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In vitro effects of bisphosphonates on chemotaxis, phagocytosis, and oxidative burst of neutrophil granulocytes

https://doi.org/10.1007/s00784-014-1219-0

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Bisphosphonates induce apoptosis in mouse macrophage-like cells in vitro by a nitric oxide-independent mechanism

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THe effects of suppressed bone remodeling by bisphosphonates on microdamage accumulation and degree of mineralization in the cortical bone of dog rib

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Long-Term Effects of Amino-Bisphosphonates on Circulating γδ T Cells

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An In Vitro and In Vivo Study of Cytokines in the Acute-Phase Response Associated with Bisphosphonates

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Actinomycosis of the jaws—histopathological study of 45 patients shows significant involvement in bisphosphonate-associated osteonecrosis and infected osteoradionecrosis

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Prevalence of bisphosphonate associated osteonecrosis of the jaw within the field of osteonecrosis

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Influence of bisphosphonates on endothelial cells, fibroblasts, and osteogenic cells

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Bisphosphonates: restrictions for vasculogenesis and angiogenesis: inhibition of cell function of endothelial progenitor cells and mature endothelial cells in vitro

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The influence of bisphosphonates on viability, migration, and apoptosis of human oral keratinocytes—in vitro study

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Radiologic bone loss in patients with bisphosphonate-associated osteonecrosis of the jaws: a case–control study

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Bisphosphonates’ antiangiogenic potency in the development of bisphosphonate-associated osteonecrosis of the jaws: influence on microvessel sprouting in an in vivo 3D Matrigel assay

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Bisphosphonate-associated osteonecrosis of the jaw: A key role of inflammation?

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Zoledronate inhibits the proliferation, adhesion and migration of vascular smooth muscle cells

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Prevalence and Risk Factors of Bisphosphonate-Associated Osteonecrosis of the Jaw in Prostate Cancer Patients with Advanced Disease Treated with Zoledronate

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Targeting Ras and Rho GTPases as opportunities for cancer therapeutics

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The effect of bisphosphonate therapy on neutrophil function: a potential biomarker

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Vγ9Vδ2 T cell-mediated non-cytolytic antiviral mechanisms and their potential for cell-based therapy

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Humanised mice have functional human neutrophils

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Avascular necrosis of the jaws: risk factors in metastatic cancer patients

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Bisphosphonate-Induced Osteonecrosis of the Jaws, Bone Markers, and a Hypothesized Candidate Gene

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Osteonecrosis of the Jaw: Effect of Bisphosphonate Type, Local Concentration, and Acidic Milieu on the Pathomechanism

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Human T Cell Receptor γδ Cells Recognize Endogenous Mevalonate Metabolites in Tumor Cells

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Fever After Zoledronic Acid Administration Is Due to Increase in TNF- α and IL-6

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Nitrogen Containing Bisphosphonates Induce Apoptosis and Inhibit the Mevalonate Pathway, Impairing Ras Membrane Localization in Prostate Cancer Cells

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Wound Healing: An Overview

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CC Chemokines Induce Neutrophils to Chemotaxis, Degranulation, and α-Defensin Release

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Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP

inferredcites →https://doi.org/10.1111/j.1365-2249.2005.02665.xopenalex-snapshot

The bisphosphonate acute phase response: rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins

inferredcites →https://doi.org/10.1111/j.1476-5381.2011.01592.xopenalex-snapshot

Zoledronate and pamidronate depress neutrophil functions and survival in mice

inferredcites →https://doi.org/10.1111/j.1600-0609.2007.00872.xopenalex-snapshot

Oral sodium clodronate induced osteonecrosis of the jaw in a patient with myeloma

inferredcites →https://doi.org/10.1111/j.1600-0757.1995.tb00038.xopenalex-snapshot

Diagnosis of periodontal disease based on analysis of the host response

inferredcites →https://doi.org/10.1111/j.1601-0825.2010.01720.xopenalex-snapshot

Bisphosphonates affect migration ability and cell viability of HUVEC, fibroblasts and osteoblasts in vitro

inferredcites →https://doi.org/10.1158/1078-0432.ccr-12-0489openalex-snapshot

Novel Aspects of Mevalonate Pathway Inhibitors as Antitumor Agents

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The Junctional Epithelium: from Health to Disease

inferredcites →https://doi.org/10.1182/blood-2005-03-0944openalex-snapshot

Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils

inferredcites →https://doi.org/10.1182/blood-2005-03-1025openalex-snapshot

Alkylamines cause Vγ9Vδ2 T-cell activation and proliferation by inhibiting the mevalonate pathway

inferredcites →https://doi.org/10.1182/blood-2008-04-147884openalex-snapshot

Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis

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Activation of C-C β-chemokines in human peripheral blood γδ T cells by isopentenyl pyrophosphate and regulation by cytokines

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Stimulation of γδ T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma

inferredcites →https://doi.org/10.1210/er.2007-0038openalex-snapshot

Osteoimmunology: Interactions of the Bone and Immune System

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Statins Prevent Bisphosphonate-Induced γ,δ-T-Cell Proliferation and Activation In Vitro

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Differentiation, Distribution and γδ T Cell-Driven Regulation of IL-22-Producing T Cells in Tuberculosis

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New Insights Into the Molecular Mechanisms of Action of Bisphosphonates

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Small Molecules for the Activation of Human γ δ T Cell Responses Against Infection

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Single-cell cytokine analysis of gamma delta T cell responses to nonpeptide mycobacterial antigens

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Activated Vγ9Vδ2 T Cells Trigger Granulocyte Functions via MCP-2 Release

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Paradoxical side effects of bisphosphonates on the skeleton: What do we know and what can we do?

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Bisphosphonates inhibit cell functions of HUVECs, fibroblasts and osteogenic cells via inhibition of protein geranylgeranylation

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Periosteal microcirculatory reactions in a zoledronate-induced osteonecrosis model of the jaw in rats

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Zoledronate but not denosumab suppresses macrophagic differentiation of THP-1 cells. An aetiologic model of bisphosphonate-related osteonecrosis of the jaw (BRONJ)

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Isoprenoid geranylgeraniol: the influence on cell characteristics of endothelial progenitor cells after bisphosphonate therapy in vitro

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The influence of geranylgeraniol on microvessel sprouting after bisphosphonate substitution in an in vitro 3D-angiogenesis assay

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Mechanical loading increases pro-inflammatory effects of nitrogen-containing bisphosphonate in human periodontal fibroblasts

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Diabetes mellitus and its association with infection and osteonecrosis of the jaw

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The influence of geranylgeraniol on human oral keratinocytes after bisphosphonate treatment: An in vitro study

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Untreated Apical Periodontitis and the Risk of Medication-related Osteonecrosis of the Jaws (MRONJ): A Systematic Review with Mechanistic Insights from Preclinical Studies

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Nationwide Multicentric Retrospective and Prospective Epidemiologic Survey of Bisphosphonate-related Osteonecrosis of the Jaws

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