/10.1007/s12640-021-00340-2openalex-snapshot
The Protective Effects of Apremilast Against Oxygen–Glucose Deprivation/Reperfusion (OGD/R)-Induced Inflammation and Apoptosis in Astroglia Mediated by CREB/BDNF
inferred← citeshttps://doi.org/10.1007/s12975-017-0593-8openalex-snapshot
Photothrombotic Stroke as a Model of Ischemic Stroke
inferred← citeshttps://doi.org/10.1007/s12975-018-0615-1openalex-snapshot
Focal Ischaemic Infarcts Expand Faster in Cerebellar Cortex than Cerebral Cortex in a Mouse Photothrombotic Stroke Model
inferred← citeshttps://doi.org/10.1007/s12975-019-00707-wopenalex-snapshot
Therapeutic Role of a Cysteine Precursor, OTC, in Ischemic Stroke Is Mediated by Improved Proteostasis in Mice
inferred← citeshttps://doi.org/10.1007/s12975-020-00799-9openalex-snapshot
Relation of Retinal Oxygen Measures to Electrophysiology and Survival Indicators after Permanent, Incomplete Ischemia in Rats
inferred← citeshttps://doi.org/10.1007/s12975-020-00800-5openalex-snapshot
Perlecan Domain-V Enhances Neurogenic Brain Repair After Stroke in Mice
inferred← citeshttps://doi.org/10.1007/s12975-020-00802-3openalex-snapshot
Lesion Size- and Location-Dependent Recruitment of Contralesional Thalamus and Motor Cortex Facilitates Recovery after Stroke in Mice
inferred← citeshttps://doi.org/10.1007/s12975-021-00915-3openalex-snapshot
Extracellular Vesicle Application as a Novel Therapeutic Strategy for Ischemic Stroke
inferred← citeshttps://doi.org/10.1007/s12975-021-00938-wopenalex-snapshot
Platelet Activation and Chemokine Release Are Related to Local Neutrophil-Dominant Inflammation During Hyperacute Human Stroke
inferred← citeshttps://doi.org/10.1007/s12975-022-01022-7openalex-snapshot
Intravital Imaging Reveals the Ameliorating Effect of Colchicine in a Photothrombotic Stroke Model via Inhibition of Neutrophil Recruitment
inferred← citeshttps://doi.org/10.1007/s12975-022-01082-9openalex-snapshot
Translating Animal Models of Ischemic Stroke to the Human Condition
inferred← citeshttps://doi.org/10.1007/s12975-022-01118-0openalex-snapshot
ATG5 Knockdown Attenuates Ischemia‒Reperfusion Injury by Reducing Excessive Autophagy-Induced Ferroptosis
inferred← citeshttps://doi.org/10.1007/s12975-025-01365-xopenalex-snapshot
Gamma-Benzylidene Digoxin Derivative Attenuates Neurotoxicity Response in a Murine Stroke Model
inferred← citeshttps://doi.org/10.1007/s12975-025-01401-wopenalex-snapshot
Recent Advances in Mitochondrial Transplantation for Ischemic Stroke: A Review of in Vitro and in Vivo Studies
inferred← citeshttps://doi.org/10.1007/s13311-017-0586-zopenalex-snapshot
Endovascular Ischemic Stroke Models in Nonhuman Primates
inferred← citeshttps://doi.org/10.1007/s13311-022-01203-0openalex-snapshot
Ceruletide and Alpha-1 Antitrypsin as a Novel Combination Therapy for Ischemic Stroke
inferred← citeshttps://doi.org/10.1007/s13534-019-00118-8openalex-snapshot
Optical coherence tomography angiography in preclinical neuroimaging
inferred← citeshttps://doi.org/10.1007/s43450-021-00199-6openalex-snapshot
Neuroprotective Effects of Cannabidiol Under Cerebral Ischemic Conditions
inferred← citeshttps://doi.org/10.1007/s44164-023-00046-zopenalex-snapshot
Cortical Spheroid Model for Studying the Effects of Ischemic Brain Injury
inferred← citeshttps://doi.org/10.1016/b978-0-12-815238-6.00024-9openalex-snapshot
DHA-Enriched Formulations as a Promising Strategy for the Treatment of Hypoxic/Ischemic Brain Injury
inferred← citeshttps://doi.org/10.1016/b978-0-12-815305-5.00009-9openalex-snapshot
Transcranial photobiomodulation for stroke in animal models
inferred← citeshttps://doi.org/10.1016/b978-0-12-815305-5.00010-5openalex-snapshot
Photobiomodulation in photothrombotic stroke
inferred← citeshttps://doi.org/10.1016/b978-0-12-815318-5.00017-0openalex-snapshot
WNK-SPAK/OSR1-CCC signaling in ischemic brain damage
inferred← citeshttps://doi.org/10.1016/b978-0-323-29544-4.00004-9openalex-snapshot
Histopathology of Brain Tissue Response to Stroke and Injury
inferred← citeshttps://doi.org/10.1016/b978-0-323-69424-7.00004-1openalex-snapshot
Histopathology of Brain Tissue Response to Stroke and Injury
inferred← citeshttps://doi.org/10.1016/b978-0-323-89833-1.00052-5openalex-snapshot
Intraluminal filament induced middle cerebral artery occlusion model of transient focal cerebral ischemia in rats
inferred← citeshttps://doi.org/10.1016/b978-0-443-23763-8.00062-2openalex-snapshot
Neuroprotective efficacy of melatonin in the pathophysiology of neurodegenerative disorders
inferred← citeshttps://doi.org/10.1016/bs.irn.2024.04.012openalex-snapshot
Cannabidiol in experimental cerebral ischemia
inferred← citeshttps://doi.org/10.1016/j.acthis.2020.151573openalex-snapshot
Structural and chemical changes in glial cells in the rat neocortex induced by constant occlusion of the middle cerebral artery
inferred← citeshttps://doi.org/10.1016/j.ajpath.2021.02.023openalex-snapshot
Endothelial Control of Cerebral Blood Flow
inferred← citeshttps://doi.org/10.1016/j.ajpath.2022.07.008openalex-snapshot
Platelet Endothelial Cell Adhesion Molecule (PECAM/CD31) Blockade Modulates Neutrophil Recruitment Patterns and Reduces Infarct Size in Experimental Ischemic Stroke
inferred← citeshttps://doi.org/10.1016/j.amjms.2021.01.028openalex-snapshot
Clinical Risk Factors Associated with Ambulatory Outcome in Acute Ischemic Stroke Patient Smokers Treated with Thrombolytic Therapy
inferred← citeshttps://doi.org/10.1016/j.arr.2023.102022openalex-snapshot
Age-related pathophysiological alterations in molecular stress markers and key modulators of hypoxia
inferred← citeshttps://doi.org/10.1016/j.arr.2024.102469openalex-snapshot
Stroke studies in large animals: Prospects of mitochondrial transplantation and enhancing efficiency using hydrogels and nanoparticle-assisted delivery
inferred← citeshttps://doi.org/10.1016/j.bbadis.2018.09.012openalex-snapshot
Current advances in ischemic stroke research and therapies
inferred← citeshttps://doi.org/10.1016/j.bbi.2019.04.009openalex-snapshot
Glatiramer acetate reduces infarct volume in diabetic mice with cerebral ischemia and prevents long-term memory loss
inferred← citeshttps://doi.org/10.1016/j.bbi.2020.09.025openalex-snapshot
Filling the gaps on stroke research: Focus on inflammation and immunity
inferred← citeshttps://doi.org/10.1016/j.bbr.2020.113089openalex-snapshot
Hippocampal silent infarct leads to subtle cognitive decline that is associated with inflammation and gliosis at twenty-four hours after injury in a rat model
inferred← citeshttps://doi.org/10.1016/j.bbr.2023.114589openalex-snapshot
Long-term behavioural alterations in mice following transient cerebral ischemia
inferred← citeshttps://doi.org/10.1016/j.bbrc.2026.154606openalex-snapshot
Galectin-3 accelerates the progression of cerebral infarction by regulating the ERK/ROS/BRD4-mediated P2X7R/MerTK balance in microglia
inferred← citeshttps://doi.org/10.1016/j.bioadv.2026.214712openalex-snapshot
An antagomiR-loaded β-peptide hydrogel promotes functional recovery in mice post-ischaemic stroke
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2018.05.009openalex-snapshot
Glycosaminoglycan-based hybrid hydrogel encapsulated with polyelectrolyte complex nanoparticles for endogenous stem cell regulation in central nervous system regeneration
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2025.123379openalex-snapshot
Gadolinium-ceria hybrid system enables synergistic alleviation of oxidative stress and metabolic thrombo-inflammation for efficient ischemic stroke treatment
inferred← citeshttps://doi.org/10.1016/j.biopha.2019.109452openalex-snapshot
Neuroprotective effects of irisin against cerebral ischemia/ reperfusion injury via Notch signaling pathway
inferred← citeshttps://doi.org/10.1016/j.biopha.2019.109786openalex-snapshot
Ischemic postconditioning exerts neuroprotective effect through negatively regulating PI3K/Akt2 signaling pathway by microRNA-124
inferred← citeshttps://doi.org/10.1016/j.biopha.2020.110151openalex-snapshot
Cepharanthine attenuates cerebral ischemia/reperfusion injury by reducing NLRP3 inflammasome-induced inflammation and oxidative stress via inhibiting 12/15-LOX signaling
inferred← citeshttps://doi.org/10.1016/j.biopha.2020.110213openalex-snapshot
Shuxuening injection facilitates neurofunctional recovery via down-regulation of G-CSF-mediated granulocyte adhesion and diapedesis pathway in a subacute stroke mouse model
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.112719openalex-snapshot
Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs
inferred← citeshttps://doi.org/10.1016/j.bmcl.2024.129983openalex-snapshot
Identification of 3-methyl-1-(3-methylpyridin-2-yl)-1H-pyrazol-5-ol as promising neuroprotective agent
inferred← citeshttps://doi.org/10.1016/j.brain.2024.100090openalex-snapshot
A review of brain injury at multiple time scales and its clinicopathological correlation through in silico modeling
inferred← citeshttps://doi.org/10.1016/j.brainres.2018.01.019openalex-snapshot
Akt activation improves microregional oxygen supply/consumption balance after cerebral ischemia-reperfusion
inferred← citeshttps://doi.org/10.1016/j.brainres.2019.146488openalex-snapshot
Continuous theta burst stimulation provides neuroprotection by accelerating local cerebral blood flow and inhibiting inflammation in a mouse model of acute ischemic stroke
inferred← citeshttps://doi.org/10.1016/j.brainres.2023.148247openalex-snapshot
Tongqiao Huoxue decoction alleviates neurological impairment following ischemic stroke via the PTGS2/NF-kappa B axis
inferred← citeshttps://doi.org/10.1016/j.brainres.2024.149296openalex-snapshot
Electroacupuncture extends the time window of thrombolytic therapy in rats by reducing disruptions of blood–brain barrier and inhibiting GSDMD-mediated pyroptosis
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2022.07.022openalex-snapshot
Preconditioning exercise reduces hippocampal neuronal damage via increasing Klotho expression in ischemic rats
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2024.110890openalex-snapshot
IL-17A deficiency alleviates cerebral ischemia-reperfusion injury via activating ERK/MAPK pathway in hippocampal CA1 region
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2024.111029openalex-snapshot
Thymol improves ischemic brain injury by inhibiting microglia-mediated neuroinflammation
inferred← citeshttps://doi.org/10.1016/j.cbi.2020.108946openalex-snapshot
Trigonelline protects hippocampal neurons from oxygen-glucose deprivation-induced injury through activating the PI3K/Akt pathway
inferred← citeshttps://doi.org/10.1016/j.cclet.2020.02.031openalex-snapshot
Design and synthesis of the ring-opened derivative of 3-n-butylphthalide-ferulic acid-glucose trihybrids as potential anti-ischemic agents
inferred← citeshttps://doi.org/10.1016/j.cclet.2023.109149openalex-snapshot
Advanced nano drug delivery systems for neuroprotection against ischemic stroke
inferred← citeshttps://doi.org/10.1016/j.cej.2026.176831openalex-snapshot
A vascular-on-a-chip system recapitulates endothelial injury following ischemic reperfusion
inferred← citeshttps://doi.org/10.1016/j.celbio.2025.100016openalex-snapshot
Mitochondria in brain diseases: Bridging structural-mechanistic insights into precision-targeted therapies
inferred← citeshttps://doi.org/10.1016/j.clinsp.2023.100199openalex-snapshot
Abnormal expression of miRNA-122 in cerebral infarction and related mechanism of regulating vascular endothelial cell proliferation and apoptosis by targeting CCNG1
inferred← citeshttps://doi.org/10.1016/j.crmeth.2022.100183openalex-snapshot
A versatile toolbox for studying cortical physiology in primates
inferred← citeshttps://doi.org/10.1016/j.ebiom.2024.105095openalex-snapshot
MMP-9 release into collateral blood vessels before endovascular thrombectomy to assess the risk of major intracerebral haemorrhages and poor outcome for acute ischaemic stroke: a proof-of-concept study
inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.111695openalex-snapshot
Design, synthesis and biological evaluation of cinnamic acid derivatives with synergetic neuroprotection and angiogenesis effect
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116542openalex-snapshot
Discovery of orally bioavailable phenyltetrazolium derivatives for the acute treatment and the secondary prevention of ischemic stroke
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116907openalex-snapshot
Design, synthesis, and biological evaluation of novel iNOS inhibitors as potent neuroprotective agents for ischemic stroke
inferred← citeshttps://doi.org/10.1016/j.ejphar.2017.07.041openalex-snapshot
Baicalin attenuates in vivo and in vitro hyperglycemia-exacerbated ischemia/reperfusion injury by regulating mitochondrial function in a manner dependent on AMPK
inferred← citeshttps://doi.org/10.1016/j.ejphar.2020.173292openalex-snapshot
Ponatinib-induced ischemic stroke in larval zebrafish for drug screening
inferred← citeshttps://doi.org/10.1016/j.ejphar.2022.174987openalex-snapshot
A novel phosphodiesterase 9A inhibitor LW33 protects against ischemic stroke through the cGMP/PKG/CREB pathway
inferred← citeshttps://doi.org/10.1016/j.ejphar.2023.176228openalex-snapshot
GPR124 induces NLRP3 inflammasome-mediated pyroptosis in endothelial cells during ischemic injury
inferred← citeshttps://doi.org/10.1016/j.ejphar.2024.176512openalex-snapshot
Cytisine–N-methylene-(5,7,4’-trihydroxy)- isoflavone ameliorates ischemic stroke-induced brain injury in mouse by regulating the oxidative stress and BDNF-Trkb/Akt pathway
inferred← citeshttps://doi.org/10.1016/j.ejphar.2026.178813openalex-snapshot
TAK-242 alleviates neuroinflammation and poststroke cognitive impairment by targeting the TLR4/SYK/NF-κB pathway in a cerebral ischemia/reperfusion rat model
inferred← citeshttps://doi.org/10.1016/j.ejphar.2026.178951openalex-snapshot
Resveratrol modulates the sFRP4/Wnt signaling Pathway and preserves blood-brain barrier integrity in rats with ischemic stroke
inferred← citeshttps://doi.org/10.1016/j.expneurol.2023.114548openalex-snapshot
Absence of chordin-like 1 aids motor recovery in a mouse model of stroke
inferred← citeshttps://doi.org/10.1016/j.expneurol.2025.115215openalex-snapshot
A pharmacological vasoconstrictor cocktail targeting endothelin signalling generates a stable, reproducible focal cerebral infarct with associated functional deficits in mice
inferred← citeshttps://doi.org/10.1016/j.expneurol.2026.116028openalex-snapshot
Intermittent theta-burst stimulation in ischemic stroke: a mitochondria-centered framework connecting microglial reprogramming and neuronal survival
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2022.11.021openalex-snapshot
Modulation of oxidative neurometabolism in ischemia/reperfusion by nitrite
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2025.12.005openalex-snapshot
Decreased OPA1 expression increases neuronal vulnerability to ischaemic stroke during ageing: Role of Timm8b as a therapeutic target
inferred← citeshttps://doi.org/10.1016/j.heliyon.2022.e10948openalex-snapshot
Monocyte-to-lymphocyte ratio affects prognosis in LAA-type stroke patients
inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e14692openalex-snapshot
A Canine Thromboembolic Model of Anterior Circulation Large Vessel Occlusion Stroke
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e24757openalex-snapshot
Research hotspots and frontiers of preconditioning in cerebral ischemia: A bibliometric analysis
inferred← citeshttps://doi.org/10.1016/j.heliyon.2025.e42457openalex-snapshot
Pharmacological inhibition of carbonic anhydrases with a positively charged pyridinium sulfonamide phenocopies the neuroprotective effects of Car9 genetic ablation in a murine setting of oxygen/glucose deprivation followed by re-oxygenation and is associated with improved neuronal function in…
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2026.127020openalex-snapshot
Stage-adaptive nanotherapeutic design for blood–brain barrier navigation in ischemic stroke
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.114229openalex-snapshot
ALPK1 signaling pathway activation by HMGB1 drives microglial pyroptosis and ferroptosis and brain injury after acute ischemic stroke
inferred← citeshttps://doi.org/10.1016/j.isci.2021.103539openalex-snapshot
Glycine-induced NMDA receptor internalization provides neuroprotection and preserves vasculature following ischemic stroke
inferred← citeshttps://doi.org/10.1016/j.isci.2022.104470openalex-snapshot
Nt5e deficiency does not affect post-stroke inflammation and lesion size in a murine ischemia/reperfusion stroke model
inferred← citeshttps://doi.org/10.1016/j.jchemneu.2022.102122openalex-snapshot
Topography of neurotrophins in the rat neocortex and their role in neuron apoptosis after experimental ischemic stroke
inferred← citeshttps://doi.org/10.1016/j.jchemneu.2023.102309openalex-snapshot
Exosome-shuttled MYCBPAP from bone marrow mesenchymal stem cells regulates synaptic remodeling and ameliorates ischemic stroke in rats
inferred← citeshttps://doi.org/10.1016/j.jcyt.2021.03.005openalex-snapshot
The effects of intravenous infusion of autologous mesenchymal stromal cells in patients with subacute middle cerebral artery infarct: a phase 2 randomized controlled trial on safety, tolerability and efficacy
inferred← citeshttps://doi.org/10.1016/j.jddst.2024.106292openalex-snapshot
An insight into fisetin, the miraculous multifaceted flavonol: Paving the road for enhanced delivery through promising pharmaceutical nano-formulations
inferred← citeshttps://doi.org/10.1016/j.jep.2020.113284openalex-snapshot
Abatement of neurobehavioral and neurochemical dysfunctions in cerebral ischemia/reperfusion injury by Tetrapleura tetraptera fruit extract
inferred← citeshttps://doi.org/10.1016/j.jep.2020.113410openalex-snapshot
Neuroprotection against cerebral ischemia/reperfusion by dietary phytochemical extracts from Tibetan turnip (Brassica rapa L.)
inferred← citeshttps://doi.org/10.1016/j.jep.2022.115301openalex-snapshot
Synergy of “Yiqi” and “Huoxue” components of QishenYiqi formula in ischemic stroke protection via lysosomal/inflammatory mechanisms
inferred← citeshttps://doi.org/10.1016/j.jep.2023.116898openalex-snapshot
Sanpian decoction ameliorates cerebral ischemia-reperfusion injury by regulating SIRT1/ERK/HIF-1α pathway through in silico analysis and experimental validation
inferred← citeshttps://doi.org/10.1016/j.jep.2026.121385openalex-snapshot
Salvia miltiorrhiza Bge. processed with porcine cardiac blood alleviates cerebral ischemia reperfusion injury through activating PPARγ/NF-κB pathway via suppressing arachidonic acid metabolism
inferred← citeshttps://doi.org/10.1016/j.jff.2018.04.054openalex-snapshot
Galangin’s potential as a functional food ingredient
inferred← citeshttps://doi.org/10.1016/j.jneumeth.2022.109630openalex-snapshot
Evaluating blood-brain barrier disruption and infarction volume concurrently in rats subjected to ischemic stroke using an optical imaging system
inferred← citeshttps://doi.org/10.1016/j.jneumeth.2024.110321openalex-snapshot
New approach to control ischemic severity ex vivo
inferred← citeshttps://doi.org/10.1016/j.jnrt.2026.100327openalex-snapshot
Multi-steroid interactions in ischemic stroke neuroprotection: a conceptual and mechanistic framework
inferred← citeshttps://doi.org/10.1016/j.jns.2019.116547openalex-snapshot
Considering risk factors for the effectiveness of translational therapies in brain stroke
inferred← citeshttps://doi.org/10.1016/j.jns.2020.117217openalex-snapshot
Strategies to prevent hemorrhagic transformation after reperfusion therapies for acute ischemic stroke: A literature review
inferred← citeshttps://doi.org/10.1016/j.jocn.2022.10.016openalex-snapshot
High-density lipoprotein level is associated with hemorrhage transformation after ischemic stroke treatment with intravenous thrombolysis: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.jstrokecerebrovasdis.2017.09.011openalex-snapshot
Disrupted Ionic Homeostasis in Ischemic Stroke and New Therapeutic Targets
inferred← citeshttps://doi.org/10.1016/j.jstrokecerebrovasdis.2019.06.034openalex-snapshot
Improvement in Microregional Oxygen Supply/Consumption Balance and Infarct Size After Cerebral Ischemia-Reperfusion With Inhibition of p70 Ribosomal S6 Kinase (S6K1)
inferred← citeshttps://doi.org/10.1016/j.jstrokecerebrovasdis.2020.105029openalex-snapshot
Lysophosphatidic acid increased infarct size in the early stage of cerebral ischemia-reperfusion with increased BBB permeability
inferred← citeshttps://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107942openalex-snapshot
Neuroprotective effects of Aframomum pruinosum seed extract against stroke in rat: Role of antioxidant and anti-inflammatory mechanisms
inferred← citeshttps://doi.org/10.1016/j.lfs.2020.117679openalex-snapshot
The impact of single and combined PPAR-α and PPAR-γ activation on the neurological outcomes following cerebral ischemia reperfusion
inferred← citeshttps://doi.org/10.1016/j.lfs.2022.121200openalex-snapshot
Zebrafish as a potential model for stroke: A comparative study with standardized models
inferred← citeshttps://doi.org/10.1016/j.lfs.2023.122358openalex-snapshot
Molecular mechanism of cognitive impairment associated with Parkinson's disease: A stroke perspective
inferred← citeshttps://doi.org/10.1016/j.mad.2019.111147openalex-snapshot
Ischemic stroke in neonatal and adult astrocytes
inferred← citeshttps://doi.org/10.1016/j.mad.2020.111361openalex-snapshot
Preclinical models of disease and multimorbidity with focus upon cardiovascular disease and dementia
inferred← citeshttps://doi.org/10.1016/j.medidd.2024.100197openalex-snapshot
Unlocking the therapeutic capabilities of GPCR in the treatment of ischemic stroke: A translational literature
inferred← citeshttps://doi.org/10.1016/j.medj.2024.03.018openalex-snapshot
Blocking cGAS-STING pathway promotes post-stroke functional recovery in an extended treatment window via facilitating remyelination
inferred← citeshttps://doi.org/10.1016/j.mtbio.2023.100674openalex-snapshot
Neutrophil membrane fusogenic nanoliposomal leonurine for targeted ischemic stroke therapy via remodeling cerebral niche and restoring blood-brain barrier integrity
inferred← citeshttps://doi.org/10.1016/j.nantod.2022.101707openalex-snapshot
Predicting thrombolytic haemorrhage risk of acute ischemic stroke through angiogenesis/inflammation dual-targeted MR imaging
inferred← citeshttps://doi.org/10.1016/j.nbd.2024.106586openalex-snapshot
Dystrophin 71 deficiency causes impaired aquaporin-4 polarization contributing to glymphatic dysfunction and brain edema in cerebral ischemia
inferred← citeshttps://doi.org/10.1016/j.neuint.2018.10.005openalex-snapshot
The effect of age, sex and strains on the performance and outcome in animal models of stroke
inferred← citeshttps://doi.org/10.1016/j.neuint.2018.11.011openalex-snapshot
Impact of C57BL/6 substrain on sex-dependent differences in mouse stroke models
inferred← citeshttps://doi.org/10.1016/j.neuint.2021.105138openalex-snapshot
Harnessing the mitochondrial integrity for neuroprotection: Therapeutic role of piperine against experimental ischemic stroke
inferred← citeshttps://doi.org/10.1016/j.neuint.2024.105881openalex-snapshot
MRPL41, as a target for acupuncture, promotes neuron apoptosis in models of ischemic stroke via activating p53 pathway
inferred← citeshttps://doi.org/10.1016/j.neulet.2025.138307openalex-snapshot
Sex-specific cell death mechanisms in rodent sub-acute and chronic stroke
inferred← citeshttps://doi.org/10.1016/j.neurobiolaging.2018.06.003openalex-snapshot
Sema3E/PlexinD1 inhibition is a therapeutic strategy for improving cerebral perfusion and restoring functional loss after stroke in aged rats
inferred← citeshttps://doi.org/10.1016/j.neuroimage.2024.120518openalex-snapshot
A toolkit for stroke infarct volume estimation in rodents
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2018.07.045openalex-snapshot
Emergent Uric Acid Treatment is Synergistic with Mechanical Recanalization in Improving Stroke Outcomes in Male and Female Rats
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2018.12.024openalex-snapshot
KY-226 Protects Blood–brain Barrier Function Through the Akt/FoxO1 Signaling Pathway in Brain Ischemia
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