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A Multiphase Microscopic Diffusion Model for Stratum Corneum permeability. I. Formulation, Solution, and Illustrative Results for Representative Compounds
A multiphase microscopic diffusion model for stratum corneum permeability. II. estimation of physicochemical parameters, and application to a large permeability database
First‐principles, structure‐based transdermal transport model to evaluate lipid partition and diffusion coefficients of hydrophobic permeants solely from stratum corneum permeation experiments
Diffusion Modelling of Percutaneous Absorption Kinetics: 4. Effects of a Slow Equilibration Process Within Stratum Corneum on Absorption and Desorption Kinetics
Percutaneous Penetration of N-Nitrosodiethanolamine through Human Skin (in Vitro): Comparison of Finite and Infinite Dose Applications from Cosmetic Vehicles
Epidermal permeability: Penetrant structure relationships. 2. The effect of h-bonding groups in penetrants on their diffusion through the stratum corneum
Epidermal permeability — Penetrant structure relationships: 3. The effect of hydrogen bonding interactions and molecular size on diffusion across the stratum corneum
Lipid organization in human and porcine stratum corneum differs widely, while lipid mixtures with porcine ceramides model human stratum corneum lipid organization very closely
In-silico model of skin penetration based on experimentally determined input parameters. Part II: Mathematical modelling of in-vitro diffusion experiments. Identification of critical input parameters
Diffusion modeling of percutaneous absorption kinetics. 1. Effects of flow rate, receptor sampling rate, and viable epidermal resistance for a constant donor concentration
Chemical Structure and Skin Penetrating Capacity of a Short Series of Organic Phosphates and Phosphoric Acid**From the Dermal Toxicity Branch, DP, Bureau of Scientific Research, Food and Drug Administration, Washington, D.C. and the Field Toxicology Branch, Toxicology Division, Chemical Research &…
Elevated Human Tissue Kallikrein Levels in the Stratum Corneum and Serum of Peeling Skin Syndrome-Type B Patients Suggests an Over-desquamation of Corneocytes
Physiologically‐Based Pharmacokinetic Modeling to Support Determination of Bioequivalence for Dermatological Drug Products: Scientific and Regulatory Considerations
In Silico Pharmacokinetic Analysis of Topical Administration of Liposomal Nano-Drug across Different Human Skin Types: A Compartmental Numerical Approach
Evaluation on the reliability of the permeability coefficient (Kp) to assess the percutaneous penetration property of chemicals on the basis of Flynn’s dataset
In Silico Modelling of Transdermal and Systemic Kinetics of Topically Applied Solutes: Model Development and Initial Validation for Transdermal Nicotine
Kinetics of Clobetasol-17-Propionate in Psoriatic Lesional and Non-Lesional Skin Assessed by Dermal Open Flow Microperfusion with Time and Space Resolution
Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum
A review of the current state of the art of physiologically-based tests for measuring human dermal in vitro bioavailability of polycyclic aromatic hydrocarbons (PAH) in soil
Estimation of in vivo dose of dermally applied chemicals leading to estrogen/androgen receptor-mediated toxicity from in vitro data—Illustration with four reproductive toxicants
Partition coefficient and diffusion coefficient determinations of 50 compounds in human intact skin, isolated skin layers and isolated stratum corneum lipids
Percutaneous penetration of drugs applied in transdermal delivery systems: an in vivo based approach for evaluating computer generated penetration models
Biointerface-engineered gold and silver nanoparticles for skin cancer therapy: linking nano–biointerface design to therapeutic function and clinical translation
Biocatálise na produção de moléculas orgânicas: oxidorredutases de fungos marinhos para a síntese de álcoois quirais e lipase de Candida antarctica na produção de amidas fenólicas graxas
The Influence of the Variable Wettability Characteristics of Layers on the Transport of Nanoparticles in the Context of Drug Delivery in Skin Structures
Evaluation in vitro de la sensibilisation cutanée aux xénobiotiques : Pertinence d’un modèle de co-culture épiderme reconstruit humain/cellules THP-1
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