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Serologic Cross-Reactivity of SARS-CoV-2 with Endemic and Seasonal Betacoronaviruses

https://doi.org/10.1007/s10875-021-00997-6
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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SARS‐CoV‐2 Seroconversion in Humans: A Detailed Protocol for a Serological Assay, Antigen Production, and Test Setup
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inferredcites →https://doi.org/10.1038/s41591-020-0897-1openalex-snapshot
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inferredcites →https://doi.org/10.1073/pnas.1707304114openalex-snapshot
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen
inferredcites →https://doi.org/10.1093/infdis/jiaa743openalex-snapshot
Effect of D614G Spike Variant on Immunoglobulin G, M, or A Spike Seroassay Performance
inferredcites →https://doi.org/10.1101/2020.03.24.006544openalex-snapshot
Analysis of Serologic Cross-Reactivity Between Common Human Coronaviruses and SARS-CoV-2 Using Coronavirus Antigen Microarray
inferredcites →https://doi.org/10.1101/2020.04.24.057323openalex-snapshot
Validation of a SARS-CoV-2 spike protein ELISA for use in contact investigations and sero-surveillance
inferredcites →https://doi.org/10.1126/sciadv.aav4580openalex-snapshot
A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike
inferredcites →https://doi.org/10.1126/science.abb2507openalex-snapshot
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
inferredcites →https://doi.org/10.1126/science.abb7269openalex-snapshot
A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
inferredcites →https://doi.org/10.1126/scitranslmed.abh3826openalex-snapshot
Undiagnosed SARS-CoV-2 seropositivity during the first 6 months of the COVID-19 pandemic in the United States
inferredcites →https://doi.org/10.1128/cvi.00278-10openalex-snapshot
Prevalence of Antibodies to Four Human Coronaviruses Is Lower in Nasal Secretions than in Serum
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Epidemiology and Clinical Presentations of the Four Human Coronaviruses 229E, HKU1, NL63, and OC43 Detected over 3 Years Using a Novel Multiplex Real-Time PCR Method
inferredcites →https://doi.org/10.1128/jvi.77.16.8801-8811.2003openalex-snapshot
The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex
inferredcites →https://doi.org/10.1146/annurev-virology-110615-042301openalex-snapshot
Structure, Function, and Evolution of Coronavirus Spike Proteins
inferredcites →https://doi.org/10.1155/2006/152612openalex-snapshot
An Outbreak of Human Coronavirus OC43 Infection and Serological Cross‐Reactivity with SARS Coronavirus

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Colostrum from MERS-CoV seropositive camels for MERS prophylaxis and SARS-CoV-2 infection, a placebo controlled randomized trial
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SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus
inferred← citeshttps://doi.org/10.1073/pnas.2108395118openalex-snapshot
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Human type I IFN deficiency does not impair B cell response to SARS-CoV-2 mRNA vaccination
inferred← citeshttps://doi.org/10.1093/cid/ciab607openalex-snapshot
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inferred← citeshttps://doi.org/10.1093/infdis/jiaa743openalex-snapshot
Effect of D614G Spike Variant on Immunoglobulin G, M, or A Spike Seroassay Performance
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IgG Against Human Betacoronavirus Spike Proteins Correlates With SARS-CoV-2 Anti-Spike IgG Responses and COVID-19 Disease Severity
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Archived dengue serum samples produced false-positive results in SARS-CoV-2 lateral flow-based rapid antibody tests
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BANCOVID, the first D614G variant mRNA-based vaccine candidate against SARS-CoV-2 elicits neutralizing antibody and balanced cellular immune response
inferred← citeshttps://doi.org/10.1101/2020.10.05.20206664openalex-snapshot
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inferred← citeshttps://doi.org/10.1101/2020.10.08.332544openalex-snapshot
Neutralizing antibodies from early cases of SARS-CoV-2 infection offer cross-protection against the SARS-CoV-2 D614G variant
inferred← citeshttps://doi.org/10.1101/2020.10.14.20207050openalex-snapshot
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inferred← citeshttps://doi.org/10.1101/2021.05.12.21257125openalex-snapshot
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inferred← citeshttps://doi.org/10.1101/2025.10.17.682775openalex-snapshot
Serological evidence of SARS-CoV-2 infection in red and fallow deer in Great Britain
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False‐positive reactivity of fourth‐generation HIV enzyme immunoassay caused by COVID ‐19 and other infections
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Structural mapping of antibody landscapes to human betacoronavirus spike proteins
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Undiagnosed SARS-CoV-2 seropositivity during the first 6 months of the COVID-19 pandemic in the United States
inferred← citeshttps://doi.org/10.1128/jcm.02160-20openalex-snapshot
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inferred← citeshttps://doi.org/10.1128/mbio.03356-25openalex-snapshot
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inferred← citeshttps://doi.org/10.1128/msphere.00685-21openalex-snapshot
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inferred← citeshttps://doi.org/10.11606/d.5.2023.tde-07122023-181214openalex-snapshot
Prevalência e reatividade cruzada entre SARS-CoV-2 e HCoVs endêmicos
inferred← citeshttps://doi.org/10.1172/jci.insight.146316openalex-snapshot
A majority of uninfected adults show preexisting antibody reactivity against SARS-CoV-2
inferred← citeshttps://doi.org/10.1172/jci.insight.166602openalex-snapshot
Qualitative monitoring of SARS-CoV-2 mRNA vaccination in humans using droplet microfluidics
inferred← citeshttps://doi.org/10.1172/jci142804openalex-snapshot
COVID-19 survival associates with the immunoglobulin response to the SARS-CoV-2 spike receptor binding domain
inferred← citeshttps://doi.org/10.1172/jci155615openalex-snapshot
Family matters for coronavirus disease and vaccines
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Pre-pandemic antibodies screening against SARS-CoV-2 and virus detection among children diagnosed with eruptive fevers
inferred← citeshttps://doi.org/10.1177/08828245261474281openalex-snapshot
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inferred← citeshttps://doi.org/10.1177/17534259211043159openalex-snapshot
Neglected roles of IgG Fc-binding protein secreted from airway mucin-producing cells in protecting against SARS-CoV-2 infection
inferred← citeshttps://doi.org/10.1183/23120541.00025-2022openalex-snapshot
Trimer IgG and neutralising antibody response to COVID-19 mRNA vaccination in individuals with sarcoidosis
inferred← citeshttps://doi.org/10.1186/s12879-021-06233-1openalex-snapshot
Prospective Assessment of SARS-CoV-2 Seroconversion (PASS) study: an observational cohort study of SARS-CoV-2 infection and vaccination in healthcare workers
inferred← citeshttps://doi.org/10.1186/s12879-025-11974-4openalex-snapshot
A longitudinal study of antibody responses to endemic HCoV and novel SARS-CoV-2 among mother-child pairs in Zambia
inferred← citeshttps://doi.org/10.1186/s12879-026-13133-9openalex-snapshot
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inferred← citeshttps://doi.org/10.1186/s12915-024-02074-xopenalex-snapshot
Serological evidence of sarbecovirus exposure along Sunda pangolin trafficking pathways
inferred← citeshttps://doi.org/10.1186/s12917-025-04938-yopenalex-snapshot
Cross-neutralising antibodies to SARS-CoV-2 in sera from straw-coloured fruit bats (Eidolon helvum) in Nigeria
inferred← citeshttps://doi.org/10.1186/s12929-025-01193-zopenalex-snapshot
Human coronavirus OC43 infection in human cerebral organoids: novel insights on pathogenesis and potential therapeutic interventions
inferred← citeshttps://doi.org/10.1208/s12248-020-00510-8openalex-snapshot
Are Lessons Learned in Setting Cut Points for Detection of Anti-Drug Antibodies Also Useful in Serology Assays for Robust Detection of SARS-CoV-2 Reactive Antibodies?
inferred← citeshttps://doi.org/10.1371/journal.pone.0245382openalex-snapshot
Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients: An observational cohort study
inferred← citeshttps://doi.org/10.1371/journal.pone.0256482openalex-snapshot
Original antigenic sin responses to Betacoronavirus spike proteins are observed in a mouse model, but are not apparent in children following SARS-CoV-2 infection
inferred← citeshttps://doi.org/10.1371/journal.pone.0325923openalex-snapshot
Detectable SARS-CoV-2 specific immune responses in recovered unvaccinated individuals 250 days post wild type infection
inferred← citeshttps://doi.org/10.1371/journal.ppat.1009352openalex-snapshot
Breadth and function of antibody response to acute SARS-CoV-2 infection in humans
inferred← citeshttps://doi.org/10.14776/piv.2021.28.e10openalex-snapshot
Clinical and Epidemiological Characteristics of Common Human Coronaviruses in Children: A Single Center Study, 2015–2019
inferred← citeshttps://doi.org/10.1557/s43577-021-00167-4openalex-snapshot
Material strategies and considerations for serologic testing of global infectious diseases
inferred← citeshttps://doi.org/10.18632/aging.104166openalex-snapshot
Using the common cold virus as a naturally occurring vaccine to prevent COVID-19: Lessons from Edward Jenner
inferred← citeshttps://doi.org/10.21203/rs.3.rs-105768/v1openalex-snapshot
A betacoronavirus multiplex microsphere immunoassay detects early SARS-CoV-2 seroconversion and antibody cross reactions
inferred← citeshttps://doi.org/10.21203/rs.3.rs-142838/v1openalex-snapshot
Epidemiological Characteristics of Common Human Coronaviruses in Korea, 2015-2019
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3891128/v1openalex-snapshot
Lower Humoral and Cellular Immunity following Asymptomatic SARS-CoV-2 Infection in Education (The ACE Cohort)
inferred← citeshttps://doi.org/10.2174/1574887118666230413092826openalex-snapshot
SARS-CoV-2 Detection and COVID-19 Diagnosis: A Bird’s Eye View
inferred← citeshttps://doi.org/10.3201/eid2802.211725openalex-snapshot
SARS-CoV-2 Cross-Reactivity in Prepandemic Serum from Rural Malaria-Infected Persons, Cambodia
inferred← citeshttps://doi.org/10.3201/eid3211.260690openalex-snapshot
Serologic Testing for Middle East Respiratory Syndrome Coronavirus and SARS-CoV-2 Cross-Reactive Immune Responses, the Netherlands
inferred← citeshttps://doi.org/10.3233/hab-230017openalex-snapshot
Unravelling humoral immunity in SARS-CoV-2: Insights from infection and vaccination
inferred← citeshttps://doi.org/10.3389/fcimb.2022.978440openalex-snapshot
Pre-existing anti-HCoV-OC43 immunity influences the durability and cross-reactivity of humoral response to SARS-CoV-2 vaccination
inferred← citeshttps://doi.org/10.3389/fcimb.2025.1670219openalex-snapshot
Identification of dominant peptide epitopes and antibody response to the spike protein of SARS-CoV-2
inferred← citeshttps://doi.org/10.3389/fdgth.2022.903153openalex-snapshot
At-home blood collection and stabilization in high temperature climates using homeRNA
inferred← citeshttps://doi.org/10.3389/fimmu.2020.610688openalex-snapshot
Humoral Responses and Serological Assays in SARS-CoV-2 Infections
inferred← citeshttps://doi.org/10.3389/fimmu.2021.753435openalex-snapshot
Non-Invasive Antibody Assessment in Saliva to Determine SARS-CoV-2 Exposure in Young Children
inferred← citeshttps://doi.org/10.3389/fimmu.2021.775420openalex-snapshot
Persistence of Anti-SARS-CoV-2 Antibodies in Long Term Care Residents Over Seven Months After Two COVID-19 Outbreaks
inferred← citeshttps://doi.org/10.3389/fimmu.2022.836449openalex-snapshot
Age-Associated Seroprevalence of Coronavirus Antibodies: Population-Based Serosurveys in 2013 and 2020, British Columbia, Canada
inferred← citeshttps://doi.org/10.3389/fimmu.2022.839367openalex-snapshot
Heterologous Immune Responses of Serum IgG and Secretory IgA Against the Spike Protein of Endemic Coronaviruses During Severe COVID-19
inferred← citeshttps://doi.org/10.3389/fimmu.2022.902956openalex-snapshot
Individual and Synergistic Anti-Coronavirus Activities of SOCS1/3 Antagonist and Interferon α1 Peptides
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1138629openalex-snapshot
Convalescent human IgG, but not IgM, from COVID-19 survivors confers dose-dependent protection against SARS-CoV-2 replication and disease in hamsters
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1159326openalex-snapshot
Innate and adaptive immunity to SARS-CoV-2 and predisposing factors
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1401728openalex-snapshot
Seasonal human coronavirus humoral responses in AZD1222 (ChaAdOx1 nCoV-19) COVID-19 vaccinated adults reveal limited cross-immunity
inferred← citeshttps://doi.org/10.3389/fmed.2021.615099openalex-snapshot
Review of Current COVID-19 Diagnostics and Opportunities for Further Development
inferred← citeshttps://doi.org/10.3389/fmed.2021.770381openalex-snapshot
Long-Lasting Immunity Against SARS-CoV-2: Dream or Reality?
inferred← citeshttps://doi.org/10.3389/fped.2020.601327openalex-snapshot
Assessment of Seroconversion to SARS-CoV-2 in a Cohort of Pediatric Kidney Transplant Recipients
inferred← citeshttps://doi.org/10.3389/fped.2022.877759openalex-snapshot
Epidemiology and Clinical Characteristics of Human Coronaviruses-Associated Infections in Children: A Multi-Center Study
inferred← citeshttps://doi.org/10.3390/ani12030378openalex-snapshot
Diversity of Coronaviruses with Particular Attention to the Interspecies Transmission of SARS-CoV-2
inferred← citeshttps://doi.org/10.3390/antib12020035openalex-snapshot
Detection of SARS-CoV-2 Antibodies: Comparison of Enzyme Immunoassay, Surrogate Neutralization and Virus Neutralization Test
inferred← citeshttps://doi.org/10.3390/biology12101293openalex-snapshot
Individual Immune Response to SARS-CoV-2 Infection—The Role of Seasonal Coronaviruses and Human Leukocyte Antigen
inferred← citeshttps://doi.org/10.3390/cells10081843openalex-snapshot
Affinity Tag Coating Enables Reliable Detection of Antigen-Specific B Cells in Immunospot Assays
inferred← citeshttps://doi.org/10.3390/diagnostics11081506openalex-snapshot
Development and Evaluation of a Set of Spike and Receptor Binding Domain-Based Enzyme-Linked Immunosorbent Assays for SARS-CoV-2 Serological Testing
inferred← citeshttps://doi.org/10.3390/diagnostics14161776openalex-snapshot
The Protection Level of S-RBD SARS-CoV-2 Immunoglobulin G Antibodies Using the Chemiluminescent Immunoassay Compared to the Surrogate Virus Neutralization Test Method
inferred← citeshttps://doi.org/10.3390/ijms22052723openalex-snapshot
Towards Quantitative and Standardized Serological and Neutralization Assays for COVID-19
inferred← citeshttps://doi.org/10.3390/ijms23062977openalex-snapshot
Cross-Recognition of SARS-CoV-2 B-Cell Epitopes with Other Betacoronavirus Nucleoproteins
inferred← citeshttps://doi.org/10.3390/ijms25158180openalex-snapshot
Enhanced Assessment of Cross-Reactive Antigenic Determinants within the Spike Protein
inferred← citeshttps://doi.org/10.3390/ijtm2030024openalex-snapshot
Exploring the Role of Serology Testing to Strengthen Vaccination Initiatives and Policies for COVID-19 in Asia Pacific Countries and Territories: A Discussion Paper
inferred← citeshttps://doi.org/10.3390/life11040298openalex-snapshot
Previous Humoral Immunity to the Endemic Seasonal Alphacoronaviruses NL63 and 229E Is Associated with Worse Clinical Outcome in COVID-19 and Suggests Original Antigenic Sin
inferred← citeshttps://doi.org/10.3390/life11070660openalex-snapshot
Analytical Performance of COVID-19 Detection Methods (RT-PCR): Scientific and Societal Concerns
inferred← citeshttps://doi.org/10.3390/microorganisms10020429openalex-snapshot
Assessment of Diagnostic Specificity of Anti-SARS-CoV-2 Antibody Tests and Their Application for Monitoring of Seroconversion and Stability of Antiviral Antibody Response in Healthcare Workers in Moscow
inferred← citeshttps://doi.org/10.3390/microorganisms11071789openalex-snapshot
A Severe Acute Respiratory Syndrome Coronavirus 2 Anti-Spike Immunoglobulin G Assay: A Robust Method for Evaluation of Vaccine Immunogenicity Using an Established Correlate of Protection
inferred← citeshttps://doi.org/10.3390/mps4030047openalex-snapshot
Sensitive and Specific Immunohistochemistry Protocol for Nucleocapsid Protein from All Common SARS-CoV-2 Virus Strains in Formalin-Fixed, Paraffin Embedded Tissues
inferred← citeshttps://doi.org/10.3390/s21175857openalex-snapshot
Monitoring Serum Spike Protein with Disposable Photonic Biosensors Following SARS-CoV-2 Vaccination
inferred← citeshttps://doi.org/10.3390/v13040697openalex-snapshot
Characteristics of Anti-SARS-CoV-2 Antibodies in Recovered COVID-19 Subjects
inferred← citeshttps://doi.org/10.3390/v13081579openalex-snapshot
Coronavirus Pseudotypes for All Circulating Human Coronaviruses for Quantification of Cross-Neutralizing Antibody Responses
inferred← citeshttps://doi.org/10.3390/v13112325openalex-snapshot
Cross-Reactive Antibodies to SARS-CoV-2 and MERS-CoV in Pre-COVID-19 Blood Samples from Sierra Leoneans
inferred← citeshttps://doi.org/10.3390/v13122391openalex-snapshot
The Role of Serology Testing in the Context of Immunization Policies for COVID-19 in Latin American Countries
inferred← citeshttps://doi.org/10.3390/v13122553openalex-snapshot
Microarray-Based Detection of Antibodies against SARS-CoV-2 Proteins, Common Respiratory Viruses and Type I Interferons
inferred← citeshttps://doi.org/10.3390/v14030562openalex-snapshot
A Novel Method to Reduce ELISA Serial Dilution Assay Workload Applied to SARS-CoV-2 and Seasonal HCoVs
inferred← citeshttps://doi.org/10.3390/v14051031openalex-snapshot
B-Cell-Epitope-Based Fluorescent Quantum Dot Biosensors for SARS-CoV-2 Enable Highly Sensitive COVID-19 Antibody Detection
inferred← citeshttps://doi.org/10.3390/v14071517openalex-snapshot
Distinct Antibody Responses to Endemic Coronaviruses Pre- and Post-SARS-CoV-2 Infection in Kenyan Infants and Mothers
inferred← citeshttps://doi.org/10.3390/v15010175openalex-snapshot
Risk Factors of Severe COVID-19: A Review of Host, Viral and Environmental Factors
inferred← citeshttps://doi.org/10.3390/v15020578openalex-snapshot
Human Coronavirus OC43 as a Low-Risk Model to Study COVID-19
inferred← citeshttps://doi.org/10.3390/v16030448openalex-snapshot
Viral Epitope Scanning Reveals Correlation between Seasonal HCoVs and SARS-CoV-2 Antibody Responses among Cancer and Non-Cancer Patients
inferred← citeshttps://doi.org/10.3390/v17060837openalex-snapshot
Serological Surveillance of Betacoronaviruses in Bat Guano Collectors: Pre-COVID-19 Pandemic and Post-SARS-CoV-2 Emergence
inferred← citeshttps://doi.org/10.3390/vaccines10060980openalex-snapshot
Broad Cross-Reactive IgA and IgG against Human Coronaviruses in Milk Induced by COVID-19 Vaccination and Infection
inferred← citeshttps://doi.org/10.3390/vaccines11010058openalex-snapshot
Analysis of Antibody Neutralisation Activity against SARS-CoV-2 Variants and Seasonal Human Coronaviruses NL63, HKU1, and 229E Induced by Three Different COVID-19 Vaccine Platforms
inferred← citeshttps://doi.org/10.3390/vaccines11010123openalex-snapshot
Refocus on Immunogenic Characteristics of Convalescent COVID-19 Challenged by Prototype SARS-CoV-2
inferred← citeshttps://doi.org/10.3390/vaccines13070761openalex-snapshot
Adaptation of the Vaccine Prophylaxis Strategy to Variants of the SARS-CoV-2 Virus
inferred← citeshttps://doi.org/10.3390/vaccines13111168openalex-snapshot
Current Status and Challenges of Vaccine Development for Seasonal Human Coronaviruses
inferred← citeshttps://doi.org/10.3390/vaccines14070604openalex-snapshot
Evaluating Memory B Cell Cross-Reactivity Between Ancestral and Future SARS-CoV-2 Variants—Evidence for Original Antigenic Sin
inferred← citeshttps://doi.org/10.4018/978-1-7998-4679-6.ch006openalex-snapshot
SARS-CoV-2 Is a Robot Bioweapon
inferred← citeshttps://doi.org/10.4155/bio-2020-0219openalex-snapshot
Key Points of Technical Review for the Registration of Sars-Cov-2 Antigen/Antibody Tests
inferred← citeshttps://doi.org/10.5114/ms.2023.131679openalex-snapshot
COVID-19 humoral response
inferred← citeshttps://doi.org/10.70675/00bd0a63z263fz470az876czb50b49ba4313openalex-snapshot
Caractérisation de la réponse lymphocytaire B mémoire contre le SARS-CoV-2 après infection ou vaccination
inferred← citeshttps://doi.org/10.7717/peerj.13721openalex-snapshot
Optimizing human coronavirus OC43 growth and titration
inferred← citeshttps://doi.org/10.7759/cureus.34096openalex-snapshot
False-Positive Human Immunodeficiency Virus Results in COVID-19 Patients
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