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CASK regulates Notch pathway and functions as a tumor promoter in pancreatic cancer
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1521-1878(199803)20:3<235::aid-bies7>3.0.co;2-qopenalex-snapshot
Reeler: new tales on an old mutant mouse
inferredcites →https://doi.org/10.1002/jso.24623openalex-snapshot
Current and future therapies for advanced pancreatic cancer
inferredcites →https://doi.org/10.1002/mc.20785openalex-snapshot
Pancreatic cancer: Overview of descriptive epidemiology
inferredcites →https://doi.org/10.1007/s13277-014-2179-3openalex-snapshot
High expression of CASK correlates with progression and poor prognosis of colorectal cancer
inferredcites →https://doi.org/10.1016/j.bbrc.2005.01.014openalex-snapshot
CASK inhibits ECV304 cell growth and interacts with Id1
inferredcites →https://doi.org/10.1016/j.canep.2014.08.010openalex-snapshot
The association between smokeless tobacco use and pancreatic adenocarcinoma: A systematic review
inferredcites →https://doi.org/10.1016/j.canlet.2014.01.004openalex-snapshot
Cancer statistics: Current diagnosis and treatment of pancreatic cancer in Shanghai, China
inferredcites →https://doi.org/10.1016/j.jmb.2011.07.005openalex-snapshot
The Molecular Basis of the Caskin1 and Mint1 Interaction with CASK
inferredcites →https://doi.org/10.1016/j.molmed.2013.03.003openalex-snapshot
Notch signaling in pancreatic cancer: oncogene or tumor suppressor?
inferredcites →https://doi.org/10.1016/j.neuron.2008.09.026openalex-snapshot
Interaction between Reelin and Notch Signaling Regulates Neuronal Migration in the Cerebral Cortex
inferredcites →https://doi.org/10.1016/j.pan.2013.11.011openalex-snapshot
Notch pathway activation is associated with pancreatic cancer treatment failure
inferredcites →https://doi.org/10.1016/s1470-2045(17)30084-0openalex-snapshot
Vandetanib plus gemcitabine versus placebo plus gemcitabine in locally advanced or metastatic pancreatic carcinoma (ViP): a prospective, randomised, double-blind, multicentre phase 2 trial
inferredcites →https://doi.org/10.1038/23716openalex-snapshot
Notch signalling controls pancreatic cell differentiation
inferredcites →https://doi.org/10.1038/ng.194openalex-snapshot
Mutations of CASK cause an X-linked brain malformation phenotype with microcephaly and hypoplasia of the brainstem and cerebellum
inferredcites →https://doi.org/10.1038/nrc3035openalex-snapshot
Notch signalling in solid tumours: a little bit of everything but not all the time
inferredcites →https://doi.org/10.1042/bst20130061openalex-snapshot
Structural constraints and functional divergences in CASK evolution
inferredcites →https://doi.org/10.1073/pnas.0611003104openalex-snapshot
Deletion of CASK in mice is lethal and impairs synaptic function
inferredcites →https://doi.org/10.1074/jbc.m202435200openalex-snapshot
Syndecan-2 Mediates Adhesion and Proliferation of Colon Carcinoma Cells
inferredcites →https://doi.org/10.1083/jcb.142.1.129openalex-snapshot
Human CASK/LIN-2 Binds Syndecan-2 and Protein 4.1 and Localizes to the Basolateral Membrane of Epithelial Cells
inferredcites →https://doi.org/10.1093/jnci/djt123openalex-snapshot
Hyperglycemia, Insulin Resistance, Impaired Pancreatic β-Cell Function, and Risk of Pancreatic Cancer
inferredcites →https://doi.org/10.1126/science.1072356openalex-snapshot
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
inferredcites →https://doi.org/10.1158/1535-7163.mct-14-0915openalex-snapshot
Xanthohumol-Mediated Suppression of Notch1 Signaling Is Associated with Antitumor Activity in Human Pancreatic Cancer Cells
inferredcites →https://doi.org/10.1242/jcs.025643openalex-snapshot
The MAGUK-family protein CASK is targeted to nuclei of the basal epidermis and controls keratinocyte proliferation
inferredcites →https://doi.org/10.1371/journal.pone.0042697openalex-snapshot
Hypoxia-Induced Alternative Splicing in Endothelial Cells
inferredcites →https://doi.org/10.1371/journal.pone.0085502openalex-snapshot
The MEK/ERK Pathway Promotes NOTCH Signalling in Pancreatic Cancer Cells
inferredcites →https://doi.org/10.1387/ijdb.12141438openalex-snapshot
Genetic studies define MAGUK proteins as regulators of epithelial cell polarity
inferredcites →https://doi.org/10.1517/13543784.15.11.1395openalex-snapshot
Pancreatic cancer: a review of recent advances
inferredcites →https://doi.org/10.1523/jneurosci.16-08-02488.1996openalex-snapshot
CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins
inferredcites →https://doi.org/10.2174/092986706777585040openalex-snapshot
The Role of the MAGUK Protein CASK in Neural Development and Synaptic Function
inferredcites →https://doi.org/10.2478/v10039-009-0026-3openalex-snapshot
Targeting Notch signaling in pancreatic cancer patients - rationale for new therapy
inferredcites →https://doi.org/10.3322/caac.21492openalex-snapshot
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
inferredcites →https://doi.org/10.3892/ol.2020.12239openalex-snapshot
Mass spectrum analysis of membrane proteins reveals that CASK, CD36 and EPB42 are differentially expressed in pancreatic adenocarcinoma
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4627112openalex-extracted
The Biological Functions and Regulatory Mechanisms of CASK in Various Diseases
inferred← citeshttps://doi.org/10.1002/ddr.70373openalex-snapshot
Dauriporphine Suppresses Cell Proliferation, Metastasis, and Stemness of Non‐Small Cell Lung Cancer Through the Regulation of the USP7/CASK
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e36234openalex-snapshot
Comprehensive analysis and experimental verification of the mechanism of anoikis related genes in pancreatic cancer
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.143965openalex-snapshot
CASK promotes prostate cancer progression via kinase-dependent activation of AKT
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.1c00845openalex-snapshot
Design and Development of a Chemical Probe for Pseudokinase Ca2+/calmodulin-Dependent Ser/Thr Kinase
inferred← citeshttps://doi.org/10.1038/s41419-022-05379-3openalex-snapshot
RHBDL2 promotes the proliferation, migration, and invasion of pancreatic cancer by stabilizing the N1ICD via the OTUD7B and activating the Notch signaling pathway
inferred← citeshttps://doi.org/10.1093/nar/gkac737openalex-snapshot
The androgen receptor couples promoter recruitment of RNA processing factors to regulation of alternative polyadenylation at the 3' end of transcripts
inferred← citeshttps://doi.org/10.1111/jcmm.70794openalex-snapshot
The Physiological and Pathological Mechanisms of LIN 2, LIN 7, LIN 10 and Their Tripartite Complex
inferred← citeshttps://doi.org/10.1155/2022/5443709openalex-snapshot
Prediction of Response to Radiotherapy by Characterizing the Transcriptomic Features in Clinical Tumor Samples across 15 Cancer Types
inferred← citeshttps://doi.org/10.1155/ijog/9346050openalex-snapshot
Molecular Basis of Aggressiveness in Pituitary Adenomas and Its Association With the Immune Microenvironment
inferred← citeshttps://doi.org/10.1186/s13064-023-00174-yopenalex-snapshot
Drosophila CASK regulates brain size and neuronal morphogenesis, providing a genetic model of postnatal microcephaly suitable for drug discovery
inferred← citeshttps://doi.org/10.18632/aging.203167openalex-snapshot
LncRNA HCG11/miR-579-3p/MDM2 axis modulates malignant biological properties in pancreatic carcinoma via Notch/Hes1 signaling pathway
inferred← citeshttps://doi.org/10.26508/lsa.202403122openalex-snapshot
Novel determinants of NOTCH1 trafficking and signaling in breast epithelial cells
inferred← citeshttps://doi.org/10.3389/fonc.2026.1693570openalex-snapshot
Identification and validation of the potential therapeutic value of CASK in osteosarcoma: a computational analysis and in vitro experiments
inferred← citeshttps://doi.org/10.3390/genes14081656openalex-snapshot
Diverse Clinical Phenotypes of CASK-Related Disorders and Multiple Functional Domains of CASK Protein
inferred← citeshttps://doi.org/10.3390/ijms25020840openalex-snapshot
Aptamer-Based Recognition of Breast Tumor Cells: A New Era for Breast Cancer Diagnosis
inferred← citeshttps://doi.org/10.4236/jbm.2024.1211034openalex-snapshot
Differential Expressed Genes in ECV304 Endothelial-Like Cells Infected with Herpes Simplex Virus Type 2
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