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Drug Targeting to the Brain

https://doi.org/10.1007/s11095-007-9324-2

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Adeno-associated viral vector-mediated gene transfer of brain-derived neurotrophic factor reverses atrophy of rubrospinal neurons following both acute and chronic spinal cord injury

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Expression of various multidrug resistance-associated protein (MRP) homologues in brain microvessel endothelial cells

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Conjugation of brain-derived neurotrophic factor to a blood–brain barrier drug targeting system enables neuroprotection in regional brain ischemia following intravenous injection of the neurotrophin

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Functional heterodimeric amino acid transporters lacking cysteine residues involved in disulfide bond

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Selective transport of an anti-transferrin receptor antibody through the blood-brain barrier in vivo.

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Transport through the Ependymal Linings

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Drug delivery to damaged brain

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Mediated efflux of IgG molecules from brain to blood across the blood–brain barrier

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1

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Carrier-mediated or specialized transport of drugs across the blood–brain barrier

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The blood–brain barrier efflux transporters as a detoxifying system for the brain

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Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain

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Drug-like properties and the causes of poor solubility and poor permeability

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inferredcites →https://doi.org/10.1017/cbo9780511549571openalex-snapshot

Brain Drug Targeting

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Transport Across the Primate Blood-Brain Barrier of a Genetically Engineered Chimeric Monoclonal Antibody to the Human Insulin Receptor

inferredcites →https://doi.org/10.1023/a:1010910523202openalex-snapshot

Receptor-Mediated Gene Targeting to Tissues In Vivo Following Intravenous Administration of Pegylated Immunoliposomes

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Carboxyl-directed Pegylation of Brain-derived Neurotrophic Factor Markedly Reduces Systemic Clearance with Minimal Loss of Biologic Activity

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Chemotherapeutic Drugs Released from Polymers: Distribution of 1,3-bis(2-chloroethyl)-l-nitrosourea in the Rat Brain

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Human Insulin Receptor Monoclonal Antibody Undergoes High Affinity Binding to Human Brain Capillaries in Vitro and Rapid Transcytosis Through the Blood–Brain Barrier in Vivo in the Primate

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Autophagy: Many paths to the same end

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Absence of Toxicity of Chronic Weekly Intravenous Gene Therapy with Pegylated Immunoliposomes

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Diffusion of Small Non-Electrolytes across Liposome Membranes

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Astrocytes induce blood–brain barrier properties in endothelial cells

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Regulated portals of entry into the cell

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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

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Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

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Drug and gene targeting to the brain with molecular trojan horses

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Drug resistance in brain diseases and the role of drug efflux transporters

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Alkylglycerol opening of the blood–brain barrier to small and large fluorescence markers in normal and C6 glioma‐bearing rats and isolated rat brain capillaries

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Liposome-mediated, nonviral gene transfer induces a systemic inflammatory response which can exacerbate pre-existing inflammation

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Immunity to adenovirus and adeno-associated viral vectors: implications for gene therapy

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Brain Endothelial Hemostasis Regulation by Pericytes

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Transgenic mice expressing the diphtheria toxin receptor are sensitive to the toxin

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Rapid transferrin efflux from brain to blood across the blood–brain barrier

inferredcites →https://doi.org/10.1046/j.1471-4159.2001.00541.xopenalex-snapshot

Restricted transport of anti‐transferrin receptor antibody (OX26) through the blood–brain barrier in the rat

inferredcites →https://doi.org/10.1046/j.1471-4159.2002.00840.xopenalex-snapshot

Expression of the neonatal Fc receptor (FcRn) at the blood–brain barrier

inferredcites →https://doi.org/10.1046/j.1471-4159.2002.01201.xopenalex-snapshot

High transcytosis of melanotransferrin (P97) across the blood–brain barrier

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Site‐directed mutagenesis of rabbit LAT1 at amino acids 219 and 234

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Overcoming the blood-brain barrier with high-dose enzyme replacement therapy in murine mucopolysaccharidosis VII

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Gene transfer of human acid sphingomyelinase corrects neuropathology and motor deficits in a mouse model of Niemann-Pick type A disease

inferredcites →https://doi.org/10.1073/pnas.130187497openalex-snapshot

Noninvasive gene targeting to the brain

inferredcites →https://doi.org/10.1073/pnas.201415498openalex-snapshot

Delivery of the Cre recombinase by a self-deleting lentiviral vector: Efficient gene targeting in vivo

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Brain-specific expression of an exogenous gene after i.v. administration

inferredcites →https://doi.org/10.1073/pnas.73.9.3197openalex-snapshot

Localization of vasoactive intestinal polypeptide (VIP) to central and peripheral neurons.

inferredcites →https://doi.org/10.1073/pnas.79.13.4185openalex-snapshot

Pharmacokinetics of progesterone after its administration to ovariectomized rhesus monkeys by injection, infusion, or nasal spraying.

inferredcites →https://doi.org/10.1073/pnas.80.8.2400openalex-snapshot

Cholecystokinin-immunoreactive neurons in rat and monkey cerebral cortex make symmetric synapses and have intimate associations with blood vessels.

inferredcites →https://doi.org/10.1073/pnas.86.2.695openalex-snapshot

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

inferredcites →https://doi.org/10.1073/pnas.92.12.5592openalex-snapshot

Vector-mediated delivery of a polyamide ("peptide") nucleic acid analogue through the blood-brain barrier in vivo.

inferredcites →https://doi.org/10.1073/pnas.92.22.10227openalex-snapshot

Vector-mediated delivery of 125I-labeled beta-amyloid peptide A beta 1-40 through the blood-brain barrier and binding to Alzheimer disease amyloid of the A beta 1-40/vector complex.

inferredcites →https://doi.org/10.1073/pnas.93.9.4229openalex-snapshot

Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers.

inferredcites →https://doi.org/10.1073/pnas.96.1.254openalex-snapshot

Neuroprotection with noninvasive neurotrophin delivery to the brain

inferredcites →https://doi.org/10.1073/pnas.97.24.13003openalex-snapshot

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters

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Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)

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Multifaceted Activities of the HIV-1 Transactivator of Transcription, Tat

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The Role of Organ Vascularization and Lipoplex-Serum Initial Contact in Intravenous Murine Lipofection

inferredcites →https://doi.org/10.1080/10611860400015936openalex-snapshot

Nanoparticle Surface Charges Alter Blood–Brain Barrier Integrity and Permeability

inferredcites →https://doi.org/10.1081/lpr-200064961openalex-snapshot

Cell-Specific Targeting of Lipid-Based Carriers for ODN and DNA

inferredcites →https://doi.org/10.1083/jcb.138.4.877openalex-snapshot

A New Function for the LDL Receptor: Transcytosis of LDL across the Blood–Brain Barrier

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FINE STRUCTURAL LOCALIZATION OF A BLOOD-BRAIN BARRIER TO EXOGENOUS PEROXIDASE

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JUNCTIONS BETWEEN INTIMATELY APPOSED CELL MEMBRANES IN THE VERTEBRATE BRAIN

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Immune Protection of the Brain—Efficient and Delicate

inferredcites →https://doi.org/10.1089/10430340050083243openalex-snapshot

Triple Transduction with Adeno-Associated Virus Vectors Expressing Tyrosine Hydroxylase, Aromatic-L-Amino-Acid Decarboxylase, and GTP Cyclohydrolase I for Gene Therapy of Parkinson's Disease

inferredcites →https://doi.org/10.1089/10430340252837198openalex-snapshot

Critical Issues in Gene Therapy for Neurologic Disease

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Recombinant Adeno-Associated Viral Vectors in the Nervous System

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A randomized, double-blind, placebo-controlled, phase 2 study of RMP-7 in combination with carboplatin administered intravenously for the treatment of recurrent malignant glioma

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inferred← citeshttps://doi.org/10.1016/b978-0-443-13286-5.00006-5openalex-snapshot

Modeling thermal therapy of poroelastic brain tumor using magnetic nanoparticles

inferred← citeshttps://doi.org/10.1016/b978-0-443-13474-6.00009-3openalex-snapshot

Novel drug delivery systems in cerebral vascular disorders, transient ischaemic attack, and stroke interventions

inferred← citeshttps://doi.org/10.1016/b978-0-443-13474-6.00017-2openalex-snapshot

Prodrug approaches for delivering CNS active agents

inferred← citeshttps://doi.org/10.1016/bs.apha.2014.06.005openalex-snapshot

Engineering and Pharmacology of Blood–Brain Barrier-Permeable Bispecific Antibodies

inferred← citeshttps://doi.org/10.1016/bs.irn.2016.06.007openalex-snapshot

Metal Nanoparticles as Targeted Carriers Circumventing the Blood–Brain Barrier

inferred← citeshttps://doi.org/10.1016/j.aca.2018.08.025openalex-snapshot

Label-free cytosensing of cancer cells based on the interaction between protein and an electron-transfer carbohydrate-mimetic peptide

inferred← citeshttps://doi.org/10.1016/j.actbio.2013.11.003openalex-snapshot

Study and evaluation of mechanisms of dual targeting drug delivery system with tumor microenvironment assays compared with normal assays

inferred← citeshttps://doi.org/10.1016/j.actbio.2015.05.009openalex-snapshot

Nanoparticles of alkylglyceryl-dextran-graft-poly(lactic acid) for drug delivery to the brain: Preparation and in vitro investigation

inferred← citeshttps://doi.org/10.1016/j.actbio.2021.04.005openalex-snapshot

Ultrasound-responsive nutlin-loaded nanoparticles for combined chemotherapy and piezoelectric treatment of glioblastoma cells

inferred← citeshttps://doi.org/10.1016/j.addr.2014.01.008openalex-snapshot

Ultrasound-mediated blood–brain barrier disruption for targeted drug delivery in the central nervous system

inferred← citeshttps://doi.org/10.1016/j.addr.2016.06.009openalex-snapshot

Poly(lactic acid) for delivery of bioactive macromolecules

inferred← citeshttps://doi.org/10.1016/j.addr.2018.04.006openalex-snapshot

Nucleic acids delivering nucleic acids

inferred← citeshttps://doi.org/10.1016/j.antiviral.2007.12.007openalex-snapshot

Highly pathogenic RNA viral infections: Challenges for antiviral research

inferred← citeshttps://doi.org/10.1016/j.apsb.2014.03.001openalex-snapshot

Brain tumor-targeted drug delivery strategies

inferred← citeshttps://doi.org/10.1016/j.apsb.2016.05.013openalex-snapshot

Progress and perspectives on targeting nanoparticles for brain drug delivery

inferred← citeshttps://doi.org/10.1016/j.apsb.2025.10.016openalex-snapshot

Pathology-directed drug delivery strategies: How to overcome blood–brain barrier for the treatment of brain diseases

inferred← citeshttps://doi.org/10.1016/j.arr.2024.102291openalex-snapshot

Treating Alzheimer’s disease using nanoparticle-mediated drug delivery strategies/systems

inferred← citeshttps://doi.org/10.1016/j.bbadis.2015.06.019openalex-snapshot

The emerging role of adiponectin in cerebrovascular and neurodegenerative diseases

inferred← citeshttps://doi.org/10.1016/j.bbamem.2016.07.002openalex-snapshot

Blood-brain barrier penetration of an Aβ-targeted, arginine-rich, d -enantiomeric peptide

inferred← citeshttps://doi.org/10.1016/j.bbapap.2009.10.018openalex-snapshot

Deregulated signalling networks in human brain tumours

inferred← citeshttps://doi.org/10.1016/j.bbrc.2021.02.138openalex-snapshot

Angiopep-2-modified calcium arsenite-loaded liposomes for targeted and pH-responsive delivery for anti-glioma therapy

inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152077openalex-snapshot

Identification of indirect pathways enhancing the biocompatibility of DOX/GO/Fe3O4 nanomaterials in Glioblastoma: Gene network modeling and pathway analysis

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2009.11.020openalex-snapshot

The utilization of pathogen-like cellular trafficking by single chain block copolymer

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2010.06.053openalex-snapshot

Transferrin-conjugated nanoparticles of Poly(lactide)-d-α-Tocopheryl polyethylene glycol succinate diblock copolymer for targeted drug delivery across the blood–brain barrier

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2010.09.002openalex-snapshot

PEGylated Poly(amidoamine) dendrimer-based dual-targeting carrier for treating brain tumors

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2012.03.058openalex-snapshot

Precise glioma targeting of and penetration by aptamer and peptide dual-functioned nanoparticles

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2012.07.046openalex-snapshot

Anti-glioblastoma efficacy and safety of paclitaxel-loading Angiopep-conjugated dual targeting PEG-PCL nanoparticles

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2013.10.064openalex-snapshot

Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2014.03.068openalex-snapshot

Nanoparticles functionalized with Pep-1 as potential glioma targeting delivery system via interleukin 13 receptor α2-mediated endocytosis

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2020.120492openalex-snapshot

Advances in nanomedicines for diagnosis of central nervous system disorders

inferred← citeshttps://doi.org/10.1016/j.biopha.2025.117863openalex-snapshot

LM22A-4-loaded smart mesoporous balls enhance neuroprotection and functional recovery after ischemic stroke

inferred← citeshttps://doi.org/10.1016/j.bmcl.2015.03.002openalex-snapshot

Pharmacokinetic, pharmacodynamic and metabolic characterization of a brain retentive microtubule (MT)-stabilizing triazolopyrimidine

inferred← citeshttps://doi.org/10.1016/j.brainres.2008.07.121openalex-snapshot

VEGF increases blood–brain barrier permeability to Evans blue dye and tetanus toxin fragment C but not adeno-associated virus in ALS mice

inferred← citeshttps://doi.org/10.1016/j.brainres.2010.08.044openalex-snapshot

Epidermal growth factor targeting of bacteriophage to the choroid plexus for gene delivery to the central nervous system via cerebrospinal fluid

inferred← citeshttps://doi.org/10.1016/j.brainres.2025.149590openalex-snapshot

Advancing Alzheimer’s disease therapy through engineered exosomal Macromolecules

inferred← citeshttps://doi.org/10.1016/j.cbi.2015.02.019openalex-snapshot

Inhibition of RNA transportation induces glioma cell apoptosis via downregulation of RanGAP1 expression

inferred← citeshttps://doi.org/10.1016/j.ccr.2024.215926openalex-snapshot

Brain-specific targeted delivery of therapeutic agents using metal–organic framework-based nanomedicine

inferred← citeshttps://doi.org/10.1016/j.cmpb.2023.107546openalex-snapshot

A prediction model for magnetic particle imaging–based magnetic hyperthermia applied to a brain tumor model

inferred← citeshttps://doi.org/10.1016/j.drudis.2014.06.004openalex-snapshot

Multidrug resistance in cancer or inefficacy of neuroactive agents: innovative strategies to inhibit or circumvent the active efflux transporters selectively

inferred← citeshttps://doi.org/10.1016/j.drudis.2020.01.007openalex-snapshot

Novel approaches for the delivery of therapeutics in ischemic stroke

inferred← citeshttps://doi.org/10.1016/j.ejpb.2010.11.015openalex-snapshot

Uptake and permeability studies of BBB-targeting immunoliposomes using the hCMEC/D3 cell line

inferred← citeshttps://doi.org/10.1016/j.ejpb.2013.06.005openalex-snapshot

Delivery of analgesic peptides to the brain by nano-sized bolaamphiphilic vesicles made of monolayer membranes

inferred← citeshttps://doi.org/10.1016/j.ejphar.2008.01.050openalex-snapshot

Brain insulin, energy and glucose homeostasis; genes, environment and metabolic pathologies

inferred← citeshttps://doi.org/10.1016/j.ejps.2010.03.007openalex-snapshot

Lactoferrin-modified procationic liposomes as a novel drug carrier for brain delivery

inferred← citeshttps://doi.org/10.1016/j.ejps.2011.11.015openalex-snapshot

Attaching the phage display-selected GLA peptide to liposomes: Factors influencing target binding

inferred← citeshttps://doi.org/10.1016/j.ejps.2012.04.011openalex-snapshot

In vitro & in vivo targeting behaviors of biotinylated Pluronic F127/poly(lactic acid) nanoparticles through biotin–avidin interaction

inferred← citeshttps://doi.org/10.1016/j.ejps.2013.05.027openalex-snapshot

Study of the transcytosis of an anti-transferrin receptor antibody with a Fab′ cargo across the blood–brain barrier in mice

inferred← citeshttps://doi.org/10.1016/j.ejps.2017.02.032openalex-snapshot

Nose-to-brain transport of imatinib mesylate: A pharmacokinetic evaluation

inferred← citeshttps://doi.org/10.1016/j.ejps.2017.04.019openalex-snapshot

Predictors for drug effects with brain disease: Shed new light from EEG parameters to brain connectomics

inferred← citeshttps://doi.org/10.1016/j.ijpharm.2009.05.009openalex-snapshot

The transnasal delivery of 5-fluorouracil to the rat brain is enhanced by acetazolamide (the inhibitor of the secretion of cerebrospinal fluid)

inferred← citeshttps://doi.org/10.1016/j.ijpharm.2010.05.017openalex-snapshot

Uptake and intracellular release kinetics of liposome formulations in glioma cells

inferred← citeshttps://doi.org/10.1016/j.ijpharm.2016.10.031openalex-snapshot

Nanomedicine as a non-invasive strategy for drug delivery across the blood brain barrier

inferred← citeshttps://doi.org/10.1016/j.ijpharm.2017.08.073openalex-snapshot

Peptide modified mesenchymal stem cells as targeting delivery system transfected with miR-133b for the treatment of cerebral ischemia

inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.120881openalex-snapshot

Design, optimization and pharmacokinetic evaluation of Piribedil loaded solid lipid nanoparticles dispersed in nasal in situ gelling system for effective management of Parkinson’s disease

inferred← citeshttps://doi.org/10.1016/j.isci.2023.108132openalex-snapshot

Exit pathways of therapeutic antibodies from the brain and retention strategies

inferred← citeshttps://doi.org/10.1016/j.jcis.2016.12.004openalex-snapshot

Precise glioblastoma targeting by AS1411 aptamer-functionalized poly (l-γ-glutamylglutamine)–paclitaxel nanoconjugates

inferred← citeshttps://doi.org/10.1016/j.jconrel.2008.08.017openalex-snapshot

Delivery of serotonin to the brain by monocytes following phagocytosis of liposomes

inferred← citeshttps://doi.org/10.1016/j.jconrel.2008.10.016openalex-snapshot

Lactoferrin-conjugated PEG–PLA nanoparticles with improved brain delivery: In vitro and in vivo evaluations

inferred← citeshttps://doi.org/10.1016/j.jconrel.2011.07.030openalex-snapshot

In vitro and in vivo efficacy of edelfosine-loaded lipid nanoparticles against glioma

inferred← citeshttps://doi.org/10.1016/j.jconrel.2011.12.042openalex-snapshot

Delivery of proteins to the brain by bolaamphiphilic nano-sized vesicles

inferred← citeshttps://doi.org/10.1016/j.jconrel.2012.01.031openalex-snapshot

Transferrin-conjugated polyphosphoester hybrid micelle loading paclitaxel for brain-targeting delivery: Synthesis, preparation and in vivo evaluation

inferred← citeshttps://doi.org/10.1016/j.jconrel.2012.05.052openalex-snapshot

Challenges in design and characterization of ligand-targeted drug delivery systems

inferred← citeshttps://doi.org/10.1016/j.jconrel.2013.06.028openalex-snapshot

Quantitative analysis of the brain-targeted delivery of drugs and model compounds using nano-delivery systems

inferred← citeshttps://doi.org/10.1016/j.jconrel.2014.06.006openalex-snapshot

Transferrin-bearing polypropylenimine dendrimer for targeted gene delivery to the brain

inferred← citeshttps://doi.org/10.1016/j.jconrel.2015.02.033openalex-snapshot

Multiple sessions of liposomal doxorubicin delivery via focused ultrasound mediated blood–brain barrier disruption: A safety study

inferred← citeshttps://doi.org/10.1016/j.jconrel.2015.09.003openalex-snapshot

Enhanced gene expression in the brain following intravenous administration of lactoferrin-bearing polypropylenimine dendriplex

inferred← citeshttps://doi.org/10.1016/j.jconrel.2016.05.044openalex-snapshot

Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases

inferred← citeshttps://doi.org/10.1016/j.jconrel.2018.03.025openalex-snapshot

Highly efficacious and specific anti-glioma chemotherapy by tandem nanomicelles co-functionalized with brain tumor-targeting and cell-penetrating peptides

inferred← citeshttps://doi.org/10.1016/j.jconrel.2020.05.020openalex-snapshot

Focused ultrasound for opening blood-brain barrier and drug delivery monitored with positron emission tomography

inferred← citeshttps://doi.org/10.1016/j.jconrel.2022.02.015openalex-snapshot

Recent advances in Bio-conjugated nanocarriers for crossing the Blood-Brain Barrier in (pre-)clinical studies with an emphasis on vesicles

inferred← citeshttps://doi.org/10.1016/j.jconrel.2024.02.020openalex-snapshot

Lipid-mediated protein corona regulation with increased apolipoprotein A-I recruitment for glioma targeting

inferred← citeshttps://doi.org/10.1016/j.jconrel.2025.113641openalex-snapshot

Lipid nanoparticle (LNP) mediated mRNA delivery in neurodegenerative diseases

inferred← citeshttps://doi.org/10.1016/j.jconrel.2026.114974openalex-snapshot

Dual ligand cooperation at the plasma membrane drives transport of engineered small extracellular vesicles across brain endothelial cells

inferred← citeshttps://doi.org/10.1016/j.jddst.2021.102414openalex-snapshot

Functionalized carbon nano onion as a novel drug delivery system for brain targeting

inferred← citeshttps://doi.org/10.1016/j.jddst.2022.103523openalex-snapshot

Efficacy of mimetic viral dynein binding peptide binding nanoparticles in blood-brain barrier model

inferred← citeshttps://doi.org/10.1016/j.jddst.2023.104970openalex-snapshot

Potential applications of mesoporous silica nanoparticles for the treatment of neurological disorders

inferred← citeshttps://doi.org/10.1016/j.jddst.2023.105160openalex-snapshot

Breaking barriers: Intranasal delivery of brexpiprazole-nanostructured lipid carriers targets the brain for effective schizophrenia treatment

inferred← citeshttps://doi.org/10.1016/j.jtice.2015.12.012openalex-snapshot

Delivery of doxorubicin to glioblastoma multiforme in vitro using solid lipid nanoparticles with surface aprotinin and melanotransferrin antibody for enhanced chemotherapy

inferred← citeshttps://doi.org/10.1016/j.jtice.2017.04.026openalex-snapshot

Anti-melanotransferrin and apolipoprotein E on doxorubicin-loaded cationic solid lipid nanoparticles for pharmacotherapy of glioblastoma multiforme

inferred← citeshttps://doi.org/10.1016/j.jtice.2017.05.003openalex-snapshot

Using catanionic solid lipid nanoparticles with wheat germ agglutinin and lactoferrin for targeted delivery of etoposide to glioblastoma multiforme

inferred← citeshttps://doi.org/10.1016/j.jtice.2018.03.001openalex-snapshot

Use of functionalized liposomes loaded with antioxidants to permeate the blood–brain barrier and inhibit β-amyloid-induced neurodegeneration in the brain

inferred← citeshttps://doi.org/10.1016/j.lfs.2016.01.025openalex-snapshot

Dual targeting of solid lipid nanoparticles grafted with 83-14 MAb and anti-EGF receptor for malignant brain tumor therapy

inferred← citeshttps://doi.org/10.1016/j.lfs.2021.119326openalex-snapshot

Targeting receptor-ligand chemistry for drug delivery across blood-brain barrier in brain diseases

inferred← citeshttps://doi.org/10.1016/j.matpr.2017.09.186openalex-snapshot

Characterisation and cellular uptake of polysorbate 80-coated PLA nanoparticles

inferred← citeshttps://doi.org/10.1016/j.matpr.2022.10.311openalex-snapshot

Nanotherapeutics a promising approach for treatment of Parkinson’s disease

inferred← citeshttps://doi.org/10.1016/j.medengphy.2022.103792openalex-snapshot

Computational modeling of poroelastic brain tumor therapy during heat transfer carrying temperature-dependent blood perfusion

inferred← citeshttps://doi.org/10.1016/j.msec.2017.03.309openalex-snapshot

Lactoferrin modified graphene oxide iron oxide nanocomposite for glioma-targeted drug delivery

inferred← citeshttps://doi.org/10.1016/j.msec.2018.05.062openalex-snapshot

Rosmarinic acid- and curcumin-loaded polyacrylamide-cardiolipin-poly(lactide-co-glycolide) nanoparticles with conjugated 83-14 monoclonal antibody to protect β-amyloid-insulted neurons

inferred← citeshttps://doi.org/10.1016/j.nano.2009.10.001openalex-snapshot

Tumor-associated macrophages are predominant carriers of cyclodextrin-based nanoparticles into gliomas

inferred← citeshttps://doi.org/10.1016/j.nano.2020.102149openalex-snapshot

Novel therapeutic strategies for Alzheimer's disease: Implications from cell-based therapy and nanotherapy

inferred← citeshttps://doi.org/10.1016/j.nano.2023.102673openalex-snapshot

Angiopep-2-conjugated FeTi@Au core-shell nanoparticles for tumor targeted dual-mode magnetic resonance imaging and hyperthermic glioma therapy

inferred← citeshttps://doi.org/10.1016/j.nbd.2009.02.009openalex-snapshot

A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease

inferred← citeshttps://doi.org/10.1016/j.nbd.2009.07.028openalex-snapshot

Approaches to transport therapeutic drugs across the blood–brain barrier to treat brain diseases

inferred← citeshttps://doi.org/10.1016/j.nbd.2015.07.008openalex-snapshot

Anti-Aβ antibodies incapable of reducing cerebral Aβ oligomers fail to attenuate spatial reference memory deficits in J20 mice

inferred← citeshttps://doi.org/10.1016/j.neuint.2012.05.019openalex-snapshot

The role of amino acid transporters in GSH synthesis in the blood–brain barrier and central nervous system

inferred← citeshttps://doi.org/10.1016/j.neuint.2015.08.011openalex-snapshot

Nano-antioxidants: An emerging strategy for intervention against neurodegenerative conditions

inferred← citeshttps://doi.org/10.1016/j.neuropharm.2016.03.014openalex-snapshot

Antibody therapies in CNS diseases

inferred← citeshttps://doi.org/10.1016/j.phymed.2010.03.009openalex-snapshot

Acetylcholinesterase inhibition in cognition-relevant brain areas of mice treated with a nootropic Amazonian herbal (Marapuama)

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2021.152543openalex-snapshot

Bioconcentration of neuroactive pharmaceuticals in fish: Relation to lipophilicity, experimental design and toxicity in the aquatic environment

inferred← citeshttps://doi.org/10.1016/j.tips.2009.01.005openalex-snapshot

Subcellular neuropharmacology: the importance of intracellular targeting

inferred← citeshttps://doi.org/10.1016/j.ultrasmedbio.2009.08.006openalex-snapshot

Molecules of Various Pharmacologically-Relevant Sizes Can Cross the Ultrasound-Induced Blood-Brain Barrier Opening in vivo

inferred← citeshttps://doi.org/10.1016/j.ultrasmedbio.2019.03.016openalex-snapshot

Influence of Nanobubble Concentration on Blood–Brain Barrier Opening Using Focused Ultrasound Under Real-Time Acoustic Feedback Control

inferred← citeshttps://doi.org/10.1016/j.ultrasmedbio.2020.04.013openalex-snapshot

Observed Effects of Whole-Brain Radiation Therapy on Focused Ultrasound Blood–Brain Barrier Disruption

inferred← citeshttps://doi.org/10.1016/j.vetpar.2011.05.028openalex-snapshot

Nanomedicine: Novel approaches in human and veterinary therapeutics

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