On the public citation graph

Mitofusin 2 confers the suppression of microglial activation by cannabidiol: Insights from in vitro and in vivo models

https://doi.org/10.1016/j.bbi.2022.06.003

0 signed · 85 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/biof.1597openalex-snapshot

The effects of statins on microglial cells to protect against neurodegenerative disorders: A mechanistic review

inferredcites →https://doi.org/10.1002/glia.23940openalex-snapshot

Altered astrocytic function in experimental neuroinflammation and multiple sclerosis

inferredcites →https://doi.org/10.1002/ptr.5095openalex-snapshot

Cannabidiol Promotes Amyloid Precursor Protein Ubiquitination and Reduction of Beta Amyloid Expression in SHSY5YAPP+ Cells Through PPARγ Involvement

inferredcites →https://doi.org/10.1007/s00213-017-4697-3openalex-snapshot

Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents

inferredcites →https://doi.org/10.1007/s11481-021-10023-6openalex-snapshot

Effects of Orally Administered Cannabidiol on Neuroinflammation and Intestinal Inflammation in the Attenuation of Experimental Autoimmune Encephalomyelitis

inferredcites →https://doi.org/10.1007/s12035-013-8514-7openalex-snapshot

Cannabidiol Normalizes Caspase 3, Synaptophysin, and Mitochondrial Fission Protein DNM1L Expression Levels in Rats with Brain Iron Overload: Implications for Neuroprotection

inferredcites →https://doi.org/10.1007/s12079-021-00622-6openalex-snapshot

Endocannabinoid signaling pathways: beyond CB1R and CB2R

inferredcites →https://doi.org/10.1007/s13311-015-0377-3openalex-snapshot

Molecular Targets of Cannabidiol in Neurological Disorders

inferredcites →https://doi.org/10.1016/j.bbi.2019.12.009openalex-snapshot

Crotoxin down-modulates pro-inflammatory cells and alleviates pain on the MOG35-55-induced experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis

inferredcites →https://doi.org/10.1016/j.bbi.2020.07.010openalex-snapshot

Chronic mechanical hypersensitivity in experimental autoimmune encephalomyelitis is regulated by disease severity and neuroinflammation

inferredcites →https://doi.org/10.1016/j.cell.2013.09.004openalex-snapshot

Mitochondrial Dynamics Controlled by Mitofusins Regulate Agrp Neuronal Activity and Diet-Induced Obesity

inferredcites →https://doi.org/10.1016/j.ejcb.2021.151185openalex-snapshot

Cannabidiol activates PINK1-Parkin-dependent mitophagy and mitochondrial-derived vesicles

inferredcites →https://doi.org/10.1016/j.freeradbiomed.2018.06.023openalex-snapshot

Cannabidiol induced apoptosis in human monocytes through mitochondrial permeability transition pore-mediated ROS production

inferredcites →https://doi.org/10.1016/j.freeradbiomed.2020.01.014openalex-snapshot

Echinacoside attenuates inflammatory response in a rat model of cervical spondylotic myelopathy via inhibition of excessive mitochondrial fission

inferredcites →https://doi.org/10.1016/j.freeradbiomed.2020.12.018openalex-snapshot

Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway

inferredcites →https://doi.org/10.1016/j.intimp.2020.107176openalex-snapshot

Roflupram, a novel phosphodiesterase 4 inhibitor, inhibits lipopolysaccharide-induced neuroinflammatory responses through activation of the AMPK/Sirt1 pathway

inferredcites →https://doi.org/10.1016/j.jaut.2019.04.020openalex-snapshot

Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE)

inferredcites →https://doi.org/10.1016/j.phrs.2018.01.003openalex-snapshot

Highlighting the endoplasmic reticulum-mitochondria connection: Focus on Mitofusin 2

inferredcites →https://doi.org/10.1016/j.redox.2020.101818openalex-snapshot

Miro1-mediated mitochondrial positioning supports subcellular redox status

inferredcites →https://doi.org/10.1016/j.toxlet.2013.02.003openalex-snapshot

JNK and p38 MAPK regulate oxidative stress and the inflammatory response in chlorpyrifos-induced apoptosis

inferredcites →https://doi.org/10.1021/acschemneuro.7b00065openalex-snapshot

Roflupram, a Phosphodiesterase 4 Inhibitior, Suppresses Inflammasome Activation through Autophagy in Microglial Cells

inferredcites →https://doi.org/10.1038/s41419-019-2024-0openalex-snapshot

Cannabidiol directly targets mitochondria and disturbs calcium homeostasis in acute lymphoblastic leukemia

inferredcites →https://doi.org/10.1038/s41582-019-0253-6openalex-snapshot

When encephalitogenic T cells collaborate with microglia in multiple sclerosis

inferredcites →https://doi.org/10.1038/s41582-021-00463-2openalex-snapshot

Multifaceted microglia — key players in primary brain tumour heterogeneity

inferredcites →https://doi.org/10.1038/sj.bjp.0707442openalex-snapshot

The diverse CB 1 and CB 2 receptor pharmacology of three plant cannabinoids: Δ 9 ‐tetrahydrocannabinol, cannabidiol and Δ 9 ‐tetrahydrocannabivarin

inferredcites →https://doi.org/10.1073/pnas.1108220109openalex-snapshot

Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis

inferredcites →https://doi.org/10.1084/jem.20110367openalex-snapshot

Mitochondrial reactive oxygen species drive proinflammatory cytokine production

inferredcites →https://doi.org/10.1089/can.2020.0181openalex-snapshot

Modulatory Potential of Cannabidiol on the Opioid-Induced Inflammatory Response

inferredcites →https://doi.org/10.1093/brain/awz393openalex-snapshot

Microglia and macrophage phenotypes in intracerebral haemorrhage injury: therapeutic opportunities

inferredcites →https://doi.org/10.1093/hmg/ddz008openalex-snapshot

MFN2 mutations in Charcot–Marie–Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics

inferredcites →https://doi.org/10.1093/ijnp/pyy092openalex-snapshot

Inhibition of Phosphodiesterase 4 by FCPR03 Alleviates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors and Prevents Dendritic Spine Loss in Mice Hippocampi

inferredcites →https://doi.org/10.1111/bph.14983openalex-snapshot

Roflupram exerts neuroprotection via activation of CREB/PGC‐1α signalling in experimental models of Parkinson's disease

inferredcites →https://doi.org/10.1111/bph.15178openalex-snapshot

ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020

inferredcites →https://doi.org/10.1111/j.1365-2990.2008.00987.xopenalex-snapshot

Review: Mitochondria and disease progression in multiple sclerosis

inferredcites →https://doi.org/10.1111/j.1476-5381.2012.02146.xopenalex-snapshot

Role and interactions of annexin A 1 and oestrogens in the manifestation of sexual dimorphisms in cerebral and systemic inflammation

inferredcites →https://doi.org/10.1111/jnc.12361openalex-snapshot

Mitochondrial dynamics modulate the expression of pro‐inflammatory mediators in microglial cells

inferredcites →https://doi.org/10.1111/jnc.13242openalex-snapshot

Microglial Hv1 proton channel promotes cuprizone‐induced demyelination through oxidative damage

inferredcites →https://doi.org/10.1176/appi.ajp.2017.17030325openalex-snapshot

Cannabidiol (CBD) as an Adjunctive Therapy in Schizophrenia: A Multicenter Randomized Controlled Trial

inferredcites →https://doi.org/10.1186/1742-2094-8-5openalex-snapshot

Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study

inferredcites →https://doi.org/10.1186/2042-6410-5-4openalex-snapshot

Sex differences in a mouse model of multiple sclerosis: neuropathic pain behavior in females but not males and protection from neurological deficits during proestrus

inferredcites →https://doi.org/10.1186/s12974-021-02309-6openalex-snapshot

The semantics of microglia activation: neuroinflammation, homeostasis, and stress

inferredcites →https://doi.org/10.1186/s13024-018-0238-8openalex-snapshot

Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex

inferredcites →https://doi.org/10.1523/jneurosci.2324-19.2020openalex-snapshot

Neuronal Mitochondria Modulation of LPS-Induced Neuroinflammation

inferredcites →https://doi.org/10.3389/fendo.2019.00420openalex-snapshot

Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1

inferredcites →https://doi.org/10.3389/fimmu.2021.570425openalex-snapshot

Peroxisome Proliferator-Activated Receptor-δ Deficiency in Microglia Results in Exacerbated Axonal Injury and Tissue Loss in Experimental Autoimmune Encephalomyelitis

inferredcites →https://doi.org/10.3390/ijms22094876openalex-snapshot

The (Poly)Pharmacology of Cannabidiol in Neurological and Neuropsychiatric Disorders: Molecular Mechanisms and Targets

inferredcites →https://doi.org/10.3390/jcm9030740openalex-snapshot

The Role of Mitochondria in Inflammation: From Cancer to Neurodegenerative Disorders

inferredcites →https://doi.org/10.3390/pharmaceutics12030265openalex-snapshot

Cannabinoids, Blood–Brain Barrier, and Brain Disposition

inferredcites →https://doi.org/10.4155/fmc.09.93openalex-snapshot

Cannabinoids as Novel Anti-Inflammatory Drugs

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4593656openalex-extracted

inferred← citeshttps://doi.org/10.1002/adfm.202505499openalex-snapshot

Intranasally Delivered Echinacoside Micelles Modulate Mitochondrial Fusion Against Postoperative Cognitive Dysfunction

inferred← citeshttps://doi.org/10.1002/glia.24572openalex-snapshot

Inhibition of phosphodiesterase 4 attenuates aquaporin 4 expression and astrocyte swelling following cerebral ischemia/reperfusion injury

inferred← citeshttps://doi.org/10.1002/mco2.70055openalex-snapshot

Metabolic reprogramming in cancer and senescence

inferred← citeshttps://doi.org/10.1007/s12035-024-04466-0openalex-snapshot

Mitofusin 2 Mediates the Protective Effect of NR6A1 Silencing Against Neuronal Injury in Experimental Stroke Models

inferred← citeshttps://doi.org/10.1016/j.bbi.2024.05.016openalex-snapshot

Cannabidiol ameliorates PTSD-like symptoms by inhibiting neuroinflammation through its action on CB2 receptors in the brain of male mice

inferred← citeshttps://doi.org/10.1016/j.bbi.2025.02.007openalex-snapshot

PDE4 inhibition alleviates HMGB1/C1q/C3-mediated excessive phagocytic pruning of synapses by microglia and depressive-like behaviors in mice

inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117188openalex-snapshot

Isoliquiritigenin alleviates experimental autoimmune encephalomyelitis by modulating inflammatory and neuroprotective reactive astrocytes

inferred← citeshttps://doi.org/10.1016/j.brainres.2023.148674openalex-snapshot

Potential biomaterials and experimental animal models for inventing new drug delivery approaches in the neurodegenerative disorder: Multiple sclerosis

inferred← citeshttps://doi.org/10.1016/j.cellimm.2024.104812openalex-snapshot

The mechanism by which cannabidiol (CBD) suppresses TNF-α secretion involves inappropriate localization of TNF-α converting enzyme (TACE)

inferred← citeshttps://doi.org/10.1016/j.expneurol.2023.114654openalex-snapshot

Involvement of CKS1B in the anti-inflammatory effects of cannabidiol in experimental stroke models

inferred← citeshttps://doi.org/10.1016/j.jep.2025.121067openalex-snapshot

Cannabidiol attenuates the LPS/D-Galactosamine-induced acute liver injury by inhibiting parkin-mediated ubiquitination of MFN2

inferred← citeshttps://doi.org/10.1016/j.mad.2026.112206openalex-snapshot

Cell-specific energy crisis in the ageing brain: Mitochondrial dynamics drives neuron-glia metabolic uncoupling and neurodegeneration

inferred← citeshttps://doi.org/10.1016/j.neuint.2024.105769openalex-snapshot

Cannabidiol prevents LPS-induced inflammation by inhibiting the NLRP3 inflammasome and iNOS activity in BV2 microglia cells via CB2 receptors and PPARγ

inferred← citeshttps://doi.org/10.1016/j.neulet.2024.137643openalex-snapshot

Microglia nuclear receptor corepressor 1 deficiency alleviates neuroinflammation in mice

inferred← citeshttps://doi.org/10.1016/j.phymed.2023.154797openalex-snapshot

Modified Erchen decoction ameliorates cognitive dysfunction in vascular dementia rats via inhibiting JAK2/STAT3 and JNK/BAX signaling pathways

inferred← citeshttps://doi.org/10.1016/j.phymed.2024.155844openalex-snapshot

Buqi Huoxue Tongnao prescription protects against chronic cerebral hypoperfusion via regulating PI3K/AKT and LXRα/CYP7A1 signaling pathways

inferred← citeshttps://doi.org/10.1016/j.ymthe.2025.08.001openalex-snapshot

Harnessing patient-derived antibodies-induced microglial complement 1q expression: Novel therapy for anti-NMDAR encephalitis

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5c00137openalex-snapshot

Discovery of Limonoids from Xylocarpus granatum as Potential Leads against Neuroinflammation

inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.3c00244openalex-snapshot

Therapeutic Polymer-Based Cannabidiol Formulation: Tackling Neuroinflammation Associated with Ischemic Events in the Brain

inferred← citeshttps://doi.org/10.1021/acschemneuro.3c00454openalex-snapshot

JE-133 Suppresses LPS-Induced Neuroinflammation Associated with the Regulation of JAK/STAT and Nrf2 Signaling Pathways

inferred← citeshttps://doi.org/10.1038/s41380-026-03733-xopenalex-snapshot

Effects of cannabidiol on anxiety- and depressive-like behaviors and cognition: a systematic review and meta-analysis of preclinical studies

inferred← citeshttps://doi.org/10.1038/s41401-022-01004-3openalex-snapshot

Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats

inferred← citeshttps://doi.org/10.1038/s41598-026-36666-0openalex-snapshot

Cannabidiol mitigates high-fat-diet-induced early-stage inflammation in two adipose tissue fat depots of Wistar rats

inferred← citeshttps://doi.org/10.1080/1354750x.2022.2164354openalex-snapshot

Leaf extract ofAnacardium occidentaleameliorates biomarkers of neuroinflammation, memory loss, and neurobehavioral deficit in N(ω)-nitro-L-arginine methyl ester (L-NAME) treated rats

inferred← citeshttps://doi.org/10.1080/14786419.2025.2565264openalex-snapshot

The phytochemical characteristics of Swertia mussotii Franch. and the potential for treating neuroinflammation in vitro through the NF-κB pathway

inferred← citeshttps://doi.org/10.1186/s12951-025-03408-9openalex-snapshot

Coordination acid-engineered Prussian Blue affects glycometabolic reprogramming in microglia for epileptic treatment

inferred← citeshttps://doi.org/10.1186/s12974-022-02613-9openalex-snapshot

Mitochondrial dysfunction in microglia: a novel perspective for pathogenesis of Alzheimer’s disease

inferred← citeshttps://doi.org/10.1186/s40779-024-00536-5openalex-snapshot

Mitochondrial quality control in human health and disease

inferred← citeshttps://doi.org/10.1186/s42238-025-00332-5openalex-snapshot

The effects of cannabidiol on nitric oxide synthases: a narrative review on therapeutic implications for inflammation and oxidative stress in health and disease

inferred← citeshttps://doi.org/10.1186/s42238-026-00445-5openalex-snapshot

Cannabidiol and other non-psychotropic cannabinoids from Cannabis sativa as therapeutics for microglial-mediated neuroinflammation and neurodegeneration

inferred← citeshttps://doi.org/10.14814/phy2.70310openalex-snapshot

Alterations of circulating exosomal microRNAs in an LPS‐induced depression model of male mice: Potential role in the anti‐depressive effects of acupuncture

inferred← citeshttps://doi.org/10.21203/rs.3.rs-7197783/v1openalex-snapshot

Cannabidiol improves short-term memory in a Streptozotocin-induced animal model of Alzheimer’s disease

inferred← citeshttps://doi.org/10.2147/nss.s485952openalex-snapshot

Exosomes from IH- Induced bEnd3 Cells Promote OSA Cognitive Impairment via miR-20a-5p/MFN2 Mediated Pyroptosis of HT22 Cells

inferred← citeshttps://doi.org/10.31083/j.jin2305091openalex-snapshot

The Role of Microglia with Mitochondrial Dysfunction and Its Therapeutic Prospects in Alzheimer's Disease

inferred← citeshttps://doi.org/10.3389/fphar.2023.1247550openalex-snapshot

Anti-oxidant effects of cannabidiol relevant to intracerebral hemorrhage

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.