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Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection

https://doi.org/10.1007/s11684-020-0754-0
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Overview of lethal human coronaviruses
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Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations
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A pneumonia outbreak associated with a new coronavirus of probable bat origin
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Myocardial infarction increases ACE2 expression in rat and humans
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scRNA-seq assessment of the human lung, spleen, and esophagus tissue stability after cold preservation
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Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures
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Prognostic Factors for Severe Coronavirus Disease 2019 in Daegu, Korea

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Re: Khullar V, Lemmon B, Acar O, Abrams P, Vahabi B. Does COVID‐19 Cause or Worsen LUT Dysfunction, What Are the Mechanisms and Possible Treatments? ICI‐RS 2023 Neurourol Urodyn 2024 Aug; 43(6):1458–1463 doi: 101002/nau25441 Epub 2024 Mar 20 PMID: 38506116
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Re: Khullar V, Lemmon B, Acar O, Abrams P, Vahabi B Does COVID‐19 Cause or Worsen LUT Dysfunction, What Are the Mechanisms and Possible Treatments? ICI‐RS 2023. Neurourol Urodyn 2024 Aug;43(6):1458‐1463. doi: 101002/nau25441. Epub 2024 Mar 20. PMID: 38506116
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inferred← citeshttps://doi.org/10.1007/978-3-032-20428-8_5openalex-snapshot
Prediction of Drug Likeness and Synthetic Accessibility Using AI: A Case Study on Potential Therapeutic Compounds from Plants for SARS-CoV-2 Treatment
inferred← citeshttps://doi.org/10.1007/978-3-319-17002-2_98-1openalex-snapshot
Reproductive Effects of COVID-19: COVID Manifestations on the Endocrine and Reproductive Systems
inferred← citeshttps://doi.org/10.1007/978-981-16-5105-2_13openalex-snapshot
Insights Into the Role of Angiotensin-Converting Enzyme 2 in the Onset of Severe Acute Respiratory Syndrome Coronavirus 2 Pathogenesis
inferred← citeshttps://doi.org/10.1007/978-981-16-5105-2_23openalex-snapshot
Plausible Impacts of SARS-CoV-2 on Human Reproductive System
inferred← citeshttps://doi.org/10.1007/978-981-16-8957-4_14openalex-snapshot
SARS-CoV-2 and Microbiota
inferred← citeshttps://doi.org/10.1007/978-981-16-8957-4_15openalex-snapshot
Microbiome in SARS-CoV-2 (Covid-19)
inferred← citeshttps://doi.org/10.1007/978-981-33-6850-7_20openalex-snapshot
COVID-19 Pandemic Panic: Prophylactic as Well as Therapeutic Management with Traditional Ethnic Phytopharmaceuticals with Challenging Nano-spray Inhaler and Advanced Drug Delivery System
inferred← citeshttps://doi.org/10.1007/978-981-97-7380-0_7openalex-snapshot
Immunomodulator Activity of ACE Inhibitors and Angiotensin Receptor Blockers in Hypertensive Patients
inferred← citeshttps://doi.org/10.1007/978-981-99-3110-1_12openalex-snapshot
Molecular Diagnosis of Novel Coronavirus
inferred← citeshttps://doi.org/10.1007/s00011-020-01352-yopenalex-snapshot
SARS-CoV-2 will continue to circulate in the human population: an opinion from the point of view of the virus-host relationship
inferred← citeshttps://doi.org/10.1007/s00011-021-01487-6openalex-snapshot
SARS-CoV-2 and pathological matrix remodeling mediators
inferred← citeshttps://doi.org/10.1007/s00011-021-01510-wopenalex-snapshot
Gut microbiome, Vitamin D, ACE2 interactions are critical factors in immune-senescence and inflammaging: key for vaccine response and severity of COVID-19 infection
inferred← citeshttps://doi.org/10.1007/s00011-023-01723-1openalex-snapshot
Clinical manifestations of COVID-19 infection in dialysis patients and protective effect of COVID-19 vaccine
inferred← citeshttps://doi.org/10.1007/s00018-020-03611-xopenalex-snapshot
Advances in research on ACE2 as a receptor for 2019-nCoV
inferred← citeshttps://doi.org/10.1007/s00018-024-05520-9openalex-snapshot
Altered ACE2 and interferon landscape in the COVID-19 microenvironment correlate with the anti-PD-1 response in solid tumors
inferred← citeshttps://doi.org/10.1007/s00109-021-02175-yopenalex-snapshot
Purinergic signaling elements are correlated with coagulation players in peripheral blood and leukocyte samples from COVID-19 patients
inferred← citeshttps://doi.org/10.1007/s00109-024-02485-xopenalex-snapshot
Molecular mechanisms of thalidomide effectiveness on COVID-19 patients explained: ACE2 is a new ΔNp63α target gene
inferred← citeshttps://doi.org/10.1007/s00192-026-06765-7openalex-snapshot
Changes in Uropathogen Distribution in Relation to the COVID-19 Pandemic Timeline
inferred← citeshttps://doi.org/10.1007/s00210-020-01911-4openalex-snapshot
Vitamin D can prevent COVID-19 infection-induced multiple organ damage
inferred← citeshttps://doi.org/10.1007/s00221-021-06244-zopenalex-snapshot
Neurotropism of SARS-CoV-2 and neurological diseases of the central nervous system in COVID-19 patients
inferred← citeshttps://doi.org/10.1007/s00259-020-04780-4openalex-snapshot
Key elements of preparedness for pandemic coronavirus disease 2019 (COVID-19) in nuclear medicine units
inferred← citeshttps://doi.org/10.1007/s00261-020-02796-wopenalex-snapshot
Abdominal pelvic CT findings compared between COVID-19 positive and COVID-19 negative patients in the emergency department setting
inferred← citeshttps://doi.org/10.1007/s00296-021-04977-2openalex-snapshot
COVID-19 and fertility—at the crossroads of autoimmunity and thrombosis
inferred← citeshttps://doi.org/10.1007/s00330-020-07040-zopenalex-snapshot
Lung base CT findings in COVID-19 adult patients presenting with acute abdominal complaints: case series from a major New York City health system
inferred← citeshttps://doi.org/10.1007/s00345-020-03246-4openalex-snapshot
A systematic review on COVID-19: urological manifestations, viral RNA detection and special considerations in urological conditions
inferred← citeshttps://doi.org/10.1007/s00347-020-01150-1openalex-snapshot
Welche Bedeutung hat die Bindehaut als möglicher Übertragungsweg für eine SARS-CoV-2-Infektion?
inferred← citeshttps://doi.org/10.1007/s00347-020-01255-7openalex-snapshot
What is the significance of the conjunctiva as a potential transmission route for SARS-CoV-2 infections?
inferred← citeshttps://doi.org/10.1007/s00403-020-02156-0openalex-snapshot
Dermatological aspects of SARS-CoV-2 infection: mechanisms and manifestations
inferred← citeshttps://doi.org/10.1007/s00405-020-06155-9openalex-snapshot
Olfactory and gustatory abnormalities in COVID-19 cases
inferred← citeshttps://doi.org/10.1007/s00408-020-00408-4openalex-snapshot
ACE2: The Major Cell Entry Receptor for SARS-CoV-2
inferred← citeshttps://doi.org/10.1007/s00415-020-09929-7openalex-snapshot
Understanding the neurotropic characteristics of SARS-CoV-2: from neurological manifestations of COVID-19 to potential neurotropic mechanisms
inferred← citeshttps://doi.org/10.1007/s00417-020-04708-6openalex-snapshot
A child confirmed COVID-19 with only symptoms of conjunctivitis and eyelid dermatitis
inferred← citeshttps://doi.org/10.1007/s00418-022-02140-xopenalex-snapshot
Autoimmunity, cancer and COVID-19 abnormally activate wound healing pathways: critical role of inflammation
inferred← citeshttps://doi.org/10.1007/s00422-024-00989-wopenalex-snapshot
COVID-19 and silent hypoxemia in a minimal closed-loop model of the respiratory rhythm generator
inferred← citeshttps://doi.org/10.1007/s00432-021-03843-9openalex-snapshot
Expressions and significances of CTSL, the target of COVID‐19 on GBM
inferred← citeshttps://doi.org/10.1007/s00432-022-04253-1openalex-snapshot
Heterogeneous expression of ACE2, TMPRSS2, and FURIN at single-cell resolution in advanced non-small cell lung cancer
inferred← citeshttps://doi.org/10.1007/s00439-022-02439-8openalex-snapshot
Challenges in translational machine learning
inferred← citeshttps://doi.org/10.1007/s00508-021-01819-wopenalex-snapshot
Mutant strains of SARS-CoV-2 are more prone to infect obese patient: a review
inferred← citeshttps://doi.org/10.1007/s00508-021-01875-2openalex-snapshot
Alterations of the male and female reproductive systems induced by COVID-19
inferred← citeshttps://doi.org/10.1007/s00535-021-01760-9openalex-snapshot
COVID-19-associated liver injury: from bedside to bench
inferred← citeshttps://doi.org/10.1007/s00580-021-03269-2openalex-snapshot
Revealed pathophysiological mechanisms of crosslinking interaction of affected vital organs in COVID-19
inferred← citeshttps://doi.org/10.1007/s00580-021-03311-3openalex-snapshot
Exosomes and COVID-19: challenges and opportunities
inferred← citeshttps://doi.org/10.1007/s00705-021-05036-8openalex-snapshot
The emerging role of probiotics as a mitigation strategy against coronavirus disease 2019 (COVID-19)
inferred← citeshttps://doi.org/10.1007/s00705-022-05545-0openalex-snapshot
Molecular mechanisms involved in anosmia induced by SARS-CoV-2, with a focus on the transmembrane serine protease TMPRSS2
inferred← citeshttps://doi.org/10.1007/s10096-020-03883-yopenalex-snapshot
Searching therapeutic strategy of new coronavirus pneumonia from angiotensin-converting enzyme 2: the target of COVID-19 and SARS-CoV
inferred← citeshttps://doi.org/10.1007/s10096-020-04138-6openalex-snapshot
COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection
inferred← citeshttps://doi.org/10.1007/s10096-021-04264-9openalex-snapshot
Epigenetic alterations and genetic variations of angiotensin-converting enzyme 2 (ACE2) as a functional receptor for SARS-CoV-2: potential clinical implications
inferred← citeshttps://doi.org/10.1007/s10157-020-01904-wopenalex-snapshot
Clinical features of hemodialysis patients with COVID-19: a single-center retrospective study on 32 patients
inferred← citeshttps://doi.org/10.1007/s10439-022-03094-wopenalex-snapshot
Advances in Targeting ACE2 for Developing COVID-19 Therapeutics
inferred← citeshttps://doi.org/10.1007/s10557-020-07073-yopenalex-snapshot
Impact of COVID-19 on the Cardiovascular System: A Review of Available Reports
inferred← citeshttps://doi.org/10.1007/s10561-020-09869-6openalex-snapshot
Effect of different human tissue processing techniques on SARS-CoV-2 inactivation-review
inferred← citeshttps://doi.org/10.1007/s10561-021-09964-2openalex-snapshot
The estimated risk of SARS-CoV- 2 infection via cornea transplant in Canada
inferred← citeshttps://doi.org/10.1007/s10571-020-00861-yopenalex-snapshot
COVID-19, Angiotensin Receptor Blockers, and the Brain
inferred← citeshttps://doi.org/10.1007/s10571-020-00938-8openalex-snapshot
Coronavirus Disease 2019 (COVID-19) and Its Neuroinvasive Capacity: Is It Time for Melatonin?
inferred← citeshttps://doi.org/10.1007/s10571-023-01444-3openalex-snapshot
Microglial Inflammatory Responses to SARS‐CoV‐2 Infection: A Comprehensive Review
inferred← citeshttps://doi.org/10.1007/s10735-020-09915-3openalex-snapshot
COVID-19 and multiorgan failure: A narrative review on potential mechanisms
inferred← citeshttps://doi.org/10.1007/s10735-021-10003-3openalex-snapshot
COVID-19 and male reproductive system: pathogenic features and possible mechanisms
inferred← citeshttps://doi.org/10.1007/s10735-022-10088-4openalex-snapshot
Hemophagocytic lymphohistiocytosis diagnosed by bone marrow trephine biopsy in living post-COVID-19 patients: case report and mini-review
inferred← citeshttps://doi.org/10.1007/s10753-020-01337-3openalex-snapshot
Inflammation Triggered by SARS-CoV-2 and ACE2 Augment Drives Multiple Organ Failure of Severe COVID-19: Molecular Mechanisms and Implications
inferred← citeshttps://doi.org/10.1007/s10753-023-01949-5openalex-snapshot
ACE2 Expressed on Myeloid Cells Alleviates Sepsis-Induced Acute Liver Injury via the Ang-(1–7)–Mas Receptor Axis
inferred← citeshttps://doi.org/10.1007/s10787-020-00745-zopenalex-snapshot
A narrative review of the potential pharmacological influence and safety of ibuprofen on coronavirus disease 19 (COVID-19), ACE2, and the immune system: a dichotomy of expectation and reality
inferred← citeshttps://doi.org/10.1007/s10792-022-02607-9openalex-snapshot
Assessment of early and long-COVID related retinal neurodegeneration with optical coherence tomography
inferred← citeshttps://doi.org/10.1007/s10815-021-02097-1openalex-snapshot
The probable destructive mechanisms behind COVID-19 on male reproduction system and fertility
inferred← citeshttps://doi.org/10.1007/s10815-022-02517-wopenalex-snapshot
The impact of past COVID-19 infection on pregnancy rates in frozen embryo transfer cycles
inferred← citeshttps://doi.org/10.1007/s10840-022-01138-8openalex-snapshot
Heart rate variability and cardiac autonomic functions in post-COVID period
inferred← citeshttps://doi.org/10.1007/s10916-021-01707-wopenalex-snapshot
A Novel Block Imaging Technique Using Nine Artificial Intelligence Models for COVID-19 Disease Classification, Characterization and Severity Measurement in Lung Computed Tomography Scans on an Italian Cohort
inferred← citeshttps://doi.org/10.1007/s11010-021-04275-2openalex-snapshot
Role of ACE2-Ang (1–7)-Mas axis in post-COVID-19 complications and its dietary modulation
inferred← citeshttps://doi.org/10.1007/s11010-022-04485-2openalex-snapshot
Association of underlying comorbidities and progression of COVID-19 infection amongst 2586 patients hospitalised in the National Capital Region of India: a retrospective cohort study
inferred← citeshttps://doi.org/10.1007/s11010-022-04610-1openalex-snapshot
Respiratory issues in patients with multiple sclerosis as a risk factor during SARS-CoV-2 infection: a potential role for exercise
inferred← citeshttps://doi.org/10.1007/s11033-020-05478-4openalex-snapshot
Expressions and significances of the angiotensin-converting enzyme 2 gene, the receptor of SARS-CoV-2 for COVID-19
inferred← citeshttps://doi.org/10.1007/s11033-021-06358-1openalex-snapshot
Silent hypoxia in COVID-19: pathomechanism and possible management strategy
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