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A Prospective Study of Transsulfuration Biomarkers in Autistic Disorders

https://doi.org/10.1007/s11064-008-9782-x

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism

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Cysteine dioxygenase: Regional localisation of protein and mRNA in rat brain

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A systems neuroscience approach to autism: Biological, cognitive, and clinical perspectives

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Measurement of Sulfate Concentrations and Tracer/Tracee Ratios in Biological Fluids by Electrospray Tandem Mass Spectrometry

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Identification of a Mammalian Brain Sulfate Transporter

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Brief report: Ear infections in autistic and normal children

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Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS)

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The metabolism of homocysteine: pathways and regulation

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Mechanisms of heavy-metal sequestration and detoxification in crustaceans: a review

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Increased oxidative stress and altered activities of erythrocyte free radical scavenging enzymes in autism

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A rapid method for the determination of taurine in biological tissue

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Biliary secretion of glutathione and of glutathione-metal complexes*1

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Phenotypic variation in xenobiotic metabolism and adverse environmental response: focus on sulfur-dependent detoxification pathways

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Estradiol reduces cumulative mercury and associated disturbances in the hypothalamus–pituitary axis of ovariectomized rats

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Lowered DHEA-S plasma levels in adult individuals with autistic disorder

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Liquid chromatography–tandem mass spectrometry assay of reduced and oxidized glutathione and main precursors in mice liver

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Oxidative stress in autism: Increased lipid peroxidation and reduced serum levels of ceruloplasmin and transferrin - the antioxidant proteins

inferredcites →https://doi.org/10.1016/j.neuro.2006.03.017openalex-snapshot

Autism and environmental genomics

inferredcites →https://doi.org/10.1016/j.pediatrneurol.2005.03.014openalex-snapshot

Cerebrospinal Fluid and Serum Markers of Inflammation in Autism

inferredcites →https://doi.org/10.1016/s0006-3223(98)00337-0openalex-snapshot

Sulphation deficit in “low-functioning” autistic children: a pilot study

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Analysis of glutathione: implication in redox and detoxification

inferredcites →https://doi.org/10.1016/s0013-9351(87)80072-5openalex-snapshot

Sexual differences in the excretion of organic and inorganic mercury by methyl mercury-treated rats

inferredcites →https://doi.org/10.1016/s0891-5849(01)00480-4openalex-snapshot

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

inferredcites →https://doi.org/10.1016/s0891-5849(99)00176-8openalex-snapshot

Biologic and pharmacologic regulation of mammalian glutathione synthesis

inferredcites →https://doi.org/10.1023/a:1020734325815openalex-snapshot

The Relation Between General Cognitive Level and Adaptive Behavior Domains in Individuals with Autism with and Without Co-Morbid Mental Retardation

inferredcites →https://doi.org/10.1039/an9921700413openalex-snapshot

Indirect atomic absorption spectrometric determination of sulfate in human blood serum

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The role of glutathione in the regulation of apoptosis

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Regulation of protein function by S‐glutathiolation in response to oxidative and nitrosative stress

inferredcites →https://doi.org/10.1054/plef.2002.0439openalex-snapshot

Investigation of antioxidant enzymes in children with autistic disorder

inferredcites →https://doi.org/10.1055/s-2007-1007167openalex-snapshot

Role of the Liver in Interorgan Homeostasis of Glutathione and Cyst(e)ine

inferredcites →https://doi.org/10.1080/10715760290019354openalex-snapshot

Antioxidant and Pro-oxidant Effect of the Thiolic Compounds N -acetyl- l -cysteine and Glutathione against Free Radical-induced Lipid Peroxidation

inferredcites →https://doi.org/10.1080/10937400600882079openalex-snapshot

Evidence of Toxicity, Oxidative Stress, and Neuronal Insult in Autism

inferredcites →https://doi.org/10.1080/13590840050000861openalex-snapshot

Sulphur Metabolism in Autism

inferredcites →https://doi.org/10.1089/ars.2007.1712openalex-snapshot

Testosterone Regulation of Homocysteine Metabolism Modulates Redox Status in Human Prostate Cancer Cells

inferredcites →https://doi.org/10.1093/ajcn/80.6.1611openalex-snapshot

Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism

inferredcites →https://doi.org/10.1093/clinchem/32.8.1551openalex-snapshot

Urinary protein as measured with a pyrogallol red-molybdate complex, manually and in a Hitachi 726 automated analyzer.

inferredcites →https://doi.org/10.1097/00008480-200210000-00004openalex-snapshot

Autistic disorder and gastrointestinal disease

inferredcites →https://doi.org/10.1097/00075197-200201000-00015openalex-snapshot

Redox control of the transsulfuration and glutathione biosynthesis pathways

inferredcites →https://doi.org/10.1111/j.1749-6632.2002.tb04690.xopenalex-snapshot

Glutathione in Defense and Signaling

inferredcites →https://doi.org/10.1159/000084164openalex-snapshot

Dysregulated Innate Immune Responses in Young Children with Autism Spectrum Disorders: Their Relationship to Gastrointestinal Symptoms and Dietary Intervention

inferredcites →https://doi.org/10.1159/000094467openalex-snapshot

A Clinical and Laboratory Evaluation of Methionine Cycle-Transsulfuration and Androgen Pathway Markers in Children with Autistic Disorders

inferredcites →https://doi.org/10.1177/153537020322800601openalex-snapshot

Intestinal Pathophysiology in Autism

inferredcites →https://doi.org/10.1289/ehp.00108s3511openalex-snapshot

Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.

inferredcites →https://doi.org/10.1373/clinchem.2004.032920openalex-snapshot

Homogeneous Enzymatic Colorimetric Assay for Total Cysteine

inferredcites →https://doi.org/10.1515/bc.2003.061openalex-snapshot

Cytoprotection against Oxidative Stress and the Regulation of Glutathione Synthesis

inferredcites →https://doi.org/10.1542/peds.112.5.e420openalex-snapshot

Increased Prevalence of Familial Autoimmunity in Probands With Pervasive Developmental Disorders

inferredcites →https://doi.org/10.5271/sjweh.2239openalex-snapshot

Reproductive and developmental toxicity of metals.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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An Investigation of the Dynamic Thiol/Disulfide Homeostasis, As a Novel Oxidative Stress Plasma Biomarker, in Children With Autism Spectrum Disorders

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Chromatographic methods in the study of autism

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Cysteine and homocysteine as biomarker of various diseases

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Redox/Methylation Theory and Autism

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Contribution of Oxidative Stress to the Pathophysiology of Autism Spectrum Disorders: Impact of Genetic and Environmental Factors

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Increased Vulnerability to Oxidative Stress and Mitochondrial Dysfunction in Autism

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Current Therapies

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Is Taurine a Biomarker in Autistic Spectrum Disorder?

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Oxidative Stress in Psychiatric Disorders

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Taurine Partially Improves Abnormal Anxiety in Taurine-Deficient Mice

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Honey: A Powerful Natural Antioxidant and Its Possible Mechanism of Action

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Plasma Amino Acid Profile in Children with Autism Spectrum Disorder in Southern China: Analysis of 110 Cases

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Brain Region-Specific Glutathione Redox Imbalance in Autism

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Chromium, Cadmium, and Lead Levels in Urine of Children with Autism and Typically Developing Controls

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Altered Heavy Metals and Transketolase Found in Autistic Spectrum Disorder

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Diagnostic and Severity-Tracking Biomarkers for Autism Spectrum Disorder

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Heparan sulfate deficiency in autistic postmortem brain tissue from the subventricular zone of the lateral ventricles

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Postnatal N-acetylcysteine administration rescues impaired social behaviors and neurogenesis in Slc13a4 haploinsufficient mice

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VLDL-specific increases of fatty acids in autism spectrum disorder correlate with social interaction

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Toxic metal(loid)-based pollutants and their possible role in autism spectrum disorder

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Perineuronal net abnormalities in Slc13a4 mice are rescued by postnatal administration of N-acetylcysteine

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Chronic exposure to xenobiotic pollution leads to significantly higher total glutathione and lower reduced to oxidized glutathione ratio in red blood cells of children with autism

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Similarities in features of autism and asthma and a possible link to acetaminophen use

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Might cholesterol sulfate deficiency contribute to the development of autistic spectrum disorder?

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Reduced sulfate plasma concentrations in the BTBR T+tf/J mouse model of autism

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Early pyridoxine administration rescues autism-like behavior in the BTBR T+tf/J autistic model

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Biochemical screening and PTEN mutation analysis in individuals with autism spectrum disorders and macrocephaly

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Dietary glycemic index modulates the behavioral and biochemical abnormalities associated with autism spectrum disorder

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Charting unknown metabolic reactions by mass spectrometry-resolved stable-isotope tracing metabolomics

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Bioactivity Focus of α-Cyano-4-hydroxycinnamic acid (CHCA) Leads to Effective Multifunctional Aldose Reductase Inhibitors

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Bioactive Egg Proteins

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Autism

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Current World Literature

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The Gut Microbiota and Oxidative Stress in Autism Spectrum Disorders (ASD)

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Detoxification mechanisms in autism spectrum disorders

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Advances in Causes and Treatment of Autism

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Influence of diet on autism

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Altered Metabolites in the Plasma of Autism Spectrum Disorder: A Capillary Electrophoresis Time-of-Flight Mass Spectroscopy Study

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Excitation/inhibition imbalance and impaired neurogenesis in neurodevelopmental and neurodegenerative disorders

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Autism: an emerging ‘neuroimmune disorder’ in search of therapy

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Autism spectrum disorder-associated biomarkers for case evaluation and management by clinical geneticists

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Coumarins as Antioxidants

inferred← citeshttps://doi.org/10.2174/092986712802002572openalex-snapshot

Glutathione-Related Factors and Oxidative Stress in Autism, A Review

inferred← citeshttps://doi.org/10.2174/1570159x11666131120223757openalex-snapshot

Redox Regulation and the Autistic Spectrum: Role of Tryptophan Catabolites, Immuno-inflammation, Autoimmunity and the Amygdala

inferred← citeshttps://doi.org/10.22159/ajpcr.2025v18i11.56537openalex-snapshot

POLYPHENOLIC PROFILING BY LC–ESI–MS/MS AND BIOLOGICAL ACTIVITY ASSESSMENT OF LATHYRUS OCHRUS EXTRACTS

inferred← citeshttps://doi.org/10.2217/bmm.13.158openalex-snapshot

Metabolic Pathology of Autism in Relation to Redox Metabolism

inferred← citeshttps://doi.org/10.2217/pgs.10.157openalex-snapshot

Pharmacometabonomics as an Effector for Personalized Medicine

inferred← citeshttps://doi.org/10.2217/phe.09.5openalex-snapshot

Preventable Cases of Autism: Relationship Between Chronic Infectious Diseases and Neurological Outcome

inferred← citeshttps://doi.org/10.2741/730openalex-snapshot

The role of trace elements thiamin e and transketolase in autism and autistic spectrum disorder

inferred← citeshttps://doi.org/10.2741/e730openalex-snapshot

The role of trace elements thiamin e in autism and autistic spectrum disorder

inferred← citeshttps://doi.org/10.3233/jpb-120067openalex-snapshot

Folate receptor alpha autoimmunity and cerebral folate deficiency in autism spectrum disorders

inferred← citeshttps://doi.org/10.32628/ijsrst229648openalex-snapshot

Phytochemical Screening and Comparative Study of Antioxidant Activity of Different Parts of Mulberry Plant

inferred← citeshttps://doi.org/10.33448/rsd-v10i10.18924openalex-snapshot

Biomarcadores plasmáticos e salivares para diagnóstico precoce de Transtorno do Espectro Autista: revisão sistemática

inferred← citeshttps://doi.org/10.3345/cep.2022.01319openalex-snapshot

Acetaminophen causes neurodevelopmental injury in susceptible babies and children: no valid rationale for controversy

inferred← citeshttps://doi.org/10.3389/fcimb.2025.1601888openalex-snapshot

Neurodevelopmental disorders and gut-brain interactions: exploring the therapeutic potential of pycnogenol through microbial-metabolic-neural networks

inferred← citeshttps://doi.org/10.3389/fpsyt.2021.657105openalex-snapshot

Comparison of the Metabolic Profiles in the Plasma and Urine Samples Between Autistic and Typically Developing Boys: A Preliminary Study

inferred← citeshttps://doi.org/10.3389/fpsyt.2021.669089openalex-snapshot

Improving Antioxidant Capacity in Children With Autism: A Randomized, Double-Blind Controlled Study With Cysteine-Rich Whey Protein

inferred← citeshttps://doi.org/10.3389/fpsyt.2025.1700059openalex-snapshot

Association between decreased taurine levels in the anterior cingulate cortex and restricted and repetitive behaviors in autism spectrum disorder: a cross-sectional study

inferred← citeshttps://doi.org/10.3389/fpubh.2013.00031openalex-snapshot

A review of traditional and novel treatments for seizures in autism spectrum disorder: findings from a systematic review and expert panel

inferred← citeshttps://doi.org/10.3390/antiox9121186openalex-snapshot

Natural Antioxidants: A Novel Therapeutic Approach to Autism Spectrum Disorders?

inferred← citeshttps://doi.org/10.3390/bs10010026openalex-snapshot

Postnatal Acetaminophen and Potential Risk of Autism Spectrum Disorder among Males

inferred← citeshttps://doi.org/10.3390/cells13231968openalex-snapshot

Neurodevelopment of Autism: Critical Periods, Stress and Nutrition

inferred← citeshttps://doi.org/10.3390/e14101953openalex-snapshot

Impaired Sulfate Metabolism and Epigenetics: Is There a Link in Autism?

inferred← citeshttps://doi.org/10.3390/e14112227openalex-snapshot

Empirical Data Confirm Autism Symptoms Related to Aluminum and Acetaminophen Exposure

inferred← citeshttps://doi.org/10.3390/ijerph10083771openalex-snapshot

Thimerosal Exposure and the Role of Sulfation Chemistry and Thiol Availability in Autism

inferred← citeshttps://doi.org/10.3390/ijerph18041377openalex-snapshot

Associations of Metabolic Genes (GSTT1, GSTP1, GSTM1) and Blood Mercury Concentrations Differ in Jamaican Children with and without Autism Spectrum Disorder

inferred← citeshttps://doi.org/10.3390/ijms24065487openalex-snapshot

Neuroinflammation and Oxidative Stress in the Pathogenesis of Autism Spectrum Disorder

inferred← citeshttps://doi.org/10.3390/ijms26041513openalex-snapshot

Review of Elevated Para-Cresol in Autism and Possible Impact on Symptoms

inferred← citeshttps://doi.org/10.3390/life14080918openalex-snapshot

Evaluating the Role of Susceptibility Inducing Cofactors and of Acetaminophen in the Etiology of Autism Spectrum Disorder

inferred← citeshttps://doi.org/10.3390/metabo16070461openalex-snapshot

Sulfur-Containing Amino Acid Homeostasis in the Central Nervous System: From Physiology Regulation to Metal-Induced Neurotoxicity

inferred← citeshttps://doi.org/10.3390/molecules27217174openalex-snapshot

Repurposing SGLT2 Inhibitors for Neurological Disorders: A Focus on the Autism Spectrum Disorder

inferred← citeshttps://doi.org/10.3390/nu10030369openalex-snapshot

Comprehensive Nutritional and Dietary Intervention for Autism Spectrum Disorder—A Randomized, Controlled 12-Month Trial

inferred← citeshttps://doi.org/10.3390/nu14102035openalex-snapshot

Improvement of the Clinical and Psychological Profile of Patients with Autism after Methylcobalamin Syrup Administration

inferred← citeshttps://doi.org/10.3945/an.114.007914openalex-snapshot

Nutritional Status of Individuals with Autism Spectrum Disorders: Do We Know Enough?

inferred← citeshttps://doi.org/10.4103/ijnpnd.ijnpnd_100_20openalex-snapshot

Cardioprotective Effects of Gallic Acid on an Isoprenaline-Induced Myocardial Infarction Rat Model

inferred← citeshttps://doi.org/10.4103/sni.sni_407_17openalex-snapshot

Immunoexcitotoxicity as the central mechanism of etiopathology and treatment of autism spectrum disorders: A possible role of fluoride and aluminum

inferred← citeshttps://doi.org/10.4137/ijtr.s11355openalex-snapshot

Role of NAD + , Oxidative Stress, and Tryptophan Metabolism in Autism Spectrum Disorders

inferred← citeshttps://doi.org/10.4172/2167-0501.1000159openalex-snapshot

Sulfur Metabolism and Sulfur-Containing Amino Acids Derivatives – II: Autism Spectrum Disorders, Schizophrenia and Fibromyalgia

inferred← citeshttps://doi.org/10.4172/psychiatry.1000179openalex-snapshot

Evaluation of MTHFR Genetic Polymorphism as a Risk Factor in Egyptian Autistic Children and Mothers

inferred← citeshttps://doi.org/10.4322/mp.978-65-84548-17-6.c1openalex-snapshot

Compostos Bioativos nos Transtornos do Espectro Autista: Revisão de Literatura

inferred← citeshttps://doi.org/10.48175/ijarsct-2649openalex-snapshot

An Overview on Antioxidants

inferred← citeshttps://doi.org/10.5530/fra.2024.2.7openalex-snapshot

Antioxidants, Radical Scavengers, and Their Impact on Oxidative Stress

inferred← citeshttps://doi.org/10.55782/ane-2010-1789openalex-snapshot

Blood mercury levels in autism spectrum disorder: is there a threshold level?

inferred← citeshttps://doi.org/10.55782/ane-2010-1792openalex-snapshot

The biological basis of autism spectrum disorders: Understanding causation and treatment by clinical geneticists

inferred← citeshttps://doi.org/10.55782/ane-2012-1887openalex-snapshot

Evidence of parallels between mercury intoxication and the brain pathology in autism

inferred← citeshttps://doi.org/10.5772/18571openalex-snapshot

The Biochemical Basis of Autistic Behavior and Pathology

inferred← citeshttps://doi.org/10.5772/974openalex-snapshot

Autism - A Neurodevelopmental Journey from Genes to Behaviour

inferred← citeshttps://doi.org/10.70675/748809c3z8827z45abzaf47z18190a5bc6a7openalex-snapshot

Caractérisation du long ARN non codant COSMOC dérégulé dans les troubles du spectre autistique : une approche transcriptomique sur cellules souches olfactives humaines

inferred← citeshttps://doi.org/10.70675/e85baa14za470z42efz9c22z80d16e6155bfopenalex-snapshot

Étude génétique de la voie sérotonine-N-acétylsérotonine-mélatonine et de ses anomalies dans la vulnérabilité aux Troubles du Spectre Autistique (TSA) et dans la prématurité

inferred← citeshttps://doi.org/10.7790/ejap.v5i1.141openalex-snapshot

A Prospective Study of Oxidative Stress Biomarkers in Autistic Disorders

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