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Medication Non-adherence is Associated with Increased Medical Health Care Costs

https://doi.org/10.1007/s10620-007-9968-0
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Barriers to HAART Adherence Among Human Immunodeficiency Virus–Infected Adolescents
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Vagal Nerve Stimulation in Refractory Epilepsy
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Clinicians and patients with hypertension: Unsettled issues about compliance
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A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation
inferredcites →https://doi.org/10.1016/0895-4356(92)90133-8openalex-snapshot
Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases
inferredcites →https://doi.org/10.1016/s0002-9270(01)03245-2openalex-snapshot
Prevalence of nonadherence with maintenance mesalamine in quiescent ulcerative colitis
inferredcites →https://doi.org/10.1016/s0002-9270(99)00904-1openalex-snapshot
Direct hospital costs for patients with inflammatory bowel disease in a Canadian Tertiary Care University Hospital
inferredcites →https://doi.org/10.1016/s0002-9343(02)01383-9openalex-snapshot
Medication nonadherence and the outcomes of patients with quiescent ulcerative colitis
inferredcites →https://doi.org/10.1016/s0002-9343(98)00297-6openalex-snapshot
Helicobacter pylori: rational management options
inferredcites →https://doi.org/10.1097/00004836-199206000-00009openalex-snapshot
Inflammatory Bowel Disease
inferredcites →https://doi.org/10.1097/00005650-200209000-00009openalex-snapshot
Patient Adherence and Medical Treatment Outcomes
inferredcites →https://doi.org/10.2337/diacare.27.5.1218openalex-snapshot
A Systematic Review of Adherence With Medications for Diabetes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Business Model Innovation in the Pharmaceutical Industry: The Supporting Role of Organizational Design
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Patient Adherence
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Gastrointestinal Diseases
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Non‐adherence to Medical Treatment
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HIGHLIGHTING DIFFERENCES BETWEEN CONDITIONAL AND UNCONDITIONAL QUANTILE REGRESSION APPROACHES THROUGH AN APPLICATION TO ASSESS MEDICATION ADHERENCE
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Impact and risk factors of non-adherence to 5-aminosalicylates in quiescent ulcerative colitis evaluated by an electronic management system
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Twelve-Month Persistency with Oral 5-Aminosalicylic Acid Therapy for Ulcerative Colitis: Results from a Large Pharmacy Prescriptions Database
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Medication Nonadherence in Parkinson’s Disease
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Efficacy, Safety, Patient Experience, and Tolerability of Risankizumab Administered by On-Body Injector for Moderate to Severe Crohn’s Disease
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A Pilot Study of a Text Messaging Intervention to Modify Illness and Medication Beliefs Among Patients Diagnosed with Inflammatory Bowel Disease
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Predictors of Medication Adherence Using a Multidimensional Adherence Model in Patients With Heart Failure
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A 38-Year-Old With Recurrent Colitis. Is It Noncompliance?
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Antihypertensive Prescribing for Uncomplicated, Incident Hypertension: Opportunities for Cost Savings
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Impact of a patient-support program on mesalamine adherence in patients with ulcerative colitis — A prospective study
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National differences in ulcerative colitis experience and management among patients from five European countries and Canada: An online survey
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Conveying medication benefits to ulcerative colitis patients and effects on patient attitudes regarding thresholds for adherence
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Cost and quality-adjusted life year differences in the treatment of active ulcerative colitis using once-daily 4g or twice-daily 2g mesalazine dosing
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New tools and approaches for improved management of inflammatory bowel diseases
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Abandono del tratamiento farmacológico asociado al coste. Encuesta Nacional de Salud y Envejecimiento de México 2015-2021
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Impact of pain associated with the subcutaneous administration of adalimumab
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Impact of pain associated with the subcutaneous administration of adalimumab
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Targeted colonic release formulations of mesalazine – A clinical pharmaco-scintigraphic proof-of-concept study in healthy subjects and patients with mildly active ulcerative colitis
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Impact of a pharmacist-led, primary medication nonadherence intervention program on prescription fills in underserved patient populations
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Telephone nurse counseling for medication adherence in ulcerative colitis: A preliminary study
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Psychosocial predictors of DMARD adherence in the first three months of treatment for early arthritis
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Interventions to improve medication adherence in inflammatory bowel disease: A systematic review
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Moving to a culture of health
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Marital status, State policy environment and Foregone healthcare of same-sex families during the COVID-19 period
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Emergency department care of seizure patients: Demographic trends in southern Arizona
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Adhesión a los tratamientos: un punto crítico
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DOP044 Patient education in a 14 month randomized trial fails to improve adherence in ulcerative colitis: Influence of demographic and clinical parameters on non-adherence
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Ulcerative Colitis Practice Guidelines in Adults: American College of Gastroenterology, Practice Parameters Committee
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Use of a Screening Tool to Determine Nonadherent Behavior in Inflammatory Bowel Disease
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A Random Urine Test Can Identify Patients at Risk of Mesalamine Non-Adherence: A Prospective Study
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Attitudes to Mesalamine Questionnaire: A Novel Tool to Predict Mesalamine Nonadherence in Patients with IBD
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Patients’ and professionals’ preferences in terms of the attributes of home enteral nutrition products in Spain. A discrete choice experiment
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Assessing the repercussions of COVID-19 pandemic on symptoms, disease management, and emotional well-being in patients with inflammatory bowel disease: a multi-site survey study
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Adherence to Psychotropic Medications and Associated Factors in Primary Health Care
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Factors associated with poor compliance amongst hospitalized, predominantly adolescent pediatric Crohn’s disease patients
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Is regular in-person recall superior to non-regular in-person recall in clinical outcomes among new patients undergoing peritoneal dialysis
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The problem of adherence to therapy in ulcerative colitis and the potential utility of multi-matrix system (MMX) technology
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Medication non-adherence in adult patients affected by inflammatory bowel disease: a critical review and update of the determining factors, consequences and possible interventions
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Patients with inflammatory bowel disease (IBD) prefer oral tablets over other modes of medicine administration
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Analysis of systemic and behavioral barriers to COVID-19 vaccination in rollout phase
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Improving Medication Adherence and Health Care Outcomes in a Commercial Population through a Community Pharmacy
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Comparing the Predictive Effects of Patient Medication Adherence Indices in Electronic Health Record and Claims-Based Risk Stratification Models
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Business Model Innovation in the Pharmaceutical Industry
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Patient Education in a 14-month Randomised Trial Fails to Improve Adherence in Ulcerative Colitis: Influence of Demographic and Clinical Parameters on Non-adherence
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Outcomes and Strategies to Support a Treat-to-target Approach in Inflammatory Bowel Disease: A Systematic Review
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Case control study of access to medications during COVID-19 and longitudinal impact on health outcomes for primary care patients managing multiple chronic conditions
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The Accuracy of Adherence Self-report Scales in Patients on Thiopurines for Inflammatory Bowel Disease: A Comparison With Drug Metabolite Levels and Medication Possession Ratios
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Live Like Nobody Is Watching
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Copyright Page
inferred← citeshttps://doi.org/10.1093/med/9780197556269.002.0005openalex-snapshot
Preface
inferred← citeshttps://doi.org/10.1093/med/9780197556269.002.0007openalex-snapshot
Abbreviations
inferred← citeshttps://doi.org/10.1093/med/9780197556269.002.0014openalex-snapshot
Epilogue
inferred← citeshttps://doi.org/10.1093/med/9780197556269.003.0001openalex-snapshot
Introduction
inferred← citeshttps://doi.org/10.1093/med/9780197556269.003.0002openalex-snapshot
Artificial Autonomy or Relational Intelligence
inferred← citeshttps://doi.org/10.1093/med/9780197556269.003.0003openalex-snapshot
Independent Living With(out) Privacy
inferred← citeshttps://doi.org/10.1093/med/9780197556269.003.0004openalex-snapshot
Artificial Doctoring
inferred← citeshttps://doi.org/10.1093/med/9780197556269.003.0005openalex-snapshot
A Digital Pill to Swallow
inferred← citeshttps://doi.org/10.1093/med/9780197556269.003.0006openalex-snapshot
From One-Way Mirror to Two-Way Street
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Medical resource utilization and associated costs in patients with ulcerative colitis in the UK
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Implementable Strategies and Exploratory Considerations to Reduce Costs Associated with Anti-TNF Therapy in Inflammatory Bowel Disease
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Identifying predictors of low adherence in patients with inflammatory bowel disease
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Adherence to Rectal Mesalamine in Patients with Ulcerative Colitis
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Treatment Nonadherence in Inflammatory Bowel Disease
inferred← citeshttps://doi.org/10.1097/mib.0000000000001165openalex-snapshot
Longitudinal Patterns of Medication Nonadherence and Associated Health Care Costs
inferred← citeshttps://doi.org/10.1097/mib.0b013e318280b1b8openalex-snapshot
Long-Term Mesalamine Maintenance in Ulcerative Colitis
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Adherence to Anti-TNF Therapy in Inflammatory Bowel Diseases
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Practical Strategies for Enhancing Adherence to Treatment Regimen in Inflammatory Bowel Disease
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Modifiable Factors Associated with Nonadherence to Maintenance Medication for Inflammatory Bowel Disease
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Standardizing Terminology and Definitions of Medication Adherence and Persistence in Research Employing Electronic Databases
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Remission in Pediatric Inflammatory Bowel Disease Correlates With Prescription Refill Adherence Rates
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Text Messaging Effect on Adherence in Children With Inflammatory Bowel Disease
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Benefits of Structured Pediatric to Adult Transition in Inflammatory Bowel Disease: The TRANSIT Observational Study.
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Health Supervision in the Management of Children and Adolescents With IBD
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Adherence to Intravenous Chemotherapy in African American and White Women With Early-Stage Breast Cancer
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Long‐term oral mesalazine adherence and the risk of disease flare in ulcerative colitis: nationwide 10‐year retrospective cohort from the veterans affairs healthcare system
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Commentary: 5-ASA switches in IBD, adherence and flares
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Factors associated with thiopurine non-adherence in patients with inflammatory bowel disease
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Longitudinal non‐adherence predicts treatment escalation in paediatric ulcerative colitis
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Clinical Trial: Evaluating a Single 1600 mg Tablet Regimen of 5‐Aminosalicylate for Ulcerative Colitis—The EASI Trial
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Systematic review: impact of non‐adherence to 5‐aminosalicylic acid products on the frequency and cost of ulcerative colitis flares
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Self‐reported antenatal adherence to medical treatment among pregnant women with Crohn’s disease
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Review article: understanding adherence to medication in ulcerative colitis – innovative thinking and evolving concepts
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Mesalazine granules 1.5 g once‐daily maintain remission in patients with ulcerative colitis who switch from other 5‐ ASA formulations: a pooled analysis from two randomised controlled trials
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Medication non‐adherence—exploring the conceptual mire
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Impact of nonadherence to antiepileptic drugs on health care utilization and costs: Findings from the RANSOM study
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Self-management for patients with inflammatory bowel disease in a gastroenterology ward in China: a best practice implementation project
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The Role of Artificial Intelligence in Deciphering Diet–Disease Relationships: Case Studies
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Treatment Adherence in Inflammatory Bowel Disease Patients from Argentina: A Multicenter Study
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Patients’ Educational Program Could Improve Azathioprine Adherence in Crohn’s Disease Maintenance Therapy
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Debt and Foregone Medical Care
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The Role of Depression in Medication Adherence Among Heart Failure Patients
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Re‐phrasing the question: A simple tool for evaluation of adherence to therapy in patients with inflammatory bowel disease
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Perception gaps between patients with ulcerative colitis and healthcare professionals: an online survey
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Medicines discarded in household garbage: analysis of a pharmaceutical waste sample in Vienna
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The effect of low insurance reimbursement on quality of care for non-small cell lung cancer in China: a comprehensive study covering diagnosis, treatment, and outcomes
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Oft veltir lítil þúfa þungu hlassi: Sjálfræðisréttur skjólstæðinga, vanlíðan vegna frávika og traust innan heilbrigðisþjónustu
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Treatment Profile of Pediatric Inflammatory Bowel Disease in Saudi Arabia: Issues in Treatment Adherence
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Medication adherence: Pharmacist perspective
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Non-Adherence in Patients on Peritoneal Dialysis: A Systematic Review
inferred← citeshttps://doi.org/10.1371/journal.pone.0124275openalex-snapshot
The Malaysian Medication Adherence Scale (MALMAS): Concurrent Validity Using a Clinical Measure among People with Type 2 Diabetes in Malaysia
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Targeting Medication Non-Adherence Behavior in Selected Autoimmune Diseases: A Systematic Approach to Digital Health Program Development
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Nonadherence to Medication Therapy in Haemodialysis Patients: A Systematic Review
inferred← citeshttps://doi.org/10.1371/journal.pone.0145076openalex-snapshot
Interventions to Improve Adherence in Patients with Immune-Mediated Inflammatory Disorders: A Systematic Review
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Does non-adherence to DMARDs influence hospital-related healthcare costs for early arthritis in the first year of treatment?
inferred← citeshttps://doi.org/10.1371/journal.pone.0255620openalex-snapshot
Predictive factors of relapse after dose reduction of oral 5-aminosalicylic acid in patients with ulcerative colitis in the remission phase
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Costs of outpatient services at selected primary healthcare centers in Bangladesh: A cross-sectional study
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Adherence to intravenous chemotherapy and associated factors among patients with cancer at Hawassa University Comprehensive Specialized Hospital Cancer Treatment Center, Sidama Region, Southern Ethiopia
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Medication Adherence Leads To Lower Health Care Use And Costs Despite Increased Drug Spending
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Food Insecurity Is Associated With Higher Health Care Use And Costs Among Canadian Adults
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Clinical impact and drivers of non-adherence to maintenance medication for inflammatory bowel disease
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Nonadherence to Medication in Inflammatory Bowel Disease: Rate and Reasons
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Persistence to oral 5-aminosalicylate therapy for inflammatory bowel disease in Australia
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Once-daily mesalamine granules for ulcerative colitis
inferred← citeshttps://doi.org/10.1586/eci.10.28openalex-snapshot
Insight into the widespread problem of nonadherence to therapy in ulcerative colitis patients
inferred← citeshttps://doi.org/10.1586/ecp.12.2openalex-snapshot
Mesalamine in the treatment and maintenance of remission of ulcerative colitis
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Observance thérapeutique et maladies inflammatoires chroniques intestinales
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Assessing medication adherence in inflammatory bowel diseases. A comparison between a self-administered scale and a pharmacy refill index
inferred← citeshttps://doi.org/10.17615/xgt3-ds64openalex-snapshot
DO AS I SAY; NOT AS I DO: A COHORT STUDY OF COMMERCIALLY INSURED FAMILIES AND THE RELATIONSHIP BETWEEN PRIOR PARENTAL ADHERENCE AND FUTURE CHILD ADHERENCE AND PERSISTENCE TO TREATMENT ACROSS FIVE CHRONIC CONDITIONS
inferred← citeshttps://doi.org/10.18553/jmcp.2026.32.1.27openalex-snapshot
Predicting self-administered biologic nonadherence in Medicare fee-for-service beneficiaries with inflammatory bowel disease using machine learning models
inferred← citeshttps://doi.org/10.20538/1682-0363-2021-3-120-128openalex-snapshot
Adherence to treatment in patients with inflammatory bowel disease
inferred← citeshttps://doi.org/10.2147/ceg.s237653openalex-snapshot
Patient Preference and Adherence to Aminosalicylates for the Treatment of Ulcerative Colitis
inferred← citeshttps://doi.org/10.2147/ceg.s35942openalex-snapshot
Current approaches to the management of new-onset ulcerative colitis
inferred← citeshttps://doi.org/10.2147/ceg.s6439openalex-snapshot
Cause for controversy? Infliximab in the treatment of ulcerative colitis: an update
inferred← citeshttps://doi.org/10.2147/cpaa.s26556openalex-snapshot
Update on the management of ulcerative colitis: treatment and maintenance approaches focused on MMX® mesalamine
inferred← citeshttps://doi.org/10.2147/ppa.s127039openalex-snapshot
Adherence in ulcerative colitis: an overview
inferred← citeshttps://doi.org/10.2147/ppa.s31115openalex-snapshot
Effect of a continuous measure of adherence with infliximab maintenance treatment on inpatient outcomes in Crohn's disease
inferred← citeshttps://doi.org/10.2147/ppa.s486974openalex-snapshot
Obstacles to Medication Adherence for Patients with Inflammatory Bowel Disease: A Qualitative Study in East China
inferred← citeshttps://doi.org/10.2147/prom.s8382openalex-snapshot
Optimizing use of 5-ASA in the treatment of ulcerative colitis: Focus on patient compliance and adherence
inferred← citeshttps://doi.org/10.2165/0003495-200868180-00006openalex-snapshot
Strategies to Improve Adherence and Outcomes in Patients with Ulcerative Colitis
inferred← citeshttps://doi.org/10.2165/11205870-000000000-00000openalex-snapshot
MMX® Mesalazine
inferred← citeshttps://doi.org/10.2196/19179openalex-snapshot
Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review
inferred← citeshttps://doi.org/10.2196/28978openalex-snapshot
Role of Telemedicine in Inflammatory Bowel Disease: Systematic Review and Meta-analysis of Randomized Controlled Trials
inferred← citeshttps://doi.org/10.2196/46979openalex-snapshot
Co-Design, Development, and Evaluation of a Mobile Solution to Improve Medication Adherence in Cancer: Design Science Research Approach
inferred← citeshttps://doi.org/10.2196/mhealth.3987openalex-snapshot
Don’t Forget the Doctor: Gastroenterologists’ Preferences on the Development of mHealth Tools for Inflammatory Bowel Disease
inferred← citeshttps://doi.org/10.2196/preprints.28978openalex-snapshot
Role of Telemedicine in Inflammatory Bowel Disease: a Systematic Review and Meta-analysis of Randomized Clinical Trials (Preprint)
inferred← citeshttps://doi.org/10.26442/00403660.2018.12.000001openalex-snapshot
Adherence to therapy of patients with inflammatory bowel diseases
inferred← citeshttps://doi.org/10.3109/00365521.2012.743584openalex-snapshot
Medication use among inflammatory bowel disease patients: excessive consumption of antidepressants and analgesics
inferred← citeshttps://doi.org/10.3109/00365521.2014.920913openalex-snapshot
Self-reported adherence to medical treatment, breastfeeding behaviour, and disease activity during the postpartum period in women with Crohn’s disease
inferred← citeshttps://doi.org/10.3111/13696998.2014.964406openalex-snapshot
How costly is non-adherence to infliximab in patients with Crohn’s disease?
inferred← citeshttps://doi.org/10.31146/1682-8658-ecg-162-2-125-130openalex-snapshot
Ulcerative colitis: features of the course and adherence to prescribed therapy in adolescents
inferred← citeshttps://doi.org/10.31146/1682-8658-ecg-192-8-134-141openalex-snapshot
Potential adherence to treatment in gastroenterological patients
inferred← citeshttps://doi.org/10.3389/fphar.2022.1062728openalex-snapshot
Prevalence and predictors of medication non-adherence in children with inflammatory bowel disease in China: A cross-sectional study
inferred← citeshttps://doi.org/10.3389/fphar.2023.1185026openalex-snapshot
The impact of medication belief on adherence to infliximab in patients with Crohn’s disease
inferred← citeshttps://doi.org/10.3389/fphar.2024.1448986openalex-snapshot
Association between medication complexity and follow-up care attendance: insights from a retrospective multicenter cohort study across 1,223 Chinese hospitals
inferred← citeshttps://doi.org/10.3389/frhs.2025.1654520openalex-snapshot
Rectal treatment in ulcerative colitis; a qualitative study exploring reasons for under utilisation
inferred← citeshttps://doi.org/10.3390/healthcare11192642openalex-snapshot
Impact of the COVID-19 Pandemic on the Lifestyle and Psychosocial Behavior of Patients with Inflammatory Bowel Diseases: A Narrative Review
inferred← citeshttps://doi.org/10.3390/jpm15040123openalex-snapshot
Non-Adherence Rate to Oral Mesalamine in Ulcerative Colitis Patients: A Systematic Review with Meta-Analysis
inferred← citeshttps://doi.org/10.3390/ph18121876openalex-snapshot
Safety, Pharmacokinetics, and Bioequivalence Characterization of Two Different Strengths of Mesalazine Gastro-Resistant Tablets
inferred← citeshttps://doi.org/10.3862/jcoloproctology.76.580openalex-snapshot
The Forefront of Drug Therapy for Ulcerative Colitis
inferred← citeshttps://doi.org/10.4103/jrms.jrms_866_16openalex-snapshot
Factors associated with adherence to treatment in Iranian patients with inflammatory bowel disease
inferred← citeshttps://doi.org/10.4140/tcp.n.2013.793openalex-snapshot
Effects of Health Literacy and Polypharmacy on Medication Adherence
inferred← citeshttps://doi.org/10.4292/wjgpt.v8.i1.67openalex-snapshot
Current practice and clinicians’ perception of medication non-adherence in patients with inflammatory bowel disease: A survey of 98 clinicians
inferred← citeshttps://doi.org/10.5217/ir.2017.15.4.434openalex-snapshot
Medication adherence in inflammatory bowel disease
inferred← citeshttps://doi.org/10.5217/ir.2018.00033openalex-snapshot
Medication non-adherence in inflammatory bowel diseases is associated with disability
inferred← citeshttps://doi.org/10.5217/ir.2018.00099openalex-snapshot
Health-related quality of life of patients with inflammatory bowel disease in Singapore
inferred← citeshttps://doi.org/10.5530/ijper.53.4s.143openalex-snapshot
Difficulties Facing the Patients and Extra Burden for Healthcare Providers by Non-adherence to the Medications - A Comprehensive Review
inferred← citeshttps://doi.org/10.5603/mrj.2017.0015openalex-snapshot
Self-reported questionnaires for assessment adherence to treatment in patients with cardiovascular diseases
inferred← citeshttps://doi.org/10.5603/mrj.2017.0016openalex-snapshot
Adherence to treatment — a pivotal issue in long-term treatment of patients with cardiovascular diseases. An expert standpoint
inferred← citeshttps://doi.org/10.58775/2735-3990.1371openalex-snapshot
Impact of COVID - 19 Pandemic on The Clinical Course of Inflammatory Bowel Disease in Egyptian Tertiary Centers
inferred← citeshttps://doi.org/10.7759/cureus.92901openalex-snapshot
A Comprehensive Review of the Role of Biologics and Small-Molecule Therapies in the Long-Term Management of Crohn’s Disease
inferred← citeshttps://doi.org/10.7897/2230-8407.1007215openalex-snapshot
EFFECTIVENESS OF COUNSELING FOR HYPERTENSIVE PATIENTS ON ADHERENCE AND BLOOD PRESSURE OUTCOME IN PRIMARY CARE PROVIDER IN INDONESIA
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.